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Information on EC 2.7.7.6 - DNA-directed RNA polymerase and Organism(s) Arabidopsis thaliana
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2.7.7.6 DNA-directed RNA polymeraseIUBMB Comments
Catalyses DNA-template-directed extension of the 3'- end of an RNA strand by one nucleotide at a time. Can initiate a chain de novo. In eukaryotes, three forms of the enzyme have been distinguished on the basis of sensitivity to alpha-amanitin, and the type of RNA synthesized. See also EC 2.7.7.19 (polynucleotide adenylyltransferase) and EC 2.7.7.48 (RNA-directed RNA polymerase).
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Word Map
- 2.7.7.6
- chromatin
- histone
- rrna
- strand
-
rnaps
- nucleosome
- tata
- drosophila
-
pausing
- pre-mrnas
- tbp
-
nucleolar
- bacteriophage
-
polyadenylation
-
single-stranded
-
cyclin-dependent
-
holoenzyme
- cyclin
-
spacers
- helicase
-
fidelity
- polya
-
coactivator
-
protein-coding
-
transactivation
- adenovirus
- xenopus
- ribonucleoproteins
-
sequence-specific
-
stall
-
pause
-
chip-seq
- vaccinia
-
multisubunit
-
ribozyme
- heptapeptide
- duplex
-
h3k4me3
-
spliceosome
- nucleoplasm
-
run-on
-
supercoiled
-
trimethylation
-
subcomplexes
-
exonuclease
- heterochromatin
-
translesion
- medicine
- primase
- molecular biology
- analysis
- diagnostics
- drug development
-
misincorporation
-
proofread
- synthesis
The taxonomic range for the selected organisms is: Arabidopsis thaliana
The enzyme appears in selected viruses and cellular organisms
The enzyme appears in selected viruses and cellular organisms
Synonyms
rna polymerase ii, pol ii, t7 rna polymerase, rna polymerase i, pol iii, rna polymerase iii, pol i, rnapii, rnap ii, dna-dependent rna polymerase, 
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SYNONYM 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
C RNA formation factors
-
-
-
-
chloroplast soluble RNA polymerase
-
-
-
-
deoxyribonucleic acid-dependent ribonucleic acid polymerase
-
-
-
-
DNA-dependent ribonucleate nucleotidyltransferase
-
-
-
-
DNA-dependent RNA nucleotidyltransferase
-
-
-
-
DNA-dependent RNA polymerase
-
-
-
-
nucleotidyltransferase, ribonucleate
-
-
-
-
Pol II
-
-
-
-
ribonucleate nucleotidyltransferase
-
-
-
-
ribonucleate polymerase
-
-
-
-
ribonucleic acid formation factors, C
-
-
-
-
ribonucleic acid nucleotidyltransferase
-
-
-
-
ribonucleic acid polymerase
-
-
-
-
ribonucleic acid transcriptase
-
-
-
-
ribonucleic polymerase
-
-
-
-
ribonucleic transcriptase
-
-
-
-
RNA formation factors, C
-
-
-
-
RNA nucleotidyltransferase
-
-
-
-
RNA nucleotidyltransferase (DNA-directed)
-
-
-
-
RNA polymerase
-
-
-
-
RNA polymerase I
-
-
-
-
RNA polymerase II
-
-
-
-
RNA polymerase III
-
-
-
-
RNA transcriptase
-
-
-
-
RNAP
-
-
-
-
RNAP I
-
-
-
-
RNAP II
-
-
-
-
RNAP III
-
-
-
-
transcriptase
-
-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
nucleotidyl group transfer
-
-
-
-
SYSTEMATIC NAME
IUBMB Comments
nucleoside-triphosphate:RNA nucleotidyltransferase (DNA-directed)
Catalyses DNA-template-directed extension of the 3'- end of an RNA strand by one nucleotide at a time. Can initiate a chain de novo. In eukaryotes, three forms of the enzyme have been distinguished on the basis of sensitivity to alpha-amanitin, and the type of RNA synthesized. See also EC 2.7.7.19 (polynucleotide adenylyltransferase) and EC 2.7.7.48 (RNA-directed RNA polymerase).
CAS REGISTRY NUMBER
COMMENTARY
9014-24-8
-
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION
The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable).
