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Abortion, Spontaneous
Proteomic analysis on the alteration of protein expression in the placental villous tissue of early pregnancy loss.
Acquired Immunodeficiency Syndrome
1H, 13C, and 15N backbone chemical shift assignments of coronavirus-2 non-structural protein Nsp10.
Acquired Immunodeficiency Syndrome
Crystal structure of the RNA-dependent RNA polymerase from influenza C virus.
Acquired Immunodeficiency Syndrome
Expression of human immunodeficiency virus type 1 (HIV-1) gag, pol, and env proteins from chimeric HIV-1-poliovirus minireplicons.
Acquired Immunodeficiency Syndrome
Finding, Conducting, and Nurturing Science: A Virologist's Memoir.
Acquired Immunodeficiency Syndrome
Identification of SARS-CoV-2 inhibitors from extracts of Houttuynia cordata Thunb.
Acquired Immunodeficiency Syndrome
Improvement of sensitivity and selectivity of high-performance liquid chromatography for anti-retroviral drugs (non-reverse transcriptase inhibitors) by diamond-electrode electrochemical and fluorescence detection.
Acquired Immunodeficiency Syndrome
Interactions and Localization of Escherichia coli Error-Prone DNA Polymerase IV after DNA Damage.
Acquired Immunodeficiency Syndrome
Introduction and immunopathogenesis of acquired immune deficiency syndrome.
Acquired Immunodeficiency Syndrome
Involvement of protein acetylation in glucose-induced transcription of a stress-responsive promoter.
Acquired Immunodeficiency Syndrome
Longitudinal analysis of human immunodeficiency virus type 1-specific cytotoxic T lymphocyte responses: a predominant gag-specific response is associated with nonprogressive infection.
Acquired Immunodeficiency Syndrome
Modifications of chromatin structure in control of gene expression.
Acquired Immunodeficiency Syndrome
Nus transcription elongation factors and RNase III modulate small ribosome subunit biogenesis in Escherichia coli.
Acquired Immunodeficiency Syndrome
On the early emergence of reverse transcription: theoretical basis and experimental evidence.
Acquired Immunodeficiency Syndrome
On the Statistical Accuracy of Biomarker Assays for HIV Incidence.
Acquired Immunodeficiency Syndrome
Phage-displayed La/SS-B antigen as a diagnostic reagent.
Acquired Immunodeficiency Syndrome
Prevalence and Virologic Consequences of Transmitted HIV-1 Drug Resistance in Uganda.
Acquired Immunodeficiency Syndrome
Problems posed by natural environments for monitoring microorganisms.
Acquired Immunodeficiency Syndrome
RNA Polymerase Clamp Movement Aids Dissociation from DNA but Is Not Required for RNA Release at Intrinsic Terminators.
Acquired Immunodeficiency Syndrome
Structural mechanisms of HIV drug resistance.
Acquired Immunodeficiency Syndrome
Suramin inhibits tumor cell cytotoxicity mediated through natural killer cells, lymphokine-activated killer cells, monocytes, and tumor necrosis factor.
Acquired Immunodeficiency Syndrome
Synthetic peptides for AIDS research.
Acquired Immunodeficiency Syndrome
The Current Recommended Drugs and Strategies for the Treatment of Coronavirus Disease (COVID-19).
Acquired Immunodeficiency Syndrome
When machines get stuck--obstructed RNA polymerase II: displacement, degradation or suicide.
Acquired Immunodeficiency Syndrome
[Therapeutic potential of Ro 5-3335. New active benzodiazepine in vitro against HIV-1 viruses resistant or non-resistant to AZT]
Acromegaly
The clinical response to somatostatin analogues in acromegaly correlates to the somatostatin receptor subtype 2a protein expression of the adenoma.
Acute Kidney Injury
Renal failure due to scleroderma with thrombotic microangiopathy developing in a woman treated with carboplatin for ovarian cancer.
Acute Lung Injury
Cold-inducible RNA-binding protein (CIRP) causes sepsis-associated acute lung injury via induction of endoplasmic reticulum stress.
Acute Lung Injury
Emodin Alleviates Severe Acute Pancreatitis-Associated Acute Lung Injury by Inhibiting the Cold-Inducible RNA-Binding Protein (CIRP)-Mediated Activation of the NLRP3/IL-1?/CXCL1 Signaling.
Acute Lung Injury
Extracellular CIRP Induces Inflammation in Alveolar Type II Cells via TREM-1.
Acute Lung Injury
Inhibition of a triggering receptor expressed on myeloid cells-1 (TREM-1) with an extracellular cold-inducible RNA-binding protein (eCIRP)-derived peptide protects mice from intestinal ischemia-reperfusion injury.
Acute Lung Injury
Lung transcriptome of a COVID-19 patient and systems biology predictions suggest impaired surfactant production which may be druggable by surfactant therapy.
Acute Lung Injury
Nonstructural Protein 1 (NS1)-Mediated Inhibition of c-Abl Results in Acute Lung Injury and Priming for Bacterial Coninfections: Insights Into 1918 H1N1 Pandemic?
Adenocarcinoma
Diffuse expression of RNA-binding protein IMP3 predicts high-stage lymph node metastasis and poor prognosis in colorectal adenocarcinoma.
Adenocarcinoma
Expression of RNA-binding protein LIN28 in classic gastric hepatoid carcinomas, gastric fetal type gastrointestinal adenocarcinomas, and hepatocellular carcinomas: An immunohistochemical study with comparison to SALL4, alpha-fetoprotein, glypican-3, and Hep Par1.
Adenocarcinoma
Radiation Sensitivity of Esophageal Adenocarcinoma: The Contribution of the RNA-Binding Protein RNPC1 and p21-Mediated Cell Cycle Arrest to Radioresistance.
Adenocarcinoma
The RNA-binding protein MEX3A is a prognostic factor and regulator of resistance to gemcitabine in pancreatic ductal adenocarcinoma.
Adenocarcinoma of Lung
A gene mutation in RNA-binding protein 10 is associated with lung adenocarcinoma progression and poor prognosis.
Adenocarcinoma of Lung
Development and validation of a prediction model for lung adenocarcinoma based on RNA-binding protein.
Adenocarcinoma of Lung
Expression of the RNA-binding protein HuR and its clinical significance in human stage I and II lung adenocarcinoma.
Adenocarcinoma of Lung
Expression profile, clinical significance, and biological function of insulin-like growth factor 2 messenger RNA-binding proteins in non-small cell lung cancer.
Adenocarcinoma of Lung
Hu/elav RNA-binding protein HuR regulates parathyroid hormone related peptide expression in human lung adenocarcinoma cells.
Adenocarcinoma of Lung
Novel mechanisms for osteogenic differentiation of human aortic valve interstitial cells.
Adenocarcinoma of Lung
Predicting the Clinical Outcome of Lung Adenocarcinoma Using a Novel Gene Pair Signature Related to RNA-Binding Protein.
Adenocarcinoma of Lung
The role of RBM10 mutations in the development, treatment, and prognosis of lung adenocarcinoma.
Adenocarcinoma of Lung
[Tristetraprolin inhibits autophagy in cultured lung cancer cells via the nuclear factor-?B pathway].
Adenoma
The clinical response to somatostatin analogues in acromegaly correlates to the somatostatin receptor subtype 2a protein expression of the adenoma.
Adrenocortical Carcinoma
Characterization of atrial-natriuretic-factor-receptor-coupled membrane guanylate cyclase from rat and mouse testes.
Adrenocortical Carcinoma
Long noncoding RNA ASB16-AS1 inhibits adrenocortical carcinoma cell growth by promoting ubiquitination of RNA-binding protein HuR.
African Horse Sickness
A comparison of the nucleotide sequences of cognate NS2 genes of three different orbiviruses.
African Horse Sickness
Characterization of a nonstructural phosphoprotein of two orbiviruses.
African Horse Sickness
Characterization of tubular structures composed of nonstructural protein NS1 of African horsesickness virus expressed in insect cells.
African Horse Sickness
Identification of African horse sickness virus in cell culture using a digoxigenin-labeled RNA probe.
African Horse Sickness
Sequence analysis of the RNA polymerase gene of African horse sickness virus.
African Horse Sickness
The effect of temperature on the in vitro transcriptase reaction of bluetongue virus, epizootic haemorrhagic disease virus and African horsesickness virus.
African Swine Fever
African swine fever virus encodes two genes which share significant homology with the two largest subunits of DNA-dependent RNA polymerases.
African Swine Fever
African Swine Fever Virus pB119L Protein Is a Flavin Adenine Dinucleotide-Linked Sulfhydryl Oxidase.
African Swine Fever
An African swine fever virus gene with a similarity to eukaryotic RNA polymerase subunit 6.
African Swine Fever
The African swine fever virus nonstructural protein pB602L is required for formation of the icosahedral capsid of the virus particle.
Aleutian Mink Disease
Caspase cleavage of the nonstructural protein NS1 mediates replication of Aleutian mink disease parvovirus.
Aleutian Mink Disease
Purification and characterization of the major nonstructural protein (NS-1) of Aleutian mink disease parvovirus.
Aleutian Mink Disease
The abundant R2 mRNA generated by aleutian mink disease parvovirus is tricistronic, encoding NS2, VP1, and VP2.
Alopecia Areata
Clinical Relevance for Serum Cold-Inducible RNA-Binding Protein Level in Alopecia Areata.
Alphavirus Infections
Dephosphorylation of HuR Protein During Alphavirus Infection Is Associated with HuR Relocalization to the Cytoplasm.
Alphavirus Infections
Innovative cancer vaccine strategies based on the identification of tumour-associated antigens.
Alzheimer Disease
A conserved role for the ALS-linked splicing factor SFPQ in repression of pathogenic cryptic last exons.
Alzheimer Disease
A single N-terminal phosphomimic disrupts TDP-43 polymerization, phase separation, and RNA splicing.
Alzheimer Disease
An optimized InCell Western screening technique identifies hexachlorophene as a novel potent TDP43 targeting drug.
Alzheimer Disease
Association Between Common Variants in RBFOX1, an RNA-Binding Protein, and Brain Amyloidosis in Early and Preclinical Alzheimer Disease.
Alzheimer Disease
Biomolecular condensation of the microtubule-associated protein tau.
Alzheimer Disease
Cdc37/Hsp90 protein complex disruption triggers an autophagic clearance cascade for TDP-43 protein.
Alzheimer Disease
Formation of Toxic Oligomeric Assemblies of RNA-binding Protein: Musashi in Alzheimer's disease.
Alzheimer Disease
Lack of association between TDP-43 pathology and tau mis-splicing in Alzheimer's disease.
Alzheimer Disease
Low-complexity domain of U1-70K modulates phase separation and aggregation through distinctive basic-acidic motifs.
Alzheimer Disease
Myo-granules Connect Physiology and Pathophysiology.
Alzheimer Disease
Preferential Binding of a stable G3BP Ribonucleoprotein Complex to Intron-retaining Transcripts in Mouse Brain and Modulation of their Expression in the Cerebellum.
Alzheimer Disease
PRO-MINE: A Bioinformatics Repository and Analytical Tool for TARDBP Mutations.
Amyloidosis
AFM study of Escherichia coli RNA polymerase ?(70) subunit aggregation.
Amyloidosis
Association Between Common Variants in RBFOX1, an RNA-Binding Protein, and Brain Amyloidosis in Early and Preclinical Alzheimer Disease.
Amyotrophic Lateral Sclerosis
3'UTR Length-Dependent Control of SynGAP Isoform ?2 mRNA by FUS and ELAV-like Proteins Promotes Dendritic Spine Maturation and Cognitive Function.
Amyotrophic Lateral Sclerosis
A conserved role for the ALS-linked splicing factor SFPQ in repression of pathogenic cryptic last exons.
Amyotrophic Lateral Sclerosis
A matter of balance.
Amyotrophic Lateral Sclerosis
A single N-terminal phosphomimic disrupts TDP-43 polymerization, phase separation, and RNA splicing.
Amyotrophic Lateral Sclerosis
Aberrant interaction of FUS with the U1 snRNA provides a molecular mechanism of FUS induced amyotrophic lateral sclerosis.
Amyotrophic Lateral Sclerosis
Abnormal RNA stability in amyotrophic lateral sclerosis.
Amyotrophic Lateral Sclerosis
Activity-dependent FUS dysregulation disrupts synaptic homeostasis.
Amyotrophic Lateral Sclerosis
ALS mutant FUS proteins are recruited into stress granules in induced pluripotent stem cell-derived motoneurons.
Amyotrophic Lateral Sclerosis
ALS Mutations Disrupt Phase Separation Mediated by ?-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain.
Amyotrophic Lateral Sclerosis
ALS-causative mutations in FUS/TLS confer gain and loss of function by altered association with SMN and U1-snRNP.
Amyotrophic Lateral Sclerosis
ALS-implicated protein TDP-43 sustains levels of STMN2, a mediator of motor neuron growth and repair.
Amyotrophic Lateral Sclerosis
ALS-Linked Mutations Enlarge TDP-43-Enriched Neuronal RNA Granules in the Dendritic Arbor.
Amyotrophic Lateral Sclerosis
ALS-related FUS mutations alter axon growth in motoneurons and affect HuD/ELAVL4 and FMRP activity.
Amyotrophic Lateral Sclerosis
ALS/FTLD-Linked Mutations in FUS Glycine Residues Cause Accelerated Gelation and Reduced Interactions with Wild-Type FUS.
Amyotrophic Lateral Sclerosis
Amyotrophic lateral sclerosis-linked mutations increase the viscosity of liquid-like TDP-43 RNP granules in neurons.
Amyotrophic Lateral Sclerosis
An ALS-associated mutation in the FUS 3'-UTR disrupts a microRNA-FUS regulatory circuitry.
Amyotrophic Lateral Sclerosis
An Amyloid-Like Pathological Conformation of TDP-43 Is Stabilized by Hypercooperative Hydrogen Bonds.
Amyotrophic Lateral Sclerosis
An optimized InCell Western screening technique identifies hexachlorophene as a novel potent TDP43 targeting drug.
Amyotrophic Lateral Sclerosis
Ataxin-2: From RNA Control to Human Health and Disease.
Amyotrophic Lateral Sclerosis
Autosomal dominant inheritance of rapidly progressive amyotrophic lateral sclerosis due to a truncation mutation in the fused in sarcoma (FUS) gene.
Amyotrophic Lateral Sclerosis
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Amyotrophic Lateral Sclerosis
Cdc37/Hsp90 protein complex disruption triggers an autophagic clearance cascade for TDP-43 protein.
Amyotrophic Lateral Sclerosis
Characteristic Features of FUS Inclusions in Spinal Motor Neurons of Sporadic Amyotrophic Lateral Sclerosis.
Amyotrophic Lateral Sclerosis
Characterizing the RNA targets and position-dependent splicing regulation by TDP-43.
Amyotrophic Lateral Sclerosis
Cytoplasmic FUS triggers early behavioral alterations linked to cortical neuronal hyperactivity and inhibitory synaptic defects.
Amyotrophic Lateral Sclerosis
Cytoplasmic sequestration of FUS/TLS associated with ALS alters histone marks through loss of nuclear protein arginine methyltransferase 1.
Amyotrophic Lateral Sclerosis
DCTN1 Binds to TDP-43 and Regulates TDP-43 Aggregation.
Amyotrophic Lateral Sclerosis
Detection of TAR DNA-binding protein 43 (TDP-43) oligomers as initial intermediate species during aggregate formation.
Amyotrophic Lateral Sclerosis
Development of a mouse monoclonal antibody for the detection of asymmetric dimethylarginine of Translocated in LipoSarcoma/FUsed in Sarcoma and its application in analyzing methylated TLS.
Amyotrophic Lateral Sclerosis
Differential toxicity of TAR DNA-binding protein 43 isoforms depends on their submitochondrial localization in neuronal cells.
Amyotrophic Lateral Sclerosis
Distinct and shared functions of ALS-associated proteins TDP-43, FUS and TAF15 revealed by multisystem analyses.
Amyotrophic Lateral Sclerosis
Dysregulated miRNA biogenesis downstream of cellular stress and ALS-causing mutations: a new mechanism for ALS.
Amyotrophic Lateral Sclerosis
Exploring the Interaction of
Amyotrophic Lateral Sclerosis
Expression of Fused in sarcoma mutations in mice recapitulates the neuropathology of FUS proteinopathies and provides insight into disease pathogenesis.
Amyotrophic Lateral Sclerosis
Frontotemporal dementia and amyotrophic lateral sclerosis-associated disease protein TDP-43 promotes dendritic branching.
Amyotrophic Lateral Sclerosis
Functional and dynamic polymerization of the ALS-linked protein TDP-43 antagonizes its pathologic aggregation.
Amyotrophic Lateral Sclerosis
Functional characterization of a FUS mutant zebrafish line as a novel genetic model for ALS.
Amyotrophic Lateral Sclerosis
FUS affects circular RNA expression in murine embryonic stem cell-derived motor neurons.
Amyotrophic Lateral Sclerosis
FUS ALS-causative mutations impair FUS autoregulation and splicing factor networks through intron retention.
Amyotrophic Lateral Sclerosis
FUS binds the CTD of RNA polymerase II and regulates its phosphorylation at Ser2.
Amyotrophic Lateral Sclerosis
FUS contributes to mTOR-dependent inhibition of translation.
Amyotrophic Lateral Sclerosis
FUS is sequestered in nuclear aggregates in ALS patient fibroblasts.
Amyotrophic Lateral Sclerosis
FUS Regulates Activity of MicroRNA-Mediated Gene Silencing.
Amyotrophic Lateral Sclerosis
FUS regulates genes coding for RNA-binding proteins in neurons by binding to their highly conserved introns.
Amyotrophic Lateral Sclerosis
FUS/TLS deficiency causes behavioral and pathological abnormalities distinct from amyotrophic lateral sclerosis.
Amyotrophic Lateral Sclerosis
Futsch/MAP1B mRNA is a translational target of TDP-43 and is neuroprotective in a Drosophila model of amyotrophic lateral sclerosis.
Amyotrophic Lateral Sclerosis
HDAC6 is a Bruchpilot deacetylase that facilitates neurotransmitter release.
Amyotrophic Lateral Sclerosis
High-content RNAi screening identifies the Type 1 inositol triphosphate receptor as a modifier of TDP-43 localization and neurotoxicity.
Amyotrophic Lateral Sclerosis
Hu antigen R (HuR) is a positive regulator of the RNA-binding proteins TDP-43 and FUS/TLS: implications for amyotrophic lateral sclerosis.
Amyotrophic Lateral Sclerosis
Hypertonic Stress Causes Cytoplasmic Translocation of Neuronal, but Not Astrocytic, FUS due to Impaired Transportin Function.
Amyotrophic Lateral Sclerosis
Identification of Genetic Modifiers of TDP-43 Neurotoxicity in Drosophila.
Amyotrophic Lateral Sclerosis
Inter-Species Differences in Regulation of the Progranulin-Sortilin Axis in TDP-43 Cell Models of Neurodegeneration.
Amyotrophic Lateral Sclerosis
Intrinsic disorder in proteins involved in amyotrophic lateral sclerosis.
Amyotrophic Lateral Sclerosis
Loss of Dynamic RNA Interaction and Aberrant Phase Separation Induced by Two Distinct Types of ALS/FTD-Linked FUS Mutations.
Amyotrophic Lateral Sclerosis
Loss of Tdp-43 disrupts the axonal transcriptome of motoneurons accompanied by impaired axonal translation and mitochondria function.
Amyotrophic Lateral Sclerosis
Low Level of Expression of C-Terminally Truncated Human FUS Causes Extensive Changes in the Spinal Cord Transcriptome of Asymptomatic Transgenic Mice.
Amyotrophic Lateral Sclerosis
Mechanisms of TDP-43 Proteinopathy Onset and Propagation.
Amyotrophic Lateral Sclerosis
Mislocalisation of TDP-43 to the cytoplasm causes cortical hyperexcitability and reduced excitatory neurotransmission in the motor cortex.
Amyotrophic Lateral Sclerosis
Molecular Dissection of FUS Points at Synergistic Effect of Low-Complexity Domains in Toxicity.
Amyotrophic Lateral Sclerosis
Molecular structure and interactions within amyloid-like fibrils formed by a low-complexity protein sequence from FUS.
Amyotrophic Lateral Sclerosis
Motor neuron expression of the voltage-gated calcium channel cacophony restores locomotion defects in a Drosophila, TDP-43 loss of function model of ALS.
Amyotrophic Lateral Sclerosis
Mutant FUS proteins that cause amyotrophic lateral sclerosis incorporate into stress granules.
Amyotrophic Lateral Sclerosis
Myo-granules Connect Physiology and Pathophysiology.
Amyotrophic Lateral Sclerosis
N-terminal acetylation modestly enhances phase separation and reduces aggregation of the low-complexity domain of RNA-binding protein fused in sarcoma.
Amyotrophic Lateral Sclerosis
Neuron-to-Neuron Transfer of FUS in Drosophila Primary Neuronal Culture Is Enhanced by ALS-Associated Mutations.
Amyotrophic Lateral Sclerosis
Neurotoxic effects of TDP-43 overexpression in C. elegans.
Amyotrophic Lateral Sclerosis
Post-transcriptional Inhibition of Hsc70-4/HSPA8 Expression Leads to Synaptic Vesicle Cycling Defects in Multiple Models of ALS.
Amyotrophic Lateral Sclerosis
PRO-MINE: A Bioinformatics Repository and Analytical Tool for TARDBP Mutations.
Amyotrophic Lateral Sclerosis
Proteomic Analysis of Dynein-Interacting Proteins in Amyotrophic Lateral Sclerosis Synaptosomes Reveals Alterations in the RNA-Binding Protein Staufen1.
Amyotrophic Lateral Sclerosis
Quantitative analysis of cryptic splicing associated with TDP-43 depletion.
Amyotrophic Lateral Sclerosis
Restoration of motor defects caused by loss of Drosophila TDP-43 by expression of the voltage-gated calcium channel, Cacophony, in central neurons.
Amyotrophic Lateral Sclerosis
RNA-binding proteins in neurodegenerative disease: TDP-43 and beyond.
Amyotrophic Lateral Sclerosis
S-nitrosylated TDP-43 triggers aggregation, cell-to-cell spread, and neurotoxicity in hiPSCs and in vivo models of ALS/FTD.
Amyotrophic Lateral Sclerosis
Severe respiratory changes at end stage in a FUS-induced disease state in adult rats.
Amyotrophic Lateral Sclerosis
Shortened TDP43 isoforms upregulated by neuronal hyperactivity drive TDP43 pathology in ALS.
Amyotrophic Lateral Sclerosis
Single-copy expression of an amyotrophic lateral sclerosis-linked TDP-43 mutation (M337V) in BAC transgenic mice leads to altered stress granule dynamics and progressive motor dysfunction.
Amyotrophic Lateral Sclerosis
Specific aromatic foldamers potently inhibit spontaneous and seeded A?42 and A?43 fibril assembly.
Amyotrophic Lateral Sclerosis
Split GFP technologies to structurally characterize and quantify functional biomolecular interactions of FTD-related proteins.
Amyotrophic Lateral Sclerosis
Structural analysis of disease-related TDP-43 D169G mutation: linking enhanced stability and caspase cleavage efficiency to protein accumulation.
Amyotrophic Lateral Sclerosis
Structural basis for RNA recognition by the N-terminal tandem RRM domains of human RBM45.
Amyotrophic Lateral Sclerosis
SUMOylation Regulates TDP-43 Splicing Activity and Nucleocytoplasmic Distribution.
Amyotrophic Lateral Sclerosis
Synaptic FUS accumulation triggers early misregulation of synaptic RNAs in a mouse model of ALS.
Amyotrophic Lateral Sclerosis
TBPH/TDP-43 modulates translation of Drosophila futsch mRNA through an UG-rich sequence within its 5'UTR.
Amyotrophic Lateral Sclerosis
TDP-43 ?-helical structure tunes liquid-liquid phase separation and function.
Amyotrophic Lateral Sclerosis
TDP-43 accelerates deadenylation of target mRNAs by recruiting Caf1 deadenylase.
Amyotrophic Lateral Sclerosis
TDP-43 and NOVA-1 RNA-binding proteins as competitive splicing regulators of the schizophrenia-associated TNIK gene.
Amyotrophic Lateral Sclerosis
TDP-43 and RNA form amyloid-like myo-granules in regenerating muscle.
Amyotrophic Lateral Sclerosis
TDP-43 controls lysosomal pathways thereby determining its own clearance and cytotoxicity.
Amyotrophic Lateral Sclerosis
TDP-43 mutations causing amyotrophic lateral sclerosis are associated with altered expression of RNA-binding protein hnRNP K and affect the Nrf2 antioxidant pathway.
Amyotrophic Lateral Sclerosis
TDP-43 prevents retrotransposon activation in the Drosophila motor system through regulation of Dicer-2 activity.
Amyotrophic Lateral Sclerosis
TDP-43 proteinopathy in Theiler's murine encephalomyelitis virus infection.
Amyotrophic Lateral Sclerosis
TDP-43 regulates early-phase insulin secretion via CaV1.2-mediated exocytosis in islets.
Amyotrophic Lateral Sclerosis
TDP-43 suppresses CGG repeat-induced neurotoxicity through interactions with HnRNP A2/B1.
Amyotrophic Lateral Sclerosis
TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration.
Amyotrophic Lateral Sclerosis
TDP-43, an ALS Linked Protein, Regulates Fat Deposition and Glucose Homeostasis.
Amyotrophic Lateral Sclerosis
The FTD/ALS-associated RNA-binding protein TDP-43 regulates the robustness of neuronal specification through microRNA-9a in Drosophila.
Amyotrophic Lateral Sclerosis
The Impact of ALS-Associated Genes hnRNPA1, MATR3, VCP and UBQLN2 on the Severity of TDP-43 Aggregation.
Amyotrophic Lateral Sclerosis
The RNA-binding motif 45 (RBM45) protein accumulates in inclusion bodies in amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration with TDP-43 inclusions (FTLD-TDP) patients.
Amyotrophic Lateral Sclerosis
The role of FUS gene variants in neurodegenerative diseases.
Amyotrophic Lateral Sclerosis
Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss.
Amyotrophic Lateral Sclerosis
Translocated in liposarcoma regulates the distribution and function of mammalian enabled, a modulator of actin dynamics.
Amyotrophic Lateral Sclerosis
Transposable Elements in TDP-43-Mediated Neurodegenerative Disorders.
Amyotrophic Lateral Sclerosis
Viral Infections Exacerbate FUS-ALS Phenotypes in iPSC-Derived Spinal Neurons in a Virus Species-Specific Manner.
Amyotrophic Lateral Sclerosis
Wild-type FUS corrects ALS-like disease induced by cytoplasmic mutant FUS through autoregulation.
Anemia
A truncated apoptin protein variant selectively kills cancer cells.
Anemia
Haemolytic anaemia precipitated by dengue fever.
Anemia
Identification of a novel cell-penetrating peptide derived from the capsid protein of chicken anemia virus and its application in gene delivery.
Anemia
Improving the potency of DNA vaccine against Chicken Anemia Virus (CAV) by fusing VP1 protein of CAV to Marek's Disease Virus (MDV) Type-1 VP22 protein.
Anemia
Infectious salmon anemia virus (ISAV) genomic segment 3 encodes the viral nucleoprotein (NP), an RNA-binding protein with two monopartite nuclear localization signals (NLS).
Anemia
Lactobacillus acidophilus as a live vehicle for oral immunization against chicken anemia virus.
Anemia
Silver nanoparticles induced RNA polymerase-silver binding and RNA transcription inhibition in erythroid progenitor cells.
Anemia
Simultaneous expression of recombinant baculovirus-encoded chicken anaemia virus (CAV) proteins VP1 and VP2 is required for formation of the CAV-specific neutralizing epitope.
Anemia, Hemolytic
Effect of phenylhydrazine-induced hemolytic anemia on nuclear RNA polymerase activity of the mouse spleen.
Anemia, Hypochromic
A new method for functional analysis of plastid EMBRYO-DEFECTIVE PPR genes by efficiently constructing cosuppression lines in Arabidopsis.
Aneurysm
Detection of active cytomegalovirus infection in inflammatory aortic aneurysms with RNA polymerase chain reaction.
Anodontia
Endocrine Aspects of 4H Leukodystrophy: A Case Report and Review of the Literature.
Anthrax
Bacillus anthracis Virulence Regulator AtxA Binds Specifically to the pagA Promoter Region.
Antiphospholipid Syndrome
Scleroderma-specific autoantibodies embedded in immune complexes mediate endothelial damage: an early event in the pathogenesis of systemic sclerosis.
Aortic Aneurysm
Detection of active cytomegalovirus infection in inflammatory aortic aneurysms with RNA polymerase chain reaction.
Aortic Aneurysm
Regarding "Detection of active cytomegalovirus infection in inflammatory aortic aneurysms with RNA polymerase chain reaction".
Aortic Aneurysm, Abdominal
Cold-inducible RNA-binding protein plays a central role in the pathogenesis of abdominal aortic aneurysm in a murine experimental model.
Aortic Valve Stenosis
Novel mechanisms for osteogenic differentiation of human aortic valve interstitial cells.
Apraxias
Senataxin, defective in the neurodegenerative disorder ataxia with oculomotor apraxia 2, lies at the interface of transcription and the DNA damage response.
Arbovirus Infections
Arboviruses and the Challenge to Establish Systemic and Persistent Infections in Competent Mosquito Vectors: The Interaction With the RNAi Mechanism.
Arteritis
A zinc finger-containing papain-like protease couples subgenomic mRNA synthesis to genome translation in a positive-stranded RNA virus.
Arteritis
Adaptive Mutations in Replicase Transmembrane Subunits Can Counteract Inhibition of Equine Arteritis Virus RNA Synthesis by Cyclophilin Inhibitors.
Arteritis
Alternative proteolytic processing of the arterivirus replicase ORF1a polyprotein: evidence that NSP2 acts as a cofactor for the NSP4 serine protease.
Arteritis
Arterivirus nsp12 versus the coronavirus nsp16 2'-O-methyltransferase: comparison of the C-terminal cleavage products of two nidovirus pp1ab polyproteins.
Arteritis
Biochemical characterization of the equine arteritis virus helicase suggests a close functional relationship between arterivirus and coronavirus helicases.
Arteritis
Equine arteritis virus does not induce interferon production in equine endothelial cells: identification of nonstructural protein 1 as a main interferon antagonist.
Arteritis
Functional properties of the predicted helicase of porcine reproductive and respiratory syndrome virus.
Arteritis
Lelystad virus, the causative agent of porcine epidemic abortion and respiratory syndrome (PEARS), is related to LDV and EAV.
Arteritis
Molecular Epidemiology and Genetic Characterization of Equine Arteritis Virus Isolates Associated with the 2006/2007 Multi-State Disease Occurrence in the USA.
Arteritis
ORF1a-encoded replicase subunits are involved in the membrane association of the arterivirus replication complex.
Arteritis
Processing of the equine arteritis virus replicase ORF1b protein: identification of cleavage products containing the putative viral polymerase and helicase domains.
Arteritis
Proteolytic processing of the replicase ORF1a protein of equine arteritis virus.
Arteritis
The arterivirus Nsp2 protease. An unusual cysteine protease with primary structure similarities to both papain-like and chymotrypsin-like proteases.
Arteritis
Variability of non-structural proteins of equine arteritis virus during persistent infection of the stallion.
Arthralgia
Antibody to parvovirus B19 nonstructural protein is associated with chronic arthralgia in patients with chronic fatigue syndrome/myalgic encephalomyelitis.
Arthralgia
Haemolytic anaemia precipitated by dengue fever.
Arthritis
A case of macrophage activation syndrome in a patient with anti-synthetase syndrome.
Arthritis
Antisynthetase Syndrome with Anti-Jo1 Antibodies in 48 Patients: Pulmonary Involvement Predicts Disease-modifying Antirheumatic Drug Use.
Arthritis
Clinical features of anti-synthetase syndrome associated interstitial lung disease: a retrospective cohort in China.
Arthritis
Development of antibodies to the nonstructural protein NS1 of parvovirus B19 during acute symptomatic and subclinical infection in pregnancy: implications for pathogenesis doubtful.
Arthritis
Human parvovirus B19 transgenic mice become susceptible to polyarthritis.
Arthritis
Persistence of parvovirus B19 DNA in synovium of patients with haemophilic arthritis.
Arthritis
Recent advances in the role of RNA-binding protein, tristetraprolin, in arthritis.
Arthritis
The Diagnosis and Treatment of Antisynthetase Syndrome.
Arthritis
Viral arthritis.
Arthritis
[Antisynthetase syndrome: a retrospective study of 14 patients].
Arthritis, Rheumatoid
Anti-human parvovirus B19 nonstructural protein antibodies in patients with rheumatoid arthritis.
Arthritis, Rheumatoid
Human parvovirus B19 transgenic mice become susceptible to polyarthritis.
Arthritis, Rheumatoid
Infectious Rice Body Formation in a Patient with Anti-aminoacyl-t RNA Synthetase Syndrome: A Case Report.
Arthritis, Rheumatoid
Sensitivity and specificity of anti-Jo-1 antibodies in autoimmune diseases with myositis.
Arthritis, Rheumatoid
Serum and synovial fluid concentrations of cold-inducible RNA-binding protein in patients with rheumatoid arthritis.
Arthritis, Rheumatoid
Targeting Tristetraprolin Expression or Functional Activity Regulates Inflammatory Response Induced by MSU Crystals.
Arthritis, Rheumatoid
The RNA polymerase I-specific transcription initiation factor UBF is associated with transcriptionally active and inactive ribosomal genes.
Asthma
Theophylline inhibits the production of nitric oxide by peripheral blood mononuclear cells from patients with asthma.
Asymptomatic Infections
Development of antibodies to the nonstructural protein NS1 of parvovirus B19 during acute symptomatic and subclinical infection in pregnancy: implications for pathogenesis doubtful.
Asymptomatic Infections
Suppression of a SARS-CoV-2 outbreak in the Italian municipality of Vo'.
Ataxia
High expression of neuro-oncological ventral antigen 1 correlates with poor prognosis in hepatocellular carcinoma.
Ataxia
Nova-1 regulates neuron-specific alternative splicing and is essential for neuronal viability.
Ataxia
Senataxin, defective in the neurodegenerative disorder ataxia with oculomotor apraxia 2, lies at the interface of transcription and the DNA damage response.
Atherosclerosis
Endothelial HuR deletion reduces the expression of proatherogenic molecules and attenuates atherosclerosis.
Atherosclerosis
Proatherogenic stimuli induce HuR in atherosclerosis through MAPK/ErK pathway.
Atherosclerosis
RNA polymerase and protein kinase activities of aortic nuclei during early atherogenesis.
Atherosclerosis
The Role of PB1 Domain Proteins in Endothelial Cell Dysfunction and Disease.
Atrial Fibrillation
Cold-inducible RNA-binding protein modulates atrial fibrillation onset by targeting multiple ion channels.
Atypical Squamous Cells of the Cervix
Meiotic silencing in the homothallic fungus Gibberella zeae.
Atypical Squamous Cells of the Cervix
Neurospora spore killers Sk-2 and Sk-3 suppress meiotic silencing by unpaired DNA.
Autoimmune Diseases
A case of macrophage activation syndrome in a patient with anti-synthetase syndrome.
Autoimmune Diseases
Arid5a-deficient mice are highly resistant to bleomycin-induced lung injury.
Autoimmune Diseases
Developmental characterization of a Drosophila RNA-binding protein homologous to the human systemic lupus erythematosus-associated La/SS-B autoantigen.
Autoimmune Diseases
Molecular control of Tfh-cell differentiation by Roquin family proteins.
Autoimmune Diseases
Recently characterised autoantibodies and their clinical significance.
Autoimmune Diseases
The roles of hnRNP A2/B1 in RNA biology and disease.
Azoospermia
A novel nucleocytoplasmic shuttling sequence of DAZAP1, a testis-abundant RNA-binding protein.
Azoospermia
A Y chromosome gene family with RNA-binding protein homology: candidates for the azoospermia factor AZF controlling human spermatogenesis.
Azoospermia
Caenorhabditis elegans homologue of the human azoospermia factor DAZ is required for oogenesis but not for spermatogenesis.
Azoospermia
Genomic structure and transcript variants of the bovine DAZL gene.
Azoospermia
Oncogenic Role of BOLL in Colorectal Cancer.
Bacterial Infections
The RNA-binding protein tristetraprolin schedules apoptosis of pathogen-engaged neutrophils during bacterial infection.
Blast Crisis
High levels of the BCR/ABL oncoprotein are required for the MAPK-hnRNP-E2 dependent suppression of C/EBPalpha-driven myeloid differentiation.
Blast Crisis
Regulation of myeloid leukaemia by the cell-fate determinant Musashi.
Blister
Ptbp1 and Exosc9 knockdowns trigger skin stability defects through different pathways.
Bloom Syndrome
BLM helicase facilitates RNA polymerase I-mediated ribosomal RNA transcription.
Bluetongue
A comparison of the nucleotide sequences of cognate NS2 genes of three different orbiviruses.
Bluetongue
A differential ELISA based on recombinant immunodominant epitopes of the gE gene of SHV-1 in a baculovirus-insect cell system to discriminate between pigs infected naturally with pseudorabies and vaccinated pigs.
Bluetongue
Analysis of murine B-cell epitopes on bluetongue virus 12 nonstructural protein 1.
Bluetongue
Assembly of five bluetongue virus proteins expressed by recombinant baculoviruses: inclusion of the largest protein VP1 in the core and virus-like proteins.
Bluetongue
Baculovirus-expressed nonstructural protein NS2 of bluetongue virus induces a cytotoxic T-cell response in mice which affords partial protection.
Bluetongue
Bluetongue virus nonstructural protein NS3/NS3a is not essential for virus replication.
Bluetongue
Bluetongue virus-17 fusion protein ns1 expressed in Escherichia coli by pUC vectors.
Bluetongue
CD8 T Cell Responses to an Immunodominant Epitope within the Nonstructural Protein NS1 Provide Wide Immunoprotection against Bluetongue Virus in IFNAR-/- Mice.
Bluetongue
Characterization of a nonstructural phosphoprotein of two orbiviruses.
Bluetongue
Deletion and mutational analyses of bluetongue virus NS2 protein indicate that the amino but not the carboxy terminus of the protein is critical for RNA-protein interactions.
Bluetongue
Evidence for genetic relationship between RNA and DNA viruses from the sequence homology of a putative polymerase gene of bluetongue virus with that of vaccinia virus: conservation of RNA polymerase genes from diverse species.
Bluetongue
Expression of a full-length nonstructural protein NS1 of bluetongue virus serotype 17 in Escherichia coli.
Bluetongue
Expression of largest RNA segment and synthesis of VP1 protein of bluetongue virus in insect cells by recombinant baculovirus: association of VP1 protein with RNA polymerase activity.
Bluetongue
In situ structures of RNA-dependent RNA polymerase inside bluetongue virus before and after uncoating.
Bluetongue
In vitro phosphorylation and purification of a nonstructural protein of bluetongue virus with affinity for single-stranded RNA.
Bluetongue
Localization of the nonstructural protein NS1 in bluetongue virus-infected cells and its presence in virus particles.
Bluetongue
Localization of the single-stranded RNA-binding domains of bluetongue virus nonstructural protein NS2.
Bluetongue
Multimers of the bluetongue virus nonstructural protein, NS2, possess nucleotidyl phosphatase activity: similarities between NS2 and rotavirus NSP2.
Bluetongue
Mutation of either of two cysteine residues or deletion of the amino or carboxy terminus of nonstructural protein NS1 of bluetongue virus abrogates virus-specified tubule formation in insect cells.
Bluetongue
Nucleotide and deduced amino acid sequence of the nonstructural phosphoprotein, NS2, of bluetongue virus serotype 17: comparison to two isolates of serotype 10.
Bluetongue
Nucleotide and deduced amino acid sequence of the nonstructural protein, NS1, of the US bluetongue virus serotype 17.
Bluetongue
Nucleotide sequence of the genome segment encoding nonstructural protein NS1 of bluetongue virus serotype 20 from Australia.
Bluetongue
Primer-independent RNA sequencing with bacteriophage phi6 RNA polymerase and chain terminators.
Bluetongue
Purified recombinant bluetongue virus VP1 exhibits RNA replicase activity.
Bluetongue
Release of bluetongue virus-like particles from insect cells is mediated by BTV nonstructural protein NS3/NS3A.
Bluetongue
Sequence analyses and antigenic epitope mapping of the putative RNA-directed RNA polymerase of five U.S. bluetongue viruses.
Bluetongue
Specific binding of Bluetongue virus NS2 to different viral plus-strand RNAs.
Bluetongue
The complete sequence of genome segment 8 of bluetongue virus, serotype 1, which encodes the nonstructural protein, NS2.
Bluetongue
The effect of temperature on the in vitro transcriptase reaction of bluetongue virus, epizootic haemorrhagic disease virus and African horsesickness virus.
Bluetongue
The identification of factors capable of reversing the core-mediated inhibition of the bluetongue virus transcriptase.
Bluetongue
The in vitro activation and further characterization of the bluetongue virus-associated transcriptase.
Bluetongue
Virus-derived tubular structure displaying foreign sequences on the surface elicit CD4+ Th cell and protective humoral responses.
Bone Resorption
Inhibition of Osteoclastogenesis by the RNA-Binding Protein QKI5: a Novel Approach to Protect from Bone Resorption.
Borna Disease
Evidence for translation of the Borna disease virus G protein by leaky ribosomal scanning and ribosomal reinitiation.
Borna Disease
Functional characterization of the major and minor phosphorylation sites of the P protein of Borna disease virus.
Borna Disease
RNA polymerase II-controlled expression of antigenomic RNA enhances the rescue efficacies of two different members of the Mononegavirales independently of the site of viral genome replication.
Borna Disease
The Borna disease virus (BoDV) 2 nucleoprotein is a conspecific protein that enhances BoDV-1 RNA-dependent RNA polymerase activity.
Brain Injuries
Association between CIRP expression and hypoxic-ischemic brain injury in neonatal rats.
Brain Injuries
Cold-inducible RNA-binding protein contributes to intracerebral hemorrhage-induced brain injury via TLR4 signaling.
Brain Injuries, Traumatic
Neuroprotective effects of cold-inducible RNA-binding protein during mild hypothermia on traumatic brain injury.
Brain Ischemia
Cold-inducible RNA-binding protein mediates neuroinflammation in cerebral ischemia.
Brain Ischemia
Effects of hypothermia and cerebral ischemia on cold-inducible RNA-binding protein mRNA expression in rat brain.
Brain Ischemia
Musashi1 as a marker of reactive astrocytes after transient focal brain ischemia.
Brain Ischemia
The Value of Extracellular Cold-Inducible RNA-Binding Protein (eCIRP) in Predicting the Severity and Prognosis of Patients After Cardiac Arrest: A Preliminary Observational Study.
Brain Neoplasms
A Novel Mutation in Brain Tumor Causes Both Neural Over-Proliferation and Neurodegeneration in Adult Drosophila.
Brain Neoplasms
Brain tumor is a sequence-specific RNA-binding protein that directs maternal mRNA clearance during the Drosophila maternal-to-zygotic transition.
Brain Neoplasms
Cold-inducible RNA-binding protein (CIRBP) as a biomarker to predict recurrence of brain metastases.
Brain Neoplasms
Expression of the Neural RNA-binding protein Musashi1 in pediatric brain tumors.
Brain Neoplasms
Invasive growth associated with Cold-Inducible RNA-Binding Protein expression drives recurrence of surgically resected brain metastases.
Brain Neoplasms
Multilayered gene control drives timely exit from the stem cell state in uncommitted progenitors during Drosophila asymmetric neural stem cell division.
Brain Neoplasms
Properties of RNA polymerase from a transplantable brain tumor.
Brain Neoplasms
RNA polymerase activity in homotransplanted rat brain tumors initially induced by ethylnitrosourea.
Brain Neoplasms
RNA polymerase activity in human brain tumors.
Brain Neoplasms
The tumour suppressor brain tumour (Brat) regulates linker histone dBigH1 expression in the Drosophila female germline and the early embryo.
Breast Neoplasms
Cell type-restricted activity of hnRNPM promotes breast cancer metastasis via regulating alternative splicing.
Breast Neoplasms
Circular RNA La-related RNA-binding protein 4 correlates with reduced tumor stage, as well as better prognosis, and promotes chemosensitivity to doxorubicin in breast cancer.
Breast Neoplasms
Clinicopathological Significance of TARBP2, APP, and ZNF395 in Breast Cancer.
Breast Neoplasms
Cold-inducible RNA-binding protein contributes to human antigen R and cyclin E1 deregulation in breast cancer.
Breast Neoplasms
Collagen-induced differential expression of an RNA polymerase subunit by breast cancer cells.
Breast Neoplasms
Correction: Musashi RNA-binding protein 2 regulates estrogen receptor 1 function in breast cancer.
Breast Neoplasms
Double-stranded RNA-binding protein regulates vascular endothelial growth factor mRNA stability, translation, and breast cancer angiogenesis.
Breast Neoplasms
EMP3 negatively modulates breast cancer cell DNA replication, DNA damage repair, and stem-like properties.
Breast Neoplasms
Endogenous tRNA-Derived Fragments Suppress Breast Cancer Progression via YBX1 Displacement.
Breast Neoplasms
Epigenetic inactivation of the splicing RNA-binding protein CELF2 in human breast cancer.
Breast Neoplasms
Expression of the RNA-binding protein RBM3 is associated with a favourable prognosis and cisplatin sensitivity in epithelial ovarian cancer.
Breast Neoplasms
Functional analysis of an alternatively spliced estrogen receptor lacking exon 4 isolated from MCF-7 breast cancer cells and meningioma tissue.
Breast Neoplasms
Genistein suppresses the invasive potential of human breast cancer cells through transcriptional regulation of metalloproteinases and their tissue inhibitors.
Breast Neoplasms
High RBM3 expression in prostate cancer independently predicts a reduced risk of biochemical recurrence and disease progression.
Breast Neoplasms
HuR and the bioenergetic signature of breast cancer: a low tumor expression of the RNA-binding protein predicts a higher risk of disease recurrence.
Breast Neoplasms
Integrated Regulation of HuR by Translation Repression and Protein Degradation Determines Pulsatile Expression of p53 Under DNA Damage.
Breast Neoplasms
Loss of the multifunctional RNA-binding protein RBM47 as a source of selectable metastatic traits in breast cancer.
Breast Neoplasms
Mammary epithelial morphogenesis and early breast cancer. Evidence of involvement of basal components of the RNA Polymerase I transcription machinery.
Breast Neoplasms
MiR-421 promotes the development of osteosarcoma by regulating MCPIP1 expression.
Breast Neoplasms
Msi1 promotes breast cancer metastasis by regulating invadopodia-mediated extracellular matrix degradation via the Timp3-Mmp9 pathway.
Breast Neoplasms
Musashi RNA-binding protein 2 regulates estrogen receptor 1 function in breast cancer.
Breast Neoplasms
Nuclear expression of the RNA-binding protein RBM3 is associated with an improved clinical outcome in breast cancer.
Breast Neoplasms
Pharmacogenetics of the anti-HCV drug sofosbuvir: a preliminary study.
Breast Neoplasms
PSF Promotes ER-Positive Breast Cancer Progression via Posttranscriptional Regulation of ESR1 and SCFD2.
Breast Neoplasms
PTEN expression is upregulated by a RNA-binding protein RBM38 via enhancing its mRNA stability in breast cancer.
Breast Neoplasms
Regulation of Mcl-1 by SRSF1 and SRSF5 in cancer cells.
Breast Neoplasms
RNA-binding protein CELF2 inhibits breast cancer cell invasion and angiogenesis by downregulating NFATc1.
Breast Neoplasms
RNA-binding protein CUGBP1 controls the differential INSR splicing in molecular subtypes of breast cancer cells and affects cell aggressiveness.
Breast Neoplasms
RNA-Binding Protein Dnd1 Promotes Breast Cancer Apoptosis by Stabilizing the Bim mRNA in a miR-221 Binding Site.
Breast Neoplasms
RNA-binding protein NONO promotes breast cancer proliferation by post-transcriptional regulation of SKP2 and E2F8.
Breast Neoplasms
RNA-binding protein QKI suppresses breast cancer via RASA1/MAPK signaling pathway.
Breast Neoplasms
RNA-binding protein RNPC1: acting as a tumor suppressor in breast cancer.
Breast Neoplasms
RNA-binding protein SAMD4A inhibits breast tumor angiogenesis by modulating the balance of angiogenesis program.
Breast Neoplasms
RNPC1 enhances progesterone receptor functions by regulating its mRNA stability in breast cancer.
Breast Neoplasms
Sam68 Mediates the Activation of Insulin and Leptin Signalling in Breast Cancer Cells.
Breast Neoplasms
Sam68 up-regulation correlates with, and its down-regulation inhibits, proliferation and tumourigenicity of breast cancer cells.
Breast Neoplasms
Tamoxifen represses alcohol-induced transcription of RNA polymerase III-dependent genes in breast cancer cells.
Breast Neoplasms
Targeting the interaction between RNA-binding protein HuR and FOXQ1 suppresses breast cancer invasion and metastasis.
Breast Neoplasms
The androgen receptor mRNA.
Breast Neoplasms
The RNA-binding protein HuR regulates GATA3 mRNA stability in human breast cancer cell lines.
Breast Neoplasms
The RNA-binding protein Musashi 1 stabilizes the oncotachykinin 1 mRNA in breast cancer cells to promote cell growth.
Breast Neoplasms
The RNA-binding protein RBPMS1 represses AP-1 signaling and regulates breast cancer cell proliferation and migration.
Breast Neoplasms
Transcriptional features of fractionated human breast tumor chromatin.
Breast Neoplasms
[Relationship between expression of RBM38 and distant metastasis and prognosis of breast cancer].
Bronchiolitis
Molecular mechanisms of respiratory syncytial virus replication: a guide for the development of antivirals.
Bronchitis
Comparative analysis of complete genome sequences of three avian coronaviruses reveals a novel group 3c coronavirus.
Bronchitis
Complete sequence (20 kilobases) of the polyprotein-encoding gene 1 of transmissible gastroenteritis virus.
Bronchitis
Coronavirus infectious bronchitis virus non-structural proteins 8 and 12 form stable complex independent of the non-translated regions of viral RNA and other viral proteins.
Bronchitis
Coronavirus NSP6 restricts autophagosome expansion.
Bronchitis
Crystallization and preliminary X-ray diffraction studies of infectious bronchitis virus nonstructural protein 9.
Bronchitis
Kidney Cell-Adapted Infectious Bronchitis ArkDPI Vaccine is Stable and Protective.
Bronchitis
Kidney Cell-Adapted Infectious Bronchitis Virus Arkansas Delmarva Poultry Industry Vaccine Confers Effective Protection Against Challenge.
Bronchitis
Molecular characterization of infectious bronchitis virus based on RNA-dependent RNA polymerase gene.
Bronchitis
Nucleotide sequence of the E2-peplomer protein gene and partial nucleotide sequence of the upstream polymerase gene of transmissible gas gastroenteritis virus (Miller strain).
Bronchitis
Nucleotide sequence of the human coronavirus 229E RNA polymerase locus.
Bronchitis
Proteolytic processing of the polyprotein encoded by ORF1b of the coronavirus infectious bronchitis virus (IBV).
Bronchitis
Purification, crystallization and preliminary X-ray analysis of nonstructural protein 2 (nsp2) from avian infectious bronchitis virus.
Bronchitis
Reverse transcription loop-mediated isothermal amplification for the rapid detection of infectious bronchitis virus in infected chicken tissues.
Bronchitis
Sequence of the S gene from a virulent British field isolate of transmissible gastroenteritis virus.
Bunyaviridae Infections
Suppression of the IFN-? and -? Induction through Sequestering IRF7 into Viral Inclusion Bodies by Nonstructural Protein NSs in Severe Fever with Thrombocytopenia Syndrome Bunyavirus Infection.
Burkitt Lymphoma
Preparative high-resolution two-dimensional electrophoresis enables the identification of RNA polymerase B transcription factor 3 as an apoptosis-associated protein in the human BL60-2 Burkitt lymphoma cell line.
Calcinosis
Distinctive cutaneous and systemic features associated with specific antimyositis antibodies in adults with dermatomyositis: a prospective multicentric study of 117 patients.
Caliciviridae Infections
Incidence of and factors associated with false positives in laboratory diagnosis of norovirus infection by amplification of the RNA-dependent RNA polymerase gene.
Candidiasis
Post-translational modification directs nuclear and hyphal tip localization of Candida albicans mRNA-binding protein Slr1.
Carcinogenesis
A mirror of two faces: Lin28 as a master regulator of both miRNA and mRNA.
Carcinogenesis
Abnormal expression of TFIIIB subunits and RNA Pol III genes is associated with hepatocellular carcinoma.
Carcinogenesis
Alpha CP-4, encoded by a putative tumor suppressor gene at 3p21, but not its alternative splice variant alpha CP-4a, is underexpressed in lung cancer.
Carcinogenesis
An RNA-binding Protein, Lin28, Recognizes and Remodels G-quartets in the MicroRNAs (miRNAs) and mRNAs It Regulates.
Carcinogenesis
Anticarcinogenic effects of retinoids in animals.
Carcinogenesis
Applying a high-throughput fluorescence polarization assay for the discovery of chemical probes blocking La:RNA interactions in vitro and in cells.
Carcinogenesis
Carcinoid tumour associated with enterovirus infection.
Carcinogenesis
CDX2 regulation by the RNA-binding protein MEX3A: impact on intestinal differentiation and stemness.
Carcinogenesis
Clinical Significance of Methylation and Reduced Expression of the Quaking Gene in Colorectal Cancer.
Carcinogenesis
Differential Regulation of
Carcinogenesis
Differential regulation of autophagy by STAU1 in alveolar rhabdomyosarcoma and non-transformed skeletal muscle cells.
Carcinogenesis
Distinct roles for the RNA-binding protein Staufen1 in prostate cancer.
Carcinogenesis
Does Lin28 Antagonize miRNA-Mediated Repression by Displacing miRISC from Target mRNAs?
Carcinogenesis
Dysregulated transcription across diverse cancer types reveals the importance of RNA-binding protein in carcinogenesis.
Carcinogenesis
Epstein-Barr virus induces cellular transcription factors to allow active expression of EBER genes by RNA polymerase III.
Carcinogenesis
Expression of exogenous LIN28 contributes to proliferation and survival of mouse primary cortical neurons in vitro.
Carcinogenesis
Finding, Conducting, and Nurturing Science: A Virologist's Memoir.
Carcinogenesis
FUS-mediated regulation of alternative RNA processing in neurons: insights from global transcriptome analysis.
Carcinogenesis
Fusion of the RBP56 and CHN genes in extraskeletal myxoid chondrosarcomas with translocation t(9;17)(q22;q11).
Carcinogenesis
Genetic variants of the LIN28B gene predict severe radiation pneumonitis in patients with non-small cell lung cancer treated with definitive radiation therapy.
Carcinogenesis
Genome-wide analysis of Musashi-2 targets reveals novel functions in governing epithelial cell migration.
Carcinogenesis
Genomic analyses of musashi1 downstream targets show a strong association with cancer-related processes.
Carcinogenesis
Hepatitis B virus X protein enhances androgen receptor-responsive gene expression depending on androgen level.
Carcinogenesis
Hepatitis C virus nonstructural protein NS(3) and telomerase activity.
Carcinogenesis
Heterogeneous Nuclear Ribonucleoprotein A2/B1 Regulates the Selfrenewal and Pluripotency of Human Embryonic Stem Cells via the Control of the G1/S Transition.
Carcinogenesis
hnRNP A1 antagonizes cellular senescence and senescence-associated secretory phenotype via regulation of SIRT1 mRNA stability.
Carcinogenesis
HnRNP-L promotes prostate cancer progression by enhancing cell cycling and inhibiting apoptosis.
Carcinogenesis
Human T-cell leukemia virus type 1 Tax and cellular transformation.
Carcinogenesis
HuR cytoplasmic expression is associated with increased cyclin A expression and inferior disease-free survival in patients with gastrointestinal stromal tumours (GISTs).
Carcinogenesis
HuR cytoplasmic expression is associated with increased cyclin A expression and poor outcome with upper urinary tract urothelial carcinoma.
Carcinogenesis
Identification of RNA-binding proteins that partner with Lin28a to regulate Dnmt3a expression.
Carcinogenesis
IGF2BP3 facilitates cell proliferation and tumorigenesis via modulation of JAK/STAT signalling pathway in human bladder cancer.
Carcinogenesis
Immunohistochemical Analysis Revealed a Correlation between Musashi-2 and Cyclin-D1 Expression in Patients with Oral Squamous Cells Carcinoma.
Carcinogenesis
Impact of HuR inhibition by the small molecule MS-444 on colorectal cancer cell tumorigenesis.
Carcinogenesis
Inhibition of chemical carcinogenesis: increased activity of soluble RNA polymerase in the liver of rats protected against 3'MeDAB hepatocarcinogenesis by dietary chloramphenicol.
Carcinogenesis
Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) is an important protumorigenic factor in hepatocellular carcinoma.
Carcinogenesis
Interfering with HuR-RNA Interaction: Design, Synthesis and Biological Characterization of Tanshinone Mimics as Novel, Effective HuR Inhibitors.
Carcinogenesis
Intestinal epithelial HuR modulates distinct pathways of proliferation and apoptosis and attenuates small intestinal and colonic tumor development.
Carcinogenesis
KH-type splicing regulatory protein (KHSRP) contributes to tumorigenesis by promoting miR-26a maturation in small cell lung cancer.
Carcinogenesis
LIN28 Binds Messenger RNAs at GGAGA Motifs and Regulates Splicing Factor Abundance.
Carcinogenesis
LIN28 cooperates with WNT signaling to drive invasive intestinal and colorectal adenocarcinoma in mice and humans.
Carcinogenesis
LIN28 Expression in Rat Spinal Cord After Injury.
Carcinogenesis
Msi1 promotes tumor progression by epithelial-to-mesenchymal transition in cervical cancer.
Carcinogenesis
Musashi-1, an RNA-binding protein, is indispensable for survival of photoreceptors.
Carcinogenesis
Myeloid cell expression of the RNA-binding protein HuR protects mice from pathologic inflammation and colorectal carcinogenesis.
Carcinogenesis
Nucleolin Promotes IRES-Driven Translation of Foot-and-Mouth Disease Virus by Supporting the Assembly of Translation Initiation Complexes.
Carcinogenesis
Original Article/Liver hMex-3A is associated with poor prognosis and contributes to the progression of hepatocellular carcinoma.
Carcinogenesis
Overexpression of Lin28b in Neural Stem Cells is Insufficient for Brain Tumor Formation, but Induces Pathological Lobulation of the Developing Cerebellum.
Carcinogenesis
Overexpression of Musashi-1 protein is associated with progression and poor prognosis of gastric cancer.
Carcinogenesis
Prognostic Value of the Expression of DNA Repair-Related Biomarkers Mediated by Alcohol in Gastric Cancer Patients.
Carcinogenesis
Proteomics-Based Evidence for a Pro-Oncogenic Role of ESRP1 in Human Colorectal Cancer Cells.
Carcinogenesis
RALY may cause an aggressive biological behavior and a dismal prognosis in non-small-cell lung cancer.
Carcinogenesis
Reversible acetylation of Lin28 mediated by PCAF and SIRT1.
Carcinogenesis
RNA-binding protein MSI2 isoforms expression and regulation in progression of triple-negative breast cancer.
Carcinogenesis
RNase L downmodulation of the RNA-binding protein, HuR, and cellular growth.
Carcinogenesis
Role of RNA-binding protein 5 in the diagnosis and chemotherapeutic response of lung cancer.
Carcinogenesis
Role of the RNA-binding protein HuR in colon carcinogenesis.
Carcinogenesis
Selective inhibition of RNA polymerase activity in rat liver nuclei by 4-(dimethylamino) azobenzene, and effect of nitrofurans on liver RNA metabolism associated with prevention of carcinogenesis.
Carcinogenesis
Serine-phosphorylated STAT3 promotes tumorigenesis via modulation of RNA polymerase transcriptional activity.
Carcinogenesis
Structure of Musashi1 in a complex with target RNA: the role of aromatic stacking interactions.
Carcinogenesis
The Aberrant Expression of MicroRNA-125a-5p/IGF2BP3 Axis in Advanced Gastric Cancer and Its Clinical Relevance.
Carcinogenesis
The Grainyhead transcription factor Grhl3/Get1 suppresses miR-21 expression and tumorigenesis in skin: modulation of the miR-21 target MSH2 by RNA-binding protein DND1.
Carcinogenesis
The human homologue of the RNA polymerase II-associated factor 1 (hPaf1), localized on the 19q13 amplicon, is associated with tumorigenesis.
Carcinogenesis
The HuR CMLD-2 inhibitor exhibits antitumor effects via MAD2 downregulation in thyroid cancer cells.
Carcinogenesis
The JNKs differentially regulate RNA polymerase III transcription by coordinately modulating the expression of all TFIIIB subunits.
Carcinogenesis
The oncogenic RNA-binding protein Musashi1 is regulated by HuR via mRNA translation and stability in glioblastoma cells.
Carcinogenesis
The oncogenic RNA-binding protein Musashi1 is regulated by tumor suppressor miRNAs.
Carcinogenesis
The pluripotency factor LIN28B is involved in oral carcinogenesis and associates with tumor aggressiveness and unfavorable prognosis.
Carcinogenesis
The RNA-binding protein LARP1 is a post-transcriptional regulator of survival and tumorigenesis in ovarian cancer.
Carcinogenesis
The RNA-binding protein QKI suppresses tumorigenesis of clear cell renal cell carcinoma by regulating the expression of HIF-1?.
Carcinogenesis
The RNA-binding protein Sam68 regulates tumor cell viability and hepatic carcinogenesis by inhibiting the transcriptional activity of FOXOs.
Carcinogenesis
The RNA-binding protein SORBS2 suppresses hepatocellular carcinoma tumourigenesis and metastasis by stabilizing RORA mRNA.
Carcinogenesis
The role of RNA-binding protein tristetraprolin in cancer and immunity.
Carcinogenesis
The Role of the RNA-Binding Protein Family MEX-3 in Tumorigenesis.
Carcinogenesis
The role of the RNA-binding protein Sam68 in mammary tumourigenesis.
Carcinogenesis
Transcriptional mutagenesis and its potential roles in the etiology of cancer and bacterial antibiotic resistance.
Carcinogenesis
Ubiquitin-Proteasome System Regulation of an Evolutionarily Conserved RNA Polymerase II-Associated Factor 1 Involved in Pancreatic Oncogenesis.
Carcinoid Tumor
Carcinoid tumour associated with enterovirus infection.
Carcinoma
A TARBP2 mutation in human cancer impairs microRNA processing and DICER1 function.
Carcinoma
Analysis of RNA-binding protein IMP3 to predict metastasis and prognosis of renal-cell carcinoma: a retrospective study.
Carcinoma
Analysis of Tertiary Interactions between SART3 and U6 Small Nuclear RNA Using Modified Nanocapillaries.
Carcinoma
Attenuation of the ELAV1-like protein HuR sensitizes adenocarcinoma cells to the intrinsic apoptotic pathway by increasing the translation of caspase-2L.
Carcinoma
Autoantibodies against the Hel-N1 RNA-binding protein among patients with lung carcinoma: an association with type I anti-neuronal nuclear antibodies.
Carcinoma
Binding of a SART3 tumor-rejection antigen to a pre-mRNA splicing factor RNPS1: a possible regulation of splicing by a complex formation.
Carcinoma
Characterization of self-assembled virus-like particles of merkel cell polyomavirus.
Carcinoma
Characterization of squamous cell carcinoma in an organotypic culture via subsurface non-linear optical molecular imaging.
Carcinoma
Cytoplasmic steroid effects on nuclear RNA polymerase activity in canine mammary carcinomas.
Carcinoma
De Novo RNA Synthesis by RNA-Dependent RNA Polymerase Activity of Telomerase Reverse Transcriptase.
Carcinoma
Detection of hepatitis C virus NS5 protein and genome in Chinese carcinoma of the extrahepatic bile duct and its significance.
Carcinoma
Different Wnt-5A gene expressions in the renal cell carcinoma GRC-1 cell line during the cell cycle.
Carcinoma
Expression of cold-inducible RNA-binding protein (CIRP) in renal cell carcinoma and the effect of CIRP downregulation cell proliferation and chemosensitivity to gemcitabine.
Carcinoma
Expression of Cold-Inducible RNA-Binding Protein in Normal Skin, Actinic Keratosis and Squamous Cell Carcinoma.
Carcinoma
Expression of RNA-binding protein LIN28 in classic gastric hepatoid carcinomas, gastric fetal type gastrointestinal adenocarcinomas, and hepatocellular carcinomas: An immunohistochemical study with comparison to SALL4, alpha-fetoprotein, glypican-3, and Hep Par1.
Carcinoma
Expression of the oncofetal protein IGF2BP3 in endometrial clear cell carcinoma: assessment of frequency and significance.
Carcinoma
Expression of the RNA-binding protein IMP1 correlates with poor prognosis in ovarian carcinoma.
Carcinoma
Genomic Fabric Remodeling in Metastatic Clear Cell Renal Cell Carcinoma (ccRCC): A New Paradigm and Proposal for a Personalized Gene Therapy Approach.
Carcinoma
Genotoxic stress causes the accumulation of the splicing regulator Sam68 in nuclear foci of transcriptionally active chromatin.
Carcinoma
Human papillomavirus type 33 in a tonsillar carcinoma generates its putative E7 mRNA via two E6* transcript species which are terminated at different early region poly(A) sites.
Carcinoma
Implication of RNA-binding protein La in proliferation, migration and invasion of lymph node-metastasized hypopharyngeal SCC cells.
Carcinoma
In-vitro inhibition of spring viremia of carp virus replication by RNA interference targeting the RNA-dependent RNA polymerase gene.
Carcinoma
Inhibition of nuclear DNA-dependent RNA polymerases from mouse ascites tumors and liver by glycerol.
Carcinoma
Inhibition of RNA-Binding Protein Musashi-1 Suppresses Malignant Properties and Reverses Paclitaxel Resistance in Ovarian Carcinoma.
Carcinoma
Insulin-like Growth Factor Messenger RNA-binding Protein 3 Expression Helps Prognostication in Patients with Upper Tract Urothelial Carcinoma.
Carcinoma
Integrated Analysis of the Prognosis-Associated RNA-Binding Protein Genes and Candidate Drugs in Renal Papillary Cell Carcinoma.
Carcinoma
KOC (K homology domain containing protein overexpressed in cancer): a novel molecular marker that distinguishes between benign and malignant lesions of the pancreas.
Carcinoma
LncRNA OIP5-AS1/cyrano sponges RNA-binding protein HuR.
Carcinoma
MicroRNA-24 targeting RNA-binding protein DND1 in tongue squamous cell carcinoma.
Carcinoma
Muscle-Specific FXR1 Isoforms in Squamous Cell Cancer.
Carcinoma
Parameters of RNA-dependent RNA polymerase activity in a mengovirus-infected Ehrlich ascites carcinoma cell-free system.
Carcinoma
Prognostic value of antibodies to Merkel cell polyomavirus T-Antigens and VP1 protein in Merkel cell carcinoma patients.
Carcinoma
Regulation of neuronal survival and morphology by the E3 ubiquitin ligase RNF157.
Carcinoma
Repression of caspase-3 and RNA-binding protein HuR cleavage by cyclooxygenase-2 promotes drug resistance in oral squamous cell carcinoma.
Carcinoma
RNA-binding protein CELF1 promotes tumor growth and alters gene expression in oral squamous cell carcinoma.
Carcinoma
RNA-Binding Protein IGF2BP1 in Cutaneous Squamous Cell Carcinoma.
Carcinoma
RNA-binding protein QKI-5 inhibits the proliferation of clear cell renal cell carcinoma via post-transcriptional stabilization of RASA1 mRNA.
Carcinoma
RNA-binding protein SORBS2 suppresses clear cell renal cell carcinoma metastasis by enhancing MTUS1 mRNA stability.
Carcinoma
Role of the RNA-binding protein HuR in colon carcinogenesis.
Carcinoma
Role of the RNA-binding protein HuR in human renal cell carcinoma.
Carcinoma
The expression of RNA-binding protein RBM38 decreased in renal cell carcinoma and represses renal cancer cell proliferation, migration, and invasion.
Carcinoma
The La protein counteracts cisplatin-induced cell death by stimulating protein synthesis of anti-apoptotic factor Bcl2.
Carcinoma
The RNA-binding protein PCBP2 facilitates gastric carcinoma growth by targeting miR-34a.
Carcinoma
The RNA-binding protein QKI suppresses tumorigenesis of clear cell renal cell carcinoma by regulating the expression of HIF-1?.
Carcinoma
The RNA-binding protein RBM47 inhibits non-small cell lung carcinoma metastasis through modulation of AXIN1 mRNA stability and Wnt/?-catentin signaling.
Carcinoma
The RNA-binding protein Sam68 contributes to proliferation and survival of human prostate cancer cells.
Carcinoma
Tumor-promoting function and prognostic significance of the RNA-binding protein T-cell intracellular antigen-1 in esophageal squamous cell carcinoma.
Carcinoma
Up-regulated expression of the MAT-8 gene in prostate cancer and its siRNA-mediated inhibition of expression induces a decrease in proliferation of human prostate carcinoma cells.
Carcinoma
Use of IMP3 in identification of carcinoma in fine needle aspiration biopsies of pancreas.
Carcinoma
von Hippel-Lindau tumor suppressor gene-dependent mRNA stabilization of the survival factor parathyroid hormone-related protein in human renal cell carcinoma by the RNA-binding protein HuR.
Carcinoma
Zinc finger RNA-binding protein promotes non-small-cell carcinoma growth and tumor metastasis by targeting the Notch signaling pathway.
Carcinoma
Zmat3 Is a Key Splicing Regulator in the p53 Tumor Suppression Program.
Carcinoma
[RNA polymerase activity of Ehrlich ascites carcinoma nuclei in relation to the mechanism of action of N-alkyl-N-nitrosourea]
Carcinoma, Ductal
Immunohistochemical evaluation of reverse transcriptase in breast carcinoma with polyclonal antibodies raised in rabbit.
Carcinoma, Ehrlich Tumor
DNA dependent RNA polymerase from Ehrlich ascites tumor cells. II. Factors stimulating the activity of RNA polymerase II.
Carcinoma, Ehrlich Tumor
DNA dependent RNA polymerase from ehrlich ascites tumor cells. IV. A novel protein repressing RNA polymerase II.
Carcinoma, Ehrlich Tumor
DNA dependent RNA polymerase from Ehrlich ascites tumor cells. V. Characterization of a factor repressing RNA polymerase II as a ribonucleoprotein.
Carcinoma, Ehrlich Tumor
DNA-dependent RNA polymerase from Ehrlich ascites tumor cells. I. Partial purification and characterization of RNA polymerase II.
Carcinoma, Ehrlich Tumor
Effect of cis-diamminedichloroplatinum(II) and other platinum compounds on the RNA polymerase reaction.
Carcinoma, Ehrlich Tumor
Inhibition of ribonucleases by ribonucleotides and transition state analogs in cell-free extracts from Ehrlich ascites tumor cells.
Carcinoma, Ehrlich Tumor
Mouse DNA polymerase accompanied by a novel RNA polymerase activity: purification and partial characterization.
Carcinoma, Ehrlich Tumor
Partial purification and characterization of RNA polymerase from nuclei of Ehrlich ascites tumor cells.
Carcinoma, Ehrlich Tumor
Study of the loosely bound non-histone chromatin proteins. Stimulation of deoxyribonucleic acid-templated ribonucleic acid synthesis by a specific deoxyribonucleic acid-binding phosphoprotein fraction.
Carcinoma, Embryonal
c-jun inhibited the alternative splicing of neuron-specific amyloid precursor protein, but stimulated the non-neuron type one in P19 EC cells.
Carcinoma, Hepatocellular
A comparative study of "soluble" RNA polymerase activity of Zajdela hepatoma ascites cells and calf thymus.
Carcinoma, Hepatocellular
A family of IGF-II mRNA binding proteins (IMP) involved in RNA trafficking.
Carcinoma, Hepatocellular
Aberrant expression of fetal RNA-binding protein p62 in liver cancer and liver cirrhosis.
Carcinoma, Hepatocellular
Circ-MALAT1 Functions as Both an mRNA Translation Brake and a microRNA Sponge to Promote Self-Renewal of Hepatocellular Cancer Stem Cells.
Carcinoma, Hepatocellular
Cloning and characterization of a novel 90 kDa 'companion' auto-antigen of p62 overexpressed in cancer.
Carcinoma, Hepatocellular
Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virus.
Carcinoma, Hepatocellular
Cyclin L2, a novel RNA polymerase II-associated cyclin, is involved in pre-mRNA splicing and induces apoptosis of human hepatocellular carcinoma cells.
Carcinoma, Hepatocellular
Cyclooxygenase-2 is a target of microRNA-16 in human hepatoma cells.
Carcinoma, Hepatocellular
Expression of Concern: Cyclin L2, a novel RNA polymerase II-associated cyclin, is involved in pre-mRNA splicing and induces apoptosis of human hepatocellular carcinoma cells.
Carcinoma, Hepatocellular
Expression of RNA-binding protein LIN28 in classic gastric hepatoid carcinomas, gastric fetal type gastrointestinal adenocarcinomas, and hepatocellular carcinomas: An immunohistochemical study with comparison to SALL4, alpha-fetoprotein, glypican-3, and Hep Par1.
Carcinoma, Hepatocellular
Expression of the Musashi1 gene encoding the RNA-binding protein in human hepatoma cell lines.
Carcinoma, Hepatocellular
HCV NS5A activates the mammalian target of rapamycin (mTOR) pathway contributing to cell survival via disrupting the interaction between FK506-binding protein 38 (FKBP38) and mTOR.
Carcinoma, Hepatocellular
Hepatitis B virus X protein promotes interleukin-7 receptor expression via NF-?B and Notch1 pathway to facilitate proliferation and migration of hepatitis B virus-related hepatoma cells.
Carcinoma, Hepatocellular
Hepatitis C virus NS5A promotes insulin resistance through IRS-1 serine phosphorylation and increased gluconeogenesis.
Carcinoma, Hepatocellular
Hepatitis C virus replication is modulated by the interaction of non-structural protein NS5B and fatty acid synthase.
Carcinoma, Hepatocellular
High expression of neuro-oncological ventral antigen 1 correlates with poor prognosis in hepatocellular carcinoma.
Carcinoma, Hepatocellular
Hormonal effect on nucleolar RNA polymerase in normal liver and hepatoma cells.
Carcinoma, Hepatocellular
Identification and characterization of a novel protein that regulates RNA-protein interaction.
Carcinoma, Hepatocellular
Identification of a Novel TAR RNA-Binding Protein 2 Modulator with Potential Therapeutic Activity against Hepatocellular Carcinoma.
Carcinoma, Hepatocellular
Immunolocalization of a subnucleolar nucleoprotein complex containing RNA polymerase 1 in ascites hepatoma cells using monoclonal antibodies.
Carcinoma, Hepatocellular
Multi-enzyme-targeted chemotherapy by acivicin and actinomycin.
Carcinoma, Hepatocellular
Protective effect of the RNA-binding protein RBM10 in hepatocellular carcinoma.
Carcinoma, Hepatocellular
RBMY, a male germ cell-specific RNA-binding protein, activated in human liver cancers and transforms rodent fibroblasts.
Carcinoma, Hepatocellular
Real-world safety and efficacy of sofosbuvir and ledipasvir for elderly patients.
Carcinoma, Hepatocellular
Reversible inhibition of induction of mengovirus RNA polymerase and of virus maturation in Novikoff rat hepatoma cells by phenethyl alcohol.
Carcinoma, Hepatocellular
RNA-binding protein AUF1 suppresses miR-122 biogenesis by down-regulating Dicer1 in hepatocellular carcinoma.
Carcinoma, Hepatocellular
RNA-binding protein Dnd1 inhibits epithelial-mesenchymal transition and cancer stem cell-related traits on hepatocellular carcinoma cells.
Carcinoma, Hepatocellular
RNA-binding protein insulin-like growth factor II mRNA-binding protein 3 expression promotes tumor invasion and predicts early recurrence and poor prognosis in hepatocellular carcinoma.
Carcinoma, Hepatocellular
RNA-binding protein RBM6 acts as a tumor suppressor gene to inhibit the progression of hepatocellular carcinoma.
Carcinoma, Hepatocellular
RNA-binding protein ZFP36/TTP protects against ferroptosis by regulating autophagy signaling pathway in hepatic stellate cells.
Carcinoma, Hepatocellular
Role of La autoantigen and polypyrimidine tract-binding protein in HCV replication.
Carcinoma, Hepatocellular
Suppression of miR-199a maturation by HuR is crucial for hypoxia-induced glycolytic switch in hepatocellular carcinoma.
Carcinoma, Hepatocellular
The hepatitis C viral nonstructural protein 5A stabilizes growth-regulatory human transcripts.
Carcinoma, Hepatocellular
The RNA-binding protein RBM3 promotes cell proliferation in hepatocellular carcinoma by regulating circular RNA SCD-circRNA 2 production.
Carcinoma, Hepatocellular
The RNA-binding protein SORBS2 suppresses hepatocellular carcinoma tumourigenesis and metastasis by stabilizing RORA mRNA.
Carcinoma, Hepatocellular
Transcriptionally active RNA polymerases from Morris hepatomas and rat liver. Elucidation of the mechanism for the preferential increase in the tumour RNA polymerase I.
Carcinoma, Hepatocellular
Utilization of RNA polymerase I promoter and terminator sequences to develop a DNA transfection system for the study of hepatitis C virus internal ribosomal entry site-dependent translation.
Carcinoma, Hepatocellular
Withdrawal: Cyclin L2, a novel RNA polymerase II-associated cyclin, is involved in pre-mRNA splicing and induces apoptosis of human hepatocellular carcinoma cells.
Carcinoma, Hepatocellular
[Effect of 10-hydroxycamptothecin on nuclear RNA polymerase activity in hepatoma cells in mice]
Carcinoma, Hepatocellular
[Inhibition of parvovirus H-1 on transplantable human hepatoma and its histological and histobiochemical studies]
Carcinoma, Hepatocellular
[Significance of a novel fetal RNA-binding protein p62 expression in hepatocellular carcinoma]
Carcinoma, Lobular
Immunohistochemical evaluation of reverse transcriptase in breast carcinoma with polyclonal antibodies raised in rabbit.
Carcinoma, Merkel Cell
Characterization of self-assembled virus-like particles of merkel cell polyomavirus.
Carcinoma, Merkel Cell
Prognostic value of antibodies to Merkel cell polyomavirus T-Antigens and VP1 protein in Merkel cell carcinoma patients.
Carcinoma, Neuroendocrine
Extrapulmonary small cell carcinomas express K homology domain containing protein overexpressed in cancer, but carcinoid tumors do not.
Carcinoma, Neuroendocrine
High-grade neuroendocrine carcinomas of the lung express K homology domain containing protein overexpressed in cancer but carcinoid tumors do not.
Carcinoma, Non-Small-Cell Lung
Expression profile, clinical significance, and biological function of insulin-like growth factor 2 messenger RNA-binding proteins in non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
MUC1-C Induces the LIN28B?LET-7?HMGA2 Axis to Regulate Self-Renewal in NSCLC.
Carcinoma, Non-Small-Cell Lung
Musashi-2 (MSI2) regulates epidermal growth factor receptor (EGFR) expression and response to EGFR inhibitors in EGFR-mutated non-small cell lung cancer (NSCLC).
Carcinoma, Non-Small-Cell Lung
RNA-binding protein KHSRP promotes tumor growth and metastasis in non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
The Expression of RNA-Binding Protein HuR in Non-Small Cell Lung Cancer Correlates with Vascular Endothelial Growth Factor-C Expression and Lymph Node Metastasis.
Carcinoma, Non-Small-Cell Lung
The oncogenic RNA-binding protein SRSF1 regulates LIG1 in non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
The RNA-binding protein HuR stabilizes the cytosolic phospholipase A2{alpha} mRNA under interleukin-1{beta} treatment in non-small cell lung cancer A549 cells.
Carcinoma, Non-Small-Cell Lung
The RNA-binding protein RBM47 inhibits non-small cell lung carcinoma metastasis through modulation of AXIN1 mRNA stability and Wnt/?-catentin signaling.
Carcinoma, Non-Small-Cell Lung
The RNA-binding protein Sam68 is critical for non-small cell lung cancer cell proliferation by regulating Wnt/?-catenin pathway.
Carcinoma, Ovarian Epithelial
Expression of the RNA-binding protein RBM3 is associated with a favourable prognosis and cisplatin sensitivity in epithelial ovarian cancer.
Carcinoma, Renal Cell
Different Wnt-5A gene expressions in the renal cell carcinoma GRC-1 cell line during the cell cycle.
Carcinoma, Renal Cell
Expression of cold-inducible RNA-binding protein (CIRP) in renal cell carcinoma and the effect of CIRP downregulation cell proliferation and chemosensitivity to gemcitabine.
Carcinoma, Renal Cell
Genomic Fabric Remodeling in Metastatic Clear Cell Renal Cell Carcinoma (ccRCC): A New Paradigm and Proposal for a Personalized Gene Therapy Approach.
Carcinoma, Renal Cell
Influence of the RNA-binding protein HuR in pVHL-regulated p53 expression in renal carcinoma cells.
Carcinoma, Renal Cell
RNA-binding protein QKI-5 inhibits the proliferation of clear cell renal cell carcinoma via post-transcriptional stabilization of RASA1 mRNA.
Carcinoma, Renal Cell
RNA-binding protein SORBS2 suppresses clear cell renal cell carcinoma metastasis by enhancing MTUS1 mRNA stability.
Carcinoma, Renal Cell
Role of the RNA-binding protein HuR in human renal cell carcinoma.
Carcinoma, Renal Cell
The expression of RNA-binding protein RBM38 decreased in renal cell carcinoma and represses renal cancer cell proliferation, migration, and invasion.
Carcinoma, Renal Cell
The RNA-binding protein QKI suppresses tumorigenesis of clear cell renal cell carcinoma by regulating the expression of HIF-1?.
Carcinoma, Renal Cell
von Hippel-Lindau tumor suppressor gene-dependent mRNA stabilization of the survival factor parathyroid hormone-related protein in human renal cell carcinoma by the RNA-binding protein HuR.
Carcinoma, Squamous Cell
Characterization of squamous cell carcinoma in an organotypic culture via subsurface non-linear optical molecular imaging.
Carcinoma, Squamous Cell
Expression of Cold-Inducible RNA-Binding Protein in Normal Skin, Actinic Keratosis and Squamous Cell Carcinoma.
Carcinoma, Squamous Cell
MicroRNA-24 targeting RNA-binding protein DND1 in tongue squamous cell carcinoma.
Carcinoma, Squamous Cell
Muscle-Specific FXR1 Isoforms in Squamous Cell Cancer.
Carcinoma, Squamous Cell
RNA-Binding Protein IGF2BP1 in Cutaneous Squamous Cell Carcinoma.
Carcinoma, Squamous Cell
The La protein counteracts cisplatin-induced cell death by stimulating protein synthesis of anti-apoptotic factor Bcl2.
Cardiac Conduction System Disease
Aberrant Expression of a Non-muscle RBFOX2 Isoform Triggers Cardiac Conduction Defects in Myotonic Dystrophy.
Cardiomegaly
A novel serum protein of molecular weight 182 kDa: a molecular marker for an early detection of increased left ventricular mass in patients with cardiac hypertrophy.
Cardiomegaly
Biochemical correlates of cardiac hypertrophy. I. Experimental model; changes in heart weight, RNA content, and nuclear RNA polymerase activity.
Cardiomegaly
Cardiac isoform of alpha-2 macroglobin, a novel serum protein, may induce cardiac hypertrophy in rats.
Cardiomegaly
Catecholamine induced cardiac hypertrophy.
Cardiomegaly
Direct injection and expression in vivo of full-length cDNA of the cardiac isoform of alpha-2 macroglobulin induces cardiac hypertrophy in the rat heart.
Cardiomegaly
Enhanced myocardial RNA synthesis in spontaneously hypertensive rats possible role of high-mobility group non-histone proteins.
Cardiomegaly
Programmed Cell Death 5 Provides Negative Feedback on Cardiac Hypertrophy Through the Stabilization of Sarco/Endoplasmic Reticulum Ca2+-ATPase 2a Protein.
Cardiomegaly
RNA polymerase and adenyl cyclase in cardiac hypertrophy and cardiomyopathy.
Cardiomyopathies
RNA polymerase and adenyl cyclase in cardiac hypertrophy and cardiomyopathy.
Cardiomyopathies
RNA-binding protein RBM24 is required for sarcomere assembly and heart contractility.
Cardiomyopathy, Dilated
Increased Cardiac Arrhythmogenesis Associated With Gap Junction Remodeling With Upregulation of RNA-Binding Protein FXR1.
Cardiomyopathy, Dilated
Rbm20-deficient cardiogenesis reveals early disruption of RNA processing and sarcomere remodeling establishing a developmental etiology for dilated cardiomyopathy.
Cardiomyopathy, Dilated
RNA-binding protein RBM20 represses splicing to orchestrate cardiac pre-mRNA processing.
Cardiovascular Diseases
Circular RNAs are a novel type of non-coding RNAs in ROS regulation, cardiovascular metabolic inflammations and cancers.
Cardiovascular Diseases
Switch to dolutegravir and unboosted atazanavir in HIV-1 infected patients with undetectable viral load and long exposure to antiretroviral therapy.
Cardiovascular Diseases
The Role of PB1 Domain Proteins in Endothelial Cell Dysfunction and Disease.
Cervical Intraepithelial Neoplasia
Enzyme-linked immunosorbent assay for p16(INK4a) - a new triage test for the detection of cervical intraepithelial neoplasia?
Chagas Disease
TcUBP-1, a developmentally regulated U-rich RNA-binding protein involved in selective mRNA destabilization in trypanosomes.
Chickenpox
RNA polymerase III and antiviral innate immune response.
Cholangiocarcinoma
MSI2 knockdown represses extrahepatic cholangiocarcinoma growth and invasion by inhibiting epithelial-mesenchymal transition.
Cholangitis, Sclerosing
Identification of beta-subunit of bacterial RNA-polymerase--a non-species-specific bacterial protein--as target of antibodies in primary biliary cirrhosis.
Cholera
Colloidal gold: a pluripotent receptor probe.
Cholera
Foot-and-mouth disease virus VP1 protein fused with cholera toxin B subunit expressed in Chlamydomonas reinhardtii chloroplast.
Cholera
In-silico prediction of dual function of DksA like hypothetical protein in V. cholerae O395 genome.
Cholera
Multiplex polymerase chain reaction-based assay for the specific detection of toxin-producing Vibrio cholerae in fish and fishery products.
Cholera
Post-transcriptional regulation of cholera toxin production in Vibrio cholerae by the stringent response regulator DksA.
Cholera
Tracking the Elusive Function of Bacillus subtilis Hfq.
Chondrosarcoma
A renal cell carcinoma with EWSR1-TFE3 fusion gene.
Chondrosarcoma
Diagnostic Utility of Molecular Investigation in Extraskeletal Myxoid Chondrosarcoma.
Choriocarcinoma
Regulation of Mcl-1 by SRSF1 and SRSF5 in cancer cells.
Chronic Periodontitis
Differential expression of microRNAs let-7a, miR-125b, miR-100, and miR-21 and interaction with NF-kB pathway genes in periodontitis pathogenesis.
Chronic Periodontitis
Periodontal pathogens in subgingival plaque of HIV-positive subjects with chronic periodontitis.
Ciliopathies
Role of the RNA-binding protein Bicaudal-C1 and interacting factors in cystic kidney diseases.
Classical Swine Fever
A unique intra-molecular fidelity-modulating mechanism identified in a viral RNA-dependent RNA polymerase.
Classical Swine Fever
An induced-fit de novo initiation mechanism suggested by a pestivirus RNA-dependent RNA polymerase.
Classical Swine Fever
Autophagy Induced by the N-Terminus of the Classic Swine Fever Virus Nonstructural Protein 5A Protein Promotes Viral Replication.
Classical Swine Fever
Baculovirus surface display of NS3 nonstructural protein of classical swine fever virus.
Classical Swine Fever
Cellular Hsp27 interacts with classical swine fever virus NS5A protein and negatively regulates viral replication by the NF-?B signaling pathway.
Classical Swine Fever
Characterisation of interaction between NS3 and NS5B protein of classical swine fever virus by deletion of terminal sequences of NS5B.
Classical Swine Fever
Characterization of classical swine fever virus (CSFV) nonstructural protein 3 (NS3) helicase activity and its modulation by CSFV RNA-dependent RNA polymerase.
Classical Swine Fever
Characterization of RNA-dependent RNA polymerase activity of CSFV NS5B proteins expressed in Escherichia coli.
Classical Swine Fever
Characterization of the N-terminal domain of classical swine fever virus RNA-dependent RNA polymerase.
Classical Swine Fever
Classical swine fever virus nonstructural protein p7 modulates infectious virus production.
Classical Swine Fever
Classical swine fever virus NS3 enhances RNA-dependent RNA polymerase activity by binding to NS5B.
Classical Swine Fever
Classical swine fever virus NS5B protein suppresses the inhibitive effect of NS5A on viral translation by binding to NS5A.
Classical Swine Fever
Classical swine fever virus NS5B-GFP fusion protein possesses an RNA-dependent RNA polymerase activity.
Classical Swine Fever
Classical Swine Fever Virus p7 Protein Interacts with Host Protein CAMLG and Regulates Calcium Permeability at the Endoplasmic Reticulum.
Classical Swine Fever
Classical swine fever virus p7 protein is a viroporin involved in virulence in swine.
Classical Swine Fever
Crystal Structure of Classical Swine Fever Virus NS5B Reveals a Novel N-Terminal Domain.
Classical Swine Fever
De novo RNA synthesis and homology modeling of the classical swine fever virus RNA polymerase.
Classical Swine Fever
De novo RNA synthesis by a recombinant classical swine fever virus RNA-dependent RNA polymerase.
Classical Swine Fever
Diagnostic evaluation of a real-time reverse transcriptase PCR assay for detection of classical swine fever virus.
Classical Swine Fever
Episodic adaptive diversification of classical swine fever virus RNA-dependent RNA polymerase NS5B.
Classical Swine Fever
Functional properties of a monoclonal antibody inhibiting the hepatitis C virus RNA-dependent RNA polymerase.
Classical Swine Fever
Inhibition of expression of rna polymerase with small interfering RNAs targeting a conserved motif in the respective viral genes in viruses of the family Flaviviridae.
Classical Swine Fever
Intra-host variation structure of classical swine fever virus NS5B in relation to antiviral therapy.
Classical Swine Fever
Molecular cloning and nucleotide sequence of the genome of hog cholera virus.
Classical Swine Fever
Mutational analysis of the GDD sequence motif of classical swine fever virus RNA-dependent RNA polymerases.
Classical Swine Fever
Phylogenetic comparison and molecular epidemiology of classical swine fever virus.
Classical Swine Fever
Porcine Mx1 Protein Inhibits Classical Swine Fever Virus Replication by Targeting Nonstructural Protein NS5B.
Classical Swine Fever
Processing of pestivirus polyprotein: cleavage site between autoprotease and nucleocapsid protein of classical swine fever virus.
Classical Swine Fever
Rapid detection of classical swine fever virus by a portable real-time reverse transcriptase PCR assay.
Classical Swine Fever
Real-time SPR characterization of the interactions between multi-epitope proteins and antibodies against classical swine fever virus.
Classical Swine Fever
RNA-dependent RNA polymerase activity of Classical swine fever virus NS5B protein expressed in natural host cells.
Classical Swine Fever
Selective stimulation of hepatitis C virus and pestivirus NS5B RNA polymerase activity by GTP.
Classical Swine Fever
Specific interaction between the classical swine fever virus NS5B protein and the viral genome.
Classical Swine Fever
The GTP binding sites interacted with RNA-dependent RNA polymerase of classical swine fever virus in de novo initiation.
Classical Swine Fever
The Network of Interactions Between Classical Swine Fever Virus Nonstructural Protein p7 and Host Proteins.
Classical Swine Fever
The RNA-dependent RNA polymerases of different members of the family Flaviviridae exhibit similar properties in vitro.
Classical Swine Fever
[A new enzyme immunoassay for the detection of antibodies against the bovine viral diarrhea virus]
Cleft Palate
The RNA-binding landscape of RBM10 and its role in alternative splicing regulation in models of mouse early development.
Clostridium Infections
Characterization of a Sugar-O-methyltransferase TiaS5 Affords New Tiacumicin Analogues with Improved Antibacterial Properties and Reveals Substrate Promiscuity.
Clostridium Infections
Fidaxomicin: Difimicin; Lipiarmycin; OPT 80; OPT-80; PAR 101; PAR-101.
Cockayne Syndrome
Deficiency of the Cockayne syndrome B (CSB) gene aggravates the genomic instability caused by endogenous oxidative DNA base damage in mice.
Cockayne Syndrome
Nucleotide excision repair and its interplay with transcription.
Cockayne Syndrome
Oxidatively damaged DNA repair defect in cockayne syndrome and its complementation by heterologous repair proteins.
Cockayne Syndrome
The Cockayne syndrome B protein, involved in transcription-coupled DNA repair, resides in an RNA polymerase II-containing complex.
Coinfection
Biological and Molecular Characteristics of a Novel Partitivirus Infecting the Edible Fungus Lentinula edodes.
Coinfection
Dengue virus and antiplatelet autoantibodies synergistically induce haemorrhage through Nlrp3-inflammasome and Fc?RIII.
Coinfection
Detection and characterization of astroviruses in dogs.
Coinfection
Diversity of the hepatitis C virus NS5B gene during HIV co-infection.
Coinfection
Emergence of unique variants and inter-genotype recombinants of human astroviruses infecting infants, children and adults in Kolkata, India.
Coinfection
Enzyme-linked immunosorbent assay specific to Dengue virus type 1 nonstructural protein NS1 reveals circulation of the antigen in the blood during the acute phase of disease in patients experiencing primary or secondary infections.
Coinfection
Feline calicivirus VP2 is involved in the self-assembly of the capsid protein into virus-like particles.
Coinfection
First Detection of Bat Astroviruses (BtAstVs) among Bats in Poland: The Genetic BtAstVs Diversity Reveals Multiple Co-Infection of Bats with Different Strains.
Coinfection
First Report of Cucurbit Chlorotic Yellows Virus affecting Watermelon in USA.
Coinfection
Genetic variation and recombination of RdRp and HSP 70h genes of Citrus tristeza virus isolates from orange trees showing symptoms of citrus sudden death disease.
Coinfection
Impact of Two Reoviruses and Their Coinfection on the Rice RNAi System and vsiRNA Production.
Coinfection
Production and characterization of monospecific and bispecific antibodies against dengue virus NS1 protein.
Coinfection
The First Identified Citrus tristeza virus Isolate of Turkey Contains a Mixture of Mild and Severe Strains.
Coinfection
Virion-associated transcriptase activity of influenza recombinant and mutant strains.
Colitis, Ulcerative
Human antigen R (HuR) and Cold inducible RNA-binding protein (CIRP) influence intestinal mucosal barrier function in ulcerative colitis by competitive regulation on Claudin1.
Colitis, Ulcerative
Identification of beta-subunit of bacterial RNA-polymerase--a non-species-specific bacterial protein--as target of antibodies in primary biliary cirrhosis.
