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Information on EC 2.7.7.7 - DNA-directed DNA polymerase and Organism(s) Dictyostelium discoideum

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EC Tree
     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.7 Nucleotidyltransferases
                2.7.7.7 DNA-directed DNA polymerase
IUBMB Comments
Catalyses DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time. Cannot initiate a chain de novo. Requires a primer, which may be DNA or RNA. See also EC 2.7.7.49 RNA-directed DNA polymerase.
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This record set is specific for:
Dictyostelium discoideum
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Word Map
The taxonomic range for the selected organisms is: Dictyostelium discoideum
The enzyme appears in selected viruses and cellular organisms
Synonyms
dna polymerase alpha, dna polymerase beta, dna polymerase iii, pol beta, klenow fragment, dna polymerase delta, taq dna polymerase, pol delta, pol alpha, dna polymerase gamma, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
deoxynucleate polymerase
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deoxyribonucleate nucleotidyltransferase
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-
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deoxyribonucleic acid duplicase
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deoxyribonucleic acid polymerase
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deoxyribonucleic duplicase
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deoxyribonucleic polymerase
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deoxyribonucleic polymerase I
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DNA duplicase
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DNA nucleotidyltransferase
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DNA nucleotidyltransferase (DNA-directed)
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DNA polmerase beta
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DNA polymerase
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DNA polymerase alpha
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DNA polymerase gamma
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DNA polymerase I
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DNA polymerase II
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-
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DNA polymerase III
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DNA replicase
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-
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DNA-dependent DNA polymerase
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duplicase
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Klenow fragment
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nucleotidyltransferase, deoxyribonucleate
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Pol gamma
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sequenase
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Taq DNA polymerase
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Taq Pol I
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Tca DNA polymerase
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
nucleotidyl group transfer
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-
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SYSTEMATIC NAME
IUBMB Comments
deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed)
Catalyses DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time. Cannot initiate a chain de novo. Requires a primer, which may be DNA or RNA. See also EC 2.7.7.49 RNA-directed DNA polymerase.
CAS REGISTRY NUMBER
COMMENTARY hide
9012-90-2
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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
deoxynucleoside triphosphate + DNAn
diphosphate + DNAn+1
show the reaction diagram
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-
-
-
?
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
deoxynucleoside triphosphate + DNAn
diphosphate + DNAn+1
show the reaction diagram
-
-
-
-
?
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
DPOLA_DICDI
1509
0
172818
Swiss-Prot
other Location (Reliability: 2)
DPOD1_DICDI
1104
0
125346
Swiss-Prot
other Location (Reliability: 2)
DPOE1_DICDI
2380
0
275442
Swiss-Prot
other Location (Reliability: 1)
Q55AZ3_DICDI
2701
0
310024
TrEMBL
other Location (Reliability: 2)
Q1ZXF2_DICDI
509
0
58268
TrEMBL
other Location (Reliability: 1)
Q86KS9_DICDI
516
0
59092
TrEMBL
other Location (Reliability: 4)
Q8I7W9_DICDI
1369
0
156673
TrEMBL
other Location (Reliability: 2)
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Scovassi, A.I.; Plevani, P.; Bertazzoni, U.
Eukaryotic DNA polymerases
Trends Biochem. Sci.
1980
335-337
1980
Bos taurus, Saccharomyces cerevisiae, Dictyostelium discoideum, Euglena gracilis, Homo sapiens, Mammalia, Neurospora crassa, Physarum polycephalum, Tetrahymena pyriformis, Trypanosoma brucei, Ustilago maydis
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Manually annotated by BRENDA team