The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable). NRPA1_ARATH
1670
0
187576
Swiss-Prot
Secretory Pathway (Reliability: 4)
NRPA2_ARATH
1178
0
132381
Swiss-Prot
other Location (Reliability: 1)
NRPB1_ARATH
1839
0
204626
Swiss-Prot
other Location (Reliability: 3)
NRPB2_ARATH
1188
0
135019
Swiss-Prot
other Location (Reliability: 2)
RPOB_ARATH
1072
0
121059
Swiss-Prot
other Location (Reliability: 2)
NRPC1_ARATH
1376
0
153006
Swiss-Prot
other Location (Reliability: 2)
NRPC2_ARATH
1161
0
130212
Swiss-Prot
other Location (Reliability: 1)
NRPD1_ARATH
1453
0
162521
Swiss-Prot
other Location (Reliability: 2)
NRPD2_ARATH
1172
0
132654
Swiss-Prot
other Location (Reliability: 2)
NRPE1_ARATH
1976
0
218228
Swiss-Prot
other Location (Reliability: 2)
RPD2B_ARATH
1119
0
126262
Swiss-Prot
other Location (Reliability: 2)
RPOA_ARATH
329
0
38137
Swiss-Prot
Mitochondrion (Reliability: 5)
RPOC2_ARATH
1376
0
156366
Swiss-Prot
other Location (Reliability: 3)
RPOC1_ARATH
680
0
78583
Swiss-Prot
Mitochondrion (Reliability: 5)
RPOT1_ARATH
976
0
110930
Swiss-Prot
Mitochondrion (Reliability: 2)
RPOT2_ARATH
1011
0
114521
Swiss-Prot
Chloroplast (Reliability: 3)
RPOT3_ARATH
993
0
112624
Swiss-Prot
Chloroplast (Reliability: 1)
A0A1B1W4T7_ARATH
681
0
78682
TrEMBL
Mitochondrion (Reliability: 5)
A0A514YJI3_ARATH
1376
0
156355
TrEMBL
other Location (Reliability: 3)
A0A8F5S3Q9_ARATH
1062
0
120435
TrEMBL
other Location (Reliability: 2)
Q6LAJ6_ARATH
282
0
31886
TrEMBL
Chloroplast (Reliability: 1)
A0A8F5P2G6_ARATH
1383
0
157291
TrEMBL
other Location (Reliability: 5)
A0A8F5Z9B4_ARATH
696
0
80858
TrEMBL
Mitochondrion (Reliability: 5)
A0A1P8ANM8_ARATH
1145
0
127410
TrEMBL
other Location (Reliability: 2)
A0A178VIB8_ARATH
845
1
95132
TrEMBL
other Location (Reliability: 2)
A0A178VIN8_ARATH
995
1
112036
TrEMBL
other Location (Reliability: 2)
Q8RXB9_ARATH
305
0
34267
TrEMBL
Mitochondrion (Reliability: 2)
A0A178V7U2_ARATH
2011
1
225784
TrEMBL
Secretory Pathway (Reliability: 1)
A0A1P8AYR1_ARATH
1775
0
196241
TrEMBL
other Location (Reliability: 2)
A0A1P8ANM9_ARATH
1439
0
161054
TrEMBL
other Location (Reliability: 2)
A0A178VGQ7_ARATH
148
0
16933
TrEMBL
other Location (Reliability: 5)
A0A178V2G7_ARATH
1188
0
135019
TrEMBL
other Location (Reliability: 2)
A0A654EVL5_ARATH
992
0
112412
TrEMBL
Chloroplast (Reliability: 1)
A0A8F5V8S3_ARATH
1060
0
120475
TrEMBL
other Location (Reliability: 2)
A0A178UYS0_ARATH
1839
0
204626
TrEMBL
other Location (Reliability: 3)
A0A7G2F1C7_ARATH
1648
0
187757
TrEMBL
other Location (Reliability: 2)
A0A178WQL3_ARATH
976
0
110879
TrEMBL
Mitochondrion (Reliability: 3)
A0A178VA17_ARATH
1172
0
132654
TrEMBL
other Location (Reliability: 2)
A0A654G1D3_ARATH
1051
0
119168
TrEMBL
Chloroplast (Reliability: 4)
A0A5S9YGT2_ARATH
1376
0
153006
TrEMBL
other Location (Reliability: 2)
A0A8F5GFL0_ARATH
1376
0
156297
TrEMBL
other Location (Reliability: 3)
A0A1P8ANM7_ARATH
1213
0
135997
TrEMBL
other Location (Reliability: 2)
A0A1I9LME9_ARATH
1657
0
186044
TrEMBL
other Location (Reliability: 3)
A0A8F5P3A9_ARATH
332
0
38365
TrEMBL
Mitochondrion (Reliability: 3)
A0A178VUS8_ARATH
1970
0
217571
TrEMBL
other Location (Reliability: 2)
F4JXF8_ARATH
1391
0
154618
TrEMBL
other Location (Reliability: 2)
F4KB75_ARATH
1051
0
119152
TrEMBL
Chloroplast (Reliability: 3)
Q9FWB0_ARATH
75
0
8487
TrEMBL
other Location (Reliability: 2)
A0A654FIP6_ARATH
1657
0
186044
TrEMBL
other Location (Reliability: 3)