Colonic Neoplasms
Blocking the IGF2BP1-promoted glucose metabolism of colon cancer cells via direct de-stabilizing mRNA of the LDHA enhances anticancer effects.
Colonic Neoplasms
CBX8 acts as an independent RNA-binding protein to regulate the maturation of miR-378a-3p in colon cancer cells.
Colonic Neoplasms
Editorial retraction. Down-regulation of human telomerase reverse transcriptase through anti-c-myc siRNA in human colon cancer Colo 320 cells.
Colonic Neoplasms
Expression of oncofetal RNA-binding protein CRD-BP/IMP1 predicts clinical outcome in colon cancer.
Colonic Neoplasms
Expression of RNA-binding Motif Protein 3 (
Colonic Neoplasms
Identification of specific modules and significant genes associated with colon cancer by weighted gene co?expression network analysis.
Colonic Neoplasms
LIN28B promotes the progression of colon cancer by increasing B-cell lymphoma 2 expression.
Colonic Neoplasms
LINC00538 promotes the progression of colon cancer through inhibiting NKD2 expression.
Colonic Neoplasms
Natural product (-)-gossypol inhibits colon cancer cell growth by targeting RNA-binding protein Musashi-1.
Colonic Neoplasms
RBMS1 Suppresses Colon Cancer Metastasis through Targeted Stabilization of Its mRNA Regulon.
Colonic Neoplasms
RNA-Binding Protein Quaking, a Critical Regulator of Colon Epithelial Differentiation and a Suppressor of Colon Cancer.
Colonic Neoplasms
The RNA-Binding Protein Musashi1: A Major Player in Intestinal Epithelium Renewal and Colon Cancer Development.
Colonic Neoplasms
The RNA-binding protein RBM3 is required for cell proliferation and protects against serum deprivation-induced cell death.
Colorado Tick Fever
Complete nucleotide sequences of genome segments 1 and 3 of Rosellinia anti-rot virus in the family Reoviridae.
Colorectal Neoplasms
Clinical Significance of Methylation and Reduced Expression of the Quaking Gene in Colorectal Cancer.
Colorectal Neoplasms
Frameshift Mutation of FXR1 Encoding a RNA-Binding Protein in Gastric and Colorectal Cancers with Microsatellite Instability.
Colorectal Neoplasms
High RBM3 expression in prostate cancer independently predicts a reduced risk of biochemical recurrence and disease progression.
Colorectal Neoplasms
HNRNPLL stabilizes mRNA for DNA replication proteins and promotes cell cycle progression in colorectal cancer cells.
Colorectal Neoplasms
HuR regulates cyclin A and cyclin B1 mRNA stability during cell proliferation.
Colorectal Neoplasms
HuR Small-Molecule Inhibitor Elicits Differential Effects in Adenomatosis Polyposis and Colorectal Carcinogenesis.
Colorectal Neoplasms
Increased IGF2BP3 expression promotes the aggressive phenotypes of colorectal cancer cells in vitro and vivo.
Colorectal Neoplasms
Loss of RNA-Binding Protein RBMS1 Promotes a Metastatic Transcriptional Program in Colorectal Cancer.
Colorectal Neoplasms
MicroRNA-24 regulates the growth and chemosensitivity of the human colorectal cancer cells by targeting RNA-binding protein DND1.
Colorectal Neoplasms
MicroRNAs, long noncoding RNAs, and circular RNAs: potential tumor biomarkers and targets for colorectal cancer.
Colorectal Neoplasms
miR-181b functions as an oncomiR in colorectal cancer by targeting PDCD4.
Colorectal Neoplasms
RNA-binding protein CELF1 enhances cell migration, invasion, and chemoresistance by targeting ETS2 in colorectal cancer.
Colorectal Neoplasms
RNA-binding protein IMP3 is a novel regulator of MEK1/ERK signaling pathway in the progression of colorectal Cancer through the stabilization of MEKK1 mRNA.
Colorectal Neoplasms
RNA-Binding Protein Polymorphisms as Novel Biomarkers to Predict Outcomes of Metastatic Colorectal Cancer: A Meta-analysis from TRIBE, FIRE-3, and MAVERICC.
Colorectal Neoplasms
RNA-binding protein RALY reprogrammes mitochondrial metabolism via mediating miRNA processing in colorectal cancer.
Colorectal Neoplasms
RNA-binding protein RBM38 inhibits colorectal cancer progression by partly and competitively binding to PTEN 3'UTR with miR-92a-3p.
Colorectal Neoplasms
RNAi-mediated HuR depletion leads to the inhibition of muscle cell differentiation.
Colorectal Neoplasms
The p53-induced RNA-binding protein ZMAT3 is a splicing regulator that inhibits the splicing of oncogenic CD44 variants in colorectal carcinoma.
Colorectal Neoplasms
The RNA-Binding Protein ESRP1 Modulates the Expression of RAC1b in Colorectal Cancer Cells.
Colorectal Neoplasms
The RNA-binding protein ESRP1 promotes human colorectal cancer progression.
Colorectal Neoplasms
The RNA-Binding Protein HuR Confers Oxaliplatin Resistance of Colorectal Cancer By Upregulating CDC6.
Common Cold
Biochemical characterization of rhinovirus RNA-dependent RNA polymerase.
Common Cold
Combined in silico and in vitro approaches identified the antipsychotic drug lurasidone and the antiviral drug elbasvir as SARS-CoV2 and HCoV-OC43 inhibitors.
Common Cold
The crystal structure of the RNA-dependent RNA polymerase from human rhinovirus: a dual function target for common cold antiviral therapy.
Communicable Diseases
Approved Antiviral Drugs over the Past 50 Years.
Communicable Diseases
Epidemiologic applications of novel molecular methods to detect and differentiate small round structured viruses (Norwalk-like viruses).
Communicable Diseases
Lost in transcription--inhibition of RNA polymerase.
Communicable Diseases
Messenger RNA Vaccines: Beckoning of a New Era in Cancer Immunotherapy.
Communicable Diseases
Q63, a novel DENV2 RdRp non-nucleoside inhibitor, inhibited DENV2 replication and infection.
Communicable Diseases
Serological Differences after Acute Zika Virus Infections between Children and Adults: Implication for Use of a Serological Test.
Communicable Diseases, Emerging
Expression of vector-based small interfering RNA against West Nile virus effectively inhibits virus replication.
Confusion
Tobacco mosaic virus replicase and replicative structures.
Congenital Abnormalities
GroEL is involved in activation of Escherichia coli RNA polymerase devoid of the omega subunit in vivo.
Connective Tissue Diseases
The long-term outcome of interstitial lung disease with anti-aminoacyl-tRNA synthetase antibodies.
Coronavirus Infections
A25?Phylogenetic analysis of the nucleocapsid and RNA-dependent RNA polymerase fragments of the first imported case of middle east respiratory syndrome coronavirus (MERS-CoV) infection in the Philippines from Saudi Arabia, February 2015.
Coronavirus Infections
Alpha and lineage C betaCoV infections in Italian bats.
Coronavirus Infections
Coronavirus infectious bronchitis virus non-structural proteins 8 and 12 form stable complex independent of the non-translated regions of viral RNA and other viral proteins.
Coronavirus Infections
Current approaches for target-specific drug discovery using natural compounds against SARS-CoV-2 infection.
Coronavirus Infections
Lycorine, a non-nucleoside RNA dependent RNA polymerase inhibitor, as potential treatment for emerging coronavirus infections.
Coronavirus Infections
Middle East Respiratory Syndrome Coronavirus 4a Protein Is a Double-Stranded RNA-Binding Protein That Suppresses PACT-Induced Activation of RIG-I and MDA5 in the Innate Antiviral Response.
Coronavirus Infections
NeoCoV Is Closer to MERS-CoV than SARS-CoV.
Coronavirus Infections
On the molecular structure of Remdesivir for the treatment of Covid-19.
Coronavirus Infections
Pharmacological Therapeutics Targeting RNA-Dependent RNA Polymerase, Proteinase and Spike Protein: From Mechanistic Studies to Clinical Trials for COVID-19.
Coronavirus Infections
RNA-dependent RNA polymerase of SARS-CoV-2 as a therapeutic target.
Coronavirus Infections
SARS-CoV-2 RdRp Inhibitors Selected from a Cell-Based SARS-CoV-2 RdRp Activity Assay System.
Coronavirus Infections
The antiviral compound remdesivir potently inhibits RNA-dependent RNA polymerase from Middle East respiratory syndrome coronavirus.
Coronavirus Infections
The potential chemical structure of anti-SARS-CoV-2 RNA-dependent RNA polymerase.
Coronavirus Infections
Whole Genome Analysis and Targeted Drug Discovery Using Computational Methods and High Throughput Screening Tools for Emerged Novel Coronavirus (2019-nCoV).
Cough
A randomized and comparative study to assess safety and efficacy of supplemental treatment of a herbal formulation - Aayudh Advance comprising essential oils in patients with corona virus 2019 (COVID-19).
Cough
SARS-CoV-2 Infection and Antibody Response in a Symptomatic Cat from Italy with Intestinal B-Cell Lymphoma.
COVID-19
"Bucket brigade" using lysine residues in RNA-dependent RNA polymerase of SARS-CoV-2.
COVID-19
A cell-based assay to discover inhibitors of SARS-CoV-2 RNA dependent RNA polymerase.
COVID-19
A computational analysis of molecular evolution for virulence genes of zoonotic novel coronavirus (COVID-19).
COVID-19
A multiple peptides vaccine against COVID-19 designed from the nucleocapsid phosphoprotein (N) and Spike Glycoprotein (S) via the immunoinformatics approach.
COVID-19
A nanoscale genosensor for early detection of COVID-19 by voltammetric determination of RNA-dependent RNA polymerase (RdRP) sequence of SARS-CoV-2 virus.
COVID-19
Acetylcysteine for the Treatment of Suspected Remdesivir-Associated Acute Liver Failure in COVID-19: A Case Series.
COVID-19
An in silico approach for identification of novel inhibitors as potential therapeutics targeting COVID-19 main protease.
COVID-19
An in silico approach to target RNA-dependent RNA polymerase of COVID-19 with naturally occurring phytochemicals.
COVID-19
Anisotine and amarogentin as promising inhibitory candidates against SARS-CoV-2 proteins: a computational investigation.
COVID-19
Anti-HCV, nucleotide inhibitors, repurposing against COVID-19.
COVID-19
Antiviral effects of probiotic metabolites on COVID-19.
COVID-19
Are clarithromycin, azithromycin and their analogues effective in the treatment of COVID19?
COVID-19
Association Between ABO and Rh Blood Groups and SARS-CoV-2 Infection or Severe COVID-19 Illness : A Population-Based Cohort Study.
COVID-19
AVIFAVIR for Treatment of Patients With Moderate Coronavirus Disease 2019 (COVID-19): Interim Results of a Phase II/III Multicenter Randomized Clinical Trial.
COVID-19
Baicalein and Baicalin Inhibit SARS-CoV-2 RNA-Dependent-RNA Polymerase.
COVID-19
Binding mechanism and structural insights into the identified protein target of COVID-19 and importin-? with in-vitro effective drug ivermectin.
COVID-19
C60 fullerene against SARS-CoV-2 coronavirus: an in silico insight.
COVID-19
Can mesenchymal stem cell therapy be the interim management of COVID-19?
COVID-19
Chemical composition and pharmacological mechanism of shenfu decoction in the treatment of novel coronavirus pneumonia (COVID-19).
COVID-19
Clinical Efficacy of Remdesivir and Favipiravir in the Treatment of Covid-19 Patients: Scenario So Far.
COVID-19
Clinical profile, viral load, management and outcome of neonates born to COVID 19 positive mothers: a tertiary care centre experience from India.
COVID-19
Combination of QSAR, molecular docking, molecular dynamic simulation and MM-PBSA: analogues of lopinavir and favipiravir as potential drug candidates against COVID-19.
COVID-19
Combining SARS-CoV-2 Proofreading Exonuclease and RNA-Dependent RNA Polymerase Inhibitors as a Strategy to Combat COVID-19: A High-Throughput in silico Screening.
COVID-19
Comparative Evaluation of Tears and Nasopharyngeal Swab for SARS-CoV-2 in COVID-19 Dedicated Intensive Care Unit Patients.
COVID-19
Comprehensive Virtual Screening of the Antiviral Potentialities of Marine Polycyclic Guanidine Alkaloids against SARS-CoV-2 (COVID-19).
COVID-19
Computational investigation for identification of potential phytochemicals and antiviral drugs as potential inhibitors for RNA-dependent RNA polymerase of COVID-19.
COVID-19
Corilagin inhibits SARS-CoV-2 replication by targeting viral RNA-dependent RNA polymerase.
COVID-19
Current targets and drug candidates for prevention and treatment of SARS-CoV-2 (COVID-19) infection.
COVID-19
Cyanorona-20: The first potent anti-SARS-CoV-2 agent.
COVID-19
Delayed Development of Coronary Artery Dilitation in Suspected Severe Acute Respiratory Syndrome Coronavirus 2 Multisystem Inflammatory Syndrome: More Research Needed.
COVID-19
Denovo designing, retro-combinatorial synthesis, and molecular dynamics analysis identify novel antiviral VTRM1.1 against RNA-dependent RNA polymerase of SARS CoV2 virus.
COVID-19
Design and in-silico screening of Peptide Nucleic Acid (PNA) inspired novel pronucleotide scaffolds targeting COVID-19.
COVID-19
Detection and quantification of SARS-CoV-2 by droplet digital PCR in real-time PCR negative nasopharyngeal swabs from suspected COVID-19 patients.
COVID-19
Determination of human COVID-19 total antibodies in serum using a time-resolved fluorescence immunoassay.
COVID-19
Development of a Smartphone-Based Nanozyme-Linked Immunosorbent Assay for Quantitative Detection of SARS-CoV-2 Nucleocapsid Phosphoprotein in Blood.
COVID-19
Development of remdesivir repositioning as a nucleotide analog against COVID-19 RNA dependent RNA polymerase.
COVID-19
Different selection dynamics of S and RdRp between SARS-CoV-2 genomes with and without the dominant mutations.
COVID-19
Discovering Potential RNA Dependent RNA Polymerase Inhibitors as Prospective Drugs Against COVID-19: An in silico Approach.
COVID-19
Discovery of (E)-N-(4-cyanobenzylidene)- 6-fluoro- 3-hydroxypyrazine-2 -carboxamide (cyanorona-20): the first potent and specific anti-COVID-19 drug.
COVID-19
Discovery of potential multi-target-directed ligands by targeting host-specific SARS-CoV-2 structurally conserved main protease.
COVID-19
Dynamic properties of SARS-CoV and SARS-CoV-2 RNA-dependent RNA polymerases studied by molecular dynamics simulations.
COVID-19
Efficacy and safety of favipiravir, an oral RNA-dependent RNA polymerase inhibitor, in mild-to-moderate COVID-19: A randomized, comparative, open-label, multicenter, phase 3 clinical trial.
COVID-19
Efficacy and safety of remdesivir in COVID-19 caused by SARS-CoV-2: a systematic review and meta-analysis.
COVID-19
Elucidating the drug repurposing spectra of COVID-19 with its analogues SARS and MERS.
COVID-19
Emergence of Drift Variants That May Affect COVID-19 Vaccine Development and Antibody Treatment.
COVID-19
Emerging SARS-CoV-2 mutation hot spots include a novel RNA-dependent-RNA polymerase variant.
COVID-19
Enisamium is an inhibitor of the SARS-CoV-2 RNA polymerase and shows improvement of recovery in COVID-19 patients in an interim analysis of a clinical trial.
COVID-19
Entropy-driven amplified electrochemiluminescence biosensor for RdRp gene of SARS-CoV-2 detection with self-assembled DNA tetrahedron scaffolds.
COVID-19
Establishing diagnostic algorithms for SARS-CoV-2 nucleic acid testing in clinical practice.
COVID-19
Evaluation of potential anti-RNA-dependent RNA polymerase (RdRP) drugs against the newly emerged model of COVID-19 RdRP using computational methods.
COVID-19
Evaluation of RdRp & ORF-1b-nsp14-based real-time RT-PCR assays for confirmation of SARS-CoV-2 infection: An observational study.
COVID-19
Evaluation on the use of Nanopore sequencing for direct characterization of coronaviruses from respiratory specimens, and a study on emerging missense mutations in partial RdRP gene of SARS-CoV-2.
COVID-19
Evidence of the presence of SARS-CoV-2 virus in atmospheric air and surfaces of a dedicated COVID hospital.
COVID-19
Existing antiviral options against SARS-CoV-2 replication in COVID-19 patients.
COVID-19
Exploiting Existing Molecular Scaffolds for Long-Term COVID Treatment.
COVID-19
Exploring the SARS-CoV-2 main protease (Mpro) and RdRp targets by updating current structure-based drug design utilizing co-crystals to combat COVID-19.
COVID-19
Expression and purification of tag-free SARS-CoV-2 RNA-dependent RNA polymerase in Escherichia coli.
COVID-19
Facilitating SARS CoV-2 RNA-Dependent RNA polymerase (RdRp) drug discovery by the aid of HCV NS5B palm subdomain binders: In silico approaches and benchmarking.
COVID-19
Favipiravir strikes the SARS-CoV-2 at its Achilles heel, the RNA polymerase.
COVID-19
Favipiravir versus other antiviral or standard of care for COVID-19 treatment: a rapid systematic review and meta-analysis.
COVID-19
Fe-S cofactors in the SARS-CoV-2 RNA-dependent RNA polymerase are potential antiviral targets.
COVID-19
Fighting COVID-19: A quick review of diagnoses, therapies, and vaccines.
COVID-19
Genetic Risk Factors for the Development of COVID-19 Coronavirus Infection.
COVID-19
Health Surveillance and Response to SARS-CoV-2 Mass Testing in Health Workers of a Large Italian Hospital in Verona, Veneto.
COVID-19
High-resolution structure and biophysical characterization of the nucleocapsid phosphoprotein dimerization domain from the Covid-19 severe acute respiratory syndrome coronavirus 2.
COVID-19
HISNAPI: a bioinformatic tool for dynamic hot spot analysis in nucleic acid-protein interface with a case study.
COVID-19
Hordatines as a Potential Inhibitor of COVID-19 Main Protease and RNA Polymerase: An In-Silico Approach.
COVID-19
Identification and characterization of mutations in the SARS-CoV-2 RNA-dependent RNA polymerase as a promising antiviral therapeutic target.
COVID-19
Identification of a novel dual-target scaffold for 3CLpro and RdRp proteins of SARS-CoV-2 using 3D-similarity search, molecular docking, molecular dynamics and ADMET evaluation.
COVID-19
Identification of nsp1 gene as the target of SARS-CoV-2 real-time RT-PCR using nanopore whole-genome sequencing.
COVID-19
Identification of Potential Key Agents for Targeting RNA-Dependent RNA Polymerase of SARS-CoV-2 by Integrated Analysis and Virtual Drug Screening.
COVID-19
Implications of SARS-CoV-2 genetic diversity and mutations on pathogenicity of the COVID-19 and biomedical interventions.
COVID-19
Improved sensitivity using a dual target, E and RdRp assay for the diagnosis of SARS-CoV-2 infection: Experience at a large NHS Foundation Trust in the UK.
COVID-19
In silico identification of promising inhibitor against RNA-dependent RNA polymerase target of SARS-CoV-2.
COVID-19
In silico screening of hundred phytocompounds of ten medicinal plants as potential inhibitors of nucleocapsid phosphoprotein of COVID-19: an approach to prevent virus assembly.
COVID-19
In silico studies on therapeutic agents for COVID-19: Drug repurposing approach.
COVID-19
Interface-based design of the favipiravir-binding site in SARS-CoV-2 RNA-dependent RNA polymerase reveals mutations conferring resistance to chain termination.
COVID-19
Interpret with caution: An evaluation of the commercial AusDiagnostics versus in-house developed assays for the detection of SARS-CoV-2 virus.
COVID-19
Investigating the Internalization and COVID-19 Antiviral Computational Analysis of Optimized Nanoscale Zinc Oxide.
COVID-19
Is there a correlation between viral load and olfactory & taste dysfunction in COVID-19 patients?
COVID-19
Is there a link between lung parenchyma lesions , BMI , CRP , D-dimer and acute pulmonary embolism in patients infected with COVID-19 ?
COVID-19
Letter to the editor on "Efficacy and safety of favipiravir, an oral RNA-dependent RNA polymerase inhibitor, in mild-to-moderate COVID-19: A randomized, comparative, open-label, multicenter, phase 3 clinical trial" by Udwadia et al.
COVID-19
Lung transcriptome of a COVID-19 patient and systems biology predictions suggest impaired surfactant production which may be druggable by surfactant therapy.
COVID-19
Lycorine, a non-nucleoside RNA dependent RNA polymerase inhibitor, as potential treatment for emerging coronavirus infections.
COVID-19
Metabolomic profiling of three Araucaria species, and their possible potential role against COVID-19.
COVID-19
Molecular detection of SARS-CoV-2 from indoor air samples in environmental monitoring needs adequate temporal coverage and infectivity assessment.
COVID-19
Molecular docking and dynamics studies of Nicotinamide Riboside as a potential multi-target nutraceutical against SARS-CoV-2 entry, replication, and transcription: A new insight.
COVID-19
Molecular dynamics simulation, 3D-pharmacophore and scaffold hopping analysis in the design of multi-target drugs to inhibit potential targets of COVID-19.
COVID-19
Molecular modelling of the antiviral action of Resveratrol derivatives against the activity of two novel SARS CoV-2 and 2019-nCoV receptors.
COVID-19
Molecular targets for COVID-19 drug development: Enlightening Nigerians about the pandemic and future treatment.
COVID-19
Molnupiravir promotes SARS-CoV-2 mutagenesis via the RNA template.
COVID-19
N-acetylcysteine (NAC) and Hydrogen Sulfide (H2S) in Coronavirus Disease 2019 (COVID-19).
COVID-19
New-Onset IgG Autoantibodies in Hospitalized Patients with COVID-19.
COVID-19
Nonstructural Protein 1 of SARS-CoV-2 Is a Potent Pathogenicity Factor Redirecting Host Protein Synthesis Machinery toward Viral RNA.
COVID-19
Novel Development of Predictive Feature Fingerprints to Identify Chemistry-Based Features for the Effective Drug Design of SARS-CoV-2 Target Antagonists and Inhibitors Using Machine Learning.
COVID-19
Nucleotide Analogues as Inhibitors of SARS-CoV-2 Polymerase, a Key Drug Target for COVID-19.
COVID-19
On the molecular structure of Remdesivir for the treatment of Covid-19.
COVID-19
One-Step Quantitative RT-PCR Assay with Armored RNA Controls for Detection of SARS-CoV-2.
COVID-19
Peptides: Prospects for Use in the Treatment of COVID-19.
COVID-19
Persistent Smell Loss Following Undetectable SARS-CoV-2.
COVID-19
Pharmacological Therapeutics Targeting RNA-Dependent RNA Polymerase, Proteinase and Spike Protein: From Mechanistic Studies to Clinical Trials for COVID-19.
COVID-19
Plant-derived natural polyphenols as potential antiviral drugs against SARS-CoV-2 via RNA-dependent RNA polymerase (RdRp) inhibition: an in-silico analysis.
COVID-19
Poliovirus Vaccination Induces a Humoral Immune Response That Cross Reacts With SARS-CoV-2.
COVID-19
Potential Candidates against COVID-19 Targeting RNA-Dependent RNA Polymerase: A Comprehensive Review.
COVID-19
Potential RNA-dependent RNA polymerase inhibitors as prospective therapeutics against SARS-CoV-2.
COVID-19
Potential therapeutic targets for combating SARS-CoV-2: Drug repurposing, clinical trials and recent advancements.
COVID-19
Practical Remdesivir Synthesis through One-Pot Organocatalyzed Asymmetric (S)-P-Phosphoramidation.
COVID-19
Prediction of potential inhibitors for RNA-dependent RNA polymerase of SARS-CoV-2 using comprehensive drug repurposing and molecular docking approach.
COVID-19
Quantitative Structure-Activity Relationship Machine Learning Models and their Applications for Identifying Viral 3CLpro- and RdRp-Targeting Compounds as Potential Therapeutics for COVID-19 and Related Viral Infections.
COVID-19
Quinolines-Based SARS-CoV-2 3CLpro and RdRp Inhibitors and Spike-RBD-ACE2 Inhibitor for Drug-Repurposing Against COVID-19: An in silico Analysis.
COVID-19
Raltegravir, Indinavir, Tipranavir, Dolutegravir, and Etravirine against main protease and RNA-dependent RNA polymerase of SARS-CoV-2: A molecular docking and drug repurposing approach.
COVID-19
Rapid Diagnosis of Coronavirus by RNA-Directed RNA Transcription Using an Engineered RNA-based Platform.
COVID-19
Rapid incorporation of Favipiravir by the fast and permissive viral RNA polymerase complex results in SARS-CoV-2 lethal mutagenesis.
COVID-19
Recent advances in the discovery of potent RNA-dependent RNA-polymerase (RdRp) inhibitors targeting viruses.
COVID-19
Remdesivir failure with SARS-CoV-2 RNA-dependent RNA-polymerase mutation in a B-cell immunodeficient patient with protracted Covid-19.
COVID-19
Remdesivir for 5 or 10 Days in Patients with Severe Covid-19.
COVID-19
Remdesivir Is Effective in Combating COVID-19 because It Is a Better Substrate than ATP for the Viral RNA-Dependent RNA Polymerase.
COVID-19
Remdesivir Strongly Binds to Both RNA-Dependent RNA Polymerase and Main Protease of SARS-CoV-2: Evidence from Molecular Simulations.
COVID-19
Remdesivir Treatment for COVID 19 in Pregnant Patients with Moderate to Severe Symptoms: Serial Case Report.
COVID-19
Repositioning HIV protease inhibitors and nucleos(t)ide RNA polymerase inhibitors for the treatment of SARS-CoV-2 infection and COVID-19.
COVID-19
Repurposing FDA-approved drugs to fight COVID-19 using in silico methods: Targeting SARS-CoV-2 RdRp enzyme and host cell receptors (ACE2, CD147) through virtual screening and molecular dynamic simulations.
COVID-19
Repurposing FDA-approved phytomedicines, natural products, antivirals and cell protectives against SARS-CoV-2 (COVID-19) RNA-dependent RNA polymerase.
COVID-19
Response to the comments received on article "Efficacy and safety of favipiravir, an oral RNA-dependent RNA polymerase inhibitor, in mild-to-moderate COVID-19: A randomized, comparative, open-label, multicenter, phase 3 clinical trial" by Udwadia et al.
COVID-19
Revealing the Inhibition Mechanism of RNA-Dependent RNA Polymerase (RdRp) of SARS-CoV-2 by Remdesivir and Nucleotide Analogues: A Molecular Dynamics Simulation Study.
COVID-19
RNA-dependent RNA polymerase (RdRp) inhibitors: The current landscape and repurposing for the COVID-19 pandemic.
COVID-19
RNA-Dependent RNA Polymerase as a Target for COVID-19 Drug Discovery.
COVID-19
RNA-dependent RNA polymerase, RdRP, a promising therapeutic target for cancer and potentially COVID-19.
COVID-19
RNA-dependent RNA polymerase: Structure, mechanism, and drug discovery for COVID-19.
COVID-19
RT-qPCR Diagnostics: The "Drosten" SARS-CoV-2 Assay Paradigm.
COVID-19
SARS-CoV-2 and miRNA-like inhibition power.
COVID-19
SARS-CoV-2 Nonstructural Protein 1 Inhibits the Interferon Response by Causing Depletion of Key Host Signaling Factors.
COVID-19
SARS-CoV-2 Nsp1 suppresses host but not viral translation through a bipartite mechanism.
COVID-19
SARS-CoV-2 NSP12 Protein Is Not an Interferon-? Antagonist.
COVID-19
SARS-CoV-2 orf1b Gene Sequence in the NTNG1 Gene on Human Chromosome 1.
COVID-19
SARS-CoV-2 RdRp Inhibitors Selected from a Cell-Based SARS-CoV-2 RdRp Activity Assay System.
COVID-19
SARS-CoV-2 RNA dependent RNA polymerase (RdRp) targeting: an in silico perspective.
COVID-19
SARS-CoV-2 RNA-dependent RNA polymerase as a therapeutic target for COVID-19.
COVID-19
SARS-CoV-2 Treatment Approaches: Numerous Options, No Certainty for a Versatile Virus.
COVID-19
SARS-CoV-2: Origin, Evolution, and Targeting Inhibition.
COVID-19
Screening and Molecular Modeling Evaluation of Food Peptides to Inhibit Key Targets of COVID-19 Virus.
COVID-19
Screening of drug databank against WT and mutant main protease of SARS-CoV-2: Towards finding potential compound for repurposing against COVID-19.
COVID-19
Screening of potent drug inhibitors against SARS-CoV-2 RNA polymerase: an in silico approach.
COVID-19
Second Episode of COVID-19 in Health Professionals: Report of Two Cases.
COVID-19
Severe acute respiratory illness surveillance for coronavirus disease 2019, India, 2020.
COVID-19
Sewage surveillance for the presence of SARS-CoV-2 genome as a useful wastewater based epidemiology (WBE) tracking tool in India.
COVID-19
Sinus Bradycardia in a Pediatric Patient Treated With Remdesivir for Acute Coronavirus Disease 2019: A Case Report and a Review of the Literature.
COVID-19
Spike protein D614G and RdRp P323L: the SARS-CoV-2 mutations associated with severity of COVID-19.
COVID-19
Status of Health-care Workers in Relation to COVID-19 Infection: A Retrospective Study in a Level 4 COVID Hospital in Eastern India.
COVID-19
Structural Basis for RNA Replication by the SARS-CoV-2 Polymerase.
COVID-19
Structural Insights into the Binding Modes of Viral RNA-Dependent RNA Polymerases Using a Function-Site Interaction Fingerprint Method for RNA Virus Drug Discovery.
COVID-19
Structure of the RNA-dependent RNA polymerase from COVID-19 virus.
COVID-19
Systematic duplex ultrasound screening in conventional units for COVID-19 patients with follow-up of 5 days.
COVID-19
Targeting SARS-CoV-2 RNA-dependent RNA polymerase: An in silico drug repurposing for COVID-19.
COVID-19
Targeting Viral RNA-Dependent RNA Polymerases as an Antiviral Therapy.
COVID-19
The anti-HCV, Sofosbuvir, versus the anti-EBOV Remdesivir against SARS-CoV-2 RNA dependent RNA polymerase in silico.
COVID-19
The Binding of Remdesivir to SARS-CoV-2 RNA-Dependent RNA Polymerase May Pave The Way Towards the Design of Potential Drugs for COVID-19 Treatment.
COVID-19
The Computational Intervention of Macrolide Antibiotics in the Treatment of COVID-19.
COVID-19
The Current Recommended Drugs and Strategies for the Treatment of Coronavirus Disease (COVID-19).
COVID-19
The main protease and RNA-dependent RNA polymerase are two prime targets for SARS-CoV-2.
COVID-19
The molecular assessment of SARS-CoV-2 Nucleocapsid Phosphoprotein variants among Indian isolates.
COVID-19
The Promising Enzymes for Inhibitors Development against COVID-19.
COVID-19
Therapeutic management of COVID-19 patients: Clinical manifestation and limitations.
COVID-19
Time Length of Negativization and Cycle Threshold Values in 182 Healthcare Workers with Covid-19 in Milan, Italy: An Observational Cohort Study.
COVID-19
TMPRSS2 and RNA-Dependent RNA Polymerase Are Effective Targets of Therapeutic Intervention for Treatment of COVID-19 Caused by SARS-CoV-2 Variants (B.1.1.7 and B.1.351).
COVID-19
Treatment options for COVID-19: The reality and challenges.
COVID-19
Variable effects of underlying diseases on the prognosis of patients with COVID-19.
COVID-19
Viral Load Difference between Symptomatic and Asymptomatic COVID-19 Patients: Systematic Review and Meta-Analysis.
COVID-19
[Comparison of Real Time PCR Cycle Threshold Values in Symptomatic and Asymptomatic COVID-19 Patients].
COVID-19
[Promising and potential drugs for the treatment of COVID-19].
COVID-19
[The use of viral RNA polymerase inhibitors in combination with a fusion inhibitor in the treatment of patients with COVID-19: hypothesis].
Cowpox
Fine structure mapping and phenotypic analysis of five temperature-sensitive mutations in the second largest subunit of vaccinia virus DNA-dependent RNA polymerase.
Cowpox
Post-transcription cleavage generates the 3' end of F17R transcripts in vaccinia virus.
Crohn Disease
Identification of beta-subunit of bacterial RNA-polymerase--a non-species-specific bacterial protein--as target of antibodies in primary biliary cirrhosis.
Cryptorchidism
Association between RNA-binding protein Ptbp2 and germ cell injury in an experimentally-induced unilateral cryptorchidism murine model.
Cryptorchidism
Downregulation of cold-inducible RNA-binding protein activates mitogen-activated protein kinases and impairs spermatogenic function in mouse testes.
Cryptorchidism
Effects of cold-inducible RNA-binding protein on the proliferation and apoptosis of spermatogenic cells invitro following heat stress.
Cryptorchidism
Overexpression of CIRP may reduce testicular damage induced by cryptorchidism.
Cystic Fibrosis
Discovery of Ubonodin, an Antimicrobial Lasso Peptide Active against Members of the Burkholderia cepacia Complex.
Cystic Fibrosis
Secretory low-molecular-weight phospholipases A2 and their specific receptor in bile ducts of patients with intrahepatic calculi: factors of chronic proliferative cholangitis.
Cysts
Arabidopsis small RNAs and their targets during cyst nematode parasitism.
Cysts
Bicaudal C, a novel regulator of Dvl signaling abutting RNA-processing bodies, controls cilia orientation and leftward flow.
Cysts
Levels of RNA polymerase activities during growth, encystment and germination ofPhysarum polycephalum.
Cytomegalovirus Infections
Approved Antiviral Drugs over the Past 50 Years.
Cytomegalovirus Infections
Detection of active cytomegalovirus infection in inflammatory aortic aneurysms with RNA polymerase chain reaction.
Cytomegalovirus Infections
Regarding "Detection of active cytomegalovirus infection in inflammatory aortic aneurysms with RNA polymerase chain reaction".
Cytomegalovirus Retinitis
[Cytomegalovirus retinitis in pediatric patients with AIDS receiving highly active antiretrovirus therapy]
Decompression Sickness
A comprehensive alanine scanning mutagenesis of the Escherichia coli transcriptional activator SoxS: identifying amino acids important for DNA binding and transcription activation.
Decompression Sickness
Involvement of the global Crp regulator in cyclic AMP-dependent utilization of aromatic amino acids by Pseudomonas putida.
Decompression Sickness
Maximal transcriptional activation by the IHF protein of Escherichia coli depends on optimal DNA bending by the activator.
Decompression Sickness
Mesoscale modeling of multi-protein-DNA assemblies: the role of the catabolic activator protein in Lac-repressor-mediated looping.
Decompression Sickness
Participation of IHF and a distant UP element in the stimulation of the phage lambda PL promoter.
Decompression Sickness
Transcriptional activation of promoters of the superoxide and multiple antibiotic resistance regulons by Rob, a binding protein of the Escherichia coli origin of chromosomal replication.
Dehydration
Conformational coupling, bridge helix dynamics and active site dehydration in catalysis by RNA polymerase.
Dehydration
Incidence and predictive factors of transaminase elevation in patients consulting for dengue fever in Cayenne Hospital, French Guiana.
Dementia
ALS/FTLD-Linked Mutations in FUS Glycine Residues Cause Accelerated Gelation and Reduced Interactions with Wild-Type FUS.
Dementia
An Amyloid-Like Pathological Conformation of TDP-43 Is Stabilized by Hypercooperative Hydrogen Bonds.
Dementia
An optimized InCell Western screening technique identifies hexachlorophene as a novel potent TDP43 targeting drug.
Dementia
Cdc37/Hsp90 protein complex disruption triggers an autophagic clearance cascade for TDP-43 protein.
Dementia
Expression of Fused in sarcoma mutations in mice recapitulates the neuropathology of FUS proteinopathies and provides insight into disease pathogenesis.
Dementia
Myo-granules Connect Physiology and Pathophysiology.
Dementia
Neurotoxic effects of TDP-43 overexpression in C. elegans.
Dementia
Restoration of motor defects caused by loss of Drosophila TDP-43 by expression of the voltage-gated calcium channel, Cacophony, in central neurons.
Dementia
S-nitrosylated TDP-43 triggers aggregation, cell-to-cell spread, and neurotoxicity in hiPSCs and in vivo models of ALS/FTD.
Dementia
Structural basis for RNA recognition by the N-terminal tandem RRM domains of human RBM45.
Dementia
The neuronal RNA-binding protein Nova-2 is implicated as the autoantigen targeted in POMA patients with dementia.
Demyelinating Diseases
miRNA-Coordinated Schizophrenia Risk Network Cross-Talk With Cardiovascular Repair and Opposed Gliomagenesis.
Demyelinating Diseases
Transgenic Expression of the 3D Polymerase Inhibits Theiler's Virus Infection and Demyelination.
Dengue
A 5' RNA element promotes dengue virus RNA synthesis on a circular genome.
Dengue
A Conserved Pocket in the Dengue Virus Polymerase Identified through Fragment-based Screening.
Dengue
A Critical Role for Perivascular Cells in Amplifying Vascular Leakage Induced by Dengue Virus Nonstructural Protein 1.
Dengue
A crystal structure of the Dengue virus NS5 polymerase delineates inter-domain amino acids residues that enhance its thermostability and de novo initiation activities.
Dengue
A crystal structure of the Dengue virus NS5 protein reveals a novel inter-domain interface essential for protein flexibility and virus replication.
Dengue
A fluorescence-based alkaline phosphatase-coupled polymerase assay for identification of inhibitors of dengue virus RNA-dependent RNA polymerase.
Dengue
A multi-step strategy to obtain crystals of the dengue virus RNA-dependent RNA polymerase that diffract to high resolution.
Dengue
A novel interaction between dengue virus nonstructural protein 1 and the NS4A-2K-4B precursor is required for viral RNA replication but not for formation of the membranous replication organelle.
Dengue
A Review on the Progress and Prospects of Dengue Drug Discovery Targeting NS5 RNA- Dependent RNA Polymerase.
Dengue
A single amino acid in nonstructural protein NS4B confers virulence to dengue virus in AG129 mice through enhancement of viral RNA synthesis.
Dengue
A small region of the dengue virus-encoded RNA-dependent RNA polymerase, NS5, confers interaction with both the nuclear transport receptor importin-beta and the viral helicase, NS3.
Dengue
A structural view of the RNA-dependent RNA polymerases from the Flavivirus genus.
Dengue
A T164S mutation in the dengue virus NS1 protein is associated with greater disease severity in mice.
Dengue
Alkylated flavanones from the bark of Cryptocarya chartacea as dengue virus NS5 polymerase inhibitors.
Dengue
An antigen capture enzyme-linked immunosorbent assay reveals high levels of the dengue virus protein NS1 in the sera of infected patients.
Dengue
An In-Silico Investigation of Phytochemicals as Antiviral Agents against Dengue Fever.
Dengue
An N-Terminal Amphipathic Helix in Dengue Virus Nonstructural Protein 4A Mediates Oligomerization and Is Essential for Replication.
Dengue
Analysis of the virus propagation profile of 14 dengue virus isolates in Aedes albopictus C6/36 cells.
Dengue
Anti-dengue virus nonstructural protein 1 antibodies contribute to platelet phagocytosis by macrophages.
Dengue
Anti-dengue virus nonstructural protein 1 antibodies recognize protein disulfide isomerase on platelets and inhibit platelet aggregation.
Dengue
Antibodies against nonstructural protein 1 protect mice from dengue virus-induced mast cell activation.
Dengue
Antibodies from dengue patient sera cross-react with endothelial cells and induce damage.
Dengue
Application of antibodies against nonstructural protein 2B of dengue serotype 2 virus induced by DNA immunisation or recombinant protein NS 2B immunisation in BALB/c mice.
Dengue
Approach to non-invasive sampling in dengue diagnostics: exploring virus and NS1 antigen detection in saliva and urine of travelers with dengue.
Dengue
Apropos "Evaluation of dengue nonstructural protein 1 antigen strip for the rapid diagnosis of patients with dengue infection"
Dengue
Association between NS3 and NS5 proteins of dengue virus type 2 in the putative RNA replicase is linked to differential phosphorylation of NS5.
Dengue
Betulinic acid, the first lupane-type triterpenoid isolated from both a Phomopsis sp. and its host plant Diospyros carbonaria Benoist.
Dengue
Beyond Members of the Flaviviridae Family, Sofosbuvir Also Inhibits Chikungunya Virus Replication.
Dengue
Biflavonoids of Dacrydium balansae with Potent Inhibitory Activity on Dengue 2 NS5 Polymerase.
Dengue
Biochemical characterization of the inhibition of the dengue virus RNA polymerase by beta-d-2'-ethynyl-7-deaza-adenosine triphosphate.
Dengue
Chagas Disease in Southern Coastal Ecuador: Coinfections with Arboviruses and a Comparison of Serological Assays for Chagas Disease Diagnosis.
Dengue
Characterisation of inter- and intra-molecular interactions of the dengue virus RNA dependent RNA polymerase as potential drug targets.
Dengue
Characterization of dengue virus NS1 stably expressed in 293T cell lines.
Dengue
Characterization of soluble RNA-dependent RNA polymerase from dengue virus serotype 2: The polyhistidine tag compromises the polymerase activity.
Dengue
Characterization of the elongation complex of dengue virus RNA polymerase: assembly, kinetics of nucleotide incorporation, and fidelity.
Dengue
Chemical constituents of Anacolosa pervilleana and their antiviral activities.
Dengue
Clinical and Epidemiological Characterization of the First Recognized Outbreak of Dengue Virus-Type 2 in Mozambique, 2014.
Dengue
Clinical and Laboratory Diagnosis of Dengue Virus Infection.
Dengue
Clinical and Laboratory Profile of Zika and Dengue Infected Patients: Lessons Learned From the Co-circulation of Dengue, Zika and Chikungunya in Brazil.
Dengue
Clinical diagnosis of early dengue infection by novel one-step multiplex real-time RT-PCR targeting NS1 gene.
Dengue
Clinical features and outcomes of neonatal dengue at the Children's Hospital 1, Ho Chi Minh, Vietnam.
Dengue
Clinical features and pitfalls in the laboratory diagnosis of dengue in travellers.
Dengue
Coarse-Grained Molecular Modeling of the Solution Structure Ensemble of Dengue Virus Nonstructural Protein 5 with Small-Angle X-ray Scattering Intensity.
Dengue
Coinfection of chikungunya and dengue viruses: A serological study from North Western region of Punjab, India.
Dengue
Combination of Nonstructural Protein 1-Based Enzyme-Linked Immunosorbent Assays Can Detect and Distinguish Various Dengue Virus and Zika Virus Infections.
Dengue
Comparative mechanistic studies of de novo RNA synthesis by flavivirus RNA-dependent RNA polymerases.
Dengue
Comparison of capture immunoglobulin M (IgM) and IgG enzyme-linked immunosorbent assay (ELISA) and nonstructural protein NS1 serotype-specific IgG ELISA for differentiation of primary and secondary dengue virus infections.
Dengue
Comparison of two commercially available dengue virus (DENV) NS1 capture enzyme-linked immunosorbent assays using a single clinical sample for diagnosis of acute DENV infection.
Dengue
Comprehensive mapping of immunodominant and conserved serotype- and group-specific B-cell epitopes of nonstructural protein 1 from dengue virus type 1.
Dengue
Conformational flexibility of the dengue virus RNA-dependent RNA polymerase revealed by a complex with an inhibitor.
Dengue
Construction of recombinant Kluyveromyces marxianus UFV-3 to express dengue virus type 1 nonstructural protein 1 (NS1).
Dengue
Correlation between Serum Levels of Anti-Endothelial Cell Autoantigen and Anti-Dengue Virus Nonstructural Protein 1 Antibodies in Dengue Patients.
Dengue
Critical role of Dengue Virus NS1 protein in viral replication.
Dengue
CRM1-dependent nuclear export of dengue virus type 2 NS5.
Dengue
CRM1-mediated nuclear export of dengue virus RNA polymerase NS5 modulates interleukin-8 induction and virus production.
Dengue
Crystal structure of the dengue virus RNA-dependent RNA polymerase catalytic domain at 1.85-angstrom resolution.
Dengue
Cyclic Dinucleotide-Adjuvanted Dengue Virus Nonstructural Protein 1 Induces Protective Antibody and T Cell Responses.
Dengue
De novo synthesis of negative-strand RNA by Dengue virus RNA-dependent RNA polymerase in vitro: nucleotide, primer, and template parameters.
Dengue
De novo synthesis of RNA by the dengue virus RNA-dependent RNA polymerase exhibits temperature dependence at the initiation but not elongation phase.
Dengue
Deadly intracranial bleed in patients with dengue fever: A series of nine patients and review of literature.
Dengue
Defining the Utility of a Commercial NS1 Antigen Capture Kit as a Dengue Virus (DENV) Diagnostic Tool.
Dengue
Deletion analysis of dengue virus type 4 nonstructural protein NS2B: identification of a domain required for NS2B-NS3 protease activity.
Dengue
Deletion of the C-terminal region of dengue virus nonstructural protein 1 (NS1) abolishes anti-NS1-mediated platelet dysfunction and bleeding tendency.
Dengue
Dengue epidemics in two distinct periods reveal distinct epidemiological, laboratorial and clinical aspects in a same scenario: analysis of the 2010 and 2013 epidemics in Mato Grosso do Sul, Brazil.
Dengue
Dengue nonstructural protein 1 antigen in the urine as a rapid and convenient diagnostic test during the febrile stage in patients with dengue infection.
Dengue
Dengue Nonstructural Protein 1 Maintains Autophagy through Retarding Caspase-Mediated Cleavage of Beclin-1.
Dengue
Dengue NS2A Protein Orchestrates Virus Assembly.
Dengue
Dengue viremia in blood donors in Northern India: Challenges of emerging dengue outbreaks to blood transfusion safety.
Dengue
Dengue virus non-structural protein 1: a pathogenic factor, therapeutic target, and vaccine candidate.
Dengue
Dengue virus nonstructural protein 1 activates platelets via Toll-like receptor 4, leading to thrombocytopenia and hemorrhage.
Dengue
Dengue Virus Nonstructural Protein 1 Induces Vascular Leakage through Macrophage Migration Inhibitory Factor and Autophagy.
Dengue
Dengue virus nonstructural protein 1 is expressed in a glycosyl-phosphatidylinositol-linked form that is capable of signal transduction.
Dengue
Dengue Virus Nonstructural Protein 1-Induced Antibodies Cross-React with Human Plasminogen and Enhance Its Activation.
Dengue
Dengue Virus Nonstructural Protein 5 (NS5) Assembles into a Dimer with a Unique Methyltransferase and Polymerase Interface.
Dengue
Dengue Virus Nonstructural Protein 5 Adopts Multiple Conformations in Solution.
Dengue
Dengue virus nonstructural protein NS1 binds to prothrombin/thrombin and inhibits prothrombin activation.
Dengue
Dengue virus nonstructural protein NS5 induces interleukin-8 transcription and secretion.
Dengue
Dengue virus NS1 protein activates cells via Toll-like receptor 4 and disrupts endothelial cell monolayer integrity.
Dengue
Dengue virus RNA polymerase NS5: a potential therapeutic target?
Dengue
Dengue virus serotyping based on envelope and membrane and nonstructural protein NS1 serotype-specific capture immunoglobulin M enzyme-linked immunosorbent assays.
Dengue
Dengue virus structural differences that correlate with pathogenesis.
Dengue
Detection of dengue virus nonstructural protein 1 (NS1) by using ELISA as a useful laboratory diagnostic method for dengue virus infection of international travelers.
Dengue
Detection of Dengue Virus Nonstructural Protein 1 (NS1) in Urine Samples using ELISA as a Laboratory Diagnostic Method for Dengue Virus Infection.
Dengue
Detection of dengue viruses in field caught male Aedes aegypti and Aedes albopictus (Diptera: Culicidae) in Singapore by type-specific PCR.
Dengue
Determination of viremia and concentration of circulating nonstructural protein 1 in patients infected with dengue virus in Mexico.
Dengue
Development of an antigen capture immunoassay based on monoclonal antibodies specific for dengue virus serotype 2 nonstructural protein 1 for early and rapid identification of dengue virus serotype 2 infections.
Dengue
Development of multiplex real-time reverse transcriptase PCR assays for detecting eight medically important flaviviruses in mosquitoes.
Dengue
Development of robust in vitro RNA-dependent RNA polymerase assay as a possible platform for antiviral drug testing against dengue.
Dengue
Development of single-tube mutiplex RT-PCR for dengue virus typing.
Dengue
Diagnosis of COVID-19 in a Dengue-Endemic Area.
Dengue
Differentially expressed genes of human microvascular endothelial cells in response to anti-dengue virus NS1 antibodies by suppression subtractive hybridization.
Dengue
Discovery of a small molecule inhibitor targeting dengue virus NS5 RNA-dependent RNA polymerase.
Dengue
Discovery of Multitarget Antivirals Acting on Both the Dengue Virus NS5-NS3 Interaction and the Host Src/Fyn Kinases.
Dengue
Discovery of Potent Non-Nucleoside Inhibitors of Dengue Viral RNA-Dependent RNA Polymerase from a Fragment Hit Using Structure-Based Drug Design.
Dengue
Discovery of Potent Non-nucleoside Inhibitors of Dengue Viral RNA-Dependent RNA Polymerase from Fragment Screening and Structure-Guided Design.
Dengue
DNA priming E and NS1 constructs--homologous proteins boosting immunization strategy to improve immune response against dengue in mice.
Dengue
DNA Switch: Toehold-Mediated DNA Isothermal Amplification for Dengue Serotyping.
Dengue
DNA-Modified Plasmonic Sensor for the Direct Detection of Virus Biomarkers from the Blood.
Dengue
Domestic dengue infection with hemophagocytic lymphohistiocytosis successfully treated by early steroid therapy.
Dengue
Dynamic Nucleolar Targeting of Dengue Virus Polymerase NS5 in Response to Extracellular pH.
Dengue
Early dengue diagnosis by nonstructural protein 1 antigen detection: rapid immunochromotography versus two the enzyme-linked immunosorbent assay kits.
Dengue
Effects of Short-Course Oral Corticosteroid Therapy in Early Dengue Infection in Vietnamese Patients: A Randomized, Placebo-Controlled Trial.
Dengue
Electrical detection of dengue biomarker using egg yolk immunoglobulin as the biological recognition element.
Dengue
Elevated dengue virus nonstructural protein 1 serum levels and altered toll-like receptor 4 expression, nitric oxide, and tumor necrosis factor alpha production in dengue hemorrhagic Fever patients.
Dengue
Endothelial cell apoptosis induced by antibodies against dengue virus nonstructural protein 1 via production of nitric oxide.
Dengue
Endothelial Cell Sensitization by Death Receptor Fractions of an Anti-Dengue Nonstructural Protein 1 Antibody Induced Plasma Leakage, Coagulopathy, and Mortality in Mice.
Dengue
Engineered NS1 for Sensitive, Specific Zika Virus Diagnosis from Patient Serology.
Dengue
Enzyme-linked immunosorbent assay specific to Dengue virus type 1 nonstructural protein NS1 reveals circulation of the antigen in the blood during the acute phase of disease in patients experiencing primary or secondary infections.
Dengue
Enzyme-linked immunosorbent assay-format tissue culture infectious dose-50 test for titrating dengue virus.
Dengue
Epitope Sequences in Dengue Virus NS1 Protein Identified by Monoclonal Antibodies.
Dengue
Establishment and characterization of dengue virus type 2 nonstructural protein 1 specific T cell lines.
Dengue
Evaluation of a commercial SD dengue virus NS1 antigen capture enzyme-linked immunosorbent assay kit for early diagnosis of dengue virus infection.
Dengue
Evaluation of cardiac involvement during dengue viral infection.
Dengue
Evaluation of dengue nonstructural protein 1 antigen strip for the rapid diagnosis of patients with dengue infection.
Dengue
Evaluation of protective efficacy using a nonstructural protein NS1 in DNA vaccine-loaded microspheres against dengue 2 virus.
Dengue
Evaluation of rapid diagnostic tests to detect dengue virus infections in Taiwan.
Dengue
Evaluation of sofosbuvir activity and resistance profile against West Nile virus in vitro.
Dengue
Evaluation of the diagnostic accuracy of nonstructural protein 1 Ag-based tests for dengue virus in Asian population: a meta-analysis.
Dengue
Expression and purification of dengue virus NS5 polymerase and development of a high-throughput enzymatic assay for screening inhibitors of dengue polymerase.
Dengue
Expression of cytokine, chemokine, and adhesion molecules during endothelial cell activation induced by antibodies against dengue virus nonstructural protein 1.
Dengue
Expression of dengue virus structural proteins and nonstructural protein NS1 by a recombinant vaccinia virus.
Dengue
Expression of the dengue virus type 2 NS5 protein in a CD4(+) T cell line inhibits HIV replication.
Dengue
Expression, purification, and initial structural characterization of nonstructural protein 2B, an integral membrane protein of Dengue 2, in detergent micelles.
Dengue
F1 Motif of Dengue Virus Polymerase NS5 Is Involved in Promoter-Dependent RNA Synthesis.
Dengue
Facilitation of cell adhesion by immobilized dengue viral nonstructural protein 1 (NS1): arginine-glycine-aspartic acid structural mimicry within the dengue viral NS1 antigen.
Dengue
Fatal Intracranial Hemorrhage in a Patient with Severe Dengue Fever.
Dengue
Finding new medicines for flaviviral targets.
Dengue
Flacourtosides A-F, phenolic glycosides isolated from Flacourtia ramontchi.
Dengue
Flavivirus Cross-Reactivity to Dengue Nonstructural Protein 1 Antigen Detection Assays.
Dengue
Flavivirus induces and antagonizes antiviral RNA interference in both mammals and mosquitoes.
Dengue
Flavivirus NS1 Triggers Tissue-Specific Vascular Endothelial Dysfunction Reflecting Disease Tropism.
Dengue
Full-length dengue virus RNA-dependent RNA polymerase - RNA/DNA complexes. Stoichiometries, intrinsic affinities, cooperativities, base, and conformational specificities.
Dengue
Functional analysis of two cavities in flavivirus NS5 polymerase.
Dengue
Functionalized 2,1-benzothiazine 2,2-dioxides as new inhibitors of Dengue NS5 RNA-dependent RNA polymerase.
Dengue
Generation and characterization of a rat monoclonal antibody against the RNA polymerase protein from Dengue Virus-2.
Dengue
GeneSV - an Approach to Help Characterize Possible Variations in Genomic and Protein Sequences.
Dengue
Glutathionylation of dengue and Zika NS5 proteins affects guanylyltransferase and RNA dependent RNA polymerase activities.
Dengue
Hepatitis C virus shares amino acid sequence similarity with pestiviruses and flaviviruses as well as members of two plant virus supergroups.
Dengue
High circulating levels of the dengue virus nonstructural protein NS1 early in dengue illness correlate with the development of dengue hemorrhagic fever.
Dengue
High levels of serum hyaluronan is an early predictor of dengue warning signs and perturbs vascular integrity.
Dengue
High-Level Expression of Functionally Active Dengue-2 Non-Structural Antigen 1 Production in Escherichia coli.
Dengue
Highly conserved region 141?168 of the NS1 protein is a new common epitope region of dengue virus.
Dengue
Host-Specific NS5 Ubiquitination Determines Yellow Fever Virus Tropism.
Dengue
Human glucose-regulated protein 78 modulates intracellular production and secretion of nonstructural protein 1 of dengue virus.
Dengue
Identification and molecular characterization of human antibody fragments specific for dengue NS5 protein.
Dengue
Identification of a Broad-Spectrum Viral Inhibitor Targeting a Novel Allosteric Site in the RNA-Dependent RNA Polymerases of Dengue Virus and Norovirus.
Dengue
Identification of a Conserved RNA-dependent RNA Polymerase (RdRp)-RNA Interface Required for Flaviviral Replication.
Dengue
Identification of a Pyridoxine-Derived Small-Molecule Inhibitor Targeting Dengue Virus RNA-Dependent RNA Polymerase.
Dengue
Identification of Dengue Viral RNA Dependent RNA Polymerase Inhibitor using Computational Fragment Based Approaches and Molecular Dynamics Study.
Dengue
Identification of human hnRNP C1/C2 as a dengue virus NS1-interacting protein.
Dengue
Identification of the critical linker residues conferring differences in the compactness of NS5 from Dengue virus serotype 4 and NS5 from Dengue virus serotypes 1-3.
Dengue
Identifying initiation and elongation inhibitors of dengue virus RNA polymerase in a high-throughput lead-finding campaign.
Dengue
Immunization of mice with dengue structural proteins and nonstructural protein NS1 expressed by baculovirus recombinant induces resistance to dengue virus encephalitis.
Dengue
Immunization of mice with recombinant vaccinia virus expressing authentic dengue virus nonstructural protein NS1 protects against lethal dengue virus encephalitis.
Dengue
Immunoassay targeting nonstructural protein 5 to differentiate West Nile virus infection from dengue and St. Louis encephalitis virus infections and from flavivirus vaccination.
Dengue
Immunofluorescence-based biosensor for the determination of dengue virus NS1 in clinical samples.
Dengue
Impact of Dengue Vaccination on Serological Diagnosis: Insights From Phase III Dengue Vaccine Efficacy Trials.
Dengue
Improved Immunoassay Sensitivity in Serum as a Result of Polymer-Entrapped Quantum Dots: 'Papaya Particles'.
Dengue
Improving dengue viral antigens detection in dengue patient serum specimens using a low pH glycine buffer treatment.
Dengue
In vitro RNA synthesis from exogenous dengue viral RNA templates requires long range interactions between 5'- and 3'-terminal regions that influence RNA structure.
Dengue
Infant Dengue a 10-Year Experience from a Tertiary Center in South India.
Dengue
Inferring Protective CD8+ T-Cell Epitopes for NS5 Protein of Four Serotypes of Dengue Virus Chinese Isolates Based on HLA-A, -B and -C Allelic Distribution: Implications for Epitope-Based Universal Vaccine Design.
Dengue
Inhibition of alpha/beta interferon signaling by the NS4B protein of flaviviruses.
Dengue
Inhibition of dengue virus replication by novel inhibitors of RNA-dependent RNA polymerase and protease activities.
Dengue
Insights on Dengue and Zika NS5 RNA-dependent RNA polymerase (RdRp) inhibitors.
Dengue
Interaction of dengue virus nonstructural protein 5 with Daxx modulates RANTES production.
Dengue
Interference of dengue replication by blocking the access of 3' SL RNA to the viral RNA-dependent RNA polymerase.
Dengue
Intradermal Delivery of Dendritic Cell-Targeting Chimeric mAbs Genetically Fused to Type 2 Dengue Virus Nonstructural Protein 1.
Dengue
Investigating Dengue Virus Nonstructural Protein 5 (NS5) Nuclear Import.
Dengue
In vitro antiviral activities of extracts derived from Daucus maritimus seeds.
Dengue
Ivermectin Accelerates Circulating Nonstructural Protein 1 (NS1) Clearance in Adult Dengue Patients: A Combined Phase 2/3 Randomized Double-blinded Placebo Controlled Trial.
Dengue
Ivermectin is a specific inhibitor of importin ?/?-mediated nuclear import able to inhibit replication of HIV-1 and dengue virus.
Dengue
Kinetics of plasma viremia and soluble nonstructural protein 1 concentrations in dengue: differential effects according to serotype and immune status.
Dengue
Laboratory diagnostics of dengue fever: An emphasis on the role of commercial dengue virus nonstructural protein 1 antigen rapid test.
Dengue
Liver injury caused by antibodies against dengue virus nonstructural protein 1 in a murine model.
Dengue
Looking for inhibitors of the dengue virus NS5 RNA-dependent RNA-polymerase using a molecular docking approach.
Dengue
Macrophage migration inhibitory factor is critical for dengue NS1-induced endothelial glycocalyx degradation and hyperpermeability.
Dengue
Mass spectrometric analysis of host cell proteins interacting with dengue virus nonstructural protein 1 in dengue virus-infected HepG2 cells.
Dengue
Maternal and Neonatal Outcomes during Dengue Infection Outbreak at a Tertiary National Hospital in Endemic Area of Indonesia.
Dengue
Membrane undulation induced by NS4A of Dengue virus: a molecular dynamics simulation study.
Dengue
Mice immunized with recombinant vaccinia virus expressing dengue 4 virus structural proteins with or without nonstructural protein NS1 are protected against fatal dengue virus encephalitis.
Dengue
Modification of S-Adenosyl-l-Homocysteine as Inhibitor of Nonstructural Protein 5 Methyltransferase Dengue Virus Through Molecular Docking and Molecular Dynamics Simulation.
Dengue
Modulation of the nucleoside triphosphatase/RNA helicase and 5'-RNA triphosphatase activities of Dengue virus type 2 nonstructural protein 3 (NS3) by interaction with NS5, the RNA-dependent RNA polymerase.
Dengue
Molecular basis for specific viral RNA recognition and 2'-O-ribose methylation by the dengue virus nonstructural protein 5 (NS5).
Dengue
Molecular epidemiology of dengue virus serotype 2 in the taiwan 2002 outbreak with envelope gene and nonstructural protein 1 gene analysis.
Dengue
Molecular Investigation of Dengue virus serotype 2 Circulation in Kassala State, Sudan.
Dengue
Molecular mimicry of human endothelial cell antigen by autoantibodies to nonstructural protein 1 of dengue virus.
Dengue
Mosquito protein kinase G phosphorylates flavivirus NS5 and alters flight behavior in aedes aegypti and anopheles gambiae.
Dengue
Mutagenesis of the Dengue virus type 2 NS3 protein within and outside helicase motifs: effects on enzyme activity and virus replication.
Dengue
N-sulfonylanthranilic acid derivatives as allosteric inhibitors of dengue viral RNA-dependent RNA polymerase.
Dengue
Nanodelivery system enhances the immunogenicity of dengue-2 nonstructural protein 1, DENV-2 NS1.
Dengue
Non-nucleoside Inhibitors of Zika Virus RNA-Dependent RNA Polymerase.
Dengue
Nonstructural protein 1 antibody-based epitope-blocking enzyme-linked immunosorbent assay to differentiate Japanese encephalitis virus from dengue virus infections in humans.
Dengue
Nonstructural protein NS1 immunodominant epitope detected specifically in dengue virus infected material by a SELDI-TOF/MS based assay.
Dengue
Nonstructural protein NS1: giving a new structure to dengue diagnosis.
Dengue
Novel 2-phenyl-5-[(E)-2-(thiophen-2-yl)ethenyl]-1,3,4-oxadiazole and 3-phenyl-5-[(E)-2-(thiophen-2-yl)ethenyl]-1,2,4-oxadiazole derivatives as dengue virus inhibitors targeting NS5 polymerase.
Dengue
NS5 from Dengue Virus Serotype 2 Can Adopt a Conformation Analogous to That of Its Zika Virus and Japanese Encephalitis Virus Homologues.
Dengue
Nuclear localization of dengue virus nonstructural protein 5 does not strictly correlate with efficient viral RNA replication and inhibition of type I interferon signaling.
Dengue
Nuclear localization of dengue virus nonstructural protein 5 through its importin alpha/beta-recognized nuclear localization sequences is integral to viral infection.
Dengue
Nuclear localization of flavivirus RNA synthesis in infected cells.
Dengue
Nucleotide sequence and deduced amino acid sequence of the nonstructural proteins of dengue type 3 virus, Bangkok genotype.
Dengue
Nucleotide sequences of the nonstructural protein NS1 gene of three dengue-2 viruses, M1, M2 and M3, isolated in Malaysia from patients with dengue haemorrhagic fever, dengue shock syndrome and dengue fever, respectively.
Dengue
Oriented Immobilization of Single-Domain Antibodies Using SpyTag/SpyCatcher Yields Improved Limits of Detection.
Dengue
Outbreak of Dengue Virus Type 2 - American Samoa, November 2016-October 2018.
Dengue
Partial nucleotide sequencing and molecular evolution of epidemic causing Dengue 2 strains.
Dengue
Peptides targeting dengue viral nonstructural protein 1 inhibit dengue virus production.
Dengue
Phylogenetically based establishment of a dengue virus panel, representing all available genotypes, as a tool in dengue drug discovery.
Dengue
Platelet activation and aggregation response to dengue virus nonstructural protein 1 and domains.
Dengue
Point-of-Use Nanobiosensor for Detection of Dengue Virus NS1 Antigen in Adult Aedes aegypti: A Potential Tool for Improved Dengue Surveillance.
Dengue
Potent Allosteric Dengue Virus NS5 Polymerase Inhibitors: Mechanism of Action and Resistance Profiling.
Dengue
Potential application of nonstructural protein NS1 serotype-specific immunoglobulin G enzyme-linked immunosorbent assay in the seroepidemiologic study of dengue virus infection: correlation of results with those of the plaque reduction neutralization test.
Dengue
Potential Phosphorylation of Viral Nonstructural Protein 1 in Dengue Virus Infection.
Dengue
Prevalence of Dengue Fever in Western Uttar Pradesh, India: A Gender-Based Study.
Dengue
Production and characterization of monospecific and bispecific antibodies against dengue virus NS1 protein.
Dengue
Production of a recombinant Dengue virus 2 NS5 protein and the potential use as a vaccine antigen.
Dengue
Proper processing of dengue virus nonstructural glycoprotein NS1 requires the N-terminal hydrophobic signal sequence and the downstream nonstructural protein NS2a.
Dengue
Proposing drug fragments for dengue virus NS5 protein.
Dengue
Protection against Dengue Virus Infection in Mice by Administration of Antibodies against Modified Nonstructural Protein 1.
Dengue
Quercetin derivatives as non-nucleoside inhibitors for dengue polymerase: molecular docking, molecular dynamics simulation and binding free energy calculation.
Dengue
Re-evaluation of the pathogenic roles of nonstructural protein 1 and its antibodies during dengue virus infection.
Dengue
Recombinant dengue type 1 virus NS5 protein expressed in Escherichia coli exhibits RNA-dependent RNA polymerase activity.
Dengue
Recombinant dengue virus type 1 NS3 protein exhibits specific viral RNA binding and NTPase activity regulated by the NS5 protein.
Dengue
Reduced Featured k-NN Classifier Model Optimal for Classification of Dengue Fever from Salivary Raman Spectra.
Dengue
Relationship between nonstructural protein 1 detection and plasma virus load in Dengue patients.
Dengue
Relative contribution of nonstructural protein 1 in dengue pathogenesis.
Dengue
Repositioning of RdRp Inhibitors against HCV NS5B Polymerase Utilizing Structure-Based Molecular Docking.
Dengue
Repurposing Old Antibodies for New Diseases by Exploiting Cross-Reactivity and Multicolored Nanoparticles.
Dengue
Rhabdomyolysis and dengue Fever: a case report and literature review.
Dengue
RNA sequences and structures required for the recruitment and activity of the dengue virus polymerase.
Dengue
Secreted complement regulatory protein clusterin interacts with dengue virus nonstructural protein 1.
Dengue
Secreted dengue virus nonstructural protein NS1 is an atypical barrel-shaped high-density lipoprotein.
Dengue
Secretion of Nonstructural Protein 1 of Dengue Virus from Infected Mosquito Cells: Facts and Speculations.
Dengue
Serologic diagnosis of West Nile virus infection.
Dengue
Serological evaluation of suspected West Nile virus human cases following its introduction during a dengue outbreak in Puerto Rico in 2007.
Dengue
Serological evidence of leptospirosis in patients with a clinical suspicion of dengue in the State of Ceará, Brazil.
Dengue
Serotype 1-specific monoclonal antibody-based antigen capture immunoassay for detection of circulating nonstructural protein NS1: Implications for early diagnosis and serotyping of dengue virus infections.
Dengue
Serotype-Specific Anti-Dengue Virus NS1 Mouse Antibodies Cross-React with prM and Are Potentially Involved in Virus Production.
Dengue
Serotype-specific detection of dengue viruses in a nonstructural protein 1-based enzyme-linked immunosorbent assay validated with a multi-national cohort.
Dengue
Severe nonfebrile dengue infection in an adolescent after postoperative kidney transplantation: a case report.
Dengue
Sophoraflavenone G Restricts Dengue and Zika Virus Infection via RNA Polymerase Interference.
Dengue
Space constrained homology modelling: the paradigm of the RNA-dependent RNA polymerase of dengue (type II) virus.
Dengue
Specificity of NS1-based immunochromatographic tests for dengue virus with regard to the Zika virus protein.
Dengue
Stabilization of dengue virus polymerase in de novo initiation assay provides advantages for compound screening.
Dengue
Strategies for the treatment of dengue virus infections: a narrative account.
Dengue
Structure and function of the non-structural protein of dengue virus and its applications in antiviral therapy.
Dengue
Structure-activity relationship of uridine-based nucleoside phosphoramidate prodrugs for inhibition of dengue virus RNA-dependent RNA polymerase.
Dengue
Structure-Activity Relationship Study of Biflavonoids on the Dengue Virus Polymerase DENV-NS5 RdRp.
Dengue
Study of the Langat virus RNA-dependent RNA polymerase through homology modeling.
Dengue
Study on the Behavior of Dengue Viruses during Outbreaks with Reference to Entomological and Laboratory Surveillance in the Cuddalore, Nagapattinam, and Tirunelveli Districts of Tamil Nadu, India.
Dengue
Substrate selectivity of Dengue and Zika virus NS5 polymerase towards 2'-modified nucleotide analogues.
Dengue
SUMO Modification Stabilizes Dengue Virus Nonstructural Protein 5.
Dengue
Suppressed humoral immunity is associated with dengue nonstructural protein NS1-elicited anti-death receptor antibody fractions in mice.
Dengue
Surface-Enhanced Raman Spectroscopy-Based Sandwich Immunoassays for Multiplexed Detection of Zika and Dengue Viral Biomarkers.
Dengue
Synthesis of dengue virus RNA in vitro: initiation and the involvement of proteins NS3 and NS5.
Dengue
Targeting flavivirus RNA dependent RNA polymerase through a pyridobenzothiazole inhibitor.
Dengue
Temperature and the field stability of a dengue rapid diagnostic test in the tropics.
Dengue
Temperature requirements for initiation of RNA-dependent RNA polymerization.
Dengue
The 37-amino-acid interdomain of dengue virus NS5 protein contains a functional NLS and inhibitory CK2 site.
Dengue
The C-terminal 50 Amino Acid Residues of Dengue NS3 Protein Are Important for NS3-NS5 Interaction and Viral Replication.
Dengue
The Clinical and Serological Profile of Pediatric Dengue.
Dengue
The dengue virus nonstructural protein 1 (NS1) increases NF-?B transcriptional activity in HepG2 cells.
Dengue
The Dengue Virus Nonstructural Protein 1 (NS1) Is Secreted from Mosquito Cells in Association with the Intracellular Cholesterol Transporter Chaperone Caveolin Complex.
Dengue
The dengue virus NS5 protein as a target for drug discovery.
Dengue
The Dengue Virus NS5 Protein Intrudes in the Cellular Spliceosome and Modulates Splicing.
Dengue
The effect of freeze-dried Carica papaya leaf juice treatment on NS1 and viremia levels in dengue fever mice model.
Dengue
The Good, the Bad, and the Shocking: The Multiple Roles of Dengue Virus Nonstructural Protein 1 in Protection and Pathogenesis.
Dengue
The interdomain region of dengue NS5 protein that binds to the viral helicase NS3 contains independently functional importin beta 1 and importin alpha/beta-recognized nuclear localization signals.
Dengue
The methyltransferase domain of dengue virus protein NS5 ensures efficient RNA synthesis initiation and elongation by the polymerase domain.
Dengue
The nucleotide sequence of dengue type 4 virus: analysis of genes coding for nonstructural proteins.
Dengue
The Role of NS5 Protein in Determination of Host Cell Range for Yellow Fever Virus.
Dengue
The secreted form of dengue virus nonstructural protein NS1 is endocytosed by hepatocytes and accumulates in late endosomes: implications for viral infectivity.
Dengue
The use of dengue nonstructural protein 1 antigen for the early diagnosis during the febrile stage in patients with dengue infection.
Dengue
Tropism of dengue virus in mice and humans defined by viral nonstructural protein 3-specific immunostaining.
Dengue
Two RNA tunnel inhibitors bind in highly conserved sites in Dengue virus NS5 polymerase: structural and functional studies.
Dengue
Use of a Rapid Test for Diagnosis of Dengue during Suspected Dengue Outbreaks in Resource-Limited Regions.
Dengue
Use of a Recombinant Gamma-2 Herpesvirus Vaccine Vector against Dengue Virus in Rhesus Monkeys.
Dengue
Use of dengue nonstructural protein 1 antigen for the early diagnosis of dengue infection.
Dengue
Use of Urea Wash ELISA to Distinguish Zika and Dengue Virus Infections.
Dengue
Using bioinformatics tools for the discovery of Dengue RNA-dependent RNA polymerase inhibitors.
Dengue
Vesicular Stomatitis Virus and DNA Vaccines Expressing Zika Virus Nonstructural Protein 1 Induce Substantial but Not Sterilizing Protection against Zika Virus Infection.
Dengue
Vimentin interacts with heterogeneous nuclear ribonucleoproteins and dengue nonstructural protein 1 and is important for viral replication and release.
Dengue
Zika and Dengue Interactions in the Context of a Large Dengue Vaccine Clinical Trial in Latin America.
Dengue
Zika Virus Disease Comparing Children and Adults in a Dengue-Endemic Setting.
Dengue
Zika virus NS5 localizes at centrosomes during cell division.
Dengue
[Comparison of Dengue viral nonstructural protein 1 antigen testing kits].
Dengue
[To evaluate the neutralizing abilities of anti-dengue virus antibodies with nonstructural protein 1 antigen capture enzyme-linked immunosorbent assay]
Dermatitis, Phototoxic
A General Mechanism of Photoconversion of Green-to-Red Fluorescent Proteins Based on Blue and Infrared Light Reduces Phototoxicity in Live-Cell Single-Molecule Imaging.
Dermatomyositis
Clinicopathological analysis of mechanic's hand associated with dermatomyositis.
Dermatomyositis
The long-term outcome of interstitial lung disease with anti-aminoacyl-tRNA synthetase antibodies.
Dermatomyositis
[Autoantibodies of Inflammatory Myopathies: Update].
Desmoplastic Small Round Cell Tumor
A renal cell carcinoma with EWSR1-TFE3 fusion gene.
Diabetes Mellitus, Type 1
Involvement of the RNA-binding protein ARE/poly(U)-binding factor 1 (AUF1) in the cytotoxic effects of proinflammatory cytokines on pancreatic beta cells.
Diabetes Mellitus, Type 1
T-cell responses to enterovirus antigens in children with type 1 diabetes.
Diabetic Nephropathies
Identification of NOD2 as a novel target of RNA-binding protein HuR: evidence from NADPH oxidase-mediated HuR signaling in diabetic nephropathy.
Diabetic Nephropathies
Interplay between RNA-binding protein HuR and Nox4 as a novel therapeutic target in diabetic kidney disease.
DiGeorge Syndrome
'Black sheep' that don't leave the double-stranded RNA-binding domain fold.
DiGeorge Syndrome
A Collection of Pre-mRNA Splicing Mutants in Arabidopsis thaliana.
DiGeorge Syndrome
Integrative Analysis of NSCLC Identifies LINC01234 as an Oncogenic lncRNA that Interacts with HNRNPA2B1 and Regulates miR-106b Biogenesis.
DiGeorge Syndrome
N6-methyladenosine-dependent primary microRNA-126 processing activated PI3K-AKT-mTOR pathway drove the development of pulmonary fibrosis induced by nanoscale carbon black particles in rats.
DiGeorge Syndrome
The Core Microprocessor Component DiGeorge Syndrome Critical Region 8 (DGCR8) Is a Nonspecific RNA-binding Protein.
Diphtheria
Development, validation and implementation of a quadruplex real-time PCR assay for identification of potentially toxigenic corynebacteria.
Distal Myopathies
Welander distal myopathy is caused by a mutation in the RNA-binding protein TIA1.
Distemper
Canine distemper terminal and intergenic non-protein coding nucleotide sequences: completion of the entire CDV genome sequence.
Distemper
Detection and Preliminary Characterization of Phocine Distemper Virus in a Stranded Harp Seal (Pagophilus groenlandicus) from the Gulf of St. Lawrence, Canada.
Distemper
Development of a challenge-protective vaccine concept by modification of the viral RNA-dependent RNA polymerase of canine distemper virus.
Distemper
Humoral immune response in dogs with old dog encephalitis and chromic distemper meningo-encephalitis.
DNA Virus Infections
Emerging antiviral drugs.
DNA Virus Infections
Highlights in the development of new antiviral agents.
Down Syndrome
Pattern recognition receptors acting in innate immune system of shrimp against pathogen infections.
Dwarfism
Regulation of Rice Tillering by RNA-Directed DNA Methylation at Miniature Inverted-Repeat Transposable Elements.
Dysostoses
tp53-dependent and independent signaling underlies the pathogenesis and possible prevention of Acrofacial Dysostosis - Cincinnati type.
Dyspnea
A randomized and comparative study to assess safety and efficacy of supplemental treatment of a herbal formulation - Aayudh Advance comprising essential oils in patients with corona virus 2019 (COVID-19).
Dystonia
Dystonia in RNA Polymerase III-Related Leukodystrophy.
Dystonia
Novel POLR1C mutation in RNA polymerase III-related leukodystrophy with severe myoclonus and dystonia.
Encephalitis
A novel complex formed between the flavivirus E and NS1 proteins: analysis of its structure and function.
Encephalitis
Antiviral Effects of a Transgenic RNA-Dependent RNA-Polymerase.
Encephalitis
Cold-inducible RNA-binding protein is an important mediator of alcohol-induced brain inflammation.
Encephalitis
Determination of the intramolecular disulfide bond arrangement and biochemical identification of the glycosylation sites of the nonstructural protein NS1 of Murray Valley encephalitis virus.
Encephalitis
Development of multiplex real-time reverse transcriptase PCR assays for detecting eight medically important flaviviruses in mosquitoes.
Encephalitis
Humoral immune response in dogs with old dog encephalitis and chromic distemper meningo-encephalitis.
Encephalitis
Immunization of mice with dengue structural proteins and nonstructural protein NS1 expressed by baculovirus recombinant induces resistance to dengue virus encephalitis.
Encephalitis
Immunization of mice with recombinant vaccinia virus expressing authentic dengue virus nonstructural protein NS1 protects against lethal dengue virus encephalitis.
Encephalitis
Immunoassay targeting nonstructural protein 5 to differentiate West Nile virus infection from dengue and St. Louis encephalitis virus infections and from flavivirus vaccination.
Encephalitis
Impaired T helper 1 function of nonstructural protein 3-specific T cells in Japanese patients with encephalitis with neurological sequelae.
Encephalitis
Mice immunized with recombinant vaccinia virus expressing dengue 4 virus structural proteins with or without nonstructural protein NS1 are protected against fatal dengue virus encephalitis.
Encephalitis
Nonstructural Protein L* Species Specificity Supports a Mouse Origin for Vilyuisk Human Encephalitis Virus.
Encephalitis
Role of amphotericin B upon enhancement of protective immunity elicited by oral administration with liposome-encapsulated-Japanese encephalitis virus nonstructural protein 1 (NS1) in mice.
Encephalitis
[A recombinant adenovirus expressing the NS1 nonstructural protein of tick-borne encephalitis virus: some characteristics of the immunologic basis of antiviral action]
Encephalitis, Arbovirus
Simultaneous detection of three mosquito-borne encephalitis viruses (eastern equine, La Crosse, and St. Louis) with a single-tube multiplex reverse transcriptase polymerase chain reaction assay.
Encephalitis, Japanese
A crystal structure of the Dengue virus NS5 protein reveals a novel inter-domain interface essential for protein flexibility and virus replication.
Encephalitis, Japanese
A structural view of the RNA-dependent RNA polymerases from the Flavivirus genus.
Encephalitis, Japanese
Activation of protein kinase R by hepatitis C virus RNA-dependent RNA polymerase.
Encephalitis, Japanese
Anti-apoptotic activity of Japanese encephalitis virus NS5 protein in human medulloblastoma cells treated with interferon-?.
Encephalitis, Japanese
Antibodies to bovine serum albumin in human sera: problems and solutions with casein-based ELISA in the detection of natural Japanese encephalitis virus infections.
Encephalitis, Japanese
Antibody to the nonstructural protein NS1 of Japanese encephalitis virus: potential application of mAb-based indirect ELISA to differentiate infection from vaccination.
Encephalitis, Japanese
Biochemical characterization of a recombinant Japanese encephalitis virus RNA-dependent RNA polymerase.
Encephalitis, Japanese
Blocking Double-Stranded RNA-Activated Protein Kinase PKR by Japanese Encephalitis Virus Nonstructural Protein 2A.
Encephalitis, Japanese
Characterization of Japanese encephalitis virus envelope protein expressed by recombinant baculoviruses.
Encephalitis, Japanese
Characterization of RNA synthesis, replication mechanism, and in vitro RNA-dependent RNA polymerase activity of Japanese encephalitis virus.
Encephalitis, Japanese
Crystal structure of full-length Zika virus NS5 protein reveals a conformation similar to Japanese encephalitis virus NS5.
Encephalitis, Japanese
DNA immunization with Japanese encephalitis virus nonstructural protein NS1 elicits protective immunity in mice.
Encephalitis, Japanese
Effect of the methyltransferase domain of Japanese encephalitis virus NS5 on the polymerase activity.
Encephalitis, Japanese
Expression and secretion of Japanese encephalitis virus nonstructural protein NS1 by insect cells using a recombinant baculovirus.
Encephalitis, Japanese
Flavivirus Nonstructural Protein NS5 Dysregulates HSP90 to Broadly Inhibit JAK/STAT Signaling.
Encephalitis, Japanese
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) interaction with 3' ends of Japanese encephalitis virus RNA and colocalization with the viral NS5 protein.
Encephalitis, Japanese
Identification and characterization of RNA-dependent RNA polymerase activity in recombinant Japanese encephalitis virus NS5 protein.
Encephalitis, Japanese
Identification of residues critical for the interferon antagonist function of Langat virus NS5 reveals a role for the RNA-dependent RNA polymerase domain.
Encephalitis, Japanese
Immunogenicity of baculovirus expressed recombinant proteins of Japanese encephalitis virus in mice.
Encephalitis, Japanese
In vitro synthesis of Japanese encephalitis virus (JEV) RNA: membrane and nuclear fractions of JEV-infected cells possess high levels of virus-specific RNA polymerase activity.
Encephalitis, Japanese
Inhibition of expression of rna polymerase with small interfering RNAs targeting a conserved motif in the respective viral genes in viruses of the family Flaviviridae.
Encephalitis, Japanese
Japanese encephalitis virus nonstructural protein NS5 interacts with mitochondrial trifunctional protein and impairs fatty acid ?-oxidation.
Encephalitis, Japanese
Japanese Encephalitis Virus NS5 Inhibits Type I Interferon (IFN) Production by Blocking the Nuclear Translocation of IFN Regulatory Factor 3 and NF-?B.
Encephalitis, Japanese
Japanese encephalitis virus structural and nonstructural proteins expressed in Escherichia coli induce protective immunity in mice.
Encephalitis, Japanese
Last twenty amino acids of the West Nile Virus NS1' protein are responsible for its retention in cells and formation of unique heat-stable dimers.
Encephalitis, Japanese
Mechanistic insights into the Japanese encephalitis virus RNA dependent RNA polymerase protein inhibition by bioflavonoids from Azadirachta indica.
Encephalitis, Japanese
Modulatory effects of the human heat shock protein 70 on DNA vaccination.
Encephalitis, Japanese
Nanoparticle-Based LDI-MS Immunoassay for the Multiple Diagnosis of Viral Infections.
Encephalitis, Japanese
Nonstructural protein 1 antibody-based epitope-blocking enzyme-linked immunosorbent assay to differentiate Japanese encephalitis virus from dengue virus infections in humans.
Encephalitis, Japanese
NS5 from Dengue Virus Serotype 2 Can Adopt a Conformation Analogous to That of Its Zika Virus and Japanese Encephalitis Virus Homologues.
Encephalitis, Japanese
Nuclear localization of flavivirus RNA synthesis in infected cells.
Encephalitis, Japanese
Partial nucleotide sequence of Japanese encephalitis virus ling strain genome and comparison of the encoded structural proteins and nonstructural protein NS1 among Japanese encephalitis virus strains.
Encephalitis, Japanese
Persistence of Japanese encephalitis virus is associated with abnormal expression of the nonstructural protein NS1 in host cells.
Encephalitis, Japanese
Preparation of Japanese encephalitis virus nonstructural protein NS1 obtained from culture fluid of JEV-infected Vero cells.
Encephalitis, Japanese
Proteomic analyses identify intracellular targets for Japanese encephalitis virus nonstructural protein 1 (NS1).
Encephalitis, Japanese
Proteomic analysis for Type I interferon antagonism of Japanese encephalitis virus NS5 protein.
Encephalitis, Japanese
Purification and renaturation of Japanese encephalitis virus nonstructural glycoprotein NS1 overproduced by insect cells.
Encephalitis, Japanese
Recognition of nonstructural protein peptides by cytotoxic T lymphocytes raised against Japanese encephalitis virus.
Encephalitis, Japanese
RNA-dependent RNA polymerase of Japanese encephalitis virus binds the initiator nucleotide GTP to form a mechanistically important pre-initiation state.
Encephalitis, Japanese
Structural Study of the C-Terminal Domain of Nonstructural Protein 1 from Japanese Encephalitis Virus.
Encephalitis, Japanese
Structure and function of the Zika virus full-length NS5 protein.
Encephalitis, Japanese
The C Terminus of the Core ?-Ladder Domain in Japanese Encephalitis Virus Nonstructural Protein 1 Is Flexible for Accommodation of Heterologous Epitope Fusion.
Encephalitis, Japanese
Utilization of complement-dependent cytotoxicity to measure low levels of antibodies: application to nonstructural protein 1 in a model of Japanese encephalitis virus.
Encephalitis, Japanese
Virus-specific cytolytic antibodies to nonstructural protein 1 of Japanese encephalitis virus effect reduction of virus output from infected cells.
Encephalitis, Tick-Borne
A database of human genes and a gene network involved in response to tick-borne encephalitis virus infection.
Encephalitis, Tick-Borne
Affinity labelling of the tick-borne encephalitis virus RNA replicase proteins by 4-N-exo-base-substituted photoreactive CTP analogs.
Encephalitis, Tick-Borne
An E460D Substitution in the NS5 Protein of Tick-Borne Encephalitis Virus Confers Resistance to the Inhibitor Galidesivir (BCX4430) and Also Attenuates the Virus for Mice.
Encephalitis, Tick-Borne
An RNA-dependent RNA polymerase inhibitor for tick-borne encephalitis virus.
Encephalitis, Tick-Borne
Assessing ubiquitination of viral proteins: Lessons from flavivirus NS5.
Encephalitis, Tick-Borne
Crystal structure of a tick-borne flavivirus RNA-dependent RNA polymerase suggests a host adaptation hotspot in RNA viruses.
Encephalitis, Tick-Borne
Escape of tick-borne flavivirus from 2' -C-methylated nucleoside antivirals is mediated by a single conservative mutation in NS5 that has a dramatic effect on viral fitness.
Encephalitis, Tick-Borne
Extension of flavivirus protein C differentially affects early RNA synthesis and growth in mammalian and arthropod host cells.
Encephalitis, Tick-Borne
Identification of residues critical for the interferon antagonist function of Langat virus NS5 reveals a role for the RNA-dependent RNA polymerase domain.
Encephalitis, Tick-Borne
Identification of RNA replicase subunits responsible for initiation of RNA synthesis of tick-borne encephalitis virus by affinity labelling.
Encephalitis, Tick-Borne
Nonstructural Protein 1 of Tick-Borne Encephalitis Virus Induces Oxidative Stress and Activates Antioxidant Defense by the Nrf2/ARE Pathway.
Encephalitis, Tick-Borne
Nucleotide sequence of the genome and complete amino acid sequence of the polyprotein of tick-borne encephalitis virus.
Encephalitis, Tick-Borne
Phosphorylation of tick-borne encephalitis virus NS5 protein.
Encephalitis, Tick-Borne
Synthesis of new photocross-linking 5-C-base-substituted UTP analogs and their application in highly selective affinity labelling of the tick-borne encephalitis virus RNA replicase proteins.
Encephalitis, Tick-Borne
Tick-Borne Encephalitis Virus Nonstructural Protein NS5 Induces RANTES Expression Dependent on the RNA-Dependent RNA Polymerase Activity.
Encephalitis, Tick-Borne
Tick-borne encephalitis virus NS5 associates with membrane protein scribble and impairs interferon-stimulated JAK-STAT signalling.
Encephalitis, Tick-Borne
TRIM79?, an interferon-stimulated gene product, restricts tick-borne encephalitis virus replication by degrading the viral RNA polymerase.
Encephalitis, Tick-Borne
[A recombinant adenovirus expressing the NS1 nonstructural protein of tick-borne encephalitis virus: some characteristics of the immunologic basis of antiviral action]
Encephalitis, Tick-Borne
[Humoral immune response to structural and nonstructural proteins of tick-borne encephalitis virus in the natural history of the disease]
Encephalitis, Tick-Borne
[Nonstructural protein 1 of tick-borne encephalitis virus activates the expression of immunoproteasome subunits].
Encephalitis, Tick-Borne
[Nonstructural protein NV5 of the tick-borne encephalitis virus possesses precipitating activity characteristic for the nonvirion (soluble) antigen]
Encephalitis, Tick-Borne
[Protective activity of a bacterial plasmid, bearing the gene for the tick-borne encephalitis virus NS1 nonstructural protein]
Encephalitis, Tick-Borne
[Synthetic fragments of the NS1 protein of the tick-borne encephalitis virus exhibiting a protective effect]
Encephalitis, Viral
Japanese Encephalitis Virus NS5 Inhibits Type I Interferon (IFN) Production by Blocking the Nuclear Translocation of IFN Regulatory Factor 3 and NF-?B.
Encephalitis, Viral
[Molecular Epidemiology of Echovirus 30 in Longyan City, Fujian, China, 2011?2014].
Encephalomyelitis
Antibody to parvovirus B19 nonstructural protein is associated with chronic arthralgia in patients with chronic fatigue syndrome/myalgic encephalomyelitis.
Encephalomyelitis
Avian encephalomyelitis virus nonstructural protein 2C induces apoptosis by activating cytochrome c/caspase-9 pathway.
Encephalomyelitis
Dysfunctional RNA-binding protein biology and neurodegeneration in experimental autoimmune encephalomyelitis in female mice.
Encephalomyelitis
Molecular analysis of three Ljungan virus isolates reveals a new, close-to-root lineage of the Picornaviridae with a cluster of two unrelated 2A proteins.
Encephalomyelitis
Posttranscriptional gene regulation of IL-17 by the RNA-binding protein HuR is required for initiation of experimental autoimmune encephalomyelitis.
Encephalomyelitis
Silencing of the RNA-binding protein HuR attenuates hyperalgesia and motor disability in experimental autoimmune encephalomyelitis.
Encephalomyelitis
Targeting the RNA-Binding Protein HuR Alleviates Neuroinflammation in Experimental Autoimmune Encephalomyelitis: Potential Therapy for Multiple Sclerosis.
Encephalomyelitis
TDP-43 proteinopathy in Theiler's murine encephalomyelitis virus infection.
Encephalomyelitis
The 2A proteins of three diverse picornaviruses are related to each other and to the H-rev107 family of proteins involved in the control of cell proliferation.
Encephalomyelitis
The cleavage activities of aphthovirus and cardiovirus 2A proteins.
Encephalomyelitis
The Theiler's murine encephalomyelitis virus leader protein is the only nonstructural protein tested that induces apoptosis when transfected into mammalian cells.
Encephalomyelitis
The VP1 protein of avian encephalomyelitis virus is a major host-protective immunogen that serves as diagnostic potential.
Encephalomyelitis
Theiler's murine encephalomyelitis virus 3D RNA polymerase: its expression in the CNS and the specific immune response generated in persistently infected mice.
Encephalomyelitis, Autoimmune, Experimental
Dysfunctional RNA-binding protein biology and neurodegeneration in experimental autoimmune encephalomyelitis in female mice.
Encephalomyelitis, Autoimmune, Experimental
Posttranscriptional gene regulation of IL-17 by the RNA-binding protein HuR is required for initiation of experimental autoimmune encephalomyelitis.
Encephalomyelitis, Autoimmune, Experimental
Silencing of the RNA-binding protein HuR attenuates hyperalgesia and motor disability in experimental autoimmune encephalomyelitis.
Encephalomyelitis, Autoimmune, Experimental
Targeting the RNA-Binding Protein HuR Alleviates Neuroinflammation in Experimental Autoimmune Encephalomyelitis: Potential Therapy for Multiple Sclerosis.
Encephalomyelitis, Eastern Equine
A comparison of the nucleotide sequences of eastern and western equine encephalomyelitis viruses with those of other alphaviruses and related RNA viruses.
Encephalomyelitis, Eastern Equine
Structural and nonstructural protein genome regions of eastern equine encephalitis virus are determinants of interferon sensitivity and murine virulence.
Encephalomyelitis, Venezuelan Equine
Hypervariable domain of nonstructural protein nsP3 of Venezuelan equine encephalitis virus determines cell-specific mode of virus replication.
Encephalomyelitis, Venezuelan Equine
Low-fidelity Venezuelan equine encephalitis virus polymerase mutants to improve live-attenuated vaccine safety and efficacy.
Encephalomyelitis, Venezuelan Equine
Viral RNA-dependent RNA polymerase mutants display an altered mutation spectrum resulting in attenuation in both mosquito and vertebrate hosts.
Encephalomyelitis, Venezuelan Equine
[Activity and properties of RNA-dependent RNA polymerase induced in cell cultures infected with Venezuelan equine encephalomyelitis virus]
Encephalomyelitis, Western Equine
A comparison of the nucleotide sequences of eastern and western equine encephalomyelitis viruses with those of other alphaviruses and related RNA viruses.
Encephalomyelitis, Western Equine
Reverse transcription-PCR-enzyme-linked immunosorbent assay for rapid detection and differentiation of alphavirus infections.
Encephalomyelitis, Western Equine
[Similarities and differences between western equine encephalomyelitis viruses with respect to genes for nonstructural protein NSP2 and structural proteins C and E2]
Endocarditis
Culture-negative endocarditis due to Bartonella quintana.
Endodermal Sinus Tumor
RNA-binding protein LIN28 is a sensitive marker of pediatric yolk sac tumors.
Endometrial Hyperplasia
Expression of cold-inducible RNA-binding protein in the normal endometrium, endometrial hyperplasia, and endometrial carcinoma.
Endometrial Neoplasms
Expression of cold-inducible RNA-binding protein in the normal endometrium, endometrial hyperplasia, and endometrial carcinoma.
Endometrial Neoplasms
[Antisense oligodeoxynucleotides of human telomerase reverse transcriptase inhibit endometrial carcinoma cell HEC-1A proliferation]
Endotoxemia
Toll-like receptor 4 mediates synergism between alcohol and HCV in hepatic oncogenesis involving stem cell marker Nanog.