A0A7G2EIR8_ARATH
1671
0
186567
TrEMBL
other Location (Reliability: 2)
Q3ZVA6_ARATH
60
0
6818
TrEMBL
other Location (Reliability: 2)
A0A8F5GHA9_ARATH
680
0
78583
TrEMBL
Mitochondrion (Reliability: 5)
A0A1P8BFS9_ARATH
832
0
93774
TrEMBL
other Location (Reliability: 1)
A0A1I9LNQ9_ARATH
905
1
102065
TrEMBL
other Location (Reliability: 5)
A0A8F5S1Q2_ARATH
684
0
79224
TrEMBL
other Location (Reliability: 5)
A0A8F5Z890_ARATH
1370
0
155385
TrEMBL
other Location (Reliability: 3)
A0A1B1W4Y1_ARATH
329
0
38137
TrEMBL
Mitochondrion (Reliability: 5)
A0A514YJC9_ARATH
329
0
38153
TrEMBL
Mitochondrion (Reliability: 5)
Q9TJZ1_ARATH
155
0
18123
TrEMBL
Secretory Pathway (Reliability: 5)
Q3ZVA8_ARATH
59
0
6628
TrEMBL
other Location (Reliability: 2)
Q0WWN0_ARATH
786
0
89024
TrEMBL
Chloroplast (Reliability: 1)
A0A7G2ELJ4_ARATH
939
1
105624
TrEMBL
other Location (Reliability: 2)
A0A5S9X5L0_ARATH
1982
0
218900
TrEMBL
other Location (Reliability: 2)
A0A654FB09_ARATH
1980
0
218665
TrEMBL
other Location (Reliability: 2)
A0A1B1W4T9_ARATH
1072
0
121059
TrEMBL
other Location (Reliability: 2)
A0A514YJ81_ARATH
1376
0
156305
TrEMBL
other Location (Reliability: 3)
A0A7G2FA94_ARATH
1640
0
184552
TrEMBL
other Location (Reliability: 3)
A0A178WGI4_ARATH
1453
0
162402
TrEMBL
other Location (Reliability: 2)
A0A178VWE9_ARATH
1768
0
195284
TrEMBL
other Location (Reliability: 2)
A0A654FB18_ARATH
1172
0
132688
TrEMBL
other Location (Reliability: 2)
A0A178UAN7_ARATH
972
0
110216
TrEMBL
Chloroplast (Reliability: 4)
A0A7G2ES14_ARATH
1932
0
216765
TrEMBL
other Location (Reliability: 2)
A0A178W5B4_ARATH
1178
0
132381
TrEMBL
other Location (Reliability: 1)
F4I0I3_ARATH
983
0
111763
TrEMBL
Mitochondrion (Reliability: 2)
A0A7G2E547_ARATH
976
0
110837
TrEMBL
Mitochondrion (Reliability: 3)
A0A178W0J6_ARATH
1078
0
121705
TrEMBL
other Location (Reliability: 2)
A0A178UEB4_ARATH
1161
0
130212
TrEMBL
other Location (Reliability: 1)
A0A7G2E8K7_ARATH
1191
0
134853
TrEMBL
Chloroplast (Reliability: 1)
A0A514YIZ8_ARATH
1376
0
156373
TrEMBL
other Location (Reliability: 3)
A0A5S9X0T4_ARATH
993
0
112624
TrEMBL
Chloroplast (Reliability: 1)
A0A5S9XFF1_ARATH
1172
1
132710
TrEMBL
other Location (Reliability: 2)
A0A654EP02_ARATH
976
0
110879
TrEMBL
Mitochondrion (Reliability: 2)
A0A1B1W4T2_ARATH
1376
0
156339
TrEMBL
other Location (Reliability: 3)
Q3ZVA7_ARATH
254
0
28797
TrEMBL
other Location (Reliability: 3)
A0A654FDM1_ARATH
1134
0
127983
TrEMBL
other Location (Reliability: 2)
A0A5S9XD84_ARATH
1144
0
129152
TrEMBL
other Location (Reliability: 2)
A0A7G2E218_ARATH
1408
0
157828
TrEMBL
other Location (Reliability: 2)
Q3ZVA9_ARATH
267
0
30253
TrEMBL
other Location (Reliability: 3)
A0A178W214_ARATH
960
0
108655
TrEMBL
Chloroplast (Reliability: 1)
A0A5S9WF57_ARATH
1161
0
130403
TrEMBL
other Location (Reliability: 2)
A0A5S9WRP9_ARATH
1461
0
163491
TrEMBL
other Location (Reliability: 3)
A0A654EQM9_ARATH
1453
0
162416
TrEMBL
other Location (Reliability: 2)
A0A5S9WQX5_ARATH
976
0
110930
TrEMBL
Mitochondrion (Reliability: 2)
A0A1I9LNQ8_ARATH
894
1
100536
TrEMBL
other Location (Reliability: 5)
A0A178UF03_ARATH
1376
0
153020
TrEMBL
other Location (Reliability: 2)
Q67XZ1_ARATH
124
0
14586
TrEMBL
other Location (Reliability: 1)
F4INQ5_ARATH
895
0
101286
TrEMBL
Chloroplast (Reliability: 1)
PDB
SCOP
CATH
UNIPROT
ORGANISM
EXTERNAL LINKS (specific for EC-Number 2.7.7.6)
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