Enteritis
Calicivirus infection in pediatric small intestine transplant recipients: pathological considerations.
Enteritis
Evidence for recombination in neboviruses.
Enteritis
Mink Enteritis Virus Infection Induces Mitochondrion-mediated Apoptosis by the Viral Nonstructural Protein 1.
Enterocolitis
Incidence of and factors associated with false positives in laboratory diagnosis of norovirus infection by amplification of the RNA-dependent RNA polymerase gene.
Enterovirus Infections
Acute enterovirus infection followed by myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and viral persistence.
Enzootic Bovine Leukosis
Bovine leukemia virus: an exogenous RNA oncogenic virus.
Enzootic Bovine Leukosis
Bovine leukemia virus: an exogenous RNA oncogenic virus?
Enzootic Bovine Leukosis
RNA polymerase isolated from bovine lymphosarcoma by sequential low- and high-salt extraction.
Eosinophilia
Interleukin-5 mRNA in three T-cell lymphomas with eosinophilia.
Ependymoma
TERTp Mutation Detection in Plasma by Droplet-Digital Polymerase Chain Reaction in Spinal Myxopapillary Ependymoma with Lung Metastases.
Ephemeral Fever
Finding potential inhibitors against RNA-dependent RNA polymerase (RdRp) of bovine ephemeral fever virus (BEFV): an in-silico study.
Ephemeral Fever
RNA polymerase (L) gene and genome terminal sequences of ephemeroviruses bovine ephemeral fever virus and Adelaide River virus indicate a close relationship to vesiculoviruses.
Epilepsy
Aberrant sodium channel activity in the complex seizure disorder of Celf4 mutant mice.
Epilepsy
CELF4 regulates translation and local abundance of a vast set of mRNAs, including genes associated with regulation of synaptic function.
Epilepsy
Etiology of a genetically complex seizure disorder in Celf4 mutant mice.
Epilepsy
RNA Polymerase 1 Is Transiently Regulated by Seizures and Plays a Role in a Pharmacological Kindling Model of Epilepsy.
Erythema Infectiosum
Antibodies to the nonstructural protein of parvovirus B19 in persistently infected patients: implications for pathogenesis.
Erythema Infectiosum
[Detection of human parvovirus B19 nonstructural protein DNA by nested- polymerase chain reaction in pregnant women]
Esophageal Neoplasms
Nicotine-Induced ILF2 Facilitates Nuclear mRNA Export of Pluripotency Factors to Promote Stemness and Chemoresistance in Human Esophageal Cancer.
Esophageal Neoplasms
Overexpression of miR-214-3p in esophageal squamous cancer cells enhances sensitivity to cisplatin by targeting survivin directly and indirectly through CUG-BP1.
Esophageal Squamous Cell Carcinoma
Tumor-promoting function and prognostic significance of the RNA-binding protein T-cell intracellular antigen-1 in esophageal squamous cell carcinoma.
Essential Tremor
FUS/TLS deficiency causes behavioral and pathological abnormalities distinct from amyotrophic lateral sclerosis.
Essential Tremor
The role of FUS gene variants in neurodegenerative diseases.
Exanthema
Integrated Diagnosis Project for Inflammatory Myopathies: An association between autoantibodies and muscle pathology.
Exanthema
Skeletal Muscle Involvement in Antisynthetase Syndrome.
Exanthema
[Antisynthetase myopathy].
Fatty Liver
Mice Deficient in the RNA-Binding Protein Zfp871 Are Prone to Early Death and Steatohepatitis in Part through the p53-Mdm2 Axis.
Fatty Liver
SIRT1 mediates the role of RNA-binding protein QKI 5 in the synthesis of triglycerides in non-alcoholic fatty liver disease mice via the PPAR?/FoxO1 signaling pathway.
Feline Panleukopenia
A nonstructural protein of feline panleukopenia virus: expression in Escherichia coli and detection of multiple forms in infected cells.
Fibroadenoma
Immunohistochemical evaluation of reverse transcriptase in breast carcinoma with polyclonal antibodies raised in rabbit.
Fibroadenoma
Molecular cloning and expression of collagenase-3, a novel human matrix metalloproteinase produced by breast carcinomas.
Flavivirus Infections
Comparison of centrifugation methods for molecular and morphological analysis of membranes associated with RNA replication of the flavivirus Kunjin.
Flavivirus Infections
Enzyme-linked immunosorbent assay specific to Dengue virus type 1 nonstructural protein NS1 reveals circulation of the antigen in the blood during the acute phase of disease in patients experiencing primary or secondary infections.
Flavivirus Infections
Highly Sensitive Detection of Zika Virus Nonstructural Protein 1 in Serum Samples by a Two-Site Nanobody ELISA.
Flavivirus Infections
Nuclear localisation of West Nile virus NS5 protein modulates host gene expression.
Flavivirus Infections
Purification and renaturation of Japanese encephalitis virus nonstructural glycoprotein NS1 overproduced by insect cells.
Flavivirus Infections
The C Terminus of the Core ?-Ladder Domain in Japanese Encephalitis Virus Nonstructural Protein 1 Is Flexible for Accommodation of Heterologous Epitope Fusion.
Flavivirus Infections
Vesicular Stomatitis Virus and DNA Vaccines Expressing Zika Virus Nonstructural Protein 1 Induce Substantial but Not Sterilizing Protection against Zika Virus Infection.
Foot-and-Mouth Disease
A cell adhesion peptide from foot-and-mouth disease virus can direct cell targeted delivery of a functional enzyme.
Foot-and-Mouth Disease
A novel bi-functional DNA vaccine expressing VP1 protein and producing antisense RNA targeted to 5'UTR of foot-and-mouth disease virus can induce both rapid inhibitory effect and specific immune response in mice.
Foot-and-Mouth Disease
A peptide construct containing B-cell and T-cell epitopes from the foot-and-mouth disease viral VP1 protein induces efficient antiviral protection.
Foot-and-Mouth Disease
A peptide vaccine administered transcutaneously together with cholera toxin elicits potent neutralising anti-FMDV antibody responses.
Foot-and-Mouth Disease
A recombinant foot-and-mouth disease virus antigen inhibits DNA replication and triggers the SOS response in Escherichia coli.
Foot-and-Mouth Disease
A single amino acid substitution in nonstructural protein 3A can mediate adaptation of foot-and-mouth disease virus to the guinea pig.
Foot-and-Mouth Disease
A T cell epitope in VP1 of foot-and-mouth disease virus is immunodominant for vaccinated cattle.
Foot-and-Mouth Disease
Accuracy of herdsmen reporting versus serologic testing for estimating foot-and-mouth disease prevalence.
Foot-and-Mouth Disease
Activity of foot-and-mouth disease virus RNA-dependent RNA polymerase in vitro: inhibition by polyamines and poly(amino acid)s.
Foot-and-Mouth Disease
An efficient colorimetric assay for RNA synthesis by viral RNA-dependent RNA polymerases, using thermostable pyrophosphatase.
Foot-and-Mouth Disease
An ELISA based on the repeated foot-and-mouth disease virus 3B epitope peptide can distinguish infected and vaccinated cattle.
Foot-and-Mouth Disease
An increased replication fidelity mutant of foot-and-mouth disease virus retains fitness in vitro and virulence in vivo.
Foot-and-Mouth Disease
Antigenicity of a viral peptide displayed on beta-galactosidase fusion proteins is influenced by the presence of the homologous partner protein.
Foot-and-Mouth Disease
Association of foot-and-mouth disease virus induced RNA polymerase with host cell organelles.
Foot-and-Mouth Disease
Attenuation of Foot-and-Mouth Disease Virus by Engineered Viral Polymerase Fidelity.
Foot-and-Mouth Disease
Biosensor characterization of antigenic site A of foot-and-mouth disease virus presented in different vector systems.
Foot-and-Mouth Disease
Both cis and trans Activities of Foot-and-Mouth Disease Virus 3D Polymerase Are Essential for Viral RNA Replication.
Foot-and-Mouth Disease
Bovine serum panel for evaluating foot-and-mouth disease virus nonstructural protein antibody tests.
Foot-and-Mouth Disease
Cellular Vimentin Interacts with Foot-and-Mouth Disease Virus Nonstructural Protein 3A and Negatively Modulates Viral Replication.
Foot-and-Mouth Disease
Characterization of a foot-and-mouth disease mutant temperature-sensitive for viral RNA synthesis.
Foot-and-Mouth Disease
Characterization of a full-length infectious cDNA clone and a green fluorescent protein reporter derivative of the oncolytic picornavirus SVV-001.
Foot-and-Mouth Disease
Chimeric hepatitis B virus core particles as probes for studying peptide-integrin interactions.
Foot-and-Mouth Disease
Coexpression of interleukin-12 chains by a self-splicing vector increases the protective cellular immune response of DNA and Mycobacterium bovis BCG vaccines against Mycobacterium tuberculosis.
Foot-and-Mouth Disease
Comparative Evaluation of Three Commercial ELISA Kits for Detection of Antibodies to a Nonstructural Protein of Foot-and-Mouth Disease Virus.
Foot-and-Mouth Disease
Comparative evaluation of two ELISA kits for detecting antibodies to a nonstructural protein of foot-and-mouth disease virus using serum samples collected from naturally and experimentally infected cows.
Foot-and-Mouth Disease
Comparison of immune responses against foot-and-mouth disease virus induced by fusion proteins using the swine IgG heavy chain constant region or beta-galactosidase as a carrier of immunogenic epitopes.
Foot-and-Mouth Disease
Conformational flexibility in a highly mobile protein loop of foot-and-mouth disease virus: distinct structural requirements for integrin and antibody binding.
Foot-and-Mouth Disease
Construction and characterization of 3A-epitope-tagged foot-and-mouth disease virus.
Foot-and-Mouth Disease
Contribution of a Multifunctional Polymerase Region of Foot-and-Mouth Disease Virus to Lethal Mutagenesis.
Foot-and-Mouth Disease
Converging antigenic structure of a recombinant viral peptide displayed on different frameworks of carrier proteins.
Foot-and-Mouth Disease
Counteracting quasispecies adaptability: extinction of a ribavirin-resistant virus mutant by an alternative mutagenic treatment.
Foot-and-Mouth Disease
Delivery of a foot-and-mouth disease virus empty capsid subunit antigen with nonstructural protein 2B improves protection of swine.
Foot-and-Mouth Disease
Design and construction of African swine fever virus chimeras incorporating foreign viral epitopes.
Foot-and-Mouth Disease
Detection of antibodies specific for foot-and-mouth disease virus infection using indirect ELISA based on recombinant nonstructural protein 2B.
Foot-and-Mouth Disease
Detergent-solubilized RNA polymerase from cells infected with foot-and-mouth disease virus.
Foot-and-Mouth Disease
Determinants of RNA-dependent RNA polymerase (in)fidelity revealed by kinetic analysis of the polymerase encoded by a foot-and-mouth disease virus mutant with reduced sensitivity to ribavirin.
Foot-and-Mouth Disease
Development and evaluation of an indirect enzyme-linked immunosorbent assay for detection of foot-and-mouth disease virus nonstructural protein antibody using a chemically synthesized 2B peptide as antigen.
Foot-and-Mouth Disease
Development of a foot-and-mouth disease NSP ELISA and its comparison with differential diagnostic methods.
Foot-and-Mouth Disease
Development of a recombinant vaccine against foot and mouth disease utilizing mutant attenuated Listeria ivanovii strain as a live vector.
Foot-and-Mouth Disease
Development of synthetic peptide ELISA based on nonstructural protein 2C of foot and mouth disease virus.
Foot-and-Mouth Disease
Diagnostic potential of recombinant nonstructural protein 3B to detect antibodies induced by foot-and-mouth disease virus infection in bovines.
Foot-and-Mouth Disease
Differentiation of foot-and-mouth disease virus-infected from vaccinated pigs by enzyme-linked immunosorbent assay using nonstructural protein 3AB as the antigen and application to an eradication program.
Foot-and-Mouth Disease
Discriminating foot-and-mouth disease virus-infected and vaccinated animals by use of beta-galactosidase allosteric biosensors.
Foot-and-Mouth Disease
Distinct mechanisms of antibody-mediated enzymatic reactivation in beta-galactosidase molecular sensors.
Foot-and-Mouth Disease
eEF1G interaction with foot-and-mouth disease virus nonstructural protein 2B: Identification by yeast two-hybrid system.
Foot-and-Mouth Disease
Effects of temperature on viral RNA synthesis and RNA polymerase activity in a foot-and-mouth disease virus system.
Foot-and-Mouth Disease
Efficient inhibition of foot-and-mouth disease virus replication in vitro by artificial microRNA targeting 3D polymerase.
Foot-and-Mouth Disease
Erratum to: The carboxy-terminal half of nonstructural protein 3A is not essential for foot-and-mouth disease virus replication in cultured cell lines.
Foot-and-Mouth Disease
Evaluation of primers for PCR amplification of RNA polymerase gene sequences of foot-and-mouth disease virus.
Foot-and-Mouth Disease
Evidence of VP1 of duck hepatitis A type 1 virus as a target of neutralizing antibodies and involving receptor-binding activity.
Foot-and-Mouth Disease
Expression and Stability of Foreign Epitopes Introduced into 3A Nonstructural Protein of Foot-and-Mouth Disease Virus.
Foot-and-Mouth Disease
Expression of a foot-and-mouth disease virus immunodominant epitope by a filamentous bacteriophage vector.
Foot-and-Mouth Disease
Expression of an active foot-and-mouth disease virus RNA polymerase in Escherichia coli.
Foot-and-Mouth Disease
Expression of the Foot-and-Mouth Disease Virus VP1 protein using a replication-competent recombinant canine adenovirus type 2 elicits a humoral antibody response in a porcine model.
Foot-and-Mouth Disease
Expression of VP1 protein of serotype A and O of foot-and-mouth disease virus in transgenic sunnhemp plants and its immunogenicity for guinea pigs.
Foot-and-Mouth Disease
Expression, purification, crystallization and preliminary X-ray diffraction analysis of swine leukocyte antigen 2 complexed with a CTL epitope AS64 derived from Asia1 serotype of foot-and-mouth disease virus.
Foot-and-Mouth Disease
Extension of flavivirus protein C differentially affects early RNA synthesis and growth in mammalian and arthropod host cells.
Foot-and-Mouth Disease
Factors required for the Uridylylation of the foot-and-mouth disease virus 3B1, 3B2, and 3B3 peptides by the RNA-dependent RNA polymerase (3Dpol) in vitro.
Foot-and-Mouth Disease
Field outbreak strains of serotype O foot-and-mouth disease virus from India with a deletion in the immunodominant ?G-?H loop of the VP1 protein.
Foot-and-Mouth Disease
Foot-and-mouth disease virus low-fidelity polymerase mutants are attenuated.
Foot-and-Mouth Disease
Foot-and-mouth disease virus nonstructural protein 2B interacts with cyclophilin A, modulating virus replication.
Foot-and-Mouth Disease
Foot-and-mouth disease virus particles contain replicase protein 3D.
Foot-and-Mouth Disease
Foot-and-mouth disease virus type O specific mutations determine RNA-dependent RNA polymerase fidelity and virus attenuation.
Foot-and-Mouth Disease
Foot-and-mouth disease virus VP1 protein fused with cholera toxin B subunit expressed in Chlamydomonas reinhardtii chloroplast.
Foot-and-Mouth Disease
Foot-and-mouth disease virus, but not bovine enterovirus, targets the host cell cytoskeleton via the nonstructural protein 3Cpro.
Foot-and-Mouth Disease
Foot-and-mouth disease virus-induced RNA polymerase is associated with Golgi apparatus.
Foot-and-Mouth Disease
Foot-and-mouth disease virus-infected but not vaccinated cattle develop antibodies against recombinant 3AB1 nonstructural protein.
Foot-and-Mouth Disease
Formation of higher-order foot-and-mouth disease virus 3D(pol) complexes is dependent on elongation activity.
Foot-and-Mouth Disease
Function of the RNA Coliphage Q? Proteins in Medical In Vitro Evolution.
Foot-and-Mouth Disease
Further evaluation of an ELISA kit for detection of antibodies to a nonstructural protein of foot-and-mouth disease virus.
Foot-and-Mouth Disease
High-affinity antibody induced by immunization with a synthetic peptide is associated with protection of cattle against foot-and-mouth disease.
Foot-and-Mouth Disease
Homology Modeling and Analysis of Structure Predictions of the Bovine Rhinitis B Virus RNA Dependent RNA Polymerase (RdRp).
Foot-and-Mouth Disease
Identification of a conformational neutralizing epitope on the VP1 protein of type A foot-and-mouth disease virus.
Foot-and-Mouth Disease
Identification of a conserved linear epitope on the VP1 protein of serotype O foot-and-mouth disease virus by neutralising monoclonal antibody 8E8.
Foot-and-Mouth Disease
Identification of amino acid and nucleotide sequence of the foot-and-mouth disease virus RNA polymerase.
Foot-and-Mouth Disease
Immunogenicity of plasmids encoding T and B cell epitopes of foot-and-mouth disease virus (FMDV) in swine.
Foot-and-Mouth Disease
Improved immunogenicity of a peptide epitope after fusion to hepatitis B core protein.
Foot-and-Mouth Disease
Improving baculovirus transduction of mammalian cells by surface display of a RGD-motif.
Foot-and-Mouth Disease
Increased efficacy of an adenovirus-vectored foot-and-mouth disease capsid subunit vaccine expressing nonstructural protein 2B is associated with a specific T cell response.
Foot-and-Mouth Disease
Indirect ELISA using recombinant nonstructural protein 3D to detect foot and mouth disease virus infection associated antibodies.
Foot-and-Mouth Disease
Induction of a protective response in swine vaccinated with DNA encoding foot-and-mouth disease virus empty capsid proteins and the 3D RNA polymerase.
Foot-and-Mouth Disease
Induction of active immune suppression by co-immunization with DNA- and protein-based vaccines.
Foot-and-Mouth Disease
Influence of hydrophilic amino acids and GC-content on expression of recombinant proteins used in vaccines against foot-and-mouth disease virus in Escherichia coli.
Foot-and-Mouth Disease
Inhibition of the foot-and-mouth disease virus subgenomic replicon by RNA aptamers.
Foot-and-Mouth Disease
Inhibitors of foot and mouth disease virus targeting a novel pocket of the RNA-dependent RNA polymerase.
Foot-and-Mouth Disease
Insertion of a 27 amino acid viral peptide in different zones of Escherichia coli beta-galactosidase: effects on the enzyme activity.
Foot-and-Mouth Disease
Inter-laboratory comparison of 2 ELISA kits used for foot-and-mouth disease virus nonstructural protein serology.
Foot-and-Mouth Disease
Interaction of foot-and-mouth disease virus nonstructural protein 3A with host protein DCTN3 is important for viral virulence in cattle.
Foot-and-Mouth Disease
Intranasal immunization of guinea pigs with an immunodominant foot-and-mouth disease virus peptide conjugate induces mucosal and humoral antibodies and protection against challenge.
Foot-and-Mouth Disease
Isolation of a soluble and template-dependent foot-and-mouth disease virus RNA polymerase.
Foot-and-Mouth Disease
Isolation of novel sequences targeting highly variable viral protein hemagglutinin.
Foot-and-Mouth Disease
Leader protein of foot-and-mouth disease virus is required for cleavage of the p220 component of the cap-binding protein complex.
Foot-and-Mouth Disease
Liposome encapsulated subunit (VP1) and virion vaccines against foot-and-mouth disease.
Foot-and-Mouth Disease
Molecular characterization of a dual inhibitory and mutagenic activity of 5-fluorouridine triphosphate on viral RNA synthesis. Implications for lethal mutagenesis.
Foot-and-Mouth Disease
Molecular characterization of amino acid deletion in VP1 (1D) protein and novel amino acid substitutions in 3D polymerase protein of foot and mouth disease virus subtype A/Iran87.
Foot-and-Mouth Disease
Monoclonal antibodies against foot-and-mouth disease virus RNA polymerase for detection of virus infection.
Foot-and-Mouth Disease
Multifunctionality of a picornavirus polymerase domain: nuclear localization signal and nucleotide recognition.
Foot-and-Mouth Disease
Mutations that hamper dimerization of foot-and-mouth disease virus 3A protein are detrimental for infectivity.
Foot-and-Mouth Disease
New virus-specific T-helper epitopes of foot-and-mouth disease viral VP1 protein.
Foot-and-Mouth Disease
Novel purification method for recombinant 3AB1 nonstructural protein of foot-and-mouth disease virus for use in differentiation between infected and vaccinated animals.
Foot-and-Mouth Disease
Observations and implications of proteolysis in preparations of foot-and-mouth disease virus.
Foot-and-Mouth Disease
Orientation of epitopes influences the immunogenicity of synthetic peptide dimers.
Foot-and-Mouth Disease
Outer membrane protein PhoE as a carrier for the exposure of foreign antigenic determinants at the bacterial cell surface.
Foot-and-Mouth Disease
Pan-Serotype Diagnostic for Foot-and-Mouth Disease Using the Consensus Antigen of Nonstructural Protein 3B.
Foot-and-Mouth Disease
Peptides Interfering 3A Protein Dimerization Decrease FMDV Multiplication.
Foot-and-Mouth Disease
Phylogenic analysis of serotype Asia1 foot-and-mouth disease virus from Sulaimani/Iraq using VP1 protein: heterogeneity with vaccine strain As1/Shamir/89.
Foot-and-Mouth Disease
PI3K-Akt signaling and viral infection.
Foot-and-Mouth Disease
Polymerase Fidelity Contributes to Foot-and-Mouth Disease Virus Pathogenicity and Transmissibility In Vivo.
Foot-and-Mouth Disease
Production of foot-and-mouth disease virus SAT2 VP1 protein.
Foot-and-Mouth Disease
Purification and identification of the RNA-dependent RNA polymerase of foot-and-mouth disease virus.
Foot-and-Mouth Disease
Purification and immunogenicity of fusion VP1 protein of foot and mouth disease virus.
Foot-and-Mouth Disease
Purification, crystallization and preliminary X-ray crystallographic studies of swine MHC class I complexed with an FMDV CTL epitope Hu64.
Foot-and-Mouth Disease
Radioimmunoassay for detection of VP1 specific neutralizing antibodies of foot and mouth disease virus.
Foot-and-Mouth Disease
Re-emergence of circulatory foot-and-mouth disease virus serotypes Asia1 in Bangladesh and VP1 protein heterogeneity with vaccine strain IND 63/72.
Foot-and-Mouth Disease
Recombinant adenovirus expression of FMDV P1-2A and 3C protein and its immune response in mice.
Foot-and-Mouth Disease
Recombinant fusion protein and DNA vaccines against foot and mouth disease virus infection in guinea pig and swine.
Foot-and-Mouth Disease
Recombinant pseudorabies virus expressing P12A and 3C of FMDV can partially protect piglets against FMDV challenge.
Foot-and-Mouth Disease
Recombination patterns in aphthoviruses mirror those found in other picornaviruses.
Foot-and-Mouth Disease
Recovery of infectious type Asia1 foot-and-mouth disease virus from suckling mice directly inoculated with an RNA polymerase I/II-driven unidirectional transcription plasmid.
Foot-and-Mouth Disease
Repeated exposure to 5D9, an inhibitor of 3D polymerase, effectively limits the replication of foot-and-mouth disease virus in host cells.
Foot-and-Mouth Disease
Residues within the Foot-and-Mouth Disease Virus 3Dpol Nuclear Localization Signal Affect Polymerase Fidelity.
Foot-and-Mouth Disease
Ribavirin-Resistant Variants of Foot-and-Mouth Disease Virus: the Effect of Restricted Quasispecies Diversity on Viral Virulence.
Foot-and-Mouth Disease
RNA-dependent RNA polymerase gene sequence from foot-and-mouth disease virus in Hong Kong.
Foot-and-Mouth Disease
Selection and characterization of RNA aptamers to the RNA-dependent RNA polymerase from foot-and-mouth disease virus.
Foot-and-Mouth Disease
Sequence analysis of the RNA polymerase gene of foot-and-mouth disease virus serotype Asia1.
Foot-and-Mouth Disease
Serological survey for foot-and-mouth disease virus in wildlife in eastern Africa and estimation of test parameters of a nonstructural protein enzyme-linked immunosorbent assay for buffalo.
Foot-and-Mouth Disease
Short hairpin RNA targeted to the highly conserved 2B nonstructural protein coding region inhibits replication of multiple serotypes of foot-and-mouth disease virus.
Foot-and-Mouth Disease
Specific interactions between human integrin alpha v beta 3 and chimeric hepatitis B virus core particles bearing the receptor-binding epitope of foot-and-mouth disease virus.
Foot-and-Mouth Disease
Spermidine stimulation of foot-and-mouth disease virus RNA-dependent RNA polymerase activity.
Foot-and-Mouth Disease
Structure of foot-and-mouth disease virus RNA-dependent RNA polymerase and its complex with a template-primer RNA.
Foot-and-Mouth Disease
Structure-function analysis of mutant RNA-dependent RNA polymerase complexes with VPg.
Foot-and-Mouth Disease
Study of the immunogenicity of different recombinant Mengo viruses expressing HIV1 and SIV epitopes.
Foot-and-Mouth Disease
Synthesis and in-vitro evaluation of 2-amino-4-arylthiazole as inhibitor of 3D polymerase against foot-and-mouth disease (FMD).
Foot-and-Mouth Disease
Synthetic vaccine against foot-and-mouth disease based on a palmitoyl derivative of the VP1 protein 135-159 fragment of the A22 virus strain.
Foot-and-Mouth Disease
T135I substitution in the nonstructural protein 2C enhances foot-and-mouth disease virus replication.
Foot-and-Mouth Disease
The carboxy-terminal half of nonstructural protein 3A is not essential for foot-and-mouth disease virus replication in cultured cell lines.
Foot-and-Mouth Disease
The cell attachment site on foot-and-mouth disease virus includes the amino acid sequence RGD (arginine-glycine-aspartic acid).
Foot-and-Mouth Disease
The crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase in complex with its protein primer VPg confirms the existence of a second VPg binding site on Picornaviridae polymerases.
Foot-and-Mouth Disease
The nucleotide sequence of the structural-protein-coding region of foot-and-mouth disease virus serotype SAT3.
Foot-and-Mouth Disease
The plasmid constructs producing shRNA corresponding to the conserved 3D polymerase of Foot and Mouth Disease virus protects guinea pigs against challenge virus.
Foot-and-Mouth Disease
The position of the heterologous domain can influence the solubility and proteolysis of beta-galactosidase fusion proteins in E. coli.
Foot-and-Mouth Disease
The possible use of native foot-and-mouth disease nonstructural protein 3A in a serological screening test.
Foot-and-Mouth Disease
The potential of retro-inverso peptides as synthetic vaccines.
Foot-and-Mouth Disease
The VP1 S154D mutation of type Asia1 foot-and-mouth disease virus enhances viral replication and pathogenicity.
Foot-and-Mouth Disease
Topology of PhoE porin: the 'eyelet' region.
Foot-and-Mouth Disease
Transient inhibition of foot-and-mouth disease virus replication by siRNAs silencing VP1 protein coding region.
Foot-and-Mouth Disease
Use of a standardized bovine serum panel to evaluate a multiplexed nonstructural protein antibody assay for serological surveillance of foot-and-mouth disease.
Foot-and-Mouth Disease
Use of confocal immunofluorescence microscopy to localize viral nonstructural proteins and potential sites of replication in pigs experimentally infected with foot-and-mouth disease virus.
Foot-and-Mouth Disease
Use of in situ hybridization for the detection of foot-and-mouth disease virus in cell culture.
Foot-and-Mouth Disease
Use of outer membrane protein PhoE as a carrier for the transport of a foreign antigenic determinant to the cell surface of Escherichia coli K-12.
Foot-and-Mouth Disease
VP1 protein of Foot-and-mouth disease virus (FMDV) impairs baculovirus surface display.
Foot-and-Mouth Disease
[Antigenic structure of foot-and-mouth virus. IV. Synthesis and immunogenic properties of new fragments of the VP1 protein of food-and-mouth virus strain A22]
Foot-and-Mouth Disease
[Antigenic structure of the foot-and-mouth disease virus. II. Synthesis of protective peptides from the major immunogenic region of VP1 protein of foot-and-mouth disease virus type A22]
Foot-and-Mouth Disease
[Antigenic structure of the foot-and-mouth virus. VI. Functional segments of the immunodominant region of the VP1 protein of foot-and-mouth virus strains O1K and A22]
Foot-and-Mouth Disease
[Cloning fragments of the RNA polymerase gene of an attenuated variant of the foot-and-mouth disease virus A22]
Foot-and-Mouth Disease
[Comparison of the immunogenic potencies of purified inactivated foot-and-mouth disease virus particles with variable amounts of VP1 protein (author's transl)]
Foot-and-Mouth Disease
[Establishment of BHK-21 cell lines stably expressing FMDV 3Dpol gene by retroviral-mediated gene transfer technique]
Foot-and-Mouth Disease
[Expression and utilization of 3AB nonstructural protein of foot-and-mouth disease virus in Escherichia coli].
Foot-and-Mouth Disease
[Molecular basis of changes in biological properties of foot and mouth disease virus of subtype A22]
Foot-and-Mouth Disease
[Nucleotide sequence of the RNA polymerase gene attenuated by a variant of foot-and-mouth disease virus and its comparison with the virulence of related variants of subtype A22]
Foot-and-Mouth Disease
[Primary structure of the 3'-terminal region of the RNA-polymerase gene in foot-and-mouth virus A22]
Foot-and-Mouth Disease
[Primary structure of the A22 RNA polymerase gene of the foot and mouth disease virus]
Foot-and-Mouth Disease
[Primary structure of the gene for VP1 protein of the foot-and-mouth disease virus of Asia 1 serotype]
Foot-and-Mouth Disease
[Prokaryotic expression and bioreactivity analysis of a major epitope region of 2C with 3AB within non-structural protein of foot-and-mouth disease virus]
Foot-and-Mouth Disease
[Secreted expression of nonstructural protein gene 3ABC of foot-and-mouth disease virus in Sf9 cells and activity analysis]
Foot-and-Mouth Disease
[Study on the DNA vaccine against foot-and-mouth disease virus using the heavy chain constant region of swine IgG as the carrier for peptide epitopes]
Foot-and-Mouth Disease
[Synthesis and immunogenic properties of peptides--fragments of the immunodominant regions of the VP1 protein of the Asia-1 type of foot- and-mouth disease virus]
Foot-and-Mouth Disease
[Synthesis of new fragments of VP1 protein fragments from foot and mouth disease virus type A22. Synthesis of fragments 134-139, 134-145, 140-145, 150-155, and 150-159]
Foot-and-Mouth Disease
[Synthetic immunogenic complexes containing a peptide from the surface protein of the foot-and-mouth disease virus]
Foot-and-Mouth Disease
[Synthetic peptide designs based on immunoactive fragments of the VP1 protein of the foot-and-mouth disease virus strain A22]
Foot-and-Mouth Disease
[Synthetic peptides simulating the protective epitopes of VP1 protein of foot-and-mouth disease virus type O and A]
Foot-and-Mouth Disease
[Use of protease 3c and foot-and-mouth disease virus RNA polymerase hybrid proteins, synthesized in Escherichia coli, for diagnosis]
Fowlpox
Reverse Genetics System for the Avian Coronavirus Infectious Bronchitis Virus.
Fragile X Syndrome
A Drosophila model of Fragile X syndrome exhibits defects in phagocytosis by innate immune cells.
Fragile X Syndrome
A human forebrain organoid model of fragile X syndrome exhibits altered neurogenesis and highlights new treatment strategies.
Fragile X Syndrome
A metabolomic and systems biology perspective on the brain of the fragile X syndrome mouse model.
Fragile X Syndrome
A mouse model of the human Fragile X syndrome I304N mutation.
Fragile X Syndrome
A new function for the fragile X mental retardation protein in regulation of PSD-95 mRNA stability.
Fragile X Syndrome
A novel function for fragile X mental retardation protein in translational activation.
Fragile X Syndrome
A novel role of fragile X mental retardation protein in pre-mRNA alternative splicing through RNA-binding protein 14.
Fragile X Syndrome
A nuclear role for the Fragile X mental retardation protein.
Fragile X Syndrome
Advances in understanding of fragile X pathogenesis and FMRP function, and in identification of X linked mental retardation genes.
Fragile X Syndrome
Analysis of FMRP mRNA target datasets reveals highly associated mRNAs mediated by G-quadruplex structures formed via clustered WGGA sequences.
Fragile X Syndrome
Broadening Roles for FMRP: Big News for Big Potassium (BK) Channels.
Fragile X Syndrome
Cell-type-specific profiling of human cellular models of fragile X syndrome reveal PI3K-dependent defects in translation and neurogenesis.
Fragile X Syndrome
Delayed stabilization of dendritic spines in fragile X mice.
Fragile X Syndrome
Dissecting FMR1, the protein responsible for fragile X syndrome, in its structural and functional domains.
Fragile X Syndrome
Dysregulation and restoration of translational homeostasis in fragile X syndrome.
Fragile X Syndrome
FMRP interferes with the Rac1 pathway and controls actin cytoskeleton dynamics in murine fibroblasts.
Fragile X Syndrome
FMRP phosphorylation reveals an immediate-early signaling pathway triggered by group I mGluR and mediated by PP2A.
Fragile X Syndrome
FMRP regulates miR196a-mediated repression of HOXB8 via interaction with the AGO2 MID domain.
Fragile X Syndrome
FMRP regulates the transition from radial glial cells to intermediate progenitor cells during neocortical development.
Fragile X Syndrome
Fragile mental retardation protein interacts with the RNA-binding protein Caprin1 in neuronal RiboNucleoProtein complexes.
Fragile X Syndrome
Fragile X mental retardation protein (FMRP) and metabotropic glutamate receptor subtype 5 (mGlu5) control stress granule formation in astrocytes.
Fragile X Syndrome
Fragile X mental retardation protein (FMRP) binds specifically to the brain cytoplasmic RNAs BC1/BC200 via a novel RNA-binding motif.
Fragile X Syndrome
Fragile X mental retardation protein (FMRP) interacting proteins exhibit different expression patterns during development.
Fragile X Syndrome
Fragile X mental retardation protein controls gating of the sodium-activated potassium channel Slack.
Fragile X Syndrome
Fragile X mental retardation protein deficiency leads to excessive mGluR5-dependent internalization of AMPA receptors.
Fragile X Syndrome
Fragile X mental retardation protein induces synapse loss through acute postsynaptic translational regulation.
Fragile X Syndrome
Fragile X mental retardation protein is required for synapse elimination by the activity-dependent transcription factor MEF2.
Fragile X Syndrome
Fragile X mental retardation protein regulates accumulation of the active zone protein Munc18-1 in presynapses via local translation in axons during synaptogenesis.
Fragile X Syndrome
Fragile X mental retardation protein shifts between polyribosomes and stress granules after neuronal injury by arsenite stress or in vivo hippocampal electrode insertion.
Fragile X Syndrome
Fragile X protein controls neural stem cell proliferation in the Drosophila brain.
Fragile X Syndrome
Fragile X Syndrome: From molecular pathology to therapy.
Fragile X Syndrome
Glutamate Induces the Elongation of Early Dendritic Protrusions via mGluRs in Wild Type Mice, but Not in Fragile X Mice.
Fragile X Syndrome
Heads-up: New roles for the fragile X mental retardation protein in neural stem and progenitor cells.
Fragile X Syndrome
HITS-CLIP in various brain areas reveals new targets and new modalities of RNA binding by fragile X mental retardation protein.
Fragile X Syndrome
Involvement of FMRP in Primary MicroRNA Processing via Enhancing Drosha Translation.
Fragile X Syndrome
Lost once, the Fragile X Mental Retardation protein is now back onto brain polyribosomes.
Fragile X Syndrome
Metabotropic glutamate receptors and fragile x mental retardation protein: partners in translational regulation at the synapse.
Fragile X Syndrome
Modulation of dendritic spines and synaptic function by Rac1: a possible link to Fragile X syndrome pathology.
Fragile X Syndrome
Neuronal activity drives FMRP- and HSPG-dependent matrix metalloproteinase function required for rapid synaptogenesis.
Fragile X Syndrome
New Insights Into the Role of Cav2 Protein Family in Calcium Flux Deregulation in Fmr1-KO Neurons.
Fragile X Syndrome
On BC1 RNA and the fragile X mental retardation protein.
Fragile X Syndrome
Overexpression of Down syndrome cell adhesion molecule impairs precise synaptic targeting.
Fragile X Syndrome
Persistent astrocyte activation in the fragile X mouse cerebellum.
Fragile X Syndrome
Quantitative profiling of brain lipid raft proteome in a mouse model of fragile X syndrome.
Fragile X Syndrome
Reduced mitochondrial fusion and Huntingtin levels contribute to impaired dendritic maturation and behavioral deficits in Fmr1-mutant mice.
Fragile X Syndrome
RNA and microRNAs in fragile X mental retardation.
Fragile X Syndrome
Roles of fragile X mental retardation protein in dopaminergic stimulation-induced synapse-associated protein synthesis and subsequent alpha-amino-3-hydroxyl-5-methyl-4-isoxazole-4-propionate (AMPA) receptor internalization.
Fragile X Syndrome
S6K1 phosphorylates and regulates fragile X mental retardation protein (FMRP) with the neuronal protein synthesis-dependent mammalian target of rapamycin (mTOR) signaling cascade.
Fragile X Syndrome
Species-dependent posttranscriptional regulation of NOS1 by FMRP in the developing cerebral cortex.
Fragile X Syndrome
Splicing of exon 9a in FMR1 transcripts results in a truncated FMRP with altered subcellular distribution.
Fragile X Syndrome
Targeting the endocannabinoid system in the treatment of fragile X syndrome.
Fragile X Syndrome
The FMRP/GRK4 mRNA interaction uncovers a new mode of binding of the Fragile X mental retardation protein in cerebellum.
Fragile X Syndrome
The fragile X mental retardation protein FMRP binds elongation factor 1A mRNA and negatively regulates its translation in vivo.
Fragile X Syndrome
The fragile X mental retardation protein is a molecular adaptor between the neurospecific KIF3C kinesin and dendritic RNA granules.
Fragile X Syndrome
Trapping of messenger RNA by Fragile X Mental Retardation protein into cytoplasmic granules induces translation repression.
Fragile X Syndrome
Understanding fragile X syndrome: insights from animal models.
Fragile X Syndrome
Widespread Alterations in Translation Elongation in the Brain of Juvenile Fmr1 Knockout Mice.
Fragile X Syndrome
[Fragile X syndrome, a disease caused by defects in an RNA-binding protein]
Frontotemporal Dementia
A conserved role for the ALS-linked splicing factor SFPQ in repression of pathogenic cryptic last exons.
Frontotemporal Dementia
A matter of balance.
Frontotemporal Dementia
Abnormal RNA stability in amyotrophic lateral sclerosis.
Frontotemporal Dementia
Detection of TAR DNA-binding protein 43 (TDP-43) oligomers as initial intermediate species during aggregate formation.
Frontotemporal Dementia
Ectopic expression of Musashi-1 in Alzheimer disease and Pick disease.
Frontotemporal Dementia
Frontotemporal dementia and amyotrophic lateral sclerosis-associated disease protein TDP-43 promotes dendritic branching.
Frontotemporal Dementia
Functional and dynamic polymerization of the ALS-linked protein TDP-43 antagonizes its pathologic aggregation.
Frontotemporal Dementia
FUS affects circular RNA expression in murine embryonic stem cell-derived motor neurons.
Frontotemporal Dementia
FUS contributes to mTOR-dependent inhibition of translation.
Frontotemporal Dementia
Hypertonic Stress Causes Cytoplasmic Translocation of Neuronal, but Not Astrocytic, FUS due to Impaired Transportin Function.
Frontotemporal Dementia
Inter-Species Differences in Regulation of the Progranulin-Sortilin Axis in TDP-43 Cell Models of Neurodegeneration.
Frontotemporal Dementia
Loss of Dynamic RNA Interaction and Aberrant Phase Separation Induced by Two Distinct Types of ALS/FTD-Linked FUS Mutations.
Frontotemporal Dementia
Lysine acetylation regulates the RNA binding, subcellular localization and inclusion formation of FUS.
Frontotemporal Dementia
Mechanisms of TDP-43 Proteinopathy Onset and Propagation.
Frontotemporal Dementia
Molecular structure and interactions within amyloid-like fibrils formed by a low-complexity protein sequence from FUS.
Frontotemporal Dementia
Phosphorylation of the FUS low-complexity domain disrupts phase separation, aggregation, and toxicity.
Frontotemporal Dementia
Quantitative analysis of cryptic splicing associated with TDP-43 depletion.
Frontotemporal Dementia
Specific aromatic foldamers potently inhibit spontaneous and seeded A?42 and A?43 fibril assembly.
Frontotemporal Dementia
Split GFP technologies to structurally characterize and quantify functional biomolecular interactions of FTD-related proteins.
Frontotemporal Dementia
SUMOylation Regulates TDP-43 Splicing Activity and Nucleocytoplasmic Distribution.
Frontotemporal Dementia
TDP-43 and NOVA-1 RNA-binding proteins as competitive splicing regulators of the schizophrenia-associated TNIK gene.
Frontotemporal Dementia
The FTD/ALS-associated RNA-binding protein TDP-43 regulates the robustness of neuronal specification through microRNA-9a in Drosophila.
Frontotemporal Dementia
The RNA-binding motif 45 (RBM45) protein accumulates in inclusion bodies in amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration with TDP-43 inclusions (FTLD-TDP) patients.
Frontotemporal Dementia
Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss.
Frontotemporal Lobar Degeneration
3'UTR Length-Dependent Control of SynGAP Isoform ?2 mRNA by FUS and ELAV-like Proteins Promotes Dendritic Spine Maturation and Cognitive Function.
Frontotemporal Lobar Degeneration
Activity-dependent FUS dysregulation disrupts synaptic homeostasis.
Frontotemporal Lobar Degeneration
Biological Spectrum of Amyotrophic Lateral Sclerosis Prions.
Frontotemporal Lobar Degeneration
Characterizing the RNA targets and position-dependent splicing regulation by TDP-43.
Frontotemporal Lobar Degeneration
FUS regulates genes coding for RNA-binding proteins in neurons by binding to their highly conserved introns.
Frontotemporal Lobar Degeneration
FUS/TLS deficiency causes behavioral and pathological abnormalities distinct from amyotrophic lateral sclerosis.
Frontotemporal Lobar Degeneration
Molecular Dissection of FUS Points at Synergistic Effect of Low-Complexity Domains in Toxicity.
Frontotemporal Lobar Degeneration
Neuron-to-Neuron Transfer of FUS in Drosophila Primary Neuronal Culture Is Enhanced by ALS-Associated Mutations.
Frontotemporal Lobar Degeneration
RBM45 homo-oligomerization mediates association with ALS-linked proteins and stress granules.
Frontotemporal Lobar Degeneration
Severe respiratory changes at end stage in a FUS-induced disease state in adult rats.
Frontotemporal Lobar Degeneration
TBPH/TDP-43 modulates translation of Drosophila futsch mRNA through an UG-rich sequence within its 5'UTR.
Frontotemporal Lobar Degeneration
TDP-43 accelerates deadenylation of target mRNAs by recruiting Caf1 deadenylase.
Frontotemporal Lobar Degeneration
TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration.
Frontotemporal Lobar Degeneration
TDP-43, the signature protein of FTLD-U, is a neuronal activity-responsive factor.
Frontotemporal Lobar Degeneration
The cooperative binding of TDP-43 to GU-rich RNA repeats antagonizes TDP-43 aggregation.
Frontotemporal Lobar Degeneration
The RNA-binding motif 45 (RBM45) protein accumulates in inclusion bodies in amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration with TDP-43 inclusions (FTLD-TDP) patients.
Frontotemporal Lobar Degeneration
The role of FUS gene variants in neurodegenerative diseases.
Frontotemporal Lobar Degeneration
Transposable Elements in TDP-43-Mediated Neurodegenerative Disorders.
Frontotemporal Lobar Degeneration
Variations in the progranulin gene affect global gene expression in frontotemporal lobar degeneration.
Frontotemporal Lobar Degeneration
[Pathomechanisms and clinical aspects of frontotemporal lobar degeneration].
Ganglioglioma
The reelin pathway components disabled-1 and p35 in gangliogliomas--a mutation and expression analysis.
Gastroenteritis
Application of Molecular Dynamics Simulations to the Design of Nucleotide Inhibitors Binding to Norovirus Polymerase.
Gastroenteritis
Comparative in vivo analysis of the nsp15 endoribonuclease of murine, porcine and severe acute respiratory syndrome coronaviruses.
Gastroenteritis
Complete genomic sequences, a key residue in the spike protein and deletions in nonstructural protein 3b of US strains of the virulent and attenuated coronaviruses, transmissible gastroenteritis virus and porcine respiratory coronavirus.
Gastroenteritis
Crystallographic and Biochemical Analysis of Rotavirus NSP2 with Nucleotides Reveals a Nucleoside Diphosphate Kinase-Like Activity.
Gastroenteritis
Design and construction of African swine fever virus chimeras incorporating foreign viral epitopes.
Gastroenteritis
Detection of the norovirus variants GGII.4 hunter and GGIIb/hilversum in Italian children with gastroenteritis.
Gastroenteritis
Effective inhibition of porcine transmissible gastroenteritis virus replication in ST cells by shRNAs targeting RNA-dependent RNA polymerase gene.
Gastroenteritis
Emergence of unique variants and inter-genotype recombinants of human astroviruses infecting infants, children and adults in Kolkata, India.
Gastroenteritis
Etiology of sporadic cases of pediatric acute gastroenteritis in asturias, Spain, and genotyping and characterization of norovirus strains involved.
Gastroenteritis
Gastroenteritis outbreaks associated with Norwalk-like viruses and their investigation by nested RT-PCR.
Gastroenteritis
Genetic polymorphism across regions of the three open reading frames of "Norwalk-like viruses".
Gastroenteritis
Human enteric Caliciviridae: a new prevalent small round-structured virus group defined by RNA-dependent RNA polymerase and capsid diversity.
Gastroenteritis
Immunogenic characterization and epitope mapping of transmissible gastroenteritis virus RNA dependent RNA polymerase.
Gastroenteritis
Insight Into the Interaction Between RNA Polymerase and VPg for Murine Norovirus Replication.
Gastroenteritis
Molecular characterisation of small round structured viruses associated with gastroenteritis in South Africa.
Gastroenteritis
Molecular characterization of partial-open reading frames 1a and 2 of the human astroviruses in South Korea.
Gastroenteritis
Molecular epidemiology of caliciviruses causing outbreaks and sporadic cases of acute gastroenteritis in Spain.
Gastroenteritis
Norovirus RNA-dependent RNA polymerase: A computational study of metal-binding preferences.
Gastroenteritis
Norovirus RNA-dependent RNA-polymerase is phosphorylated by an important survival kinase, Akt.
Gastroenteritis
Porcine transmissible gastroenteritis virus nonstructural protein 2 contributes to inflammation via NF-?B activation.
Gastroenteritis
Putative E3 ubiquitin ligase of human rotavirus inhibits NF-?B activation by using molecular mimicry to target ?-TrCP.
Gastroenteritis
RNA polymerase associated with human rotaviruses in diarrhea stools.
Gastroenteritis
Shutdown of interferon signaling by a viral-hijacked E3 ubiquitin ligase.
Gastroenteritis
Transmissible gastroenteritis coronavirus RNA-dependent RNA polymerase and nonstructural proteins 2, 3, and 8 are incorporated into viral particles.
Gastroenteritis
Viral shedding in gastroenteritis in children caused by variants and novel recombinant norovirus infections.
Gastroenteritis
[Rapid and efficient detection method of Norwalk virus]
Gastroenteritis, Transmissible, of Swine
Effective inhibition of porcine transmissible gastroenteritis virus replication in ST cells by shRNAs targeting RNA-dependent RNA polymerase gene.
Gastroesophageal Reflux
Analysis of transcriptional control of the gerD spore germination gene of Bacillus subtilis 168.
Gastrointestinal Stromal Tumors
High expression of the RNA-binding protein RBPMS2 in gastrointestinal stromal tumors.
Genetic Diseases, Inborn
Mapping the Transcriptome-Wide Landscape of RBP Binding Sites Using gPAR-CLIP-seq: Bioinformatic Analysis.
Genetic Diseases, Inborn
The genetic control of protein synthesis: The haemoglobin model.
Glaucoma
The RNA-binding protein and stress granule component ATAXIN-2 is expressed in mouse and human tissues associated with glaucoma pathogenesis.
Glioblastoma
Antagonism between the RNA-binding protein Musashi1 and miR-137 and its potential impact on neurogenesis and glioblastoma development.
Glioblastoma
Anti-cancer effects of the HuR inhibitor, MS-444, in malignant glioma cells.
Glioblastoma
Eribulin penetrates brain tumor tissue and prolongs survival of mice harboring intracerebral glioblastoma xenografts.
Glioblastoma
MSI2-TGF-?/TGF-? R1/SMAD3 positive feedback regulation in glioblastoma.
Glioblastoma
Musashi1 Impacts Radio-Resistance in Glioblastoma by Controlling DNA-Protein Kinase Catalytic Subunit.
Glioblastoma
RNA-Binding Protein Musashi1 Is a Central Regulator of Adhesion Pathways in Glioblastoma.
Glioblastoma
The oncogenic RNA-binding protein Musashi1 is regulated by HuR via mRNA translation and stability in glioblastoma cells.
Glioblastoma
The RNA-binding protein SERBP1 functions as a novel oncogenic factor in glioblastoma by bridging cancer metabolism and epigenetic regulation.
Glioblastoma
UPF1 regulates the malignant biological behaviors of glioblastoma cells via enhancing the stability of Linc-00313.
Glioma
A Novel Signature Constructed by RNA-Binding Protein Coding Genes to Improve Overall Survival Prediction of Glioma Patients.
Glioma
ANOVA, a putative astrocytic RNA-binding protein gene that maps to chromosome 19q13.3.
Glioma
Augmented therapeutic efficacy of an oncolytic herpes simplex virus type 1 mutant expressing ICP34.5 under the transcriptional control of musashi1 promoter in the treatment of malignant glioma.
Glioma
C/EBP? mediates RNA polymerase III-driven transcription of oncomiR-138 in malignant gliomas.
Glioma
CIRP regulates BEV-induced cell migration in gliomas.
Glioma
Exosomes derived from microRNA-199a-overexpressing mesenchymal stem cells inhibit glioma progression by down-regulating AGAP2.
Glioma
Expression of Progesterone Receptor Membrane Component 1 (PGRMC1), Progestin and AdipoQ Receptor 7 (PAQPR7), and Plasminogen Activator Inhibitor 1 RNA-Binding Protein (PAIRBP1) in Glioma Spheroids In Vitro.
Glioma
Expression of the neural RNA-binding protein Musashi1 in human gliomas.
Glioma
Hu Antigen R (HuR) multimerization contributes to glioma disease progression.
Glioma
Identification of RNA-binding protein LARP4B as a tumor suppressor in glioma.
Glioma
Interplay between PCBP2 and miRNA modulates ARHGDIA expression and function in glioma migration and invasion.
Glioma
Lin28A promotes IRF6-regulated aerobic glycolysis in glioma cells by stabilizing SNHG14.
Glioma
Musashi1 enhances chemotherapy resistance of pediatric glioblastoma cells in vitro.
Glioma
Musashi1, an evolutionarily conserved neural RNA-binding protein, is a versatile marker of human glioma cells in determining their cellular origin, malignancy, and proliferative activity.
Glioma
Persistent infection of a temperature-sensitive G31 vesicular stomatitis virus mutant in neural and nonneural cells: biological and virological characteristics.
Glioma
Prognostic value of Musashi-1 in gliomas.
Glioma
RNA-binding protein Musashi1 modulates glioma cell growth through the post-transcriptional regulation of Notch and PI3 kinase/Akt signaling pathways.
Glioma
RNA-binding protein PCBP2 modulates glioma growth by regulating FHL3.
Glioma
RNA-binding Protein UNR Promotes Glioma Cell Migration and Regulates the Expression of Ribosomal Protein L9.
Glioma
Splicing factors PTBP1 and PTBP2 promote proliferation and migration of glioma cell lines.
Glioma
The histone deacetylase SIRT6 suppresses the expression of the RNA-binding protein PCBP2 in glioma.
Glioma
The RNA-binding protein HuR promotes glioma growth and treatment resistance.
Glioma
The RNA-binding protein SRSF1 is a key cell cycle regulator via stabilizing NEAT1 in glioma.
Glioma
Zika virus NS5 protein inhibits cell growth and invasion of glioma.
Gonadal Dysgenesis
WT1 and kidney progenitor cells.
Granuloma
THE EFFECT OF STEM CELLS AS AN ADJUVANT ON THE IMMUNOGENICITY OF A POTENTIAL ANTI-SCHISTOSOMAL VACCINE IN MICE.
Hand, Foot and Mouth Disease
Expression of enterovirus 71 capsid protein VP1 in Escherichia coli and its clinical application.
Hand, Foot and Mouth Disease
GITRL as a genetic adjuvant enhances enterovirus 71 VP1 DNA vaccine immunogenicity.
Head and Neck Neoplasms
RNA-Binding Protein La Mediates TGF?-Induced Epithelial to Mesenchymal Transition and Cancer Stem Cell Properties.
Heart Arrest
The Value of Extracellular Cold-Inducible RNA-Binding Protein (eCIRP) in Predicting the Severity and Prognosis of Patients After Cardiac Arrest: A Preliminary Observational Study.
Heart Arrest
Therapeutic Hypothermia Enhances Cold-Inducible RNA-Binding Protein Expression and Inhibits Mitochondrial Apoptosis in a Rat Model of Cardiac Arrest.
Heart Diseases
Increased Cardiac Arrhythmogenesis Associated With Gap Junction Remodeling With Upregulation of RNA-Binding Protein FXR1.
Heart Failure
CELF1 promotes vascular endothelial growth factor degradation resulting in impaired microvasculature in heart failure.
Heart Failure
Rbm20-deficient cardiogenesis reveals early disruption of RNA processing and sarcomere remodeling establishing a developmental etiology for dilated cardiomyopathy.
Heart Failure
RNA-binding protein RBM20 represses splicing to orchestrate cardiac pre-mRNA processing.
Heart Failure
Titin Forms Circles: Regulation by Heart Failure and the RNA-Binding Protein RBM20.
Hematologic Diseases
Enhancement of LIN28B-induced hematopoietic reprogramming by IGF2BP3.
Hematologic Neoplasms
Che-1 is targeted by c-Myc to sustain proliferation in pre-B-cell acute lymphoblastic leukemia.
Hemophilia A
Hepatitis C virus infection in children with hemophilia: characterization of antibody response to four different antigens and relationship of antibody response, viremia, and hepatic dysfunction.
Hemorrhagic Fever with Renal Syndrome
Primary structure of the large (L) RNA segment of nephropathia epidemica virus strain Hällnäs B1 coding for the viral RNA polymerase.
Hemorrhagic Fever, Crimean
Crimean-Congo Hemorrhagic Fever Virus Suppresses Innate Immune Responses via a Ubiquitin and ISG15 Specific Protease.
Hemorrhagic Fever, Crimean
Crimean-Congo hemorrhagic fever virus-encoded ovarian tumor (OTU) protease activity is dispensable for virus RNA polymerase function.
Hemorrhagic Fever, Crimean
In silico structural elucidation of RNA-dependent RNA polymerase towards the identification of potential Crimean-Congo Hemorrhagic Fever Virus inhibitors.
Hemorrhagic Fever, Crimean
Next-generation sequencing of southern African Crimean-Congo haemorrhagic fever virus isolates reveals a high frequency of M segment reassortment.
Hemorrhagic Fever, Ebola
Ribavirin does not potentiate favipiravir antiviral activity against Ebola virus in non-human primates.
Hemorrhagic Septicemia
Virion RNA polymerases of two salmonid rhabdoviruses.
Hemorrhagic Septicemia, Viral
A single amino acid mutation (I1012F) of the RNA polymerase of marine viral hemorrhagic septicemia virus changes the in vitro virulence to rainbow trout gill epithelial cells.
Hemorrhagic Septicemia, Viral
Expression profiling, immune functions, and molecular characteristics of the tetraspanin molecule CD63 from Amphiprion clarkii.
Hepatitis
(1)H, (13)C, (15)N resonance assignments of murine hepatitis virus nonstructural protein 3a.
Hepatitis
Analysis of hepatitis A virus protein 2B in sera of hepatitis A of various severities.
Hepatitis
Aquarius, a novel gene isolated by gene trapping with an RNA-dependent RNA polymerase motif.
Hepatitis
B lymphocyte and macrophage expression of carcinoembryonic antigen-related adhesion molecules that serve as receptors for murine coronavirus.
Hepatitis
Bovine Coronavirus nsp1 (p28) is an RNA Binding Protein that Binds Terminal Genomic Cis-Replication Elements.
Hepatitis
Characterization by mass spectrometry of a recombinant hepatitis delta virus antigen and its proteolytic products.
Hepatitis
Characterization of monoclonal antibodies against duck hepatitis type 1 virus VP1 protein.
Hepatitis
Characterization of the expression, intracellular localization, and replication complex association of the putative mouse hepatitis virus RNA-dependent RNA polymerase.
Hepatitis
Characterization of the phosphorylated forms and the phosphorylated residues of hepatitis delta virus delta antigens.
Hepatitis
Characterization of two RNA polymerase activities induced by mouse hepatitis virus.
Hepatitis
Comparative in vivo analysis of the nsp15 endoribonuclease of murine, porcine and severe acute respiratory syndrome coronaviruses.
Hepatitis
Comparison of genomic and predicted amino acid sequences of respiratory and enteric bovine coronaviruses isolated from the same animal with fatal shipping pneumonia.
Hepatitis
Complete sequence (20 kilobases) of the polyprotein-encoding gene 1 of transmissible gastroenteritis virus.
Hepatitis
Crystallization and structure determination of a hepatitis delta virus ribozyme: use of the RNA-binding protein U1A as a crystallization module.
Hepatitis
Development of an improved dual-promoter-based reverse genetics system for emerging Senecavirus A.
Hepatitis
Direct investigation of protein RNA-binding domains using digoxigenin-labelled RNAs and synthetic peptides: application to the hepatitis delta antigen.
Hepatitis
Dissection of amino-terminal functional domains of murine coronavirus nonstructural protein 3.
Hepatitis
Dynamics of coronavirus replication-transcription complexes.
Hepatitis
Emerging antiviral drugs.
Hepatitis
Evaluation of hepatitis delta virus RNA levels during interferon therapy by analysis of polymerase chain reaction products with a nonradioisotopic hybridization assay.
Hepatitis
Follow-up study of anti-hepatitis C virus antibodies in blood donors implicated in post-transfusion non-A, non-B hepatitis.
Hepatitis
Further characterization of mouse hepatitis virus RNA-dependent RNA polymerases.
Hepatitis
HCV RNA-dependent RNA polymerase replicates in vitro the 3' terminal region of the minus-strand viral RNA more efficiently than the 3' terminal region of the plus RNA.
Hepatitis
Hepatitis C virus of subtype 2l in marseille, southeastern france.
Hepatitis
Homology-Based Identification of a Mutation in the Coronavirus RNA-Dependent RNA Polymerase That Confers Resistance to Multiple Mutagens.
Hepatitis
Host RNA polymerase requirements for transcription of the human hepatitis delta virus genome.
Hepatitis
Human transcription elongation factor NELF: identification of novel subunits and reconstitution of the functionally active complex.
Hepatitis
Identification and analysis of MHV-A59 P28 cleavage site.
Hepatitis
Identification and characterization of severe acute respiratory syndrome coronavirus replicase proteins.
Hepatitis
Identification and stability of a 30-kDa nonstructural protein encoded by mRNA 2 of mouse hepatitis virus in infected cells.
Hepatitis
Identification of mouse hepatitis virus papain-like proteinase 2 activity.
Hepatitis
Identification of putative polymerase gene product in cells infected with murine coronavirus A59.
Hepatitis
Identification of the murine coronavirus p28 cleavage site.
Hepatitis
Immune response to a hepatitis C virus nonstructural protein in chronic hepatitis C virus infection.
Hepatitis
Improvement of hepatitis C virus RNA polymerase chain reaction through a multicentre quality control study. French Study Group for the Standardization of Hepatitis C Virus PCR.
Hepatitis
In situ enzymatic oligonucleotide amplification of hepatitis C virus-RNA in liver biopsy specimens (reverse transcriptase in situ polymerase chain reaction) after orthotopic liver transplantation for hepatitis C-related liver disease.
Hepatitis
Maturation of the polymerase polyprotein of the coronavirus MHV strain JHM involves a cascade of proteolytic processing events.
Hepatitis
Mobility and interactions of the coronavirus nonstructural protein 4.
Hepatitis
Mouse hepatitis virus strain A59 RNA polymerase gene ORF 1a: heterogeneity among MHV strains.
Hepatitis
Murine coronaviruses encoding nsp2 at different genomic loci have altered replication, protein expression, and localization.
Hepatitis
New antiviral target revealed by the hexameric structure of mouse hepatitis virus nonstructural protein nsp15.
Hepatitis
Nucleotide Analogues as Inhibitors of SARS-CoV-2 Polymerase.
Hepatitis
Nucleotide sequence of the human coronavirus 229E RNA polymerase locus.
Hepatitis
Organ-specific attenuation of murine hepatitis virus strain A59 by replacement of catalytic residues in the putative viral cyclic phosphodiesterase ns2.
Hepatitis
Processing of the coronavirus MHV-JHM polymerase polyprotein: identification of precursors and proteolytic products spanning 400 kilodaltons of ORF1a.
Hepatitis
Protection against yellow fever in monkeys by immunization with yellow fever virus nonstructural protein NS1.
Hepatitis
Protein-Encoding RNA to RNA Information Transfer in Mammalian Cells: RNA-dependent mRNA Amplification. Identification of Chimeric RNA Intermediates and Putative RNA End Products.
Hepatitis
Recombinant VP1 protein of duck hepatitis virus 1 expressed in Pichia pastoris and its immunogenicity in ducks.
Hepatitis
Rescue of tomato spotted wilt virus entirely from complementary DNA clones.
Hepatitis
RNA replication without RNA-dependent RNA polymerase: surprises from hepatitis delta virus.
Hepatitis
RNA-binding activity of hepatitis delta antigen involves two arginine-rich motifs and is required for hepatitis delta virus RNA replication.
Hepatitis
RNA-dependent Amplification of Mammalian mRNA Encoding Extracellullar Matrix Proteins: Identification of Chimeric RNA Intermediates for ?1, ?1, and ?1 Chains of Laminin.
Hepatitis
RNA-templated replication of hepatitis delta virus: genomic and antigenomic RNAs associate with different nuclear bodies.
Hepatitis
Search for antisense copies of beta-globin mRNA in anemic mouse spleen.
Hepatitis
Sequence and expression analysis of potential nonstructural proteins of 4.9, 4.8, 12.7, and 9.5 kDa encoded between the spike and membrane protein genes of the bovine coronavirus.
Hepatitis
Serodiagnosis of hepatitis C virus (HCV) infection with an HCV core protein molecularly expressed by a recombinant baculovirus.
Hepatitis
Stable expression of hepatitis delta virus antigen in a eukaryotic cell line.
Hepatitis
Synthesis of virus-specific RNA in permeabilized murine coronavirus-infected cells.
Hepatitis
The complete sequence (22 kilobases) of murine coronavirus gene 1 encoding the putative proteases and RNA polymerase.
Hepatitis
The fitness of defective interfering murine coronavirus DI-a and its derivatives is decreased by nonsense and frameshift mutations.
Hepatitis
The Interaction between the RNA-Dependent RNA-Polymerase of the Hepatitis Virus and RNA Matrices.
Hepatitis
Tissue hepatitis C virus RNA quantification and protein expression help identify early hepatitis C virus recurrence after liver transplantation.
Hepatitis
Translation and processing of mouse hepatitis virus virion RNA in a cell-free system.
Hepatitis
Use and interpretation of HCV diagnostic tests in the clinical setting.
Hepatitis
Viral replication. Structural basis for RNA replication by the hepatitis C virus polymerase.
Hepatitis
Viroids: self-replicating, mobile, and fast-evolving noncoding regulatory RNAs.
Hepatitis
Whole-genome analysis of genetic recombination of hepatitis delta virus: molecular domain in delta antigen determining trans-activating efficiency.
Hepatitis
[A clinical analysis of twelve patients with Galerina autumnalis poisoning]
Hepatitis
[Expression of VP1 gene and ELISA detection of antibodies against duck hepatitis virus]
Hepatitis
[Viral hepatitis B und C.]
Hepatitis A
A comparative volatilomic characterization of Florence fennel from different locations: antiviral prospects.
Hepatitis A
Acute hepatitis A virus infection in Turkey.
Hepatitis A
Altered hepatitis A VP1 protein resulting from cell culture propagation of virus.
Hepatitis A
Analysis of hepatitis A virus protein 2B in sera of hepatitis A of various severities.
Hepatitis A
Competitor template RNA for detection and quantitation of hepatitis A virus by PCR.
Hepatitis A
Detection of hepatitis A virus RNA and capsid antigen in individual cells.
Hepatitis A
Determinants in 3Dpol modulate the rate of growth of hepatitis A virus.
Hepatitis A
Development and evaluation of an indirect ELISA based on recombinant nonstructural protein 3A to detect antibodies to duck hepatitis A virus type 1.
Hepatitis A
Hepatitis E virus-associated aplastic anaemia: the first case of its kind.
Hepatitis A
High yield expression of duck hepatitis A virus VP1 protein in Escherichia coli, and production and characterization of polyclonal antibody.
Hepatitis A
Identification of a Conserved B-Cell Epitope on Duck Hepatitis A Type 1 Virus VP1 Protein.
Hepatitis A
Importance of amino acid 216 in nonstructural protein 2B for replication of hepatitis A virus in cell culture and in vivo.
Hepatitis A
Internal initiation sites of de novo RNA synthesis within the hepatitis C virus polypyrimidine tract.
Hepatitis A
Molecular evolution of hepatitis A virus: a new classification based on the complete VP1 protein.
Hepatitis A
Oral vaccine of recombinant Lactococcus lactis expressing the VP1 protein of duck hepatitis A virus type 3 induces mucosal and systemic immune responses.
Hepatitis A
Production of infectious hepatitis C virus by using RNA polymerase I-mediated transcription.
Hepatitis A
Recombinant VP1 protein as a potential marker for the diagnosis of acute hepatitis A virus infection.
Hepatitis A
Sequence analysis of hepatitis A virus cDNA coding for capsid proteins and RNA polymerase.
Hepatitis A
Signals in hepatitis A virus P3 region proteins recognized by the ubiquitin-mediated proteolytic system.
Hepatitis A
The 3D protein of duck hepatitis A virus type 1 binds to a viral genomic 3' UTR and shows RNA-dependent RNA polymerase activity.
Hepatitis A
Variations in genome fragments coding for RNA polymerase in human and simian hepatitis A viruses.
Hepatitis A
[A model of the secondary structure and distribution of antigenic determinants in the VP1 protein of hepatitis A virus]
Hepatitis B
A sensitive procedure for mapping the boundaries of RNA elements binding in vitro translated proteins defines a minimal hepatitis B virus encapsidation signal.
Hepatitis B
Approved Antiviral Drugs over the Past 50 Years.
Hepatitis B
cDNA encoding a chicken protein (CRP1) with homology to hnRNP type A/B.
Hepatitis B
Chimeric hepatitis B virus core particles as probes for studying peptide-integrin interactions.
Hepatitis B
Cluster of differentiation 4+ T-cell counts and human immunodeficiency virus-1 viral load in patients coinfected with hepatitis B virus and hepatitis C virus.
Hepatitis B
Complete nucleotide sequence of the nucleoprotein gene from the human influenza strain A/PR/8/34 (HON1).
Hepatitis B
Critical role of the 36-nucleotide insertion in hepatitis B virus genotype G in core protein expression, genome replication, and virion secretion.
Hepatitis B
Effect of mutation in the hepatitis C virus nonstructural 5B region on HCV replication.
Hepatitis B
Emerging antiviral drugs.
Hepatitis B
Entecavir treatment may be associated with decreased libido in male patients with chronic hepatitis B: report of two cases.
Hepatitis B
Functional characterization of the interaction between human La and hepatitis B virus RNA.
Hepatitis B
HBx protein of hepatitis B virus interacts with the C-terminal portion of a novel human proteasome alpha-subunit.
Hepatitis B
Hepatitis B virus Core protein nuclear interactome identifies SRSF10 as a host RNA-binding protein restricting HBV RNA production.
Hepatitis B
Hepatitis B virus X protein induces RNA polymerase III-dependent gene transcription and increases cellular TATA-binding protein by activating the Ras signaling pathway.
Hepatitis B
Hepatitis B virus X protein promotes interleukin-7 receptor expression via NF-?B and Notch1 pathway to facilitate proliferation and migration of hepatitis B virus-related hepatoma cells.
Hepatitis B
Hepatitis G virus infection in patients with hepatocellular carcinoma in Recife, Brazil.
Hepatitis B
Incorporation of deoxyribonucleotides and ribonucleotides by a dNTP-binding cleft mutated reverse transcriptase in hepatitis B virus core particles.
Hepatitis B
Inhibition of duck hepatitis B virus replication by 2',3'-dideoxycytidine. A potent inhibitor of reverse transcriptase.
Hepatitis B
On the early emergence of reverse transcription: theoretical basis and experimental evidence.
Hepatitis B
Phosphorylation of human La protein at Ser 366 by casein kinase II contributes to hepatitis B virus replication and expression in vitro.
Hepatitis B
Proteolytic processing of the hepatitis B virus e antigen precursor. Cleavage at two furin consensus sequences.
Hepatitis B
RBMY, a male germ cell-specific RNA-binding protein, activated in human liver cancers and transforms rodent fibroblasts.
Hepatitis B
Regulation of RNA polymerase I-dependent promoters by the hepatitis B virus X protein via activated Ras and TATA-binding protein.
Hepatitis B
Specific interactions between human integrin alpha v beta 3 and chimeric hepatitis B virus core particles bearing the receptor-binding epitope of foot-and-mouth disease virus.
Hepatitis B
The impact of hepatitis C virus viremia on renal graft and patient survival: a 9-year prospective study.
Hepatitis B
The Long-Term Effect of Hepatitis C Virus on the Outcome of Live-Donor Kidney Transplant Recipients. A Retrospective Study.
Hepatitis B, Chronic
Factors Contributing to the Antiviral Effectiveness of Tenofovir.
Hepatitis C
"Inapparent" hepatitis B virus infection and hepatitis C virus replication in alcoholic subjects with and without liver disease.
Hepatitis C
1,5-Benzodiazepine inhibitors of HCV NS5B polymerase.
Hepatitis C
1,5-benzodiazepines, a novel class of hepatitis C virus polymerase nonnucleoside inhibitors.
Hepatitis C
12 Weeks of a Ribavirin-Free Sofosbuvir and Nonstructural Protein 5A Inhibitor Regimen Is Enough to Treat Recurrence of Hepatitis C After Liver Transplantation.
Hepatitis C
178 Dual allosteric inhibitors jointly modulate structure and dynamics in the Hepatitis C Virus polymerase.
Hepatitis C
1a/1b subtype profiling of nonnucleoside polymerase inhibitors of hepatitis C virus.
Hepatitis C
2'-Deoxy-2'-spirocyclopropylcytidine Revisited: A New and Selective Inhibitor of the Hepatitis C Virus NS5B Polymerase.
Hepatitis C
2'-deoxy-4'-azido nucleoside analogs are highly potent inhibitors of hepatitis C virus replication despite the lack of 2'-alpha-hydroxyl groups.
Hepatitis C
2-(2-Thienyl)-5,6-dihydroxy-4-carboxypyrimidines as inhibitors of the hepatitis C virus NS5B polymerase: discovery, SAR, modeling, and mutagenesis.
Hepatitis C
2-(3-Thienyl)-5,6-dihydroxypyrimidine-4-carboxylic acids as inhibitors of HCV NS5B RdRp.
Hepatitis C
2-Heteroarylimino-5-arylidene-4-thiazolidinones as a new class of non-nucleoside inhibitors of HCV NS5B polymerase.
Hepatitis C
2-Hydroxy-1-oxo-1,2-dihydroisoquinoline-3-carboxylic acid with Inbuilt ?-N-hydroxy-?-keto-acid pharmacophore as HCV NS5B polymerase inhibitors.
Hepatitis C
2D and 3D quantitative structure-activity relationship study of hepatitis C virus NS5B polymerase inhibitors by comparative molecular field analysis and comparative molecular similarity indices analysis methods.
Hepatitis C
3'-Deoxy phosphoramidate dinucleosides as improved inhibitors of hepatitis C virus subgenomic replicon and NS5B polymerase activity.
Hepatitis C
3-(1,1-dioxo-2H-(1,2,4)-benzothiadiazin-3-yl)-4-hydroxy-2(1H)-quinolinones, potent inhibitors of hepatitis C virus RNA-dependent RNA polymerase.
Hepatitis C
3D Molecular Modelling Study of the H7N9 RNA-Dependent RNA Polymerase as an Emerging Pharmacological Target.
Hepatitis C
3D QSAR and molecular docking studies of benzimidazole derivatives as hepatitis C virus NS5B polymerase inhibitors.
Hepatitis C
4-Thiazolidinones: a novel class of hepatitis C virus NS5B polymerase inhibitors.
Hepatitis C
A cell-based reporter assay for inhibitor screening of hepatitis C virus RNA-dependent RNA polymerase.
Hepatitis C
A cell-permeable hairpin peptide inhibits hepatitis C viral nonstructural protein 5A-mediated translation and virus production.
Hepatitis C
A cellular RNA-binding protein enhances internal ribosomal entry site-dependent translation through an interaction downstream of the hepatitis C virus polyprotein initiation codon.
Hepatitis C
A cis-acting replication element in the sequence encoding the NS5B RNA-dependent RNA polymerase is required for hepatitis C virus RNA replication.
Hepatitis C
A Complex Network of Interactions between S282 and G283 of Hepatitis C Virus Nonstructural Protein 5B and the Template Strand Affects Susceptibility to Sofosbuvir and Ribavirin.
Hepatitis C
A Conserved Tandem Cyclophilin-Binding Site in Hepatitis C Virus Nonstructural Protein 5A Regulates Alisporivir Susceptibility.
Hepatitis C
A continuous nonradioactive assay for RNA-dependent RNA polymerase activity.
Hepatitis C
A Cyclic Phosphoramidate Prodrug of 2'-deoxy-2'-fluoro-2'-C-methylguanosine for the Treatment of Dengue Infection.
Hepatitis C
A fluorescence-based high-throughput screen to identify small compound inhibitors of the genotype 3a hepatitis C virus RNA polymerase.
Hepatitis C
A hepatitis C virus-encoded, nonstructural protein (NS3) triggers dysfunction and apoptosis in lymphocytes: role of NADPH oxidase-derived oxygen radicals.
Hepatitis C
A highly efficient, asymmetric synthesis of benzothiadiazine-substituted tetramic acids: potent inhibitors of hepatitis C virus RNA-dependent RNA polymerase.
Hepatitis C
A homogeneous, solid-phase assay for hepatitis C virus RNA-dependent RNA polymerase.
Hepatitis C
A locking mechanism regulates RNA synthesis and host protein interaction by the hepatitis C virus polymerase.
Hepatitis C
A mini-review on sofosbuvir and daclatasvir treatment in coronavirus disease 2019.
Hepatitis C
A nonisotopic assay method for hepatitis C virus NS5B polymerase.
Hepatitis C
A Novel Class of Highly Potent Irreversible Hepatitis C Virus NS5B Polymerase Inhibitors.
Hepatitis C
A novel hepatitis C virus NS5B polymerase assay of de novo initiated RNA synthesis directed from a heteropolymeric RNA template.
Hepatitis C
A novel mechanism to ensure terminal initiation by hepatitis C virus NS5B polymerase.
Hepatitis C
A Novel Promising Therapeutic Option Against Hepatitis C Virus: An Oral Nucleotide NS5B Polymerase Inhibitor Sofosbuvir.
Hepatitis C
A novel recombinant single-chain hepatitis C virus NS3-NS4A protein with improved helicase activity.
Hepatitis C
A Proline-Tryptophan Turn in the Intrinsically Disordered Domain 2 of NS5A Protein Is Essential for Hepatitis C Virus RNA Replication.
Hepatitis C
A quantitative high-resolution genetic profile rapidly identifies sequence determinants of hepatitis C viral fitness and drug sensitivity.
Hepatitis C
A recombinant hepatitis C virus RNA-dependent RNA polymerase capable of copying the full-length viral RNA.
Hepatitis C
A relaxed discrimination of 2'-O-methyl-GTP relative to GTP between de novo and Elongative RNA synthesis by the hepatitis C RNA-dependent RNA polymerase NS5B.
Hepatitis C
A replicon-based shuttle vector system for assessing the phenotype of HCV NS5B polymerase genes isolated from patient populations.
Hepatitis C
A retrospective case-control study of hepatitis C virus infection and oral lichen planus in Japan: association study with mutations in the core and NS5A region of hepatitis C virus.
Hepatitis C
A review on an update of NS5B polymerase hepatitis C virus inhibitors.
Hepatitis C
A screen for novel hepatitis C virus RdRp inhibitor identifies a broad-spectrum antiviral compound.
Hepatitis C
A search for hepatitis C virus polymerase chain reaction-positive but seronegative subjects among blood donors with elevated alanine aminotransferase.
Hepatitis C
A simple, effective approach for rapid development of high-throughput and reliable LC-MS/MS bioanalytical assays.
Hepatitis C
A single-amino-acid mutation in hepatitis C virus NS5A disrupting FKBP8 interaction impairs viral replication.
Hepatitis C
A time-resolved, internally quenched fluorescence assay to characterize inhibition of hepatitis C virus nonstructural protein 3-4A protease at low enzyme concentrations.
Hepatitis C
A validated LC-MS/MS method for the simultaneous determination of BMS-791325, a hepatitis C virus NS5B RNA polymerase inhibitor, and its metabolite in plasma.
Hepatitis C
Activation of protein kinase R by hepatitis C virus RNA-dependent RNA polymerase.
Hepatitis C
Activation of RNA polymerase I transcription by hepatitis C virus core protein.
Hepatitis C
Active site inhibitors of HCV NS5B polymerase. The development and pharmacophore of 2-thienyl-5,6-dihydroxypyrimidine-4-carboxylic acid.
Hepatitis C
Activity of a potent hepatitis C virus polymerase inhibitor in the chimpanzee model.
Hepatitis C
Activity of Selected Nucleoside Analogue ProTides against Zika Virus in Human Neural Stem Cells.
Hepatitis C
Addition of ribavirin to daclatasvir plus asunaprevir for chronic hepatitis C 1b patients with baseline NS5A resistance-associated variants improved response.
Hepatitis C
Advances in the development of new therapeutic agents targeting the NS3-4A serine protease or the NS5B RNA-dependent RNA polymerase of the hepatitis C virus.
Hepatitis C
All three domains of the hepatitis C virus nonstructural NS5A protein contribute to RNA binding.
Hepatitis C
Allosteric heat shock protein 70 inhibitors block hepatitis C virus assembly.
Hepatitis C
Allosteric inhibition of the hepatitis C virus NS5B polymerase: in silico strategies for drug discovery and development.
Hepatitis C
Allosteric inhibition of the hepatitis C virus NS5B RNA dependent RNA polymerase.
Hepatitis C
Allosteric inhibitors have distinct effects, but also common modes of action, in the HCV polymerase.
Hepatitis C
Allosteric inhibitors of hepatitis C virus NS5B polymerase thumb domain site II: structure-based design and synthesis of new templates.
Hepatitis C
Allosteric mechanism of cyclopropylindolobenzazepine inhibitors for HCV NS5B RdRp via dynamic correlation network analysis.
Hepatitis C
Amino Acid Substitutions in Genotype 3a Hepatitis C Virus Polymerase Protein Affect Responses to Sofosbuvir.
Hepatitis C
Amplification and sequencing of the hepatitis C virus NS3/4A protease and the NS5B polymerase regions for genotypic resistance detection of clinical isolates of subtypes 1a and 1b.
Hepatitis C
An amino-terminal amphipathic alpha-helix mediates membrane association of the hepatitis C virus nonstructural protein 5A.
Hepatitis C
An efficient colorimetric assay for RNA synthesis by viral RNA-dependent RNA polymerases, using thermostable pyrophosphatase.
Hepatitis C
An efficient, asymmetric solid-phase synthesis of benzothiadiazine-substituted tetramic acids: potent inhibitors of the hepatitis C virus RNA-dependent RNA polymerase.
Hepatitis C
An in vitro coupled transcription/translation reporter system for hepatitis C virus RNA-dependent RNA polymerase.
Hepatitis C
An Integrative Drug Repurposing Pipeline: Switching Viral Drugs to Breast Cancer.
Hepatitis C
An interferon lambda 4-associated variant in the hepatitis C virus RNA polymerase affects viral replication in infected cells.
Hepatitis C
An objective assessment of conformational variability in complexes of hepatitis C virus polymerase with non-nucleoside inhibitors.
Hepatitis C
An RNA-binding protein, hnRNP A1, and a scaffold protein, septin 6, facilitate hepatitis C virus replication.
Hepatitis C
Analysis of drug-resistance-associated mutations and genetic barriers in hepatitis C virus NS5B sequences in China.
Hepatitis C
Analysis of Naturally Occurring Resistance-Associated Variants to NS3/4A Protein Inhibitors, NS5A Protein Inhibitors, and NS5B Polymerase Inhibitors in Patients With Chronic Hepatitis C.
Hepatitis C
Analysis of the Resistance of Hepatitis C Virus NS5B Polymerase Inhibitors via Docking and Molecular Dynamics Simulation.
Hepatitis C
Anti-hepatitis C virus activity of novel beta-d-2'-C-methyl-4'-azido pyrimidine nucleoside phosphoramidate prodrugs.
Hepatitis C
Antigenic heterogeneity of the hepatitis C virus NS5A protein.
Hepatitis C
Antiviral activity and mode of action of TMC647078, a novel nucleoside inhibitor of the hepatitis C virus NS5B polymerase.
Hepatitis C
Antiviral Activity of Substituted Salicylanilides - A Review.
Hepatitis C
Antiviral activity of the hepatitis C virus polymerase inhibitor filibuvir in genotype 1-infected patients.
Hepatitis C
Antiviral Activity, Safety, and Tolerability of Multiple Ascending Doses of Elbasvir or Grazoprevir in Participants Infected With Hepatitis C Virus Genotype-1 or -3.
Hepatitis C
Antiviral effect of human recombinant interleukin-12 in patients infected with hepatitis C virus.
Hepatitis C
Antiviral Effect, Safety, and Pharmacokinetics of Five-Day Oral Administration of Deleobuvir (BI 207127), an Investigational Hepatitis C Virus RNA Polymerase Inhibitor, in Patients with Chronic Hepatitis C.
Hepatitis C
Antiviral effects of the interferon-induced protein guanylate binding protein 1 and its interaction with the hepatitis C virus NS5B protein.
Hepatitis C
Antiviral suppression vs restoration of RIG-I signaling by hepatitis C protease and polymerase inhibitors.
Hepatitis C
Apolipoprotein E interacts with hepatitis C virus nonstructural protein 5A and determines assembly of infectious particles.
Hepatitis C
Approaching a new era for hepatitis C virus therapy: inhibitors of the NS3-4A serine protease and the NS5B RNA-dependent RNA polymerase.
Hepatitis C
Approved Antiviral Drugs over the Past 50 Years.
Hepatitis C
Arresting initiation of hepatitis C virus RNA synthesis using heterocyclic derivatives.
Hepatitis C
Aryl uracil inhibitors of hepatitis C virus NS5B polymerase: synthesis and characterization of analogs with a fused 5,6-bicyclic ring motif.
Hepatitis C
Assembly, purification and pre-steady-state kinetic analysis of an active RNA-dependent RNA polymerase elongation complex.
Hepatitis C
Assessment of hepatitis C virus RNA levels by quantitative competitive RNA polymerase chain reaction: high-titer viremia correlates with advanced stage of disease.
Hepatitis C
Association between interleukin 28B polymorphism and sustained virological response to sofosbuvir plus daclatasvir in chronic hepatitis C genotype 4 Egyptian patients.
Hepatitis C
Association of amino acid substitution pattern in nonstructural protein 5A of hepatitis C virus genotype2a low viral load and response to interferon monotherapy.
Hepatitis C
Asunaprevir plus daclatasvir for the treatment of chronic hepatitis C virus infection.
Hepatitis C
Autoantibodies and Autoimmune Disease During Treatment of Children With Chronic Hepatitis C.
Hepatitis C
Autophagy protein ATG5 interacts transiently with the hepatitis C virus RNA polymerase (NS5B) early during infection.
Hepatitis C
B-ring modified aurones as promising allosteric inhibitors of hepatitis C virus RNA-dependent RNA polymerase.
Hepatitis C
Back-priming mode of phi6 RNA-dependent RNA polymerase.
Hepatitis C
Bacteriophage phi 6 RNA-dependent RNA polymerase: molecular details of initiating nucleic acid synthesis without primer.
Hepatitis C
Balapiravir plus peginterferon alfa-2a (40KD)/ribavirin in a randomized trial of hepatitis C genotype 1 patients.
Hepatitis C
Baseline Polymorphisms and Emergence of Drug Resistance in the NS3/4A Protease of Hepatitis C Virus Genotype 1 following Treatment with Faldaprevir and Pegylated Interferon Alpha 2a/Ribavirin in Phase 2 and Phase 3 Studies.
Hepatitis C
Benzimidazole derivatives bearing substituted biphenyls as hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitors: structure-activity relationship studies and identification of a potent and highly selective inhibitor JTK-109.
Hepatitis C
Benzimidazole inhibitors of hepatitis C virus NS5B polymerase: Identification of 2-[(4-diarylmethoxy)phenyl]-benzimidazole.
Hepatitis C
Berberis lyceum and Fumaria indica: in vitro cytotoxicity, antioxidant activity, and in silico screening of their selected phytochemicals as novel hepatitis C virus nonstructural protein 5A inhibitors.
Hepatitis C
Beyond Members of the Flaviviridae Family, Sofosbuvir Also Inhibits Chikungunya Virus Replication.
Hepatitis C
Beyond sofosbuvir: what opportunity exists for a better nucleoside/nucleotide to treat hepatitis C?
Hepatitis C
Binding mode determination of benzimidazole inhibitors of the hepatitis C virus RNA polymerase by a structure and dynamics strategy.
Hepatitis C
Binding site characterization and resistance to a class of non-nucleoside inhibitors of the hepatitis C virus NS5B polymerase.
Hepatitis C
Binding-site identification and genotypic profiling of hepatitis C virus polymerase inhibitors.
Hepatitis C
Biochemical analyses of the interactions between viral polymerases and RNAs.
Hepatitis C
Biochemical and kinetic analyses of NS5B RNA-dependent RNA polymerase of the hepatitis C virus.
Hepatitis C
Biochemical and Pre-Steady-State Kinetic Characterization of the Hepatitis C Virus RNA Polymerase (NS5BDelta21, HC-J4).
Hepatitis C
Biochemical and structural analysis of the NS5B RNA-dependent RNA polymerase of the hepatitis C virus.
Hepatitis C
Biochemical characterization of a hepatitis C virus RNA-dependent RNA polymerase mutant lacking the C-terminal hydrophobic sequence.
Hepatitis C
Biochemical Characterization of the Active Anti-Hepatitis C Virus Metabolites of 2,6-Diaminopurine Ribonucleoside Prodrug Compared to Sofosbuvir and BMS-986094.
Hepatitis C
Biochemical properties of full-length hepatitis C virus RNA-dependent RNA polymerase expressed in insect cells.
Hepatitis C
Biochemical properties of hepatitis C virus NS5B RNA-dependent RNA polymerase and identification of amino acid sequence motifs essential for enzymatic activity.
Hepatitis C
Biochemical study of the comparative inhibition of hepatitis C virus RNA polymerase by VX-222 and filibuvir.
Hepatitis C
Bioengineered vaults: self-assembling protein shell-lipophilic core nanoparticles for drug delivery.
Hepatitis C
Biogenic polyamines spermine and spermidine activate RNA polymerase and inhibit RNA helicase of hepatitis C virus.
Hepatitis C
Biotransformation of Daclatasvir in Vitro and in Nonclinical Species: Formation of the Main Metabolite by Pyrrolidine ?-Oxidation and Rearrangement.
Hepatitis C
Blocking Zika virus vertical transmission.
Hepatitis C
Breaking self-tolerance toward cytochrome P4502E1 (CYP2E1) in chronic hepatitis C: possible role for molecular mimicry.
Hepatitis C
Broad-spectrum non-nucleoside inhibitors for caliciviruses.
Hepatitis C
Canonical 3'-deoxyribonucleotides as a chain terminator for HCV NS5B RNA-dependent RNA polymerase.
Hepatitis C
Cellular OCIAD2 protein is a proviral factor for hepatitis C virus replication.
Hepatitis C
Cellular RNA helicase p68 relocalization and interaction with the hepatitis C virus (HCV) NS5B protein and the potential role of p68 in HCV RNA replication.
Hepatitis C
Challenge to overcome: Nonstructural protein 5A-P32 deletion in direct-acting antiviral-based therapy for hepatitis C virus.
Hepatitis C
Changing the face of hepatitis C management - the design and development of sofosbuvir.
Hepatitis C
Chaperonin TRiC/CCT participates in replication of hepatitis C virus genome via interaction with the viral NS5B protein.
Hepatitis C
Characterization of a Threonine-Rich Cluster in Hepatitis C Virus Nonstructural Protein 5A and Its Contribution to Hyperphosphorylation.
Hepatitis C
Characterization of hepatitis C virus structural proteins with a recombinant baculovirus expression system.
Hepatitis C
Characterization of interactions between hepatitis C virus NS5B polymerase, annexin A2 and RNA - effects on NS5B catalysis and allosteric inhibition.
Hepatitis C
Characterization of monoclonal antibodies that specifically recognize the palm subdomain of hepatitis C virus nonstructural protein 5B polymerase.
Hepatitis C
Characterization of nonstructural protein membrane anchor deletion mutants expressed in the context of the hepatitis C virus polyprotein.
Hepatitis C
Characterization of Resistance to the Nonnucleoside NS5B Inhibitor Filibuvir in Hepatitis C Virus-Infected Patients.
Hepatitis C
Characterization of resistance to the protease inhibitor boceprevir in hepatitis C virus-infected patients.
Hepatitis C
Characterization of soluble hepatitis C virus RNA-dependent RNA polymerase expressed in Escherichia coli.
Hepatitis C
Characterization of the inhibition of hepatitis C virus RNA replication by nonnucleosides.
Hepatitis C
Characterization of the interaction between HCV NS5B and the human estrogen receptor alpha.
Hepatitis C
Characterization of the metabolic activation of hepatitis C virus nucleoside inhibitor beta-D-2'-Deoxy-2'-fluoro-2'-C-methylcytidine (PSI-6130) and identification of a novel active 5'-triphosphate species.
Hepatitis C
Characterization of the metal ion binding properties of the hepatitis C virus RNA polymerase.
Hepatitis C
Characterization of the nuclear localization signal and subcellular distribution of hepatitis C virus nonstructural protein NS5A.
Hepatitis C
Characterization of the RNA-binding domains in the replicase proteins of tomato bushy stunt virus.
Hepatitis C
Characterization of thiobarbituric acid derivatives as inhibitors of hepatitis C virus NS5B polymerase.
Hepatitis C
Characterizing ?-helical peptide aggregation on supported lipid membranes using microcantilevers.
Hepatitis C
Cholesterol-Enriched Domain Formation Induced by Viral-Encoded, Membrane-Active Amphipathic Peptide.
Hepatitis C
Chronic hepatitis E in a heart transplant patient: sofosbuvir and ribavirin regimen not fully effective.
Hepatitis C
Classification of HCV NS5B Polymerase Inhibitors Using Support Vector Machine.
Hepatitis C
Cleavage of hepatitis C virus nonstructural protein 5A by a caspase-like protease(s) in mammalian cells.
Hepatitis C
Cleavage of the hepatitis C virus NS5A protein by caspase-3 in the interferon sensitivity-determining region in a sequence-dependent manner.
Hepatitis C
Clinical and in vitro resistance to GS-9669, a thumb site II nonnucleoside inhibitor of the hepatitis C virus NS5B polymerase.
Hepatitis C
Clinical evaluation of efficacy, tolerability and pharmacokinetics of yimitasvir phosphate in patients infected with hepatitis C virus.
Hepatitis C
Clinical evaluation of three anti-HCV ELISAs in patients with various liver diseases.
Hepatitis C
Clinical evidence and bioinformatics characterization of potential hepatitis C virus resistance pathways for sofosbuvir.
Hepatitis C
Clinical Pharmacokinetics of Ombitasvir.
Hepatitis C
Clinical Resistance to Velpatasvir (GS-5816), a Novel Pan-Genotypic Inhibitor of the Hepatitis C Virus NS5A Protein.
Hepatitis C
Cochaperone activity of human butyrate-induced transcript 1 facilitates hepatitis C virus replication through an Hsp90-dependent pathway.
Hepatitis C
Combination therapies with NS5A, NS3 and NS5B inhibitors on different genotypes of hepatitis C virus in human hepatocyte chimeric mice.
Hepatitis C
Combinations of cyclophilin inhibitor NIM811 with hepatitis C Virus NS3-4A Protease or NS5B polymerase inhibitors enhance antiviral activity and suppress the emergence of resistance.
Hepatitis C
Combining 3-D quantitative structure-activity relationship with ligand based and structure based alignment procedures for in silico screening of new hepatitis C virus NS5B polymerase inhibitors.
Hepatitis C
Comparative mechanistic studies of de novo RNA synthesis by flavivirus RNA-dependent RNA polymerases.
Hepatitis C
Comparative molecular field analysis (CoMFA) and comparative molecular similarity indices analysis (CoMSIA) of thiazolone derivatives as hepatitis C virus NS5B polymerase allosteric inhibitors.
Hepatitis C
Compensatory mutations restore the replication defects caused by cytotoxic T lymphocyte escape mutations in hepatitis C virus polymerase.
Hepatitis C
Computational Analysis of De Novo Evolution of Hepatitis C Virus NS5B Polymerase Inhibitors.
Hepatitis C
Computational drug repurposing study elucidating simultaneous inhibition of entry and replication of novel corona virus by Grazoprevir.
Hepatitis C
Computational study on the drug resistance mechanism of HCV NS5B RNA-dependent RNA polymerase mutants V494I, V494A, M426A, and M423T to Filibuvir.
Hepatitis C
Concomitant proton pump inhibitor use does not reduce the efficacy of elbasvir/grazoprevir: A pooled analysis of 1,322 patients with hepatitis C infection.
Hepatitis C
Conformation-Based Restrictions and Scaffold Replacements in the Design of Hepatitis C Virus Polymerase Inhibitors: Discovery of Deleobuvir (BI 207127).
Hepatitis C
Conserved determinants for membrane association of nonstructural protein 5A from hepatitis C virus and related viruses.
Hepatitis C
Construction and characterization of Genotype-3 hepatitis C virus replicon revealed critical genotype-3-specific polymorphism for drug resistance and viral fitness.
Hepatitis C
Control of template positioning during de novo initiation of RNA synthesis by the bovine viral diarrhea virus NS5B polymerase.
Hepatitis C
Control of temporal activation of hepatitis C virus-induced interferon response by domain 2 of nonstructural protein 5A.
Hepatitis C
Coordination of Hepatitis C Virus Assembly by Distinct Regulatory Regions in Nonstructural Protein 5A.
Hepatitis C
Correction to Nucleoside, Nucleotide, and Non-Nucleoside Inhibitors of Hepatitis C Virus NS5B RNA-Dependent RNA-Polymerase.
Hepatitis C
Correction: Hepatitis C Virus Nonstructural Protein 5A Inhibits MG132-Induced Apoptosis of Hepatocytes in Line with NF-?B-Nuclear Translocation.
Hepatitis C
Cost-Effectiveness Analysis of Baseline Testing for Resistance-Associated Polymorphisms to Optimize Treatment Outcome in Genotype 1 Noncirrhotic Treatment-Naïve Patients With Chronic Hepatitis C Virus.
Hepatitis C
Cross-genotypic examination of hepatitis C virus polymerase inhibitors reveals a novel mechanism of action for thumb binders.
Hepatitis C
Crystal structure of the RNA polymerase domain of the West Nile virus non-structural protein 5.
Hepatitis C
Crystal structure of the RNA-dependent RNA polymerase from hepatitis C virus reveals a fully encircled active site.
Hepatitis C
Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virus.
Hepatitis C
Crystal structures of active and inactive conformations of a caliciviral RNA-dependent RNA polymerase.
Hepatitis C
Crystal structures of the RNA-dependent RNA polymerase genotype 2a of hepatitis C virus reveal two conformations and suggest mechanisms of inhibition by non-nucleoside inhibitors.
Hepatitis C
Crystallographic identification of a noncompetitive inhibitor binding site on the hepatitis C virus NS5B RNA polymerase enzyme.
Hepatitis C
Current and evolving therapies for hepatitis C.
Hepatitis C
Cyclophilin A allows the allosteric regulation of a structural motif in the disordered domain 2 of NS5A and thereby fine-tunes HCV RNA replication.
Hepatitis C
Cyclophilin B escorts the hepatitis C virus RNA polymerase: a viral achilles heel?
Hepatitis C
Cyclophilin B is a functional regulator of hepatitis C virus RNA polymerase.
Hepatitis C
Cyclophilin B stimulates RNA synthesis by the HCV RNA dependent RNA polymerase.
Hepatitis C
Cyclosporin A associated helicase-like protein facilitates the association of hepatitis C virus RNA polymerase with its cellular cyclophilin B.
Hepatitis C
Daclatasvir for the treatment of chronic hepatitis C virus infection.
Hepatitis C
Daclatasvir-like inhibitors of NS5A block early biogenesis of hepatitis C virus-induced membranous replication factories, independent of RNA replication.
Hepatitis C
De novo initiation of RNA synthesis by hepatitis C virus nonstructural protein 5B polymerase.
Hepatitis C
De novo initiation of RNA synthesis by the RNA-dependent RNA polymerase (NS5B) of hepatitis C virus.
Hepatitis C
De novo initiation pocket mutations have multiple effects on hepatitis C virus RNA-dependent RNA polymerase activities.
Hepatitis C
De novo RNA synthesis catalyzed by HCV RNA-dependent RNA polymerase.
Hepatitis C
Decentralized, Community-Based Hepatitis C Point-of-Care Testing and Direct-Acting Antiviral Treatment for People Who Inject Drugs and the General Population in Myanmar: Protocol for a Feasibility Study.
Hepatitis C
Defining the Role of Gut Bacteria in the Metabolism of Deleobuvir: In Vitro and In Vivo Studies.
Hepatitis C
Design and Construction of Aroyl-Hydrazone Derivatives: Synthesis, Crystal Structure, Molecular Docking and Their Biological Activities.
Hepatitis C
Design and evaluation of novel tetracyclic benzofurans as palm site allosteric inhibitors of HCV NS5B polymerase.
Hepatitis C
Design and synthesis of 2,3,4,9-tetrahydro-1H-carbazole and 1,2,3,4-tetrahydro-cyclopenta[b]indole derivatives as non-nucleoside inhibitors of hepatitis C virus NS5B RNA-dependent RNA polymerase.
Hepatitis C
Design and synthesis of L- and D-phenylalanine derived rhodanines with novel C5-arylidenes as inhibitors of HCV NS5B polymerase.
Hepatitis C
Design and synthesis of lactam-thiophene carboxylic acids as potent hepatitis C virus polymerase inhibitors.
Hepatitis C
Design and Synthesis of Novel Carbocyclic Versions of 2'-spirocyclopropyl Ribonucleosides as Potent Anti-HCV Agents.
Hepatitis C
Design, expression, and purification of a Flaviviridae polymerase using a high-throughput approach to facilitate crystal structure determination.
Hepatitis C
Design, synthesis and antiviral evaluation of 2'-C-methyl branched guanosine pronucleotides: the discovery of IDX184, a potent liver-targeted HCV polymerase inhibitor.
Hepatitis C
Design, synthesis, and antiviral activity of 2'-deoxy-2'-fluoro-2'-C-methylcytidine, a potent inhibitor of hepatitis C virus replication.
Hepatitis C
Design, synthesis, and structure-activity relationships of novel imidazo[4,5-c]pyridine derivatives as potent non-nucleoside inhibitors of hepatitis C virus NS5B.
Hepatitis C
Design, synthesis, assessment, and molecular docking of novel pyrrolopyrimidine (7-deazapurine) derivatives as non-nucleoside hepatitis C virus NS5B polymerase inhibitors.
Hepatitis C
Destabilization of PDK1 by Hsp90 inactivation suppresses hepatitis C virus replication through inhibition of PRK2-mediated viral RNA polymerase phosphorylation.
Hepatitis C
Detailed computational study of the active site of the hepatitis C viral RNA polymerase to aid novel drug design.
Hepatitis C
Detection of antigens related to hepatitis C virus RNA encoding the NS5 region in the livers of patients with chronic type C hepatitis.
Hepatitis C
Detection of hepatitis C virus NS5 protein and genome in Chinese carcinoma of the extrahepatic bile duct and its significance.
Hepatitis C
Detection of Hepatitis C Virus Quasispecies Heterogeneity by Single-Strand Conformational Polymorphism.
Hepatitis C
Detection of hepatitis C virus with RNA polymerase chain reaction in fulminant hepatic failure.
Hepatitis C
Detergent-induced activation of the hepatitis C virus genotype 1b RNA polymerase.
Hepatitis C
Determinants for membrane association of the hepatitis C virus RNA-dependent RNA polymerase.
Hepatitis C
Determination and control of TEMPO, a potentially genotoxic free radical reagent used in the synthesis of filibuvir.
Hepatitis C
Development and preliminary optimization of indole-N-acetamide inhibitors of hepatitis C virus NS5B polymerase.
Hepatitis C
Development of carboxylic acid replacements in indole-N-acetamide inhibitors of hepatitis C virus NS5B polymerase.
Hepatitis C
Development of intergenotypic chimeric replicons to determine the broad-spectrum antiviral activities of hepatitis C virus polymerase inhibitors.
Hepatitis C
Development of recombinant hepatitis C virus with NS5A from strains of genotypes 1 and 2.
Hepatitis C
Development of the system ensuring a high-level expression of hepatitis C virus nonstructural NS5B and NS5A proteins.
Hepatitis C
Different mechanisms of hepatitis C virus RNA polymerase activation by cyclophilin A and B in vitro.
Hepatitis C
Different Molecular Mechanisms of Inhibition of Bovine Viral Diarrhea Virus and Hepatitis C Virus RNA-Dependent RNA Polymerases by a Novel Benzimidazole.
Hepatitis C
Differential effect of interferon on hepatitis C virus 1b quasispecies in the nonstructural protein 5A gene.
Hepatitis C
Differential Proteomics Reveals Discrete Functions of Proteins Interacting with Hypo- versus Hyper-phosphorylated NS5A of the Hepatitis C Virus.
Hepatitis C
Difluoromethylornithine (DFMO), an Inhibitor of Polyamine Biosynthesis, and Antioxidant N-Acetylcysteine Potentiate Immune Response in Mice to the Recombinant Hepatitis C Virus NS5B Protein.
Hepatitis C
Dinucleotide analogues as novel inhibitors of RNA-dependent RNA polymerase of hepatitis C Virus.
Hepatitis C
Direct binding of a hepatitis C virus inhibitor to the viral capsid protein.
Hepatitis C
Direct detection of circulating hepatitis C virus RNA using probes from the 5' untranslated region.
Hepatitis C
Direct interaction between nucleolin and hepatitis C virus NS5B.
Hepatitis C
Discovery and Early Development of TMC647055, a Non-Nucleoside Inhibitor of the Hepatitis C Virus NS5B Polymerase.
Hepatitis C
Discovery and Preclinical Characterization of the Cyclopropylindolobenzazepine BMS-791325, A Potent Allosteric Inhibitor of the Hepatitis C Virus NS5B Polymerase.
Hepatitis C
Discovery and preclinical evaluation of potent, orally bioavailable, metabolically stable cyclopropylindolobenzazepine acylsulfonamides as thumb site 1 inhibitors of the hepatitis c virus NS5B RNA-dependent, RNA polymerase.
Hepatitis C
Discovery of (7R)-14-Cyclohexyl-7-{[2-(dimethylamino)ethyl](methyl) amino}-7,8-dihydro-6H-indolo[1,2-e][1,5]benzoxazocine-11-carboxylic Acid (MK-3281), a Potent and Orally Bioavailable Finger-Loop Inhibitor of the Hepatitis C Virus NS5B Polymerase.
Hepatitis C
Discovery of (R)-6-Cyclopentyl-6-(2-(2,6-diethylpyridin-4-yl)ethyl)-3-((5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)methyl)-4-hydroxy-5,6-dihydropyran-2-one (PF-00868554) as a Potent and Orally Available Hepatitis C Virus Polymerase Inhibitor.
Hepatitis C
Discovery of 4H-pyrazolo[1,5-a]pyrimidin-7-ones as potent inhibitors of hepatitis C virus polymerase.
Hepatitis C
Discovery of a Silicon-Containing Pan-Genotype Hepatitis C Virus NS5A Inhibitor.
Hepatitis C
Discovery of alpha,gamma-diketo acids as potent selective and reversible inhibitors of hepatitis C virus NS5b RNA-dependent RNA polymerase.
Hepatitis C
Discovery of benzophosphadiazine drug candidate IDX375: A novel hepatitis C allosteric NS5B RdRp inhibitor.
Hepatitis C
Discovery of BMS-961955, an allosteric inhibitor of the hepatitis C virus NS5B polymerase.
Hepatitis C
Discovery of conformationally constrained tetracyclic compounds as potent hepatitis C virus NS5B RNA polymerase inhibitors.
Hepatitis C
Discovery of hit molecules targeting allosteric site of hepatitis C virus NS5B polymerase.
Hepatitis C
Discovery of Metal Ions Chelator Quercetin Derivatives with Potent Anti-HCV Activities.
Hepatitis C
Discovery of N-[4-[6-tert-Butyl-5-methoxy-8-(6-methoxy-2-oxo-1H-pyridin-3-yl)-3-quinolyl]phenyl]methanesulfonamide (RG7109), a Potent Inhibitor of the Hepatitis C Virus NS5B Polymerase.
Hepatitis C
Discovery of Naturally Occurring Aurones That Are Potent Allosteric Inhibitors of Hepatitis C Virus RNA-Dependent RNA Polymerase.
Hepatitis C
Discovery of new scaffolds for rational design of HCV NS5B polymerase inhibitors.
Hepatitis C
Discovery of novel Hepatitis C virus inhibitor targeting multiple allosteric sites of NS5B polymerase.
Hepatitis C
Discovery of Novel Hepatitis C Virus NS5B Polymerase Inhibitors by Combining Random Forest, Multiple e-Pharmacophore Modeling and Docking.
Hepatitis C
Discovery of novel natural flavonoids as potent antiviral candidates against hepatitis C virus NS5B polymerase.
Hepatitis C
Discovery of Novel Thiophene-Based, Thumb Pocket 2 Allosteric Inhibitors of the Hepatitis C NS5B Polymerase with Improved Potency and Physicochemical Profiles.
Hepatitis C
Discovery of novel tricyclic indole derived inhibitors of HCV NS5B RNA dependent RNA polymerase.
Hepatitis C
Discovery of pentacyclic compounds as potent inhibitors of hepatitis C virus NS5B RNA polymerase.
Hepatitis C
Discovery of Potent Non-nucleoside Inhibitors of Dengue Viral RNA-Dependent RNA Polymerase from Fragment Screening and Structure-Guided Design.
Hepatitis C
Discovery of proline sulfonamides as potent and selective hepatitis C virus NS5b polymerase inhibitors. Evidence for a new NS5b polymerase binding site.
Hepatitis C
Discovery of SCH 900188: A Potent Hepatitis C Virus NS5B Polymerase Inhibitor Prodrug As a Development Candidate.
Hepatitis C
Discovery of substituted N-phenylbenzenesulphonamides as a novel class of non-nucleoside hepatitis C virus polymerase inhibitors.
Hepatitis C
Discovery of the First Thumb Pocket 1 NS5B Polymerase Inhibitor (BILB 1941) with Demonstrated Antiviral Activity in Patients Chronically Infected with Genotype 1 Hepatitis C Virus (HCV).
Hepatitis C
Distinct functions of NS5A in hepatitis C virus RNA replication uncovered by studies with the NS5A inhibitor BMS-790052.
Hepatitis C
Distribution of naturally -occurring NS5B resistance-associated substitutions in Egyptian patients with chronic Hepatitis C.
Hepatitis C
Docking ligands into flexible and solvated macromolecules. 2. Development and application of fitted 1.5 to the virtual screening of potential HCV polymerase inhibitors.
Hepatitis C
Domain 2 of nonstructural protein 5A (NS5A) of hepatitis C virus is natively unfolded.
Hepatitis C
Domain 3 of NS5A protein from the hepatitis C virus has intrinsic alpha-helical propensity and is a substrate of cyclophilin A.
Hepatitis C
Down-regulation of the retinoblastoma tumor suppressor by the hepatitis C virus NS5B RNA-dependent RNA polymerase.
Hepatitis C
Dual Allosteric Inhibitors Jointly Modulate Protein Structure and Dynamics in the Hepatitis C Virus Polymerase.
Hepatitis C
Dual therapy with the nonstructural protein 5A inhibitor, daclatasvir, and the nonstructural protein 3 protease inhibitor, asunaprevir, in hepatitis C virus genotype 1b-infected null responders.
Hepatitis C
Dynamics of HCV RNA-dependent RNA Polymerase NS5B in Complex with RNA.
Hepatitis C
Effect of Hepatitis C Virus (HCV) NS5B-Nucleolin Interaction on HCV Replication with HCV Subgenomic Replicon.
Hepatitis C
Effect of metal ion binding on the structural stability of the hepatitis C virus RNA polymerase.
Hepatitis C
Effect of mutation in the hepatitis C virus nonstructural 5B region on HCV replication.
Hepatitis C
Effect on Hepatitis C Virus Replication of Combinations of Direct-Acting Antivirals, Including NS5A Inhibitor Daclatasvir.
Hepatitis C
Effective epitope identification employing phylogenetic, mutational variability, sequence entropy, and correlated mutation analysis targeting NS5B protein of hepatitis C virus: from bioinformatics to therapeutics.
Hepatitis C
Effects of mutation in hepatitis C virus nonstructural protein 5A on interferon resistance mediated by inhibition of PKR kinase activity in mammalian cells.
Hepatitis C
Effects of mutations of the initiation nucleotides on hepatitis C virus RNA replication in the cell.
Hepatitis C
Efficacy and safety of a two-drug direct-acting antiviral agent regimen ruzasvir 180 mg and uprifosbuvir 450 mg for 12 weeks in adults with chronic hepatitis C virus genotype 1, 2, 3, 4, 5 or 6.
Hepatitis C
Efficacy and Safety of All-oral Emitasvir and Sofosbuvir in Patients with Genotype 1b HCV Infections without Cirrhosis.
Hepatitis C
Efficacy and safety of sofosbuvir-based therapy for the treatment of chronic hepatitis C in treatment-naïve and treatment-experienced patients.
Hepatitis C
Efficacy and safety of sofosbuvir-containing regimens in chronic hepatitis C patients with genotype 2 and 3: a comprehensive analysis of 18 randomized controlled trials.
Hepatitis C
Efficiency of incorporation and chain termination determines the inhibition potency of 2'-modified nucleotide analogs against hepatitis C virus polymerase.
Hepatitis C
Efficient In Silico Assay of Inhibitors of Hepatitis C Virus RNA-Dependent RNA Polymerase by Structure-Based Virtual Screening and In Vitro Evaluation.
Hepatitis C
Efficient rescue of hepatitis C virus RNA replication by trans-complementation with nonstructural protein 5A.
Hepatitis C
Elongation of synthetic RNA templates by hepatitis C virus NS5B polymerase.
Hepatitis C
Emergence of hepatitis C virus NS5A L31V plus Y93H variant upon treatment failure of daclatasvir and asunaprevir is relatively resistant to ledipasvir and NS5B polymerase nucleotide inhibitor GS-558093 in human hepatocyte chimeric mice.
Hepatitis C
Engineered retargeting of viral RNA replication complexes to an alternative intracellular membrane.
Hepatitis C
Enzymatic activities of the GB virus-B RNA-dependent RNA polymerase.
Hepatitis C
Enzymatic characterization of the full-length and C-terminally truncated hepatitis C virus RNA polymerases: function of the last 21 amino acids of the C terminus in template binding and RNA synthesis.
Hepatitis C
Essential role of domain III of nonstructural protein 5A for hepatitis C virus infectious particle assembly.
Hepatitis C
Establishment of stable HeLa cell lines expressing enzymatically active hepatitis C virus RNA polymerase.
Hepatitis C
Ethanol inhibition: the humoral and cellular immune response to hepatitis C virus NS5 protein after genetic immunization.
Hepatitis C
Etodolac Thiosemicarbazides: A novel class of hepatitis C virus NS5B polymerase inhibitors.
Hepatitis C
Evaluation of a prototype HCV NS5b assay for typing strains of hepatitis C virus isolated from Tunisian haemodialysis patients.
Hepatitis C
Evaluation of antiviral effects of novel NS5A inhibitors in hepatitis C virus cell culture system with full-genome infectious clones.
Hepatitis C
Evaluation of Coumarin and Neoflavone Derivatives as HCV NS5B Polymerase Inhibitors.
Hepatitis C
Evaluation of Inhibitory effects of Thiobarbituric Acid Derivatives Targeting HCV NS5B Polymerase.
Hepatitis C
Evaluation of methods for hepatitis C virus detection in archival liver biopsies. Comparison of histology, immunohistochemistry, in-situ hybridization, reverse transcriptase polymerase chain reaction (RT-PCR) and in-situ RT-PCR.
Hepatitis C
Evaluation of sofosbuvir activity and resistance profile against West Nile virus in vitro.
Hepatitis C
Evaluation of the effect of mericitabine at projected therapeutic and supratherapeutic doses on cardiac repolarization in healthy subjects: A thorough QT/QTc study.
Hepatitis C
Evidence for action of ribavirin through the hepatitis C virus RNA polymerase.
Hepatitis C
Evidence for Internal Initiation of RNA Synthesis by the Hepatitis C Virus RNA-Dependent RNA Polymerase NS5B In Cellulo.
Hepatitis C
Evolution of the NS3 and NS5B regions of the hepatitis C virus during disease recurrence after liver transplantation.
Hepatitis C
Expensiveness of hepatitis C virus polymerase inhibitor sofosbuvir: a warrant for therapeutic drug monitoring of compliance.
Hepatitis C
Expression and purification of untagged full-length HCV NS5B RNA-dependent RNA polymerase.
Hepatitis C
Expression of a hepatitis C virus NS3 protease-NS4A fusion protein in Escherichia coli.
Hepatitis C
Expression of hepatitis C virus NS5B protein: characterization of its RNA polymerase activity and RNA binding.
Hepatitis C
Finding new medicines for flaviviral targets.
Hepatitis C
First-in-Human Study of the Pharmacokinetics and Antiviral Activity of IDX375, a Novel Nonnucleoside Hepatitis C Virus Polymerase Inhibitor.
Hepatitis C
Fluorescence resonance energy transfer-based intracellular assay for the conformation of hepatitis C virus drug target NS5A.
Hepatitis C
Follow-up study of anti-hepatitis C virus antibodies in blood donors implicated in post-transfusion non-A, non-B hepatitis.
Hepatitis C
Forthcoming challenges in the management of STAT-C therapy.
Hepatitis C
Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors.
Hepatitis C
Functional analysis of RNA binding by the hepatitis C virus RNA-dependent RNA polymerase.
Hepatitis C
Functional characterization of fingers subdomain-specific monoclonal antibodies inhibiting the hepatitis C virus RNA-dependent RNA polymerase.
Hepatitis C
Functional properties of a monoclonal antibody inhibiting the hepatitis C virus RNA-dependent RNA polymerase.
Hepatitis C
Further insights into the roles of GTP and the C terminus of the hepatitis C virus polymerase in the initiation of RNA synthesis.
Hepatitis C
Further SAR studies on novel small molecule inhibitors of the hepatitis C (HCV) NS5B polymerase.
Hepatitis C
Further studies on hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitors toward improved replicon cell activities: benzimidazole and structurally related compounds bearing the 2-morpholinophenyl moiety.
Hepatitis C
General catalytic deficiency of hepatitis C virus RNA polymerase with an S282T mutation and mutually exclusive resistance towards 2'-modified nucleotide analogues.
Hepatitis C
Genetic and biochemical diversity in the HCV NS5B RNA polymerase in the context of interferon alpha plus ribavirin therapy.
Hepatitis C
Genetic complementation of hepatitis C virus nonstructural protein functions associated with replication exhibits requirements that differ from those for virion assembly.
Hepatitis C
Genetic diversity of the hepatitis C virus: impact and issues in the antiviral therapy.
Hepatitis C
Genomic-Scale Interaction Involving Complementary Sequences in the Hepatitis C Virus 5'UTR Domain IIa and the RNA-Dependent RNA Polymerase Coding Region Promotes Efficient Virus Replication.
Hepatitis C
Genotypic and phenotypic analyses of hepatitis C virus variants observed in clinical studies of VX-222, a nonnucleoside NS5B polymerase inhibitor.
Hepatitis C
Glecaprevir/Pibrentasvir in patients with hepatitis C virus genotype 1 or 4 and past direct-acting antiviral treatment failure.
Hepatitis C
GPS2 is required for the association of NS5A with VAP-A and hepatitis C virus replication.
Hepatitis C
GS-9857 in patients with chronic hepatitis C virus genotype 1-4 infection: a randomized, double-blind, dose-ranging phase 1 study.
Hepatitis C
HA1077 displays synergistic activity with daclatasvir against hepatitis C virus and suppresses the emergence of NS5A resistance-associated substitutions in mice.
Hepatitis C
HCV Genotype 6a Escape from and Resistance to Velpatasvir, Pibrentasvir, and Sofosbuvir in Robust Infectious Cell Culture Models.
Hepatitis C
HCV NS5A Inhibitors Modulate Multiple Aspects of NS5A Expression.
Hepatitis C
HCV796: A selective nonstructural protein 5B polymerase inhibitor with potent anti-hepatitis C virus activity in vitro, in mice with chimeric human livers, and in humans infected with hepatitis C virus.
Hepatitis C
Hemin potentiates the anti-hepatitis C virus activity of the antimalarial drug artemisinin.
Hepatitis C
Hepatitis C NS5B polymerase inhibitors: 4,4-Dialkyl-1-hydroxy-3-oxo-3,4-dihydronaphthalene-3-yl benzothiadiazine derivatives.
Hepatitis C
Hepatitis C NS5B polymerase inhibitors: Functional equivalents for the benzothiadiazine moiety.
Hepatitis C
Hepatitis C RNA-dependent RNA polymerase inhibitors: a review of structure-activity and resistance relationships; different scaffolds and mutations.
Hepatitis C
Hepatitis C therapy with HCV NS5B polymerase inhibitors.
Hepatitis C
Hepatitis C virus (HCV) NS2 protein up-regulates HCV IRES-dependent translation and down-regulates NS5B RdRp activity.
Hepatitis C
Hepatitis C virus (HCV) NS5A binds RNA-dependent RNA polymerase (RdRP) NS5B and modulates RNA-dependent RNA polymerase activity.
Hepatitis C
Hepatitis C virus co-opts Ras-GTPase-activating protein-binding protein 1 for its genome replication.
Hepatitis C
Hepatitis C virus core protein binds to a C-terminal region of NS5B RNA polymerase.
Hepatitis C
Hepatitis C Virus Genetic Variability and the Presence of NS5B Resistance-Associated Mutations as Natural Polymorphisms in Selected Genotypes Could Affect the Response to NS5B Inhibitors.
Hepatitis C
Hepatitis C virus genotypes and quasispecies.
Hepatitis C
Hepatitis C Virus in mainland China with an emphasis on genotype and subtype distribution.
Hepatitis C
Hepatitis C Virus Nonstructural 5A Protein (HCV-NS5A) Inhibits Hepatocyte Apoptosis through the NF-?b/miR-503/bcl-2 Pathway.
Hepatitis C
Hepatitis C virus nonstructural 5B protein regulates tumor necrosis factor alpha signaling through effects on cellular IkappaB kinase.
Hepatitis C
Hepatitis C virus nonstructural protein 5A (NS5A) is an RNA-binding protein.
Hepatitis C
Hepatitis C virus nonstructural protein 5A contains potential transcriptional activator domains.
Hepatitis C
Hepatitis C virus nonstructural protein 5A favors upregulation of gluconeogenic and lipogenic gene expression leading towards insulin resistance: a metabolic syndrome.
Hepatitis C
Hepatitis C virus nonstructural protein 5A inhibitors: novel target-now for new trials and new treatment strategies.
Hepatitis C
Hepatitis C Virus Nonstructural Protein 5A Inhibits MG132-Induced Apoptosis of Hepatocytes in Line with NF-?B-Nuclear Translocation.
Hepatitis C
Hepatitis C virus nonstructural protein 5A inhibits thapsigargin-induced apoptosis.
Hepatitis C
Hepatitis C virus nonstructural protein 5A inhibits tumor necrosis factor-alpha-mediated apoptosis in Huh7 cells.
Hepatitis C
Hepatitis C virus nonstructural protein 5A modulates the toll-like receptor-MyD88-dependent signaling pathway in macrophage cell lines.
Hepatitis C
Hepatitis C virus nonstructural protein 5A perturbs lipid metabolism by modulating AMPK/SREBP-1c signaling.
Hepatitis C
Hepatitis C virus nonstructural protein NS(3) and telomerase activity.
Hepatitis C
Hepatitis C virus nonstructural protein NS4B transforms NIH3T3 cells in cooperation with the Ha-ras oncogene.
Hepatitis C
Hepatitis C virus nonstructural protein specific T cells are associated with virological responses to combination therapy in chronic HCV patients.
Hepatitis C
Hepatitis C virus NS2/3 protease regulates HCV IRES-dependent translation and NS5B RdRp activity.
Hepatitis C
Hepatitis C virus NS5A and subgenomic replicon activate NF-kappaB via tyrosine phosphorylation of IkappaBalpha and its degradation by calpain protease.
Hepatitis C
Hepatitis C virus NS5A colocalizes with the core protein on lipid droplets and interacts with apolipoproteins.
Hepatitis C
Hepatitis C virus NS5A promotes insulin resistance through IRS-1 serine phosphorylation and increased gluconeogenesis.
Hepatitis C
Hepatitis C virus NS5A protein modulates template selection by the RNA polymerase in in vitro system.
Hepatitis C
Hepatitis C virus NS5B and host cyclophilin A share a common binding site on NS5A.
Hepatitis C
Hepatitis C virus NS5B polymerase exhibits distinct nucleotide requirements for initiation and elongation.
Hepatitis C
Hepatitis C virus NS5B polymerase primes innate immune signaling.
Hepatitis C
Hepatitis C virus NS5B polymerase: QM/MM calculations show the important role of the internal energy in ligand binding.
Hepatitis C
Hepatitis C Virus NS5B Protein Delays S Phase Progression in Human Hepatocyte-derived Cells by Relocalizing Cyclin-dependent Kinase 2-interacting Protein (CINP).
Hepatitis C
Hepatitis C virus NS5B protein is a membrane-associated phosphoprotein with a predominantly perinuclear localization.
Hepatitis C
Hepatitis C virus NS5B RNA replicase specifically binds ribosomes.
Hepatitis C
Hepatitis C Virus Particle Assembly Involves Phosphorylation of NS5A by the c-Abl Tyrosine Kinase.
Hepatitis C
Hepatitis C virus quasispecies variability modulates nonstructural protein 5A transcriptional activation, pointing to cellular compartmentalization of virus-host interactions.
Hepatitis C
Hepatitis C virus replication is modulated by the interaction of non-structural protein NS5B and fatty acid synthase.
Hepatitis C
Hepatitis C Virus RNA Elimination and Development of Resistance in Replicon Cells Treated with BMS-790052.
Hepatitis C
Hepatitis C virus RNA polymerase and NS5A complex with a SNARE-like protein.
Hepatitis C
Hepatitis C virus RNA replication is regulated by FKBP8 and Hsp90.
Hepatitis C
Hepatitis C virus RNA replication requires a conserved structural motif within the transmembrane domain of the NS5B RNA-dependent RNA polymerase.
Hepatitis C
Hepatitis C virus RNA synthesis in a cell-free system isolated from replicon-containing hepatoma cells.
Hepatitis C
Hepatitis C virus RNA-dependent RNA polymerase (NS5B polymerase).
Hepatitis C
Hepatitis C Virus RNA-Dependent RNA Polymerase (NS5B Polymerase).
Hepatitis C
Hepatitis C virus RNA-dependent RNA polymerase (NS5B) as a mediator of the antiviral activity of ribavirin.
Hepatitis C
Hepatitis C Virus RNA-Dependent RNA Polymerase Is Regulated by Cysteine S-Glutathionylation.
Hepatitis C
Hepatitis C virus RNA-dependent RNA polymerase: study on the inhibition mechanism by pyrogallol derivatives.
Hepatitis C
Hepatitis C Virus Subverts Human Choline Kinase-? To Bridge Phosphatidylinositol-4-Kinase III? (PI4KIII?) and NS5A and Upregulates PI4KIII? Activation, Thereby Promoting the Translocation of the Ternary Complex to the Endoplasmic Reticulum for Viral Replication.
Hepatitis C
Hepatitis C virus-cross-reactive TCR gene-modified T cells: a model for immunotherapy against diseases with genomic instability.
Hepatitis C
Hepatitis C virus-encoded nonstructural protein NS4A has versatile functions in viral protein processing.
Hepatitis C
Hepatitis G virus infection in patients with hepatocellular carcinoma in Recife, Brazil.
Hepatitis C
Hepatitis C virus nonstructural 5A protein inhibits the starvation?induced apoptosis of hepatoblastoma cells by increasing Beclin 1 expression.
Hepatitis C
Heterogeneity within the nonstructural protein 5-encoding region of hepatitis C viruses from a single patient.
Hepatitis C
Heterologous RNA replication enhancer stimulates in vitro RNA synthesis and template-switching by the carmovirus, but not by the tombusvirus, RNA-dependent RNA polymerase: implication for modular evolution of RNA viruses.
Hepatitis C
High resolution footprinting of the hepatitis C virus polymerase NS5B in complex with RNA.
Hepatitis C
High-affinity aptamers to subtype 3a hepatitis C virus polymerase display genotypic specificity.
Hepatitis C
Human butyrate-induced transcript 1 interacts with hepatitis C virus NS5A and regulates viral replication.
Hepatitis C
Human eukaryotic initiation factor 4AII associates with hepatitis C virus NS5B protein in vitro.
Hepatitis C
Human hepatitis C virus NS5A protein alters intracellular calcium levels, induces oxidative stress, and activates STAT-3 and NF-kappa B.
Hepatitis C
Human Immunodeficiency Virus Viral Load Rebound Near Delivery in Previously Suppressed, Combination Antiretroviral Therapy-Treated Pregnant Women.
Hepatitis C
Human immunodeficiency virus-reverse transcriptase inhibition and hepatitis C virus RNA-dependent RNA polymerase inhibition activities of fullerene derivatives.
Hepatitis C
Human VAP-B is involved in hepatitis C virus replication through interaction with NS5A and NS5B.
Hepatitis C
Hydrogen/Deuterium Exchange Kinetics Demonstrate Long Range Allosteric Effects of Thumb Site 2 Inhibitors of Hepatitis C Viral RNA-dependent RNA Polymerase.
Hepatitis C
Hydrophobic and Charged Residues in the C-Terminal Arm of Hepatitis C Virus RNA-Dependent RNA Polymerase Regulate Initiation and Elongation.
Hepatitis C
Hyperphosphorylation of the hepatitis C virus NS5A protein requires an active NS3 protease, NS4A, NS4B, and NS5A encoded on the same polyprotein.
Hepatitis C
Identification and Analysis of Novel Inhibitors against NS3 Helicase and NS5B RNA-Dependent RNA Polymerase from Hepatitis C Virus 1b (Con1).
Hepatitis C
Identification and biological characterization of heterocyclic inhibitors of the hepatitis C virus RNA-dependent RNA polymerase.
Hepatitis C
Identification and Biological Evaluation of a Series of 1H-Benzo[de]isoquinoline-1,3(2H)-diones as Hepatitis C Virus NS5B Polymerase Inhibitors (double dagger).
Hepatitis C
Identification and functional characterization of the nascent RNA contacting residues of the hepatitis C virus RNA-dependent RNA polymerase.
Hepatitis C
Identification and properties of the RNA-dependent RNA polymerase of hepatitis C virus.
Hepatitis C
Identification of a C-terminal regulatory motif in hepatitis C virus RNA-dependent RNA polymerase: structural and biochemical analysis.
Hepatitis C
Identification of a novel resistance mutation for benzimidazole inhibitors of the HCV RNA-dependent RNA polymerase.
Hepatitis C
Identification of a ribavirin-resistant NS5B mutation of hepatitis C virus during ribavirin monotherapy.
Hepatitis C
Identification of a structural element of the hepatitis C virus minus strand RNA involved in the initiation of RNA synthesis.
Hepatitis C
Identification of allosteric inhibitors blocking the hepatitis C virus polymerase NS5B in the RNA synthesis initiation step.
Hepatitis C
Identification of anthranilic acid derivatives as a novel class of allosteric inhibitors of hepatitis C NS5B polymerase.
Hepatitis C
Identification of Anthranilic Acid Derivatives as a Novel Class of Allosteric Inhibitors of Hepatitis C NS5B Polymerase.
Hepatitis C
Identification of B cell epitopes of hepatitis C virus RNA dependent RNA polymerase.
Hepatitis C
Identification of constrained peptides that bind to and preferentially inhibit the activity of the hepatitis C viral RNA-dependent RNA polymerase.
Hepatitis C
Identification of N,N-disubstituted phenylalanines as a novel class of inhibitors of hepatitis C NS5B polymerase.
Hepatitis C
Identification of novel HCV RNA-dependent RNA polymerase inhibitors using pharmacophore-guided virtual screening.
Hepatitis C
Identification of potential anti-hepatitis C virus agents targeting non structural protein 5B using computational techniques.
Hepatitis C
Identification of potential inhibitors for HCV NS5b of genotype 4a by combining dynamic simulation, protein-ligand interaction fingerprint, 3D pharmacophore, docking and 3D QSAR.
Hepatitis C
Identification of RNA ligands that bind hepatitis C virus polymerase selectively and inhibit its RNA synthesis from the natural viral RNA templates.
Hepatitis C
Identification of small molecule inhibitors of the hepatitis C virus RNA-dependent RNA polymerase from a pyrrolidine combinatorial mixture.
Hepatitis C
Identification of the sequence on NS4A required for enhanced cleavage of the NS5A/5B site by hepatitis C virus NS3 protease.
Hepatitis C
Identification of thieno[3,2-b]pyrroles as allosteric inhibitors of hepatitis C virus NS5B polymerase.
Hepatitis C
Identification of two flavivirus-like genomes in the GB hepatitis agent.
Hepatitis C
IDX-184 is a superior HCV direct-acting antiviral drug: a QSAR study.
Hepatitis C
Imidazopyridazine hepatitis C virus polymerase inhibitors. Structure-activity relationship studies and the discovery of a novel, traceless prodrug mechanism.
Hepatitis C
Immune response to a hepatitis C virus nonstructural protein in chronic hepatitis C virus infection.
Hepatitis C
Impact of antiretroviral therapy on the variability of the HCV NS5B polymerase in HIV/HCV co-infected patients.
Hepatitis C
Improved replicon cellular activity of non-nucleoside allosteric inhibitors of HCV NS5B polymerase: From benzimidazole to indole scaffolds.
Hepatitis C
Improved serodiagnosis of non-A, non-B hepatitis by an assay detecting antibody to hepatitis C virus core antigen.
Hepatitis C
Improvement of hepatitis C virus RNA polymerase chain reaction through a multicentre quality control study. French Study Group for the Standardization of Hepatitis C Virus PCR.
Hepatitis C
Improving Metabolic Stability with Deuterium: The Discovery of BMT-052, a Pan-genotypic HCV NS5B Polymerase Inhibitor.
Hepatitis C
In Silico Approaches to the Design of NS5A Inhibitors.
Hepatitis C
In silico prediction of SARS-CoV-2 main protease and polymerase inhibitors: 3D-Pharmacophore modelling.
Hepatitis C
In situ enzymatic oligonucleotide amplification of hepatitis C virus-RNA in liver biopsy specimens (reverse transcriptase in situ polymerase chain reaction) after orthotopic liver transplantation for hepatitis C-related liver disease.
Hepatitis C
In vitro activity and resistance profile of dasabuvir, a nonnucleoside hepatitis C virus polymerase inhibitor.
Hepatitis C
In Vitro Activity of BMS-790052 on Hepatitis C Virus Genotype 4 NS5A.
Hepatitis C
In vitro resistance study of AG-021541, a novel nonnucleoside inhibitor of the hepatitis C virus RNA-dependent RNA polymerase.
Hepatitis C
In vitro selection of RNA aptamers that bind the RNA-dependent RNA polymerase of hepatitis C virus: a possible role of GC-rich RNA motifs in NS5B binding.
Hepatitis C
In vitro selection of the 3'-untranslated regions of the human liver mRNA that bind to the HCV nonstructural protein 5B.
Hepatitis C
Inducible CYP4F12 enhances Hepatitis C virus infection via association with viral nonstructural protein 5B.
Hepatitis C
Infrequent development of resistance in genotype 1-6 hepatitis C virus-infected subjects treated with sofosbuvir in phase 2 and 3 clinical trials.
Hepatitis C
Inhibition of dengue virus polymerase by blocking of the RNA tunnel.
Hepatitis C
Inhibition of expression of rna polymerase with small interfering RNAs targeting a conserved motif in the respective viral genes in viruses of the family Flaviviridae.
Hepatitis C
Inhibition of hepatitis C viral RNA-dependent RNA polymerase by ?-P-boranophosphate nucleotides: Exploring a potential strategy for mechanism-based HCV drug design.
Hepatitis C
Inhibition of hepatitis C virus (HCV) replication by specific RNA aptamers against HCV NS5B RNA replicase.
Hepatitis C
Inhibition of hepatitis C virus (HCV) RNA polymerase by DNA aptamers: mechanism of inhibition of in vitro RNA synthesis and effect on HCV-infected cells.
Hepatitis C
Inhibition of hepatitis C virus nonstructural protein, helicase activity, and viral replication by a recombinant human antibody clone.
Hepatitis C
Inhibition of hepatitis C virus NS5B polymerase by S-trityl-l-cysteine derivatives.
Hepatitis C
Inhibition of Hepatitis C Virus Replication by GS-6620, a Potent C-Nucleoside Monophosphate Prodrug.
Hepatitis C
Inhibition of hepatitis C virus replication by Monascus pigment derivatives that interfere with viral RNA polymerase activity and the mevalonate biosynthesis pathway.
Hepatitis C
Inhibition of hepatitis C virus RNA replication by 2'-modified nucleoside analogs.
Hepatitis C
Inhibition of intrahepatic gamma interferon production by hepatitis C virus nonstructural protein 5A in transgenic mice.
Hepatitis C
Inhibition of RNA binding to hepatitis C virus RNA-dependent RNA polymerase: a new mechanism for antiviral intervention.
Hepatitis C
Inhibition of the subgenomic hepatitis C virus replicon in huh-7 cells by 2'-deoxy-2'-fluorocytidine.
Hepatitis C
Inhibitors for the hepatitis C virus RNA polymerase explored by SAR with advanced machine learning methods.
Hepatitis C
Inhibitors of hepatitis C virus polymerase: synthesis and biological characterization of unsymmetrical dialkyl-hydroxynaphthalenoyl-benzothiadiazines.
Hepatitis C
Inhibitors of hepatitis C virus polymerase: synthesis and characterization of novel 2-oxy-6-fluoro-N-((S)-1-hydroxy-3-phenylpropan-2-yl)-benzamides.
Hepatitis C
Inhibitors of the HCV NS5B polymerase: new hope for the treatment of hepatitis C infections.
Hepatitis C
Inhibitors of the Hepatitis C Virus Polymerase; Mode of Action and Resistance.
Hepatitis C
Inhibitors of the Hepatitis C Virus RNA-Dependent RNA Polymerase NS5B.
Hepatitis C
Initial binding of the broad spectrum antiviral nucleoside ribavirin to the hepatitis C virus RNA polymerase.
Hepatitis C
Initial results of efficacy and safety of Sofosbuvir among Pakistani Population: A real life trial - Hepatitis Eradication Accuracy Trial of Sofosbuvir (HEATS).
Hepatitis C
Initiation of RNA synthesis by the hepatitis C virus RNA-dependent RNA polymerase is affected by the structure of the RNA template.
Hepatitis C
Insertion of green fluorescent protein into nonstructural protein 5A allows direct visualization of functional hepatitis C virus replication complexes.
Hepatitis C
Insight into the drug resistance mechanisms of GS-9669 caused by mutations of HCV NS5B polymerase via molecular simulation.
Hepatitis C
Insight into the Structural Requirements of Benzothiadiazine Scaffold-Based Derivatives as Hepatitis C Virus NS5B Polymerase Inhibitors Using 3D-QSAR, Molecular Docking and Molecular Dynamics.
Hepatitis C
Insights into structural dynamics of allosteric binding sites in HCV RNA-dependent RNA polymerase.
Hepatitis C
Interaction of hepatitis C virus nonstructural protein 5A with core protein is critical for the production of infectious virus particles.
Hepatitis C
Interaction of hepatitis C virus NS5A with La protein revealed by T7 phage display.
Hepatitis C
Interaction of Nonstructural Protein 5A of the Hepatitis C Virus with Src Homology 3 Domains Using Noncanonical Binding Sites.
Hepatitis C
Interaction of stomatin with hepatitis C virus RNA polymerase stabilizes the viral RNA replicase complexes on detergent-resistant membranes.
Hepatitis C
Interaction of the hepatitis B virus X protein with the lysine methyltransferase SET and MYND domain-containing 3 induces activator protein 1 activation.
Hepatitis C
Interaction study between HCV NS5A-D2 and NS5B using
Hepatitis C
Interaction with a ubiquitin-like protein enhances the ubiquitination and degradation of hepatitis C virus RNA-dependent RNA polymerase.
Hepatitis C
Interactions between Viperin, Vesicle-Associated Membrane Protein A, and Hepatitis C Virus Protein NS5A Modulate Viperin Activity and NS5A Degradation.
Hepatitis C
Interactions of the Disordered Domain II of Hepatitis C Virus NS5A with Cyclophilin A, NS5B, and Viral RNA Show Extensive Overlap.
Hepatitis C
Interdomain communication in hepatitis C virus polymerase abolished by small molecule inhibitors bound to a novel allosteric site.
Hepatitis C
Interference of hepatitis C virus replication in cell culture by antisense peptide nucleic acids targeting the X-RNA.
Hepatitis C
Interferon and ribavirin therapy does not select for resistance mutations in hepatitis C virus polymerase.
Hepatitis C
Internal initiation sites of de novo RNA synthesis within the hepatitis C virus polypyrimidine tract.
Hepatitis C
Intracellular Effects of the Hepatitis C Virus Nucleoside Polymerase Inhibitor RO5855 (Mericitabine Parent) and Ribavirin in Combination.
Hepatitis C
Intracellular hepatitis C virus RNA-dependent RNA polymerase activity.
Hepatitis C
Investigation of Interferon-? Response by a Single Amino Acid Substitution of Nonstructural Protein 5A in Hepatitis C Virus-Infected Patients.
Hepatitis C
Investigation of the mode of binding of a novel series of N-benzyl-4-heteroaryl-1-(phenylsulfonyl)piperazine-2-carboxamides to the hepatitis C virus polymerase.
Hepatitis C
Investigation of translocation, DNA unwinding, and protein displacement by NS3h, the helicase domain from the hepatitis C virus helicase.
Hepatitis C
Involvement of hepatitis C virus NS5A hyperphosphorylation mediated by casein kinase I-? in infectious virus production.
Hepatitis C
In vitro antiviral activities of extracts derived from Daucus maritimus seeds.
Hepatitis C
Iron inactivates the RNA polymerase NS5B and suppresses subgenomic replication of hepatitis C Virus.
Hepatitis C
Is investigation of hepatitis C virus NS5A gene heterogeneity a tool for predicting long-lasting response to interferon therapy in patients with HCV-1b chronic hepatitis?
Hepatitis C
JTK-853, a Novel Non-Nucleoside Hepatitis C Virus Polymerase Inhibitor, Demonstrates a High Genetic Barrier to Resistance in vitro.
Hepatitis C
Kinetic analysis of C-terminally truncated RNA-dependent RNA polymerase of hepatitis C virus.
Hepatitis C
Kinetic profile of a heterocyclic HCV replicon RNA synthesis inhibitor.
Hepatitis C
Lack of mother-to-infant transmission of hepatitis C virus in human immunodeficiency virus-seronegative women: a prospective study with hepatitis C virus RNA testing.
Hepatitis C
Large-scale structure-activity relationship study of hepatitis C virus NS5B polymerase inhibition using SMILES-based descriptors.
Hepatitis C
Ledipasvir/Sofosbuvir: a review of its use in chronic hepatitis C.
Hepatitis C
Ligand and structure based virtual screening strategies for hit-finding and optimization of hepatitis C virus (HCV) inhibitors.
Hepatitis C
Ligand-induced changes in hepatitis C virus NS5B polymerase structure.
Hepatitis C
Lipid droplet-binding protein TIP47 regulates hepatitis C Virus RNA replication through interaction with the viral NS5A protein.
Hepatitis C
Liver histology in anti-HCV-positive persons with normal or minimally elevated aminotransferases.
Hepatitis C
Liver-targeted prodrugs of 2'-C-methyladenosine for therapy of hepatitis C virus infection.
Hepatitis C
Localization determines function: N-terminally truncated NS5A fragments accumulate in the nucleus and impair HCV replication.
Hepatitis C
Logical design of anti-prion agents using NAGARA.
Hepatitis C
Low susceptibility of asunaprevir towards R155K and D168A point mutations in HCV NS3/4A protease: A molecular dynamics simulation.
Hepatitis C
Mapping cooperative activity of the hepatitis C virus RNA-dependent RNA polymerase using genotype 1a-1b chimeras.
Hepatitis C
Mass balance, metabolite profile, and in vitro-in vivo comparison of clearance pathways of deleobuvir, a hepatitis C virus polymerase inhibitor.
Hepatitis C
MAVS-mediated apoptosis and its inhibition by viral proteins.
Hepatitis C
Mean protein evolutionary distance: a method for comparative protein evolution and its application.
Hepatitis C
Measurement of HCV RdRp activity with C-terminal 21 aa truncated NS5b protein: optimization of assay conditions.
Hepatitis C
Mechanism of action and antiviral activity of benzimidazole-based allosteric inhibitors of the hepatitis C virus RNA-dependent RNA polymerase.
Hepatitis C
Mechanism of activation of beta-D-2'-deoxy-2'-fluoro-2'-c-methylcytidine and inhibition of hepatitis C virus NS5B RNA polymerase.
Hepatitis C
Mechanism of an amphipathic alpha-helical peptide's antiviral activity involves size-dependent virus particle lysis.
Hepatitis C
Mechanism of de novo initiation by the hepatitis C virus RNA-dependent RNA polymerase: role of divalent metals.
Hepatitis C
Mechanism of hepatitis C virus RNA polymerase inhibition with dihydroxypyrimidines.
Hepatitis C
Mechanism of inhibition for BMS-791325, a novel non-nucleoside inhibitor of hepatitis C virus NS5B polymerase.
Hepatitis C
Mechanisms of activity and inhibition of the hepatitis C virus RNA-dependent RNA polymerase.
Hepatitis C
Mechanistic Characterization of GS-9190 (Tegobuvir), a Novel Nonnucleoside Inhibitor of Hepatitis C Virus NS5B Polymerase.
Hepatitis C
Mechanistic insight on the remdesivir binding to RNA-Dependent RNA polymerase (RdRp) of SARS-cov-2.
Hepatitis C
Mechanistic study of HCV polymerase inhibitors at individual steps of the polymerization reaction.
Hepatitis C
Medicinal chemistry of anthranilic acid derivatives: A mini review.
Hepatitis C
Membrane association of the RNA-dependent RNA polymerase is essential for hepatitis C virus RNA replication.
Hepatitis C
Metabolism and Disposition of Pan-Genotypic Inhibitor of Hepatitis C Virus NS5A Ombitasvir in Humans.
Hepatitis C
Microbead-based affinity chromatography chip using RNA aptamer modified with photocleavable linker.
Hepatitis C
Miniaturization of a hepatitis C virus RNA polymerase assay using a -102 degrees C cooled CCD camera-based imaging system.
Hepatitis C
Modification of hepatitis C virus 1b RNA polymerase to make a highly active JFH1-type polymerase by mutation of the thumb domain.
Hepatitis C
Modular Combination of Proteolysis-Responsive Transcription and Spherical Nucleic Acids for Smartphone-Based Colorimetric Detection of Protease Biomarkers.
Hepatitis C
Modulation of cell growth by the hepatitis C virus nonstructural protein NS5A.
Hepatitis C
Modulation of hepatitis C virus RNA-dependent RNA polymerase activity by structure-based site-directed mutagenesis.
Hepatitis C
Modulation of the hepatitis C virus RNA-dependent RNA polymerase activity by the non-structural (NS) 3 helicase and the NS4B membrane protein.
Hepatitis C
Modulation of vaccine-induced immune responses to hepatitis C virus in rhesus macaques by altering priming before adenovirus boosting.
Hepatitis C
Molecular and structural basis for the roles of hepatitis C virus polymerase NS5B amino acids 15, 223, and 321 in viral replication and drug resistance.
Hepatitis C
Molecular design, synthesis and cell based HCV replicon assay of novel benzoxazole derivatives.
Hepatitis C
Molecular docking revealed the binding of nucleotide/side inhibitors to Zika viral polymerase solved structures.
Hepatitis C
Molecular mechanism of a thumb domain hepatitis C virus nonnucleoside RNA-dependent RNA polymerase inhibitor.
Hepatitis C
Molecular mechanism of hepatitis C virus replicon variants with reduced susceptibility to a benzofuran inhibitor, HCV-796.
Hepatitis C
Molecular model of SARS coronavirus polymerase: implications for biochemical functions and drug design.
Hepatitis C
Molecular modeling and residue interaction network studies on the mechanism of binding and resistance of the HCV NS5B polymerase mutants to VX-222 and ANA598.
Hepatitis C
Molecular Neuroprotection Induced by Zinc-Dependent Expression of Hepatitis C-Derived Protein NS5A Targeting Kv2.1 Potassium Channels.
Hepatitis C
Molecular simulations illuminate the role of regulatory components of the RNA polymerase from the hepatitis C virus in influencing protein structure and dynamics.
Hepatitis C
Monitoring hepatitis C virus (HCV) RNA-dependent RNA polymerase oligomerization by a FRET-based in vitro system.
Hepatitis C
Monoclonal antibody recognizing N-terminal epitope of hepatitis C virus nonstructural 5B inhibits viral RNA replication.
Hepatitis C
Multiple e-pharmacophore modeling, 3D-QSAR, and high-throughput virtual screening of hepatitis C virus NS5B polymerase inhibitors.
Hepatitis C
Multiple interactions within the hepatitis C virus RNA polymerase repress primer-dependent RNA synthesis.
Hepatitis C
Multiple ligand detection and affinity measurement by ultrafiltration and mass spectrometry analysis applied to fragment mixture screening.
Hepatitis C
Multiple virtual screening approaches for finding new hepatitis C virus RNA-dependent RNA polymerase inhibitors: structure-based screens and molecular dynamics for the pursue of new poly pharmacological inhibitors.
Hepatitis C
Mutagenesis analysis of the rGTP-specific binding site of hepatitis C virus RNA-dependent RNA polymerase.
Hepatitis C
Mutagenic and inhibitory effects of ribavirin on hepatitis C virus RNA polymerase.
Hepatitis C
Mutational analysis of hepatitis C virus nonstructural protein 5A: potential role of differential phosphorylation in RNA replication and identification of a genetically flexible domain.
Hepatitis C
Mutational Analysis of Hepatitis C Virus NS5B in the Subgenomic Replicon Cell Culture.
Hepatitis C
Mutational analysis of the structure and functions of hepatitis C virus RNA-dependent RNA polymerase.
Hepatitis C
Mutations conferring resistance to a hepatitis C virus (HCV) RNA-dependent RNA polymerase inhibitor alone or in combination with an HCV serine protease inhibitor in vitro.
Hepatitis C
Mutations in nonstructural protein 5A gene and response to interferon in hepatitis C virus genotype 2 infection.
Hepatitis C
Mutations in NS5A region of hepatitis C virus genome correlate with presence of NS5A antibodies and response to interferon therapy for most common European hepatitis C virus genotypes.
Hepatitis C
Mutations in NS5B polymerase of hepatitis C virus: impacts on in vitro enzymatic activity and viral RNA replication in the subgenomic replicon cell culture.
Hepatitis C
Mutations in the hepatitis C virus polymerase that increase RNA binding can confer resistance to cyclosporine A.
Hepatitis C
Mutations in the nonstructural 5A region of hepatitis C virus and response of chronic hepatitis C to interferon alfa.
Hepatitis C
Mutations in the nonstructural protein 5A gene and response to interferon in patients with chronic hepatitis C virus 1b infection.
Hepatitis C
Mutations in the nonstructural protein 5A gene and response to interferon therapy in young patients with chronic hepatitis C virus 1b infection.
Hepatitis C
Mutations in the nonstructural region 5B of hepatitis C virus genotype 1b: their relation to viral load, response to interferon, and the nonstructural region 5A.
Hepatitis C
Mutations in the NS5A region do not predict interferon-responsiveness in american patients infected with genotype 1b hepatitis C virus.
Hepatitis C
N-Acetamideindolecarboxylic acid allosteric 'finger-loop' inhibitors of the hepatitis C virus NS5B polymerase: discovery and initial optimization studies.
Hepatitis C
Nanofiltration of single plasma donations: feasibility study.
Hepatitis C
Natural variation in drug susceptibility to HCV polymerase inhibitors in treatment-naïve HCV patient isolates.
Hepatitis C
Naturally occurring dominant drug resistance mutations occur infrequently in the setting of recently acquired hepatitis C.
Hepatitis C
Naturally occurring mutations in the nonstructural region 5B of hepatitis C virus (HCV) from treatment-naïve Korean patients chronically infected with HCV genotype 1b.
Hepatitis C
Naturally occurring substitutions conferring resistance to hepatitis C virus polymerase inhibitors in treatment-naive patients infected with genotypes 1-5.
Hepatitis C
New horizons in Hepatitis C antiviral therapy with direct-acting antivirals.
Hepatitis C
New Non-nucleoside Inhibitors of Hepatitis C Virus RNA-Dependent RNA Polymerase.
Hepatitis C
New NS5B polymerase inhibitors for hepatitis C.
Hepatitis C
New pseudodimeric aurones as palm pocket inhibitors of Hepatitis C virus RNA-dependent RNA polymerase.
Hepatitis C
New Pyrazolobenzothiazine Derivatives as Hepatitis C Virus NS5B Polymerase Palm Site I Inhibitors.
Hepatitis C
NMR reveals the intrinsically disordered domain 2 of NS5A protein as an allosteric regulator of the hepatitis C virus RNA polymerase NS5B.
Hepatitis C
NMR Structure and Molecular Dynamics of the In-Plane Membrane Anchor of Nonstructural Protein 5A from Bovine Viral Diarrhea Virus(,).
Hepatitis C
No detection of the NS5B S282T mutation in treatment-naïve genotype 1 HCV/HIV-1 coinfected patients using deep sequencing.
Hepatitis C
No influence of antiretroviral therapy on the mutation rate of the HCV NS5B polymerase in HIV/HCV-coinfected patients.
Hepatitis C
NOD1 Participates in the Innate Immune Response Triggered by Hepatitis C Virus Polymerase.
Hepatitis C
Non-nucleoside analogue inhibitors bind to an allosteric site on HCV NS5B polymerase. Crystal structures and mechanism of inhibition.
Hepatitis C
Non-nucleoside benzimidazole-based allosteric inhibitors of the hepatitis C virus NS5B polymerase: inhibition of subgenomic hepatitis C virus RNA replicons in Huh-7 cells.
Hepatitis C
Non-nucleoside inhibitors binding to hepatitis C virus NS5B polymerase reveal a novel mechanism of inhibition.
Hepatitis C
Non-nucleoside inhibitors of hepatitis C virus polymerase: current progress and future challenges.
Hepatitis C
Non-nucleoside inhibitors of the hepatitis C virus NS5B polymerase: discovery and preliminary SAR of benzimidazole derivatives.
Hepatitis C
Non-nucleoside inhibitors of the hepatitis C virus NS5B polymerase: discovery of benzimidazole 5-carboxylic amide derivatives with low-nanomolar potency.
Hepatitis C
Non-nucleoside inhibitors of the hepatitis C virus NS5B RNA-dependant RNA polymerase: 2-aryl-3-heteroaryl-1,3-thiazolidin-4-one derivatives.
Hepatitis C
Nonstructural 5A Protein of Hepatitis C Virus Interferes with Toll-Like Receptor Signaling and Suppresses the Interferon Response in Mouse Liver.
Hepatitis C
Nonstructural 5A protein of hepatitis C virus modulates tumor necrosis factor alpha-stimulated nuclear factor kappa B activation.
Hepatitis C
Nonstructural protein 3-4A: the Swiss army knife of hepatitis C virus.
Hepatitis C
Nonstructural protein 5A (NS5A) and human replication protein A increase the processivity of hepatitis C virus NS5B polymerase activity in vitro.
Hepatitis C
Nonstructural protein 5A does not contribute to the resistance of hepatitis C virus replication to interferon alpha in cell culture.
Hepatitis C
Nonstructural protein 5A is incorporated into hepatitis C virus low-density particle through interaction with core protein and microtubules during intracellular transport.
Hepatitis C
Nonstructural protein 5A of hepatitis C virus inhibits the function of karyopherin beta3.
Hepatitis C
Nonstructural protein 5B of hepatitis C virus.
Hepatitis C
Nonstructural protein 5B promotes degradation of the NORE1A tumor suppressor to facilitate hepatitis C virus replication.
Hepatitis C
Nonstructural protein precursor NS4A/B from hepatitis C virus alters function and ultrastructure of host secretory apparatus.
Hepatitis C
Nonstructural proteins 4A and 4B of hepatitis C virus transactivate the interleukin 8 promoter.
Hepatitis C
Novel 4-thiazolidinones as non-nucleoside inhibitors of hepatitis C virus NS5B RNA-dependent RNA polymerase.
Hepatitis C
Novel fullerene derivatives as dual inhibitors of Hepatitis C virus NS5B polymerase and NS3/4A protease.
Hepatitis C
Novel guanosine derivatives against MERS CoV polymerase: An in silico perspective.
Hepatitis C
Novel inhibitors of hepatitis C virus RNA-dependent RNA polymerases.
Hepatitis C
Novel nonnucleoside inhibitor of hepatitis C virus RNA-dependent RNA polymerase.
Hepatitis C
NS5A, a nonstructural protein of hepatitis C virus, binds growth factor receptor-bound protein 2 adaptor protein in a Src homology 3 domain/ligand-dependent manner and perturbs mitogenic signaling.
Hepatitis C
NS5ATP9 Contributes to Inhibition of Cell Proliferation by Hepatitis C Virus (HCV) Nonstructural Protein 5A (NS5A) via MEK/Extracellular Signal Regulated Kinase (ERK) Pathway.
Hepatitis C
NS5B RNA Dependent RNA Polymerase Inhibitors: The Promising Approach to Treat Hepatitis C Virus Infections.
Hepatitis C
NTP-mediated nucleotide excision activity of hepatitis C virus RNA-dependent RNA polymerase.
Hepatitis C
Nuclear immunostaining of hepatitis C infected hepatocytes with monoclonal antibodies to C100-3 nonstructural protein. Comparison of immunogold silver staining with other immunohistochemical methods.
Hepatitis C
Nucleoside Inhibitors of Hepatitis C Virus NS5B Polymerase: a Systematic Review.
Hepatitis C
Nucleoside, Nucleotide, and Non-Nucleoside Inhibitors of Hepatitis C Virus NS5B RNA-Dependent RNA-Polymerase.
Hepatitis C
Nucleotide Analogues as Inhibitors of SARS-CoV-2 Polymerase, a Key Drug Target for COVID-19.
Hepatitis C
Nucleotide Analogues as Inhibitors of SARS-CoV-2 Polymerase.
Hepatitis C
Number and position of mutations in the interferon (IFN) sensitivity-determining region of the gene for nonstructural protein 5A correlate with IFN efficacy in hepatitis C virus genotype 1b infection.
Hepatitis C
OCIAD1 is a host mitochondrial substrate of the hepatitis C virus NS3-4A protease.
Hepatitis C
Oligomeric interaction of hepatitis C virus NS5B is critical for catalytic activity of RNA-dependent RNA polymerase.
Hepatitis C
Oligomerization and cooperative RNA synthesis activity of hepatitis C virus RNA-dependent RNA polymerase.
Hepatitis C
Ombitasvir/paritaprevir/ritonavir + dasabuvir +/- ribavirin in real world hepatitis C patients.
Hepatitis C
On the Origins of Hepatitis C Virus NS5B Polymerase Inhibitory Activity Using Machine Learning Approaches.
Hepatitis C
One-step RNA polymerase chain reaction for detection of hepatitis C virus RNA.
Hepatitis C
Only a small fraction of purified hepatitis C RNA-dependent RNA polymerase is catalytically competent: implications for viral replication and in vitro assays.
Hepatitis C
Open-label phase 2 study of faldaprevir, deleobuvir and ribavirin in Japanese treatment-naive patients with chronic hepatitis C virus genotype 1 infection.
Hepatitis C
Optimization of novel acyl pyrrolidine inhibitors of hepatitis C virus RNA-dependent RNA polymerase leading to a development candidate.
Hepatitis C
Optimization of thienopyrrole-based finger-loop inhibitors of the hepatitis C virus NS5B polymerase.
Hepatitis C
Optimizing choice of oral interferon-free treatment for genotype 1 hepatitis C virus using testing for NS5A resistance: a cost-utility analysis from the perspective of the Italian National Health Service.
Hepatitis C
Overall efficacy and safety results of sofosbuvir-based therapies in phase II and III studies.
Hepatitis C
Overall Structural Model of NS5A Protein from Hepatitis C Virus and Modulation by Mutations Confering Resistance of Virus Replication to Cyclosporin A.
Hepatitis C
PACSIN2 Interacts with Nonstructural Protein 5A and Regulates Hepatitis C Virus Assembly.
Hepatitis C
Parallel synthesis of 5-cyano-6-aryl-2-thiouracil derivatives as inhibitors for hepatitis C viral NS5B RNA-dependent RNA polymerase.
Hepatitis C
Parallel synthesis of pteridine derivatives as potent inhibitors for hepatitis C virus NS5B RNA-dependent RNA polymerase.
Hepatitis C
Partial reconstitution of hepatitis C virus RNA polymerization by heterologous expression of NS5B polymerase and template RNA in bacterial cell.
Hepatitis C
Persistent Innate Immune Stimulation Results in IRF3-Mediated but Caspase-Independent Cytostasis.
Hepatitis C
Pharmacoinformatics approach for investigation of alternative potential hepatitis C virus nonstructural protein 5B inhibitors.
Hepatitis C
Pharmacokinetic, Pharmacodynamic, and Drug-Interaction Profile of the Hepatitis C Virus NS5B Polymerase Inhibitor Sofosbuvir.
Hepatitis C
Pharmacokinetics of a Cholesterol-conjugated Aptamer Against the Hepatitis C Virus (HCV) NS5B Protein.
Hepatitis C
Pharmacokinetics of hepatitis C virus NS5A inhibitor JNJ-56914845 (GSK2336805) in subjects with hepatic impairment.
Hepatitis C
Phosphatidylinositol 4,5-Bisphosphate Is an HCV NS5A Ligand and Mediates Replication of the Viral Genome.
Hepatitis C
Phosphocholine conjugation: an unexpected in vivo conjugation pathway associated with hepatitis c ns5b inhibitors featuring a bicyclo[1.1.1]pentane.
Hepatitis C
Phosphoramidate dinucleosides as hepatitis C virus polymerase inhibitors.
Hepatitis C
Phosphoramidate prodrugs of 2'-C-methylcytidine for therapy of hepatitis C virus infection.
Hepatitis C
Phosphorylated tyrosine 93 of hepatitis C virus nonstructural protein 5A is essential for interaction with host c-Src and efficient viral replication.
Hepatitis C
Phosphorylation at the N-terminal finger subdomain of a viral RNA-dependent RNA polymerase.
Hepatitis C
Phosphorylation of hepatitis C virus nonstructural protein 5A modulates its protein interactions and viral RNA replication.
Hepatitis C
Phosphorylation of hepatitis C virus NS5A nonstructural protein: a new paradigm for phosphorylation-dependent viral RNA replication?
Hepatitis C
Phosphorylation of hepatitis C virus RNA polymerases ser29 and ser42 by protein kinase C-related kinase 2 regulates viral RNA replication.
Hepatitis C
Phosphorylation of hepatitis C virus-encoded nonstructural protein NS5A.
Hepatitis C
Phosphorylation of nonstructural 5A protein of hepatitis C virus: HCV group-specific hyperphosphorylation.
Hepatitis C
Phosphorylation of Serine 225 in Hepatitis C Virus NS5A Regulates Protein-Protein Interactions.
Hepatitis C
Phylogenetic and 2D/3D Analysis of HCV 1a NS4A Gene/Protein in Pakistani Isolates.
Hepatitis C
Phylogenetic and structural analysis of HCV nonstructural protein 4A from Pakistani patients.
Hepatitis C
Physicochemical properties of the nucleoside prodrug R1626 leading to high oral bioavailability.
Hepatitis C
Plasmon-waveguide resonance spectroscopy applied to three potential drug targets: cyclooxygenase-2, hepatitis C virus RNA polymerase and integrin alpha V beta 3.
Hepatitis C
Polymerases of hepatitis C viruses and flaviviruses: Structural and mechanistic insights and drug development.
Hepatitis C
Polymorphisms of NS5B protein relates to early clearance of hepatitis C virus by interferon plus ribavirin: a pilot study.
Hepatitis C
Population Pharmacokinetic Analysis for Daclatasvir and Asunaprevir in Japanese Subjects With Chronic Hepatitis C Virus Infection.
Hepatitis C
Potency and resistance analysis of hepatitis C virus NS5B polymerase inhibitor BMS-791325 on all major genotypes.
Hepatitis C
Potent inhibitors of subgenomic hepatitis C virus RNA replication through optimization of indole-N-acetamide allosteric inhibitors of the viral NS5B polymerase.
Hepatitis C
Preannealing of poly(A) template and oligo(dT) primer is not required for hepatitis C virus RNA-dependent RNA polymerase activity.
Hepatitis C
Preclinical and Clinical Resistance Profile of EDP-239, a Novel HCV NS5A Inhibitor.
Hepatitis C
Preclinical characterization of BMS-791325, an allosteric inhibitor of hepatitis C Virus NS5B polymerase.
Hepatitis C
Preclinical characterization of GS-9669, a thumb site II inhibitor of the hepatitis C virus NS5B polymerase.
Hepatitis C
Preclinical Characterization of JTK-853, a Novel Nonnucleoside Inhibitor of the Hepatitis C Virus RNA-Dependent RNA Polymerase.
Hepatitis C
Preclinical Characterization of PF-00868554, a Potent Nonnucleoside Inhibitor of the Hepatitis C Virus RNA-dependent RNA Polymerase.
Hepatitis C
Preclinical pharmacokinetics and metabolism of a potent non-nucleoside inhibitor of the hepatitis C virus NS5B polymerase.
Hepatitis C
Preclinical Profile and Clinical Efficacy of a Novel HCV NS5A Inhibitor, EDP-239.
Hepatitis C
Prediction of Small Molecule Inhibitors Targeting the Severe Acute Respiratory Syndrome Coronavirus-2 RNA-dependent RNA Polymerase.
Hepatitis C
Prevalence and characteristics of naturally occurring sofosbuvir resistance-associated variants in patients with hepatitis C virus genotype 1b infection.
Hepatitis C
Prevalence of blood-borne viral infections among autopsy cases in Jordan.
Hepatitis C
Prevalence of Hepatitis C Virus Subgenotypes 1a and 1b in Japanese Patients: Ultra-Deep Sequencing Analysis of HCV NS5B Genotype-Specific Region.
Hepatitis C
Primer on Hepatitis C Virus Resistance to Direct-Acting Antiviral Treatment: A Practical Approach for the Treating Physician.
Hepatitis C
Probing the "fingers" domain binding pocket of Hepatitis C virus NS5B RdRp and D559G resistance mutation via Molecular Docking, Molecular Dynamics simulation and binding free energy calculations.
Hepatitis C
Probing the substrate specificity of hepatitis C virus NS3 serine protease by using synthetic peptides.
Hepatitis C
Production and characterization of active hepatitis C virus RNA-dependent RNA polymerase.
Hepatitis C
Production of infectious hepatitis C virus by using RNA polymerase I-mediated transcription.
Hepatitis C
Profile of alisporivir and its potential in the treatment of hepatitis C.
Hepatitis C
Progress towards improving antiviral therapy for hepatitis C with hepatitis C virus polymerase inhibitors. Part I: Nucleoside analogues.
Hepatitis C
Promoter/origin structure of the complementary strand of hepatitis C virus genome.
Hepatitis C
Properties of hepatitis C virus minigenome containing mutated 5'UTR region and luciferase transgene.
Hepatitis C
Protease inhibitor-resistant hepatitis C virus mutants with reduced fitness from impaired production of infectious virus.
Hepatitis C
Protein kinase C-related kinase 2 regulates hepatitis C virus RNA polymerase function by phosphorylation.
Hepatitis C
Proteolytic processing and membrane association of putative nonstructural proteins of hepatitis C virus.
Hepatitis C
PSI-7851, a pronucleotide of beta-D-2'-deoxy-2'-fluoro-2'-C-methyluridine monophosphate, is a potent and pan-genotype inhibitor of hepatitis C virus replication.
Hepatitis C
Purification of Zika virus RNA-dependent RNA polymerase and its use to identify small-molecule Zika inhibitors.
Hepatitis C
Pyridine Carboxamides: Potent Palm Site Inhibitors of HCV NS5B Polymerase.
Hepatitis C
Pyrophosphorolytic excision of nonobligate chain terminators by hepatitis C virus NS5B polymerase.
Hepatitis C
QSAR study of C allosteric binding site of HCV NS5B polymerase inhibitors by support vector machine.
Hepatitis C
QSAR study of HCV NS5B polymerase inhibitors using the genetic algorithm-multiple linear regression (GA-MLR).
Hepatitis C
Quantifying the Diversification of Hepatitis C Virus (HCV) during Primary Infection: Estimates of the In Vivo Mutation Rate.
Hepatitis C
Quantitative structure and bioactivity relationship study on HCV NS5B polymerase inhibitors.
Hepatitis C
R-1626, a specific oral NS5B polymerase inhibitor of hepatitis C virus.
Hepatitis C
R1626 plus peginterferon Alfa-2a provides potent suppression of hepatitis C virus RNA and significant antiviral synergy in combination with ribavirin.
Hepatitis C
RacGTPase-activating protein 1 interacts with hepatitis C virus polymerase NS5B to regulate viral replication.
Hepatitis C
Randomized, placebo-controlled, single-ascending-dose study of BMS-791325, a hepatitis C virus (HCV) NS5B polymerase inhibitor, in HCV genotype 1 infection.
Hepatitis C
Rapid and strong antiviral activity of the non-nucleosidic NS5B polymerase inhibitor BI 207127 in combination with peginterferon alfa 2a and ribavirin.
Hepatitis C
Rate-limiting pyrophosphate release by Hepatitis C Virus polymerase NS5B improves fidelity.
Hepatitis C
Real-world effectiveness and safety of sofosbuvir and nonstructural protein 5A inhibitors for chronic hepatitis C genotype 1, 2, 3, 4, or 6: a multicentre cohort study.
Hepatitis C
Recent advances in discovery and development of promising therapeutics against hepatitis C virus NS5B RNA-dependent RNA polymerase.
Hepatitis C
Recent advances in the analysis of HCV NS5B RNA-dependent RNA polymerase.
Hepatitis C
Recent advances in the chromatographic determination of the most commonly used anti-hepatitis C drug Sofosbuvir and its co-administered drugs in human plasma.
Hepatitis C
Recent advances in the development of NS5B polymerase inhibitors for the treatment of hepatitis C virus infection.
Hepatitis C
Recent advances on the synthesis of hepatitis C virus NS5B RNA-dependent RNA-polymerase inhibitors.
Hepatitis C
Recent progress in the development of inhibitors of the hepatitis C virus RNA-dependent RNA polymerase.
Hepatitis C
Recent progress in the development of selected hepatitis C virus NS3.4A protease and NS5B polymerase inhibitors.
Hepatitis C
Recombinant HCV NS3 and NS5B enzymes exhibit multiple posttranslational modifications for potential regulation.
Hepatitis C
Recombinant infectious bursal disease virus carrying hepatitis C virus epitopes.
Hepatitis C
Recombinant viral RdRps can initiate RNA synthesis from circular templates.
Hepatitis C
Reconstitution and Functional Analysis of a Full-Length Hepatitis C Virus NS5B Polymerase on a Supported Lipid Bilayer.
Hepatitis C
Recrutement des kinases PI4KIII aux organelles de réplication virale au cours de l'infection par le poliovirus et d'autres virus à ARN de polarité positive.
Hepatitis C
Regulation of De Novo Initiated RNA Synthesis in the Hepatitis C Virus RNA Dependent RNA Polymerase by Intermolecular Interactions.
Hepatitis C
Regulation of Hepatitis C Virus Replication by Nuclear Translocation of Nonstructural 5A Protein and Transcriptional Activation of Host Genes.
Hepatitis C
Regulation of hepatitis C virus replication by the core protein through its interaction with viral RNA polymerase.
Hepatitis C
Regulation of mRNA translation and cellular signaling by hepatitis C virus nonstructural protein NS5A.
Hepatitis C
Regulation of neuronal proapoptotic potassium currents by the hepatitis C virus nonstructural protein 5A.
Hepatitis C
Regulation of the hepatitis C virus RNA replicase by endogenous lipid peroxidation.
Hepatitis C
Regulation of the production of infectious genotype 1a hepatitis C virus by NS5A domain III.
Hepatitis C
Reliability of the third-generation recombinant immunoblot assay for hepatitis C virus.
Hepatitis C
Repositioning of RdRp Inhibitors against HCV NS5B Polymerase Utilizing Structure-Based Molecular Docking.
Hepatitis C
Resistance outside the substrate envelope: hepatitis C NS3/4A protease inhibitors.
Hepatitis C
Resistance profile of a hepatitis C virus RNA-dependent RNA polymerase benzothiadiazine inhibitor.
Hepatitis C
Resistance to excision determines efficiency of hepatitis C virus RNA-dependent RNA polymerase inhibition by nucleotide analogs.
Hepatitis C
Resistance to HCV nucleoside analogue inhibitors of hepatitis C virus RNA-dependent RNA polymerase.
Hepatitis C
Resistance to nucleotide analogue inhibitors of hepatitis C virus NS5B: mechanisms and clinical relevance.
Hepatitis C
Resolution of the interaction mechanisms and characteristics of non-nucleoside inhibitors of hepatitis C virus polymerase.
Hepatitis C
Retraction. Oligomeric interaction of hepatitis C virus NS5B is critical for catalytic activity of RNA-dependent RNA polymerase.
Hepatitis C
Reversal of nonstructural protein 3-specific CD4(+) T cell dysfunction in patients with persistent hepatitis C virus infection.
Hepatitis C
Review article: novel therapeutic options for chronic hepatitis C.
Hepatitis C
Ribavirin mode of action in chronic hepatitis C: from clinical use back to molecular mechanisms.
Hepatitis C
Ribavirin resistance in hepatitis C virus replicon-containing cell lines conferred by changes in the cell line or mutations in the replicon RNA.
Hepatitis C
Ribonucleotide reductase M2 promotes RNA replication of hepatitis C virus by protecting NS5B protein from hPLIC1-dependent proteasomal degradation.
Hepatitis C
RNA polymerase as an antiviral target of hepatitis C virus.
Hepatitis C
RNA template-mediated inhibition of hepatitis C virus RNA-dependent RNA polymerase activity.
Hepatitis C
RNA unwinding activity of the hepatitis C virus NS3 helicase is modulated by the NS5B polymerase.
Hepatitis C
RNA-binding protein hnRNP D modulates internal ribosome entry site-dependent translation of hepatitis C virus RNA.
Hepatitis C
RNA-dependent RNA polymerase activity of the soluble recombinant hepatitis C virus NS5B protein truncated at the C-terminal region.
Hepatitis C
RNA-dependent RNA polymerase encoded by hepatitis C virus: biomedical applications.
Hepatitis C
RNA-dependent RNA polymerase of hepatitis C virus binds to its coding region RNA stem-loop structure, 5BSL3.2, and its negative strand.
Hepatitis C
RNA-dependent RNA polymerase of hepatitis C virus.
Hepatitis C
RNA-dependent RNA polymerase of hepatitis C virus: study on inhibition by alpha,gamma-diketo acid derivatives.
Hepatitis C
RNA-dependent RNA polymerases from different hepatitis C virus genotypes reveal distinct biochemical properties and drug susceptibilities.
Hepatitis C
Robust antiviral activity of R1626, a novel nucleoside analog: a randomized, placebo-controlled study in patients with chronic hepatitis C.
Hepatitis C
Role for TBC1D20 and Rab1 in hepatitis C virus replication via interaction with lipid droplet-bound nonstructural protein 5A.
Hepatitis C
Safety analysis of sofosbuvir and ledipasvir for treating hepatitis C.
Hepatitis C
Safety, pharmacokinetics and antiviral activity of AT-527, a novel purine nucleotide prodrug, in HCV-infected subjects with and without cirrhosis.
Hepatitis C
Safety, pharmacokinetics and antiviral effect of BILB 1941, a novel hepatitis C virus RNA polymerase inhibitor, after 5 days oral treatment.
Hepatitis C
Safety, tolerability, and pharmacokinetics of AL-335 in healthy volunteers and hepatitis C virus-infected subjects.
Hepatitis C
SAR and mode of action of novel non-nucleoside inhibitors of Hepatitis C NS5b RNA polymerase.
Hepatitis C
SAR studies on a series of N-benzyl-4-heteroaryl-1-(phenylsulfonyl)piperazine-2-carboxamides: Potent inhibitors of the polymerase enzyme (NS5B) of the hepatitis C virus.
Hepatitis C
Screening and molecular docking of selected phytochemicals against NS5B polymerase of hepatitis c virus.
Hepatitis C
Screening for hepatitis C virus non-nucleotide resistance mutations in treatment-naive women.
Hepatitis C
Screening of blood donations by hepatitis C virus polymerase chain reaction (HCV-PCR) improves safety of blood products by window period reduction.
Hepatitis C
Screening of hepatitis C NS5B polymerase inhibitors containing benzothiadiazine core: a steered molecular dynamics.
Hepatitis C
Secondary structure of the 3' terminus of hepatitis C virus minus-strand RNA.
Hepatitis C
Selected replicon variants with low-level in vitro resistance to the hepatitis C virus NS5B polymerase inhibitor PSI-6130 lack cross-resistance with R1479.
Hepatitis C
Selection and characterization of hepatitis C virus replicons dually resistant to the polymerase and protease inhibitors HCV-796 and boceprevir (SCH 503034).
Hepatitis C
Selection of 3'-template bases and initiating nucleotides by hepatitis C virus NS5B RNA-dependent RNA polymerase.
Hepatitis C
Selection of DNA aptamers that bind the RNA-dependent RNA polymerase of hepatitis C virus and inhibit viral RNA synthesis in vitro.
Hepatitis C
Selection of replicon variants resistant to ACH-806, a novel hepatitis C virus inhibitor with no cross-resistance to NS3 protease and NS5B polymerase inhibitors.
Hepatitis C
Selection of RNA aptamers that are specific and high-affinity ligands of the hepatitis C virus RNA-dependent RNA polymerase.
Hepatitis C
Selective stimulation of hepatitis C virus and pestivirus NS5B RNA polymerase activity by GTP.
Hepatitis C
Sequence variation in hepatitis C virus nonstructural protein 5A predicts clinical outcome of pegylated interferon/ribavirin combination therapy.
Hepatitis C
Sequential Phosphorylation of the Hepatitis C Virus NS5A Protein Depends on NS3-Mediated Autocleavage between NS3 and NS4A.
Hepatitis C
Sequential S232/S235/S238 Phosphorylation of the Hepatitis C Virus Nonstructural Protein 5A.
Hepatitis C
Ser(2194) is a highly conserved major phosphorylation site of the hepatitis C virus nonstructural protein NS5A.
Hepatitis C
Seraprevir and sofosbuvir for treatment of chronic hepatitis C virus infection: A single-arm, open-label, phase 3 trial.
Hepatitis C
Serine 229 balances the hepatitis C virus nonstructural protein NS5A between hypo- and hyper-phosphorylated states.
Hepatitis C
Serine 235 Is the Primary NS5A Hyperphosphorylation Site Responsible for Hepatitis C Virus Replication.
Hepatitis C
Severe acute respiratory syndrome coronavirus protein nsp1 is a novel eukaryotic translation inhibitor that represses multiple steps of translation initiation.
Hepatitis C
Severe acute respiratory syndrome coronavirus replication inhibitor that interferes with the nucleic Acid unwinding of the viral helicase.
Hepatitis C
Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity.
Hepatitis C
Significance of specific antibody assay for genotyping of hepatitis C virus.
Hepatitis C
Silibinin and related compounds are direct inhibitors of hepatitis C virus RNA-dependent RNA polymerase.
Hepatitis C
Similar compliance and effect of treatment in chronic hepatitis C resulting from intravenous drug use in comparison with other infection causes.
Hepatitis C
Simple but highly effective three-dimensional chemical-feature-based pharmacophore model for diketo acid derivatives as hepatitis C virus RNA-dependent RNA polymerase inhibitors.
Hepatitis C
Simultaneous detection of both hepatitis B virus DNA and hepatitis C virus RNA using a combined one-step polymerase chain reaction technique.
Hepatitis C
Single-chain antibodies against a plant viral RNA-dependent RNA polymerase confer virus resistance.
Hepatitis C
Sofosbuvir (GS-7977) plus peginterferon/ribavirin in treatment-naïve patients with HCV genotype 1: A randomized, 28-day, dose-ranging trial.
Hepatitis C
Sofosbuvir as a potential alternative to treat the SARS-CoV-2 epidemic.
Hepatitis C
Sofosbuvir for the treatment of chronic hepatitis C virus infection.
Hepatitis C
Sofosbuvir plus ribavirin with or without peginterferon for the treatment of hepatitis C virus: Results from a phase 3b study in China.
Hepatitis C
Sofosbuvir with pegylated interferon alfa-2a and ribavirin for treatment-naive patients with hepatitis C genotype-1 infection (ATOMIC): an open-label, randomised, multicentre phase 2 trial.
Hepatitis C
Sofosbuvir, a novel nucleotide analogue inhibitor used for the treatment of hepatitis C virus.
Hepatitis C
Sofosbuvir, a NS5B polymerase inhibitor in the treatment of hepatitis C: a review of its clinical potential.
Hepatitis C
Sofosbuvir-Induced Erythrodermic Pityriasis Rubra Pilaris-Like Drug Eruption.
Hepatitis C
Sofosbuvir/Velpatasvir/Voxilaprevir: A Review in Chronic Hepatitis C.
Hepatitis C
Sofosbuvir/Velpatasvir: A Review in Chronic Hepatitis C.
Hepatitis C
Sofosbuvir: A novel treatment option for chronic hepatitis C infection.
Hepatitis C
Sofosbuvir: a review of its use in patients with chronic hepatitis C.
Hepatitis C
Sofosbuvir: first global approval.
Hepatitis C
Solid-phase synthesis and screening of macrocyclic nucleotide-hybrid compounds targeted to hepatitis C NS5B.
Hepatitis C
Specific inhibitors of HCV polymerase identified using an NS5B with lower affinity for template/primer substrate.
Hepatitis C
Specific interaction between the hepatitis C virus NS5B RNA polymerase and the 3' end of the viral RNA.
Hepatitis C
Specific targeted antiviral therapy for hepatitis C.
Hepatitis C
Specificity and mechanism analysis of hepatitis C virus RNA-dependent RNA polymerase.
Hepatitis C
Sphingomyelin activates hepatitis C virus RNA polymerase in a genotype-specific manner.
Hepatitis C
Stereoselective synthesis and biological evaluation as inhibitors of hepatitis C virus RNA polymerase of GSK3082 analogues with structural diversity at the 5-position.
Hepatitis C
Stimulation of hepatitis C virus (HCV) nonstructural protein 3 (NS3) helicase activity by the NS3 protease domain and by HCV RNA-dependent RNA polymerase.
Hepatitis C
Structural analysis of the hepatitis C virus RNA polymerase in complex with ribonucleotides.
Hepatitis C
Structural basis for resistance of the genotype 2b hepatitis C virus NS5B polymerase to site A non-nucleoside inhibitors.
Hepatitis C
Structural insights into NS5B protein of novel equine hepaciviruses and pegiviruses complexed with polymerase inhibitors.
Hepatitis C
Structure and function of the membrane anchor domain of hepatitis C virus nonstructural protein 5A.
Hepatitis C
Structure and function of the Zika virus full-length NS5 protein.
Hepatitis C
Structure of hepatitis C virus polymerase in complex with primer-template RNA.
Hepatitis C
Structure-activity relationship (SAR) development and discovery of potent indole-based inhibitors of the hepatitis C virus (HCV) NS5B polymerase.
Hepatitis C
Structure-activity relationship of purine ribonucleosides for inhibition of hepatitis C virus RNA-dependent RNA polymerase.
Hepatitis C
Structure-Activity Relationships in the Development of Allosteric Hepatitis C Virus RNA-Dependent RNA Polymerase Inhibitors: Ten Years of Research.
Hepatitis C
Structure-based design of a benzodiazepine scaffold yields a potent allosteric inhibitor of hepatitis C NS5B RNA polymerase.
Hepatitis C
Structure-based design, synthesis, and biological evaluation of 1,1-dioxoisothiazole and benzo[b]thiophene-1,1-dioxide derivatives as novel inhibitors of hepatitis C virus NS5B polymerase.
Hepatitis C
Structure-based discovery of pyrazolobenzothiazine derivatives as inhibitors of hepatitis C virus replication.
Hepatitis C
Structure-based virtual screening, synthesis and SAR of novel inhibitors of hepatitis C virus NS5B polymerase.
Hepatitis C
Studies of benzothiadiazine derivatives as hepatitis C virus NS5B polymerase inhibitors using 3D-QSAR, molecular docking and molecular dynamics.
Hepatitis C
Studies on acyl pyrrolidine inhibitors of HCV RNA-dependent RNA polymerase to identify a molecule with replicon antiviral activity.
Hepatitis C
Study Design Characteristics and Pharmacological Mechanisms in International Clinical Trials Registry Platform: Registered Clinical Trials on Antiviral Drugs for COVID-19.
Hepatitis C
Substituted benzothiadizine inhibitors of Hepatitis C virus polymerase.
Hepatitis C
Substrate complexes of hepatitis C virus RNA polymerase (HC-J4): structural evidence for nucleotide import and de-novo initiation.
Hepatitis C
Suppression of hepatitis C virus replication by protein kinase C-related kinase 2 inhibitors that block phosphorylation of viral RNA polymerase.
Hepatitis C
Suppression of Viral RNA Binding and the Assembly of Infectious Hepatitis C Virus Particles in vitro by Cyclophilin Inhibitors.
Hepatitis C
Surface plasmon resonance as a tool to select potent drug candidates for hepatitis C virus NS5B polymerase.
Hepatitis C
Syntheses of four peptides from the immunodominant region of hepatitis C viral pathogens using PS-TTEGDA support for the investigation of HCV infection in human blood.
Hepatitis C
Syntheses of immunodominant peptide regions of hepatitis C viral pathogens using PS-BDODMA resin: a single peptide derived from the conserved domain (E2/NS1) was highly effective in detecting anti-HCV antibodies.
Hepatitis C
Synthesis and Anti-HCV Activities of 4'-Fluoro-2'-Substituted Uridine Triphosphates and Nucleotide Prodrugs: Discovery of 4'-Fluoro-2'- C-methyluridine 5'-Phosphoramidate Prodrug (AL-335) for the Treatment of Hepatitis C Infection.
Hepatitis C
Synthesis and anti-hepatitis C virus activity of 2'(beta)-hydroxyethyl and 4'(alpha)-hydroxymethyl carbodine analogues.
Hepatitis C
Synthesis and Antiviral Activity of a Series of 2'-C-Methyl-4'-thionucleoside Monophosphate Prodrugs.
Hepatitis C
Synthesis and antiviral properties of novel 7-heterocyclic substituted 7-deaza-adenine nucleoside inhibitors of Hepatitis C NS5B polymerase.
Hepatitis C
Synthesis and Antiviral Properties of Novel Tetracyclic Nucleoside Inhibitors of Hepatitis C NS5B Polymerase.
Hepatitis C
Synthesis and biological activity of heteroaryl 3-(1,1-dioxo-2H-(1,2,4)-benzothiadizin-3-yl)-4-hydroxy-2(1H)-quinolinone derivatives as hepatitis C virus NS5B polymerase inhibitors.
Hepatitis C
Synthesis and Biological Characterization of Aryl Uracil Inhibitors of Hepatitis C Virus NS5B Polymerase: Discovery of ABT-072, a trans-Stilbene Analog with Good Oral Bioavailability.
Hepatitis C
Synthesis and Biological Characterization of B-Ring Amino Analogues of Potent Benzothiadiazine Hepatitis C Virus Polymerase Inhibitors.
Hepatitis C
Synthesis and evaluation of novel phosphoramidate prodrugs of 2'-methyl cytidine as inhibitors of hepatitis c virus NS5B polymerase.
Hepatitis C
Synthesis and evaluation of NS5A inhibitors containing diverse heteroaromatic cores.
Hepatitis C
Synthesis and evaluation of S-acyl-2-thioethyl esters of modified nucleoside 5'-monophosphates as inhibitors of hepatitis C virus RNA replication.
Hepatitis C
Synthesis and properties of (alpha-P-borano)-nucleoside 5'-triphosphate analogues as potential antiviral agents.
Hepatitis C
Synthesis and SAR optimization of diketo acid pharmacophore for HCV NS5B polymerase inhibition.
Hepatitis C
Synthesis and SAR studies of novel heteroaryl fused tetracyclic indole-diamide compounds: potent allosteric inhibitors of the hepatitis C virus NS5B polymerase.
Hepatitis C
Synthesis of 2,3-Dideoxy-2-fluoro-2,3-endo-methylene- and 2,3-Dideoxy-2-fluoro-3-C-hydroxymethyl-2,3-endo-methylene-pentofuranoses and Their Use in the Preparation of Conformationally Locked Bicyclic Nucleosides.
Hepatitis C
Synthesis of deleobuvir, a potent hepatitis C virus polymerase inhibitor, and its major metabolites labeled with carbon-13 and carbon-14.
Hepatitis C
Synthesis of potent and broad genotypically active NS5B HCV non-nucleoside inhibitors binding to the thumb domain allosteric site 2 of the viral polymerase.
Hepatitis C
Synthesis, biological evaluation and molecular modeling of 2-Hydroxyisoquinoline-1,3-dione analogues as inhibitors of HIV reverse transcriptase associated ribonuclease H and polymerase.
Hepatitis C
Synthesis, in vitro and in silico NS5B polymerase inhibitory activity of benzimidazole derivatives.
Hepatitis C
Targeting the RdRp of Emerging RNA Viruses: The Structure-Based Drug Design Challenge.
Hepatitis C
Template requirement and initiation site selection by hepatitis C virus polymerase on a minimal viral RNA template.
Hepatitis C
Template requirements and binding of hepatitis C virus NS5B polymerase during in vitro RNA synthesis from the 3'-end of virus minus-strand RNA.
Hepatitis C
Template requirements for de novo RNA synthesis by hepatitis C virus nonstructural protein 5B polymerase on the viral X RNA.
Hepatitis C
Template requirements for RNA synthesis by a recombinant hepatitis C virus RNA-dependent RNA polymerase.
Hepatitis C
Template/primer requirements and single nucleotide incorporation by hepatitis C virus nonstructural protein 5B polymerase.
Hepatitis C
Terminal nucleotidyl transferase activity of recombinant Flaviviridae RNA-dependent RNA polymerases: implication for viral RNA synthesis.
Hepatitis C
Tetrahydrobenzothiophene inhibitors of hepatitis C virus NS5B polymerase.
Hepatitis C
The "interferon sensitivity determining region" of hepatitis C virus is a stable sequence element.
Hepatitis C
The A150V Polymorphism of Genotype 3 Hepatitis C Virus Polymerase Inhibits Interferon Alfa by Suppressing Protein Kinase R Activation.
Hepatitis C
The amino terminal deletion mutants of hepatitis C virus nonstructural protein NS5A function as transcriptional activators in yeast.
Hepatitis C
The antiviral protein viperin inhibits hepatitis C virus replication via interaction with nonstructural protein 5A.
Hepatitis C
The C terminus of hepatitis C virus NS4A encodes an electrostatic switch that regulates NS5A hyperphosphorylation and viral replication.
Hepatitis C
The C-terminal alpha-helix domain of apolipoprotein E is required for interaction with nonstructural protein 5A and assembly of hepatitis C virus.
Hepatitis C
The C-terminal hydrophobic domain of hepatitis C virus RNA polymerase NS5B can be replaced with a heterologous domain of poliovirus protein 3A.
Hepatitis C
The C-terminal transmembrane domain of hepatitis C virus (HCV) RNA polymerase is essential for HCV replication in vivo.
Hepatitis C
The conserved lysine 151 of HCV NS5B modulates viral genome replication and infectious virus production.
Hepatitis C
The crystal structure of the RNA-dependent RNA polymerase from human rhinovirus: a dual function target for common cold antiviral therapy.
Hepatitis C
The design, synthesis and biological evaluations of C-6 or C-7 substituted 2-hydroxyisoquinoline-1,3-diones as inhibitors of hepatitis C virus.
Hepatitis C
The design, synthesis, and antiviral activity of 4'-azidocytidine analogues against hepatitis C virus replication: the discovery of 4'-azidoarabinocytidine.
Hepatitis C
The design, synthesis, and antiviral activity of monofluoro and difluoro analogues of 4'-azidocytidine against hepatitis C virus replication: the discovery of 4'-azido-2'-deoxy-2'-fluorocytidine and 4'-azido-2'-dideoxy-2',2'-difluorocytidine.
Hepatitis C
The discovery and structure-activity relationships of pyrano[3,4-b]indole based inhibitors of hepatitis C virus NS5B polymerase.
Hepatitis C
The discovery and structure-activity relationships of pyrano[3,4-b]indole-based inhibitors of hepatitis C virus NS5B polymerase.
Hepatitis C
The discovery of finger loop inhibitors of the hepatitis C virus NS5B polymerase: status and prospects for novel HCV therapeutics.
Hepatitis C
The Discovery of Potent Nonstructural Protein 5A (NS5A) Inhibitors with a Unique Resistance Profile-Part?1.
Hepatitis C
The Disordered Region of the HCV Protein NS5A: Conformational Dynamics, SH3 Binding, and Phosphorylation.
Hepatitis C
The Effect of Mild to Moderate Renal Impairment on the Pharmacokinetics of the Nucleoside Analog Hepatitis C Virus Polymerase Inhibitor Mericitabine.
Hepatitis C
The essential role of C-terminal residues in regulating the activity of hepatitis C virus RNA-dependent RNA polymerase.
Hepatitis C
The exploding field of the HCV polymerase non-nucleoside inhibitors: summary of a first generation compounds.
Hepatitis C
The HCV NS5B Nucleoside and Non-Nucleoside Inhibitors.
Hepatitis C
The hepatitis C viral nonstructural protein 5A stabilizes growth-regulatory human transcripts.
Hepatitis C
The hepatitis C virus core protein can modulate RNA-dependent RNA synthesis by the 2a polymerase.
Hepatitis C
The Hepatitis C Virus NS5A Stimulates NS5B During In Vitro RNA Synthesis in a Template Specific Manner.
Hepatitis C
The hepatitis C virus NS5B RNA-dependent RNA polymerase activity and susceptibility to inhibitors is modulated by metal cations.
Hepatitis C
The hepatitis C virus replicon presents a higher barrier to resistance to nucleoside analogs than to nonnucleoside polymerase or protease inhibitors.
Hepatitis C
The hepatitis C virus RNA-dependent RNA polymerase directs incoming nucleotides to its active site through magnesium-dependent dynamics within its F motif.
Hepatitis C
The hepatitis C virus RNA-dependent RNA polymerase membrane insertion sequence is a transmembrane segment.
Hepatitis C
The juxtamembrane sequence of the Hepatitis C virus polymerase can affect RNA synthesis and inhibition by allosteric polymerase inhibitors.
Hepatitis C
The Long-Term Effect of Hepatitis C Virus on the Outcome of Live-Donor Kidney Transplant Recipients. A Retrospective Study.
Hepatitis C
The mechanism of action of beta-D-2'-deoxy-2'-fluoro-2'-C-methylcytidine involves a second metabolic pathway leading to beta-D-2'-deoxy-2'-fluoro-2'-C-methyluridine 5'-triphosphate, a potent inhibitor of the hepatitis C virus RNA-dependent RNA polymerase.
Hepatitis C
The molecular and structural basis of advanced antiviral therapy for hepatitis C virus infection.
Hepatitis C
The non-structural 5A protein of hepatitis C virus.
Hepatitis C
The nonstructural NS5A protein of hepatitis C virus: an expanding, multifunctional role in enhancing hepatitis C virus pathogenesis.
Hepatitis C
The prevalence of hepatitis C in survivors of paediatric malignancy.
Hepatitis C
The protease inhibitor, GS-9256, and non-nucleoside polymerase inhibitor tegobuvir alone, with ribavirin, or pegylated interferon plus ribavirin in hepatitis C.
Hepatitis C
The RNA-dependent RNA polymerases of different members of the family Flaviviridae exhibit similar properties in vitro.
Hepatitis C
The Stimulatory Mechanism of Hepatitis C Virus NS5A Protein on the NS5B Catalyzed Replication Reaction In Vitro.
Hepatitis C
The successful immune response against hepatitis C nonstructural protein 5A (NS5A) requires heterologous DNA/protein immunization.
Hepatitis C
The synthesis and evaluation of a novel class of (E)-3-(1-cyclohexyl-1H-pyrazol-3-yl)-2-methylacrylic acid hepatitis C virus polymerase NS5B inhibitors.
Hepatitis C
The Viral Polymerase Inhibitor 2'-C-Methylcytidine Inhibits Norwalk Virus Replication and Protects against Norovirus-Induced Diarrhea and Mortality in a Mouse Model.
Hepatitis C
Therapy of hepatitis C: other options.
Hepatitis C
Thumb inhibitor binding eliminates functionally important dynamics in the hepatitis C virus RNA polymerase.
Hepatitis C
Thumb Site 2 Inhibitors of Hepatitis C Viral RNA-Dependent RNA Polymerase Allosterically Block the Transition from Initiation to Elongation.
Hepatitis C
Time to viral suppression is not related to achievement of SVR12 in HCV GT1-infected patients treated with ombitasvir/paritaprevir/ritonavir and dasabuvir with or without ribavirin.
Hepatitis C
Tissue hepatitis C virus RNA quantification and protein expression help identify early hepatitis C virus recurrence after liver transplantation.
Hepatitis C
TMC647055, a Potent Nonnucleoside Hepatitis C Virus NS5B Polymerase Inhibitor with Cross-Genotypic Coverage.
Hepatitis C
Transfection and expression of HCV-NS5B gene in Huh-7 cells.
Hepatitis C
Treatment of hepatitis C virus infection.
Hepatitis C
Treatment Options in Hepatitis C.
Hepatitis C
Two crucial early steps in RNA synthesis by the hepatitis C virus polymerase involve a dual role of residue 405.
Hepatitis C
Two RNA tunnel inhibitors bind in highly conserved sites in Dengue virus NS5 polymerase: structural and functional studies.
Hepatitis C
Ubiquitin ligase Fbw7 restricts the replication of hepatitis C virus by targeting NS5B for ubiquitination and degradation.
Hepatitis C
Understanding effect site pharmacology of uprifosbuvir, a hepatitis C virus nucleoside inhibitor: Case study of a multidisciplinary modeling approach in drug development.
Hepatitis C
Understanding the drug resistance mechanism of hepatitis C virus NS5B to PF-00868554 due to mutations of the 423 site: a computational study.
Hepatitis C
Understanding the mechanisms of viral RNA synthesis: towards the discovery of new inhibitors.
Hepatitis C
Update on hepatitis C virus resistance to direct-acting antiviral agents.
Hepatitis C
Using the Hepatitis C Virus RNA-Dependent RNA Polymerase as a Model to Understand Viral Polymerase Structure, Function and Dynamics.
Hepatitis C
Validation and Application of a Liquid Chromatography-Tandem Mass Spectrometry Method To Determine the Concentrations of Sofosbuvir Anabolites in Cells.
Hepatitis C
VAPC, an Human Endogenous Inhibitor for Hepatitis C Virus (HCV) Infection, Is Intrinsically Unstructured but Forms a "Fuzzy Complex" with HCV NS5B.
Hepatitis C
Variability of the polymerase gene (NS5B) in hepatitis C virus-infected women.
Hepatitis C
Variations of hepatitis C virus NS5B sequence (nucleotides 8261-8566) do not correlate with response to interferon-alpha therapy.
Hepatitis C
Vinexin ? Interacts with Hepatitis C Virus NS5A, Modulating Its Hyperphosphorylation To Regulate Viral Propagation.
Hepatitis C
Viral double-strand RNA-binding proteins can enhance innate immune signaling by toll-like Receptor 3.
Hepatitis C
Viral factors influencing the response to the combination therapy of peginterferon plus ribavirin in chronic hepatitis C.
Hepatitis C
Viral load is associated with abnormal serum levels of micronutrients and glutathione and glutathione-dependent enzymes in genotype 3 HCV patients.
Hepatitis C
Viral replication. Structural basis for RNA replication by the hepatitis C virus polymerase.
Hepatitis C
Viral targets of acylguanidines.
Hepatitis C
Viral, host and interferon-related factors modulating the effect of interferon therapy for hepatitis C virus infection.
Hepatitis C
Virologic escape in HCV genotype 1-infected patients receiving daclatasvir plus ribavirin and peginterferon alfa-2a or alfa-2b.
Hepatitis C
VX-222, a non-nucleoside NS5B polymerase inhibitor, in telaprevir-based regimens for genotype 1 hepatitis C virus infection.
Hepatitis C
Water-soluble Fullerene Derivatives for Drug Discovery.
Hepatitis C
West Nile virus strain Kunjin NS5 polymerase is a phosphoprotein localized at the cytoplasmic site of viral RNA synthesis.
Hepatitis C
Worldwide distribution of the NS3 gene 80K polymorphism among circulating hepatitis C genotype 1 viruses: implication for simeprevir usage.
Hepatitis C
[2'fluoro derivatives of nucleosides as substrates of viral replicative nucleotide polymerases].
Hepatitis C
[Active components of Ligustrum lucidum inhibiting hepatitis C virus replicase activity].
Hepatitis C
[Cloning and expressing of HCV NS5 partial gene and dynamic changes of anti-NS5]
Hepatitis C
[Cloning of genes transactivated by nonstructural protein 4A of hepatitis C virus.]
Hepatitis C
[Crystal structure of hepatitis C virus NS5B polymerase]
Hepatitis C
[Effect of hepatitis C virus nonstructural protein 5A and its domains II on hepatocyte gluconeogenesis in mice].
Hepatitis C
[Expression of a HCV multi-epitopes antigen gene and study on its immunogenicity]
Hepatitis C
[Future perspective in the treatment of chronic hepatitis C].
Hepatitis C
[HCV NS5A protein down-regulates hepcidin gene expression and increases hepatic intracellular iron storage].
Hepatitis C
[Hepatitis C virus NS5A protein upregulates survivin gene expression]
Hepatitis C
[Interferon resistance and ISDR (interferon sensitivity determining region)]
Hepatitis C
[Involvement of nonstructural protein 5A and lipids on production of hepatitis C virus particles]
Hepatitis C
[Molecular evolutionary analysis of GB viruses and hepatitis G virus]
Hepatitis C
[Non-hydrolysable analogs of inorganic pyrophopshate as inhibitors of hepatitis C virus RNA-dependent RNA-polymerase].
Hepatitis C
[Polymerase chain reaction in hepatitis C: increased sensitivity via amplification of shorter cDNA fragments]
Hepatitis C
[Serological study of hepatitis C virus NS5 protein epitopes and their clinical and diagnostic significance]
Hepatitis C
[Significance of hepatitis C virus baseline polymorphism during the antiviral therapy].
Hepatitis C
[Study of the subcellular location of the human gene 6 transactivated by nonstructeral protein 5a of hepatitis C virus]
Hepatitis C
[The effect of Hepatitis C virus nonstructural protein 5A on cell cycling]
Hepatitis C
[Transfection and expression of HCV-NS(5)B gene in Huh-7 cells]
Hepatitis C
[Use of synthetic peptides as additional antigens for detecting antibodies to hepatitis C virus]
Hepatitis C, Chronic
Advances in drug development for hepatitis C.
Hepatitis C, Chronic
Analysis of Naturally Occurring Resistance-Associated Variants to NS3/4A Protein Inhibitors, NS5A Protein Inhibitors, and NS5B Polymerase Inhibitors in Patients With Chronic Hepatitis C.
Hepatitis C, Chronic
Antiviral Effect, Safety, and Pharmacokinetics of Five-Day Oral Administration of Deleobuvir (BI 207127), an Investigational Hepatitis C Virus RNA Polymerase Inhibitor, in Patients with Chronic Hepatitis C.
Hepatitis C, Chronic
Assessment of hepatitis C virus RNA levels by quantitative competitive RNA polymerase chain reaction: high-titer viremia correlates with advanced stage of disease.
Hepatitis C, Chronic
Benefit-risk assessment for sofosbuvir/velpatasvir/voxilaprevir based on patient population and hepatitis C virus genotype: U. S. Food and Drug Administration's evaluation.
Hepatitis C, Chronic
Changing the face of hepatitis C management - the design and development of sofosbuvir.
Hepatitis C, Chronic
Clinical Pharmacokinetics and Pharmacodynamics of Ledipasvir/Sofosbuvir, a Fixed-Dose Combination Tablet for the Treatment of Hepatitis C.
Hepatitis C, Chronic
Daclatasvir combined with sofosbuvir or simeprevir in liver transplant recipients with severe recurrent hepatitis C infection.
Hepatitis C, Chronic
Drug-Drug Interaction Profile of the Fixed-Dose Combination Tablet Regimen Ledipasvir/Sofosbuvir.
Hepatitis C, Chronic
Effect of mutation in the hepatitis C virus nonstructural 5B region on HCV replication.
Hepatitis C, Chronic
Factors predictive of sustained virological response following 72 weeks of combination therapy for genotype 1b hepatitis C.
Hepatitis C, Chronic
Fixed-dose combination of sofosbuvir and ledipasvir for the treatment of chronic hepatitis C genotype 1.
Hepatitis C, Chronic
Glecaprevir/pibrentasvir for the treatment of chronic hepatitis C virus infection in adults.
Hepatitis C, Chronic
GSK2878175, a pan-genotypic non-nucleoside NS5B polymerase inhibitor, in healthy and treatment-naïve chronic hepatitis C subjects.
Hepatitis C, Chronic
HCV replication in PBMC and its influence on interferon therapy.
Hepatitis C, Chronic
Identification of beta-subunit of bacterial RNA-polymerase--a non-species-specific bacterial protein--as target of antibodies in primary biliary cirrhosis.
Hepatitis C, Chronic
Immune response to a hepatitis C virus nonstructural protein in chronic hepatitis C virus infection.
Hepatitis C, Chronic
Mutations in the nonstructural 5A region of hepatitis C virus and response of chronic hepatitis C to interferon alfa.
Hepatitis C, Chronic
Mutations in the nonstructural protein 5A gene and response to interferon in patients with chronic hepatitis C virus 1b infection.
Hepatitis C, Chronic
Mutations in the nonstructural protein 5A gene and response to interferon therapy in young patients with chronic hepatitis C virus 1b infection.
Hepatitis C, Chronic
Naturally occurring mutations associated with resistance to HCV NS5B polymerase and NS3 protease inhibitors in treatment-naïve patients with chronic hepatitis C.
Hepatitis C, Chronic
New Non-Nucleocide NS5B Protein Inhibitors for the Treatment of Chronic Hepatitis C Infection.
Hepatitis C, Chronic
Nonstructural Protein 5A (NS5A) Resistance Profile in Patients with Chronic Hepatitis C Treated with Ledipasvir-Containing Regimens Without Sofosbuvir.
Hepatitis C, Chronic
Ombitasvir/Paritaprevir/Ritonavir Plus Dasabuvir: A Review in Chronic HCV Genotype 1 Infection.
Hepatitis C, Chronic
Pharmacokinetics of hepatitis C virus NS5A inhibitor JNJ-56914845 (GSK2336805) in subjects with hepatic impairment.
Hepatitis C, Chronic
Polymorphisms of NS5B protein relates to early clearance of hepatitis C virus by interferon plus ribavirin: a pilot study.
Hepatitis C, Chronic
Real-world effectiveness and safety of sofosbuvir and nonstructural protein 5A inhibitors for chronic hepatitis C genotype 1, 2, 3, 4, or 6: a multicentre cohort study.
Hepatitis C, Chronic
Retreatment of chronic hepatitis C virus genotype-4 patients after non-structural protein 5A inhibitors' failure: efficacy and safety of different regimens.
Hepatitis C, Chronic
Review article: the efficacy and safety of sofosbuvir, a novel, oral nucleotide NS5B polymerase inhibitor, in the treatment of chronic hepatitis C virus infection.
Hepatitis C, Chronic
Ribavirin mode of action in chronic hepatitis C: from clinical use back to molecular mechanisms.
Hepatitis C, Chronic
SAR study of bisamides as cyclophilin a inhibitors for the development of host-targeting therapy for hepatitis C virus infection.
Hepatitis C, Chronic
Serum hepatitis C virus RNA levels in chronic hepatitis C--importance for outcome of interferon alfa-2b treatment.
Hepatitis C, Chronic
Sofosbuvir/velpatasvir fixed-dose combination for the treatment of chronic hepatitis C virus infection.
Hepatitis C, Chronic
Sofosbuvir: first global approval.
Hepatitis C, Chronic
Synthesis and Anti-HCV Activity of Sugar-Modified Guanosine Analogues: Discovery of AL-611 as an HCV NS5B Polymerase Inhibitor for the Treatment of Chronic Hepatitis C.
Hepatitis C, Chronic
The presence of resistance mutations to protease and polymerase inhibitors in Hepatitis C virus sequences from the Los Alamos databank.
Hepatitis C, Chronic
Therapy of hepatitis C: other options.
Hepatitis C, Chronic
Use and interpretation of HCV diagnostic tests in the clinical setting.
Hepatitis E
A mutation in the hepatitis E virus RNA polymerase promotes its replication and associates with ribavirin treatment failure in organ transplant recipients.
Hepatitis E
A novel mycovirus that is related to the human pathogen hepatitis E virus and rubi-like viruses.
Hepatitis E
Chronic hepatitis E in a heart transplant patient: sofosbuvir and ribavirin regimen not fully effective.
Hepatitis E
Computer-assisted assignment of functional domains in the nonstructural polyprotein of hepatitis E virus: delineation of an additional group of positive-strand RNA plant and animal viruses.
Hepatitis E
Deubiquitination activity associated with hepatitis E virus putative papain-like cysteine protease.
Hepatitis E
Effective inhibition of hepatitis E virus replication in A549 cells and piglets by RNA interference (RNAi) targeting RNA-dependent RNA polymerase.
Hepatitis E
Expression and processing of the Hepatitis E virus ORF1 nonstructural polyprotein.
Hepatitis E
First Crystal Structure of a Nonstructural Hepatitis E Viral Protein Identifies a Putative Novel Zinc-Binding Protein.
Hepatitis E
Hepatitis E virus (HEV): strain variation in the nonstructural gene region encoding consensus motifs for an RNA-dependent RNA polymerase and an ATP/GTP binding site.
Hepatitis E
Hepatitis E virus ORF1 encoded non structural protein-host protein interaction network.
Hepatitis E
Hepatitis E virus RNA dependent RNA polymerase: RNA template specificities, recruitment and synthesis.
Hepatitis E
Hepatitis E Virus RNA-Dependent RNA Polymerase is Involved in RNA Replication and Infectious Particle Production.
Hepatitis E
Human linear B-cell epitopes encoded by the hepatitis E virus include determinants in the RNA-dependent RNA polymerase.
Hepatitis E
Identification and genetic characterization of a porcine hepe-astrovirus (bastrovirus) in the United States.
Hepatitis E
Identification of genetic diversity of hepatitis E virus (HEV) and determination of the seroprevalence of HEV in eastern China.
Hepatitis E
Molecular characterization of a hepatitis E virus isolate from Namibia.
Hepatitis E
Partial sequence comparison of eight new Chinese strains of hepatitis E virus suggests the genome sequence is relatively stable.
Hepatitis E
Phylogenetic analysis of hepatitis E virus isolates from India (1976-1993).
Hepatitis E
Ribavirin for Hepatitis E Virus Infection After Organ Transplantation: A Large European Retrospective Multicenter Study.
Hepatitis E
RNA-dependent RNA Polymerase Assay for Hepatitis E Virus.
Hepatitis E
The 3' end of hepatitis E virus (HEV) genome binds specifically to the viral RNA-dependent RNA polymerase (RdRp).
Hepatitis E
The Lysine Residues within the Human Ribosomal Protein S17 Sequence Naturally Inserted into the Viral Nonstructural Protein of a Unique Strain of Hepatitis E Virus Are Important for Enhanced Virus Replication.
Hepatitis E
Zinc salts block Hepatitis E virus replication by inhibiting the activity of viral RNA-dependent RNA polymerase.
Hepatitis, Autoimmune
Identification of beta-subunit of bacterial RNA-polymerase--a non-species-specific bacterial protein--as target of antibodies in primary biliary cirrhosis.
Hepatitis, Chronic
Construction and characterization of Genotype-3 hepatitis C virus replicon revealed critical genotype-3-specific polymorphism for drug resistance and viral fitness.
Hepatitis, Chronic
Liver histology in anti-HCV-positive persons with normal or minimally elevated aminotransferases.
Hepatitis, Chronic
M2 Macrophages Play Critical Roles in Progression of Inflammatory Liver Disease in Hepatitis C Virus Transgenic Mice.
Hepatitis, Chronic
Ribavirin for Hepatitis E Virus Infection After Organ Transplantation: A Large European Retrospective Multicenter Study.
Herpes Simplex
A combination microbicide gel protects macaques against vaginal simian human immunodeficiency virus-reverse transcriptase infection, but only partially reduces herpes simplex virus-2 infection after a single high-dose cochallenge.
Herpes Simplex
Binding of herpes simplex virus-1 US11 to specific RNA sequences.
Herpes Simplex
Characterization of the herpes simplex virus (HSV)-1 tegument protein VP1-2 during infection with the HSV temperature-sensitive mutant tsB7.
Herpes Simplex
Conserved Outer Tegument Component UL11 from Herpes Simplex Virus 1 Is an Intrinsically Disordered, RNA-Binding Protein.
Herpes Simplex
Distinct domains in herpes simplex virus type 1 US11 protein mediate post-transcriptional transactivation of human T-lymphotropic virus type I envelope glycoprotein gene expression and specific binding to the Rex responsive element.
Herpes Simplex
Emerging antiviral drugs.
Herpes Simplex
Evidence that herpes simplex virus DNA is transcribed by cellular RNA polymerase B.
Herpes Simplex
Herpes simplex virus 1 RNA-binding protein US11 negatively regulates the accumulation of a truncated viral mRNA.
Herpes Simplex
Identification of an export control sequence and a requirement for the KH domains in ICP27 from herpes simplex virus type 1.
Herpes Simplex
In vitro transcription of herpes simplex virus ANG DNA by E-coli RNA polymerase.
Herpes Simplex
In vitro transcription of herpes simplex virus genes. Partial purification and properties of RNA polymerase II from uninfected and infected Hep-2 cells.
Herpes Simplex
Inhibition of hepatitis B virus DNA polymerase by enantiomers of penciclovir triphosphate and metabolic basis for selective inhibition of HBV replication by penciclovir.
Herpes Simplex
Intercellular trafficking activity of herpes simplex virus US11 gene product in the mouse brain.
Herpes Simplex
Nucleotide sequence of a 55 kbp region from the right end of the genome of a pathogenic African swine fever virus isolate (Malawi LIL20/1).
Herpes Simplex
Release of RNA polymerase from vero cell mitochondria after herpes simplex virus type 1 infection.
Herpes Simplex
RNA polymerase III and antiviral innate immune response.
Herpes Simplex
Structure and function in the herpes simplex virus 1 RNA-binding protein U(s)11: mapping of the domain required for ribosomal and nucleolar association and RNA binding in vitro.
Herpes Simplex
Suppression of PACT-induced type I interferon production by herpes simplex virus type 1 Us11 protein.
Herpes Simplex
The antiviral activity of tetrazole phosphonic acids and their analogues.
Herpes Simplex
The Epstein-Barr virus SM protein is functionally similar to ICP27 from herpes simplex virus in viral infections.
Herpes Simplex
The herpes simplex virus UL37 protein is phosphorylated in infected cells.
Herpes Simplex
The herpes simplex virus Us11 open reading frame encodes a sequence-specific RNA-binding protein.
Herpes Simplex
Variation of DNA polymerase and RNA polymerase activities in cells infected with herpes simplex virus type 1.
Herpes Zoster
RNA polymerase III and antiviral innate immune response.
Herpesviridae Infections
Approved Antiviral Drugs over the Past 50 Years.
Histiocytosis
The Expression of Insulin-Like Growth Factor 2 Messenger RNA-Binding Protein 3 in Langerhans Cell Histiocytosis and Langerhans Cell Sarcoma.
Histiocytosis, Langerhans-Cell
The Expression of Insulin-Like Growth Factor 2 Messenger RNA-Binding Protein 3 in Langerhans Cell Histiocytosis and Langerhans Cell Sarcoma.
HIV Infections
Acute HIV Infection in Youth: Protocol for the Adolescent Trials Network 147 (ATN147) Comprehensive Adolescent Research and Engagement Studies (CARES) Study.
HIV Infections
Approved Antiviral Drugs over the Past 50 Years.
HIV Infections
Clinical Versus Rapid Molecular HIV Diagnosis in Hospitalized African Infants: A Randomized Controlled Trial Simulating Point-of-Care Infant Testing.
HIV Infections
Column selection and method development for the determination of the enantiomeric purity of investigational non-nucleoside reverse transcriptase inhibitors.
HIV Infections
Efavirenz or nevirapine in three-drug combination therapy with two nucleoside or nucleotide-reverse transcriptase inhibitors for initial treatment of HIV infection in antiretroviral-naïve individuals.
HIV Infections
Efavirenz or nevirapine in three-drug combination therapy with two nucleoside-reverse transcriptase inhibitors for initial treatment of HIV infection in antiretroviral-naïve individuals.
HIV Infections
Emerging antiviral drugs.
HIV Infections
Estimation of the timing of perinatal transmission of HIV.
HIV Infections
Highlights in the development of new antiviral agents.
HIV Infections
Impact of protease inhibitor therapy on HIV-related oropharyngeal candidiasis.
HIV Infections
[Clinical indications for resistance testing HIV infection].
HIV Infections
[Drug clinics. How I treat HIV infections. II. Nucleoside reverse transcriptase inhibitors]
HIV Infections
[Pharma-clinics. How I treat ... HIV infection. III. Non-nucleoside reverse transcriptase inhibitors]
HIV Infections
[Treatment of HIV infection in clinical practice. Wide-range genotypic resistance to all nucleoside analogues and protease inhibitors, and severe intolerance to all non-nucleoside inhibitors of inverse transcriptase]
HIV Seropositivity
Acute HIV Infections among Men with Genital Ulcer Disease in South Africa.
Huntington Disease
FUS/TLS as a polyglutamine aggregate interacting protein.
Huntington Disease
Pathogenic SREK1 decrease in Huntington's disease lowers TAF1 mimicking X-linked dystonia parkinsonism.
Huntington Disease
RNA-binding protein TLS is a major nuclear aggregate-interacting protein in huntingtin exon 1 with expanded polyglutamine-expressing cells.
Huntington Disease
The RNA-binding protein FUS/TLS is a common aggregate-interacting protein in polyglutamine diseases.
Hyperalgesia
Silencing of the RNA-binding protein HuR attenuates hyperalgesia and motor disability in experimental autoimmune encephalomyelitis.
Hyperlipidemias
[Hyperlipidemia and glucose intolerance in patients with HIV infection receiving antiretroviral therapy]
Hyperparathyroidism
Loss of expression for the Wnt pathway components adenomatous polyposis coli and glycogen synthase kinase 3-beta in parathyroid carcinomas.
Hypersensitivity
A Screen for rfaH Suppressors Reveals a Key Role for a Connector Region of Termination Factor Rho.
Hypersensitivity
Expression in cattle of epitopes of a heterologous virus using a recombinant rinderpest virus.
Hypersensitivity
Functions that protect Escherichia coli from DNA-protein crosslinks.
Hypersensitivity
Insights into how innocuous foods or proteins deserving of immune ignorance can become allergens.
Hypersensitivity
Integration host factor activates the Ner-repressed early promoter of transposable Mu-like phage D108.
Hypersensitivity
Mitochondrial RNA polymerase of Saccharomyces cerevisiae: composition and mechanism of promoter recognition.
Hypersensitivity
Mutations in the ss subunit of the Bacillus subtilis RNA polymerase that confer both rifampicin resistance and hypersensitivity to NusG.
Hypersensitivity
Passage of RNA polymerase from open complex to elongation mode at the Escherichia coli lacUV5 promoter: nucleolytic hypersensitivity as a probe for complex conformational changes.
Hypersensitivity
Separate mechanisms are involved in rifampicin upmodulated and downmodulated gene expression in Salmonella Typhimurium.
Hypersensitivity
Spinal RyR2 pathway regulated by the RNA-binding protein HuD induces pain hypersensitivity in antiretroviral neuropathy.
Hypersensitivity
Systematic enrichment analysis of potentially functional regions for 103 prostate cancer risk-associated loci.
Hypersensitivity
[Correlation, in previously treated HIV-1 positive patients, between hypersensitivity reaction to abacavir and the presence of the HLA-B*5701 allele.]
Hypertension
Deficiency of cold-inducible RNA-binding protein exacerbated monocrotaline-induced pulmonary artery hypertension through Caveolin1 and CAVIN1.
Hypertension
The Role of PB1 Domain Proteins in Endothelial Cell Dysfunction and Disease.
Hypertension, Portal
Non-cirrhotic portal hypertension in HIV mono-infected patients.
Hyperthyroidism
Triiodothyronine effects on RNA polymerase activities in isolated neuronal and glial nuclei of the mature rat brain cortex.
Hypogonadism
Endocrine Aspects of 4H Leukodystrophy: A Case Report and Review of the Literature.
Hyponatremia
Incidence and predictive factors of transaminase elevation in patients consulting for dengue fever in Cayenne Hospital, French Guiana.
Hypothyroidism
Mitochondrial DNA, RNA and protein synthesis in normal and hypothyroid developing rat liver.
Idiopathic Interstitial Pneumonias
The long-term outcome of interstitial lung disease with anti-aminoacyl-tRNA synthetase antibodies.
Idiopathic Pulmonary Fibrosis
Clinical Significance of Cold-Inducible RNA-Binding Protein in Idiopathic Pulmonary Fibrosis.
Immune Reconstitution Inflammatory Syndrome
Cutaneous toxicities of antiretroviral therapy for HIV: part II. Nonnucleoside reverse transcriptase inhibitors, entry and fusion inhibitors, integrase inhibitors, and immune reconstitution syndrome.
Infections
'Drc', a structurally novel ssDNA-binding transcription regulator of N4-related bacterial viruses.
Infections
1918 HA and the viral RNA polymerase complex enhance viral pathogenicity, but only HA induces aberrant host responses in mice.
Infections
?, a new subunit of RNA polymerase found in gram-positive bacteria.
Infections
A Bunyavirus-Inducible Ubiquitin Ligase Targets RNA Polymerase IV for Degradation during Viral Pathogenesis in Rice.
Infections
A combination microbicide gel protects macaques against vaginal simian human immunodeficiency virus-reverse transcriptase infection, but only partially reduces herpes simplex virus-2 infection after a single high-dose cochallenge.
Infections
A fatal case report of antibody-dependent enhancement of dengue virus type 1 following remote Zika virus infection.
Infections
A genome-linked copy of the NS-1 polypeptide is located on the outside of infectious parvovirus particles.
Infections
A high-throughput assay using dengue-1 virus-like particles for drug discovery.
Infections
A natural variant of a host RNA-dependent RNA polymerase is associated with increased susceptibility to viruses by Nicotiana benthamiana.
Infections
A necrosis-inducing elicitor domain encoded by both symptomatic and asymptomatic Plantago asiatica mosaic virus isolates, whose expression is modulated by virus replication.
Infections
A non-canonical multisubunit RNA polymerase encoded by a giant bacteriophage.
Infections
A novel bi-functional DNA vaccine expressing VP1 protein and producing antisense RNA targeted to 5'UTR of foot-and-mouth disease virus can induce both rapid inhibitory effect and specific immune response in mice.
Infections
A novel type of paramyxovirus found in Hungary in a masked water snake (Homalopsis buccata) with pneumonia supports the suggested new taxonomy within the Ferlavirus genus.
Infections
A phase 3b study of sofosbuvir plus ribavirin in Taiwanese patients with chronic genotype 2 hepatitis C virus infection.
Infections
A promising antiviral candidate drug for the COVID-19 pandemic: A mini-review of remdesivir.
Infections
A quantitative high-resolution genetic profile rapidly identifies sequence determinants of hepatitis C viral fitness and drug sensitivity.
Infections
A retrospective case-control study of hepatitis C virus infection and oral lichen planus in Japan: association study with mutations in the core and NS5A region of hepatitis C virus.
Infections
A Scoping Insight on Potential Prophylactics, Vaccines and Therapeutic Weaponry for the Ongoing Novel Coronavirus (COVID-19) Pandemic- A Comprehensive Review.
Infections
A shift in plant proteome profile for a Bromodomain containing RNA binding Protein (BRP1) in plants infected with Cucumber mosaic virus and its satellite RNA.
Infections
A simple cell-based high throughput screening (HTS) assay for inhibitors of Salmonella enterica RNA polymerase containing the general stress response regulator RpoS (?S).
Infections
A simple method of distinguishing the bacterial viruses T3 and T7, and a critical reevaluation of their heterologous and homologous exclusion.
Infections
A Single ssRNA Segment Encoding RdRp Is Sufficient for Replication, Infection, and Transmission of Ourmia-Like Virus in Fungi.
Infections
A transmissible human endogenous retrovirus.
Infections
A validated LC-MS/MS method for the simultaneous determination of BMS-791325, a hepatitis C virus NS5B RNA polymerase inhibitor, and its metabolite in plasma.
Infections
A25?Phylogenetic analysis of the nucleocapsid and RNA-dependent RNA polymerase fragments of the first imported case of middle east respiratory syndrome coronavirus (MERS-CoV) infection in the Philippines from Saudi Arabia, February 2015.
Infections
Abortive infection of a rabbit cornea cell line by vesicular stomatitis virus: conversion to productive infection by superinfection with vaccinia virus.
Infections
Absence of a gene dosage effect during bacteriophage T3- and T7-coded RNA polymerase synthesis.
Infections
Accumulation of 24 nucleotide transgene-derived siRNAs is associated with crinivirus immunity in transgenic plants.
Infections
Accurate serodiagnosis of B19 parvovirus infections by measurement of IgG avidity.
Infections
Activation of Tomato bushy stunt virus RdRp by cellular Hsp70 is enhanced by phospholipids in vitro.
Infections
Acute hepatitis E infection associated with a false-positive serology against Epstein-Barr virus.
Infections
Adenovirus VAI RNA antagonizes the antiviral action of interferon by preventing activation of the interferon-induced eIF-2 alpha kinase.
Infections
Adenovirus VAI RNA prevents phosphorylation of the eukaryotic initiation factor 2 alpha subunit subsequent to infection.
Infections
Advances in drug development for hepatitis C.
Infections
An adenovirus mutant unable to express VAI RNA displays different growth responses and sensitivity to interferon in various host cell lines.
Infections
An attenuating mutation in nsP1 of the Sindbis-group virus S.A.AR86 accelerates nonstructural protein processing and up-regulates viral 26S RNA synthesis.
Infections
An E. coli B mutation, rpoB5081, that prevents growth of phage T4 strains defective in host DNA degradation.
Infections
An interferon-free antiviral regimen for HCV after liver transplantation.
Infections
An RNA polymerase II transcription factor inactivated in poliovirus-infected cells copurifies with transcription factor TFIID.
Infections
Analysis of Dengue Virus Genetic Diversity during Human and Mosquito Infection Reveals Genetic Constraints.
Infections
Analysis of mutant NS5B proteins encoded by isolates from chimpanzees chronically infected following clonal HCV RNA inoculation.
Infections
Andrographolide binds to spike glycoprotein and RNA-dependent RNA polymerase (NSP12) of SARS-CoV-2 by in silico approach: a probable molecule in the development of anti-coronaviral drug.
Infections
Anti-TMV activity and functional mechanisms of two sesquiterpenoids isolated from Tithonia diversifolia.
Infections
Anti-viral mechanism of barramundi Mx against betanodavirus involves the inhibition of viral RNA synthesis through the interference of RdRp.
Infections
Antibodies against West Nile Virus nonstructural protein NS1 prevent lethal infection through Fc gamma receptor-dependent and -independent mechanisms.
Infections
Antibodies to foot-and-mouth disease virus infection associated (VIA) antigen: use of a bioengineered VIA protein as antigen in an ELISA.
Infections
Antibodies to the nonstructural protein of parvovirus B19 in persistently infected patients: implications for pathogenesis.
Infections
Antibodies to the Novel Human Pegivirus 2 Are Associated with Active and Resolved Infections.
Infections
Antibody to the nonstructural protein NS1 of Japanese encephalitis virus: potential application of mAb-based indirect ELISA to differentiate infection from vaccination.
Infections
Antiviral action of nitric oxide on dengue virus type 2 replication.
Infections
Antiviral Effects of a Transgenic RNA-Dependent RNA-Polymerase.
Infections
Antiviral Protection via RdRP-Mediated Stable Activation of Innate Immunity.
Infections
Antiviral treatment of hepatitis C: present status and future prospects.
Infections
ANXA2 Facilitates Enterovirus 71 Infection by Interacting with 3D Polymerase and PI4KB to Assist the Assembly of Replication Organelles.
Infections
Apoptosis of liver-derived cells induced by parvovirus B19 nonstructural protein.
Infections
Approved Antiviral Drugs over the Past 50 Years.
Infections
Arabidopsis RNA Polymerase V Mediates Enhanced Compaction and Silencing of Geminivirus and Transposon Chromatin during Host Recovery from Infection.
Infections
Assembly of Bacillus subtilis phage phe29. 2. Mutants in the cistrons coding for the non-structural proteins.
Infections
Assembly of viroplasms by viral nonstructural protein Pns9 is essential for persistent infection of rice gall dwarf virus in its insect vector.
Infections
Assessment of Sep1virus interaction with stationary cultures by transcriptional and flow cytometry studies.
Infections
Autophagy enhances the replication of classical swine fever virus in vitro.
Infections
Autophagy protein ATG5 interacts transiently with the hepatitis C virus RNA polymerase (NS5B) early during infection.
Infections
Avian reovirus major mu-class outer capsid protein influences efficiency of productive macrophage infection in a virus strain-specific manner.
Infections
B-cell responses during primary and secondary dengue virus infections in humans.
Infections
B19 parvovirus.
Infections
Bacteriophage SP6-specific RNA polymerase. I. Isolation and characterization of the enzyme.
Infections
Baculovirus late expression factors.
Infections
Baculovirus-expressed nonstructural protein NS2 of bluetongue virus induces a cytotoxic T-cell response in mice which affords partial protection.
Infections
Benefit-risk assessment for sofosbuvir/velpatasvir/voxilaprevir based on patient population and hepatitis C virus genotype: U. S. Food and Drug Administration's evaluation.
Infections
Binding of the bacteriophage T4 transcriptional activator, MotA, to T4 middle promoter DNA: evidence for both major and minor groove contacts.
Infections
Biochemical activities of minute virus of mice nonstructural protein NS1 are modulated In vitro by the phosphorylation state of the polypeptide.
Infections
BKV and JCV large T antigen-specific CD8+ T cell response in HLA A*0201+ kidney transplant recipients with polyomavirus nephropathy and patients with progressive multifocal leukoencephalopathy.
Infections
Blocking of interferon-induced Jak-Stat signaling by Japanese encephalitis virus NS5 through a protein tyrosine phosphatase-mediated mechanism.
Infections
Bombyx mori nucleopolyhedrovirus lef8 gene: effects of deletion and implications for gene transduction applications.
Infections
Borrelia burgdorferi erpT expression in the arthropod vector and murine host.
Infections
BPR-3P0128 inhibits RNA-dependent RNA polymerase elongation and VPg uridylylation activities of Enterovirus 71.
Infections
Cardiovirus 2A protein associates with 40S but not 80S ribosome subunits during infection.
Infections
Cascade regulation of vaccinia virus gene expression is modulated by multistage promoters.
Infections
Cathelicidin antimicrobial peptides suppress EV71 infection via regulating antiviral response and inhibiting viral binding.
Infections
Cellular vimentin regulates construction of dengue virus replication complexes through interaction with NS4A protein.
Infections
Chagas Disease in Southern Coastal Ecuador: Coinfections with Arboviruses and a Comparison of Serological Assays for Chagas Disease Diagnosis.
Infections
Changes in the proteome of pad2-1, a glutathione depleted Arabidopsis mutant, during Pseudomonas syringae infection.
Infections
Characteristics of human infection with avian influenza viruses and development of new antiviral agents.
Infections
Characteristics of siRNAs derived from Southern rice black-streaked dwarf virus in infected rice and their potential role in host gene regulation.
Infections
Characterization of a 7-kilodalton subunit of vaccinia virus DNA-dependent RNA polymerase with structural similarities to the smallest subunit of eukaryotic RNA polymerase II.
Infections
Characterization of a monoclonal antibody against the 3D polymerase of enterovirus 71 and its use for the detection of human enterovirus A infection.
Infections
Characterization of a Sugar-O-methyltransferase TiaS5 Affords New Tiacumicin Analogues with Improved Antibacterial Properties and Reveals Substrate Promiscuity.
Infections
Characterization of an enteropathogenic bovine calicivirus representing a potentially new calicivirus genus.
Infections
Characterization of In vitro inhibitory effects of consensus short interference RNAs against non-structural 5B gene of hepatitis C virus 1a genotype.
Infections
Characterization of pre-transcription complexes made at a bacteriophage T4 middle promoter: involvement of the T4 MotA activator and the T4 AsiA protein, a sigma 70 binding protein, in the formation of the open complex.
Infections
Characterization of Resistance to the Nonnucleoside NS5B Inhibitor Filibuvir in Hepatitis C Virus-Infected Patients.
Infections
Characterization of the infectivity of Bamboo mosaic virus with its correlation to the in vitro replicase activities in Nicotiana benthamiana.
Infections
Characterization of the interaction between the influenza A virus polymerase subunit PB1 and the host nuclear import factor Ran-binding protein 5.
Infections
Characterization of tubular structures composed of nonstructural protein NS1 of African horsesickness virus expressed in insect cells.
Infections
Characterization of two RNA polymerase activities induced by mouse hepatitis virus.
Infections
Chronic hepatitis E in a heart transplant patient: sofosbuvir and ribavirin regimen not fully effective.
Infections
Chutes and ladders in hepatitis C nucleoside drug development.
Infections
Citrus tristeza virus co-opts glyceraldehyde 3-phosphate dehydrogenase for its infectious cycle by interacting with the viral-encoded protein p23.
Infections
Citrus tristeza virus: Host RNA Silencing and Virus Counteraction.
Infections
Clinical and Laboratory Diagnosis of Dengue Virus Infection.
Infections
Clinical diagnosis of early dengue infection by novel one-step multiplex real-time RT-PCR targeting NS1 gene.
Infections
Clinical Pharmacokinetics of Ombitasvir.
Infections
CNOT4-Mediated Ubiquitination of Influenza A Virus Nucleoprotein Promotes Viral RNA Replication.
Infections
Coexistence of multiple coronaviruses in several bat colonies in an abandoned mineshaft.
Infections
Combination of Nonstructural Protein 1-Based Enzyme-Linked Immunosorbent Assays Can Detect and Distinguish Various Dengue Virus and Zika Virus Infections.
Infections
Combination of pharmacophore hypothesis and molecular docking to identify novel inhibitors of HCV NS5B polymerase.
Infections
Comparative Evaluation of Tears and Nasopharyngeal Swab for SARS-CoV-2 in COVID-19 Dedicated Intensive Care Unit Patients.
Infections
Comparison of turnip crinkle virus RNA-dependent RNA polymerase preparations expressed in Escherichia coli or derived from infected plants.
Infections
Comparison of two commercially available dengue virus (DENV) NS1 capture enzyme-linked immunosorbent assays using a single clinical sample for diagnosis of acute DENV infection.
Infections
Compensatory mutations restore the replication defects caused by cytotoxic T lymphocyte escape mutations in hepatitis C virus polymerase.
Infections
Competition between wild-type virus and a reassortant from subgroups I and II of CMV and activation of antiviral responses in cowpea.
Infections
Comprehensive analysis of full genome sequence and Bd-milRNA/target mRNAs to discover the mechanism of hypovirulence in Botryosphaeria dothidea strains on pear infection with BdCV1 and BdPV1.
Infections
Comprehensive mapping of common immunodominant epitopes in the west nile virus nonstructural protein 1 recognized by avian antibody responses.
Infections
Concomitant proton pump inhibitor use does not reduce the efficacy of elbasvir/grazoprevir: A pooled analysis of 1,322 patients with hepatitis C infection.
Infections
Consensus numbering system for the rifampicin resistance-associated rpoB gene mutations in pathogenic mycobacteria.
Infections
Construction of gag-chimeric viruses between HIV-1 and SIVmac that are capable of productive multi-cycle infection.
Infections
Control of gene transcription in T-even bacteriophages: alterations in RNA polymerase accompanying phage infection.
Infections
Conversion of Bacillus subtilis RNA polymerase activity in vitro by a protein induced by phage SP01.
Infections
Cooperative effect of the attenuation determinants derived from poliovirus sabin 1 strain is essential for attenuation of enterovirus 71 in the NOD/SCID mouse infection model.
Infections
Core RNA Interference Genes Involved in miRNA and Ta-siRNA Biogenesis in Hops and Their Expression Analysis after Challenging with Verticillium nonalfalfae.
Infections
Coronavirus Endoribonuclease and Deubiquitinating Interferon Antagonists Differentially Modulate the Host Response during Replication in Macrophages.
Infections
Coronavirus nonstructural protein 1: Common and distinct functions in the regulation of host and viral gene expression.
Infections
Correlation between chlamydial infection and autoimmune response: molecular mimicry between RNA polymerase major sigma subunit from Chlamydia trachomatis and human L7.
Infections
Correlation of cytokine level with the severity of severe fever with thrombocytopenia syndrome.
Infections
Corynebacterium tuberculostearicum, a human skin colonizer, induces the canonical nuclear factor-?B inflammatory signaling pathway in human skin cells.
Infections
COVID-19: An Update on Pathogenesis and Treatment.
Infections
Coxsackie B virus infection of mice: inoculation by the oral route protects the pancreas from damage, but not from infection.
Infections
Critical phosphoprotein elements that regulate polymerase architecture and function in vesicular stomatitis virus.
Infections
Currently circulating genotypes of hepatitis E virus in India, 2014-2018.
Infections
Currently Circulating Genotypes of Hepatitis E Virus in India, 2014-2018.
Infections
CVB3 Nonstructural 2A Protein Modulates SREBP1a Signaling via the MEK/ERK Pathway.
Infections
Daclatasvir + asunaprevir + beclabuvir ± ribavirin for chronic HCV genotype 1-infected treatment-naive patients.
Infections
Daclatasvir combined with sofosbuvir or simeprevir in liver transplant recipients with severe recurrent hepatitis C infection.
Infections
De novo generation of defective interfering-like RNAs in broad bean mottle bromovirus.
Infections
De novo synthesis of N and P proteins as a key step in Sendai virus gene expression.
Infections
Defining the Utility of a Commercial NS1 Antigen Capture Kit as a Dengue Virus (DENV) Diagnostic Tool.
Infections
Dengue fever during pregnancy.
Infections
Dengue nonstructural protein 1 antigen in the urine as a rapid and convenient diagnostic test during the febrile stage in patients with dengue infection.
Infections
Dengue Nonstructural Protein 1 Maintains Autophagy through Retarding Caspase-Mediated Cleavage of Beclin-1.
Infections
Dengue virus non-structural protein 1: a pathogenic factor, therapeutic target, and vaccine candidate.
Infections
Dengue virus nonstructural protein NS5 induces interleukin-8 transcription and secretion.
Infections
Dengue virus NS1 triggers endothelial permeability and vascular leak that is prevented by NS1 vaccination.
Infections
Dengue Virus Perturbs Mitochondrial Morphodynamics to Dampen Innate Immune Responses.
Infections
Denovo designing, retro-combinatorial synthesis, and molecular dynamics analysis identify novel antiviral VTRM1.1 against RNA-dependent RNA polymerase of SARS CoV2 virus.
Infections
Design and evaluation of novel tetracyclic benzofurans as palm site allosteric inhibitors of HCV NS5B polymerase.
Infections
Designing an effective therapeutic siRNA to silence RdRp gene of SARS-CoV-2.
Infections
Detailed phenotypic characterization of five temperature-sensitive mutants in the 22- and 147-kilodalton subunits of vaccinia virus DNA-dependent RNA polymerase.
Infections
Detection of a subunit of cellular Pol II within highly purified preparations of RNA polymerase isolated from rabbit poxvirus virions.
Infections
Detection of dengue virus nonstructural protein 1 (NS1) by using ELISA as a useful laboratory diagnostic method for dengue virus infection of international travelers.
Infections
Detection of enteroviral infection in paraffin-embedded tissue by the RNA polymerase chain reaction technique.
Infections
Detection of HCV genome in peripheral blood mononuclear cells of Iranian seropositive and HCV RNA negative in plasma of patients with beta-thalassemia major: Occult HCV infection.
Infections
Detection of hepatitis C virus NS5 protein and genome in Chinese carcinoma of the extrahepatic bile duct and its significance.
Infections
Detection of the dengue virus NS1 antigen using an enzyme immunoassay.
Infections
Detection, identification, and differentiation of sheep pox virus and goat pox virus from clinical cases in Giza Governorate, Egypt.
Infections
Determination of the interactome of non-structural protein12 from highly pathogenic porcine reproductive and respiratory syndrome virus with host cellular proteins using high throughput proteomics and identification of HSP70 as a cellular factor for virus replication.
Infections
Development of a CRISPR/Cas9 system against ruminant animal brucellosis.
Infections
Development of an antigen capture immunoassay based on monoclonal antibodies specific for dengue virus serotype 2 nonstructural protein 1 for early and rapid identification of dengue virus serotype 2 infections.
Infections
Development of antibodies to the nonstructural protein NS1 of parvovirus B19 during acute symptomatic and subclinical infection in pregnancy: implications for pathogenesis doubtful.
Infections
Development of giant bacteriophage ?KZ is independent of the host transcription apparatus.
Infections
Diagnosis of persistent aphthovirus infection and its differentiation from vaccination response in cattle by use of enzyme-linked immunoelectrotransfer blot analysis with bioengineered nonstructural viral antigens.
Infections
Diagnosis of Zika virus infection on a nanotechnology platform.
Infections
Dicer-2- and Piwi-mediated RNA interference in Rift Valley fever virus-infected mosquito cells.
Infections
Difference in susceptibility to MxA protein between a coxsackievirus B1 isolate and prototype, impact of serial cell culture passage.
Infections
Differential inductions of RNA silencing among encapsidated double-stranded RNA mycoviruses in the white root rot fungus, Rosellinia necatrix.
Infections
Direct detection of circulating hepatitis C virus RNA using probes from the 5' untranslated region.
Infections
Disassociation of sigma subunit from RNA polymerase of Xanthomonas oryzae pv. oryzae by phage Xp10 infection.
Infections
Discovery of Novel HCV NS5B polymerase inhibitor, 2-(3,4-dimethyl-5,5-dioxidobenzo[e]pyrazolo[4,3-c][1,2]thiazin-2(4H)-yl)-N-(2-fluorobenzyl)acetamide via molecular docking and experimental approach.
Infections
Discovery of novel Hepatitis C virus inhibitor targeting multiple allosteric sites of NS5B polymerase.
Infections
Discovery of Novel Hepatitis C Virus NS5B Polymerase Inhibitors by Combining Random Forest, Multiple e-Pharmacophore Modeling and Docking.
Infections
Discovery of Ubonodin, an Antimicrobial Lasso Peptide Active against Members of the Burkholderia cepacia Complex.
Infections
Distinguishing Secondary Dengue Virus Infection From Zika Virus Infection With Previous Dengue by a Combination of 3 Simple Serological Tests.
Infections
Diversity of the hepatitis C virus NS5B gene during HIV co-infection.
Infections
DNA immunization with Japanese encephalitis virus nonstructural protein NS1 elicits protective immunity in mice.
Infections
DNA-dependent RNA polymerase subunits encoded within the vaccinia virus genome.
Infections
DnaJ homolog Hdj2 facilitates Japanese encephalitis virus replication.
Infections
Downregulation of miR-155-5p facilitates enterovirus 71 replication through suppression of type I IFN response by targeting FOXO3/IRF7 pathway.
Infections
Drug Resistance and HCV Coinfection in Former Blood Donors Infected with HIV Type 1 in China.
Infections
Dutrebis (lamivudine and raltegravir) for use in combination with other antiretroviral products for the treatment of HIV-1 infection.
Infections
Dynamics of viral RNA synthesis during measles virus infection.
Infections
Dynamics on multiple timescales in the RNA-directed RNA polymerase from the cystovirus {phi}6.
Infections
E2 ubiquitin-conjugating enzyme UBE2L6 promotes Senecavirus A proliferation by stabilizing the viral RNA polymerase.
Infections
Early RNAs in SP82- and SP01-infected Bacillus subtilis may be processed.
Infections
Effective inhibition of porcine transmissible gastroenteritis virus replication in ST cells by shRNAs targeting RNA-dependent RNA polymerase gene.
Infections
Effectiveness and safety of sofosbuvir plus ribavirin for HCV genotype 2 patients 65 and over with or without cirrhosis.
Infections
Effects of the RNA-binding protein, KSRP, on innate immune response against Helicobacter pylori infection in mice.
Infections
Efficacy and safety of a two-drug direct-acting antiviral agent regimen ruzasvir 180 mg and uprifosbuvir 450 mg for 12 weeks in adults with chronic hepatitis C virus genotype 1, 2, 3, 4, 5 or 6.
Infections
Efficacy and safety of sofosbuvir-based therapy for the treatment of chronic hepatitis C in treatment-naïve and treatment-experienced patients.
Infections
Efficient In Silico Assay of Inhibitors of Hepatitis C Virus RNA-Dependent RNA Polymerase by Structure-Based Virtual Screening and In Vitro Evaluation.
Infections
Efficient inhibition of Escherichia coli RNA polymerase by the bacteriophage T4 AsiA protein requires that AsiA binds first to free sigma70.
Infections
Electrical detection of dengue biomarker using egg yolk immunoglobulin as the biological recognition element.
Infections
Emerging antiviral drugs.
Infections
Encephalomyocarditis virus (EMCV) proteins 2A and 3BCD localize to nuclei and inhibit cellular mRNA transcription but not rRNA transcription.
Infections
Encephalomyocarditis virus 2A protein is required for viral pathogenesis and inhibition of apoptosis.
Infections
Encephalomyocarditis virus disrupts stress granules, the critical platform for triggering antiviral innate immune responses.
Infections
Endogenous grouper and barramundi Mx proteins facilitated the clearance of betanodavirus RNA-dependent RNA polymerase.
Infections
Engineering partial resistance to cucumber mosaic virus in tobacco using intrabodies specific for the viral polymerase.
Infections
Enhanced cytoplasmic sequestration of the nuclear export receptor CRM1 by NS2 mutations developed in the host regulates parvovirus fitness.
Infections
Epitope-blocking enzyme-linked immunosorbent assay to differentiate west nile virus from Japanese encephalitis virus infections in equine sera.
Infections
Escherichia coli mutant which restricts T7 bacteriophage has an altered RNA polymerase.
Infections
Escherichia coli single-stranded DNA-binding protein is a supercoiled template-dependent transcriptional activator of N4 virion RNA polymerase.
Infections
Establishment and characterization of a brain cell line from sea perch, Lateolabrax japonicus.
Infections
Ethanolic Extract of Melia Fructus Has Anti-influenza A Virus Activity by Affecting Viral Entry and Viral RNA Polymerase.
Infections
Evaluation and Clinical Validation of Two Field-Deployable Reverse Transcription-Insulated Isothermal PCR Assays for the Detection of the Middle East Respiratory Syndrome Coronavirus.
Infections
Evaluation of dengue nonstructural protein 1 antigen strip for the rapid diagnosis of patients with dengue infection.
Infections
Evaluation of serum antibody responses against the rotavirus nonstructural protein NSP4 in children after rhesus rotavirus tetravalent vaccination or natural infection.
Infections
Evaluation of sofosbuvir activity and resistance profile against West Nile virus in vitro.
Infections
Evasion of cellular antiviral responses by human cytomegalovirus TRS1 and IRS1.
Infections
Evidence for direct involvement of T7 RNA polymerase bacteriophage DNA replication.
Infections
Evidence incriminating midges (Diptera: Ceratopogonidae) as potential vectors of Leishmania in Australia.
Infections
Evidence of RNA in D loops of intracellular lambda DNA.
Infections
Evidence of VP1 of duck hepatitis A type 1 virus as a target of neutralizing antibodies and involving receptor-binding activity.
Infections
Evidence that herpes simplex virus DNA is transcribed by cellular RNA polymerase B.
Infections
Exploratory study of oral combination antiviral therapy for hepatitis C.
Infections
Expression in cattle of epitopes of a heterologous virus using a recombinant rinderpest virus.
Infections
Expression of a full-length nonstructural protein NS1 of bluetongue virus serotype 17 in Escherichia coli.
Infections
Expression of dengue virus structural proteins and nonstructural protein NS1 by a recombinant vaccinia virus.
Infections
Expression of the nonstructural protein NS1 of equine influenza A virus: detection of anti-NS1 antibody in post infection equine sera.
Infections
Expression of VP1 protein in the milk of transgenic mice: a potential oral vaccine protects against enterovirus 71 infection.
Infections
Factors affecting de novo RNA synthesis and back-priming by the respiratory syncytial virus polymerase.
Infections
Factors Contributing to the Antiviral Effectiveness of Tenofovir.
Infections
Fidaxomicin: Difimicin; Lipiarmycin; OPT 80; OPT-80; PAR 101; PAR-101.
Infections
Filibuvir, a non-nucleoside NS5B polymerase inhibitor for the potential oral treatment of chronic HCV infection.
Infections
First Crystal Structure of a Nonstructural Hepatitis E Viral Protein Identifies a Putative Novel Zinc-Binding Protein.
Infections
First Report of Bean common mosaic virus Infecting Mungbean (Vigna radiata) in China.
Infections
First report of cucurbit chlorotic yellows virus in association with other whitefly-transmitted viruses in squash (Cucurbita pepo) in Georgia.
Infections
Fish DDX3X exerts antiviral function against grouper nervous necrosis virus infection.
Infections
Fitness Cost of Rifampin Resistance in Neisseria meningitidis: In Vitro Study of Mechanisms Associated with rpoB H553Y Mutation.
Infections
Flavivirus Nonstructural Protein NS5 Dysregulates HSP90 to Broadly Inhibit JAK/STAT Signaling.
Infections
Flavonoids from Pterogyne nitens Inhibit Hepatitis C Virus Entry.
Infections
Frequency of occurrence of HIV-1 dual infection in a Belgian MSM population.
Infections
Full shut-off of Escherichia coli RNA-polymerase by T7 phage requires a small phage-encoded DNA-binding protein.
Infections
Functional analysis of a cellular microRNA in insect host-ascovirus interaction.
Infections
Functional characterization of tumor necrosis factor receptor-associated factor 3 of sea perch (Lateolabrax japonicas) in innate immune.
Infections
Functional organization of cytoplasmic inclusion bodies in cells infected by respiratory syncytial virus.
Infections
Genetic diversity among pandemic 2009 influenza viruses isolated from a transmission chain.
Infections
Genetic Risk Factors for the Development of COVID-19 Coronavirus Infection.
Infections
Genetic variation and recombination of RdRp and HSP 70h genes of Citrus tristeza virus isolates from orange trees showing symptoms of citrus sudden death disease.
Infections
Genome scale analysis of differential mRNA expression of Helicoverpa zea insect cells infected with a H. armigera baculovirus.
Infections
Genomes of parasitic nematodes (Meloidogyne hapla, Meloidogyne incognita, Ascaris suum and Brugia malayi) have a reduced complement of small RNA interference pathway genes: knockdown can reduce host infectivity of M. incognita.
Infections
Genomic Characterization of Intron-containing T7-like Phage phiL7 of Xanthomonas campestris.
Infections
Genomic Diversity and Evolution of Quasispecies in Newcastle Disease Virus Infections.
Infections
Genomic diversity of "Norwalk like viruses" (NLVs): pediatric infections in a Brazilian shantytown.
Infections
Genotype 3-hepatitis C virus' last line of defense.
Infections
Genotypic analysis of Mycobacterium tuberculosis from medieval human remains.
Infections
Genotyping of Cucumber mosaic virus isolates in western New York State during epidemic years: Characterization of an emergent plant virus population.
Infections
Grouper Mx confers resistance to nodavirus and interacts with coat protein.
Infections
Halting HCV Replication with NS5A Inhibitors and NS5B Polymerase Inhibitors: Effective New Treatments of HCV Infection.
Infections
HCV replication in PBMC and its influence on interferon therapy.
Infections
HDAC6 Restricts Influenza A Virus by Deacetylation of the RNA Polymerase PA Subunit.
Infections
Heat shock protein 70 is necessary for Rice stripe virus infection in plants.
Infections
Hepatitis C virus nonstructural protein 5A (NS5A) is an RNA-binding protein.
Infections
Hepatitis C virus NS2/3 protease regulates HCV IRES-dependent translation and NS5B RdRp activity.
Infections
Hepatitis C virus NS3 inhibitors: current and future perspectives.
Infections
Hepatitis C Virus NS5A Protein Promotes the Lysosomal Degradation of Hepatocyte Nuclear Factor 1? via Chaperone-Mediated Autophagy.
Infections
Hepatitis C Virus NS5A Targets Nucleosome Assembly Protein NAP1L1 To Control the Innate Cellular Response.
Infections
Hepatitis C virus replicates in the same immune cell subsets in chronic hepatitis C and occult infection.
Infections
Hepatitis E virus polymerase binds to IFIT1 to protect the viral RNA from IFIT1-mediated translation inhibition.
Infections
Heterogeneous Nuclear Ribonucleoprotein M Facilitates Enterovirus Infection.
Infections
High-Level Expression of Functionally Active Dengue-2 Non-Structural Antigen 1 Production in Escherichia coli.
Infections
Highlights in the development of new antiviral agents.
Infections
Highly pathogenic avian influenza viruses do not inhibit interferon synthesis in infected chickens but can override the interferon-induced antiviral state.
Infections
Highly purified cucumber mosaic virus-induced RNA-dependent RNA polymerase does not contain any of the full length translation products of the genomic RNAs.
Infections
Highly Sensitive Detection of Zika Virus Nonstructural Protein 1 in Serum Samples by a Two-Site Nanobody ELISA.
Infections
HIV seroconversion during pregnancy and risk for mother-to-infant transmission.
Infections
Hsp90 Inhibitors Exhibit Resistance-Free Antiviral Activity against Respiratory Syncytial Virus.
Infections
Human Enterovirus Group B Viruses Rely on Vimentin Dynamics for Efficient Processing of Viral Nonstructural Proteins.
Infections
Human immunodeficiency virus type 1 RNA polymerase chain reaction reasonably excludes infection in exposed infants.
Infections
Human parvovirus B19 infection causes cell cycle arrest of human erythroid progenitors at late S phase that favors viral DNA replication.
Infections
Identification and characterization of a double-stranded RNA- reovirus temperature-sensitive mutant defective in minor core protein mu2.
Infections
Identification and characterization of the alc gene product of bacteriophage T4.
Infections
Identification of a new HIV type 1 circulating BF intersubtype recombinant form (CRF47_BF) in Spain.
Infections
Identification of an export control sequence and a requirement for the KH domains in ICP27 from herpes simplex virus type 1.
Infections
Identification of beta-subunit of bacterial RNA-polymerase--a non-species-specific bacterial protein--as target of antibodies in primary biliary cirrhosis.
Infections
Identification of GII.14[P7] norovirus and its genomic mutations from a case of long-term infection in a post-symptomatic individual.
Infections
Identification of hepatoprotective flavonolignans from silymarin.
Infections
Identification of novel inhibitors of HCV RNA-dependent RNA polymerase by pharmacophore-based virtual screening and in vitro evaluation.
Infections
Identification of Positively Charged Residues in Enterovirus 71 Capsid Protein VP1 Essential for Production of Infectious Particles.
Infections
Identification of potential inhibitors for HCV NS5b of genotype 4a by combining dynamic simulation, protein-ligand interaction fingerprint, 3D pharmacophore, docking and 3D QSAR.
Infections
Identification of protein interactions of grapevine fanleaf virus RNA-dependent RNA polymerase during infection of Nicotiana benthamiana by affinity purification and tandem mass spectrometry.
Infections
Identification of specific antigenic epitope at N-terminal segment of enterovirus 71 (EV-71) VP1 protein and characterization of its use in recombinant form for early diagnosis of EV-71 infection.
Infections
Identification of the cleavage site and determinants required for poliovirus 3CPro-catalyzed cleavage of human TATA-binding transcription factor TBP.
Infections
Identification of two forms of Q{beta} replicase with different thermal stabilities but identical RNA replication activity.
Infections
Identifying the RNA polymerases that synthesize specific transcripts of the Autographa californica nuclear polyhedrosis virus.
Infections
Immunoassay targeting nonstructural protein 5 to differentiate West Nile virus infection from dengue and St. Louis encephalitis virus infections and from flavivirus vaccination.
Infections
Immunofluorescence-based biosensor for the determination of dengue virus NS1 in clinical samples.
Infections
Immunohistochemical and Taqman real-time PCR detection of mycobacterial infections in fish.
Infections
Importance of primer selection for the detection of hepatitis C virus RNA with the polymerase chain reaction assay.
Infections
Improved immunodetection of Taura syndrome virus using a monoclonal antibody specific for heterologously expressed VP1 capsid protein.
Infections
Improved serodiagnosis of hepatitis C virus infection with synthetic peptide antigen from capsid protein.
Infections
Improving dengue viral antigens detection in dengue patient serum specimens using a low pH glycine buffer treatment.
Infections
In Rhizobium leguminosarum, NodD represses its own transcription by competing with RNA polymerase for binding sites.
Infections
In Situ Tagged nsp15 Reveals Interactions with Coronavirus Replication/Transcription Complex-Associated Proteins.
Infections
In vitro inhibition of enterovirus 71 infection with a nickel ion/chitosan microcomposite.
Infections
In vitro product of an RNA polymerase induced in broadbean by infection with broadbean mottle virus.
Infections
In vitro synthesis of late bacteriophage phi 29 RNA.
Infections
In vitro transcription of pe38/polyhedrin hybrid promoters reveals sequences essential for recognition by the baculovirus-induced RNA polymerase and for the strength of very late viral promoters.
Infections
Increased transmission of vertical hepatitis C virus (HCV) infection to human immunodeficiency virus (HIV)-infected infants of HIV- and HCV-coinfected women.
Infections
Induction of RNA polymerase II activity in Junin virus-infected cells.
Infections
Infection with a Brazilian isolate of Zika virus generates RIG-I stimulatory RNA and the viral NS5 protein blocks type I IFN induction and signalling.
Infections
Influenza A(H5N2) virus antibodies in humans after contact with infected poultry, Taiwan, 2012.
Infections
Influenza Virus Exploits an Interferon-Independent lncRNA to Preserve Viral RNA Synthesis through Stabilizing Viral RNA Polymerase PB1.
Infections
Infrequent development of resistance in genotype 1-6 hepatitis C virus-infected subjects treated with sofosbuvir in phase 2 and 3 clinical trials.
Infections
Inhibition of hepatitis C virus RNA replication by 2'-modified nucleoside analogs.
Infections
Inhibition of host cell transcription by poliovirus: cleavage of transcription factor CREB by poliovirus-encoded protease 3Cpro.
Infections
Inhibition of influenza A virus replication by rifampicin and selenocystamine.
Infections
Inhibition of transcription of cytosine-containing DNA in vitro by the alc gene product of bacteriophage T4.
Infections
Inhibitors of the HCV NS5B polymerase: new hope for the treatment of hepatitis C infections.
Infections
Inhibitors of the Hepatitis C Virus Polymerase; Mode of Action and Resistance.
Infections
Initial binding of the broad spectrum antiviral nucleoside ribavirin to the hepatitis C virus RNA polymerase.
Infections
Initial results of efficacy and safety of Sofosbuvir among Pakistani Population: A real life trial - Hepatitis Eradication Accuracy Trial of Sofosbuvir (HEATS).
Infections
Initiation of transcription at phage T4 late promoters with purified RNA polymerase.
Infections
Initiation of transcription by bacteriophage T4-modified RNA polymerase independently of host sigma factor.
Infections
Integration of satellite bacteriophage P4 in Escherichia coli. DNA sequences of the phage and host regions involved in site-specific recombination.
Infections
Interferon-based combination treatment for chronic hepatitis C in the era of direct acting antivirals.
Infections
Interplay between co-divergence and cross-species transmission in the evolutionary history of bat coronaviruses.
Infections
Isolation of an RNA-directed RNA polymerase-specific cDNA clone from tomato.
Infections
Kinetic measurements of Escherichia coli RNA polymerase association with bacteriophage T7 early promoters.
Infections
Kinetic study of alterations in the host RNA polymerase and protein synthesis during phage Xp 10 infection.
Infections
KSHV RNA-binding protein ORF57 inhibits P-body formation to promote viral multiplication by interaction with Ago2 and GW182.
Infections
Kunjin RNA replication and applications of Kunjin replicons.
Infections
Lactoferrin inhibits enterovirus 71 infection by binding to VP1 protein and host cells.
Infections
Lassa Virus but Not Highly Pathogenic New World Arenaviruses Restrict Immunostimulatory dsRNA Accumulation During Infection.
Infections
Leader protein of foot-and-mouth disease virus is required for cleavage of the p220 component of the cap-binding protein complex.
Infections
Learning from our foes: a novel vaccine concept for influenza virus.
Infections
Ledipasvir/sofosbuvir fixed-dose combination for treatment of hepatitis C virus genotype 4 infection.
Infections
Limited overlap between phylogenetic HIV and hepatitis C virus clusters illustrates the dynamic sexual network structure of Dutch HIV-infected MSM.
Infections
Lipid droplet-binding protein TIP47 regulates hepatitis C Virus RNA replication through interaction with the viral NS5A protein.
Infections
Localization of the Escherichia coli RNA polymerase beta' subunit residue phosphorylated by bacteriophage T7 kinase Gp0.7.
Infections
Locus-specific gene expression pattern suggests a unique propagation strategy for a giant algal virus.
Infections
Longitudinal analysis of human immunodeficiency virus type 1-specific cytotoxic T lymphocyte responses: a predominant gag-specific response is associated with nonprogressive infection.
Infections
Loss of sigma-factor of RNA polymerase of Xanthomonas campestris pv. oryzae during phage Xp10 infection.
Infections
Lycorine, a non-nucleoside RNA dependent RNA polymerase inhibitor, as potential treatment for emerging coronavirus infections.
Infections
Lytic Infection with Murine Gammaherpesvirus 68 Activates Host and Viral RNA Polymerase III Promoters and Enhances Noncoding RNA Expression.
Infections
Management of post liver transplantation recurrent hepatitis C infection with directly acting antiviral drugs: a review.
Infections
Manipulated bio antimicrobial peptides from probiotic bacteria as proposed drugs for COVID-19 disease.
Infections
Mapping of Transcription Termination within the S Segment of SFTS Phlebovirus Facilitated Generation of NSs Deletant Viruses.
Infections
Mass spectrometric analysis of host cell proteins interacting with dengue virus nonstructural protein 1 in dengue virus-infected HepG2 cells.
Infections
Maternal and Neonatal Outcomes during Dengue Infection Outbreak at a Tertiary National Hospital in Endemic Area of Indonesia.
Infections
Mechanism of action and antiviral activity of benzimidazole-based allosteric inhibitors of the hepatitis C virus RNA-dependent RNA polymerase.
Infections
Mitotic stability of infection-induced resistance to plum pox potyvirus associated with transgene silencing and DNA methylation.
Infections
Mixed HCV Infection of Genotype 1B and Other Genotypes Influences Non-response during Daclatasvir + Asunaprevir Combination Therapy.
Infections
Model suggesting that replication of influenza virus is regulated by stabilization of replicative intermediates.
Infections
Modification of RNA polymerase after T3 phage infection of Escherichia coli B.
Infections
Modification of RNA polymerase IIO subspecies after poliovirus infection.
Infections
Modulation of vaccine-induced immune responses to hepatitis C virus in rhesus macaques by altering priming before adenovirus boosting.
Infections
Modulatory effects of the human heat shock protein 70 on DNA vaccination.
Infections
Molecular characterization of the small nonstructural proteins of parvovirus Aleutian mink disease virus (AMDV) during infection.
Infections
Molecular cloning and characterization of grouper Kr?ppel-like factor 9 gene: Involvement in the fish immune response to viral infection.
Infections
Molecular cloning of Kuruma shrimp Marsupenaeus japonicus endonuclease-reverse transcriptase and its positive role in white spot syndrome virus and Vibrio alginolyticus infection.
Infections
Molecular detection of murine norovirus from experimentally and spontaneously infected mice.
Infections
Molecular docking and dynamics studies of Nicotinamide Riboside as a potential multi-target nutraceutical against SARS-CoV-2 entry, replication, and transcription: A new insight.
Infections
Molecular dynamics analysis of N-acetyl-D-glucosamine against specific SARS-CoV-2's pathogenicity factors.
Infections
Molecular epidemiology of an enterovirus A71 outbreak associated with severe neurological disease, Spain, 2016.
Infections
Molecular genetic and structural modeling studies of Staphylococcus aureus RNA polymerase and the fitness of rifampin resistance genotypes in relation to clinical prevalence.
Infections
Molecular pathways: rodent parvoviruses--mechanisms of oncolysis and prospects for clinical cancer treatment.
Infections
Mouse norovirus replication is associated with virus-induced vesicle clusters originating from membranes derived from the secretory pathway.
Infections
mRNA expression of proinflammatory cytokines in mouse CNS correlates with replication rate of semliki forest virus but not with the strain of viral proteins.
Infections
Multiple isoelectric forms of poliovirus RNA-dependent RNA polymerase: evidence for phosphorylation.
Infections
Multivalent binding of the partially disordered SARS-CoV-2 nucleocapsid phosphoprotein dimer to RNA.
Infections
Mutations in nonstructural protein 5A gene and response to interferon in hepatitis C virus genotype 2 infection.
Infections
Mutations in the nonstructural protein 5A gene and response to interferon in patients with chronic hepatitis C virus 1b infection.
Infections
Mutations in the nonstructural protein 5A gene and response to interferon therapy in young patients with chronic hepatitis C virus 1b infection.
Infections
Natural infection of free-ranging mandrills (Mandrillus sphinx) by enteroviruses and astroviruses in southern Gabon.
Infections
New antiviral agents for hepatitis C.
Infections
New Non-Nucleocide NS5B Protein Inhibitors for the Treatment of Chronic Hepatitis C Infection.
Infections
No Clinically Relevant Drug-Drug Interactions between Methadone or Buprenorphine-Naloxone and Antiviral Combination Glecaprevir and Pibrentasvir.
Infections
No viral gene is able to elicit RNA-dependent RNA polymerase in cucumber mosaic virus-infected cucumber cotyledons.
Infections
Non-nucleoside inhibitors of the HCV NS5B polymerase: progress in the discovery and development of novel agents for the treatment of HCV infections.
Infections
Nonstructural protein 1-specific immunoglobulin m and g antibody capture enzyme-linked immunosorbent assays in diagnosis of flaviviral infections in humans.
Infections
Nonstructural protein 11 (nsp11) of porcine reproductive and respiratory syndrome virus (PRRSV) promotes PRRSV infection in MARC-145 cells.
Infections
Nonstructural protein NS26 of grass carp reovirus is a principal regulator for viral replication and infection.
Infections
Nonstructural protein Pns12 of rice dwarf virus is a principal regulator for viral replication and infection in its insect vector.
Infections
Norovirus infection results in eIF2? independent host translation shut-off and remodels the G3BP1 interactome evading stress granule formation.
Infections
Novel Flavivirus Antiviral That Targets the Host Nuclear Transport Importin ?/?1 Heterodimer.
Infections
Novel functions of the alphavirus nonstructural protein nsP3 C-terminal region.
Infections
NS1 glycoprotein detection in serum and urine as an electrochemical screening immunosensor for dengue and Zika virus.
Infections
NS5 Conservative Site Is Required for Zika Virus to Restrict the RIG-I Signaling.
Infections
NS5B polymerase inhibitors in phase II clinical trials for HCV infection.
Infections
Nuclear exportin 1 facilitates turnip mosaic virus infection by exporting the sumoylated viral replicase and by repressing plant immunity.
Infections
Nuclear localization of dengue virus (DENV) 1-4 non-structural protein 5; protection against all 4 DENV serotypes by the inhibitor Ivermectin.
Infections
Nucleocytoplasmic shuttling of the West Nile virus RNA-dependent RNA polymerase NS5 is critical to infection.
Infections
Nucleotide sequence and transcription of a bacteriophage 29 early promoter.
Infections
Number and position of mutations in the interferon (IFN) sensitivity-determining region of the gene for nonstructural protein 5A correlate with IFN efficacy in hepatitis C virus genotype 1b infection.
Infections
Ombitasvir/Paritaprevir/Ritonavir Plus Dasabuvir: A Review in Chronic HCV Genotype 1 Infection.
Infections
On the chemical nature of alteration and modification of DNA dependent RNA polymerase of E. coli after T4 infection.
Infections
On the effect of bacteriophage infection on host RNA polymerase.
Infections
Open-label phase 2 study of faldaprevir, deleobuvir and ribavirin in Japanese treatment-naive patients with chronic hepatitis C virus genotype 1 infection.
Infections
Optimizing T-705 (favipiravir) treatment of severe influenza B virus infection in the immunocompromised mouse model.
Infections
Oral immunization of mice using Bifidobacterium longum expressing VP1 protein from enterovirus 71.
Infections
Organization and expression of the poxvirus genome.
Infections
OsRDR6 plays role in host defense against double-stranded RNA virus, Rice Dwarf Phytoreovirus.
Infections
Overexpression of microRNA gga-miR-21 in chicken fibroblasts suppresses replication of infectious bursal disease virus through inhibiting VP1 translation.
Infections
Parameters of RNA-dependent RNA polymerase activity in a mengovirus-infected Ehrlich ascites carcinoma cell-free system.
Infections
Permissive replication of homologous murine rotavirus in the mouse intestine is primarily regulated by VP4 and NSP1.
Infections
Persistence of antibodies to West Nile virus nonstructural protein 5.
Infections
Phage T4 infection restricts rRNA synthesis by E. coli RNA polymerase.
Infections
Pharmacokinetic, Pharmacodynamic, and Drug-Interaction Profile of the Hepatitis C Virus NS5B Polymerase Inhibitor Sofosbuvir.
Infections
Pharmacokinetics of hepatitis C virus NS5A inhibitor JNJ-56914845 (GSK2336805) in subjects with hepatic impairment.
Infections
Phenotypic characterization of temperature-sensitive mutants of vaccinia virus with mutations in a 135,000-Mr subunit of the virion-associated DNA-dependent RNA polymerase.
Infections
Phenyl substituted 3-hydroxypyridin-2(1H)-ones: Inhibitors of influenza A endonuclease.
Infections
Phenyl substituted 4-hydroxypyridazin-3(2H)-ones and 5-hydroxypyrimidin-4(3H)-ones: inhibitors of influenza A endonuclease.
Infections
Phosphorylation of the beta' Subunit of RNA Polymerase and Other Host Proteins upon phiCd1 Infection of Caulobacter crescentus.
Infections
Phosphorylation of the viral nonstructural protein NS1 during MVMp infection of A9 cells.
Infections
Physical and functional domains of the herpes simplex virus transcriptional regulatory protein ICP4.
Infections
Plant-Produced Anti-Enterovirus 71 (EV71) Monoclonal Antibody Efficiently Protects Mice Against EV71 Infection.
Infections
Poliovirus-induced modification of host cell RNA polymerase IIO is prevented by cycloheximide and zinc.
Infections
Porcine deltacoronavirus nucleocapsid protein antagonizes IFN-? production by impairing dsRNA and PACT binding to RIG-I.
Infections
Porcine Reproductive and Respiratory Syndrome Virus Infection Induces both eIF2? Phosphorylation-Dependent and -Independent Host Translation Shutoff.
Infections
Porcine reproductive and respiratory syndrome virus nsp1? and nsp11 antagonize the antiviral activity of cholesterol-25-hydroxylase via lysosomal degradation.
Infections
Porcine transmissible gastroenteritis virus nonstructural protein 2 contributes to inflammation via NF-?B activation.
Infections
Potential Phosphorylation of Viral Nonstructural Protein 1 in Dengue Virus Infection.
Infections
Preclinical and Clinical Resistance Profile of EDP-239, a Novel HCV NS5A Inhibitor.
Infections
Preclinical Characterization of PC786, an Inhaled Small-Molecule Respiratory Syncytial Virus L Protein Polymerase Inhibitor.
Infections
Prevalence and characteristics of naturally occurring sofosbuvir resistance-associated variants in patients with hepatitis C virus genotype 1b infection.
Infections
Prevalence and genetic characterization of human coronaviruses in southern Thailand from July 2009 to January 2011.
Infections
Prevalence and molecular epidemiology of human coronavirus HKU1 in patients with acute respiratory illness.
Infections
Prevalence of antibodies to human parvovirus B19 nonstructural protein in persons with various clinical outcomes following B19 infection.
Infections
Prevalence of GB virus type C/hepatitis G virus RNA and of anti-E2 in individuals at high or low risk for blood-borne or sexually transmitted viruses: evidence of sexual and parenteral transmission.
Infections
Proceedings: Modification of E. coli RNA polymerase induced by T4 phage infection.
Infections
Production and characterisation of a viral RNA-dependent RNA polymerase induced in Escherichia coli Q. 13 by infection with bacteriophage Q .
Infections
Production and characterization of monospecific and bispecific antibodies against dengue virus NS1 protein.
Infections
Program of bacteriophage gh-1 DNA transcription in infected Pseudomonas putida.
Infections
Progress and development of small molecule HCV antivirals.
Infections
Protection against lethal enterovirus 71 infection in newborn mice by passive immunization with subunit VP1 vaccines and inactivated virus.
Infections
Protective immune response in mice vaccinated with a recombinant adenovirus containing capsid precursor polypeptide P1, nonstructural protein 2A and 3C protease genes (P12A3C) of encephalomyocarditis virus.
Infections
Purification and identification of the RNA-dependent RNA polymerase of foot-and-mouth disease virus.
Infections
Purification and properties of RNA polymerase of phage KB1.
Infections
Q63, a novel DENV2 RdRp non-nucleoside inhibitor, inhibited DENV2 replication and infection.
Infections
Randomized, placebo-controlled, single-ascending-dose study of BMS-791325, a hepatitis C virus (HCV) NS5B polymerase inhibitor, in HCV genotype 1 infection.
Infections
Re-evaluation of the pathogenic roles of nonstructural protein 1 and its antibodies during dengue virus infection.
Infections
Rearrangements of rotavirus genomic segment 11 are generated during acute infection of immunocompetent children and do not occur at random.
Infections
Recent advances in drug discovery of benzothiadiazine and related analogs as HCV NS5B polymerase inhibitors.
Infections
Recent advances in the development of NS5B polymerase inhibitors for the treatment of hepatitis C virus infection.
Infections
Recognition of the measles virus nucleocapsid as a mechanism of IRF-3 activation.
Infections
Recombinant fusion protein and DNA vaccines against foot and mouth disease virus infection in guinea pig and swine.
Infections
Recombinant Rotaviruses Rescued by Reverse Genetics Reveal the Role of NSP5 Hyperphosphorylation in the Assembly of Viral Factories.
Infections
Recombinant VP1 protein as a potential marker for the diagnosis of acute hepatitis A virus infection.
Infections
Recovery of NV knockout infectious hematopoietic necrosis virus expressing foreign genes.
Infections
Reduced Featured k-NN Classifier Model Optimal for Classification of Dengue Fever from Salivary Raman Spectra.
Infections
Reduction of the risk of transfusion-transmitted human immunodeficiency virus (HIV) infection by using an HIV antigen/antibody combination assay in blood donation screening in Cameroon.
Infections
Regulation of Chlamydia Gene Expression by Tandem Promoters with Different Temporal Patterns.
Infections
Regulation of promoter selection by the bacteriophage T7 RNA polymerase in vitro.
Infections
Regulation of single-strand RNA synthesis of alfalfa mosaic virus in non-transgenic cowpea protoplasts by the viral coat protein.
Infections
Regulation of the temporal synthesis of proteins in bacteriophage BF23-infected cells.
Infections
Regulation of transcription of the Xp10 genome in bacteriophage-infected Xanthomonas campestris pv. oryzae.
Infections
Relationship between nonstructural protein 1 detection and plasma virus load in Dengue patients.
Infections
Relationship between RNA polymerase II and efficiency of vaccinia virus replication.
Infections
Release of RNA polymerase from vero cell mitochondria after herpes simplex virus type 1 infection.
Infections
Repeated exposure to 5D9, an inhibitor of 3D polymerase, effectively limits the replication of foot-and-mouth disease virus in host cells.
Infections
Replication-competent influenza A virus that encodes a split-green fluorescent protein-tagged PB2 polymerase subunit allows live-cell imaging of the virus life cycle.
Infections
Resistance analysis and characterization of NITD008 as an adenosine analog inhibitor against hepatitis C virus.
Infections
Respiratory Syncytial Virus NS1 Protein Colocalizes with Mitochondrial Antiviral Signaling Protein MAVS following Infection.
Infections
Restriction enzyme accessibility and RNA polymerase localization on transcriptionally active SV40 minichromosomes isolated late in infection.
Infections
Rhinovirus 16 2A Protease Affects Nuclear Localization of 3CD during Infection.
Infections
Ribavirin for Hepatitis E Virus Infection After Organ Transplantation: A Large European Retrospective Multicenter Study.
Infections
Ribavirin resistance in hepatitis C virus replicon-containing cell lines conferred by changes in the cell line or mutations in the replicon RNA.
Infections
Rifampicin-resistant bacteriophage PBS2 infection and RNA polymerase in Bacillus subtilis.
Infections
Rifampin-resistance-associated mutations in the rifampin-resistance-determining region of the rpoB gene of Mycobacterium tuberculosis clinical isolates in Shanghai, PR China.
Infections
RNA elements required for RNA recombination function as replication enhancers in vitro and in vivo in a plus-strand RNA virus.
Infections
RNA ligands activate the Machupo virus polymerase and guide promoter usage.
Infections
RNA polymerase activity and protein synthesis in brome mosaic virus-infected protoplasts.
Infections
RNA polymerase activity following infection with murine leukemia virus.
Infections
RNA polymerase and the shut-off of host RNA and protein synthesis in T4 phage infection.
Infections
RNA polymerase from phage SP01-infected and uninfected Bacillus subtilis.
Infections
RNA polymerase-associated transcription specificity factor encoded by vaccinia virus.
Infections
RNA recombination in Hepatitis delta virus: Identification of a novel naturally occurring recombinant.
Infections
RNA-binding properties of a translational activator, the adenovirus L4 100-kilodalton protein.
Infections
RNA-binding protein CPEB1 remodels host and viral RNA landscapes.
Infections
RNA-dependent RNA polymerase (RdRp) inhibitors: The current landscape and repurposing for the COVID-19 pandemic.
Infections
RNA-dependent RNA polymerase 1 delays the accumulation of viroids in infected plants.
Infections
RNA-dependent RNA polymerase 6 of rice (Oryza sativa) plays role in host defense against negative-strand RNA virus, Rice stripe virus.
Infections
RNA-dependent RNA polymerase, RdRP, a promising therapeutic target for cancer and potentially COVID-19.
Infections
RNA-Free and Ribonucleoprotein-Associated Influenza Virus Polymerases Directly Bind the Serine-5-Phosphorylated Carboxyl-Terminal Domain of Host RNA Polymerase II.
Infections
RNAi-based inhibition of infectious myonecrosis virus replication in Pacific white shrimp Litopenaeus vannamei.
Infections
Role for the paramyxovirus genomic promoter in limiting host cell antiviral responses and cell killing.
Infections
Role of Enteroviral RNA-Dependent RNA Polymerase in Regulation of MDA5-Mediated Beta Interferon Activation.
Infections
Role of intrafamilial transmission in high prevalence of hepatitis C virus in Egypt.
Infections
Role of Noncoding RNAs in the Regulation of P-TEFb Availability and Enzymatic Activity.
Infections
Roles of polyamines in the replication of animal viruses.
Infections
Roles of viroplasm-like structures formed by nonstructural protein NSs in infection with severe fever with thrombocytopenia syndrome virus.
Infections
Rotavirus nonstructural protein NSP4 induces heterotypic antibody responses during natural infection in children.
Infections
Safety and Efficacy of Elbasvir/Grazoprevir in Patients With Hepatitis C Virus Infection and Compensated Cirrhosis: An Integrated Analysis.
Infections
Safety, tolerability, and pharmacokinetics of AL-335 in healthy volunteers and hepatitis C virus-infected subjects.
Infections
Salicylic acid-mediated and RNA-silencing defense mechanisms cooperate in the restriction of systemic spread of plum pox virus in tobacco.
Infections
SARS-CoV-2 NSP12 Protein Is Not an Interferon-? Antagonist.
Infections
Schlafen 11 Restricts Flavivirus Replication.
Infections
Screening for Antiviral Medaka Haploid Embryonic Stem Cells by Genome Wide Mutagenesis.
Infections
Sequence analysis of group B rotavirus gene 1 and definition of a rotavirus-specific sequence motif within the RNA polymerase gene.
Infections
Seraprevir and sofosbuvir for treatment of chronic hepatitis C virus infection: A single-arm, open-label, phase 3 trial.
Infections
Serial real-time RT-PCR and serology measurements substantially improve Zika and Dengue virus infection classification in a co-circulation area.
Infections
Seroepidemiology of human bocavirus in Hokkaido prefecture, Japan.
Infections
Serologic Prevalence of MPV1 in Mouse Strains in a Commercial Laboratory Mouse Colony Determined by Using VP1 Antigen.
Infections
Serotype-Specific Anti-Dengue Virus NS1 Mouse Antibodies Cross-React with prM and Are Potentially Involved in Virus Production.
Infections
Serum concentration and increased temperature alter Mayaro virus RNA and protein synthesis in Aedes albopictus (mosquito)-infected cells.
Infections
Serum hepatitis C virus RNA levels in chronic hepatitis C--importance for outcome of interferon alfa-2b treatment.
Infections
Significance of NS5B Substitutions in Genotype 1b Hepatitis C Virus Evaluated by Bioinformatics Analysis.
Infections
Silencing the tobacco gene for RNA-dependent RNA polymerase 1 and infection by potato virus Y cause remodeling of cellular organelles.
Infections
Simultaneous detection of both hepatitis B virus DNA and hepatitis C virus RNA using a combined one-step polymerase chain reaction technique.
Infections
Sindbis virus RNA polymerase is degraded by the N-end rule pathway.
Infections
Single amino acid substitutions in the coat protein and RNA-dependent RNA polymerase alleviated the virulence of Cucumber green mottle mosaic virus and conferred cross protection against severe infection.
Infections
Site of synthesis of membrane and nonmembrane proteins of vesicular stomatitis virus.
Infections
SIVMAC Vpx improves the transduction of dendritic cells with nonintegrative HIV-1-derived vectors.
Infections
Sofosbuvir in the treatment of chronic hepatitis C: new dog, new tricks.
Infections
Sofosbuvir plus ribavirin in Japanese patients with chronic genotype 2 HCV infection: an open-label, phase 3 trial.
Infections
Sofosbuvir/velpatasvir fixed-dose combination for the treatment of chronic hepatitis C virus infection.
Infections
Sofosbuvir/Velpatasvir: A Review in Chronic Hepatitis C.
Infections
Stable polypeptides associated with the 250S mengovirus-induced RNA polymerase structure.
Infections
Stereoselective Synthesis and Biological Evaluations of Novel 3'-Deoxy-4'-azaribonucleosides as Inhibitors of Hepatitis C Virus RNA Replication.
Infections
Structural comparison of the Autographa californica nuclear polyhedrosis virus-induced RNA polymerase and the three nuclear RNA polymerases from the host, Spodoptera frugiperda.
Infections
Structure and replication of hepatitis delta virus RNA.
Infections
Structure of the enterovirus D68 RNA-dependent RNA polymerase in complex with NADPH implicates an inhibitor binding site in the RNA template tunnel.
Infections
Structure of the Qbeta replicase, an RNA-dependent RNA polymerase consisting of viral and host proteins.
Infections
Structure of the SARS-CoV-2 RNA-dependent RNA polymerase in the presence of favipiravir-RTP.
Infections
Structure-based virtual screening, synthesis and SAR of novel inhibitors of hepatitis C virus NS5B polymerase.
Infections
Subcellular proteomic analysis of human host cells infected with H3N2 swine influenza virus.
Infections
Substantial portions of the 5' and intercistronic noncoding regions of cowpea chlorotic mottle virus RNA3 are dispensable for systemic infection but influence viral competitiveness and infection pathology.
Infections
Substrate selectivity of Dengue and Zika virus NS5 polymerase towards 2'-modified nucleotide analogues.
Infections
SUMO Modification Stabilizes Enterovirus 71 Polymerase 3D to Facilitate Viral Replication.
Infections
SUMO1 Modification Facilitates Avibirnavirus Replication by Stabilizing Polymerase VP1.
Infections
Suppression of murine cytomegalovirus (MCMV) replication with a DNA vaccine encoding MCMV M84 (a homolog of human cytomegalovirus pp65).
Infections
Synthesis and Biological Characterization of Aryl Uracil Inhibitors of Hepatitis C Virus NS5B Polymerase: Discovery of ABT-072, a trans-Stilbene Analog with Good Oral Bioavailability.
Infections
Synthesis, posttranslational modifications, and nuclear transport of polyomavirus major capsid protein VP1.
Infections
Systemic antiviral silencing in plants.
Infections
Systemic Expression of a Viral RdRP Protects Against Retrovirus Infection and Disease.
Infections
T Cell Responses to Nonstructural Protein 3 Distinguish Infections by Dengue and Zika Viruses.
Infections
T7 phage protein Gp2 inhibits the Escherichia coli RNA polymerase by antagonizing stable DNA strand separation near the transcription start site.
Infections
TDP-43 proteinopathy in Theiler's murine encephalomyelitis virus infection.
Infections
Temperature-sensitive mutants of vesicular stomatitis virus: viral RNA synthesis in cells infected with mutants belonging to complementation group I.
Infections
Template requirements for recognition and copying by Sindbis virus RNA-dependent RNA polymerase.
Infections
Template-dependent RNA polymerase from black beetle virus-infected Drosophila melanogaster cells.
Infections
Temporal studies of factors associated with changes in transcription during Q fever.
Infections
Termination of transcription of the coliphage T7 "early" operon in vitro: slowness of enzyme release, and lack of any role for sigma.
Infections
The 2b protein and C-terminal region of the 2a protein indispensably facilitate systemic movement of cucumber mosaic virus in radish with supplementary function by either the 3a or the coat protein.
Infections
The 2b protein of cucumoviruses has a role in promoting the cell-to-cell movement of pseudorecombinant viruses.
Infections
The ?CPG1 chlamydiaphage can infect Chlamydia trachomatis and significantly reduce its infectivity.
Infections
The ABL-MYC retrovirus generates antigen-specific plasmacytomas by in vitro infection of activated B lymphocytes from spleen and other murine lymphoid organs.
Infections
The active form of the norovirus RNA-dependent RNA polymerase is a homodimer with cooperative activity.
Infections
The Arabidopsis AtNPR1 inversely modulates defense responses against fungal, bacterial, or viral pathogens while conferring hypersensitivity to abiotic stresses in transgenic rice.
Infections
The barley stripe mosaic virus 58-kilodalton beta(b) protein is a multifunctional RNA binding protein.
Infections
The CaMV transactivator/viroplasmin interferes with RDR6-dependent trans-acting and secondary siRNA pathways in Arabidopsis.
Infections
The changing face of Hepatitis C: Recent Advances on HCV Inhibitors Targeting NS5A.
Infections
The Dengue Virus Nonstructural Protein 1 (NS1) Is Secreted from Mosquito Cells in Association with the Intracellular Cholesterol Transporter Chaperone Caveolin Complex.
Infections
The effect of a bacteriophage T4-induced polypeptide on host RNA polymerase interaction with promoters.
Infections
The effects of herpes simplex virus type 1 on cellular DNA-dependent RNA polymerase activities.
Infections
The Escherichia coli RNA polymerase.anti-sigma 70 AsiA complex utilizes alpha-carboxyl-terminal domain upstream promoter contacts to transcribe from a -10/-35 promoter.
Infections
The expression of IFN-? is suppressed by the viral 3D polymerase via its impact on PGAM5 expression during enterovirus D68 infection.
Infections
The Good, the Bad, and the Shocking: The Multiple Roles of Dengue Virus Nonstructural Protein 1 in Protection and Pathogenesis.
Infections
The hepatitis C revolution part 2: difficult-to-treat groups and experimental approaches.
Infections
The humoral response to heat shock protein 70 in human and murine Schistosomiasis mansoni.
Infections
The influence of RNA-dependent RNA polymerase 1 on potato virus Y infection and on other antiviral response genes.
Infections
The late expression factors 8 and 9 and possibly the phosphoprotein p78/83 of Autographa californica multicapsid nucleopolyhedrovirus are components of the virus-induced RNA polymerase.
Infections
The Mechanism and Clinical Outcome of patients with Corona Virus Disease 2019 Whose Nucleic Acid Test has changed from negative to positive, and the therapeutic efficacy of Favipiravir: A structured summary of a study protocol for a randomised controlled trial.
Infections
The NS5 protein of the virulent West Nile virus NY99 strain is a potent antagonist of type I interferon-mediated JAK-STAT signaling.
Infections
The Nucleocapsid Protein and Nonstructural Protein 10 of Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus Enhance CD83 Production via NF-?B and Sp1 Signaling Pathways.
Infections
The oncogenic role of NS5A of hepatitis C virus is mediated by up-regulation of survivin gene expression in the Hepatocellular cell through p53 and NF-?B pathways.
Infections
The optimal temperature for RNA replication in cells infected by Soil-borne wheat mosaic virus is 17 degrees C.
Infections
The ORF, regulated synthesis, and persistence-specific variation of influenza C viral NS1 protein.
Infections
The overexpression of the trypanosomatid-exclusive TcRBP19 RNA-binding protein affects cellular infection by Trypanosoma cruzi.
Infections
The pathogenesis of infection with minute virus of mice depends on expression of the small nonstructural protein NS2 and on the genotype of the allotropic determinants VP1 and VP2.
Infections
The phage T4 MotA transcription factor contains a novel DNA binding motif that specifically recognizes modified DNA.
Infections
The Phage-Encoded N-Acetyltransferase Rac Mediates Inactivation of Pseudomonas aeruginosa Transcription by Cleavage of the RNA Polymerase Alpha Subunit.
Infections
The plant defense response to cucumber mosaic virus in cowpea is elicited by the viral polymerase gene and affects virus accumulation in single cells.
Infections
The presence of resistance mutations to protease and polymerase inhibitors in Hepatitis C virus sequences from the Los Alamos databank.
Infections
The regulation of transcription in bacteriophage T5-infected Escherichia coli.
Infections
The RNA polymerase of influenza a virus is stabilized by interaction with its viral RNA promoter.
Infections
The RNA-dependent RNA polymerase of cowpea is not involved in cowpea mosaic virus RNA replication: immunological evidence.
Infections
The strategy of infection as a criterion for phylogenetic relationships of non-coli phages morphologically similar to phage T7.
Infections
The switch between acute and persistent paramyxovirus infection caused by single amino acid substitutions in the RNA polymerase P subunit.
Infections
The tail sheath of bacteriophage N4 interacts with the Escherichia coli receptor.
Infections
The tyrosine 73 and serine 83 dephosphorylation of H1N1 swine influenza virus NS1 protein attenuates virus replication and induces high levels of beta interferon.
Infections
The use of dengue nonstructural protein 1 antigen for the early diagnosis during the febrile stage in patients with dengue infection.
Infections
The variations of VP1 protein might be associated with nervous system symptoms caused by enterovirus 71 infection.
Infections
The viral mechanism of Reye's syndrome.
Infections
The VP1 protein of avian encephalomyelitis virus is a major host-protective immunogen that serves as diagnostic potential.
Infections
Therapeutic targeting of measles virus polymerase with ERDRP-0519 suppresses all RNA synthesis activity.
Infections
Thiolutin resistant mutants of Escherichia coli are they RNA chain initiation mutants?
Infections
Three-dimensional model for the isolated recombinant influenza virus polymerase heterotrimer.
Infections
Time to viral suppression is not related to achievement of SVR12 in HCV GT1-infected patients treated with ombitasvir/paritaprevir/ritonavir and dasabuvir with or without ribavirin.
Infections
Transcription from a bacteriophage T4 middle promoter using T4 motA protein and phage-modified RNA polymerase.
Infections
Transcription of adenoviral genetic information in isolated nuclei. Characterization of viral RNA sequences synthesized in vitro.
Infections
Transcription of bacteriophage T4 genome in vitro. Heterogeneity of RNA polymerase in crude extracts of normal and T4-infected Escherichia coli B.
Infections
Transcription of the bovine parvovirus genome in isolated nuclei.
Infections
Transcription Profiling of Bacillus subtilis Cells Infected with AR9, a Giant Phage Encoding Two Multisubunit RNA Polymerases.
Infections
Transcription-independent DNA translocation of bacteriophage T7 DNA into Escherichia coli.
Infections
Transcriptional regulation of three double-stranded RNA segments of bacteriophage phi 6 in vitro.
Infections
Transcriptional takeover by sigma appropriation: remodelling of the sigma70 subunit of Escherichia coli RNA polymerase by the bacteriophage T4 activator MotA and co-activator AsiA.
Infections
Transcriptional termination at the end of the early region of bacteriophages T3 and T7 is not affected by polarity suppressors.
Infections
Transcriptionally defective nucleocapsids of vesicular stomatitis virus from cells treated with indomethacin.
Infections
Transcriptome analysis of yellow passion fruit in response to cucumber mosaic virus infection.
Infections
Transducin ?-like 1 X-linked receptor 1 (TBLR1) affects RGNNV infection through negative regulation of interferon immune response in orange-spotted grouper, Epinephelus coioides.
Infections
Transient activation of RNA polymerase in Escherichia coli B after infection with bacteriophage T4.
Infections
Translation and processing of mouse hepatitis virus virion RNA in a cell-free system.
Infections
Transmission genetics of drug-resistant hepatitis C virus.
Infections
Treatment of hepatitis C virus in HIV patients: a review.
Infections
Tumefactive multiple sclerosis and hepatitis C virus 2a/2C infection: Dual benefit of long-term interferon beta-1a therapy?
Infections
Type I interferon antagonistic properties of influenza B virus polymerase proteins.
Infections
Ultrastructural visualization of hepatitis C virus components in human and primate liver biopsies.
Infections
Update on hepatitis C virus resistance to direct-acting antiviral agents.
Infections
Upregulation of CHOP participates in caspase activation and virus release in human astrovirus-infected cells.
Infections
Use and interpretation of HCV diagnostic tests in the clinical setting.
Infections
Use of dengue nonstructural protein 1 antigen for the early diagnosis of dengue infection.
Infections
Utility of a rapid immunochromatographic strip test in detecting canine parvovirus infection compared with polymerase chain reaction.
Infections
VAPC, an Human Endogenous Inhibitor for Hepatitis C Virus (HCV) Infection, Is Intrinsically Unstructured but Forms a "Fuzzy Complex" with HCV NS5B.
Infections
Variable Inhibition of Zika Virus Replication by Different Wolbachia Strains in Mosquito Cell Cultures.
Infections
Variations in the Viral NS5B Region in Japanese Patients with Chronic Hepatitis C Virus Genotype 1b Infection. No Specific Amino Acid Substitution Was Identified as Determinants of Treatment Response to Interferon/Ribavirin Combination Therapy.
Infections
Variations of hepatitis C virus NS5B sequence (nucleotides 8261-8566) do not correlate with response to interferon-alpha therapy.
Infections
Victorivirus, a new genus of fungal viruses in the family Totiviridae.
Infections
Viral replication. Structural basis for RNA replication by the hepatitis C virus polymerase.
Infections
Viral RNA synthesis and levels of DNA-dependent RNA polymerases during replication of adenovirus 2.
Infections
Viral RNA-dependent RNA polymerase mutants display an altered mutation spectrum resulting in attenuation in both mosquito and vertebrate hosts.
Infections
Viral, host and environmental factors that favor anthropozoonotic spillover of coronaviruses: An opinionated review, focusing on SARS-CoV, MERS-CoV and SARS-CoV-2.
Infections
Virion-associated RNA polymerase required for bacteriophage N4 development.
Infections
Virological, serological, and clinical features of an outbreak of acute gastroenteritis due to recombinant genogroup II norovirus in an infant home.
Infections
Viruses within the Flaviviridae decrease CD4 expression and inhibit HIV replication in human CD4+ cells.
Infections
Visualizing the beta interferon response in mice during infection with influenza A viruses expressing or lacking nonstructural protein 1.
Infections
Vitamin D and lumisterol novel metabolites can inhibit SARS-CoV-2 replication machinery enzymes.
Infections
X-ray crystal structure of the polymerase domain of the bacteriophage N4 virion RNA polymerase.
Infections
[Cloning and infectivity analysis of the cDNAs of tobacco mosaic virus (tomato strain) and its attenuated virus(N14) genomes]
Infections
[Coupling of bacteriophage T7 DNA penetration with its transcription, during infection]
Infections
[Detection of human parvovirus B19 nonstructural protein DNA by nested- polymerase chain reaction in pregnant women]
Infections
[Drug clinics. How I treat HIV infections. II. Nucleoside reverse transcriptase inhibitors]
Infections
[Expression of recombinant VP1 protein of enterovirus 71 and development of serological assay for detection of EV71 infection]
Infections
[Marburg and Ebola hemorrhagic fevers--pathogens, epidemiology and therapy].
Infections
[Persistent Shallot virus X infection correlates with transcriptional repression of plant cell RNA-dependent RNA polymerase and DCL proteins in plant roots].
Infections
[Pharma-clinics. How I treat ... HIV infection. III. Non-nucleoside reverse transcriptase inhibitors]
Infections
[Structure, function and regulation of expression of influenza virus matrix M1 protein]
Infections
[Study on specificity of IgM antibody response in patients with coxsackie virus B infection]
Infections
[Transcription and replication of influenza virus genome]
Infertility
C. elegans SUP-46, an HNRNPM family RNA-binding protein that prevents paternally-mediated epigenetic sterility.
Infertility
Characterization of the mouse Dazap1 gene encoding an RNA-binding protein that interacts with infertility factors DAZ and DAZL.
Infertility
Comparative testis proteome of cattleyak from different developmental stages.
Infertility
Emaravirus-specific degenerate PCR primers allowed the identification of partial RNA-dependent RNA polymerase sequences of Maize red stripe virus and Pigeonpea sterility mosaic virus.
Infertility
KEX2 mutations suppress RNA polymerase II mutants and alter the temperature range of yeast cell growth.
Infertility
Requirement for ERI/DICER Complex in Endogenous RNAi and Sperm Development in Caenorhabditis elegans.
Infertility
The RNA-binding specificity of the mouse Dazl protein.
Infertility, Female
Chromatin Modification and Global Transcriptional Silencing in the Oocyte Mediated by the mRNA Decay Activator ZFP36L2.
Infertility, Female
The Drosophila RNA-binding protein Lark is required for the organization of the actin cytoskeleton and Hu-li tai shao localization during oogenesis.
Infertility, Male
Ablation of the Sam68 gene impairs female fertility and gonadotropin-dependent follicle development.
Infertility, Male
Cold-inducible RNA-binding protein (CIRP) regulates target mRNA stabilization in the mouse testis.
Infertility, Male
Molecular cloning of human and mouse DJ-1 genes and identification of Sp1-dependent activation of the human DJ-1 promoter.
Infertility, Male
Motor coordination defects in mice deficient for the Sam68 RNA-binding protein.
Infertility, Male
[Long non-coding RNAs in plants].
Influenza in Birds
A Single Amino Acid in the M1 Protein Responsible for the Different Pathogenic Potentials of H5N1 Highly Pathogenic Avian Influenza Virus Strains.
Influenza in Birds
Annexin A2 (ANXA2) interacts with nonstructural protein 1 and promotes the replication of highly pathogenic H5N1 avian influenza virus.
Influenza in Birds
Avian Influenza A Virus Polymerase Recruits Cellular RNA Helicase eIF4A3 to Promote Viral mRNA Splicing and Spliced mRNA Nuclear Export.
Influenza in Birds
Biochemical impact of the host adaptation associated PB2 E627K mutation on the temperature-dependent RNA synthesis kinetics of influenza A virus polymerase complex.
Influenza in Birds
China makes an impressive breakthrough in avian influenza virus research - Discovering the "heart" of avian infl uenza virus.
Influenza in Birds
Cloning and expression of highly pathogenic avian influenza virus full-length nonstructural gene in Pichia pastoris.
Influenza in Birds
Comparative study of virion transcriptase of some influenza virus strains.
Influenza in Birds
Computational identification of reassortments in avian influenza viruses.
Influenza in Birds
Correlation between polymerase activity and pathogenicity in two duck H5N1 influenza viruses suggests that the polymerase contributes to pathogenicity.
Influenza in Birds
Detection of antibodies to the nonstructural protein (NS1) of avian influenza viruses allows distinction between vaccinated and infected chickens.
Influenza in Birds
Effect of adamantane derivatives on the activity of orthomyxovirus RNA-dependent RNA polymerase.
Influenza in Birds
Expanding the frontiers of existing antiviral drugs: possible effects of HIV-1 protease inhibitors against SARS and avian influenza.
Influenza in Birds
Expression profiles of interferon-related genes in cells infected with influenza A viruses or transiently transfected with plasmids encoding viral RNA polymerase.
Influenza in Birds
Host ANP32A mediates the assembly of the influenza virus replicase.
Influenza in Birds
Host restriction of influenza virus polymerase activity by PB2 627E is diminished on short viral templates in a nucleoprotein-independent manner.
Influenza in Birds
Human HA and polymerase subunit PB2 proteins confer transmission of an avian influenza virus through the air.
Influenza in Birds
In vitro inhibition of negative strand virus transcriptase activity by proteins soluble in acidic chloroform-methanol.
Influenza in Birds
Interaction of avian influenza virus NS1 protein and nucleolar and coiled-body phosphoprotein 1.
Influenza in Birds
Interaction of M protein and RNP of fowl plague virus in vitro.
Influenza in Birds
Interaction of Polymerase Subunit PB2 and NP with Importin alpha1 Is a Determinant of Host Range of Influenza A Virus.
Influenza in Birds
Novel mutations in avian PA in combination with an adaptive mutation in PR8 NP exacerbate the virulence of PR8-derived recombinant influenza A viruses in mice.
Influenza in Birds
Novel reassortant highly pathogenic H5N2 avian influenza viruses in poultry in China.
Influenza in Birds
NP and NS1 proteins of H5N1 virus significantly upregulated IFITM1, IFITM2, and IFITM3 in A549 cells.
Influenza in Birds
Pathogenicity and transmissibility of an H9N2 avian influenza virus that naturally harbors the mammalian-adaptive molecular factors in the hemagglutinin and PB2 proteins.
Influenza in Birds
Poly-ADP Ribosyl Polymerase 1 (PARP1) Regulates Influenza A Virus Polymerase.
Influenza in Birds
Reassortments among Avian Influenza A(H5N1) Viruses Circulating in Indonesia, 2015-2016.
Influenza in Birds
Screen Anti-influenza Lead Compounds That Target the PA(C) Subunit of H5N1 Viral RNA Polymerase.
Influenza in Birds
Screening for lead compounds and herbal extracts with potential anti-influenza viral activity.
Influenza in Birds
Structure and Function of the Influenza Virus Transcription and Replication Machinery.
Influenza in Birds
The PB2 subunit of the influenza virus RNA polymerase affects virulence by interacting with the mitochondrial antiviral signaling protein and inhibiting expression of beta interferon.
Influenza in Birds
Virion transcriptase activity of rimantadine-sensitive and rimantadine-resistant variants of human influenza virus.
Influenza in Birds
Virulence of H5N1 avian influenza virus enhanced by a 15-nucleotide deletion in the viral nonstructural gene.
Influenza in Birds
[Preparation and characterization the polyclonal antibody of the nonstructural protein of human highly pathogenic H5N1 avian influenza viruses].
Influenza, Human
(19)F NMR reveals multiple conformations at the dimer interface of the nonstructural protein 1 effector domain from influenza a virus.
Influenza, Human
1918 HA and the viral RNA polymerase complex enhance viral pathogenicity, but only HA induces aberrant host responses in mice.
Influenza, Human
A 48-amino-acid region of influenza A virus PB1 protein is sufficient for complex formation with PA.
Influenza, Human
A Broad Anti-influenza Hybrid Small Molecule That Potently Disrupts the Interaction of Polymerase Acidic Protein-Basic Protein 1 (PA-PB1) Subunits.
Influenza, Human
A cluster of conserved basic amino acids near the C-terminus of the PB1 subunit of the influenza virus RNA polymerase is involved in the regulation of viral transcription.
Influenza, Human
A Dual-Functioning 5'-PPP-NS1shRNA that Activates a RIG-I Antiviral Pathway and Suppresses Influenza NS1.
Influenza, Human
A frame shift mutation in a hot spot region of the nuclear autoantigen La (SS-B).
Influenza, Human
A Mechanism for Priming and Realignment during Influenza A Virus Replication.
Influenza, Human
A Mechanism for the Activation of the Influenza Virus Transcriptase.
Influenza, Human
A multi-functional enzyme with RNA polymerase and RNase activities: molecular anatomy of influenza virus RNA polymerase.
Influenza, Human
A Naturally Occurring Deletion in the Effector Domain of H5N1 Swine Influenza Virus Nonstructural Protein 1 Regulates Viral Fitness and Host Innate Immunity.
Influenza, Human
A new method for reconstituting influenza polymerase and RNA in vitro: a study of the promoter elements for cRNA and vRNA synthesis in vitro and viral rescue in vivo.
Influenza, Human
A new promoter-binding site in the PB1 subunit of the influenza A virus polymerase.
Influenza, Human
A non-PCR SPR platform using RNase H to detect MicroRNA 29a-3p from throat swabs of human subjects with influenza A virus H1N1 infection.
Influenza, Human
A novel antiviral agent which inhibits the endonuclease of influenza viruses.
Influenza, Human
A novel aqueous extract from rice fermented with Aspergillus oryzae and Saccharomyces cerevisiae possesses an anti-influenza A virus activity.
Influenza, Human
A novel function of the N-terminal domain of PA in assembly of influenza A virus RNA polymerase.
Influenza, Human
A novel functional site in the PB2 subunit of influenza A virus essential for acetyl-CoA interaction, RNA polymerase activity, and viral replication.
Influenza, Human
A novel mechanism of enhanced transcription activity and fidelity for influenza A viral RNA-dependent RNA polymerase.
Influenza, Human
A novel protein characterization based on Pseudo Amino Acids composition and Star-like graph topological indices.
Influenza, Human
A Novel Role for PDZ-Binding Motif of Influenza A Virus Nonstructural Protein 1 in Regulation of Host Susceptibility to Postinfluenza Bacterial Superinfections.
Influenza, Human
A novel small-molecule inhibitor of influenza A virus acts by suppressing PA endonuclease activity of the viral polymerase.
Influenza, Human
A novel SUMOylation site in the influenza a virus NS1 protein identified with a highly sensitive FRET assay.
Influenza, Human
A novel type of influenza vaccine: safety and immunogenicity of replication-deficient influenza virus created by deletion of the interferon antagonist NS1.
Influenza, Human
A Nucleolar Protein, Ribosomal RNA Processing 1 Homolog B (RRP1B), Enhances the Recruitment of Cellular mRNA in Influenza Virus Transcription.
Influenza, Human
A Parallel Phenotypic Versus Target-Based Screening Strategy for RNA-Dependent RNA Polymerase Inhibitors of the Influenza A Virus.
Influenza, Human
A peptide derived from the C-terminus of PB1 inhibits influenza virus replication by interfering with viral polymerase assembly.
Influenza, Human
A prospective, randomized, open-label trial of early versus late favipiravir in hospitalized patients with COVID-19.
Influenza, Human
A quantitative strategy to detect changes in accessibility of protein regions to chemical modification on heterodimerization.
Influenza, Human
A rapid and highly sensitive method for diagnosis of equine influenza by antigen detection using immuno-PCR.
Influenza, Human
A recombinant influenza virus vaccine expressing the F protein of respiratory syncytial virus.
Influenza, Human
A sensitive, single-tube assay to measure the enzymatic activities of influenza RNA polymerase and other poly(A) polymerases: application to kinetic and inhibitor analysis.
Influenza, Human
A Single Amino Acid in the Polymerase Acidic Protein Determines the Pathogenicity of Influenza B Viruses.
Influenza, Human
A single amino acid mutation in the PA subunit of the influenza virus RNA polymerase inhibits endonucleolytic cleavage of capped RNAs.
Influenza, Human
A single amino acid mutation in the PA subunit of the influenza virus RNA polymerase promotes the generation of defective interfering RNAs.
Influenza, Human
A single point mutation (Y89F) within the non-structural protein 1 of influenza A viruses limits epithelial cell tropism and virulence in mice.
Influenza, Human
A single-nucleotide natural variation (U4 to C4) in an influenza A virus promoter exhibits a large structural change: implications for differential viral RNA synthesis by RNA-dependent RNA polymerase.
Influenza, Human
Acetylation of the influenza A virus polymerase subunit PA in the N-terminal domain positively regulates its endonuclease activity.
Influenza, Human
Activation of influenza virus RNA polymerase by the 5' and 3' terminal duplex of genomic RNA.
Influenza, Human
Activation of influenza virus-associated RNA polymerase by cap-1 structure (m7GpppNm).
Influenza, Human
Activation of monocytes by three OspA vaccine candidates: lipoprotein OspA is a potent stimulator of monokines.
Influenza, Human
Activation of phosphatidylinositol 3-kinase signaling by the nonstructural NS1 protein is not conserved among type A and B influenza viruses.
Influenza, Human
Amino acid residues in the N-terminal region of the PA subunit of influenza A virus RNA polymerase play a critical role in protein stability, endonuclease activity, cap binding, and virion RNA promoter binding.
Influenza, Human
Amino acid substitutions affecting aspartic acid 605 and valine 606 decrease the interaction strength between the influenza virus RNA polymerase PB2 '627' domain and the viral nucleoprotein.
Influenza, Human
An A14U Substitution in the 3' Noncoding Region of the M Segment of Viral RNA Supports Replication of Influenza Virus with an NS1 Deletion by Modulating Alternative Splicing of M Segment mRNAs.
Influenza, Human
An in vivo study of the replication origin in the influenza virus complementary RNA.
Influenza, Human
An inhibitor of the particle-associated RNA-dependent RNA polymerase of influenza A and B viruses.
Influenza, Human
Analysis of oropouche virus L protein amino acid sequence showed the presence of an additional conserved region that could harbour an important role for the polymerase activity.
Influenza, Human
Analysis of the in vitro product of an RNA-dependent RNA polymerase isolated from influenza virus-infected cells.
Influenza, Human
Annotating Protein Functional Residues by Coupling High-Throughput Fitness Profile and Homologous-Structure Analysis.
Influenza, Human
Anthralin Suppresses the Proliferation of Influenza Virus by Inhibiting the Cap-Binding and Endonuclease Activity of Viral RNA Polymerase.
Influenza, Human
Anti-influenza activity of c60 fullerene derivatives.
Influenza, Human
Anti-influenza activity of marchantins, macrocyclic bisbibenzyls contained in liverworts.
Influenza, Human
Anti-influenza activity of phenethylphenylphthalimide analogs derived from thalidomide.
Influenza, Human
Antibody-scanning and epitope-tagging methods; molecular mapping of proteins using antibodies.
Influenza, Human
Antigenic reactivity and electrophoretic migrational heterogeneity of the three polymerase proteins of type A human and animal influenza viruses.
Influenza, Human
Antigenic variation in the influenza A virus nonstructural protein, NS1.
Influenza, Human
Antisense oligonucleotides directed against the viral RNA polymerase gene enhance survival of mice infected with influenza A.
Influenza, Human
Antiviral activity of double-stranded RNA-binding protein PACT against influenza A virus mediated via suppression of viral RNA polymerase.
Influenza, Human
Antiviral activity of SA-2 against influenza A virus in vitro/vivo and its inhibition of RNA polymerase.
Influenza, Human
Antiviral effects of single-stranded polynucleotide inhibitors of the influenza virion-associated transcriptase against influenza virus infection of hamsters and ferrets.
Influenza, Human
Antiviral protective immunity induced by major histocompatibility complex class I molecule-restricted viral T-lymphocyte epitopes inserted in various positions in immunologically self and nonself proteins.
Influenza, Human
Antiviral response in pandemic influenza viruses.
Influenza, Human
Antiviral susceptibility of influenza viruses isolated from patients pre- and post-administration of favipiravir.
Influenza, Human
Apical transport of influenza A virus ribonucleoprotein requires Rab11-positive recycling endosome.
Influenza, Human
Application of a split luciferase complementation assay for the detection of viral protein-protein interactions.
Influenza, Human
Application of three duplex real-time PCR assays for simultaneous detection of human seasonal and avian influenza viruses.
Influenza, Human
Approved Antiviral Drugs over the Past 50 Years.
Influenza, Human
Artificial hybrids of influenza A virus RNA polymerase reveal PA subunit modulates its thermal sensitivity.
Influenza, Human
Assays to Measure the Activity of Influenza Virus Polymerase.
Influenza, Human
Association of the influenza A virus RNA-dependent RNA polymerase with cellular RNA polymerase II.
Influenza, Human
Association of the influenza virus RNA polymerase subunit PB2 with the host chaperonin CCT.
Influenza, Human
Avian Chaperonin Containing TCP1 Subunit 5 Supports Influenza A Virus Replication by Interacting With Viral Nucleoprotein, PB1, and PB2 Proteins.
Influenza, Human
AZT acts as an anti-influenza nucleotide triphosphate targeting the catalytic site of A/PR/8/34/H1N1 RNA dependent RNA polymerase.
Influenza, Human
Baloxavir Marboxil for Prophylaxis against Influenza in Household Contacts.
Influenza, Human
Baloxavir treatment delays influenza B virus transmission in ferrets and results in limited generation of drug-resistant variants.
Influenza, Human
Base-pair formation between noncapped influenza virus in vitro transcripts and 18S rRNA in rabbit reticulocyte 80S ribosome-mRNA complexes detected by psoralen photoreaction.
Influenza, Human
Base-pairing promotes leader selection to prime in vitro influenza genome transcription.
Influenza, Human
Basic amino acids in the N-terminal half of the PB2 subunit of influenza virus RNA polymerase are involved in both transcription and replication.
Influenza, Human
Binding mode prediction and inhibitor design of anti-influenza virus diketo acids targeting metalloenzyme RNA polymerase by molecular docking.
Influenza, Human
Biochemical and kinetic analysis of the influenza virus RNA polymerase purified from insect cells.
Influenza, Human
Biochemical characterization of enzyme fidelity of influenza A virus RNA polymerase complex.
Influenza, Human
Biochemical characterization of recombinant influenza A polymerase heterotrimer complex: Endonuclease activity and evaluation of inhibitors.
Influenza, Human
Biochemical characterization of recombinant influenza A polymerase heterotrimer complex: Polymerase activity and mechanisms of action of nucleotide analogs.
Influenza, Human
Biochemical studies on capped RNA primers identify a class of oligonucleotide inhibitors of the influenza virus RNA polymerase.
Influenza, Human
Biogenesis, assembly, and export of viral messenger ribonucleoproteins in the influenza A virus infected cell.
Influenza, Human
Biophysical characterization of sites of host adaptive mutation in the influenza A virus RNA polymerase PB2 RNA-binding domain.
Influenza, Human
Biophysical characterization of the complex between double-stranded RNA and the N-terminal domain of the NS1 protein from influenza A virus: evidence for a novel RNA-binding mode.
Influenza, Human
Broad influenza-specific CD8+ T-cell responses in humanized mice vaccinated with influenza virus vaccines.
Influenza, Human
Bunyaviridae RNA polymerases (L-protein) have an N-terminal, influenza-like endonuclease domain, essential for viral cap-dependent transcription.
Influenza, Human
Capped mRNAs may stimulate the influenza virion polymerase by allosteric modulation.
Influenza, Human
Cellular cap-binding proteins associate with influenza virus mRNAs.
Influenza, Human
Cellular DDX21 RNA Helicase Inhibits Influenza A Virus Replication but Is Counteracted by the Viral NS1 Protein.
Influenza, Human
Cellular human CLE/C14orf166 protein interacts with influenza virus polymerase and is required for viral replication.
Influenza, Human
Cellular protein HAX1 interacts with the influenza A virus PA polymerase subunit and impedes its nuclear translocation.
Influenza, Human
Characterization of a mitochondrial-targeting signal in the PB2 protein of influenza viruses.
Influenza, Human
Characterization of a temperature-sensitive mutant in the RNA polymerase PB2 subunit gene of influenza A/WSN/33 virus.
Influenza, Human
Characterization of PA-N terminal domain of Influenza A polymerase reveals sequence specific RNA cleavage.
Influenza, Human
Characterization of susceptibility variants of poliovirus grown in the presence of favipiravir.
Influenza, Human
Characterization of the interaction between the influenza A virus polymerase subunit PB1 and the host nuclear import factor Ran-binding protein 5.
Influenza, Human
Characterization of the RNA-fork model of virion RNA in the initiation of transcription in influenza A virus.
Influenza, Human
Cis-acting signals and trans-acting factors involved in influenza virus RNA synthesis.
Influenza, Human
Cloning DNA sequences from influenza viral RNA segments.
Influenza, Human
Co-incorporation of the PB2 and PA polymerase subunits from human H3N2 influenza virus is a critical determinant of the replication of reassortant ribonucleoprotein complexes.
Influenza, Human
Codon Deletions in the Influenza A Virus PA Gene Generate Temperature-Sensitive Viruses.
Influenza, Human
Codon usage characteristics of PB2 gene in influenza A H7N9 virus from different host species.
Influenza, Human
Combinations of favipiravir and peramivir for the treatment of pandemic influenza A/California/04/2009 (H1N1) virus infections in mice.
Influenza, Human
Comparative studies of wild-type and cold-mutant (temperature-sensitive) influenza viruses: independent segregation of temperature-sensitivity of virus replication from temperature-sensitivity of virion transcriptase activity during recombination of mutant A/Ann Arbor/6/60 with wild-type H3N2 strains.
Influenza, Human
Comparative study of virion transcriptase of some influenza virus strains.
Influenza, Human
Comparison of Influenza Virus Particle Purification Using Magnetic Sulfated Cellulose Particles with an Established Centrifugation Method for Analytics.
Influenza, Human
Comparison of the three large polymerase proteins of influenza A, B, and C viruses.
Influenza, Human
Comparison of two reconstituted systems for in vitro transcription and replication of influenza virus.
Influenza, Human
Comparison of vRNA and cRNA based reporters for detection of influenza replication.
Influenza, Human
Complex formation between influenza virus polymerase proteins expressed in Xenopus oocytes.
Influenza, Human
Comprehensive assessment of amino acid substitutions in the trimeric RNA polymerase complex of influenza A virus detected in clinical trials of baloxavir marboxil.
Influenza, Human
Comprehensive proteomic analysis of influenza virus polymerase complex reveals a novel association with mitochondrial proteins and RNA polymerase accessory factors.
Influenza, Human
Computational analysis of the effect of polymerase acidic (PA) gene mutation F35L in the 2009 pandemic influenza A (H1N1) virus on binding aspects of mononucleotides in the endonuclease domain.
Influenza, Human
Computational Studies of Selected Transition Metal Complexes as Potential Drug Candidates against the SARS-CoV-2 Virus.
Influenza, Human
Contribution of double-stranded RNA and CPSF30 binding domains of influenza virus NS1 to the inhibition of type I interferon production and activation of human dendritic cells.
Influenza, Human
Correlation between polymerase activity and pathogenicity in two duck H5N1 influenza viruses suggests that the polymerase contributes to pathogenicity.
Influenza, Human
Cryo-EM Structure of Influenza Virus RNA Polymerase Complex at 4.3 Å Resolution.
Influenza, Human
Cryptoporic acid E from Cryptoporus volvatus inhibits influenza virus replication in vitro.
Influenza, Human
Crystal structure of an avian influenza polymerase PA(N) reveals an endonuclease active site.
Influenza, Human
Crystal structure of the polymerase PA(C)-PB1(N) complex from an avian influenza H5N1 virus.
Influenza, Human
Crystal structure of the RNA-dependent RNA polymerase from influenza C virus.
Influenza, Human
Crystal structure of the unique RNA-binding domain of the influenza virus NS1 protein.
Influenza, Human
Crystallization and preliminary X-ray diffraction studies of a surface mutant of the middle domain of PB2 from human influenza A (H1N1) virus.
Influenza, Human
Crystallization and X-ray diffraction analysis of the RNA primer/promoter-binding domain of influenza A virus RNA-dependent RNA polymerase PB2.
Influenza, Human
Crystallographic Fragment Screening and Structure-Based Optimization Yields a New Class of Influenza Endonuclease Inhibitors.
Influenza, Human
Current and novel antiviral strategies for influenza infection.
Influenza, Human
Cyclin T1/CDK9 interacts with influenza A viral polymerase and facilitates its association with cellular RNA Polymerase II.
Influenza, Human
Deep sequencing reveals the eight facets of the influenza A/HongKong/1/1968 (H3N2) virus cap-snatching process.
Influenza, Human
Defective assembly of influenza A virus due to a mutation in the polymerase subunit PA.
Influenza, Human
Definition of the minimal viral components required for the initiation of unprimed RNA synthesis by influenza virus RNA polymerase.
Influenza, Human
Design and Construction of Aroyl-Hydrazone Derivatives: Synthesis, Crystal Structure, Molecular Docking and Their Biological Activities.
Influenza, Human
Detailed Molecular Interactions of Favipiravir with SARS-CoV-2, SARS-CoV, MERS-CoV, and Influenza Virus Polymerases In Silico.
Influenza, Human
Detection of antibodies to the nonstructural protein (NS1) of influenza A virus allows distinction between vaccinated and infected horses.
Influenza, Human
Detection of variants with reduced baloxavir marboxil susceptibility after treatment of children with influenza A during the 2018/2019 influenza season.
Influenza, Human
Development of a method for evaluating the mRNA transcription activity of influenza virus RNA-dependent RNA polymerase through real-time reverse transcription polymerase chain reaction.
Influenza, Human
Development of an HTS assay for the search of anti-influenza agents targeting the interaction of viral RNA with the NS1 protein.
Influenza, Human
Development of cycling probe based real-time PCR methodology for influenza A viruses possessing the PA/I38T amino acid substitution associated with reduced baloxavir susceptibility.
Influenza, Human
Diagnostic approach for differentiating infected from vaccinated poultry on the basis of antibodies to NS1, the nonstructural protein of influenza A virus.
Influenza, Human
Different de novo initiation strategies are used by influenza virus RNA polymerase on its cRNA and viral RNA promoters during viral RNA replication.
Influenza, Human
Differential effect of modified capped RNA substrates on influenza virus transcription.
Influenza, Human
Differential effects of NS1 proteins of human pandemic H1N1/2009, avian highly pathogenic H5N1, and low pathogenic H5N2 influenza A viruses on cellular pre-mRNA polyadenylation and mRNA translation.
Influenza, Human
Differential Modulation of Innate Immune Responses in Human Primary Cells by Influenza A Viruses Carrying Human or Avian Nonstructural Protein 1.
Influenza, Human
Differential role of the influenza A virus polymerase PA subunit for vRNA and cRNA promoter binding.
Influenza, Human
Differential roles of viral RNA and cRNA in functional modulation of the influenza virus RNA polymerase.
Influenza, Human
Differentiation of infected and vaccinated animals (DIVA) using the NS1 protein of avian influenza virus.
Influenza, Human
Dihydromyricetin is a new inhibitor of influenza polymerase PB2 subunit and influenza-induced inflammation.
Influenza, Human
Directly reconstructing principal components of heterogeneous particles from cryo-EM images.
Influenza, Human
Discovery of 5-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrazin-2(1H)-one derivatives as new potent PB2 inhibitors.
Influenza, Human
Discovery of anti-influenza nucleoside triphosphates targeting the catalytic site of A/PR/8/34/H1N1 polymerase.
Influenza, Human
Distinct regions of influenza virus PB1 polymerase subunit recognize vRNA and cRNA templates.
Influenza, Human
Distribution of lignin-carbohydrate complex in plant kingdom and its functionality as alternative medicine.
Influenza, Human
DnaJA1/Hsp40 is co-opted by influenza A virus to enhance its viral RNA polymerase activity.
Influenza, Human
Dual R108K and G189D Mutations in the NS1 Protein of A/H1N1 Influenza Virus Counteract Host Innate Immune Responses.
Influenza, Human
Effect of adamantane derivatives on the activity of orthomyxovirus RNA-dependent RNA polymerase.
Influenza, Human
Effect of high salt treatment on influenza B viral protein synthesis in MDCK cells.
Influenza, Human
Effect of ribavirin triphosphate on primer generation and elongation during influenza virus transcription in vitro.
Influenza, Human
Effects of polynucleotide inhibitors on transcriptional events of influenza virions.
Influenza, Human
Effects of selenazofurin and ribavirin and their 5'-triphosphates on replicative functions of influenza A and B viruses.
Influenza, Human
Effects on synaptic activity in cultured hippocampal neurons by influenza A viral proteins.
Influenza, Human
Efficient and regioselective one-step synthesis of 7-aryl-5-methyl- and 5-aryl-7-methyl-2-amino-[1,2,4]triazolo[1,5-a]pyrimidine derivatives.
Influenza, Human
Efficient generation of influenza virus with a mouse RNA polymerase I-driven all-in-one plasmid.
Influenza, Human
Elucidation of basic mechanistic and kinetic properties of influenza endonuclease using chemically synthesized RNAs.
Influenza, Human
Encephalomyocarditis virus disrupts stress granules, the critical platform for triggering antiviral innate immune responses.
Influenza, Human
Enhanced expression of secretable influenza virus neuraminidase in suspension mammalian cells by influenza virus nonstructural protein 1.
Influenza, Human
Enhancement of Virus Replication in An Influenza A Virus NS1-Expresssing 293 Cell Line.
Influenza, Human
Enisamium is a small molecule inhibitor of the influenza A virus and SARS-CoV-2 RNA polymerases.
Influenza, Human
Enisamium Reduces Influenza Virus Shedding and Improves Patient Recovery by Inhibiting Viral RNA Polymerase Activity.
Influenza, Human
Entropy Hotspots for the Binding of Intrinsically Disordered Ligands to a Receptor Domain.
Influenza, Human
Epidemiology of influenza C virus in man: multiple evolutionary lineages and low rate of change.
Influenza, Human
Epitope mapping of the influenza A virus RNA polymerase PA using monoclonal antibodies
Influenza, Human
Epitope mapping of the influenza A virus RNA polymerase PA using monoclonal antibodies.
Influenza, Human
Equine-Like H3 Avian Influenza Viruses in Wild Birds, Chile.
Influenza, Human
Establishment of a Replicon Reporter of the Emerging Tick-Borne Bourbon Virus and Use It for Evaluation of Antivirals.
Influenza, Human
Establishment of canine RNA polymerase I-driven reverse genetics for influenza A virus: its application for H5N1 vaccine production.
Influenza, Human
Establishment of Vero cell RNA polymerase I-driven reverse genetics for influenza A virus and its application for pandemic (H1N1) 2009 influenza virus vaccine production.
Influenza, Human
Estimating the distribution of selection coefficients from phylogenetic data using sitewise mutation-selection models.
Influenza, Human
Ethanolic Extract of Melia Fructus Has Anti-influenza A Virus Activity by Affecting Viral Entry and Viral RNA Polymerase.
Influenza, Human
Eukaryotic translation initiation factor 4GI is a cellular target for NS1 protein, a translational activator of influenza virus.
Influenza, Human
Evidence for the involvement of influenza A (fowl plague Rostock) virus protein P2 in ApG and mRNA primed in vitro RNA synthesis.
Influenza, Human
Evidence that the C-terminal PB2-binding region of the influenza A virus PB1 protein is a discrete alpha-helical domain.
Influenza, Human
Evolution of influenza polymerase: nucleotide sequence of the PB2 gene of A/Chile/1/83 (H1 N1).
Influenza, Human
Evolutionary relatedness of the predicted gene product of RNA segment 2 of the tick-borne Dhori virus and the PB1 polymerase gene of influenza viruses.
Influenza, Human
Expanding the frontiers of existing antiviral drugs: possible effects of HIV-1 protease inhibitors against SARS and avian influenza.
Influenza, Human
Exploring the cycloheptathiophene-3-carboxamide scaffold to disrupt the interactions of the influenza polymerase subunits and obtain potent anti-influenza activity.
Influenza, Human
Exploring the molecular basis of dsRNA recognition by NS1 protein of influenza A virus using molecular dynamics simulation and free energy calculation.
Influenza, Human
Exploring the molecular mechanism of action between drug and RNA polymerase based on partially-resolved spatial structures.
Influenza, Human
Exploring Ugi-Azide Four-Component Reaction Products for Broad-Spectrum Influenza Antivirals with a High Genetic Barrier to Drug Resistance.
Influenza, Human
Expression of functional influenza virus RNA polymerase in the methylotrophic yeast Pichia pastoris.
Influenza, Human
Expression of H3N2 nucleoprotein in maize seeds and immunogenicity in mice.
Influenza, Human
Expression of influenza virus NS2 nonstructural protein in bacteria and localization of NS2 in infected eucaryotic cells.
Influenza, Human
Expression of the nonstructural protein NS1 of equine influenza A virus: detection of anti-NS1 antibody in post infection equine sera.
Influenza, Human
Expression of the three influenza virus polymerase proteins in a single cell allows growth complementation of viral mutants.
Influenza, Human
Expression profiles of interferon-related genes in cells infected with influenza A viruses or transiently transfected with plasmids encoding viral RNA polymerase.
Influenza, Human
Expression, purification, and characterization of orthomyxovirus: influenza transcriptase.
Influenza, Human
Favipiravir (T-705) inhibits Junín virus infection and reduces mortality in a guinea pig model of Argentine hemorrhagic fever.
Influenza, Human
Favipiravir (T-705), a novel viral RNA polymerase inhibitor.
Influenza, Human
Favipiravir: Pharmacokinetics and Concerns About Clinical Trials for 2019-nCoV Infection.
Influenza, Human
Fight against H1N1 Influenza A Virus: Recent Insights towards the Development of Druggable Compounds.
Influenza, Human
Fine mapping of the subunit binding sites of influenza virus RNA polymerase.
Influenza, Human
Flupyranochromene, a novel inhibitor of influenza virus cap-dependent endonuclease, from Penicillium sp. f28743.
Influenza, Human
Free Energy Calculations and Binding Analysis of two Potential Anti-Influenza Drugs with Polymerase Basic Protein-2 (PB2).
Influenza, Human
Functional analysis of conserved motifs in influenza virus PB1 protein.
Influenza, Human
Functional analysis of influenza RNA polymerase activity by the use of caps, oligonucleotides and polynucleotides.
Influenza, Human
Functional association between viral and cellular transcription during influenza virus infection.
Influenza, Human
Functional domains of the influenza A virus PB2 protein: identification of NP- and PB1-binding sites.
Influenza, Human
Functional Genomics Reveals Linkers Critical for Influenza Virus Polymerase.
Influenza, Human
G45R mutation in the nonstructural protein 1 of A/Puerto Rico/8/1934 (H1N1) enhances viral replication independent of dsRNA-binding activity and type I interferon biology.
Influenza, Human
G45R on nonstructural protein 1 of influenza A virus contributes to virulence by increasing the expression of proinflammatory cytokines in mice.
Influenza, Human
Generation and characterization of influenza A viruses with altered polymerase fidelity.
Influenza, Human
Generation and comprehensive analysis of an influenza virus polymerase cellular interaction network.
Influenza, Human
Generation of DelNS1 Influenza Viruses: a Strategy for Optimizing Live Attenuated Influenza Vaccines.
Influenza, Human
Generation of recombinant influenza virus bearing strep tagged PB2 and effective identification of interactional host factors.
Influenza, Human
Genetic analysis of the compatibility between polymerase proteins from human and avian strains of influenza A viruses.
Influenza, Human
Genetic diversity among pandemic 2009 influenza viruses isolated from a transmission chain.
Influenza, Human
Genetic variation and co-evolutionary relationship of RNA polymerase complex segments in influenza A viruses.
Influenza, Human
Genome-wide mutagenesis of influenza virus reveals unique plasticity of the hemagglutinin and NS1 proteins.
Influenza, Human
Global Reprogramming of Host SUMOylation during Influenza Virus Infection.
Influenza, Human
Green tea catechins inhibit the endonuclease activity of influenza A virus RNA polymerase.
Influenza, Human
Growth complementation of influenza virus temperature-sensitive mutants in mouse cells which express the RNA polymerase and nucleoprotein genes.
Influenza, Human
H9N2 Avian Influenza Virus Protein PB1 Enhances the Immune Responses of Bone Marrow-Derived Dendritic Cells by Down-Regulating miR375.
Influenza, Human
Hairpin loop structure in the 3' arm of the influenza A virus virion RNA promoter is required for endonuclease activity.
Influenza, Human
HDAC6 Restricts Influenza A Virus by Deacetylation of the RNA Polymerase PA Subunit.
Influenza, Human
High-resolution structure of the Influenza A virus PB2cap binding domain illuminates the changes induced by ligand binding.
Influenza, Human
High-throughput identification of compounds targeting influenza RNA-dependent RNA polymerase activity.
Influenza, Human
Highlights in the development of new antiviral agents.
Influenza, Human
Highly pathogenic avian influenza viruses do not inhibit interferon synthesis in infected chickens but can override the interferon-induced antiviral state.
Influenza, Human
Homology modeling and examination of the effect of the D92E mutation on the H5N1 nonstructural protein NS1 effector domain.
Influenza, Human
Host ANP32A mediates the assembly of the influenza virus replicase.
Influenza, Human
Host Determinants of Influenza RNA Synthesis.
Influenza, Human
Host factor Ebp1: selective inhibitor of influenza virus transcriptase.
Influenza, Human
Host Interaction Analysis of PA-N155 and PA-N182 in Chicken Cells Reveals an Essential Role of UBA52 for Replication of H5N1 Avian Influenza Virus.
Influenza, Human
Host Protein Moloney Leukemia Virus 10 (MOV10) Acts as a Restriction Factor of Influenza A Virus by Inhibiting the Nuclear Import of the Viral Nucleoprotein.
Influenza, Human
Hsp90 inhibitors reduce influenza virus replication in cell culture.
Influenza, Human
Human and mouse Mx proteins inhibit different steps of the influenza virus multiplication cycle.
Influenza, Human
Human HA and polymerase subunit PB2 proteins confer transmission of an avian influenza virus through the air.
Influenza, Human
Human monoclonal single chain antibodies (HuScFv) that bind to the polymerase proteins of influenza A virus.
Influenza, Human
Human RNA polymerase I-driven reverse genetics for influenza a virus in canine cells.
Influenza, Human
Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor.
Influenza, Human
Identification of a novel compound with antiviral activity against influenza A virus depending on PA subunit of viral RNA polymerase.
Influenza, Human
Identification of host factors that regulate the influenza virus RNA polymerase activity.
Influenza, Human
Identification of Hsp90 as a stimulatory host factor involved in influenza virus RNA synthesis.
Influenza, Human
Identification of human-to-human transmissibility factors in PB2 proteins of influenza A by large-scale mutual information analysis.
Influenza, Human
Identification of the influenza virus transcriptase by affinity-labeling with pyridoxal 5'-phosphate.
Influenza, Human
Identification of the peptide binding motif for HLA-B44, one of the most common HLA-B alleles in the Caucasian population.
Influenza, Human
Identification of the RNA polymerase-binding site on genome RNA of influenza virus.
Influenza, Human
Identification of two nucleotide-binding domains on the PB1 subunit of influenza virus RNA polymerase.
Influenza, Human
Identification of two separate domains in the influenza virus PB1 protein involved in the interaction with the PB2 and PA subunits: a model for the viral RNA polymerase structure.
Influenza, Human
Identification, design and synthesis of novel pyrazolopyridine influenza virus nonstructural protein 1 antagonists.
Influenza, Human
IgG-neutralized influenza virus undergoes primary, but not secondary uncoating in vivo.
Influenza, Human
Immunization with live attenuated influenza viruses that express altered NS1 proteins results in potent and protective memory CD8+ T-cell responses.
Influenza, Human
Immunization with the N-terminal region of the nonstructural protein NS1 promotes survival after challenge with lethal influenza A virus dose.
Influenza, Human
Immunogenicity of an influenza virus-vectored vaccine carrying the hepatitis C virus protein epitopes in mice.
Influenza, Human
Immunologic studies on the influenza A virus nonstructural protein NS1.
Influenza, Human
In vitro assembly of PB2 with a PB1-PA dimer supports a new model of assembly of influenza A virus polymerase subunits into a functional trimeric complex.
Influenza, Human
In vivo analysis of the promoter structure of the influenza virus RNA genome using a transfection system with an engineered RNA.
Influenza, Human
In vivo inhibition of influenza A virus replication by RNA interference targeting the PB2 subunit via intratracheal delivery.
Influenza, Human
Inactivation of influenza and vesicular stomatitis virion RNA polymerase activities by photoreaction with 4'-substituted psoralens.
Influenza, Human
Individual influenza A virus mRNAs show differential dependence on cellular NXF1/TAP for their nuclear export.
Influenza, Human
Influence of membrane (M) protein on influenza A virus virion transcriptase activity in vitro and its susceptibility to rimantadine.
Influenza, Human
Influenza A and B virus intertypic reassortment through compatible viral packaging signals.
Influenza, Human
Influenza A polymerase subunit PB2 possesses overlapping binding sites for polymerase subunit PB1 and human MAVS proteins.
Influenza, Human
Influenza A virus attenuation by codon deoptimization of the NS gene for vaccine development.
Influenza, Human
Influenza A virus cap-snatches host RNAs based on their abundance early after infection.
Influenza, Human
Influenza A virus in vitro transcription: roles of NS1 and NP proteins in regulating RNA synthesis.
Influenza, Human
Influenza A virus lacking the NS1 gene replicates in interferon-deficient systems.
Influenza, Human
Influenza A virus M2 protein triggers mitochondrial DNA-mediated antiviral immune responses.
Influenza, Human
Influenza A virus NS1 protein activates the PI3K/Akt pathway to mediate antiapoptotic signaling responses.
Influenza, Human
Influenza A Virus NS1 Protein Promotes Efficient Nuclear Export of Unspliced Viral M1 mRNA.
Influenza, Human
Influenza A virus NS1 protein-induced JNK activation and apoptosis are not functionally linked.
Influenza, Human
Influenza A virus NS1 targets the ubiquitin ligase TRIM25 to evade recognition by the host viral RNA sensor RIG-I.
Influenza, Human
Influenza A virus polymerase: an attractive target for next-generation anti-influenza therapeutics.
Influenza, Human
Influenza A virus polymerase: structural insights into replication and host adaptation mechanisms.
Influenza, Human
Influenza A virus progeny vRNP trafficking in live infected cells studied with the virus-encoded fluorescently tagged PB2 protein.
Influenza, Human
Influenza A virus RNA polymerase has the ability to stutter at the polyadenylation site of a viral RNA template during RNA replication.
Influenza, Human
Influenza A virus RNA polymerase subunit PB2 is the endonuclease which cleaves host cell mRNA and functions only as the trimeric enzyme.
Influenza, Human
Influenza A virus RNA-dependent RNA polymerase cleaves influenza mRNA in vitro.
Influenza, Human
Influenza A virus RNA-dependent RNA polymerase: analysis of RNA synthesis in vitro.
Influenza, Human
Influenza A virus TRIMs the type I interferon response.
Influenza, Human
Influenza A virus upregulates PRPF8 gene expression to increase virus production.
Influenza, Human
Influenza A virus-generated small RNAs regulate the switch from transcription to replication.
Influenza, Human
Influenza B virus PB1 protein; nucleotide sequence of the genome RNA segment predicts a high degree of structural homology with the corresponding influenza A virus polymerase protein.
Influenza, Human
Influenza C virus RNA 7 codes for a nonstructural protein.
Influenza, Human
Influenza chemotherapy: a review of the present state of art and of new drugs in development.
Influenza, Human
Influenza of age on chromatin transcription in murine tissues using a heterologous and an homologous RNA polymerase.
Influenza, Human
Influenza polymerase encoding mRNAs utilize atypical mRNA nuclear export.
Influenza, Human
Influenza Polymerase Inhibitors: Mechanisms of Action and Resistance.
Influenza, Human
Influenza RNA transcriptase inhibitors: studies in vitro and in vivo.
Influenza, Human
Influenza RNA-Dependent RNA Polymerase (RdRp) Inhibitors: Potential New Therapy for Influenza Treatment.
Influenza, Human
Influenza virion RNA-dependent RNA polymerase: stimulation by guanosine and related compounds.
Influenza, Human
Influenza virion transcriptase: synthesis in vitro of large, polyadenylic acid-containing complementary RNA.
Influenza, Human
Influenza virion-derived viral ribonucleoproteins synthesize both mRNA and cRNA in vitro.
Influenza, Human
Influenza Virus Adaptation PB2-627K Modulates Nucleocapsid Inhibition by the Pathogen Sensor RIG-I.
Influenza, Human
Influenza virus endoribonuclease.
Influenza, Human
Influenza Virus Exploits an Interferon-Independent lncRNA to Preserve Viral RNA Synthesis through Stabilizing Viral RNA Polymerase PB1.
Influenza, Human
Influenza virus genome C4 promoter/origin attenuates its transcription and replication activity by the low polymerase recognition activity.
Influenza, Human
Influenza virus hemagglutinin-specific cytotoxic T cell response induced by polypeptide produced in Escherichia coli.
Influenza, Human
Influenza virus infection induces cellular Ebp1 gene expression.
Influenza, Human
Influenza Virus Infection Induces Host Pyruvate Kinase M Which Interacts with Viral RNA-Dependent RNA Polymerase.
Influenza, Human
Influenza virus inhibits RNA polymerase II elongation.
Influenza, Human
Influenza virus NS1 protein stimulates translation of the M1 protein.
Influenza, Human
Influenza virus PB1 protein is the minimal and essential subunit of RNA polymerase.
Influenza, Human
Influenza virus polymerase inhibitors in clinical development.
Influenza, Human
Influenza virus polymerase subunits co-evolve to ensure proper levels of dimerization of the heterotrimer.
Influenza, Human
Influenza virus RNA polymerase may be activated inside the virion.
Influenza, Human
Influenza virus RNA polymerase PA subunit is a novel serine protease with Ser624 at the active site.
Influenza, Human
Influenza virus RNA polymerase: insights into the mechanisms of viral RNA synthesis.
Influenza, Human
Influenza Virus RNA-Dependent RNA Polymerase and the Host Transcriptional Apparatus.
Influenza, Human
Influenza virus subtype-specific cytotoxic T lymphocytes lyse target cells coated with a protein produced in E. coli.
Influenza, Human
Influenza viruses and cell membranes.
Influenza, Human
Inhibition of influenza A virus matrix and nonstructural gene expression using RNA interference.
Influenza, Human
Inhibition of influenza A virus replication by rifampicin and selenocystamine.
Influenza, Human
Inhibition of influenza A virus replication by RNA interference targeted against the PB1 subunit of the RNA polymerase gene.
Influenza, Human
Inhibition of influenza A virus reproduction by a ribozyme targeted against PB1 mRNA.
Influenza, Human
Inhibition of influenza RNA polymerase by specific antiserum.
Influenza, Human
Inhibition of influenza virus RNA polymerase and nucleoprotein genes expression by unmodified, phosphorothioated, and liposomally encapsulated oligonucleotides.
Influenza, Human
Inhibition of influenza virus RNA polymerase and nucleoprotein of gene expression by antisense oligonucleotides.
Influenza, Human
Inhibition of influenza virus RNA polymerase by 5'-capped short RNA fragments.
Influenza, Human
Inhibition of influenza virus transcription by 2'-deoxy-2'-fluoroguanosine.
Influenza, Human
Inhibition of PA endonuclease activity of influenza virus RNA polymerase by Kampo medicines.
Influenza, Human
Inhibition of retinoic acid-inducible gene I-mediated induction of beta interferon by the NS1 protein of influenza A virus.
Influenza, Human
Inhibition of the influenza virus RNA-dependent RNA polymerase by antisera directed against the carboxy-terminal region of the PB2 subunit.
Influenza, Human
Inhibition of the particle-associated RNA-dependent RNA polymerase activity of influenza viruses by chelating agents.
Influenza, Human
Inhibition of the protease activity of influenza virus RNA polymerase PA subunit by viral matrix protein.
Influenza, Human
Inhibition of transcriptase activity of influenza A virus in vitro by anti-haemagglutinin antibodies.
Influenza, Human
Inhibitory effect of modified 5'-capped short RNA fragments on influenza virus RNA polymerase gene expression.
Influenza, Human
Initiation, elongation and realignment during influenza virus mRNA synthesis.
Influenza, Human
Interaction between anti-influenza viral polymerase antibodies and RNP particles using the in vitro transcription process and an immunogold labelling technique.
Influenza, Human
Interaction of Host Nucleolin with Influenza A Virus Nucleoprotein in the Early Phase of Infection Limits the Late Viral Gene Expression.
Influenza, Human
Interaction of the influenza a virus nucleocapsid protein with the viral RNA polymerase potentiates unprimed viral RNA replication.
Influenza, Human
Interactions between the influenza A virus RNA polymerase components and retinoic acid-inducible gene I.
Influenza, Human
Interactome Analysis of NS1 Protein Encoded by Influenza A H7N9 Virus Reveals an Inhibitory Role of NS1 in Host mRNA Maturation.
Influenza, Human
Interactome analysis of the influenza A virus transcription/replication machinery identifies protein phosphatase 6 as a cellular factor required for efficient virus replication.
Influenza, Human
Internal initiation of influenza virus replication of v- and cRNA in vitro.
Influenza, Human
Interplay between Influenza Virus and the Host RNA Polymerase II Transcriptional Machinery.
Influenza, Human
Introduction of site-specific mutations into the genome of influenza virus.
Influenza, Human
Investigation of Binding Affinity between Potential Antiviral Agents and PB2 Protein of Influenza A: Non-equilibrium Molecular Dynamics Simulation Approach.
Influenza, Human
Investigation of recombinants of human influenza and fowl plague viruses.
Influenza, Human
Involvement of Hsp90 in assembly and nuclear import of influenza virus RNA polymerase subunits.
Influenza, Human
Involvement of influenza virus PA subunit in assembly of functional RNA polymerase complexes.
Influenza, Human
Involvement of the N-terminal portion of influenza virus RNA polymerase subunit PB1 in nucleotide recognition.
Influenza, Human
In vitro antiviral effects of Peganum harmala seed extract and its total alkaloids against Influenza virus.
Influenza, Human
Is oseltamivir suitable for fighting against COVID-19: In silico assessment, in vitro and retrospective study.
Influenza, Human
Isolation and characterization of cytoplasmic inclusions from influenza A virus-infected cells.
Influenza, Human
Isolation and characterization of the positive-sense replicative intermediate of a negative-strand RNA virus.
Influenza, Human
Isolation and properties of a temperature-sensitive mutant (ts 412) of an influenza A virus recombinant with a ts lesion in the gene coding for the nonstructural protein.
Influenza, Human
Isolation and properties of an RNA polymerase from influenza virus-infected cells.
Influenza, Human
Key role of regulated upon activation normal T-cell expressed and secreted, nonstructural protein1 and myeloperoxidase in cytokine storm induced by influenza virus PR-8 (A/H1N1) infection in A549 bronchial epithelial cells.
Influenza, Human
La Crosse virus nonstructural protein NSs counteracts the effects of short interfering RNA.
Influenza, Human
Large-Scale Conformational Dynamics Control H5N1 Influenza Polymerase PB2 Binding to Importin ?.
Influenza, Human
Learning from our foes: a novel vaccine concept for influenza virus.
Influenza, Human
Limited compatibility between the RNA polymerase components of influenza virus type A and B.
Influenza, Human
Mapping of functional domains on the influenza A virus RNA polymerase PB2 molecule using monoclonal antibodies.
Influenza, Human
Mapping of the influenza virus genome. III. Identification of genes coding for nucleoprotein, membrane protein, and nonstructural protein.
Influenza, Human
Mapping the domain structure of the influenza A virus polymerase acidic protein (PA) and its interaction with the basic protein 1 (PB1) subunit.
Influenza, Human
Mechanism for inhibition of influenza virus RNA polymerase activity by matrix protein.
Influenza, Human
Mechanism of action of T-705 against influenza virus.
Influenza, Human
Mechanism of action of T-705 ribosyl triphosphate against influenza virus RNA polymerase.
Influenza, Human
Mesoionic heterocyclic compounds as candidate messenger RNA cap analogue inhibitors of the influenza virus RNA polymerase cap-binding activity.
Influenza, Human
Messenger RNAs that are not synthesized by RNA polymerase II can be 3' end cleaved and polyadenylated.
Influenza, Human
Metal ion catalysis of RNA cleavage by the influenza virus endonuclease.
Influenza, Human
Minimum molecular architectures for transcription and replication of the influenza virus.
Influenza, Human
Mode of interference of trisodium phosphonoformate (INN: foscarnet sodium), with influenza virus mRNA synthesis.
Influenza, Human
Mode of replication and temperature characteristics of the RNA polymerase of an influenza virus in vitro.
Influenza, Human
Model suggesting that replication of influenza virus is regulated by stabilization of replicative intermediates.
Influenza, Human
Modulation of mRNA Translation and Cell Viability by Influenza A Virus Derived Nonstructural Protein 1.
Influenza, Human
Molecular assembly of the influenza virus RNA polymerase: determination of the subunit-subunit contact sites.
Influenza, Human
Molecular basis of the interaction for an essential subunit PA-PB1 in influenza virus RNA polymerase: insights from molecular dynamics simulation and free energy calculation.
Influenza, Human
Molecular dissection of influenza virus RNA polymerase: PB1 subunit alone is able to catalyze RNA synthesis.
Influenza, Human
Molecular mapping of influenza virus RNA polymerase by site-specific antibodies.
Influenza, Human
Molecular Mechanisms of Tight Binding through Fuzzy Interactions.
Influenza, Human
mRNA 5'-cap binding activity in purified influenza virus detected by simple, rapid assay.
Influenza, Human
Multiple amino acid mutations in viral RNA polymerase may synergistically enhance the transmissibility and/or virulence of the 2009 pandemic influenza (H1N1) virus.
Influenza, Human
Multiplex assay for simultaneously typing and subtyping influenza viruses by use of an electronic microarray.
Influenza, Human
Mutated influenza A virus exhibiting reduced susceptibility to baloxavir marboxil from an experimentally infected horse.
Influenza, Human
Mutation in NS2, a nonstructural protein of influenza A virus, extragenically causes aberrant replication and expression of the PA gene and leads to generation of defective interfering particles.
Influenza, Human
Mutation of an Influenza Virus Polymerase 3' RNA Promoter Binding Site Inhibits Transcription Elongation.
Influenza, Human
Mutational analyses of the influenza A virus polymerase subunit PA reveal distinct functions related and unrelated to RNA polymerase activity.
Influenza, Human
Mutational analysis of influenza B virus RNA transcription in vitro.
Influenza, Human
Mutational analysis of influenza virus promoter elements in vivo.
Influenza, Human
Mutational analysis of the conserved motifs of influenza A virus polymerase basic protein 1.
Influenza, Human
Mutational analysis of the influenza virus A/Victoria/3/75 PA protein: studies of interaction with PB1 protein and identification of a dominant negative mutant.
Influenza, Human
Mutations in influenza virus replication and transcription: detection of amino acid substitutions in hemagglutinin of an avian influenza virus (H1N1).
Influenza, Human
Mutations in the NS1 protein of swine influenza virus impair anti-interferon activity and confer attenuation in pigs.
Influenza, Human
N-Glycans attached to the stem domain of haemagglutinin efficiently regulate influenza A virus replication.
Influenza, Human
Naturally occurring mutations in PB1 affect influenza A virus replication fidelity, virulence, and adaptability.
Influenza, Human
New Insight into Metal Ion-Driven Catalysis of Nucleic Acids by Influenza PA-Nter.
Influenza, Human
New insights into antiviral and cytotoxic potential of quercetin and its derivatives - A biochemical perspective.
Influenza, Human
NMR spectra of PB2 627, the RNA-binding domain in influenza A virus RNA polymerase that contains the pathogenicity factor lysine 627, and improvement of the spectra by small osmolytes.
Influenza, Human
Non-structural protein 1 of influenza viruses inhibits rapid mRNA degradation mediated by double-stranded RNA-binding protein, staufen1.
Influenza, Human
Non-Uniform and Non-Random Binding of Nucleoprotein to Influenza A and B Viral RNA.
Influenza, Human
Nonstructural protein 1 of influenza A virus interacts with human guanylate-binding protein 1 to antagonize antiviral activity.
Influenza, Human
NS1 protein of influenza A virus inhibits the function of intracytoplasmic pathogen sensor, RIG-I.
Influenza, Human
NS1-Truncated Live Attenuated Virus Vaccine Provides Robust Protection to Aged Mice from Viral Challenge.
Influenza, Human
NS2 protein of influenza virus is found in purified virus and phosphorylated in infected cells.
Influenza, Human
Nuclear and nucleolar targeting of influenza A virus NS1 protein: striking differences between different virus subtypes.
Influenza, Human
Nuclear dynamics of influenza A virus ribonucleoproteins revealed by live-cell imaging studies.
Influenza, Human
Nuclear import and assembly of influenza A virus RNA polymerase studied in live cells by fluorescence cross-correlation spectroscopy.
Influenza, Human
Nuclear localization of influenza B polymerase proteins and their binary complexes.
Influenza, Human
Nuclear localized Influenza nucleoprotein N-terminal deletion mutant is deficient in functional vRNP formation.
Influenza, Human
Nuclear location of all three influenza polymerase proteins and a nuclear signal in polymerase PB2.
Influenza, Human
Nuclear MxA proteins form a complex with influenza virus NP and inhibit the transcription of the engineered influenza virus genome.
Influenza, Human
Nuclear transport of influenza virus polymerase PA protein.
Influenza, Human
Nucleotides in the panhandle structure of the influenza B virus virion RNA are involved in the specificity between influenza A and B viruses.
Influenza, Human
Oncolytic activity of a novel influenza A virus carrying GM-CSF in hepatocellular carcinoma.
Influenza, Human
Open-label study of the safety, pharmacokinetics, and effectiveness of a 2 mg/kg dose of baloxavir marboxil 2% granules in children <20 kg with influenza.
Influenza, Human
Optimizing antiviral therapy for influenza: understanding the evidence.
Influenza, Human
PA subunit of RNA polymerase as a promising target for anti-influenza virus agents.
Influenza, Human
Phenyl substituted 3-hydroxypyridin-2(1H)-ones: Inhibitors of influenza A endonuclease.
Influenza, Human
Phenyl substituted 4-hydroxypyridazin-3(2H)-ones and 5-hydroxypyrimidin-4(3H)-ones: inhibitors of influenza A endonuclease.
Influenza, Human
Phosphorylation of Influenza A Virus NS1 at Serine 205 Mediates Its Viral Polymerase-Enhancing Function.
Influenza, Human
Photoaffinity labeling of influenza virus RNA polymerase PB1 subunit with 8-azido GTP.
Influenza, Human
Polycistronic Expression of the Influenza A Virus RNA-Dependent RNA Polymerase by Using the Thosea asigna Virus 2A-Like Self-Processing Sequence.
Influenza, Human
Polyuridylated mRNA synthesized by a recombinant influenza virus is defective in nuclear export.
Influenza, Human
Possibility of cross-species/subtype reassortments in influenza A viruses: An analysis on nonstructural protein variations.
Influenza, Human
Potent and broad-spectrum cycloheptathiophene-3-carboxamide compounds that target the PA-PB1 interaction of influenza virus RNA polymerase and possess a high barrier to drug resistance.
Influenza, Human
Potential role of zinc supplementation in prophylaxis and treatment of COVID-19.
Influenza, Human
pp32 and APRIL are host cell-derived regulators of influenza virus RNA synthesis from cRNA.
Influenza, Human
Pre-mRNA Processing Factor Prp18 Is a Stimulatory Factor of Influenza Virus RNA Synthesis and Possesses Nucleoprotein Chaperone Activity.
Influenza, Human
Precise prediction of a Kk-restricted cytotoxic T cell epitope in the NS1 protein of influenza virus using an MHC allele-specific motif.
Influenza, Human
Preferential use of RNA leader sequences during influenza A transcription initiation in vivo.
Influenza, Human
Presence of genomic polyadenylate and absence of detectable virion transcriptase in human coronavirus OC-43.
Influenza, Human
Priming and inhibitory activities of RNAs for the influenza viral transcriptase do not require base pairing with the virion template RNA.
Influenza, Human
Priming and realignment by the influenza a virus RdRp is dependent on the length of the host primers and the extent of base pairing to viral RNA.
Influenza, Human
Probing the impact of quercetin-7-O-glucoside on influenza virus replication influence.
Influenza, Human
Promoter analysis of influenza virus RNA polymerase.
Influenza, Human
Proofreading function associated with the RNA-dependent RNA polymerase from influenza virus.
Influenza, Human
Properties of an RNA polymerase complex detected in influenza virus-infected cells.
Influenza, Human
Prostate tumor cells infected with a recombinant influenza virus expressing a truncated NS1 protein activate cytolytic CD8+ cells to recognize noninfected tumor cells.
Influenza, Human
Protective cross-reactive epitope on the nonstructural protein NS1 of influenza A virus.
Influenza, Human
Protective Immunity Against Homologous and Heterologous Influenza Virus Lethal Challenge by Immunization with New Recombinant Chimeric HA2-M2e Fusion Protein in BALB/C Mice.
Influenza, Human
Protocol: transmission and prevention of influenza in Hutterites: zoonotic transmission of influenza A: swine & swine workers.
Influenza, Human
Purification and molecular structure of RNA polymerase from influenza virus A/PR8.
Influenza, Human
Purification, thioredoxin renaturation, and reconstituted activity of the three subunits of the influenza A virus RNA polymerase.
Influenza, Human
Real-time analysis of single influenza virus replication complexes reveals large promoter-dependent differences in initiation dynamics.
Influenza, Human
Rearrangement of Influenza Virus Spliced Segments for the Development of Live-Attenuated Vaccines.
Influenza, Human
Reassortant Eurasian Avian-Like Influenza A(H1N1) Virus from a Severely Ill Child, Hunan Province, China, 2015.
Influenza, Human
Recognition of cap structure by influenza B virus RNA polymerase is less dependent on the methyl residue than recognition by influenza A virus polymerase.
Influenza, Human
Recombinant influenza virus polymerase: requirement of both 5' and 3' viral ends for endonuclease activity.
Influenza, Human
Recombinant-baculovirus-expressed PB2 subunit of the influenza A virus RNA polymerase binds cap groups as an isolated subunit.
Influenza, Human
Reconstitution of human rRNA gene transcription in mouse cells by a complete SL1 complex.
Influenza, Human
Reconstitution of influenza virus RNA polymerase from three subunits expressed using recombinant baculovirus system.
Influenza, Human
Recruitment of RED-SMU1 complex by Influenza A Virus RNA polymerase to control Ciral mRNA splicing.
Influenza, Human
Regulation of eukaryotic protein synthesis: selective influenza viral mRNA translation is mediated by the cellular RNA-binding protein GRSF-1.
Influenza, Human
Regulation of Influenza RNA Polymerase Activity and the Switch between Replication and Transcription by the Concentrations of the vRNA 5' End, the Cap Source, and of the Polymerase.
Influenza, Human
Regulation of influenza virus RNA polymerase activity by cellular and viral factors.
Influenza, Human
Relationship between the RNA polymerase activities from influenza virions and influenza virus-infected cells.
Influenza, Human
Replication and transcription activities of ribonucleoprotein complexes reconstituted from avian H5N1, H1N1pdm09 and H3N2 influenza A viruses.
Influenza, Human
Replication in vitro of the influenza virus genome: selective dissociation of RNA replicase from virus-infected cell ribonucleoprotein complexes.
Influenza, Human
Replication-coupled and host factor-mediated encapsidation of the influenza virus genome by viral nucleoprotein.
Influenza, Human
Rescue of a synthetic chloramphenicol acetyltransferase RNA into influenza virus-like particles obtained from recombinant plasmids.
Influenza, Human
RNA ligands activate the Machupo virus polymerase and guide promoter usage.
Influenza, Human
RNA Modulates the Interaction between Influenza A Virus NS1 and Human PABP1.
Influenza, Human
RNA polymerase I-mediated expression of influenza viral RNA molecules.
Influenza, Human
RNA polymerase of influenza virus. Dinucleotide-primed initiation of transcription at specific positions on viral RNA.
Influenza, Human
RNA polymerase of influenza virus. I. Comparison of the virion-associated RNA polymerase activity of various strains of influenza virus.
Influenza, Human
RNA polymerase of influenza virus. II. Influence of oligonucleotide chain length on the priming activity of RNA synthesis by virion-associated RNA polymerase.
Influenza, Human
RNA polymerase of influenza virus. III. Isolation of RNA polymerase-RNA complexes from influenza virus PR8.
Influenza, Human
RNA polymerase of influenza virus. IV. Catalytic properties of the capped RNA endonuclease associated with the RNA polymerase.
Influenza, Human
RNA polymerase of influenza virus: role of NP in RNA chain elongation.
Influenza, Human
RNA-binding properties of influenza A virus matrix protein M1.
Influenza, Human
RNA-dependent activation of primer RNA production by influenza virus polymerase: different regions of the same protein subunit constitute the two required RNA-binding sites.
Influenza, Human
RNA-dependent RNA polymerase activity in influenza virions.
Influenza, Human
RNA-dependent RNA polymerase activity of the influenza virus.
Influenza, Human
RNA-dependent RNA polymerase in nuclei of cells infected with influenza virus.
Influenza, Human
RNA-Free and Ribonucleoprotein-Associated Influenza Virus Polymerases Directly Bind the Serine-5-Phosphorylated Carboxyl-Terminal Domain of Host RNA Polymerase II.
Influenza, Human
RNase-like domain in DNA-directed RNA polymerase II.
Influenza, Human
Role of host protein Ebp1 in influenza virus growth: intracellular localization of Ebp1 in virus-infected and uninfected cells.
Influenza, Human
Role of human hypoxanthine Guanine phosphoribosyltransferase in activation of the antiviral agent T-705 (favipiravir).
Influenza, Human
Role of initiating nucleoside triphosphate concentrations in the regulation of influenza virus replication and transcription.
Influenza, Human
Role of ran binding protein 5 in nuclear import and assembly of the influenza virus RNA polymerase complex.
Influenza, Human
Role of TGF-?-activated kinase 1 (TAK1) activation in H5N1 influenza A virus-induced c-Jun terminal kinase activation and virus replication.
Influenza, Human
Role of the influenza virus heterotrimeric RNA polymerase complex in the initiation of replication.
Influenza, Human
Role of the PB2 627 Domain in Influenza A Virus Polymerase Function.
Influenza, Human
Safety and immunogenicity of a recombinant protein influenza A vaccine in adult human volunteers and protective efficacy against wild-type H1N1 virus challenge.
Influenza, Human
SAR Exploration of Tight Binding Inhibitors of Influenza Virus PA Endonuclease.
Influenza, Human
SARS-CoV-2 and influenza: a comparative overview and treatment implications.
Influenza, Human
SARS-CoV-2 Nucleocapsid Protein Targets RIG-I-Like Receptor Pathways to Inhibit the Induction of Interferon Response.
Influenza, Human
Schizophrenia Susceptibility Genes Directly Implicated in the Life Cycles of Pathogens: Cytomegalovirus, Influenza, Herpes simplex, Rubella, and Toxoplasma gondii.
Influenza, Human
Screen Anti-influenza Lead Compounds That Target the PA(C) Subunit of H5N1 Viral RNA Polymerase.
Influenza, Human
Screening for Novel Small-Molecule Inhibitors Targeting the Assembly of Influenza Virus Polymerase Complex by a Bimolecular Luminescence Complementation-Based Reporter System.
Influenza, Human
Sequence-specific binding of the influenza virus RNA polymerase to sequences located at the 5' ends of the viral RNAs.
Influenza, Human
Ser624 of the PA subunit of influenza A virus is not essential for viral growth in cells and mice, but required for the maximal viral growth.
Influenza, Human
Single-molecule FRET reveals a corkscrew RNA structure for the polymerase-bound influenza virus promoter.
Influenza, Human
Single-molecule FRET reveals the pre-initiation and initiation conformations of influenza virus promoter RNA.
Influenza, Human
Small interfering RNA targeting the nonstructural gene 1 transcript inhibits influenza A virus replication in experimental mice.
Influenza, Human
Small molecule inhibitors of influenza A and B viruses that act by disrupting subunit interactions of the viral polymerase.
Influenza, Human
Small Variations Between Species/Subtypes Attributed to Reassortment Evidenced from Polymerase Basic Protein 1 with Other Seven Proteins from Influenza A Virus.
Influenza, Human
Solid phase synthesis of 5'-diphosphorylated oligoribonucleotides and their conversion to capped m7Gppp-oligoribonucleotides for use as primers for influenza A virus RNA polymerase in vitro.
Influenza, Human
Solution structure of the influenza A virus cRNA promoter: implications for differential recognition of viral promoter structures by RNA-dependent RNA polymerase.
Influenza, Human
Specific binding of influenza A virus NS1 protein to the virus minus-sense RNA in vitro.
Influenza, Human
Specific inhibition of influenza virus RNA polymerase and nucleoprotein gene expression by circular dumbbell RNA/DNA chimeric oligonucleotides containing antisense phosphodiester oligonucleotides.
Influenza, Human
Specific inhibition of influenza virus RNA polymerase and nucleoprotein gene expression by liposomally encapsulated antisense phosphorothioate oligonucleotides in MDCK cells.
Influenza, Human
Specific inhibition of influenza virus RNA polymerase and nucleoprotein genes expression by liposomally endocapsulated antisense phosphorothioate oligonucleotides: penetration and localization of oligonucleotides in clone 76 cells.
Influenza, Human
Stabilization of influenza virus replication intermediates is dependent on the RNA-binding but not the homo-oligomerization activity of the viral nucleoprotein.
Influenza, Human
Structural and Biochemical Analyses on the RNA-dependent RNA Polymerase of Influenza Virus for Development of Novel Anti-influenza Agents.
Influenza, Human
Structural and computational study on inhibitory compounds for endonuclease activity of influenza virus polymerase.
Influenza, Human
Structural and Functional Characterization of K339T Substitution Identified in the PB2 Cap-binding Pocket of Influenza A Virus.
Influenza, Human
Structural basis for dsRNA recognition by NS1 protein of influenza A virus.
Influenza, Human
Structural basis of the influenza A virus RNA polymerase PB2 RNA-binding domain containing the pathogenicity-determinant lysine 627 residue.
Influenza, Human
Structural characterization of recombinant IAV polymerase reveals a stable complex between viral PA-PB1 heterodimer and host RanBP5.
Influenza, Human
structural characterization of the interaction between the C-terminal domain of the influenza polymerase PA subunit and an optimized small peptide inhibitor.
Influenza, Human
Structural features of an influenza virus promoter and their implications for viral RNA synthesis.
Influenza, Human
Structural insight into the essential PB1-PB2 subunit contact of the influenza virus RNA polymerase.
Influenza, Human
Structural insights into the substrate specificity of the endonuclease activity of the influenza virus cap-snatching mechanism.
Influenza, Human
Structural Mapping of Mutations in Spike, RdRp and Orf3a Genes of SARS-CoV-2 in Influenza Like Illness (ILI) Patients.
Influenza, Human
Structural snapshots of actively transcribing influenza polymerase.
Influenza, Human
Structure and Function of the Influenza Virus Transcription and Replication Machinery.
Influenza, Human
Structure and Sequence Determinants Governing the Interactions of RNAs with Influenza A Virus Non-Structural Protein NS1.
Influenza, Human
Structure of NS1A effector domain from the influenza A/Udorn/72 virus.
Influenza, Human
Structure of the iSH2 domain of human phosphatidylinositol 3-kinase p85? subunit reveals conformational plasticity in the interhelical turn region.
Influenza, Human
Structure of the L Protein of Vesicular Stomatitis Virus from Electron Cryomicroscopy.
Influenza, Human
Structure resolution of the trimeric RNA-dependent RNA polymerase of influenza viruses: impact on our understanding of polymerase interactions with host and viral factors.
Influenza, Human
Structure-Activity Relationships in Metal-Binding Pharmacophores for Influenza Endonuclease.
Influenza, Human
Structure-based virtual screening of influenza virus RNA polymerase inhibitors from natural compounds: Molecular dynamics simulation and MM-GBSA calculation.
Influenza, Human
Structure-function relationship of the influenza virus RNA polymerase: primer-binding site on the PB1 subunit.
Influenza, Human
Structure-function studies of the influenza virus RNA polymerase PA subunit.
Influenza, Human
Structures of influenza A proteins and insights into antiviral drug targets.
Influenza, Human
Structures of influenza A virus RNA polymerase offer insight into viral genome replication.
Influenza, Human
Studies of an influenza A virus temperature-sensitive mutant identify a late role for NP in the formation of infectious virions.
Influenza, Human
Studies of proteins soluble in acidic chloroform-methanol isolated from crude human leukocyte interferon preparations.
Influenza, Human
Studies of the Interaction of Influenza Virus RNA Polymerase PAN with Endonuclease Inhibitors.
Influenza, Human
Studies on the mechanism of neutralization of influenza virus by antibody: evidence that neutralizing antibody (anti-haemagglutinin) inactivates influenza virus in vivo by inhibiting virion transcriptase activity.
Influenza, Human
Studies on the synthesis of the influenza V virus NB glycoprotein.
Influenza, Human
Sublingual immunization with a live attenuated influenza a virus lacking the nonstructural protein 1 induces broad protective immunity in mice.
Influenza, Human
Surface expression of a nonstructural antigen on influenza A virus-infected cells.
Influenza, Human
Synergistic adaptive mutations in the hemagglutinin and polymerase acidic protein lead to increased virulence of pandemic 2009 H1N1 influenza A virus in mice.
Influenza, Human
Synthesis and antiviral activity of PB1 component of the influenza A RNA polymerase peptide fragments.
Influenza, Human
Synthesis and Antiviral Evaluation of Nucleoside Analogues Bearing One Pyrimidine Moiety and Two D-Ribofuranosyl Residues.
Influenza, Human
Synthesis and biological evaluation of pyrimidine nucleoside monophosphate prodrugs targeted against influenza virus.
Influenza, Human
Synthesis and In Vitro Evaluation of C-7 and C-8 Luteolin Derivatives as Influenza Endonuclease Inhibitors.
Influenza, Human
Synthesis and inhibitory effects of novel pyrimido-pyrrolo-quinoxalinedione analogues targeting nucleoproteins of influenza A virus H1N1.
Influenza, Human
Synthesis and pharmacological studies of some (1,4)-naphthoquinono[3,2-c]-1H-pyrazoles, 2-substituted amino-1,4-naphthoquinones, and related compounds.
Influenza, Human
Synthesis in vitro of RNA complementary to parental viral RNA by RNA polymerase induced by influenza virus.
Influenza, Human
Synthesis of 1,2,3-triazolyl nucleoside analogues and their antiviral activity.
Influenza, Human
Synthesis of a Novel Class of 1,3-oxathiolane Nucleoside Derivatives of T-705 and Evaluation of Their Anti-influenza A Virus and Anti-HIV Activity.
Influenza, Human
Synthesis of adenylyl-(3'----5')-guanosine and some analogues as probes to explore the molecular mechanism of stimulation of influenza virus RNA polymerase.
Influenza, Human
Synthesis of biologically active influenza virus core proteins using a vaccinia virus-T7 RNA polymerase expression system.
Influenza, Human
Synthesis of the NS 2 nonstructural protein messenger RNA of influenza A viruses occurs in the absence of viral protein synthesis.
Influenza, Human
T-705 (favipiravir) and related compounds: Novel broad-spectrum inhibitors of RNA viral infections.
Influenza, Human
T-705 (Favipiravir) Induces Lethal Mutagenesis in Influenza A H1N1 Viruses In Vitro.
Influenza, Human
Temperature sensitive influenza A virus genome replication results from low thermal stability of polymerase-cRNA complexes.
Influenza, Human
Temperature Sensitive Mutations in Influenza A Viral Ribonucleoprotein Complex Responsible for the Attenuation of the Live Attenuated Influenza Vaccine.
Influenza, Human
Temperature-Sensitive Mutants in the Influenza A Virus RNA Polymerase: Alterations in the PA Linker Reduce Nuclear Targeting of the PB1-PA Dimer and Result in Viral Attenuation.
Influenza, Human
Temperature-sensitive virion transcriptase activity in mutants of WSN influenza virus.
Influenza, Human
The active sites of the influenza cap-dependent endonuclease are on different polymerase subunits.
Influenza, Human
The antiviral activity of tetrazole phosphonic acids and their analogues.
Influenza, Human
The biology of influenza viruses.
Influenza, Human
The broad spectrum antiviral ivermectin targets the host nuclear transport importin ?/?1 heterodimer.
Influenza, Human
The cap-binding site of influenza virus protein PB2 as a drug target.
Influenza, Human
The Crystal Structure of the PB2 Cap-binding Domain of Influenza B Virus Reveals a Novel Cap Recognition Mechanism.
Influenza, Human
The Current Recommended Drugs and Strategies for the Treatment of Coronavirus Disease (COVID-19).
Influenza, Human
The detection and characterization of an induced RNA polymerase in the chorioallantoic membranes of embryonated eggs infected with influenza A2 virus.
Influenza, Human
The Drift in Molecular Testing for Influenza: Mutations Affecting Assay Performance.
Influenza, Human
The effect of pyrophosphate analogues on influenza virus RNA polymerase and influenza virus multiplication.
Influenza, Human
The Effector Domain of the Influenza A Virus Nonstructural Protein NS1 Triggers Host Shutoff by Mediating Inhibition and Global Deregulation of Host Transcription When Associated with Specific Structures in the Nucleus.
Influenza, Human
The effects of NS gene exchange on the pathogenicity of H5N1 HPAI viruses in ducks.
Influenza, Human
The fight against the influenza A virus H1N1: synthesis, molecular modeling, and biological evaluation of benzofurazan derivatives as viral RNA polymerase inhibitors.
Influenza, Human
The fourth genus in the Orthomyxoviridae: sequence analyses of two Thogoto virus polymerase proteins and comparison with influenza viruses.
Influenza, Human
The Homologous Tripartite Viral RNA Polymerase of A/Swine/Korea/CT1204/2009(H1N2) Influenza Virus Synergistically Drives Efficient Replication and Promotes Respiratory Droplet Transmission in Ferrets.
Influenza, Human
The in vitro stimulation of the influenza transcriptase by ribosomes.
Influenza, Human
The influenza A virus proteins PB1 and NS1 are subject to functionally important phosphorylation by protein kinase C.
Influenza, Human
The influenza NS1 protein modulates RIG-I activation via a strain-specific direct interaction with the second CARD of RIG-I.
Influenza, Human
The influenza virus NS1 protein as a therapeutic target.
Influenza, Human
The influenza virus nucleoprotein: a multifunctional RNA-binding protein pivotal to virus replication.
Influenza, Human
The influenza virus panhandle is involved in the initiation of transcription.
Influenza, Human
The influenza virus PB1-F2 protein has interferon antagonistic activity.
Influenza, Human
The influenza virus RNA synthesis machine: Advances in its structure and function.
Influenza, Human
The inhibition of the RNA polymerase activity of influenza virus A by pyrophosphate analogues.
Influenza, Human
The interaction of cellular protein ANP32A with influenza A virus polymerase component PB2 promotes vRNA synthesis.
Influenza, Human
The matrix 1 protein of influenza A virus inhibits the transcriptase activity of a model influenza reporter genome in vivo.
Influenza, Human
The mechanism of action of T-705 as a unique delayed chain terminator on influenza viral polymerase transcription.
Influenza, Human
The mechanism of resistance to favipiravir in influenza.
Influenza, Human
The molecular anatomy of influenza virus RNA polymerase.
Influenza, Human
The N-terminal extension of the influenza B virus nucleoprotein is not required for nuclear accumulation or the expression and replication of a model RNA.
Influenza, Human
The N-terminal fragment of a PB2 subunit from the influenza A virus (A/Hong Kong/156/1997 H5N1) effectively inhibits RNP activity and viral replication.
Influenza, Human
The N-terminal region of influenza virus polymerase PB1 adjacent to the PA binding site is involved in replication but not transcription of the viral genome.
Influenza, Human
The N-terminal region of the PA subunit of the RNA polymerase of influenza A/HongKong/156/97 (H5N1) influences promoter binding.
Influenza, Human
The N-terminal residual arginine19 of influenza A virus NS1 protein is required for its nuclear localization and RNA binding.
Influenza, Human
The novel mitochondria localization of influenza A virus NS1 visualized by FlAsH labeling.
Influenza, Human
The NS2/NEP Protein Regulates Transcription and Replication of the Influenza Virus RNA Genome.
Influenza, Human
The ORF, regulated synthesis, and persistence-specific variation of influenza C viral NS1 protein.
Influenza, Human
The PA influenza virus polymerase subunit is a phosphorylated protein.
Influenza, Human
The PA subunit is required for efficient nuclear accumulation of the PB1 subunit of the influenza A virus RNA polymerase complex.
Influenza, Human
The PB1 subunit alone can catalyze cRNA synthesis, and the PA subunit in addition to the PB1 subunit is required for viral RNA synthesis in replication of the influenza virus genome.
Influenza, Human
The PB2 Subunit of the Influenza A Virus RNA Polymerase Is Imported into the Mitochondrial Matrix.
Influenza, Human
The PB2 subunit of the influenza virus RNA polymerase affects virulence by interacting with the mitochondrial antiviral signaling protein and inhibiting expression of beta interferon.
Influenza, Human
The Polymerase Acidic Protein Gene of Influenza A Virus Contributes to Pathogenicity in a Mouse Model.
Influenza, Human
The putative polymerase sequence of infectious salmon anemia virus suggests a new genus within the Orthomyxoviridae.
Influenza, Human
The RNA polymerase of influenza a virus is stabilized by interaction with its viral RNA promoter.
Influenza, Human
The RNA polymerase of influenza a virus: mechanisms of viral transcription and replication.
Influenza, Human
The RNA polymerase of influenza virus, bound to the 5' end of virion RNA, acts in cis to polyadenylate mRNA.
Influenza, Human
The RNA polymerase PB2 subunit is not required for replication of the influenza virus genome but is involved in capped mRNA synthesis.
Influenza, Human
The RNA Polymerase PB2 Subunit of Influenza A/HongKong/156/1997 (H5N1) Restrict the Replication of Reassortant Ribonucleoprotein Complexes.
Influenza, Human
The RNA- and TRIM25-Binding Domains of Influenza Virus NS1 Protein Are Essential for Suppression of NLRP3 Inflammasome-Mediated Interleukin-1? Secretion.
Influenza, Human
The RNA-dependent RNA polymerase of the influenza A virus.
Influenza, Human
The role and assembly mechanism of nucleoprotein in influenza A virus ribonucleoprotein complexes.
Influenza, Human
The role of the influenza virus RNA polymerase in host shut-off.
Influenza, Human
The role of the priming loop in Influenza A virus RNA synthesis.
Influenza, Human
The role of the priming loop in influenza A virus RNA synthesis.
Influenza, Human
The splicing factor proline-glutamine rich (SFPQ/PSF) is involved in influenza virus transcription.
Influenza, Human
The structural basis for an essential subunit interaction in influenza virus RNA polymerase.
Influenza, Human
The structure and conformational plasticity of the nonstructural protein 1 of the 1918 influenza A virus.
Influenza, Human
The structure and synthesis of influenza virus phosphoproteins.
Influenza, Human
The Surface-Exposed PA51-72-Loop of the Influenza A Virus Polymerase Is Required for Viral Genome Replication.
Influenza, Human
The synthesis of polypeptides in influenza C virus-infected cells.
Influenza, Human
The tyrosine 73 and serine 83 dephosphorylation of H1N1 swine influenza virus NS1 protein attenuates virus replication and induces high levels of beta interferon.
Influenza, Human
The viral mechanism of Reye's syndrome.
Influenza, Human
Therapy of respiratory viral infections with intranasal siRNAs.
Influenza, Human
Three-dimensional model for the isolated recombinant influenza virus polymerase heterotrimer.
Influenza, Human
To Conquer the Host, Influenza Virus Is Packing It In: Interferon-Antagonistic Strategies beyond NS1.
Influenza, Human
Tools to detect influenza virus.
Influenza, Human
Toosendanin From Melia Fructus Suppresses Influenza A Virus Infection by Altering Nuclear Localization of Viral Polymerase PA Protein.
Influenza, Human
Transcriptase activity and genome composition of defective influenza virus.
Influenza, Human
Transcription of a recombinant influenza virus RNA in cells that can express the influenza virus RNA polymerase and nucleoprotein genes.
Influenza, Human
Transcription of the influenza ribonucleic acid genome by a virion polymerase. I. Optimal conditions for in vitro activity of the ribonucleic acid-dependent ribonucleic acid polymerase.
Influenza, Human
Transient bicistronic vRNA segments for indirect selection of recombinant influenza viruses.
Influenza, Human
Transient expression and sequence of the matrix (M1) gene of WSN influenza A virus in a vaccinia vector.
Influenza, Human
Translational control by influenza virus. Selective translation is mediated by sequences within the viral mRNA 5'-untranslated region.
Influenza, Human
Translational regulation of viral secretory proteins by the 5' coding regions and a viral RNA-binding protein.
Influenza, Human
Treatment-Emergent Influenza Variant Viruses With Reduced Baloxavir Susceptibility: Impact on Clinical and Virologic Outcomes in Uncomplicated Influenza.
Influenza, Human
TRIM32 Senses and Restricts Influenza A Virus by Ubiquitination of PB1 Polymerase.
Influenza, Human
Two aromatic residues in the PB2 subunit of influenza A RNA polymerase are crucial for cap binding.
Influenza, Human
Two Distinctive Binding Modes of Endonuclease Inhibitors to the N-Terminal Region of Influenza Virus Polymerase Acidic Subunit.
Influenza, Human
Two mutations in the C-terminal domain of influenza virus RNA polymerase PB2 enhance transcription by enhancing cap-1 RNA binding activity.
Influenza, Human
Two nuclear location signals in the influenza virus NS1 nonstructural protein.
Influenza, Human
Two separate sequences of PB2 subunit constitute the RNA cap-binding site of influenza virus RNA polymerase.
Influenza, Human
Type I interferon antagonistic properties of influenza B virus polymerase proteins.
Influenza, Human
Type-IInterferon-Inducible SERTAD3 Inhibits Influenza A Virus Replication by Blocking the Assembly of Viral RNA Polymerase Complex.
Influenza, Human
Tyr82 Amino Acid Mutation in PB1 Polymerase Induces an Influenza Virus Mutator Phenotype.
Influenza, Human
U4 at the 3' UTR of PB1 Segment of H5N1 Influenza Virus Promotes RNA Polymerase Activity and Contributes to Viral Pathogenicity.
Influenza, Human
Ultrastructure of influenza virus ribonucleoprotein complexes during viral RNA synthesis.
Influenza, Human
Uncoupling of Influenza A Virus Transcription and Replication through Mutation of the Unpaired Adenosine in the Viral RNA Promoter.
Influenza, Human
Understanding the Binding Transition State After the Conformational Selection Step: The Second Half of the Molecular Recognition Process Between NS1 of the 1918 Influenza Virus and Host p85?.
Influenza, Human
Unidirectional RNA polymerase I-polymerase II transcription system for the generation of influenza A virus from eight plasmids.
Influenza, Human
Unraveling the anti-influenza effect of flavonoids: Experimental validation of luteolin and its congeners as potent influenza endonuclease inhibitors.
Influenza, Human
Variation in ATP requirement during influenza virus transcription.
Influenza, Human
Variations outside the conserved motifs of PB1 catalytic active site may affect replication efficiency of the RNP complex of influenza A virus.
Influenza, Human
Viral RNA polymerase: a promising antiviral target for influenza a virus.
Influenza, Human
Viral Subpopulation Screening Guides in Designing a High Interferon-Inducing Live Attenuated Influenza Vaccine by Targeting Rare Mutations in NS1 and PB2 Proteins.
Influenza, Human
Virion transcriptase activity of influenza virus isolates.
Influenza, Human
Virion transcriptase activity of rimantadine-sensitive and rimantadine-resistant variants of human influenza virus.
Influenza, Human
Virion-associated transcriptase activity of influenza recombinant and mutant strains.
Influenza, Human
Virtual Screening and Biological Validation of Novel Influenza Virus PA Endonuclease Inhibitors.
Influenza, Human
Virucidal effect of sodium p-chloromercuribenzoate on influenza viruses attributable to inhibition of virus particle-associated RNA-dependent RNA polymerase.
Influenza, Human
Virus-encoded endonucleases: expected and novel functions.
Influenza, Human
Visualizing the beta interferon response in mice during infection with influenza A viruses expressing or lacking nonstructural protein 1.
Influenza, Human
What can we learn by computing 13Calpha chemical shifts for X-ray protein models?
Influenza, Human
X-ray structure of influenza virus NS1 effector domain.
Influenza, Human
X-ray structures of NS1 effector domain mutants.
Influenza, Human
[Activity of virion RNA-polymerase in influenza A and B virus variants with different pathogenicities for mice]
Influenza, Human
[Analysis of genetic variation of hemagglutinin and three internal genes of influenza B virus isolated in Zhejiang province from 1999 to 2012].
Influenza, Human
[Antisense nucleic acid therapy of influenza virus]
Influenza, Human
[Antiviral action of sodium selenite and its combination with remantadine]
Influenza, Human
[Characteristics of the structural organization and transcriptase activity of the influenza virus nucleoid]
Influenza, Human
[Characterization of RNA polymerase activity of highly purified preparations of influenza virus A/duck/Alberta/48/76]
Influenza, Human
[Comparative study of the RNA-polymerase activity of non-pathogenic and pathogenic influenza viruses A and B]
Influenza, Human
[Dynamics of the influenza virus genome regulated by cellular host factors].
Influenza, Human
[Effect of ribovirine (1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboximide) on RNA-dependent RNA-polymerase induction and virus-specific polysome formation in cell cultures infected with influenza A virus]
Influenza, Human
[Establishment of drug screening assay and pharmacodynamic evaluation method targeting influenza RNA polymerase].
Influenza, Human
[Function of influenza virus RNA polymerase based on structure]
Influenza, Human
[Functions of influenza virus RNA polymerase subunits]
Influenza, Human
[Influenza virus RNA polymerase]
Influenza, Human
[Inhibition of adenylyl-(3'--5') guanosine-stimulated virion RNA polymerase from influenza A virus by means of adenylyl-(3'--5') virazole]
Influenza, Human
[Inhibition of influenza virus A RNA-polymerase activity by various 3'-amino-3'-deoxy- and 3'-azido-3'-deoxyribonucleoside-5'-triphosphates]
Influenza, Human
[Inhibitory action of adenylyl-[3'--5']-ribavirin on the RNA polymerase activity of influenza A viruses]
Influenza, Human
[Inhibitory effect of 3'-azido-3'-azido-3'-deoxy- ribavirin-5'-triphosphate on RNA synthesis catalyzed by RNA polymerase from influenza A virus and by cellular DNA-dependent RNA polymerase II]
Influenza, Human
[Inhibitory effect of alpha-methyl-1-adamantane methylamine hydrochloride (rimantadine) on RNA-dependent RNA polymerase induction in culture of cells, infected with influenza virus]
Influenza, Human
[Inhibitory effect of deoxyadenylyl-(3'-5')-deoxyguanosine on the RNA-polymerase activity of influenza virus A]
Influenza, Human
[Inhibitory effect of various 3'-amino- and 3'-azido-3'-deoxyribonucleotide-5'-triphosphates on RNA synthesis, catalyzed by RNA polymerase of influenza type A virus and cellular RNA-polymerase]
Influenza, Human
[Molecular dissection of the influenza virus RNA polymerase]
Influenza, Human
[Present and future in a development of new anti-influenza drugs]
Influenza, Human
[Purification and function of RNA dependent RNA polymerase of an influenza virus]
Influenza, Human
[Recent advance in nonstructural protein of influenza virus A]
Influenza, Human
[Research progress in molecular determinants of neuraminidase, polymerase basic protein 2 and nonstructural protein 1, related to virulence of influenza A virus--a review].
Influenza, Human
[RNA transcriptase activity of a defective influenza virus]
Influenza, Human
[RNA-polymerase activity of pathogenic and nonpathogenic influenza A virus variants]
Influenza, Human
[Sequence analysis of NS1 gene of some H9N2 subtype influenza viruses isolated from chickens in China]
Influenza, Human
[Structural and functional aspects of influenza virus RNA polymerase]
Influenza, Human
[Structure-function relationship of the influenza virus RNA polymerase subunits]
Influenza, Human
[Structure-function relationship of the influenza virus RNA polymerase]
Influenza, Human
[The biological effects of coordination compounds of transitional metals. 6. Effect of 4-methyl-2-aminopyridine-palladium chloride and cis-dichlorodiammine-platinum(II) on retroviruses and the virus-associated RNA polymerase of the influenza virus]
Insulin Resistance
Advances in the role of HCV nonstructural protein 5a (NS5A) of 3a genotype in inducing insulin resistance by possible phosphorylation of AKT/PKB.
Insulin Resistance
Hepatitis C virus nonstructural protein 5A favors upregulation of gluconeogenic and lipogenic gene expression leading towards insulin resistance: a metabolic syndrome.
Insulin Resistance
Hepatitis C virus NS5A promotes insulin resistance through IRS-1 serine phosphorylation and increased gluconeogenesis.
Intellectual Disability
A conserved role for the zinc finger polyadenosine RNA binding protein, ZC3H14, in control of poly(A) tail length.
Intellectual Disability
A Genetic Screen Links the Disease-Associated Nab2 RNA-Binding Protein to the Planar Cell Polarity Pathway in Drosophila melanogaster.
Intellectual Disability
A human forebrain organoid model of fragile X syndrome exhibits altered neurogenesis and highlights new treatment strategies.
Intellectual Disability
A metabolomic and systems biology perspective on the brain of the fragile X syndrome mouse model.
Intellectual Disability
A mouse model of the human Fragile X syndrome I304N mutation.
Intellectual Disability
A new function for the fragile X mental retardation protein in regulation of PSD-95 mRNA stability.
Intellectual Disability
A novel function for fragile X mental retardation protein in translational activation.
Intellectual Disability
A novel role of fragile X mental retardation protein in pre-mRNA alternative splicing through RNA-binding protein 14.
Intellectual Disability
A nuclear role for the Fragile X mental retardation protein.
Intellectual Disability
Advances in understanding of fragile X pathogenesis and FMRP function, and in identification of X linked mental retardation genes.
Intellectual Disability
Altered mTOR signaling and enhanced CYFIP2 expression levels in subjects with fragile X syndrome.
Intellectual Disability
Analysis of FMRP mRNA target datasets reveals highly associated mRNAs mediated by G-quadruplex structures formed via clustered WGGA sequences.
Intellectual Disability
Biology of the fragile X mental retardation protein, an RNA-binding protein.
Intellectual Disability
Cells lacking the fragile X mental retardation protein (FMRP) have normal RISC activity but exhibit altered stress granule assembly.
Intellectual Disability
Characterization of fragile X mental retardation protein recruitment and dynamics in Drosophila stress granules.
Intellectual Disability
CYFIP family proteins between autism and intellectual disability: links with Fragile X syndrome.
Intellectual Disability
Decreased nociceptive sensitization in mice lacking the fragile X mental retardation protein: role of mGluR1/5 and mTOR.
Intellectual Disability
Delayed stabilization of dendritic spines in fragile X mice.
Intellectual Disability
Deletion of the KH1 Domain of Fmr1 Leads to Transcriptional Alterations and Attentional Deficits in Rats.
Intellectual Disability
Developmentally-programmed FMRP expression in oligodendrocytes: a potential role of FMRP in regulating translation in oligodendroglia progenitors.
Intellectual Disability
Differential regulation of BK channels by fragile X mental retardation protein.
Intellectual Disability
Discrimination of common and unique RNA-binding activities among Fragile X mental retardation protein paralogs.
Intellectual Disability
Dissecting FMR1, the protein responsible for fragile X syndrome, in its structural and functional domains.
Intellectual Disability
Dynamic Association of the Fragile X Mental Retardation Protein as a Messenger Ribonucleoprotein between Microtubules and Polyribosomes.
Intellectual Disability
Dynamics of the fragile X mental retardation protein correlates with cellular and synaptic properties in primary auditory neurons following afferent deprivation.
Intellectual Disability
Dysregulation and restoration of translational homeostasis in fragile X syndrome.
Intellectual Disability
Expression of MicroRNA machinery proteins in different types of chronic rhinosinusitis.
Intellectual Disability
FMRP acts as a key messenger for dopamine modulation in the forebrain.
Intellectual Disability
FMRP associates with polyribosomes as an mRNP, and the I304N mutation of severe fragile X syndrome abolishes this association.
Intellectual Disability
FMRP interferes with the Rac1 pathway and controls actin cytoskeleton dynamics in murine fibroblasts.
Intellectual Disability
FMRP phosphorylation reveals an immediate-early signaling pathway triggered by group I mGluR and mediated by PP2A.
Intellectual Disability
FMRP regulates miR196a-mediated repression of HOXB8 via interaction with the AGO2 MID domain.
Intellectual Disability
FMRP regulates neurogenesis in vivo in Xenopus laevis tadpoles.
Intellectual Disability
FMRP regulates the transition from radial glial cells to intermediate progenitor cells during neocortical development.
Intellectual Disability
FMRP targets distinct mRNA sequence elements to regulate protein expression.
Intellectual Disability
Fragile mental retardation protein interacts with the RNA-binding protein Caprin1 in neuronal RiboNucleoProtein complexes.
Intellectual Disability
Fragile X mental retardation protein (FMRP) and metabotropic glutamate receptor subtype 5 (mGlu5) control stress granule formation in astrocytes.
Intellectual Disability
Fragile X mental retardation protein (FMRP) binds specifically to the brain cytoplasmic RNAs BC1/BC200 via a novel RNA-binding motif.
Intellectual Disability
Fragile X mental retardation protein (FMRP) interacting proteins exhibit different expression patterns during development.
Intellectual Disability
Fragile X mental retardation protein controls gating of the sodium-activated potassium channel Slack.
Intellectual Disability
Fragile X mental retardation protein deficiency leads to excessive mGluR5-dependent internalization of AMPA receptors.
Intellectual Disability
Fragile X Mental Retardation protein determinants required for its association with polyribosomal mRNPs.
Intellectual Disability
Fragile X Mental Retardation Protein expression in the retina is regulated by light.
Intellectual Disability
Fragile X mental retardation protein induces synapse loss through acute postsynaptic translational regulation.
Intellectual Disability
Fragile X mental retardation protein is necessary for neurotransmitter-activated protein translation at synapses.
Intellectual Disability
Fragile X mental retardation protein is required for rapid experience-dependent regulation of the potassium channel Kv3.1b.
Intellectual Disability
Fragile X mental retardation protein is required for synapse elimination by the activity-dependent transcription factor MEF2.
Intellectual Disability
Fragile X mental retardation protein modulates the stability of its m6A-marked messenger RNA targets.
Intellectual Disability
Fragile X mental retardation protein regulates accumulation of the active zone protein Munc18-1 in presynapses via local translation in axons during synaptogenesis.
Intellectual Disability
Fragile X mental retardation protein regulates new neuron differentiation in the adult olfactory bulb.
Intellectual Disability
Fragile X mental retardation protein regulates olfactory sensitivity but not odorant discrimination.
Intellectual Disability
Fragile X mental retardation protein regulates synaptic and behavioral plasticity to repeated cocaine administration.
Intellectual Disability
Fragile X mental retardation protein shifts between polyribosomes and stress granules after neuronal injury by arsenite stress or in vivo hippocampal electrode insertion.
Intellectual Disability
Fragile X mental retardation protein-regulated proinflammatory cytokine expression in the spinal cord contributes to the pathogenesis of inflammatory pain induced by complete Freund's adjuvant.
Intellectual Disability
Fragile X mental retardation protein: nucleocytoplasmic shuttling and association with somatodendritic ribosomes.
Intellectual Disability
Fragile X mental retardation: misregulation of protein synthesis in the developing brain?
Intellectual Disability
Fragile X protein controls neural stem cell proliferation in the Drosophila brain.
Intellectual Disability
Fragile X protein FMRP is required for homeostatic plasticity and regulation of synaptic strength by retinoic acid.
Intellectual Disability
Fragile X related protein 1 clusters with ribosomes and messenger RNAs at a subset of dendritic spines in the mouse hippocampus.
Intellectual Disability
Fragile X Syndrome: From molecular pathology to therapy.
Intellectual Disability
FRAXE-associated mental retardation protein (FMR2) is an RNA-binding protein with high affinity for G-quartet RNA forming structure.
Intellectual Disability
FXR1 splicing is important for muscle development and biomolecular condensates in muscle cells.
Intellectual Disability
GABAB receptor upregulates fragile X mental retardation protein expression in neurons.
Intellectual Disability
Handling FMRP and its molecular partners: Structural insights into Fragile X Syndrome.
Intellectual Disability
Heads-up: New roles for the fragile X mental retardation protein in neural stem and progenitor cells.
Intellectual Disability
HITS-CLIP in various brain areas reveals new targets and new modalities of RNA binding by fragile X mental retardation protein.
Intellectual Disability
Identification of consensus binding sites clarifies FMRP binding determinants.
Intellectual Disability
Identification of FMRP target mRNAs in the developmental brain: FMRP might coordinate Ras/MAPK, Wnt/?-catenin, and mTOR signaling during corticogenesis.
Intellectual Disability
Identification of fragile X syndrome specific molecular markers in human fibroblasts: a useful model to test the efficacy of therapeutic drugs.
Intellectual Disability
Identification of mouse YB1/p50 as a component of the FMRP-associated mRNP particle.
Intellectual Disability
Identity of the RNA-binding protein K of hnRNP particles with protein H16, a sequence-specific single strand DNA-binding protein.
Intellectual Disability
Imbalance of synaptic actin dynamics as a key to fragile X syndrome?
Intellectual Disability
Increased Cardiac Arrhythmogenesis Associated With Gap Junction Remodeling With Upregulation of RNA-Binding Protein FXR1.
Intellectual Disability
Interactions of the G quartet forming semaphorin 3F RNA with the RGG box domain of the fragile X protein family.
Intellectual Disability
Involvement of FMRP in Primary MicroRNA Processing via Enhancing Drosha Translation.
Intellectual Disability
Involvement of Phosphodiesterase 2A Activity in the Pathophysiology of Fragile X Syndrome.
Intellectual Disability
Kinase pathway inhibition restores PSD95 induction in neurons lacking fragile X mental retardation protein.
Intellectual Disability
Kissing complex RNAs mediate interaction between the Fragile-X mental retardation protein KH2 domain and brain polyribosomes.
Intellectual Disability
Linking the Fragile X mental retardation protein to the lipoxygenase pathway.
Intellectual Disability
Lost once, the Fragile X Mental Retardation protein is now back onto brain polyribosomes.
Intellectual Disability
Low-normal FMR1 CGG repeat length: phenotypic associations.
Intellectual Disability
Metabotropic glutamate receptors and fragile x mental retardation protein: partners in translational regulation at the synapse.
Intellectual Disability
Metabotropic receptor-dependent long-term depression persists in the absence of protein synthesis in the mouse model of fragile X syndrome.
Intellectual Disability
Methylation regulates the intracellular protein-protein and protein-RNA interactions of FMRP.
Intellectual Disability
Modeling Fragile X Syndrome in Drosophila.
Intellectual Disability
Modelling fragile X syndrome in the laboratory setting: A behavioral perspective.
Intellectual Disability
Modulation of dendritic spines and synaptic function by Rac1: a possible link to Fragile X syndrome pathology.
Intellectual Disability
Molecular and Cellular Aspects of Mental Retardation in the Fragile X Syndrome: From Gene Mutation/s to Spine Dysmorphogenesis.
Intellectual Disability
mRNA and protein expression for novel GABAA receptors ? and ?2 are altered in schizophrenia and mood disorders; relevance to FMRP-mGluR5 signaling pathway.
Intellectual Disability
Multiple autism-linked genes mediate synapse elimination via proteasomal degradation of a synaptic scaffold PSD-95.
Intellectual Disability
Multiple Gq-coupled receptors converge on a common protein synthesis-dependent long-term depression that is affected in fragile X syndrome mental retardation.
Intellectual Disability
Muscle-Specific FXR1 Isoforms in Squamous Cell Cancer.
Intellectual Disability
Neuronal activity drives FMRP- and HSPG-dependent matrix metalloproteinase function required for rapid synaptogenesis.
Intellectual Disability
New Insights Into the Role of Cav2 Protein Family in Calcium Flux Deregulation in Fmr1-KO Neurons.
Intellectual Disability
On BC1 RNA and the fragile X mental retardation protein.
Intellectual Disability
Overexpression of Down syndrome cell adhesion molecule impairs precise synaptic targeting.
Intellectual Disability
Phosphorylation of FMRP inhibits association with Dicer.
Intellectual Disability
Post-translational modifications of the Fragile X Mental Retardation Protein in neuronal function and dysfunction.
Intellectual Disability
Postsynaptic FMRP bidirectionally regulates excitatory synapses as a function of developmental age and MEF2 activity.
Intellectual Disability
Proteomic analyses of nucleus laminaris identified candidate targets of the fragile X mental retardation protein.
Intellectual Disability
Proteomic analysis reveals CCT is a target of Fragile X mental retardation protein regulation in Drosophila.
Intellectual Disability
Quantitative phosphoproteomics of murine Fmr1-KO cell lines provides new insights into FMRP-dependent signal transduction mechanisms.
Intellectual Disability
Quantitative profiling of brain lipid raft proteome in a mouse model of fragile X syndrome.
Intellectual Disability
Reduced mitochondrial fusion and Huntingtin levels contribute to impaired dendritic maturation and behavioral deficits in Fmr1-mutant mice.
Intellectual Disability
Regulation of molecular pathways in the Fragile X Syndrome: insights into Autism Spectrum Disorders.
Intellectual Disability
Regulation of neuronal excitability by interaction of fragile X mental retardation protein with slack potassium channels.
Intellectual Disability
Reward-Related Expectations Trigger Dendritic Spine Plasticity in the Mouse Ventrolateral Orbitofrontal Cortex.
Intellectual Disability
RNA and microRNAs in fragile X mental retardation.
Intellectual Disability
Role of FMRP in rapid antidepressant effects and synapse regulation.
Intellectual Disability
Roles of fragile X mental retardation protein in dopaminergic stimulation-induced synapse-associated protein synthesis and subsequent alpha-amino-3-hydroxyl-5-methyl-4-isoxazole-4-propionate (AMPA) receptor internalization.
Intellectual Disability
S6K1 phosphorylates and regulates fragile X mental retardation protein (FMRP) with the neuronal protein synthesis-dependent mammalian target of rapamycin (mTOR) signaling cascade.
Intellectual Disability
Semaphorin-3A Promotes Degradation of Fragile X Mental Retardation Protein in Growth Cones via the Ubiquitin-Proteasome Pathway.
Intellectual Disability
SnapShot: FMRP mRNA targets and diseases.
Intellectual Disability
Species-dependent posttranscriptional regulation of NOS1 by FMRP in the developing cerebral cortex.
Intellectual Disability
Structural and Functional Abnormalities in the Olfactory System of Fragile X Syndrome Models.
Intellectual Disability
Targeting NUFIP1 Suppresses Growth and Induces Senescence of Colorectal Cancer Cells.
Intellectual Disability
Targeting the endocannabinoid system in the treatment of fragile X syndrome.
Intellectual Disability
Temporal-specific roles of fragile X mental retardation protein in the development of the hindbrain auditory circuit.
Intellectual Disability
The chicken FMR1 gene is highly conserved with a CCT 5'-untranslated repeat and encodes an RNA-binding protein.
Intellectual Disability
The FMRP regulon: from targets to disease convergence.
Intellectual Disability
The FMRP/GRK4 mRNA interaction uncovers a new mode of binding of the Fragile X mental retardation protein in cerebellum.
Intellectual Disability
The fragile X mental retardation protein FMRP binds elongation factor 1A mRNA and negatively regulates its translation in vivo.
Intellectual Disability
The fragile X mental retardation protein is a molecular adaptor between the neurospecific KIF3C kinesin and dendritic RNA granules.
Intellectual Disability
The fragile X mental retardation protein promotes adjustments in cocaine self-administration that preserve reinforcement level.
Intellectual Disability
The Fragile X Mental Retardation Protein Regulates Striatal Medium Spiny Neuron Synapse Density and Dendritic Spine Morphology.
Intellectual Disability
The fragile X mental retardation protein, FMRP, recognizes G-quartets.
Intellectual Disability
The fragile X protein controls microtubule-associated protein 1B translation and microtubule stability in brain neuron development.
Intellectual Disability
The G-quartet containing FMRP binding site in FMR1 mRNA is a potent exonic splicing enhancer.
Intellectual Disability
The gene encoding the fragile X RNA-binding protein is controlled by nuclear respiratory factor 2 and the CREB family of transcription factors.
Intellectual Disability
The Human Fragile X Mental Retardation Protein Inhibits the Elongation Step of Translation through Its RGG and C-Terminal Domains.
Intellectual Disability
The nuclear MicroSpherule protein 58 is a novel RNA-binding protein that interacts with fragile X mental retardation protein in polyribosomal mRNPs from neurons.
Intellectual Disability
The RNA-binding protein FMRP facilitates the nuclear export of N6-methyladenosine-containing mRNAs.
Intellectual Disability
The RNA-binding protein Nab2 regulates the proteome of the developing Drosophila brain.
Intellectual Disability
The RNA-binding protein, ZC3H14, is required for proper poly(A) tail length control, expression of synaptic proteins, and brain function in mice.
Intellectual Disability
The RNA-binding proteins FMR1, rasputin and caprin act together with the UBA protein lingerer to restrict tissue growth in Drosophila melanogaster.
Intellectual Disability
The Search for an Effective Therapy to Treat Fragile X Syndrome: Dream or Reality?
Intellectual Disability
The translational regulator FMRP controls lipid and glucose metabolism in mice and humans.
Intellectual Disability
Toward fulfilling the promise of molecular medicine in fragile X syndrome.
Intellectual Disability
Trapping of messenger RNA by Fragile X Mental Retardation protein into cytoplasmic granules induces translation repression.
Intellectual Disability
Understanding fragile X syndrome: insights from animal models.
Intellectual Disability
Widespread Alterations in Translation Elongation in the Brain of Juvenile Fmr1 Knockout Mice.
Intervertebral Disc Degeneration
RNA-Binding Protein HuR Suppresses Inflammation and Promotes Extracellular Matrix Homeostasis via NKRF in Intervertebral Disc Degeneration.
Intervertebral Disc Degeneration
RNA-binding protein HuR suppresses senescence through Atg7 mediated autophagy activation in diabetic intervertebral disc degeneration.
Iron Deficiencies
Differences in the regulation of iron regulatory protein-1 (IRP-1) by extra- and intracellular oxidative stress.
Iron Deficiencies
Post-transcriptional regulation of iron homeostasis in Saccharomyces cerevisiae.
Ischemic Stroke
Characterization of the transient middle cerebral artery occlusion model of ischemic stroke in a HuR transgenic mouse line.
Ischemic Stroke
Extracellular CIRP Activates the IL-6R?/STAT3/Cdk5 Pathway in Neurons.
Ischemic Stroke
Monocyte function and plasma levels of interleukin-8 in acute ischemic stroke.
Ischemic Stroke
RNPS1 inhibition aggravates ischemic brain injury and promotes neuronal death.
Ischemic Stroke
Transgenic expression of HuR increases vasogenic edema and impedes functional recovery in rodent ischemic stroke.
Joint Diseases
Integrated Diagnosis Project for Inflammatory Myopathies: An association between autoantibodies and muscle pathology.
Joint Diseases
Prevalence of antibodies to human parvovirus B19 nonstructural protein in persons with various clinical outcomes following B19 infection.
Joint Diseases
Skeletal Muscle Involvement in Antisynthetase Syndrome.
Joint Diseases
[Antisynthetase myopathy].
Keloid
Heat Shock Protein 90 Inhibitor Decreases Collagen Synthesis of Keloid Fibroblasts and Attenuates the Extracellular Matrix on the Keloid Spheroid Model.
Keratitis
16S Ribosomal RNA PCR Versus Conventional Diagnostic Culture in the Investigation of Suspected Bacterial Keratitis.
Keratosis, Actinic
Expression of Cold-Inducible RNA-Binding Protein in Normal Skin, Actinic Keratosis and Squamous Cell Carcinoma.
Kernicterus
Bilirubin encephalopathy: effect on RNA polymerase activity and chromatin template activity in the brain of the Gunn rat.
Kidney Diseases
Inhibition of RNA-binding protein HuR reduces glomerulosclerosis in experimental nephritis.
Kidney Diseases
WT1 and kidney progenitor cells.
Kidney Diseases, Cystic
Crystal Structure of Bicc1 SAM Polymer and Mapping of Interactions between the Ciliopathy-Associated Proteins Bicc1, ANKS3, and ANKS6.
Kidney Diseases, Cystic
Role of the RNA-binding protein Bicaudal-C1 and interacting factors in cystic kidney diseases.
Kidney Neoplasms
The expression of RNA-binding protein RBM38 decreased in renal cell carcinoma and represses renal cancer cell proliferation, migration, and invasion.
Langerhans Cell Sarcoma
The Expression of Insulin-Like Growth Factor 2 Messenger RNA-Binding Protein 3 in Langerhans Cell Histiocytosis and Langerhans Cell Sarcoma.
Lassa Fever
The Lassa fever virus L gene: nucleotide sequence, comparison, and precipitation of a predicted 250 kDa protein with monospecific antiserum.
Legionnaires' Disease
The alternative sigma factor sigma28 of Legionella pneumophila restores flagellation and motility to an Escherichia coli fliA mutant.
Leprosy
Computational saturation mutagenesis to predict structural consequences of systematic mutations in the beta subunit of RNA polymerase in Mycobacterium leprae.
Leprosy, Lepromatous
Molecular basis of rifampin resistance in Mycobacterium leprae.
Leukemia
A lentiviral functional proteomics approach identifies chromatin remodeling complexes important for the induction of pluripotency.
Leukemia
BLM helicase facilitates RNA polymerase I-mediated ribosomal RNA transcription.
Leukemia
Capture of antigen-specific T lymphocytes from human blood by selective immortalization to establish long-term T-cell lines maintaining primary cell characteristics.
Leukemia
Cooperative translational control of polymorphic BAFF by NF90 and miR-15a.
Leukemia
Deoxyribonucleic acid-dependent ribonucleic acid polymerases from spleen of uninfected and Rauscher murine leukemia virus-infected NIH Swiss mice.?
Leukemia
Differential inhibition of various deoxyribonucleic acid polymerases by Evans blue and aurintricarboxylic acid.
Leukemia
Differential inhibition of various deoxyribonucleic and ribonucleic acid polymerases by suramin.
Leukemia
Effect of antineoplastic and cytotoxic Mannich Bases derived from conjugated styryl ketones on mitochondrial respiration in rat liver cells.
Leukemia
Effect of Rauscher leukemia virus-specific proteins on reverse transcriptase. Binding between reverse transcriptase and p30.
Leukemia
Effects of streptovaricins and their degradation products on RNA-directed DNA polymerase of Rauscher leukemia virus.
Leukemia
EWS represses cofilin 1 expression by inducing nuclear retention of cofilin 1 mRNA.
Leukemia
Expression of EVI1 in myelodysplastic syndromes and other hematologic malignancies without 3q26 translocations.
Leukemia
Fusion protein EWS-FLI1 is incorporated into a protein granule in cells.
Leukemia
Immunohistochemical evaluation of reverse transcriptase in breast carcinoma with polyclonal antibodies raised in rabbit.
Leukemia
Inhibition of reverse transcriptase and Taq DNA polymerase by compounds possessing the coumarin framework.
Leukemia
Interaction of N-trifluoroacetyladriamycin-14-O-hemiadipate with chicken leukemia RNA polymerase. Formation of drug-enzyme complex.
Leukemia
Intrinsic properties of reverse transcriptase in reverse transcription. Associated RNase H is essentially regarded as an endonuclease.
Leukemia
Long noncoding RNA PART1 restrains aggressive gastric cancer through the epigenetic silencing of PDGFB via the PLZF-mediated recruitment of EZH2.
Leukemia
Male sterility and enhanced radiation sensitivity in TLS(-/-) mice.
Leukemia
Musashi2 sustains the mixed-lineage leukemia-driven stem cell regulatory program.
Leukemia
Nucleolin and the packaging signal, psi, promote the budding of human immunodeficiency virus type-1 (HIV-1).
Leukemia
Promyelocytic leukemia isoform IV confers resistance to encephalomyocarditis virus via the sequestration of 3D polymerase in nuclear bodies.
Leukemia
Regulation of c-jun expression during induction of monocytic differentiation by okadaic acid.
Leukemia
Retargeting Polyomavirus-Like Particles to Cancer Cells by Chemical Modification of Capsid Surface.
Leukemia
Reverse transcriptase. The use of cloned Moloney murine leukemia virus reverse transcriptase to synthesize DNA from RNA.
Leukemia
RNA polymerase activity following infection with murine leukemia virus.
Leukemia
RNA-binding protein IGF2BP1 maintains leukemia stem cell properties by regulating HOXB4, MYB, and ALDH1A1.
Leukemia
RNA-dependent DNA polymerase activity in ocular granulocytic sarcoma associated to acute myelomonocytic leukemia in Turkish children. Biochemical and immunological characterization of the enzyme.
Leukemia
Role of cellular RNA polymerases in virus-induced leukemogenesis.
Leukemia
Selective immortalization of tumor-specific T cells to establish long-term T-cell lines maintaining primary cell characteristics.
Leukemia
Targeted knockdown of the RNA-binding protein CRD-BP promotes cell proliferation via an insulin-like growth factor II-dependent pathway in human K562 leukemia cells.
Leukemia
The RNA-binding protein IGF2BP3 is critical for MLL-AF4-mediated leukemogenesis.
Leukemia
The RNA-binding protein IMP-3 is a translational activator of insulin-like growth factor II leader-3 mRNA during proliferation of human K562 leukemia cells.
Leukemia, Erythroblastic, Acute
Accurate initiation of human epsilon-globin RNA synthesis by Escherichia coli RNA polymerase in isolated nuclei of K562 erythroleukemia cells.
Leukemia, Erythroblastic, Acute
Cytoplasmic synthesis of globin RNA in differentiated murine erythroleukemia cells: possible involvement of RNA-dependent RNA polymerase.
Leukemia, Erythroblastic, Acute
Study of the role of retinoblastoma protein in terminal differentiation of murine erythroleukemia cells.
Leukemia, Lymphocytic, Chronic, B-Cell
Tryptophanyl transfer RNA synthetase from lymphocytes of human chronic lymphocytic leukemia.
Leukemia, Lymphoid
Antitumor agents. XXXIV: Mechanism of action of bruceoside A and brusatol on nucleic acid metabolism of P-388 lymphocytic leukemia cells.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
A novel gene, MSI2, encoding a putative RNA-binding protein is recurrently rearranged at disease progression of chronic myeloid leukemia and forms a fusion gene with HOXA9 as a result of the cryptic t(7;17)(p15;q23).
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Detection of the BCR/ABL fusion gene in chronic myeloid leukemia by RNA polymerase chain reaction.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
High levels of the BCR/ABL oncoprotein are required for the MAPK-hnRNP-E2 dependent suppression of C/EBPalpha-driven myeloid differentiation.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
[Detection of tumor load in chronic myeloid leukemia during treatment with transplantation by conventional cytogenetics, nested-RT-PCR and FISH]
Leukemia, Myeloid
An in vivo genome-wide CRISPR screen identifies the RNA-binding protein Staufen2 as a key regulator of myeloid leukemia.
Leukemia, Myeloid
An RNA-binding protein gene, TLS/FUS, is fused to ERG in human myeloid leukemia with t(16;21) chromosomal translocation.
Leukemia, Myeloid
Musashi 2 contributes to the stemness and chemoresistance of liver cancer stem cells via LIN28A activation.
Leukemia, Myeloid, Acute
MicroRNA-519 enhances HL60 human acute myeloid leukemia cell line proliferation by reducing the expression level of RNA-binding protein human antigen R.
Leukemia, Myeloid, Acute
Musashi-2 Silencing Exerts Potent Activity against Acute Myeloid Leukemia and Enhances Chemosensitivity to Daunorubicin.
Leukemia, Myeloid, Acute
Targeting an RNA-Binding Protein Network in Acute Myeloid Leukemia.
Leukemia, T-Cell
Capture of antigen-specific T lymphocytes from human blood by selective immortalization to establish long-term T-cell lines maintaining primary cell characteristics.
Leukemia, T-Cell
Transcriptional activation of RNA polymerase III-dependent genes by the human T-cell leukemia virus type 1 tax protein.
Leukoencephalopathies
Immunoenzymatic labelling of JC papovavirus T antigen in brains of patients with progressive multifocal leukoencephalopathy.
Leukoencephalopathy, Progressive Multifocal
Immunoenzymatic labelling of JC papovavirus T antigen in brains of patients with progressive multifocal leukoencephalopathy.
Leukoplakia
Heterogeneous ribonucleoprotein K is a marker of oral leukoplakia and correlates with poor prognosis of squamous cell carcinoma.
Leukoplakia, Oral
Heterogeneous ribonucleoprotein K is a marker of oral leukoplakia and correlates with poor prognosis of squamous cell carcinoma.
Lichen Planus
A retrospective case-control study of hepatitis C virus infection and oral lichen planus in Japan: association study with mutations in the core and NS5A region of hepatitis C virus.
Lichen Planus, Oral
A retrospective case-control study of hepatitis C virus infection and oral lichen planus in Japan: association study with mutations in the core and NS5A region of hepatitis C virus.
Lipodystrophy
Cutaneous toxicities of antiretroviral therapy for HIV: part I. Lipodystrophy syndrome, nucleoside reverse transcriptase inhibitors, and protease inhibitors.
Liposarcoma
A protein-protein interaction of stress-responsive myosin VI endowed to inhibit neural progenitor self-replication with RNA binding protein, TLS, in murine hippocampus.
Liposarcoma
Arginine methylation of translocated in liposarcoma (TLS) inhibits its binding to long noncoding RNA, abrogating TLS-mediated repression of CBP/p300 activity.
Liposarcoma
Characterization of a Family of RanBP2-Type Zinc Fingers that Can Recognize Single-Stranded RNA.
Liposarcoma
Elevated FUS/TLS expression is negatively associated with E-cadherin expression and prognosis of patients with non-small cell lung cancer.
Liposarcoma
FUS/TLS as a polyglutamine aggregate interacting protein.
Liposarcoma
Male sterility and enhanced radiation sensitivity in TLS(-/-) mice.
Liposarcoma
NEAT1 is Required for Survival of Breast Cancer Cells Through FUS and miR-548.
Liposarcoma
RNA-binding protein TLS is a major nuclear aggregate-interacting protein in huntingtin exon 1 with expanded polyglutamine-expressing cells.
Liposarcoma
The RNA-binding Protein Fused in Sarcoma (FUS) Functions Downstream of Poly(ADP-ribose) Polymerase (PARP) in Response to DNA Damage.
Liposarcoma, Myxoid
A renal cell carcinoma with EWSR1-TFE3 fusion gene.
Liposarcoma, Myxoid
An RNA-binding protein gene, TLS/FUS, is fused to ERG in human myeloid leukemia with t(16;21) chromosomal translocation.
Liposarcoma, Myxoid
CHOP/GADD153 and methionyl-tRNA synthetase (MetRS) genes overlap in a conserved region that controls mRNA stability.
Liposarcoma, Myxoid
Fusion of CHOP to a novel RNA-binding protein in human myxoid liposarcoma.
Liposarcoma, Myxoid
Induction of a secreted protein by the myxoid liposarcoma oncogene.
Liver Cirrhosis
Aberrant expression of fetal RNA-binding protein p62 in liver cancer and liver cirrhosis.
Liver Cirrhosis
Activation of ferritinophagy is required for the RNA-binding protein ELAVL1/HuR to regulate ferroptosis in hepatic stellate cells.
Liver Cirrhosis
Effect of mutation in the hepatitis C virus nonstructural 5B region on HCV replication.
Liver Cirrhosis
Genotype 3-hepatitis C virus' last line of defense.
Liver Cirrhosis
linc-SCRG1 accelerates liver fibrosis by decreasing RNA-binding protein tristetraprolin.
Liver Cirrhosis
RNA-binding protein RBMS3 is expressed in activated hepatic stellate cells and liver fibrosis and increases expression of transcription factor Prx1.
Liver Cirrhosis
TAF and TDF attenuate liver fibrosis through NS5ATP9, TGF?1/Smad3, and NF-?B/NLRP3 inflammasome signaling pathways.
Liver Cirrhosis
THE EFFECT OF STEM CELLS AS AN ADJUVANT ON THE IMMUNOGENICITY OF A POTENTIAL ANTI-SCHISTOSOMAL VACCINE IN MICE.
Liver Cirrhosis, Alcoholic
Identification of beta-subunit of bacterial RNA-polymerase--a non-species-specific bacterial protein--as target of antibodies in primary biliary cirrhosis.
Liver Cirrhosis, Biliary
Identification of beta-subunit of bacterial RNA-polymerase--a non-species-specific bacterial protein--as target of antibodies in primary biliary cirrhosis.
Liver Cirrhosis, Biliary
[Autoantibodies of Inflammatory Myopathies: Update].
Liver Diseases
Assessment of hepatitis C virus RNA levels by quantitative competitive RNA polymerase chain reaction: high-titer viremia correlates with advanced stage of disease.
Liver Diseases
Clinical evaluation of three anti-HCV ELISAs in patients with various liver diseases.
Liver Diseases
Genetic and biochemical diversity in the HCV NS5B RNA polymerase in the context of interferon alpha plus ribavirin therapy.
Liver Diseases
HCV Genotype 6a Escape from and Resistance to Velpatasvir, Pibrentasvir, and Sofosbuvir in Robust Infectious Cell Culture Models.
Liver Diseases
In situ enzymatic oligonucleotide amplification of hepatitis C virus-RNA in liver biopsy specimens (reverse transcriptase in situ polymerase chain reaction) after orthotopic liver transplantation for hepatitis C-related liver disease.
Liver Diseases
Outcome of All-Oral Direct-Acting Antiviral Regimens on the Rate of Development of Hepatocellular Carcinoma in Patients with Hepatitis C Virus Genotype 1-Related Chronic Liver Disease.
Liver Diseases
SIRT1 mediates the role of RNA-binding protein QKI 5 in the synthesis of triglycerides in non-alcoholic fatty liver disease mice via the PPAR?/FoxO1 signaling pathway.
Liver Failure, Acute
Detection of hepatitis C virus with RNA polymerase chain reaction in fulminant hepatic failure.
Liver Failure, Acute
Urgent liver transplantation for nevirapine-induced acute liver failure: report of a case and review of the literature.
Liver Neoplasms
Aberrant expression of fetal RNA-binding protein p62 in liver cancer and liver cirrhosis.
Liver Neoplasms
Cold-inducible RNA-binding protein promotes the development of liver cancer.
Liver Neoplasms
Hepatitis C virus nonstructural 5A protein inhibits the starvation?induced apoptosis of hepatoblastoma cells by increasing Beclin 1 expression.
Liver Neoplasms
Identification of an immune-related RNA-binding protein signature to predict survival and targeted therapy responses in liver cancer.
Liver Neoplasms
RBMY, a male germ cell-specific RNA-binding protein, activated in human liver cancers and transforms rodent fibroblasts.
Liver Neoplasms
Zmat3 Is a Key Splicing Regulator in the p53 Tumor Suppression Program.
Liver Neoplasms, Experimental
Isolation and characterization of nonhistone chromosomal protein C-14 which stimulates RNA synthesis.
Liver Neoplasms, Experimental
Nucleolar and extranucleolar chromatin of rat Novikoff hepatoma cells. Separation and partial characterization of RNA polymerase activities.
Lung Diseases, Interstitial
A case of macrophage activation syndrome in a patient with anti-synthetase syndrome.
Lung Diseases, Interstitial
Anti-synthetase syndrome: a new autoantibody to phenylalanyl transfer RNA synthetase (anti-Zo) associated with polymyositis and interstitial pneumonia.
Lung Diseases, Interstitial
Antisynthetase Syndrome with Anti-Jo1 Antibodies in 48 Patients: Pulmonary Involvement Predicts Disease-modifying Antirheumatic Drug Use.
Lung Diseases, Interstitial
Association of anti-aminoacyl-transfer RNA synthetase antibody and anti-melanoma differentiation-associated gene 5 antibody with the therapeutic response of polymyositis/dermatomyositis-associated interstitial lung disease.
Lung Diseases, Interstitial
Clinical features of anti-synthetase syndrome associated interstitial lung disease: a retrospective cohort in China.
Lung Diseases, Interstitial
Clinical manifestations and outcome of anti-aminoacyl-transfer RNA synthetase antibody and anti-melanoma differentiation-associated gene 5 antibody positive patients with interstitial lung disease.
Lung Diseases, Interstitial
Clinicopathological analysis of mechanic's hand associated with dermatomyositis.
Lung Diseases, Interstitial
Integrated Diagnosis Project for Inflammatory Myopathies: An association between autoantibodies and muscle pathology.
Lung Diseases, Interstitial
Mechanic's hand; is it a prodromic sign of disease relapse of anti-synthetase syndrome; a case report.
Lung Diseases, Interstitial
Skeletal Muscle Involvement in Antisynthetase Syndrome.
Lung Diseases, Interstitial
The Diagnosis and Treatment of Antisynthetase Syndrome.
Lung Diseases, Interstitial
The pulmonary histopathologic manifestations of the anti-PL7/antithreonyl transfer RNA synthetase syndrome.
Lung Diseases, Interstitial
The pulmonary histopathology of anti-KS transfer RNA synthetase syndrome.
Lung Diseases, Interstitial
Treatment of antisynthetase-associated interstitial lung disease with tacrolimus.
Lung Diseases, Interstitial
[Antisynthetase myopathy].
Lung Diseases, Interstitial
[Antisynthetase syndrome: a retrospective study of 14 patients].
Lung Injury
Attenuation of hemorrhage-associated lung injury by adjuvant treatment with C23, an oligopeptide derived from cold-inducible RNA-binding protein (CIRP).
Lung Injury
Attenuation of hemorrhage-associated lung injury by adjuvant treatment with C23, an oligopeptide derived from cold-inducible RNA-binding protein.
Lung Injury
C23, an oligopeptide derived from cold-inducible RNA-binding protein, suppresses inflammation and reduces lung injury in neonatal sepsis.
Lung Injury
Cold-inducible RNA-binding protein (CIRP) causes sepsis-associated acute lung injury via induction of endoplasmic reticulum stress.
Lung Injury
Luteolin Suppresses Sepsis-Induced Cold-Inducible Rna-Binding Protein Production and Lung Injury in Neonatal MICE.
Lung Injury
Mir-331-3p Inhibits PRRSV-2 Replication and Lung Injury by Targeting PRRSV-2 ORF1b and Porcine TNF-?.
Lung Neoplasms
Alpha CP-4, encoded by a putative tumor suppressor gene at 3p21, but not its alternative splice variant alpha CP-4a, is underexpressed in lung cancer.
Lung Neoplasms
Application of Serum ELAVL4 (HuD) Antigen Assay for Small Cell Lung Cancer Diagnosis.
Lung Neoplasms
Elevated FUS/TLS expression is negatively associated with E-cadherin expression and prognosis of patients with non-small cell lung cancer.
Lung Neoplasms
Expression of TARBP1 protein in human non-small-cell lung cancer and its prognostic significance.
Lung Neoplasms
Expression profile, clinical significance, and biological function of insulin-like growth factor 2 messenger RNA-binding proteins in non-small cell lung cancer.
Lung Neoplasms
Heterogeneous nuclear ribonucleoprotein B1 expression in malignant mesothelioma.
Lung Neoplasms
HnRNP-L promotes prostate cancer progression by enhancing cell cycling and inhibiting apoptosis.
Lung Neoplasms
Increased expression of insulin-like growth factor-II messenger RNA-binding protein 1 is associated with tumor progression in patients with lung cancer.
Lung Neoplasms
KH-type splicing regulatory protein (KHSRP) contributes to tumorigenesis by promoting miR-26a maturation in small cell lung cancer.
Lung Neoplasms
L523S, an RNA-binding protein as a potential therapeutic target for lung cancer.
Lung Neoplasms
MUC1-C Induces the LIN28B?LET-7?HMGA2 Axis to Regulate Self-Renewal in NSCLC.
Lung Neoplasms
Musashi-2 (MSI2) regulates epidermal growth factor receptor (EGFR) expression and response to EGFR inhibitors in EGFR-mutated non-small cell lung cancer (NSCLC).
Lung Neoplasms
QKI-5 regulates the alternative splicing of cytoskeletal gene ADD3 in lung cancer.
Lung Neoplasms
Quaking orchestrates a post-transcriptional regulatory network of endothelial cell cycle progression critical to angiogenesis and metastasis.
Lung Neoplasms
Replicase-based plasmid DNA shows anti-tumor activity.
Lung Neoplasms
RNA-binding motif protein 10 induces apoptosis and suppresses proliferation by activating p53.
Lung Neoplasms
RNA-binding protein KHSRP promotes tumor growth and metastasis in non-small cell lung cancer.
Lung Neoplasms
RNA-binding Protein Trinucleotide repeat-containing 6A Regulates the Formation of Circular RNA 0006916, with Important Functions in Lung Cancer Cells.
Lung Neoplasms
RNA-binding Protein, GADD45-alpha, p27(Kip1), p53 and Genotoxic Stress Response in Relation to Chemoresistance in Cancer.
Lung Neoplasms
Role of RNA-binding protein 5 in the diagnosis and chemotherapeutic response of lung cancer.
Lung Neoplasms
The Expression of RNA-Binding Protein HuR in Non-Small Cell Lung Cancer Correlates with Vascular Endothelial Growth Factor-C Expression and Lymph Node Metastasis.
Lung Neoplasms
The oncogenic RNA-binding protein SRSF1 regulates LIG1 in non-small cell lung cancer.
Lung Neoplasms
The RNA-binding protein HuR stabilizes the cytosolic phospholipase A2{alpha} mRNA under interleukin-1{beta} treatment in non-small cell lung cancer A549 cells.
Lung Neoplasms
The RNA-Binding Protein QKI Suppresses Cancer-Associated Aberrant Splicing.
Lung Neoplasms
The RNA-binding protein Sam68 is critical for non-small cell lung cancer cell proliferation by regulating Wnt/?-catenin pathway.
Lung Neoplasms
The RNA-binding protein SART3 promotes miR-34a biogenesis and G1 cell cycle arrest in lung cancer cells.
Lung Neoplasms
Tumor-specific activation of human telomerase reverses transcriptase promoter activity by activating enhancer-binding protein-2beta in human lung cancer cells.
Lupus Erythematosus, Cutaneous
The Ro 60 kDa autoantigen comes into focus: interpreting epitope mapping experiments on the basis of structure.
Lupus Erythematosus, Systemic
A lupus-like syndrome develops in mice lacking the Ro 60-kDa protein, a major lupus autoantigen.
Lupus Erythematosus, Systemic
Developmental characterization of a Drosophila RNA-binding protein homologous to the human systemic lupus erythematosus-associated La/SS-B autoantigen.
Lupus Erythematosus, Systemic
Identification of beta-subunit of bacterial RNA-polymerase--a non-species-specific bacterial protein--as target of antibodies in primary biliary cirrhosis.
Lupus Erythematosus, Systemic
Phage-displayed La/SS-B antigen as a diagnostic reagent.
Lupus Erythematosus, Systemic
Scleroderma-specific autoantibodies embedded in immune complexes mediate endothelial damage: an early event in the pathogenesis of systemic sclerosis.
Lupus Erythematosus, Systemic
Sensitivity and specificity of anti-Jo-1 antibodies in autoimmune diseases with myositis.
Lupus Erythematosus, Systemic
The RNA binding protein La/SS-B promotes RIG-I-mediated type I and type III IFN responses following Sendai viral infection.
Lupus Erythematosus, Systemic
The Ro 60 kDa autoantigen comes into focus: interpreting epitope mapping experiments on the basis of structure.
Lupus Erythematosus, Systemic
The Ro 60 kDa autoantigen: insights into cellular function and role in autoimmunity.
Lupus Erythematosus, Systemic
The Root Extract of Gentiana macrophylla Pall. Alleviates B19-NS1-Exacerbated Liver Injuries in NZB/W F1 Mice.
Lupus Nephritis
Anti-RNA polymerase I antibodies: potential role in the induction and progression of murine lupus nephritis.
Lyme Disease
Borrelia burgdorferi SpoVG DNA- and RNA-Binding Protein Modulates the Physiology of the Lyme Disease Spirochete.
Lyme Disease
Transcript decay mediated by RNase III in Borrelia burgdorferi.
Lymphatic Metastasis
Diffuse expression of RNA-binding protein IMP3 predicts high-stage lymph node metastasis and poor prognosis in colorectal adenocarcinoma.
Lymphatic Metastasis
Long non-coding RNA Loc490 inhibits gastric cancer cell proliferation and metastasis by upregulating RNA-binding protein Quaking.
Lymphatic Metastasis
The Expression of RNA-Binding Protein HuR in Non-Small Cell Lung Cancer Correlates with Vascular Endothelial Growth Factor-C Expression and Lymph Node Metastasis.
Lymphocytic Choriomeningitis
A Highly Conserved Leucine In Mammarenavirus Matrix Z Protein Is Required For Z Interaction With The Virus L Polymerase And Z Stability In Cells Harboring An Active Viral Ribonucleoprotein.
Lymphocytic Choriomeningitis
Antiviral protective immunity induced by major histocompatibility complex class I molecule-restricted viral T-lymphocyte epitopes inserted in various positions in immunologically self and nonself proteins.
Lymphocytic Choriomeningitis
Detection of virus-specific RNA-dependent RNA polymerase activity in extracts from cells infected with lymphocytic choriomeningitis virus: in vitro synthesis of full-length viral RNA species.
Lymphocytic Choriomeningitis
DNA-based immunisation against rabies and rabies-related viruses: towards multivalent vaccines.
Lymphocytic Choriomeningitis
The primary structure of the lymphocytic choriomeningitis virus L gene encodes a putative RNA polymerase.
Lymphoma
CREB targets define the gene expression signature of malignancies having reduced levels of the tumor suppressor tristetraprolin.
Lymphoma
Impaired ribosome biogenesis checkpoint activation induces p53-dependent MCL-1 degradation and MYC-driven lymphoma death.
Lymphoma
Increased IL-6 detection in adult and pediatric lymphoid tissue harboring Parvovirus B19.
Lymphoma
Nucleoproteins derived from subnuclear RNA polymerase complexes of metastatic large-cell lymphoma cells possess transcription activities and regulatory properties in vitro.
Lymphoma
Participation of poly(ADP-ribosyl)ation in the depression of RNA synthesis caused by treatment of mouse lymphoma cells with methylnitrosourea.
Lymphoma, B-Cell
Impaired ribosome biogenesis checkpoint activation induces p53-dependent MCL-1 degradation and MYC-driven lymphoma death.
Lymphoma, B-Cell
Long non-coding RNA DBH-AS1 promotes cancer progression in diffuse large B-cell lymphoma by targeting FN1 via RNA-binding protein BUD13.
Lymphoma, B-Cell
The Eµ-hnRNP K Murine Model of Lymphoma: Novel Insights into the Role of hnRNP K in B-Cell Malignancies.
Lymphoma, B-Cell
Uncovering the role of hnRNP K, an RNA-binding protein, in B-cell lymphomas.
Lymphoma, Large B-Cell, Diffuse
Long non-coding RNA DBH-AS1 promotes cancer progression in diffuse large B-cell lymphoma by targeting FN1 via RNA-binding protein BUD13.
Lymphoma, Non-Hodgkin
DNA-dependent RNA polymerases of Ehrlich carcinoma, other murine ascites tumors, and murine normal tissues.
Lymphoma, T-Cell
Interleukin-5 mRNA in three T-cell lymphomas with eosinophilia.
Lymphoproliferative Disorders
Hepatitis C virus upregulates B-cell receptor signaling: a novel mechanism for HCV-associated B-cell lymphoproliferative disorders.
Macular Degeneration
Autophagy Stimulus Promotes Early HuR Protein Activation and p62/SQSTM1 Protein Synthesis in ARPE-19 Cells by Triggering Erk1/2, p38
Malaria
A circular DNA in malaria parasites encodes an RNA polymerase like that of prokaryotes and chloroplasts.
Malaria
Identification of beta-subunit of bacterial RNA-polymerase--a non-species-specific bacterial protein--as target of antibodies in primary biliary cirrhosis.
Malaria
PfAlba1: master regulator of translation in the malaria parasite.
Malaria
RNA-binding protein-related sequence in a malaria antigen, clustered-asparagine-rich protein.
Malaria
The EU approved antimalarial pyronaridine shows antitubercular activity and synergy with rifampicin, targeting RNA polymerase.
Malaria
The malaria parasite Plasmodium falciparum encodes members of the Puf RNA-binding protein family with conserved RNA binding activity.
Malaria
The Puf-family RNA-binding protein PfPuf2 regulates sexual development and sex differentiation in the malaria parasite Plasmodium falciparum.
Malaria
The Puf-family RNA-binding protein Puf2 controls sporozoite conversion to liver stages in the malaria parasite.
Marek Disease
Improving the potency of DNA vaccine against Chicken Anemia Virus (CAV) by fusing VP1 protein of CAV to Marek's Disease Virus (MDV) Type-1 VP22 protein.
Massive Hepatic Necrosis
Analysis of hepatitis A virus protein 2B in sera of hepatitis A of various severities.
Massive Hepatic Necrosis
Genetic analysis of HAV strains in Tunisia reveals two new antigenic variants.
Mastitis
The clinical impact of antimicrobial resistance genomics in competition with she-camels recurrent mastitis metabolomics due to heterogeneous
Measles
A microcapillary column switching HPLC-electrospray ionization MS system for the direct identification of peptides presented by major histocompatibility complex class I molecules.
Measles
An amino-proximal domain of the L protein binds to the P protein in the measles virus RNA polymerase complex.
Measles
Cancer and Virus Leads by HTS, Chemical Design and SEA Data Mining.
Measles
Characterization of an RNA-dependent RNA polymerase activity associated with measles virus.
Measles
Characterization of in vitro transcription and transcriptional products of measles virus.
Measles
Hemagglutinin protein is a primary target of the measles virus-specific HLA-A2-restricted CD8+ T cell response during measles and after vaccination.
Measles
Host cell proteins required for measles virus reproduction.
Measles
Measles virus L protein evidences elements of ancestral RNA polymerase.
Measles
Measles Virus Nonstructural C Protein Modulates Viral RNA Polymerase Activity by Interacting with Host Protein SHCBP1.
Measles
Measles virus nucleocapsid protein can function in Sendai virus defective interfering particle genome synthesis in vitro.
Measles
Modulating the function of the measles virus RNA-dependent RNA polymerase by insertion of green fluorescent protein into the open reading frame.
Measles
Mutations in the measles virus C protein that up regulate viral RNA synthesis.
Measles
Non-nucleoside inhibitors of the measles virus RNA-dependent RNA polymerase complex activity: Synthesis and in vitro evaluation.
Measles
Non-nucleoside inhibitors of the measles virus RNA-dependent RNA polymerase: synthesis, structure-activity relationships, and pharmacokinetics.
Measles
Nonnucleoside inhibitor of measles virus RNA-dependent RNA polymerase complex activity.
Measles
Phosphorylation of measles virus phosphoprotein at S86 and/or S151 downregulates viral transcriptional activity.
Measles
Potent non-nucleoside inhibitors of the measles virus RNA-dependent RNA polymerase complex.
Measles
Sequence variability and function of measles virus 3' and 5' ends and intercistronic regions.
Measles
Showing your ID: intrinsic disorder as an ID for recognition, regulation and cell signaling.
Measles
Signature motifs of GDP polyribonucleotidyltransferase, a non-segmented negative strand RNA viral mRNA capping enzyme, domain in the L protein are required for covalent enzyme-pRNA intermediate formation.
Measles
Study of transcription in measles virus-infected Vero cells using cDNA probes prepared from poly(A)RNA from uninfected and infected cells.
Measles
Target analysis of the experimental measles therapeutic AS-136A.
Measles
The C Protein Is Recruited to Measles Virus Ribonucleocapsids by the Phosphoprotein.
Measles
The matrix protein of measles virus regulates viral RNA synthesis and assembly by interacting with the nucleocapsid protein.
Measles
The phosphoprotein (P) and L binding sites reside in the N-terminus of the L subunit of the measles virus RNA polymerase.
Measles
The structurally disordered paramyxovirus nucleocapsid protein tail domain is a regulator of the mRNA transcription gradient.
Measles
Therapeutic targeting of measles virus polymerase with ERDRP-0519 suppresses all RNA synthesis activity.
Measles
Vesicular Stomatitis Virus Phosphoprotein Dimerization Domain Is Dispensable for Virus Growth.
Medulloblastoma
Anti-apoptotic activity of Japanese encephalitis virus NS5 protein in human medulloblastoma cells treated with interferon-?.
Medulloblastoma
Inhibition of Long Noncoding RNA CRNDE Increases Chemosensitivity of Medulloblastoma Cells by Targeting miR-29c-3p.
Medulloblastoma
The RNA-Binding Protein Musashi1 Affects Medulloblastoma Growth via a Network of Cancer-Related Genes and Is an Indicator of Poor Prognosis.
Medulloblastoma
YBX1 Indirectly Targets Heterochromatin-Repressed Inflammatory Response-Related Apoptosis Genes through Regulating CBX5 mRNA.
Melanoma
A renal cell carcinoma with EWSR1-TFE3 fusion gene.
Melanoma
Crystal structure of the human heterogeneous ribonucleoprotein A18 RNA-recognition motif.
Melanoma
Dose-Dependent Inhibition of Melanoma Differentiation-Associated Gene 5-Mediated Activation of Type I Interferon Responses by Methyltransferase of Hepatitis E Virus.
Melanoma
Drug-induced expression of the RNA-binding protein HuR attenuates the adaptive response to BRAF inhibition in melanoma.
Melanoma
Dual mechanisms of action of the RNA-binding protein human antigen R explains its regulatory effect on melanoma cell migration.
Melanoma
Expression of the wt1 Wilms' tumor gene by normal and malignant human melanocytes.
Melanoma
Extracellular vesicle-dependent effect of RNA-binding protein IGF2BP1 on melanoma metastasis.
Melanoma
High RBM3 expression in prostate cancer independently predicts a reduced risk of biochemical recurrence and disease progression.
Melanoma
HUR protects NONO from degradation by mir320, which is induced by p53 upon UV irradiation.
Melanoma
Insulin-Like Growth Factor II mRNA-Binding Protein 3 Expression Correlates with Poor Prognosis in Acral Lentiginous Melanoma.
Melanoma
microRNA-340-mediated degradation of microphthalmia-associated transcription factor (MITF) mRNA is inhibited by coding region determinant binding protein (CRD-BP).
Melanoma
MicroRNA-340-mediated degradation of microphthalmia-associated transcription factor (MITF) mRNA is inhibited by coding region determinant-binding protein (CRD-BP).
Melanoma
Overexpression of mRNA-binding protein CRD-BP in malignant melanomas.
Melanoma
The initiator methionine tRNA drives cell migration and invasion leading to increased metastatic potential in melanoma.
Melanoma
The RNA-binding protein MEX3B mediates resistance to cancer immunotherapy by downregulating HLA-A expression.
Melanoma
West Nile Virus NS1 Antagonizes Interferon Beta Production by Targeting RIG-I and MDA5.
Melanoma, Experimental
Replicase-based plasmid DNA shows anti-tumor activity.
Melanoma, Experimental
[The mechanism of anti-tumor immune response against mouse melanoma to xenogeneic vaccination]
Memory Disorders
Associative and spatial learning and memory deficits in transgenic mice overexpressing the RNA-binding protein HuD.
Memory Disorders
Dendritic trafficking of BDNF mRNA is mediated by translin and blocked by the G196A (Val66Met) mutation.
Meningioma
Cytoplasmic overexpression of RNA-binding protein HuR is a marker of poor prognosis in meningioma, and HuR knockdown decreases meningioma cell growth and resistance to hypoxia.
Meningioma
Functional analysis of an alternatively spliced estrogen receptor lacking exon 4 isolated from MCF-7 breast cancer cells and meningioma tissue.
Meningitis, Aseptic
Genomic characterization of echovirus 6 causing aseptic meningitis in Hokkaido, Japan: a novel cluster in the nonstructural protein coding region of human enterovirus B.
Meningitis, Aseptic
Natural genetic recombination between co-circulating heterotypic enteroviruses.
Meningitis, Aseptic
Phylogenetic analysis of Echovirus 30 isolated during the 2005 outbreak in France reveals existence of multiple lineages and suggests frequent recombination events.
Meningitis, Fungal
Characterizing the role of RNA silencing components in Cryptococcus neoformans.
Mental Retardation, X-Linked
Modulation of neuritogenesis by a protein implicated in X-linked mental retardation.
Metabolic Diseases
Circular RNAs are a novel type of non-coding RNAs in ROS regulation, cardiovascular metabolic inflammations and cancers.
Metabolic Syndrome
Hepatitis C virus nonstructural protein 5A favors upregulation of gluconeogenic and lipogenic gene expression leading towards insulin resistance: a metabolic syndrome.
Metrorrhagia
Chimeras between oilseed rape mosaic virus and tobacco mosaic virus highlight the relevant role of the tobamoviral RdRp as pathogenicity determinant in several hosts.
Microcephaly
Congenital Visual Impairment and Progressive Microcephaly Due to Lysyl-Transfer Ribonucleic Acid (RNA) Synthetase (KARS) Mutations: The Expanding Phenotype of Aminoacyl-Transfer RNA Synthetase Mutations in Human Disease.
Microphthalmos
Functional Role of the RNA-Binding Protein Rbm24a and Its Target sox2 in Microphthalmia.
Molluscum Contagiosum
Similarity in genome organization between Molluscum contagiosum virus (MCV) and vaccinia virus (VV): identification of MCV homologues of the VV genes for protein kinase 2, structural protein VP8, RNA polymerase 35 kDa subunit and 3beta-hydroxysteroid dehydrogenase.
Motor Neuron Disease
ALS-causative mutations in FUS/TLS confer gain and loss of function by altered association with SMN and U1-snRNP.
Motor Neuron Disease
Mechanism of karyopherin-?2 binding and nuclear import of ALS variants FUS(P525L) and FUS(R495X).
Motor Neuron Disease
Senataxin, A Novel Helicase at the Interface of RNA Transcriptome Regulation and Neurobiology: From Normal Function to Pathological Roles in Motor Neuron Disease and Cerebellar Degeneration.
Motor Neuron Disease
The Small-Molecule Flunarizine in Spinal Muscular Atrophy Patient Fibroblasts Impacts on the Gemin Components of the SMN Complex and TDP43, an RNA-Binding Protein Relevant to Motor Neuron Diseases.
Mouth Diseases
(F)uridylylated Peptides Linked to VPg1 of Foot-and- Mouth Disease Virus (FMDV): Design, Synthesis and X-Ray Crystallography of the Complexes with FMDV RNA-Dependent RNA Polymerase.
Mouth Diseases
Development of a recombinant vaccine against foot and mouth disease utilizing mutant attenuated Listeria ivanovii strain as a live vector.
Mouth Diseases
Development of synthetic peptide ELISA based on nonstructural protein 2C of foot and mouth disease virus.
Mouth Diseases
Expression of enterovirus 71 capsid protein VP1 in Escherichia coli and its clinical application.
Mouth Diseases
GITRL as a genetic adjuvant enhances enterovirus 71 VP1 DNA vaccine immunogenicity.
Mouth Diseases
Homology Modeling and Analysis of Structure Predictions of the Bovine Rhinitis B Virus RNA Dependent RNA Polymerase (RdRp).
Mouth Diseases
Improved immunogenicity of a peptide epitope after fusion to hepatitis B core protein.
Mouth Diseases
Indirect ELISA using recombinant nonstructural protein 3D to detect foot and mouth disease virus infection associated antibodies.
Mouth Diseases
Induction of active immune suppression by co-immunization with DNA- and protein-based vaccines.
Mouth Diseases
Inhibitors of foot and mouth disease virus targeting a novel pocket of the RNA-dependent RNA polymerase.
Mouth Diseases
Isolation of novel sequences targeting highly variable viral protein hemagglutinin.
Mouth Diseases
Molecular characterization of amino acid deletion in VP1 (1D) protein and novel amino acid substitutions in 3D polymerase protein of foot and mouth disease virus subtype A/Iran87.
Mouth Diseases
Orientation of epitopes influences the immunogenicity of synthetic peptide dimers.
Mouth Diseases
Purification and immunogenicity of fusion VP1 protein of foot and mouth disease virus.
Mouth Diseases
Radioimmunoassay for detection of VP1 specific neutralizing antibodies of foot and mouth disease virus.
Mouth Diseases
The plasmid constructs producing shRNA corresponding to the conserved 3D polymerase of Foot and Mouth Disease virus protects guinea pigs against challenge virus.
Mouth Diseases
[Development and characterization of monoclonal antibodies against VP1 protein of AsiaI type foot-and-mouth virus]
Mouth Diseases
[Molecular basis of changes in biological properties of foot and mouth disease virus of subtype A22]
Mouth Diseases
[Primary structure of the A22 RNA polymerase gene of the foot and mouth disease virus]
Mouth Diseases
[Synthesis of new fragments of VP1 protein fragments from foot and mouth disease virus type A22. Synthesis of fragments 134-139, 134-145, 140-145, 150-155, and 150-159]
Mouth Neoplasms
Overexpression of RNA-binding protein CELF1 prevents apoptosis and destabilizes pro-apoptotic mRNAs in oral cancer cells.
Multiple Myeloma
Cyclin-dependent kinase inhibitor, P276-00 induces apoptosis in multiple myeloma cells by inhibition of Cdk9-T1 and RNA polymerase II-dependent transcription.
Multiple Myeloma
IL-6-induced enhancement of c-myc translation in multiple myeloma cells: critical role of cytoplasmic localization of the RNA-binding protein hnRNP A1.
Multiple Myeloma
IL-6-induced stimulation of c-myc translation in multiple myeloma cells is mediated by myc internal ribosome entry site function and the RNA-binding protein, hnRNP A1.
Multiple Myeloma
Seliciclib (CYC202, R-Roscovitine) induces cell death in multiple myeloma cells by inhibition of RNA polymerase II-dependent transcription and down-regulation of Mcl-1.
Multiple Sclerosis
Antibodies to the RNA-binding protein hnRNP A1 contribute to neurodegeneration in a model of central nervous system autoimmune inflammatory disease.
Multiple Sclerosis
Dysfunctional RNA-binding protein biology and neurodegeneration in experimental autoimmune encephalomyelitis in female mice.
Multiple Sclerosis
Neuronal RNA-binding protein dysfunction in multiple sclerosis cortex.
Multiple Sclerosis
Polymerase-1 pathway activation in acute multiple sclerosis relapse.
Multiple Sclerosis
Targeting the RNA-Binding Protein HuR Alleviates Neuroinflammation in Experimental Autoimmune Encephalomyelitis: Potential Therapy for Multiple Sclerosis.
Multiple Sclerosis
Unraveling a new player in multiple sclerosis pathogenesis: The RNA-binding protein HuR.
Mumps
Protein domain definition should allow for conditional disorder.
Mumps
RNA polymerase in mumps virion.
Mumps
The R2TP complex regulates paramyxovirus RNA synthesis.
Mumps
Viruses within the Flaviviridae decrease CD4 expression and inhibit HIV replication in human CD4+ cells.
Muscle Cramp
Cathelicidin antimicrobial peptides suppress EV71 infection via regulating antiviral response and inhibiting viral binding.
Muscular Atrophy
A de novo c.1509dupA:p.R503fs mutation of FUS: report of a girl with sporadic juvenile amyotrophic lateral sclerosis.
Muscular Atrophy
Muscle-specific Expression of the RNA-binding Protein Staufen1 Induces Progressive Skeletal Muscle Atrophy via Regulation of Phosphatase Tensin Homolog.
Muscular Atrophy, Spinal
The Small-Molecule Flunarizine in Spinal Muscular Atrophy Patient Fibroblasts Impacts on the Gemin Components of the SMN Complex and TDP43, an RNA-Binding Protein Relevant to Motor Neuron Diseases.
Muscular Diseases
Abnormal expression of RNA polymerase II-associated proteins in muscle of patients with myofibrillar myopathies.
Muscular Diseases
Developmental regulation of muscleblind-like (MBNL) gene expression in the chicken embryo retina.
Muscular Diseases
Immune Myopathy With Perimysial Pathology Associated With Interstitial Lung Disease and Anti-EJ Antibodies.
Muscular Diseases
Loss of RNA-Binding Protein Sfpq Causes Long-Gene Transcriptopathy in Skeletal Muscle and Severe Muscle Mass Reduction with Metabolic Myopathy.
Muscular Diseases
TDP-43 and RNA form amyloid-like myo-granules in regenerating muscle.
Muscular Dystrophies
Myo-granules Connect Physiology and Pathophysiology.
Muscular Dystrophies
Point mutations in the dystrophin gene: evidence for frequent use of cryptic splice sites as a result of splicing defects.
Muscular Dystrophies, Limb-Girdle
Myofibrillar disruption and RNA-binding protein aggregation in a mouse model of limb-girdle muscular dystrophy 1D.
Muscular Dystrophy, Oculopharyngeal
pH-dependent self-assembly of polyalanine peptides.
Myalgia
Haemolytic anaemia precipitated by dengue fever.
Mycoses
An automated high throughput filtration assay: application to polymerase inhibitor identification.
Mycoses
Control of brown patch (Rhizoctonia solani) in tall fescue (Festuca arundinacea Schreb.) by host induced gene silencing.
Mycoses
Molecular cloning and characterization of an inducible RNA-dependent RNA polymerase gene, GhRdRP, from cotton (Gossypium hirsutum L.).
Myelodysplastic Syndromes
Expression of EVI1 in myelodysplastic syndromes and other hematologic malignancies without 3q26 translocations.
Myelodysplastic Syndromes
RNA-binding protein (RBFOX1) inherited polymorphism rs8051518 is not associated with splice factor mutations in myelodysplastic syndromes and myeloproliferative neoplasms.
Myocardial Ischemia
CIRBP protects H9C2 cells against myocardial ischemia through inhibition of NF-?B pathway.
Myocarditis
Characterization of polyclonal antibodies against the capsid proteins of Ljungan virus.
Myocarditis
CVB3 Nonstructural 2A Protein Modulates SREBP1a Signaling via the MEK/ERK Pathway.
Myocarditis
Enteroviral RNA replication in the myocardium of patients with left ventricular dysfunction and clinically suspected myocarditis.
Myocarditis
Intein-mediated backbone cyclization of VP1 protein enhanced protection of CVB3-induced viral myocarditis.
Myocarditis
Proteome alterations in human host cells infected with coxsackievirus B3.
Myoclonus
Novel POLR1C mutation in RNA polymerase III-related leukodystrophy with severe myoclonus and dystonia.
Myoepithelioma
Cutaneous syncytial myoepithelioma: A case report with emphasis on the differential diagnosis of problematic dermal tumors.
Myositis
A case of macrophage activation syndrome in a patient with anti-synthetase syndrome.
Myositis
A rare association of anti-alanine-transfer RNA synthetase (anti-PL12) syndrome and sporadic inclusion body myositis.
Myositis
Antibody to threonyl-transfer RNA synthetase in myositis sera.
Myositis
Antisynthetase Syndrome with Anti-Jo1 Antibodies in 48 Patients: Pulmonary Involvement Predicts Disease-modifying Antirheumatic Drug Use.
Myositis
Clinical features of anti-synthetase syndrome associated interstitial lung disease: a retrospective cohort in China.
Myositis
Complete spinal cord involvement from neuromyelitis optica spectrum disorder in an adult female with anti-synthetase syndrome.
Myositis
Cutaneous manifestations of dermatomyositis characterized by myositis-specific autoantibodies.
Myositis
In adult onset myositis, the presence of interstitial lung disease and myositis specific/associated antibodies are governed by HLA class II haplotype, rather than by myositis subtype.
Myositis
Integrated Diagnosis Project for Inflammatory Myopathies: An association between autoantibodies and muscle pathology.
Myositis
Mechanic's hand; is it a prodromic sign of disease relapse of anti-synthetase syndrome; a case report.
Myositis
Mizoribine treatment in an elderly diabetic patient with antisynthetase-associated interstitial lung disease.
Myositis
Myo-granules Connect Physiology and Pathophysiology.
Myositis
Skeletal Muscle Involvement in Antisynthetase Syndrome.
Myositis
Statins and myotoxic effects associated with anti-3-hydroxy-3-methylglutaryl-coenzyme a reductase autoantibodies: an observational study in Japan.
Myositis
The clinical phenotype associated with myositis-specific and associated autoantibodies: A meta-analysis revisiting the so-called antisynthetase syndrome.
Myositis
The Diagnosis and Treatment of Antisynthetase Syndrome.
Myositis
Treatment of antisynthetase-associated interstitial lung disease with tacrolimus.
Myositis
[Antisynthetase myopathy].
Myositis
[Antisynthetase syndrome: a retrospective study of 14 patients].
Myositis
[Autoantibodies of Inflammatory Myopathies: Update].
Myositis, Inclusion Body
A rare association of anti-alanine-transfer RNA synthetase (anti-PL12) syndrome and sporadic inclusion body myositis.
Myositis, Inclusion Body
Myo-granules Connect Physiology and Pathophysiology.
Myositis, Inclusion Body
[Autoantibodies of Inflammatory Myopathies: Update].
Myotonic Dystrophy
Altered phosphorylation and intracellular distribution of a (CUG)n triplet repeat RNA-binding protein in patients with myotonic dystrophy and in myotonin protein kinase knockout mice.
Myotonic Dystrophy
Cardiac elav-type RNA-binding protein (ETR-3) binds to RNA CUG repeats expanded in myotonic dystrophy.
Myotonic Dystrophy
CELF1 Mediates Connexin 43 mRNA Degradation in Dilated Cardiomyopathy.
Myotonic Dystrophy
Correction of RNA-Binding Protein CUGBP1 and GSK3? Signaling as Therapeutic Approach for Congenital and Adult Myotonic Dystrophy Type 1.
Myotonic Dystrophy
Developmental regulation of muscleblind-like (MBNL) gene expression in the chicken embryo retina.
Myotonic Dystrophy
Elevation of RNA-binding protein CUGBP1 is an early event in an inducible heart-specific mouse model of myotonic dystrophy.
Myotonic Dystrophy
Identification of a (CUG)n triplet repeat RNA-binding protein and its expression in myotonic dystrophy.
Myotonic Dystrophy
Inhibition of cyclooxygenase-1 by nonsteroidal anti-inflammatory drugs demethylates MeR2 enhancer and promotes Mbnl1 transcription in myogenic cells.
Myotonic Dystrophy
LDB3 splicing abnormalities are specific to skeletal muscles of patients with myotonic dystrophy type 1 and alter its PKC binding affinity.
Myotonic Dystrophy
Nuclear localization of MBNL1: splicing-mediated autoregulation and repression of repeat-derived aberrant proteins.
Myotonic Dystrophy
Repeat recognition.
Myotonic Dystrophy
Staufen1s role as a splicing factor and a disease modifier in Myotonic Dystrophy Type I.
Myotonic Dystrophy
The RNA-binding protein CUGBP1 regulates stability of tumor necrosis factor mRNA in muscle cells: implications for myotonic dystrophy.
Myxoma
A myxoma virus nucleotide sequence with homology to the vaccinia virus RNA polymerase 22-kDa subunit gene.
Myxoma
RNA Polymerase Mutations Selected during Experimental Evolution Enhance Replication of a Hybrid Vaccinia Virus with an Intermediate Transcription Factor Subunit Replaced by the Myxoma Virus Ortholog.
Nasal Polyps
Cold-inducible RNA-binding protein contributes to tissue remodeling in chronic rhinosinusitis with nasal polyps.
Nasal Polyps
Expression of MicroRNA machinery proteins in different types of chronic rhinosinusitis.
Nasopharyngeal Carcinoma
Loss of Cirbp expression is correlated with the malignant progression and poor prognosis in nasopharyngeal carcinoma.
Nasopharyngeal Carcinoma
RBM24 suppresses cancer progression by upregulating miR-25 to target MALAT1 in nasopharyngeal carcinoma.
Nasopharyngeal Carcinoma
RNA-binding protein YBX1 promotes cell proliferation and invasiveness of nasopharyngeal carcinoma cells via binding to AURKA mRNA.
Neonatal Sepsis
C23, an oligopeptide derived from cold-inducible RNA-binding protein, suppresses inflammation and reduces lung injury in neonatal sepsis.
Neoplasm Metastasis
An RNA-binding protein, Hu-antigen R, in pancreatic cancer epithelial to mesenchymal transition, metastasis, and cancer stem cells.
Neoplasm Metastasis
Analysis of RNA-binding protein IMP3 to predict metastasis and prognosis of renal-cell carcinoma: a retrospective study.
Neoplasm Metastasis
Anti-Cancer Stem Cells Potentiality of an Anti-Malarial Agent Quinacrine: An Old Wine in a New Bottle.
Neoplasm Metastasis
Cell type-restricted activity of hnRNPM promotes breast cancer metastasis via regulating alternative splicing.
Neoplasm Metastasis
CircRNA circFOXK2 facilitates oncogenesis in breast cancer via IGF2BP3/miR-370 axis.
Neoplasm Metastasis
Clinicopathological Significance of TARBP2, APP, and ZNF395 in Breast Cancer.
Neoplasm Metastasis
CPEB1 mediates hepatocellular carcinoma cancer stemness and chemoresistance.
Neoplasm Metastasis
CSDE1 controls gene expression through the miRNA-mediated decay machinery.
Neoplasm Metastasis
Diffuse expression of RNA-binding protein IMP3 predicts high-stage lymph node metastasis and poor prognosis in colorectal adenocarcinoma.
Neoplasm Metastasis
EIF4E regulates STEAP1 expression in peritoneal metastasis.
Neoplasm Metastasis
Extracellular vesicle-dependent effect of RNA-binding protein IGF2BP1 on melanoma metastasis.
Neoplasm Metastasis
Heterogeneous nuclear ribonucleoprotein A2/B1 is a negative regulator of human breast cancer metastasis by maintaining the balance of multiple genes and pathways.
Neoplasm Metastasis
HNRNPLL stabilizes mRNA for DNA replication proteins and promotes cell cycle progression in colorectal cancer cells.
Neoplasm Metastasis
IMP3 RNP Safe Houses Prevent miRNA-Directed HMGA2 mRNA Decay in Cancer and Development.
Neoplasm Metastasis
Invasive growth associated with Cold-Inducible RNA-Binding Protein expression drives recurrence of surgically resected brain metastases.
Neoplasm Metastasis
Kallikrein 6 protease advances colon tumorigenesis via induction of the high mobility group A2 protein.
Neoplasm Metastasis
Long non-coding RNA Loc490 inhibits gastric cancer cell proliferation and metastasis by upregulating RNA-binding protein Quaking.
Neoplasm Metastasis
Long non-coding RNAs: a rising biotarget in colorectal cancer.
Neoplasm Metastasis
Msi1 promotes breast cancer metastasis by regulating invadopodia-mediated extracellular matrix degradation via the Timp3-Mmp9 pathway.
Neoplasm Metastasis
Musashi-2 (MSI2) regulates epidermal growth factor receptor (EGFR) expression and response to EGFR inhibitors in EGFR-mutated non-small cell lung cancer (NSCLC).
Neoplasm Metastasis
Prognostic alternative splicing regulatory network of RBM25 in hepatocellular carcinoma.
Neoplasm Metastasis
RBMS1 Suppresses Colon Cancer Metastasis through Targeted Stabilization of Its mRNA Regulon.
Neoplasm Metastasis
RNA-binding protein KHSRP promotes tumor growth and metastasis in non-small cell lung cancer.
Neoplasm Metastasis
RNA-binding protein SORBS2 suppresses clear cell renal cell carcinoma metastasis by enhancing MTUS1 mRNA stability.
Neoplasm Metastasis
Targeting the interaction between RNA-binding protein HuR and FOXQ1 suppresses breast cancer invasion and metastasis.
Neoplasm Metastasis
The Expression of RNA-Binding Protein HuR in Non-Small Cell Lung Cancer Correlates with Vascular Endothelial Growth Factor-C Expression and Lymph Node Metastasis.
Neoplasm Metastasis
The function of the RNA-binding protein hnRNP in cancer metastasis.
Neoplasm Metastasis
The initiator methionine tRNA drives cell migration and invasion leading to increased metastatic potential in melanoma.
Neoplasm Metastasis
The non-reverse transcriptase activity of the human telomerase reverse transcriptase promotes tumor progression (review).
Neoplasm Metastasis
The RNA-binding protein AKAP8 suppresses tumor metastasis by antagonizing EMT-associated alternative splicing.
Neoplasm Metastasis
The RNA-binding protein HuR inhibits expression of CCL5 and limits recruitment of macrophages into tumors.
Neoplasm Metastasis
The RNA-Binding Protein NELFE Promotes Gastric Cancer Growth and Metastasis Through E2F2.
Neoplasm Metastasis
The RNA-binding protein RBM47 inhibits non-small cell lung carcinoma metastasis through modulation of AXIN1 mRNA stability and Wnt/?-catentin signaling.
Neoplasm Metastasis
The RNA-binding protein SORBS2 suppresses hepatocellular carcinoma tumourigenesis and metastasis by stabilizing RORA mRNA.
Neoplasm Metastasis
The stability and oncogenic function of LIN28A are regulated by USP28.
Neoplasm Metastasis
Zinc finger RNA-binding protein promotes non-small-cell carcinoma growth and tumor metastasis by targeting the Notch signaling pathway.
Neoplasm Metastasis
[Relationship between expression of RBM38 and distant metastasis and prognosis of breast cancer].
Neoplasm Micrometastasis
The clinical importance of a transcription reverse-transcription concerted (TRC) diagnosis using peritoneal lavage fluids in gastric cancer with clinical serosal invasion: a prospective, multicenter study.
Neoplasms
1-(3-C-Ethynyl-beta-D-ribo-pentofuranosyl)cytosine (ECyd, TAS-106), a novel potent inhibitor of RNA polymerase, potentiates the cytotoxicity of CDDP in human cancer cells both in vitro and in vivo.
Neoplasms
3p21.3 tumor suppressor gene RBM5 inhibits growth of human prostate cancer PC-3 cells through apoptosis.
Neoplasms
A dead end for microRNAs.
Neoplasms
A forward genetic screen reveals novel independent regulators of ULBP1, an activating ligand for natural killer cells.
Neoplasms
A global integrated analysis of UNC5C down-regulation in cancers: insights from mechanism and combined treatment strategy.
Neoplasms
A novel RNA-binding protein, Ossa/C9orf10, regulates activity of Src kinases to protect cells from oxidative stress-induced apoptosis.
Neoplasms
A Pleiotropic RNA-Binding Protein Controls Distinct Cell Cycle Checkpoints to Drive Resistance of p53-Defective Tumors to Chemotherapy.
Neoplasms
A proposed reverse transcription mechanism for (CAG)n and similar expandable repeats that cause neurological and other diseases.
Neoplasms
A renal cell carcinoma with EWSR1-TFE3 fusion gene.
Neoplasms
A SMYD3 Small-Molecule Inhibitor Impairing Cancer Cell Growth.
Neoplasms
Abnormal expression of TFIIIB subunits and RNA Pol III genes is associated with hepatocellular carcinoma.
Neoplasms
AC-Caps: Attention Based Capsule Network for Predicting RBP Binding Sites of LncRNA.
Neoplasms
Accelerated onset of viral transcription in adenovirus-infected HeLa cells treated with the tumor promoter 12-O-tetradecanoyl-phorbol-13-acetate.
Neoplasms
Activation of monocytes by three OspA vaccine candidates: lipoprotein OspA is a potent stimulator of monokines.
Neoplasms
Active Center Control of Termination by RNA Polymerase III and tRNA Gene Transcription Levels In Vivo.
Neoplasms
Advances at the Interface of Cancer and Systemic Sclerosis.
Neoplasms
Alpha CP-4, encoded by a putative tumor suppressor gene at 3p21, but not its alternative splice variant alpha CP-4a, is underexpressed in lung cancer.
Neoplasms
Altered chaperone and protein turnover regulators expression in cultured skin fibroblasts from type 1 diabetes mellitus with nephropathy.
Neoplasms
An antimutagenic metabolite, streptovaricin C, isolated from Streptomyces sp.
Neoplasms
An emerging role for nuclear RNA-mediated responses to genotoxic stress.
Neoplasms
An Integrative Drug Repurposing Pipeline: Switching Viral Drugs to Breast Cancer.
Neoplasms
An OTU deubiquitinating enzyme in Eimeria tenella interacts with Eimeria tenella virus RDRP.
Neoplasms
An RNA-binding protein, Hu-antigen R, in pancreatic cancer epithelial to mesenchymal transition, metastasis, and cancer stem cells.
Neoplasms
ANOVA, a putative astrocytic RNA-binding protein gene that maps to chromosome 19q13.3.
Neoplasms
Anti-cancer effects of the HuR inhibitor, MS-444, in malignant glioma cells.
Neoplasms
Anti-Cancer Stem Cells Potentiality of an Anti-Malarial Agent Quinacrine: An Old Wine in a New Bottle.
Neoplasms
Antigenically active nonhistone chromatin proteins in cancer cells.
Neoplasms
Antitumor activity of tumor-targeted RNA replicase-based plasmid that expresses interleukin-2 in a murine melanoma model.
Neoplasms
Antiviral protective immunity induced by major histocompatibility complex class I molecule-restricted viral T-lymphocyte epitopes inserted in various positions in immunologically self and nonself proteins.
Neoplasms
Applying a high-throughput fluorescence polarization assay for the discovery of chemical probes blocking La:RNA interactions in vitro and in cells.
Neoplasms
Arid5a Promotes Immune Evasion by Augmenting Tryptophan Metabolism and Chemokine Expression.
Neoplasms
Arid5a: A Missing Link between EMT and Tumoral Immune Resistance.
Neoplasms
Binding of Escherichia coli RNA polymerase to a specific site located near the 3'-end of the avaian sarcoma virus genome.
Neoplasms
Bioinformatics analysis identifies potential chemoresistance-associated genes across multiple types of cancer.
Neoplasms
Biological Roles and Mechanisms of Circular RNA in Human Cancers.
Neoplasms
Biphasic and Stage-Associated Expression of CPEB4 in Hepatocellular Carcinoma.
Neoplasms
BRF1 accelerates prostate tumourigenesis and perturbs immune infiltration.
Neoplasms
BRUCE regulates DNA double-strand break response by promoting USP8 deubiquitination of BRIT1.
Neoplasms
CDK1 dependent phosphorylation of hTERT contributes to cancer progression.
Neoplasms
Che-1 is targeted by c-Myc to sustain proliferation in pre-B-cell acute lymphoblastic leukemia.
Neoplasms
CHOP/GADD153 and methionyl-tRNA synthetase (MetRS) genes overlap in a conserved region that controls mRNA stability.
Neoplasms
Chromatin-directed Ribonucleic Acid Synthesis: A Comparison of Chromatins Isolated from Healthy, Avirulent Agrobacterium tumefaciens Inoculated, and Crown-Gall Tumor Tissues of Vicia faba.
Neoplasms
CircRNA-protein complexes: IMP3 protein component defines subfamily of circRNPs.
Neoplasms
Circular RNA La-related RNA-binding protein 4 correlates with reduced tumor stage, as well as better prognosis, and promotes chemosensitivity to doxorubicin in breast cancer.
Neoplasms
Circular RNAs are a novel type of non-coding RNAs in ROS regulation, cardiovascular metabolic inflammations and cancers.
Neoplasms
Circular RNAs function as competing endogenous RNAs in multiple types of cancer.
Neoplasms
Circular RNAs: Characteristics, function, and role in human cancer.
Neoplasms
Close temporal relationship between onset of cancer and scleroderma in patients with RNA polymerase I/III antibodies.
Neoplasms
Combined inhibition of RNA polymerase I and mTORC1/2 synergize to combat oral squamous cell carcinoma.
Neoplasms
Comparative analysis of inducible expression systems in transient transfection studies.
Neoplasms
Compensatory RNA polymerase 2 loading determines the efficacy and transcriptional selectivity of JQ1 in Myc-driven tumors.
Neoplasms
Complex HuR function in pancreatic cancer cells.
Neoplasms
Computer-Aided Discovery of Small Molecules Targeting the RNA Splicing Activity of hnRNP A1 in Castration-Resistant Prostate Cancer.
Neoplasms
Control of parvovirus DNA replication by a tetracycline-regulated repressor.
Neoplasms
Correction for Bhowmick et al., "Rotavirus-Encoded Nonstructural Protein 1 Modulates Cellular Apoptotic Machinery by Targeting Tumor Suppressor Protein p53".
Neoplasms
Correction for Gabai et al., "Heat Shock Transcription Factor Hsf1 Is Involved in Tumor Progression via Regulation of Hypoxia-Inducible Factor 1 and RNA-Binding Protein HuR".
Neoplasms
Cortisone inhibition of nuclear RNA polymerase of the human neoplasm, H. Emb. Rh. number 1, transplanted in rats.
Neoplasms
CPEB1 mediates hepatocellular carcinoma cancer stemness and chemoresistance.
Neoplasms
CREB targets define the gene expression signature of malignancies having reduced levels of the tumor suppressor tristetraprolin.
Neoplasms
Crimean-Congo hemorrhagic fever virus-encoded ovarian tumor (OTU) protease activity is dispensable for virus RNA polymerase function.
Neoplasms
Critical role of tristetraprolin and AU-rich element RNA-binding protein 1 in the suppression of cancer cell growth by globular adiponectin.
Neoplasms
Cryptotanshinone, a novel tumor angiogenesis inhibitor, destabilizes tumor necrosis factor-? mRNA via decreasing nuclear-cytoplasmic translocation of RNA-binding protein HuR.
Neoplasms
Crystal structure of the human heterogeneous ribonucleoprotein A18 RNA-recognition motif.
Neoplasms
CSDE1 controls gene expression through the miRNA-mediated decay machinery.
Neoplasms
CX-5461-loaded nucleolus-targeting nanoplatform for cancer therapy through induction of pro-death autophagy.
Neoplasms
Cytokine gene expression in rejecting and tolerant rat lung allograft models: analysis by RT-PCR.
Neoplasms
Cytokine gene expression in skin and lymphoid organs in graft versus host disease.
Neoplasms
DDX3 regulates endoplasmic reticulum stress-induced ATF4 expression.
Neoplasms
Design and Construction of Aroyl-Hydrazone Derivatives: Synthesis, Crystal Structure, Molecular Docking and Their Biological Activities.
Neoplasms
Design, synthesis and anticancer activity of fluorocyclopentenyl-purines and - pyrimidines.
Neoplasms
Detection of hepatitis C virus NS5 protein and genome in Chinese carcinoma of the extrahepatic bile duct and its significance.
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Differential expression of PIWIL2 in papillary thyroid cancers.
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Differential expression of the TFIIIB subunits Brf1 and Brf2 in cancer cells.
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Dihydrotanshinone-I interferes with the RNA-binding activity of HuR affecting its post-transcriptional function.
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Direct Regulation of Alternative Splicing by SMAD3 through PCBP1 Is Essential to the Tumor-Promoting Role of TGF-?.
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Distinct roles for the RNA-binding protein Staufen1 in prostate cancer.
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DNA dependent RNA polymerase from Ehrlich ascites tumor cells. II. Factors stimulating the activity of RNA polymerase II.
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DNA dependent RNA polymerase from ehrlich ascites tumor cells. IV. A novel protein repressing RNA polymerase II.
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DNA dependent RNA polymerase from Ehrlich ascites tumor cells. V. Characterization of a factor repressing RNA polymerase II as a ribonucleoprotein.
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DNA methylation in the promoter of ribosomal RNA genes in human cells as determined by genomic sequencing.
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DNA-dependent RNA polymerase from Ehrlich ascites tumor cells. I. Partial purification and characterization of RNA polymerase II.
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DNA-dependent RNA polymerases of Ehrlich carcinoma, other murine ascites tumors, and murine normal tissues.
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DND1 maintains germline stem cells via recruitment of the CCR4-NOT complex to target mRNAs.
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Down-regulation of the retinoblastoma tumor suppressor by the hepatitis C virus NS5B RNA-dependent RNA polymerase.
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Downregulation of Msi1 suppresses the growth of human colon cancer by targeting p21cip1.
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Downregulation of tumor suppressor QKI in gastric cancer and its implication in cancer prognosis.
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Dysregulated transcription across diverse cancer types reveals the importance of RNA-binding protein in carcinogenesis.
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Dysregulation of the basal RNA polymerase transcription apparatus in cancer.
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EBF1-Mediated Upregulation of Ribosome Assembly Factor PNO1 Contributes to Cancer Progression by Negatively Regulating the p53 Signaling Pathway.
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Editorial retraction. Down-regulation of human telomerase reverse transcriptase through anti-c-myc siRNA in human colon cancer Colo 320 cells.
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Effect of all-trans-retinoic acid on nuclear RNA polymerase activity in chemically-induced rat mammary tumors.
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Effect of cis-diamminedichloroplatinum(II) and other platinum compounds on the RNA polymerase reaction.
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Effect of RNA tumor virus-specific protein p30 on reverse transcriptase. Intraspecies and interspecies interaction between reverse transcriptase and p30.
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Effect of sex hormones on RNA synthesis of androgen-dependent mouse mammary tumor (Shionogi carcinoma).
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Effect of tumour growth on hepatic neutral ribonuclease and its inhibitor and on RNA polymerase activity of liver nuclei.
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Elevated dengue virus nonstructural protein 1 serum levels and altered toll-like receptor 4 expression, nitric oxide, and tumor necrosis factor alpha production in dengue hemorrhagic Fever patients.
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Elevated FUS/TLS expression is negatively associated with E-cadherin expression and prognosis of patients with non-small cell lung cancer.
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Elevated Heterogeneous Nuclear Ribonucleoprotein C Expression Correlates With Poor Prognosis in Patients With Surgically Resected Lung Adenocarcinoma.
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Elevated Hu-Antigen Receptor (HuR) Expression is Associated with Tumor Aggressiveness and Poor Prognosis but not with COX-2 Expression in Invasive Breast Carcinoma Patients.
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Elevated tRNA(iMet) synthesis can drive cell proliferation and oncogenic transformation.
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Emerging roles of RNA and RNA-binding protein network in cancer cells.
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Enhanced RNA polymerase III-dependent transcription is required for oncogenic transformation.
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Enzyme-linked immunosorbent assay for p16(INK4a) - a new triage test for the detection of cervical intraepithelial neoplasia?
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Epigenetic inactivation of the splicing RNA-binding protein CELF2 in human breast cancer.
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Estrogen-dependent in vitro stimulation of RNA synthesis in hormone-dependent mammary tumors of the rat.
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ETMR: a tumor entity in its infancy.
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ETV6/RUNX1 transcript is a target of RNA-binding protein IGF2BP1 in t(12;21)(p13;q22)-positive acute lymphoblastic leukemia.
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Eukaryotic initiation Factor 4AIII facilitates hepatocellular carcinoma cell proliferation, migration, and epithelial-mesenchymal transition process via antagonistically binding to WD repeat domain 66 with miRNA-2113.
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EWS represses cofilin 1 expression by inducing nuclear retention of cofilin 1 mRNA.
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EWSR1 and ATF1 rearrangements in clear cell odontogenic carcinoma: presentation of a case.
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Exploring a common mechanism of alcohol-induced deregulation of RNA Pol III genes in liver and breast cells.
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Exploring the Allosteric Territory of Protein Function.
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Exploring the molecular basis of RNA recognition by the dimeric RNA-binding protein via molecular simulation methods.
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Expression of a truncated form of the c-Kit tyrosine kinase receptor and activation of Src kinase in human prostatic cancer.
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Expression of cold-inducible RNA-binding protein (CIRP) in pituitary adenoma and its relationships with tumor recurrence.
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Expression of insulin-like growth factor II mRNA-binding protein 3 predicts early recurrence and poor prognosis in intrahepatic cholangiocarcinoma.
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Expression of La Ribonucleoprotein Domain Family Member 4B (LARP4B) in Liver Cancer and Their Clinical and Prognostic Significance.
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Expression of RNA-binding protein IMP3 (KOC) in benign urothelium and urothelial tumors.
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Expression of the neural RNA-binding protein Musashi1 in human gliomas.
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Expression of the Neural RNA-binding protein Musashi1 in pediatric brain tumors.
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Expression of the oncofetal protein IGF2BP3 in endometrial clear cell carcinoma: assessment of frequency and significance.
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Expression of the RNA-binding protein CRD-BP in brain and non-small cell lung tumors.
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Expression of the RNA-binding protein VICKZ in normal hematopoietic tissues and neoplasms.
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Expression polymerase chain reaction: a sensitive method for analysis of gene expression in human tumours.
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Expression profile, clinical significance, and biological function of insulin-like growth factor 2 messenger RNA-binding proteins in non-small cell lung cancer.
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Expression, Intracellular Localization, and Prognostic Value of Plasminogen Activator Inhibitor 1 and PAI-1 RNA-Binding Protein 1 in Primary and Recurrent Ovarian Cancer: A Study of the Tumor Bank Ovarian Cancer Network.
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Extracellular vesicle-dependent effect of RNA-binding protein IGF2BP1 on melanoma metastasis.
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Extrapulmonary small cell carcinomas express K homology domain containing protein overexpressed in cancer, but carcinoid tumors do not.
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FXR1 expression domain in Wilms tumor.
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G3BP1 and G3BP2 regulate translation of interferon-stimulated genes: IFITM1, IFITM2 and IFITM3 in the cancer cell line MCF7.
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Gender Specific Differences in RNA Polymerase III Transcription.
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Gene expression of erythropoietin in hepatocellular carcinoma.
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Gene expression of mutant erythropoietin in hepatocellular carcinoma.
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Gene-editing by CRISPR-Cas9 in combination with anthracycline therapy via tumor microenvironment-switchable, EGFR-targeted, and nucleus-directed nanoparticles for head and neck cancer suppression.
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Genes Associated with Calcium Signaling are Involved in Alcohol-Induced Breast Cancer Growth.
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Genetic Mapping with Multiple Levels of Phenotypic Information Reveals Determinants of Lymphocyte Glucocorticoid Sensitivity.
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Genomic analyses of the RNA-binding protein Hu antigen R (HuR) identify a complex network of target genes and novel characteristics of its binding sites.
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Genomic characterization of a novel dsRNA virus detected in the phytopathogenic fungus Verticillium dahliae Kleb.
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GPRC5A is a potential oncogene in pancreatic ductal adenocarcinoma cells that is upregulated by gemcitabine with help from HuR.
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Growth complementation of influenza virus temperature-sensitive mutants in mouse cells which express the RNA polymerase and nucleoprotein genes.
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Heat shock transcription factor Hsf1 is involved in tumor progression via regulation of hypoxia-inducible factor 1 and RNA-binding protein HuR.
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Hepatic Premalignant Alterations Triggered by Human Nephrotoxin Aristolochic Acid I in Canines.
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Hepatitis C virus induces E6AP-dependent degradation of the retinoblastoma protein.
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Hepatitis C virus nonstructural protein 5A inhibits tumor necrosis factor-alpha-mediated apoptosis in Huh7 cells.
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Hepatitis C virus nonstructural protein NS4B transforms NIH3T3 cells in cooperation with the Ha-ras oncogene.
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Heterogeneous nuclear ribonucleoprotein A2/B1 is a negative regulator of human breast cancer metastasis by maintaining the balance of multiple genes and pathways.
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Heterogeneous nuclear ribonucleoprotein B1 expression in malignant mesothelioma.
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High expression of cytoplasmic polyadenylation element-binding protein 4 correlates with poor prognosis of patients with colorectal cancer.
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High expression of interleukin-enhancer binding factor 3 predicts poor prognosis in patients with lung adenocarcinoma.
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High expression of neuro-oncological ventral antigen 1 correlates with poor prognosis in hepatocellular carcinoma.
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High expression of spermatogenesis associated serine rich 2 promotes tumorigenicity in esophageal squamous cell carcinoma cells and is associated with poor patient prognosis.
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High expression of the RNA-binding protein RBPMS2 in gastrointestinal stromal tumors.
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High LIN28A Expressing Ovarian Cancer Cells Secrete Exosomes That Induce Invasion and Migration in HEK293 Cells.
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High-grade neuroendocrine carcinomas of the lung express K homology domain containing protein overexpressed in cancer but carcinoid tumors do not.
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hnRNP K suppresses apoptosis independent of p53 status by maintaining high levels of endogenous caspase inhibitors.
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HNRNPH1 is required for rhabdomyosarcoma cell growth and survival.
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hnRNPK-regulated LINC00263 promotes malignant phenotypes through miR-147a/CAPN2.
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How Ribosomes Translate Cancer.
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Hu antigen R (HuR) heterogeneous expression quantification as a prognostic marker of melanoma.
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Human Antigen R Binding and Regulation of SOX2 mRNA in Human Mesenchymal Stem Cells.
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Human La Protein: An RNA-Binding Protein Involved in Ovarian Cancer Development and Multidrug Resistance.
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Human oncoprotein Musashi-2 N-terminal RNA recognition motif backbone assignment and identification of RNA-binding pocket.
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Human RNA polymerase II-associated factor complex: dysregulation in cancer.
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Human somatic cell mutagenesis creates genetically tractable sarcomas.
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HuR and the bioenergetic signature of breast cancer: a low tumor expression of the RNA-binding protein predicts a higher risk of disease recurrence.
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HuR is a post-transcriptional regulator of core metabolic enzymes in pancreatic cancer.
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HuR mediates motility of human bone marrow-derived mesenchymal stem cells triggered by sphingosine 1-phosphate in liver fibrosis.
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HuR posttranscriptionally regulates WEE1: implications for the DNA damage response in pancreatic cancer cells.
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HuR Reduces Radiation-Induced DNA Damage by Enhancing Expression of ARID1A.
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HuR Small-Molecule Inhibitor Elicits Differential Effects in Adenomatosis Polyposis and Colorectal Carcinogenesis.
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HuR-targeted nanotherapy in combination with AMD3100 suppresses CXCR4 expression, cell growth, migration and invasion in lung cancer.
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HuR-targeted small molecule inhibitor exhibits cytotoxicity towards human lung cancer cells.
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HuR/ELAVL1 drives malignant peripheral nerve sheath tumor growth and metastasis.
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Identification of a novel splice variant of the human musashi-1 gene.
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Identification of novel human tumor cell-specific CaMK-II variants.
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Identification of RNA-binding protein LARP4B as a tumor suppressor in glioma.
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IGF2BP1: a novel binding protein of p38 MAPK.
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IGF2BP3 (IMP3) expression in angiosarcoma, epithelioid hemangioendothelioma, and benign vascular lesions.
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IGF2BP3 facilitates cell proliferation and tumorigenesis via modulation of JAK/STAT signalling pathway in human bladder cancer.
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Immunohistochemical Analysis Revealed a Correlation between Musashi-2 and Cyclin-D1 Expression in Patients with Oral Squamous Cells Carcinoma.
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IMP3 RNP Safe Houses Prevent miRNA-Directed HMGA2 mRNA Decay in Cancer and Development.
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Implication of RNA-binding protein La in proliferation, migration and invasion of lymph node-metastasized hypopharyngeal SCC cells.
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IMPs: an RNA-binding protein family that provides a link between stem cell maintenance in normal development and cancer.
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In vitro transcription of wound tumor virus RNA by virion-associated RNA transcriptase.
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Increased expression of insulin-like growth factor-II messenger RNA-binding protein 1 is associated with tumor progression in patients with lung cancer.
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Increased mediator complex subunit 15 expression is associated with poor prognosis in hepatocellular carcinoma.
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Increased TIA-1 gene expression in the tumor microenvironment after locoregional administration of tumor necrosis factor-alpha to patients with soft tissue limb sarcoma.
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Inhibition of BET proteins impairs estrogen-mediated growth and transcription in breast cancers by pausing RNA polymerase advancement.
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Inhibition of intrahepatic gamma interferon production by hepatitis C virus nonstructural protein 5A in transgenic mice.
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Inhibition of mammalian and oncornavirus nucleic acid polymerase activities by alkoxybenzophenanthridine alkaloids.
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Inhibition of nuclear DNA-dependent RNA polymerases from mouse ascites tumors and liver by glycerol.
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Inhibition of ribonucleases by ribonucleotides and transition state analogs in cell-free extracts from Ehrlich ascites tumor cells.
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Inhibition of RNA polymerase III transcription by Triptolide attenuates colorectal tumorigenesis.
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Insights from HuR biology point to potential improvement for second-line ovarian cancer therapy.
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Insulin-like growth factor 2 mRNA binding protein 3 (IGF2BP3) promotes lung tumorigenesis via attenuating p53 stability.
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Insulin-like growth factor II messenger RNA-binding protein 3 expression in gastrointestinal mesenchymal tumors.
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Insulin-like Growth Factor II Messenger RNA-binding Protein 3 in Salivary Gland Tumors.
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Insulin-Like Growth Factor II mRNA-Binding Protein 3 Expression Correlates with Poor Prognosis in Acral Lentiginous Melanoma.
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Insulin-like growth factor II mRNA-binding protein 3 expression promotes tumor formation and invasion and predicts poor prognosis in oral squamous cell carcinoma.
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Insulin-like growth factor II-messenger RNA-binding protein-3 and lung cancer.
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Integrative genomic analyses of the RNA-binding protein, RNPC1, and its potential role in cancer prediction.
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Interaction of the hepatitis B virus X protein with the lysine methyltransferase SET and MYND domain-containing 3 induces activator protein 1 activation.
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Intracellular functions of RNA-binding protein, Musashi1, in stem and cancer cells.
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Intratumoral anti-HuD immunotoxin therapy for small cell lung cancer and neuroblastoma.
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Invasive growth associated with Cold-Inducible RNA-Binding Protein expression drives recurrence of surgically resected brain metastases.
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Knockdown of Hnrnpa0, a del(5q) gene, alters myeloid cell fate in murine cells through regulation of AU-rich transcripts.
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Knockdown of MSI1 inhibited the cell proliferation of human osteosarcoma cells by targeting p21 and p27.
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L523S, an RNA-binding protein as a potential therapeutic target for lung cancer.
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La protein contributes to cells proliferation and migration and serves as a potential therapeutic target for hepatocellular carcinoma.
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Large-scale analysis of genome and transcriptome alterations in multiple tumors unveils novel cancer-relevant splicing networks.
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LARP1 isoform expression in human cancer cell lines.
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Leptin, Adiponectin, and Sam68 in Bone Metastasis from Breast Cancer.
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Lin28 induces epithelial-to-mesenchymal transition and stemness via downregulation of let-7a in breast cancer cells.
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LIN28 Is Selectively Expressed by Primordial and Pre-Meiotic Germ Cells in the Human Fetal Ovary.
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Lin28, a major translation reprogramming factor, gains access to YB-1-packaged mRNA through its cold-shock domain.
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Lin28A enhances chemosensitivity of colon cancer cells to 5-FU by promoting apoptosis in a let-7 independent manner.
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LIN28A Modulates Splicing and Gene Expression Programs in Breast Cancer Cells.
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LIN28B enhanced tumorigenesis in an autochthonous KRAS
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LIN28B promotes the progression of colon cancer by increasing B-cell lymphoma 2 expression.
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LINC00680 and TTN-AS1 Stabilized by EIF4A3 Promoted Malignant Biological Behaviors of Glioblastoma Cells.
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LncRNA SNHG1 and RNA binding protein hnRNPL form a complex and coregulate CDH1 to boost the growth and metastasis of prostate cancer.
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Long non-coding RNA DBH-AS1 promotes cancer progression in diffuse large B-cell lymphoma by targeting FN1 via RNA-binding protein BUD13.
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Long noncoding RNA SOX2OT promotes the proliferation of pancreatic cancer by binding to FUS.
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Loss of RNA-Binding Protein RBMS1 Promotes a Metastatic Transcriptional Program in Colorectal Cancer.
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Loss of TARBP2 Drives the Progression of Hepatocellular Carcinoma via miR-145-SERPINE1 Axis.
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Lower expression of LINC00092 in lung adenocarcinoma might mean poorer prognosis: A study based on data mining and bioinformatics.
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Mammary tumor induction in transgenic mice expressing an RNA-binding protein.
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Mapping the Transcriptome-Wide Landscape of RBP Binding Sites Using gPAR-CLIP-seq: Bioinformatic Analysis.
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Marek's Disease Virus (Gallid alphaherpesvirus 2)-Encoded miR-M2-5p Simultaneously Promotes Cell Proliferation and Suppresses Apoptosis Through RBM24 and MYOD1-Mediated Signaling Pathways.
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MBNL2 Regulates DNA Damage Response via Stabilizing p21.
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MCG10, a novel p53 target gene that encodes a KH domain RNA-binding protein, is capable of inducing apoptosis and cell cycle arrest in G(2)-M.
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Mechanisms of transcriptional regulation by WT1 (Wilms' tumour 1).
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Merkel cell carcinoma expresses K homology domain-containing protein overexpressed in cancer similar to other high-grade neuroendocrine carcinomas.
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Merkel Cell Polyomavirus Small T Antigen Is Oncogenic in Transgenic Mice.
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Merlin, a tumor suppressor, interacts with transactivation-responsive RNA-binding protein and inhibits its oncogenic activity.
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Methylcholanthrene induced murine primitive neuroectodermal tumor: ultrastructure and nuclear RNA polymerase activity.
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MicroRNA profiling in human diploid fibroblasts uncovers miR-519 role in replicative senescence.
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microRNA-18a induces apoptosis in colon cancer cells via the autophagolysosomal degradation of oncogenic heterogeneous nuclear ribonucleoprotein A1.
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Mild hypothermia facilitates the expression of cold-inducible RNA-binding protein and heat shock protein 70.1 in mouse brain.
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Mining Database for the Clinical Significance and Prognostic Value of ESRP1 in Cutaneous Malignant Melanoma.
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miR-181b functions as an oncomiR in colorectal cancer by targeting PDCD4.
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miR-200/375 control epithelial plasticity-associated alternative splicing by repressing the RNA-binding protein Quaking.
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MiR-4282 inhibits tumor progression through down-regulation of ZBTB2 by targeting LIN28B in oral squamous cell carcinoma.
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miR-519 suppresses tumor growth by reducing HuR levels.
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Molecular analysis of malignant triton tumors.
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Molecular detection of microscopic and submicroscopic deletions associated with Miller-Dieker syndrome.
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Molecular pathways: rodent parvoviruses--mechanisms of oncolysis and prospects for clinical cancer treatment.
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Morphoregulatory functions of the RNA-binding motif protein 3 in cell spreading, polarity and migration.
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Mouse DNA polymerase accompanied by a novel RNA polymerase activity: purification and partial characterization.
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Msi1 promotes tumor growth and cell proliferation by targeting cell cycle checkpoint proteins p21, p27 and p53 in cervical carcinomas.
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Msi1 promotes tumor progression by epithelial-to-mesenchymal transition in cervical cancer.
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MSI2-TGF-?/TGF-? R1/SMAD3 positive feedback regulation in glioblastoma.
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Multi-omics analysis of tumor mutation burden combined with immune infiltrates in melanoma.
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Multilevel prioritization of gene regulators associated with consensus molecular subtypes of colorectal cancer.
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Multiple functions of HuR in urinary tumors.
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Multiple Functions of the RNA-Binding Protein HuR in Cancer Progression, Treatment Responses and Prognosis.
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Multiple Mechanisms Inactivate the LIN-41 RNA-Binding Protein To Ensure a Robust Oocyte-to-Embryo Transition in Caenorhabditis elegans.
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Murine double minute 2 regulates Hu antigen R stability in human liver and colon cancer through NEDDylation.
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Musashi 2 contributes to the stemness and chemoresistance of liver cancer stem cells via LIN28A activation.
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Musashi RNA-binding protein 2 regulates estrogen receptor 1 function in breast cancer.
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Musashi-1-A Stemness RBP for Cancer Therapy?
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Musashi-2 (MSI2) regulates epidermal growth factor receptor (EGFR) expression and response to EGFR inhibitors in EGFR-mutated non-small cell lung cancer (NSCLC).
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Musashi-2 is a prognostic marker for the survival of patients with cervical cancer.
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Musashi-2, a novel oncoprotein promoting cervical cancer cell growth and invasion, is negatively regulated by p53-induced miR-143 and miR-107 activation.
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Musashi1 enhances chemotherapy resistance of pediatric glioblastoma cells in vitro.
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Musashi1 Impacts Radio-Resistance in Glioblastoma by Controlling DNA-Protein Kinase Catalytic Subunit.
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Musashi1, an evolutionarily conserved neural RNA-binding protein, is a versatile marker of human glioma cells in determining their cellular origin, malignancy, and proliferative activity.
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Muscone derivative ZM-32 inhibits breast tumor angiogenesis by suppressing HuR-mediated VEGF and MMP9 expression.
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NEDDylation in liver cancer: The regulation of the RNA binding protein Hu antigen R.
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NF-?B2/p52:c-Myc:hnRNPA1 Pathway Regulates Expression of Androgen Receptor Splice Variants and Enzalutamide Sensitivity in Prostate Cancer.
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No Matter How You Splice It, RBM39 Inhibition Targets Spliceosome Mutant AML.
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Nonstructural protein 5B promotes degradation of the NORE1A tumor suppressor to facilitate hepatitis C virus replication.
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Novel polypyridyl ruthenium complexes acting as high affinity DNA intercalators, potent transcription inhibitors and antitumor reagents.
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Novel roles for LIX1L in promoting cancer cell proliferation through ROS1-mediated LIX1L phosphorylation.
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Nuclear factor 90 promotes angiogenesis by regulating HIF-1?/VEGF-A expression through the PI3K/Akt signaling pathway in human cervical cancer.
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Nucleic acids from subcellular fractions of N-nitrosodiethylamine-induced hepatoma in mice.
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On the border of the amyloidogenic sequences: prefix analysis of the parallel beta sheets in the PDB_Amyloid collection.
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Ovarian tumor cell detection in peripheral blood progenitor cells harvests by RT-PCR.
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Overexpression of miR-20a promotes the progression of osteosarcoma by directly targeting QKI2.
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Overexpression of RNA-binding protein CELF1 prevents apoptosis and destabilizes pro-apoptotic mRNAs in oral cancer cells.
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p53 represses RNA polymerase III transcription by targeting TBP and inhibiting promoter occupancy by TFIIIB.
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Paraneoplastic Scleroderma: Are There Any Clues?
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Partial purification and characterization of RNA polymerase from nuclei of Ehrlich ascites tumor cells.
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Pathogenic mechanisms and the potential clinical value of circFoxo3 in cancers.
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Phase II study of TAS-106 in patients with platinum-failure recurrent or metastatic head and neck cancer and nasopharyngeal cancer.
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Phenylglyoxal as a template site-specific reagent for DNA and RNA polymerases. Selective inhibition of initiation.
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Phosphorylation of OGFOD1 by Cell Cycle-Dependent Kinase 7/9 Enhances the Transcriptional Activity of RNA Polymerase II in Breast Cancer Cells.
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Phosphorylation of the activation loop of gamma p21-activated kinase (gamma-Pak) and related kinases (MSTs) in normal and stressed neutrophils.
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PNO1 regulates autophagy and apoptosis of hepatocellular carcinoma via the MAPK signaling pathway.
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Porcine transmissible gastroenteritis virus nonstructural protein 2 contributes to inflammation via NF-?B activation.
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Posttranscriptional gene expression regulation in CpG-activated macrophages depends on FXR1P RNA-binding protein.
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Posttranscriptional regulation of cancer traits by HuR.
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Potency of a Scalable Nanoparticulate Subunit Vaccine.
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Potential role of LINC00996 in colorectal cancer: a study based on data mining and bioinformatics.
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Potential Role of Musashi-2 RNA-Binding Protein in Cancer EMT.
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pp32r1 controls the decay of the RNA-binding protein HuR.
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Preclinical and clinical efficacy of XPO1/CRM1 inhibition by the karyopherin inhibitor KPT-330 in Ph+ leukemias.
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Prediction of RBP binding sites on circRNAs using an LSTM-based deep sequence learning architecture.
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Prognostic alternative splicing regulatory network of RBM25 in hepatocellular carcinoma.
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Prognostic role and biologic features of Musashi-2 expression in colon polyps and during colorectal cancer progression.
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Prognostic value of Musashi-1 in endometrioid adenocarcinoma.
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Programmed cell death 4 protein (Pdcd4) and homeodomain-interacting protein kinase 2 (Hipk2) antagonistically control translation of Hipk2 mRNA.
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Prolyl isomerase Pin1 in cancer.
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Protein arginine methylation of SERBP1 by protein arginine methyltransferase 1 affects cytoplasmic/nuclear distribution.
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Proteomics-Based Characterization of miR-574-5p Decoy to CUGBP1 Suggests Specificity for mPGES-1 Regulation in Human Lung Cancer Cells.
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PTBP1 modulates osteosarcoma chemoresistance to cisplatin by regulating the expression of the copper transporter SLC31A1.
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PUM1 represses CDKN1B translation and contributes to prostate cancer progression.
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QKI deficiency leads to osteoporosis by promoting RANKL-induced osteoclastogenesis and disrupting bone metabolism.
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QKI, a miR-200 target gene, suppresses epithelial-to-mesenchymal transition and tumor growth.
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QKI-5 suppresses cyclin D1 expression and proliferation of oral squamous cell carcinoma cells via MAPK signalling pathway.
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QKI5-mediated alternative splicing of the histone variant macroH2A1 regulates gastric carcinogenesis.
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Quaking and miR-155 interactions in inflammation and leukemogenesis.
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Quaking orchestrates a post-transcriptional regulatory network of endothelial cell cycle progression critical to angiogenesis and metastasis.
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RBM10, a New Regulator of p53.
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RBM5 as a putative tumor suppressor gene for lung cancer.
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Re: Yves Allorya, Willemien Beukers, Ana Sagrera, et al. Telomerase Reverse Transcriptase Promoter Mutations in Bladder Cancer: High Frequency Across Stages, Detection in Urine, and Lack of Association with Outcome. Eur Urol 2014;65:360-6: Telomerase Expression and Stem Cells: Urologic Epithelial Perspective.
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Reaction of biological thiols with the tumor inhibitor jatrophone. Inhibition of RNA polymerase.
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Regulation of C-X-C chemokine gene expression by keratin 17 and hnRNP K in skin tumor keratinocytes.
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Regulation of ELL2 stability and polyubiquitination by EAF2 in prostate cancer cells.
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Regulation of gene expression by the RNA-binding protein Sam68 in cancer.
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Regulation of transcription by DNA-bound non-histone nuclear proteins.
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Regulators and mediators of radiation-induced fibrosis: Gene expression profiles and a rationale for Smad3 inhibition.
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Replicase-based plasmid DNA shows anti-tumor activity.
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Repression of caspase-3 and RNA-binding protein HuR cleavage by cyclooxygenase-2 promotes drug resistance in oral squamous cell carcinoma.
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Requirement of the mTOR kinase for the regulation of Maf1 phosphorylation and control of RNA polymerase III-dependent transcription in cancer cells.
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Reverse transcriptase of RNA tumor viruses. V. In vitro proteolysis of reverse transcriptase from avian myeloblastosis virus and isolation of a polypeptide manifesting only RNase H activity.
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RNA binding protein HuR regulates extracellular matrix gene expression and pH homeostasis independent of controlling HIF-1? signaling in nucleus pulposus cells.
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RNA polymerase - an important molecular target of triptolide in cancer cells.
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RNA polymerase activity in homotransplanted rat brain tumors initially induced by ethylnitrosourea.
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RNA polymerase chain reaction detects different levels of four alternatively spliced WT1 transcripts in Wilms' tumors.
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RNA Polymerase III Output Is Functionally Linked to tRNA Dimethyl-G26 Modification.
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RNA tumor virus and reverse transcriptase. I. Biochemical studies on the ESP-1 particles. II. Role of the reverse transcriptase in murine RNA tumor virus.
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RNA-binding protein (RBFOX1) inherited polymorphism rs8051518 is not associated with splice factor mutations in myelodysplastic syndromes and myeloproliferative neoplasms.
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RNA-binding protein 39: a promising therapeutic target for cancer.
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RNA-binding protein CELF1 enhances cell migration, invasion, and chemoresistance by targeting ETS2 in colorectal cancer.
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RNA-binding protein CELF1 promotes tumor growth and alters gene expression in oral squamous cell carcinoma.
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RNA-binding protein CELF6 is cell cycle regulated and controls cancer cell proliferation by stabilizing p21.
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RNA-binding protein Dnd1 inhibits epithelial-mesenchymal transition and cancer stem cell-related traits on hepatocellular carcinoma cells.
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RNA-binding protein HuR promotes bladder cancer progression by competitively binding to the long noncoding HOTAIR with miR-1.
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RNA-Binding Protein HuR Regulates Both Mutant and Wild-Type IDH1 in IDH1-Mutated Cancer.
Neoplasms
RNA-binding protein HuR sequesters microRNA-21 to prevent translation repression of proinflammatory tumor suppressor gene programmed cell death 4.
Neoplasms
RNA-binding protein IMP-3 promotes cell survival via IGF-II signaling after ionizing radiation.
Neoplasms
RNA-binding protein insulin-like growth factor II mRNA-binding protein 3 expression promotes tumor invasion and predicts early recurrence and poor prognosis in hepatocellular carcinoma.
Neoplasms
RNA-binding protein KHSRP promotes tumor growth and metastasis in non-small cell lung cancer.
Neoplasms
RNA-Binding Protein L1TD1 Interacts with LIN28 via RNA and is Required for Human Embryonic Stem Cell Self-Renewal and Cancer Cell Proliferation.
Neoplasms
RNA-Binding Protein La Mediates TGF?-Induced Epithelial to Mesenchymal Transition and Cancer Stem Cell Properties.
Neoplasms
RNA-binding protein Lin28 in cancer and immunity.
Neoplasms
RNA-binding protein LIN28 is a marker for primary extragonadal germ cell tumors: an immunohistochemical study of 131 cases.
Neoplasms
RNA-binding protein LIN28 is a marker for testicular germ cell tumors.
Neoplasms
RNA-binding protein LIN28 is a sensitive marker of ovarian primitive germ cell tumours.
Neoplasms
RNA-binding protein LIN28 is a sensitive marker of pediatric yolk sac tumors.
Neoplasms
RNA-binding protein MSI2 isoforms expression and regulation in progression of triple-negative breast cancer.
Neoplasms
RNA-Binding Protein Musashi1 Is a Central Regulator of Adhesion Pathways in Glioblastoma.
Neoplasms
RNA-binding protein NONO contributes to cancer cell growth and confers drug resistance as a theranostic target in TNBC.
Neoplasms
RNA-binding protein QKI regulates contact inhibition via Yes-associate protein in ccRCC.
Neoplasms
RNA-binding protein QKI suppresses breast cancer via RASA1/MAPK signaling pathway.
Neoplasms
RNA-binding protein RBM38 acts as a tumor suppressor in gastric cancer.
Neoplasms
RNA-binding protein RBM6 acts as a tumor suppressor gene to inhibit the progression of hepatocellular carcinoma.
Neoplasms
RNA-binding protein RBM6 as a tumor suppressor gene represses the growth and progression in laryngocarcinoma.
Neoplasms
RNA-binding protein RNPC1: acting as a tumor suppressor in breast cancer.
Neoplasms
RNA-binding protein SAMD4A inhibits breast tumor angiogenesis by modulating the balance of angiogenesis program.
Neoplasms
RNA-binding protein ZFP36/TTP protects against ferroptosis by regulating autophagy signaling pathway in hepatic stellate cells.
Neoplasms
RNA-Binding Protein ZFP36L1 Suppresses Hypoxia and Cell-Cycle Signaling.
Neoplasms
RNA-binding Protein, GADD45-alpha, p27(Kip1), p53 and Genotoxic Stress Response in Relation to Chemoresistance in Cancer.
Neoplasms
RNA-dependent RNA polymerase, RdRP, a promising therapeutic target for cancer and potentially COVID-19.
Neoplasms
Role of MicroRNA Let-7 in Modulating Multifactorial Aspect of Neurodegenerative Diseases: an Overview.
Neoplasms
Role of protein-protein interactions in the antiapoptotic function of EWS-Fli-1.
Neoplasms
Role of RNA-binding protein tristetraprolin in tumor necrosis factor-? mediated gene expression.
Neoplasms
Role of the RNA-binding protein HuR in colon carcinogenesis.
Neoplasms
Role of the RNA-binding protein La in cancer pathobiology.
Neoplasms
Rotavirus-encoded nonstructural protein 1 modulates cellular apoptotic machinery by targeting tumor suppressor protein p53.
Neoplasms
Rox8 promotes microRNA-dependent yki messenger RNA decay.
Neoplasms
S1-1 nuclear domains: characterization and dynamics as a function of transcriptional activity.
Neoplasms
Sam68 is Overexpressed in Epithelial Ovarian Cancer and Promotes Tumor Cell Proliferation.
Neoplasms
Sam68 promotes aerobic glycolysis in colorectal cancer by regulating PKM2 alternative splicing.
Neoplasms
Sam68 regulates translation of target mRNAs in male germ cells, necessary for mouse spermatogenesis.
Neoplasms
Semi-quantitative Detection of RNA-dependent RNA Polymerase Activity of Human Telomerase Reverse Transcriptase Protein.
Neoplasms
Serological and viral genetic features of patients with COVID-19 in a selected German patient cohort-correlation with disease characteristics.
Neoplasms
Several regions of p53 are involved in repression of RNA polymerase III transcription.
Neoplasms
Simian virus 40 large tumor antigen: a "RNA binding protein"?
Neoplasms
Small molecule enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2-mediated microRNA processing.
Neoplasms
Small Proline-Rich Protein 2A and 2D Are Regulated by the RBM38-p73 Axis and Associated with p73-Dependent Suppression of Chronic Inflammation.
Neoplasms
Specific anti-gastric cancer effects of a recombinant plasmid expressing nonstructural protein 1 of parvovirus H1.
Neoplasms
Specificity protein 1-dependent p53-mediated suppression of human manganese superoxide dismutase gene expression.
Neoplasms
SRSF7 maintains its homeostasis through the expression of Split-ORFs and nuclear body assembly.
Neoplasms
STAR RNA-binding protein Quaking suppresses cancer via stabilization of specific miRNA.
Neoplasms
Stimulation of Oct-4 activity by Ewing's sarcoma protein.
Neoplasms
Stress-response protein RBM3 attenuates the stem-like properties of prostate cancer cells by interfering with CD44 variant splicing.
Neoplasms
Structural basis of RNA polymerase III transcription initiation.
Neoplasms
Structure-Function Based Molecular Relationships in Ewing's Sarcoma.
Neoplasms
Study of the loosely bound non-histone chromatin proteins. Stimulation of deoxyribonucleic acid-templated ribonucleic acid synthesis by a specific deoxyribonucleic acid-binding phosphoprotein fraction.
Neoplasms
Sturcture-activity relationship of daunorubicin and its peptide derivatives.
Neoplasms
SUMOylation modulates the LIN28A-let-7 signaling pathway in response to cellular stresses in cancer cells.
Neoplasms
Suppressed humoral immunity is associated with dengue nonstructural protein NS1-elicited anti-death receptor antibody fractions in mice.
Neoplasms
Suppression of PTBP1 signaling is responsible for mesenchymal stem cell induced invasion of low malignancy cancer cells.
Neoplasms
Suramin inhibits tumor cell cytotoxicity mediated through natural killer cells, lymphokine-activated killer cells, monocytes, and tumor necrosis factor.
Neoplasms
Synthesis and pharmacological studies of some (1,4)-naphthoquinono[3,2-c]-1H-pyrazoles, 2-substituted amino-1,4-naphthoquinones, and related compounds.
Neoplasms
Synthesis of naphthalimide derivatives with potential anticancer activity, their comparative ds- and G-quadruplex-DNA binding studies and related biological activities.
Neoplasms
Tamoxifen represses alcohol-induced transcription of RNA polymerase III-dependent genes in breast cancer cells.
Neoplasms
TARBP2-mediated destabilization of Nanog overcomes sorafenib resistance in hepatocellular carcinoma.
Neoplasms
Targeted proteomics driven verification of biomarker candidates associated with breast cancer aggressiveness.
Neoplasms
Targeting RNA polymerase I with an oral small molecule CX-5461 inhibits ribosomal RNA synthesis and solid tumor growth.
Neoplasms
Targeting the interaction between RNA-binding protein HuR and FOXQ1 suppresses breast cancer invasion and metastasis.
Neoplasms
Telomerase and Telomere Length in Pulmonary Fibrosis.
Neoplasms
Telomerase reverse transcriptase moonlights: Therapeutic targets beyond telomerase.
Neoplasms
The Aberrant Expression of MicroRNA-125a-5p/IGF2BP3 Axis in Advanced Gastric Cancer and Its Clinical Relevance.
Neoplasms
The clinical importance of a transcription reverse-transcription concerted (TRC) diagnosis using peritoneal lavage fluids in gastric cancer with clinical serosal invasion: a prospective, multicenter study.
Neoplasms
The Expression of Insulin-Like Growth Factor 2 Messenger RNA-Binding Protein 3 in Langerhans Cell Histiocytosis and Langerhans Cell Sarcoma.
Neoplasms
The function of the RNA-binding protein hnRNP in cancer metastasis.
Neoplasms
The HRPT2 tumor suppressor gene product parafibromin associates with human PAF1 and RNA polymerase II.
Neoplasms
The HuR CMLD-2 inhibitor exhibits antitumor effects via MAD2 downregulation in thyroid cancer cells.
Neoplasms
The initiator methionine tRNA drives cell migration and invasion leading to increased metastatic potential in melanoma.
Neoplasms
The interaction of lncRNA EZR-AS1 with SMYD3 maintains overexpression of EZR in ESCC cells.
Neoplasms
The JNKs differentially regulate RNA polymerase III transcription by coordinately modulating the expression of all TFIIIB subunits.
Neoplasms
The non-reverse transcriptase activity of the human telomerase reverse transcriptase promotes tumor progression (review).
Neoplasms
The Oncofetal Protein IMP3: A Novel Molecular Marker to Predict Aggressive Meningioma.
Neoplasms
The oncofetal RNA-binding protein IGF2BP1 is a druggable, post-transcriptional super-enhancer of E2F-driven gene expression in cancer.
Neoplasms
The oncogenic RNA-binding protein Musashi1 is regulated by tumor suppressor miRNAs.
Neoplasms
The parafibromin tumor suppressor protein is part of a human Paf1 complex.
Neoplasms
The Prognostic Value of Epithelial Membrane Protein 1 (EMP-1) in Patients with Laryngeal Carcinoma.
Neoplasms
The Rbm38-p63 feedback loop is critical for tumor suppression and longevity.
Neoplasms
The RNA polymerase III repressor MAF1 is regulated by ubiquitin-dependent proteasome degradation and modulates cancer drug resistance and apoptosis.
Neoplasms
The RNA-binding protein AKAP8 suppresses tumor metastasis by antagonizing EMT-associated alternative splicing.
Neoplasms
The RNA-binding protein CUG-BP1 increases survivin expression in oesophageal cancer cells through enhanced mRNA stability.
Neoplasms
The RNA-binding protein CUGBP1 regulates stability of tumor necrosis factor mRNA in muscle cells: implications for myotonic dystrophy.
Neoplasms
The RNA-binding protein DDX1 promotes primary microRNA maturation and inhibits ovarian tumor progression.
Neoplasms
The RNA-binding protein DND1 acts sequentially as a negative regulator of pluripotency and a positive regulator of epigenetic modifiers required for germ cell reprogramming.
Neoplasms
The RNA-binding protein ESRP1 promotes human colorectal cancer progression.
Neoplasms
The RNA-binding protein hnRNPA2 regulates ?-catenin protein expression and is overexpressed in prostate cancer.
Neoplasms
The RNA-Binding Protein HuR in Digestive System Tumors.
Neoplasms
The RNA-binding protein HuR inhibits expression of CCL5 and limits recruitment of macrophages into tumors.
Neoplasms
The RNA-binding protein LARP4 regulates cancer cell migration and invasion.
Neoplasms
The RNA-binding protein MEX3B mediates resistance to cancer immunotherapy by downregulating HLA-A expression.
Neoplasms
The RNA-Binding Protein PCBP1 Functions as a Tumor Suppressor in Prostate Cancer by Inhibiting Mitogen Activated Protein Kinase 1.
Neoplasms
The RNA-binding protein Sam68 is a multifunctional player in human cancer.
Neoplasms
The RNA-binding protein Sam68 regulates tumor cell viability and hepatic carcinogenesis by inhibiting the transcriptional activity of FOXOs.
Neoplasms
The RNA-binding protein SERBP1 functions as a novel oncogenic factor in glioblastoma by bridging cancer metabolism and epigenetic regulation.
Neoplasms
The RNA-binding protein SORBS2 suppresses hepatocellular carcinoma tumourigenesis and metastasis by stabilizing RORA mRNA.
Neoplasms
The role of RNA-binding protein tristetraprolin in cancer and immunity.
Neoplasms
The roles of hnRNP A2/B1 in RNA biology and disease.
Neoplasms
The stability and oncogenic function of LIN28A are regulated by USP28.
Neoplasms
The Staufen1-dependent cell cycle regulon or how a misregulated RNA-binding protein leads to cancer.
Neoplasms
The stem cell-specific protein TRIM71 inhibits maturation and activity of the pro-differentiation miRNA let-7 via two independent molecular mechanisms.
Neoplasms
The superoxide dismutase 1 3'UTR maintains high expression of the SOD1 gene in cancer cells: The involvement of the RNA-binding protein AUF-1.
Neoplasms
The three Type 2A protein phosphatases, PP2Ac, PP4c and PP6c, are differentially regulated by Alpha4.
Neoplasms
The Toll like receptor 4 ligand cold-inducible RNA-binding protein as vaccination platform against cancer.
Neoplasms
The tumor suppressing effects of QKI-5 in prostate cancer: a novel diagnostic and prognostic protein.
Neoplasms
The tumor suppressor parafibromin is required for posttranscriptional processing of histone mRNA.
Neoplasms
The tumor suppressor, parafibromin, mediates histone H3 K9 methylation for cyclin D1 repression.
Neoplasms
The tumour suppressor brain tumour (Brat) regulates linker histone dBigH1 expression in the Drosophila female germline and the early embryo.
Neoplasms
Therapeutic targeting of circ-CUX1/EWSR1/MAZ axis inhibits glycolysis and neuroblastoma progression.
Neoplasms
Toll-like receptor 4 mediates synergism between alcohol and HCV in hepatic oncogenesis involving stem cell marker Nanog.
Neoplasms
Topoisomerase II? promotes activation of RNA polymerase I transcription by facilitating pre-initiation complex formation.
Neoplasms
Transcription factor TAFII250 phosphorylates the acidic domain of Mdm2 through recruitment of protein kinase CK2.
Neoplasms
Transcriptional repression of Myc underlies the tumour suppressor function of AGO1 in Drosophila.
Neoplasms
Transcriptionally active RNA polymerases from Morris hepatomas and rat liver. Elucidation of the mechanism for the preferential increase in the tumour RNA polymerase I.
Neoplasms
Transcriptome-wide analysis uncovers the targets of the RNA-binding protein MSI2 and effects of MSI2's RNA-binding activity on IL-6 signaling.
Neoplasms
Transcriptome-wide profiles of circular RNA and RNA-binding protein interactions reveal effects on circular RNA biogenesis and cancer pathway expression.
Neoplasms
Transcriptomic studies provide insights into the tumor suppressive role of miR-146a-5p in non-small cell lung cancer (NSCLC) cells.
Neoplasms
Transgenic overexpression of the oncofetal RNA binding protein KOC leads to remodeling of the exocrine pancreas.
Neoplasms
Translational Control of TOP2A Influences Doxorubicin Efficacy.
Neoplasms
Trisubstituted Pyrrolinones as Small-Molecule Inhibitors Disrupting the Protein-RNA Interaction of LIN28 and Let-7.
Neoplasms
Tumor necrosis factor and transforming growth factor ? regulate clock genes by controlling the expression of the cold inducible RNA-binding protein (CIRBP).
Neoplasms
Tumor Suppressing Properties of Rodent Parvovirus NS1 Proteins and Their Derivatives.
Neoplasms
Tumor suppressor RBM24 inhibits nuclear translocation of CTNNB1 and TP63 expression in liver cancer cells.
Neoplasms
Tumor-targeted Nanoparticle Delivery of HuR siRNA Inhibits Lung Tumor Growth In Vitro and In Vivo By Disrupting the Oncogenic Activity of the RNA-binding Protein HuR.
Neoplasms
UHM-ULM interactions in the RBM39-U2AF65 splicing-factor complex.
Neoplasms
Uncovering the role of hnRNP K, an RNA-binding protein, in B-cell lymphomas.
Neoplasms
Up-regulated expression of the MAT-8 gene in prostate cancer and its siRNA-mediated inhibition of expression induces a decrease in proliferation of human prostate carcinoma cells.
Neoplasms
Utility of immobilon-bound phosphoproteins as substrates for protein phosphatases from neutrophils.
Neoplasms
von Hippel-Lindau tumor suppressor gene-dependent mRNA stabilization of the survival factor parathyroid hormone-related protein in human renal cell carcinoma by the RNA-binding protein HuR.
Neoplasms
WT1 and kidney progenitor cells.
Neoplasms
ZFP36 Binds With PRC1 to Inhibit Tumor Growth and Increase 5-Fu Chemosensitivity of Hepatocellular Carcinoma.
Neoplasms
Zika Virus as Oncolytic Therapy for Brain Cancer: Myth or Reality?
Neoplasms
Zinc finger RNA-binding protein promotes non-small-cell carcinoma growth and tumor metastasis by targeting the Notch signaling pathway.
Neoplasms
Zmat3 Is a Key Splicing Regulator in the p53 Tumor Suppression Program.
Neoplasms
[Detection of tumor load in chronic myeloid leukemia during treatment with transplantation by conventional cytogenetics, nested-RT-PCR and FISH]
Neoplasms
[Primary neuroectodermal tumor (PNET) of the kidney: 26 cases. Current status of its diagnosis and treatment]
Neoplasms
[RNA-dependent RNA polymerase in tumor cells]
Neoplasms, Germ Cell and Embryonal
DND1 maintains germline stem cells via recruitment of the CCR4-NOT complex to target mRNAs.
Neoplasms, Germ Cell and Embryonal
LIN28 Is Selectively Expressed by Primordial and Pre-Meiotic Germ Cells in the Human Fetal Ovary.
Neoplasms, Germ Cell and Embryonal
RNA-binding protein LIN28 is a marker for primary extragonadal germ cell tumors: an immunohistochemical study of 131 cases.
Neoplasms, Germ Cell and Embryonal
RNA-binding protein LIN28 is a marker for testicular germ cell tumors.
Neoplasms, Germ Cell and Embryonal
RNA-binding protein LIN28 is a sensitive marker of ovarian primitive germ cell tumours.
Neoplasms, Neuroepithelial
Spinal cord astroblastoma with EWSR1-BEND2 fusion classified as HGNET-MN1 by methylation classification: a case report.
Neoplasms, Squamous Cell
L523S, an RNA-binding protein as a potential therapeutic target for lung cancer.
Nephritis
Inhibition of RNA-binding protein HuR reduces glomerulosclerosis in experimental nephritis.
Nervous System Diseases
A Live-Attenuated Zika Virus Vaccine with High Production Capacity Confers Effective Protection in Neonatal Mice.
Nervous System Diseases
CELF4 regulates translation and local abundance of a vast set of mRNAs, including genes associated with regulation of synaptic function.
Neuralgia
Intranasal delivery of an antisense oligonucleotide to the RNA-binding protein HuR relieves nerve injury-induced neuropathic pain.
Neuroblastoma
Activity of a 40 kDa RNA-binding protein correlates with MYCN and c-fos mRNA stability in human neuroblastoma.
Neuroblastoma
Antiapoptotic but not antiviral function of human bcl-2 assists establishment of Japanese encephalitis virus persistence in cultured cells.
Neuroblastoma
Application of Serum ELAVL4 (HuD) Antigen Assay for Small Cell Lung Cancer Diagnosis.
Neuroblastoma
Developmentally-regulated expression of mNapor encoding an apoptosis-induced ELAV-type RNA binding protein.
Neuroblastoma
Effect of low doses of actinomycin D on neuroblastoma cell lines.
Neuroblastoma
Genomic organization and isoform-specific tissue expression of human NAPOR (CUGBP2) as a candidate gene for familial arrhythmogenic right ventricular dysplasia.
Neuroblastoma
HuD, a neuronal-specific RNA-binding protein, is a potential regulator of MYCN expression in human neuroblastoma cells.
Neuroblastoma
Intratumoral anti-HuD immunotoxin therapy for small cell lung cancer and neuroblastoma.
Neuroblastoma
Isolation and expression of Napor/CUG-BP2 in embryo development.
Neuroblastoma
NDM29, a RNA polymerase III-dependent non coding RNA, promotes amyloidogenic processing of APP and amyloid ? secretion.
Neuroblastoma
Overexpression of tissue-nonspecific alkaline phosphatase increases the expression of neurogenic differentiation markers in the human SH-SY5Y neuroblastoma cell line.
Neuroblastoma
Post-transcriptional regulation of HSP70 expression following oxidative stress in SH-SY5Y cells: the potential involvement of the RNA-binding protein HuR.
Neuroblastoma
Region-specific alternative splicing in the nervous system: implications for regulation by the RNA-binding protein NAPOR.
Neuroblastoma
RNA-binding protein RBM3 prevents NO-induced apoptosis in human neuroblastoma cells by modulating p38 signaling and miR-143.
Neuroblastoma
The inhibition of 45A ncRNA expression reduces tumor formation, affecting tumor nodules compactness and metastatic potential in neuroblastoma cells.
Neurodegenerative Diseases
A conserved role for the ALS-linked splicing factor SFPQ in repression of pathogenic cryptic last exons.
Neurodegenerative Diseases
Abnormal TDP-43 function impairs activity-dependent BDNF secretion, synaptic plasticity, and cognitive behavior through altered Sortilin splicing.
Neurodegenerative Diseases
Activity-dependent FUS dysregulation disrupts synaptic homeostasis.
Neurodegenerative Diseases
ALS/FTLD-Linked Mutations in FUS Glycine Residues Cause Accelerated Gelation and Reduced Interactions with Wild-Type FUS.
Neurodegenerative Diseases
Amyloid-Forming Segment Induces Aggregation of FUS-LC Domain from Phase Separation Modulated by Site-Specific Phosphorylation.
Neurodegenerative Diseases
An Amyloid-Like Pathological Conformation of TDP-43 Is Stabilized by Hypercooperative Hydrogen Bonds.
Neurodegenerative Diseases
An optimized InCell Western screening technique identifies hexachlorophene as a novel potent TDP43 targeting drug.
Neurodegenerative Diseases
Ataxin-2 Is Droppin' Some Knowledge.
Neurodegenerative Diseases
Autophagy Stimulus Promotes Early HuR Protein Activation and p62/SQSTM1 Protein Synthesis in ARPE-19 Cells by Triggering Erk1/2, p38
Neurodegenerative Diseases
Biomolecular condensation of the microtubule-associated protein tau.
Neurodegenerative Diseases
Conserved role for Ataxin-2 in mediating endoplasmic reticulum dynamics.
Neurodegenerative Diseases
Cytoplasmic sequestration of FUS/TLS associated with ALS alters histone marks through loss of nuclear protein arginine methyltransferase 1.
Neurodegenerative Diseases
DCTN1 Binds to TDP-43 and Regulates TDP-43 Aggregation.
Neurodegenerative Diseases
Depletion of TDP-43 decreases fibril and plaque ?-amyloid and exacerbates neurodegeneration in an Alzheimer's mouse model.
Neurodegenerative Diseases
Detection of TAR DNA-binding protein 43 (TDP-43) oligomers as initial intermediate species during aggregate formation.
Neurodegenerative Diseases
Differential toxicity of TAR DNA-binding protein 43 isoforms depends on their submitochondrial localization in neuronal cells.
Neurodegenerative Diseases
Dysfunctional RNA-binding protein biology and neurodegeneration in experimental autoimmune encephalomyelitis in female mice.
Neurodegenerative Diseases
Elevated FUS/TLS expression is negatively associated with E-cadherin expression and prognosis of patients with non-small cell lung cancer.
Neurodegenerative Diseases
Exploring the Interaction of
Neurodegenerative Diseases
Frontotemporal dementia and amyotrophic lateral sclerosis-associated disease protein TDP-43 promotes dendritic branching.
Neurodegenerative Diseases
FUS ALS-causative mutations impair FUS autoregulation and splicing factor networks through intron retention.
Neurodegenerative Diseases
FUS binds the CTD of RNA polymerase II and regulates its phosphorylation at Ser2.
Neurodegenerative Diseases
FUS is sequestered in nuclear aggregates in ALS patient fibroblasts.
Neurodegenerative Diseases
FUS Regulates Activity of MicroRNA-Mediated Gene Silencing.
Neurodegenerative Diseases
Genetic Perturbation of TIA1 Reveals a Physiological Role in Fear Memory.
Neurodegenerative Diseases
HuD regulates SOD1 expression during oxidative stress in differentiated neuroblastoma cells and sporadic ALS motor cortex.
Neurodegenerative Diseases
Loss of Tdp-43 disrupts the axonal transcriptome of motoneurons accompanied by impaired axonal translation and mitochondria function.
Neurodegenerative Diseases
Mapping the Transcriptome-Wide Landscape of RBP Binding Sites Using gPAR-CLIP-seq: Bioinformatic Analysis.
Neurodegenerative Diseases
Mechanisms of TDP-43 Proteinopathy Onset and Propagation.
Neurodegenerative Diseases
Mislocalisation of TDP-43 to the cytoplasm causes cortical hyperexcitability and reduced excitatory neurotransmission in the motor cortex.
Neurodegenerative Diseases
Molecular Dissection of FUS Points at Synergistic Effect of Low-Complexity Domains in Toxicity.
Neurodegenerative Diseases
Molecular structure and interactions within amyloid-like fibrils formed by a low-complexity protein sequence from FUS.
Neurodegenerative Diseases
Motor neuron expression of the voltage-gated calcium channel cacophony restores locomotion defects in a Drosophila, TDP-43 loss of function model of ALS.
Neurodegenerative Diseases
Multistep process of FUS aggregation in the cell cytoplasm involves RNA-dependent and RNA-independent mechanisms.
Neurodegenerative Diseases
Neurotoxic effects of TDP-43 overexpression in C. elegans.
Neurodegenerative Diseases
Pleiotropic requirements for human TDP-43 in the regulation of cell and organelle homeostasis.
Neurodegenerative Diseases
PRO-MINE: A Bioinformatics Repository and Analytical Tool for TARDBP Mutations.
Neurodegenerative Diseases
PTBP1 and PTBP2 Repress Nonconserved Cryptic Exons.
Neurodegenerative Diseases
Residue-by-Residue View of In Vitro FUS Granules that Bind the C-Terminal Domain of RNA Polymerase II.
Neurodegenerative Diseases
Restoration of motor defects caused by loss of Drosophila TDP-43 by expression of the voltage-gated calcium channel, Cacophony, in central neurons.
Neurodegenerative Diseases
RNA-binding proteins in neurodegeneration: mechanisms in aggregate.
Neurodegenerative Diseases
Senataxin, defective in the neurodegenerative disorder ataxia with oculomotor apraxia 2, lies at the interface of transcription and the DNA damage response.
Neurodegenerative Diseases
Severe respiratory changes at end stage in a FUS-induced disease state in adult rats.
Neurodegenerative Diseases
Similar dose-dependence of motor neuron cell death caused by wild type human TDP-43 and mutants with ALS-associated amino acid substitutions.
Neurodegenerative Diseases
Six GU-rich (6GUR) FUS-binding motifs detected by normalization of CLIP-seq by Nascent-seq.
Neurodegenerative Diseases
Staufen 1 amplifies proapoptotic activation of the unfolded protein response.
Neurodegenerative Diseases
Structural basis for RNA recognition by the N-terminal tandem RRM domains of human RBM45.
Neurodegenerative Diseases
Structural Transition, Function and Dysfunction of TDP-43 in Neurodegenerative Diseases.
Neurodegenerative Diseases
TDP-43 dysfunction restricts dendritic complexity by inhibiting CREB activation and altering gene expression.
Neurodegenerative Diseases
TDP-43 enhances translation of specific mRNAs linked to neurodegenerative disease.
Neurodegenerative Diseases
TDP-43 prevents retrotransposon activation in the Drosophila motor system through regulation of Dicer-2 activity.
Neurodegenerative Diseases
TDP-43 regulates early-phase insulin secretion via CaV1.2-mediated exocytosis in islets.
Neurodegenerative Diseases
TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration.
Neurodegenerative Diseases
The cooperative binding of TDP-43 to GU-rich RNA repeats antagonizes TDP-43 aggregation.
Neurodegenerative Diseases
The Impact of ALS-Associated Genes hnRNPA1, MATR3, VCP and UBQLN2 on the Severity of TDP-43 Aggregation.
Neurodegenerative Diseases
The multi-functional RNA-binding protein G3BP1 and its potential implication in neurodegenerative disease.
Neurodegenerative Diseases
The Pathobiology of TDP-43 C-Terminal Fragments in ALS and FTLD.
Neurodegenerative Diseases
Tristetraprolin destabilizes NOX2 mRNA and protects dopaminergic neurons from oxidative damage in Parkinson's disease.
Neuroectodermal Tumors
A renal cell carcinoma with EWSR1-TFE3 fusion gene.
Neuroectodermal Tumors, Primitive
Methylcholanthrene induced murine primitive neuroectodermal tumor: ultrastructure and nuclear RNA polymerase activity.
Neuroectodermal Tumors, Primitive
Murine primitive neuroectodermal tumor: nucleolar isolation and RNA polymerase inhibition.
Neuroendocrine Tumors
Expression of glucose transporter-1 is correlated with hypoxia-inducible factor 1? and malignant potential in pancreatic neuroendocrine tumors.
Neuroendocrine Tumors
Reduced expression of the RNA-binding protein HuD in pancreatic neuroendocrine tumors correlates with low p27Kip1 levels and poor prognosis.
Neurofibrosarcoma
HuR/ELAVL1 drives malignant peripheral nerve sheath tumor growth and metastasis.
Neuroinflammatory Diseases
A novel target to reduce microglial inflammation and neuronal damage after deep hypothermic circulatory arrest.
Neuroinflammatory Diseases
Cold-inducible RNA-binding protein is an important mediator of alcohol-induced brain inflammation.
Neuroinflammatory Diseases
Cold-inducible RNA-binding protein mediates neuroinflammation in cerebral ischemia.
Neuroinflammatory Diseases
RNA-Binding Protein HuR Promotes Th17 Cell Differentiation and Can Be Targeted to Reduce Autoimmune Neuroinflammation.
Neuroinflammatory Diseases
Targeting Neurological Manifestations of Coronaviruses by Candidate Phytochemicals: A Mechanistic Approach.
Neuroinflammatory Diseases
Targeting the RNA-Binding Protein HuR Alleviates Neuroinflammation in Experimental Autoimmune Encephalomyelitis: Potential Therapy for Multiple Sclerosis.
Neuroinflammatory Diseases
The Potential Contribution of Dysfunctional RNA-Binding Proteins to the Pathogenesis of Neurodegeneration in Multiple Sclerosis and Relevant Models.
Neuroinflammatory Diseases
The RNA-binding protein HuR contributes to neuroinflammation by promoting C-C chemokine receptor 6 (CCR6) expression on Th17 cells.
Neuroinflammatory Diseases
The Value of Extracellular Cold-Inducible RNA-Binding Protein (eCIRP) in Predicting the Severity and Prognosis of Patients After Cardiac Arrest: A Preliminary Observational Study.
Neurologic Manifestations
Detection of human immunodeficiency virus type 2 in brain tissue.
Neuromuscular Diseases
Myo-granules Connect Physiology and Pathophysiology.
Neuromuscular Diseases
Systematic analysis of cis-elements in unstable mRNAs demonstrates that CUGBP1 is a key regulator of mRNA decay in muscle cells.
Neuromuscular Diseases
TDP-43 and RNA form amyloid-like myo-granules in regenerating muscle.
Newcastle Disease
Comparison of RNA polymerase associated with Newcastle disease virus and a temperature-sensitive mutant of Newcastle disease virus isolated from persistently infected L cells.
Newcastle Disease
Generation of recombinant lentogenic Newcastle disease virus from cDNA.
Newcastle Disease
Genomic Diversity and Evolution of Quasispecies in Newcastle Disease Virus Infections.
Newcastle Disease
Immunogenicity of a truncated enterovirus 71 VP1 protein fused to a Newcastle disease virus nucleocapsid protein fragment in mice.
Newcastle Disease
Immunogenicity of Newcastle disease virus vectors expressing Norwalk virus capsid protein in the presence or absence of VP2 protein.
Newcastle Disease
Mechanisms and consequences of Newcastle disease virus W protein subcellular localization in the nucleus or mitochondria.
Newcastle Disease
Methylation of messenger RNA of Newcastle disease virus in vitro by a virion-associated enzyme.
Newcastle Disease
Polyadenylation-dependent screening assay for respiratory syncytial virus RNA transcriptase activity and identification of an inhibitor.
Newcastle Disease
Presence of genomic polyadenylate and absence of detectable virion transcriptase in human coronavirus OC-43.
Newcastle Disease
Recombinant Newcastle Disease virus capsids displaying enterovirus 71 VP1 fragment induce a strong immune response in rabbits.
Newcastle Disease
Rescue of recombinant Newcastle disease virus: current cloning strategies and RNA polymerase provision systems.
Newcastle Disease
RNA-dependent RNA polymerase gene analysis of worldwide Newcastle disease virus isolates representing different virulence types and their phylogenetic relationship with other members of the paramyxoviridae.
Newcastle Disease
Studies on the structural basis of the RNA polymerase activity of newcastle disease virus particles.
Non-alcoholic Fatty Liver Disease
SIRT1 mediates the role of RNA-binding protein QKI 5 in the synthesis of triglycerides in non-alcoholic fatty liver disease mice via the PPAR?/FoxO1 signaling pathway.
Obesity
RNA-binding protein PTB and microRNA-221 coregulate AdipoR1 translation and adiponectin signaling.
Ocular Hypertension
Software for Quantifying and Batch Processing Images of Brn3a and RBPMS Immunolabelled Retinal Ganglion Cells in Retinal Wholemounts.
Oligodendroglioma
Somatostatin receptor 2A protein expression characterizes anaplastic oligodendrogliomas with favorable outcome.
Opsoclonus-Myoclonus Syndrome
High expression of neuro-oncological ventral antigen 1 correlates with poor prognosis in hepatocellular carcinoma.
Opsoclonus-Myoclonus Syndrome
Nova-1 regulates neuron-specific alternative splicing and is essential for neuronal viability.
Orthomyxoviridae Infections
A Naturally Occurring Deletion in the Effector Domain of H5N1 Swine Influenza Virus Nonstructural Protein 1 Regulates Viral Fitness and Host Innate Immunity.
Orthomyxoviridae Infections
Emerging antiviral drugs.
Orthomyxoviridae Infections
Reassortant Eurasian Avian-Like Influenza A(H1N1) Virus from a Severely Ill Child, Hunan Province, China, 2015.
Osteoarthritis
RNA-binding protein ZFP36L1 regulates osteoarthritis by modulating members of the heat shock protein 70 family.
Osteoarthritis, Knee
Synovial fluid concentrations of cold-inducible RNA-binding protein are associated with severity in knee osteoarthritis.
Osteoporosis
Case Report: Severe Osteoporosis and Preventive Therapy in RNA Polymerase III-Related Leukodystrophy.
Osteoporosis
Motor coordination defects in mice deficient for the Sam68 RNA-binding protein.
Osteosarcoma
Circular RNA LARP4 correlates with decreased Enneking stage, better histological response, and prolonged survival profiles, and it elevates chemosensitivity to cisplatin and doxorubicin via sponging microRNA-424 in osteosarcoma.
Osteosarcoma
Effects of mutation in hepatitis C virus nonstructural protein 5A on interferon resistance mediated by inhibition of PKR kinase activity in mammalian cells.
Osteosarcoma
Retargeting Polyomavirus-Like Particles to Cancer Cells by Chemical Modification of Capsid Surface.
Osteosarcoma
RNA-binding protein PUM2 suppresses osteosarcoma progression via partly and competitively binding to STARD13 3'UTR with miRNAs.
Osteosarcoma
The association of inhibitor of Growth 4 with its prognostic value in osteogenic sarcoma.
Ovarian Neoplasms
Expression, Intracellular Localization, and Prognostic Value of Plasminogen Activator Inhibitor 1 and PAI-1 RNA-Binding Protein 1 in Primary and Recurrent Ovarian Cancer: A Study of the Tumor Bank Ovarian Cancer Network.
Ovarian Neoplasms
High RBM3 expression in prostate cancer independently predicts a reduced risk of biochemical recurrence and disease progression.
Ovarian Neoplasms
Human La Protein: An RNA-Binding Protein Involved in Ovarian Cancer Development and Multidrug Resistance.
Ovarian Neoplasms
Inhibition of RNA-Binding Protein Musashi-1 Suppresses Malignant Properties and Reverses Paclitaxel Resistance in Ovarian Carcinoma.
Ovarian Neoplasms
lncRNA-PRLB Confers Paclitaxel Resistance of Ovarian Cancer Cells by Regulating RSF1/NF-?B Signaling Pathway.
Ovarian Neoplasms
miR-1224-5p inhibits the proliferation and invasion of ovarian cancer via targeting SND1.
Ovarian Neoplasms
Ovarian tumor cell detection in peripheral blood progenitor cells harvests by RT-PCR.
Ovarian Neoplasms
Regulation of hnRNPA1 by microRNAs controls the miR-18a-K-RAS axis in chemotherapy-resistant ovarian cancer.
Ovarian Neoplasms
RNA-binding protein LIN28B inhibits apoptosis through regulation of the AKT2/FOXO3A/BIM axis in ovarian cancer cells.
Ovarian Neoplasms
The RNA-Binding Protein CELF2 Inhibits Ovarian Cancer Progression by Stabilizing FAM198B.
Ovarian Neoplasms
The RNA-binding protein LARP1 is a post-transcriptional regulator of survival and tumorigenesis in ovarian cancer.
Ovarian Neoplasms
[Construction of TRAIL gene eukaryotic expression vector modulated by hTERT gene core promoter and its effect on apoptosis of ovarian cancer cells.]
Pancreatic Cyst
Bicc1 Polymerization Regulates the Localization and Silencing of Bound mRNA.
Pancreatic Neoplasms
An RNA-binding protein, Hu-antigen R, in pancreatic cancer epithelial to mesenchymal transition, metastasis, and cancer stem cells.
Pancreatic Neoplasms
Human RNA polymerase II-association factor 1 (hPaf1/PD2) regulates histone methylation and chromatin remodeling in pancreatic cancer.
Pancreatic Neoplasms
KIF20A-mediated RNA granule transport system promotes the invasiveness of pancreatic cancer cells.
Pancreatic Neoplasms
RNA-binding protein Musashi2 regulates Hippo signaling via SAV1 and MOB1 in pancreatic cancer.
Pancreatic Neoplasms
Use of IMP3 in identification of carcinoma in fine needle aspiration biopsies of pancreas.
pancreatic ribonuclease deficiency
Tiny abortive initiation transcripts exert antitermination activity on an RNA hairpin-dependent intrinsic terminator.
Pancreatitis
Extracellular cold-inducible RNA-binding protein regulates neutrophil extracellular trap formation and tissue damage in acute pancreatitis.
Pancreatitis
Increased admission serum cold-inducible RNA-binding protein concentration is associated with prognosis of severe acute pancreatitis.
Pancreatitis, Acute Necrotizing
Birnavirus VP1 proteins form a distinct subgroup of RNA-dependent RNA polymerases lacking a GDD motif.
Pancreatitis, Acute Necrotizing
Comparison of the RNA polymerase genes of marine birnavirus strains and other birnaviruses.
Pancreatitis, Acute Necrotizing
In vitro RNA synthesis by infectious pancreatic necrosis virus-associated RNA polymerase.
Pancreatitis, Acute Necrotizing
Incomplete dsRNA genomes in purified infectious pancreatic necrosis virus.
Pancreatitis, Acute Necrotizing
IPNV VP5, a novel anti-apoptosis gene of the Bcl-2 family, regulates Mcl-1 and viral protein expression.
Pancreatitis, Acute Necrotizing
Mapping the site of guanylylation on VP1, the protein primer for infectious pancreatic necrosis virus RNA synthesis.
Pancreatitis, Acute Necrotizing
Protein-primed RNA synthesis in vitro by the virion-associated RNA polymerase of infectious pancreatic necrosis virus.
Pancreatitis, Acute Necrotizing
Sequence analysis of infectious pancreatic necrosis virus genome segment B and its encoded VP1 protein: a putative RNA-dependent RNA polymerase lacking the Gly-Asp-Asp motif.
Pancreatitis, Acute Necrotizing
The N-terminus of the RNA polymerase from infectious pancreatic necrosis virus is the determinant of genome attachment.
Pancreatitis, Acute Necrotizing
VP3, a structural protein of infectious pancreatic necrosis virus, interacts with RNA-dependent RNA polymerase VP1 and with double-stranded RNA.
Papilloma
Emerging antiviral drugs.
Papilloma
Oral Papillomas Associated With Felis catus Papillomavirus Type 1 in 2 Domestic Cats.
Papilloma
The binding of RNA polymerase to polyoma and papilloma DNA.
Papilloma
Tumor regression is associated with a specific immune response to the E2 protein of cottontail rabbit papillomavirus.
Papillomavirus Infections
Approved Antiviral Drugs over the Past 50 Years.
Paralysis
Analysis of the RdRp, intergenic and structural polyprotein regions, and the complete genome sequence of Kashmir bee virus from infected honeybees (Apis mellifera) in Korea.
Paralysis
CsrA and TnaB Coregulate Tryptophanase Activity To Promote Exotoxin-Induced Killing of Caenorhabditis elegansby Enteropathogenic Escherichia coli.
Paralysis
Phylogenetic analysis of the RNA-Dependent RNA polymerase (RdRp) and a predicted structural protein (pSP) of the chronic bee paralysis virus (CBPV) isolated from various geographic regions.
Paralysis
Severe acute respiratory syndrome coronavirus protein nsp1 is a novel eukaryotic translation inhibitor that represses multiple steps of translation initiation.
Paralysis
The first complete genome sequence of an iflavirus from the endoparasitoid wasp Tetrastichus brontispae.
Paralysis
The use of RNA-dependent RNA polymerase for the taxonomic assignment of Picorna-like viruses (order Picornavirales) infecting Apis mellifera L. populations.
Paramyxoviridae Infections
Analysis of Paramyxovirus Transcription and Replication by High-Throughput Sequencing.
Paramyxoviridae Infections
Analysis of the mutations in the active site of the RNA-dependent RNA polymerase of human parainfluenza virus type 3 (HPIV3).
Paramyxoviridae Infections
Human parainfluenza virus type 2 L protein regions required for interaction with other viral proteins and mRNA capping.
Paramyxoviridae Infections
Human parainfluenza virus type 3 phosphoprotein: identification of serine 333 as the major site for PKC zeta phosphorylation.
Paramyxoviridae Infections
Identification of two essential aspartates for polymerase activity in parainfluenza virus L protein by a minireplicon system expressing secretory luciferase.
Paramyxoviridae Infections
Phosphoprotein, P of human parainfluenza virus type 3 prevents self-association of RNA-dependent RNA polymerase, L.
Paramyxoviridae Infections
Regions on the hemagglutinin-neuraminidase proteins of human parainfluenza virus type-1 and Sendai virus important for membrane fusion.
Paramyxoviridae Infections
RNA polymerase activity in virions of parainfluenza 1 virus (Sendai).
Paramyxoviridae Infections
Role of a highly conserved NH(2)-terminal domain of the human parainfluenza virus type 3 RNA polymerase.
Paramyxoviridae Infections
Specific interaction in vitro and in vivo of glyceraldehyde-3-phosphate dehydrogenase and LA protein with cis-acting RNAs of human parainfluenza virus type 3.
Paramyxoviridae Infections
Sumoylation of the P protein at K254 plays an important role in growth of parainfluenza virus 5 (PIV5).
Paramyxoviridae Infections
The switch between acute and persistent paramyxovirus infection caused by single amino acid substitutions in the RNA polymerase P subunit.
Paramyxoviridae Infections
Two regions of the P protein are required to be active with the L protein for human parainfluenza virus type 1 RNA polymerase activity.
Paraneoplastic Syndromes
ANOVA, a putative astrocytic RNA-binding protein gene that maps to chromosome 19q13.3.
Paraneoplastic Syndromes, Nervous System
Autoantibodies against the Hel-N1 RNA-binding protein among patients with lung carcinoma: an association with type I anti-neuronal nuclear antibodies.
Parathyroid Neoplasms
Loss of expression for the Wnt pathway components adenomatous polyposis coli and glycogen synthase kinase 3-beta in parathyroid carcinomas.
Parathyroid Neoplasms
The tumor suppressor, parafibromin, mediates histone H3 K9 methylation for cyclin D1 repression.
Parkinson Disease
Association between the neuron-specific RNA-binding protein ELAVL4 and Parkinson disease.
Parkinson Disease
Spen modulates lipid droplet content in adult Drosophila glial cells and protects against paraquat toxicity.
Parkinson Disease
Targeted Quantification of Detergent-Insoluble RNA-Binding Proteins in Human Brain Reveals Stage and Disease Specific Co-aggregation in Alzheimer's Disease.
Parkinson Disease
Tristetraprolin destabilizes NOX2 mRNA and protects dopaminergic neurons from oxidative damage in Parkinson's disease.
Parkinsonian Disorders
Ectopic expression of Musashi-1 in Alzheimer disease and Pick disease.
Parkinsonian Disorders
Investigating FUS variation in Parkinson's disease.
Parvoviridae Infections
A putative nucleoside triphosphate-binding domain in the nonstructural protein of B19 parvovirus is required for cytotoxicity.
Parvoviridae Infections
IgG response to the immunoreactive region of parvovirus B19 nonstructural protein by immunoblot assay with a recombinant antigen.
Parvoviridae Infections
Porcine Parvovirus Infection Causes Pig Placenta Tissue Damage Involving Nonstructural Protein 1 (NS1)-Induced Intrinsic ROS/Mitochondria-Mediated Apoptosis.
Pemphigoid, Bullous
Bullous pemphigoid sera that contain antibodies to BPAg2 also contain antibodies to LABD97 that recognize epitopes distal to the NC16A domain.
Pemphigoid, Bullous
Interaction of BP180 (type XVII collagen) and alpha6 integrin is necessary for stabilization of hemidesmosome structure.
Pemphigoid, Bullous
Serological studies in bullous pemphigoid: a literature review of antibody titers at presentation and in clinical remission.
Pemphigus
The CD40/CD40 ligand system is involved in the pathogenesis of pemphigus.
Periodontitis
Draft genome sequence of Fusobacterium nucleatum ChDC F128, isolated from a periodontitis lesion.
Periodontitis
The induced RNA-binding protein, HuR, targets 3'-UTR region of IL-6 mRNA and enhances its stabilization in periodontitis.
Persistent Infection
A Secreted Viral Nonstructural Protein Determines Intestinal Norovirus Pathogenesis.
Persistent Infection
Antigenic and genetic variation in cytopathic hepatitis A virus variants arising during persistent infection: evidence for genetic recombination.
Persistent Infection
Assembly of viroplasms by viral nonstructural protein Pns9 is essential for persistent infection of rice gall dwarf virus in its insect vector.
Persistent Infection
Borrelia burgdorferi erpT expression in the arthropod vector and murine host.
Persistent Infection
Coxsackievirus B3 replication and persistence in intestinal cells from mice infected orally and in the human CaCo-2 cell line.
Persistent Infection
Expression of the aphthovirus RNA polymerase gene in Escherichia coli and its use together with other bioengineered nonstructural antigens in detection of late persistent infections.
Persistent Infection
Insights into structural dynamics of allosteric binding sites in HCV RNA-dependent RNA polymerase.
Persistent Infection
Intrahost Selection Pressure Drives Equine Arteritis Virus Evolution during Persistent Infection in the Stallion Reproductive Tract.
Persistent Infection
Prevalence of antibodies to human parvovirus B19 nonstructural protein in persons with various clinical outcomes following B19 infection.
Persistent Infection
Restricted viral RNA synthesis in establishment of persistent infection in Vero cells with a Sendai virus mutant.
Persistent Infection
Systemic Expression of a Viral RdRP Protects Against Retrovirus Infection and Disease.
Phlebotomus Fever
Insights into the Evolutionary Origin of Mediterranean Sandfly Fever Viruses.
Picornaviridae Infections
Highlights in the development of new antiviral agents.
Pituitary Neoplasms
Expression of cold-inducible RNA-binding protein (CIRP) in pituitary adenoma and its relationships with tumor recurrence.
Plague
Evidence for the involvement of influenza A (fowl plague Rostock) virus protein P2 in ApG and mRNA primed in vitro RNA synthesis.
Plague
Evolutionary selection of biofilm-mediated extended phenotypes in Yersinia pestis in response to a fluctuating environment.
Plague
[Inhibitory effect of alpha-methyl-1-adamantane methylamine hydrochloride (rimantadine) on RNA-dependent RNA polymerase induction in culture of cells, infected with influenza virus]
Plasmacytoma
Transcription termination and chromatin structure of the active immunoglobulin kappa gene locus.
Pneumonia
Acetylcysteine for the Treatment of Suspected Remdesivir-Associated Acute Liver Failure in COVID-19: A Case Series.
Pneumonia
Cold-inducible RNA-binding protein might determine the severity and the presences of major/minor criteria for severe community-acquired pneumonia and best predicted mortality.
Pneumonia
Crystallization and preliminary X-ray diffraction studies of a surface mutant of the middle domain of PB2 from human influenza A (H1N1) virus.
Pneumonia
Molecular mechanisms of respiratory syncytial virus replication: a guide for the development of antivirals.
Pneumonia
Neutrophil extracellular traps induced by VP1 contribute to pulmonary edema during EV71 infection.
Pneumonia
Plant-derived exosomal microRNAs inhibit lung inflammation induced by exosomes SARS-CoV-2 Nsp12.
Poliomyelitis
Crystal structures of active and inactive conformations of a caliciviral RNA-dependent RNA polymerase.
Poliomyelitis
Nucleotide variation in Sabin type 3 poliovirus from an Albanian infant with agammaglobulinemia and vaccine associated poliomyelitis.
Poliomyelitis
Poliovirus RNA synthesis in vitro: structural elements and antibody inhibition.
Poliomyelitis
StralSV: assessment of sequence variability within similar 3D structures and application to polio RNA-dependent RNA polymerase.
Poliomyelitis
Studies on the attenuation phenotype of polio vaccines: poliovirus RNA polymerase derived from Sabin type 1 sequence is temperature sensitive in the uridylylation of VPg.
Polymyositis
Anti-synthetase syndrome: a new autoantibody to phenylalanyl transfer RNA synthetase (anti-Zo) associated with polymyositis and interstitial pneumonia.
Polymyositis
Coexistence of anti-Jo1 and anti-signal recognition particle antibodies in a polymyositis patient.
Polymyositis
The long-term outcome of interstitial lung disease with anti-aminoacyl-tRNA synthetase antibodies.
Porcine Reproductive and Respiratory Syndrome
A Nanobody Targeting Viral Nonstructural Protein 9 Inhibits Porcine Reproductive and Respiratory Syndrome Virus Replication.
Porcine Reproductive and Respiratory Syndrome
Amino acid at position 176 was essential for porcine reproductive and respiratory syndrome virus (PRRSV) non-structural protein 1? (nsp1?) as an inhibitor to the induction of IFN-?.
Porcine Reproductive and Respiratory Syndrome
Amino acid residues Ala283 and His421 in the RNA-dependent RNA polymerase of porcine reproductive and respiratory syndrome virus play important roles in viral ribavirin sensitivity and quasispecies diversity.
Porcine Reproductive and Respiratory Syndrome
B Cell Tetramer Development for Veterinary Vaccinology.
Porcine Reproductive and Respiratory Syndrome
Cellular poly(c) binding proteins 1 and 2 interact with porcine reproductive and respiratory syndrome virus nonstructural protein 1? and support viral replication.
Porcine Reproductive and Respiratory Syndrome
Characterization and utility of phages bearing peptides with affinity to porcine reproductive and respiratory syndrome virus nsp7 protein.
Porcine Reproductive and Respiratory Syndrome
Cold-inducible RNA-binding protein (CIRBP) promotes porcine reproductive and respiratory syndrome virus (PRRSV)-induced inflammatory response.
Porcine Reproductive and Respiratory Syndrome
Complex assembly, crystallization and preliminary X-ray crystallographic studies of the swine major histocompatibility complex molecule SLA-1*1502.
Porcine Reproductive and Respiratory Syndrome
Critical role of cytochrome c1 and its cleavage in porcine reproductive and respiratory syndrome virus nonstructural protein 4-induced cell apoptosis via interaction with nsp4.
Porcine Reproductive and Respiratory Syndrome
Development of Monoclonal Antibodies Specifically Recognizing the Nonstructural Protein 12 of Type 2 Porcine Reproductive and Respiratory Syndrome Virus.
Porcine Reproductive and Respiratory Syndrome
Differential host cell gene expression and regulation of cell cycle progression by nonstructural protein 11 of porcine reproductive and respiratory syndrome virus.
Porcine Reproductive and Respiratory Syndrome
Effective suppression of replication of porcine reproductive and respiratory syndrome virus by adenovirus-mediated small interfering RNAs targeting ORF1b, 5 and 7 genes.
Porcine Reproductive and Respiratory Syndrome
Efficient -2 frameshifting by mammalian ribosomes to synthesize an additional arterivirus protein.
Porcine Reproductive and Respiratory Syndrome
Galectin-3 inhibits replication of porcine reproductive and respiratory syndrome virus by interacting with viral Nsp12 in vitro.
Porcine Reproductive and Respiratory Syndrome
Identification of a novel linear B-cell epitope in nonstructural protein 11 of porcine reproductive and respiratory syndrome virus that are conserved in both genotypes.
Porcine Reproductive and Respiratory Syndrome
Identification of an Intramolecular Switch That Controls the Interaction of Helicase nsp10 with Membrane-Associated nsp12 of Porcine Reproductive and Respiratory Syndrome Virus.
Porcine Reproductive and Respiratory Syndrome
Identification of epitopes on nonstructural protein 7 of porcine reproductive and respiratory syndrome virus recognized by monoclonal antibodies using phage-display technology.
Porcine Reproductive and Respiratory Syndrome
Identification of Nonstructural Protein 8 as the N-Terminus of the RNA-Dependent RNA Polymerase of Porcine Reproductive and Respiratory Syndrome Virus.
Porcine Reproductive and Respiratory Syndrome
Identification of Porcine Reproductive and Respiratory Syndrome Virus ORF1a-Encoded Nonstructural Proteins in Virus-Infected Cells.
Porcine Reproductive and Respiratory Syndrome
Identification of the strain-specifically truncated nonstructural protein 10 of porcine reproductive and respiratory syndrome virus in infected cells.
Porcine Reproductive and Respiratory Syndrome
Identification of three site mutations in nonstructural protein 1?, glycoprotein 3 and glycoprotein 5 that correlate with increased interferon ? resistance of porcine reproductive and respiratory syndrome virus.
Porcine Reproductive and Respiratory Syndrome
Identification of two auto-cleavage products of nonstructural protein 1 (nsp1) in porcine reproductive and respiratory syndrome virus infected cells: nsp1 function as interferon antagonist.
Porcine Reproductive and Respiratory Syndrome
Interaction of cellular poly(C)-binding protein 2 with nonstructural protein 1? is beneficial to Chinese highly pathogenic porcine reproductive and respiratory syndrome virus replication.
Porcine Reproductive and Respiratory Syndrome
Interleukin-1? expression by a recombinant porcine reproductive and respiratory syndrome virus.
Porcine Reproductive and Respiratory Syndrome
Involvement of PRRSV NSP3 and NSP5 in the autophagy process.
Porcine Reproductive and Respiratory Syndrome
Mapping the nonstructural protein interaction network of porcine reproductive and respiratory syndrome virus.
Porcine Reproductive and Respiratory Syndrome
Mutagenesis analysis of porcine reproductive and respiratory syndrome virus nonstructural protein 7.
Porcine Reproductive and Respiratory Syndrome
Mutations in a Highly Conserved Motif of nsp1? Protein Attenuate the Innate Immune Suppression Function of Porcine Reproductive and Respiratory Syndrome Virus.
Porcine Reproductive and Respiratory Syndrome
Nonstructural protein 11 (nsp11) of porcine reproductive and respiratory syndrome virus (PRRSV) promotes PRRSV infection in MARC-145 cells.
Porcine Reproductive and Respiratory Syndrome
Nonstructural Protein 11 of Porcine Reproductive and Respiratory Syndrome Virus Suppresses Both MAVS and RIG-I Expression as One of the Mechanisms to Antagonize Type I Interferon Production.
Porcine Reproductive and Respiratory Syndrome
Nonstructural protein 1? subunit-based inhibition of NF-?B activation and suppression of interferon-? production by porcine reproductive and respiratory syndrome virus.
Porcine Reproductive and Respiratory Syndrome
Nonstructural protein 9 residues 586 and 592 are critical sites in determining the replication efficiency and fatal virulence of the Chinese highly pathogenic porcine reproductive and respiratory syndrome virus.
Porcine Reproductive and Respiratory Syndrome
Nuclear export signal of PRRSV NSP1? is necessary for type I IFN inhibition.
Porcine Reproductive and Respiratory Syndrome
ORF1a of highly pathogenic PRRS attenuated vaccine virus plays a key role in neutralizing antibody induction in piglets and virus neutralization in vitro.
Porcine Reproductive and Respiratory Syndrome
Porcine reproductive and respiratory syndrome virus expressing E2 of classical swine fever virus protects pigs from a lethal challenge of highly-pathogenic PRRSV and CSFV.
Porcine Reproductive and Respiratory Syndrome
Porcine Reproductive and Respiratory Syndrome Virus Infection Induces both eIF2? Phosphorylation-Dependent and -Independent Host Translation Shutoff.
Porcine Reproductive and Respiratory Syndrome
Porcine Reproductive and Respiratory Syndrome Virus Nonstructural Protein 1 Beta Interacts with Nucleoporin 62 To Promote Viral Replication and Immune Evasion.
Porcine Reproductive and Respiratory Syndrome
Porcine reproductive and respiratory syndrome virus nonstructural protein 1beta modulates host innate immune response by antagonizing IRF3 activation.
Porcine Reproductive and Respiratory Syndrome
Programmed -2/-1 Ribosomal Frameshifting in Simarteriviruses: an Evolutionarily Conserved Mechanism.
Porcine Reproductive and Respiratory Syndrome
Proteasomal degradation of nonstructural protein 12 by RNF114 suppresses porcine reproductive and respiratory syndrome virus replication.
Porcine Reproductive and Respiratory Syndrome
Proteolytic processing of the porcine reproductive and respiratory syndrome virus replicase.
Porcine Reproductive and Respiratory Syndrome
PRR5, 7 and 9 positively modulate TOR signaling-mediated root cell proliferation by repressing TANDEM ZINC FINGER 1 in Arabidopsis.
Porcine Reproductive and Respiratory Syndrome
Suppression of immune responses in pigs by nonstructural protein 1 of Porcine reproductive and respiratory syndrome virus.
Porcine Reproductive and Respiratory Syndrome
The DEAD-box RNA helicase 5 positively regulates the replication of porcine reproductive and respiratory syndrome virus by interacting with viral Nsp9 in vitro.
Porcine Reproductive and Respiratory Syndrome
The Endoribonuclease Activity Essential for the Nonstructural Protein 11 of Porcine Reproductive and Respiratory Syndrome Virus to Inhibit NLRP3 Inflammasome-Mediated IL-1? Induction.
Porcine Reproductive and Respiratory Syndrome
The interaction between host Annexin A2 and viral Nsp9 is beneficial for replication of porcine reproductive and respiratory syndrome virus.
Porcine Reproductive and Respiratory Syndrome
The interaction of nonstructural protein 9 with retinoblastoma protein benefits the replication of genotype 2 porcine reproductive and respiratory syndrome virus in vitro.
Porcine Reproductive and Respiratory Syndrome
The Nonstructural Protein 1 Papain-Like Cysteine Protease Was Necessary for Porcine Reproductive and Respiratory Syndrome Virus Nonstructural Protein 1 to Inhibit Interferon-? Induction.
Porcine Reproductive and Respiratory Syndrome
The nonstructural protein 11 of porcine reproductive and respiratory syndrome virus induces STAT2 degradation to inhibit interferon signaling.
Porcine Reproductive and Respiratory Syndrome
The nonstructural protein 11 of porcine reproductive and respiratory syndrome virus inhibits NF-?B signaling by means of its deubiquitinating activity.
Porcine Reproductive and Respiratory Syndrome
The Nsp12-coding region of type 2 PRRSV is required for viral subgenomic mRNA synthesis.
Porcine Reproductive and Respiratory Syndrome
The Nucleocapsid Protein and Nonstructural Protein 10 of Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus Enhance CD83 Production via NF-?B and Sp1 Signaling Pathways.
Poxviridae Infections
Emerging antiviral drugs.
Pre-Eclampsia
Lin28B/miR-92b Promote the Proliferation, Migration, and Invasion in the Pathogenesis of Preeclampsia via the DKK1/Wnt/?-Catenin Pathway.
Pre-Eclampsia
NRP1 and MMP9 are dual targets of RNA-binding protein QKI5 to alter VEGF-R/ NRP1 signalling in trophoblasts in preeclampsia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
CDX2 gene expression in acute lymphoblastic leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
ETV6/RUNX1 transcript is a target of RNA-binding protein IGF2BP1 in t(12;21)(p13;q22)-positive acute lymphoblastic leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
False-Positive Nonstructural Protein 1 Antigen in a Patient with Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia: A Case Report with Literature Review.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
The Role of Type I Insulin Like Growth Factor Receptor (IGF-IR) in Adult and Childhood Acute Lymphoblastic Leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
[Effect of CDK Inhibitor LS-007 on Acute Lymphoblastic Leukemia and Its Mechanism].
Prostatic Neoplasms
Alternative splicing of the cyclin D1 proto-oncogene is regulated by the RNA-binding protein Sam68.
Prostatic Neoplasms
Distinct roles for the RNA-binding protein Staufen1 in prostate cancer.
Prostatic Neoplasms
Dysregulation of spliceosome gene expression in advanced prostate cancer by RNA-binding protein PSF.
Prostatic Neoplasms
Genotoxic stress causes the accumulation of the splicing regulator Sam68 in nuclear foci of transcriptionally active chromatin.
Prostatic Neoplasms
Identification of RNA-binding protein SNRPA1 for prognosis in prostate cancer.
Prostatic Neoplasms
Insulin-like growth factor-I receptor is suppressed through transcriptional repression and mRNA destabilization by a novel energy restriction-mimetic agent.
Prostatic Neoplasms
Molecular staging of prostate cancer. II. A comparison of the application of an enhanced reverse transcriptase polymerase chain reaction assay for prostate specific antigen versus prostate specific membrane antigen.
Prostatic Neoplasms
Molecular staging of prostate cancer. III. Effects of cystoscopy and needle biopsy on the enhanced reverse transcriptase polymerase chain reaction assay.
Prostatic Neoplasms
Prostate tumor cells infected with a recombinant influenza virus expressing a truncated NS1 protein activate cytolytic CD8+ cells to recognize noninfected tumor cells.
Prostatic Neoplasms
RNA-binding protein Musashi2 stabilizing androgen receptor drives prostate cancer progression.
Prostatic Neoplasms
Stress-response protein RBM3 attenuates the stem-like properties of prostate cancer cells by interfering with CD44 variant splicing.
Prostatic Neoplasms
The landscape of RNA polymerase II-associated chromatin interactions in prostate cancer.
Prostatic Neoplasms
The RNA-binding and adaptor protein Sam68 modulates signal-dependent splicing and transcriptional activity of the androgen receptor.
Prostatic Neoplasms
The RNA-binding protein FXR1 modulates prostate cancer progression by regulating FBXO4.
Prostatic Neoplasms
The RNA-binding protein hnRNPA2 regulates ?-catenin protein expression and is overexpressed in prostate cancer.
Prostatic Neoplasms
The RNA-binding protein HuR opposes the repression of ERBB-2 gene expression by microRNA miR-331-3p in prostate cancer cells.
Prostatic Neoplasms
The RNA-Binding Protein PCBP1 Functions as a Tumor Suppressor in Prostate Cancer by Inhibiting Mitogen Activated Protein Kinase 1.
Prostatic Neoplasms
The RNA-binding protein Sam68 contributes to proliferation and survival of human prostate cancer cells.
Proteinuria
Proteinuria and angiotensin converting enzyme (ACE) gene polymorphism.
Proteinuria
Sub-chronic microcystin-LR renal toxicity in rats fed a high fat/high cholesterol diet.
Pseudorabies
A differential ELISA based on recombinant immunodominant epitopes of the gE gene of SHV-1 in a baculovirus-insect cell system to discriminate between pigs infected naturally with pseudorabies and vaccinated pigs.
Pseudorabies
Functional complementation of UL3.5-negative pseudorabies virus by the bovine herpesvirus 1 UL3.5 homolog.
Pseudorabies
In vitro stimulation of specific RNA polymerase II-mediated transcription by the pseudorabies virus immediate early protein.
Pseudorabies
Recombinant pseudorabies virus expressing P12A and 3C of FMDV can partially protect piglets against FMDV challenge.
Psoriasis
RT-PCR topography of chronic psoriasis skin based on analysis of T-cell receptor B variable region gene usage.
Psoriasis
Suprabasal overexpression of the hsRPB7 gene in psoriatic epidermis as identified by a reverse transcriptase-polymerase chain reaction differential display model comparing psoriasis plaque tissue with peritonsillar mucosa.
Pulmonary Fibrosis
Extracellular CIRP Induces an Inflammatory Phenotype in Pulmonary Fibroblasts via TLR4.
Pulmonary Fibrosis
Telomerase and Telomere Length in Pulmonary Fibrosis.
Rabies
A dual-functional priming-capping loop of rhabdoviral RNA polymerases directs terminal de novo initiation and capping intermediate formation.
Rabies
A Dynein Light Chain 1 Binding Motif in Rabies Virus Polymerase L Protein Plays a Role in Microtubule Reorganization and Viral Primary Transcription.
Rabies
An In Vitro RNA Synthesis Assay for Rabies Virus Defines Ribonucleoprotein Interactions Critical for Polymerase Activity.
Rabies
An RNA polymerase activity in purified rabies virions.
Rabies
Characterization of P gene-deficient rabies virus: propagation, pathogenicity and antigenicity.
Rabies
Identification of a rabies virus T cell epitope on the basis of its similarity with a hepatitis B surface antigen peptide presented to T cells by the same MHC molecule (HLA-DPw4).
Rabies
Identification of a region of the rabies virus N protein involved in direct binding to the viral RNA.
Rabies
In silico structural elucidation of the rabies RNA-dependent RNA polymerase (RdRp) toward the identification of potential rabies virus inhibitors.
Rabies
Mapping the interacting domains between the rabies virus polymerase and phosphoprotein.
Rabies
Molecular docking studies with rabies virus glycoprotein to design viral therapeutics.
Rabies
Molecular Function Analysis of Rabies Virus RNA Polymerase L Protein by Using an L Gene-Deficient Virus.
Rabies
Nucleocytoplasmic shuttling of the rabies virus P protein requires a nuclear localization signal and a CRM1-dependent nuclear export signal.
Rabies
Nucleotide and deduced amino acid sequences of the nominal nonstructural phosphoprotein of the ERA, PM and CVS-11 strains of rabies virus.
Rabies
Phosphorylation of the N and M1 proteins of rabies virus.
Rabies
Phylogenetic analysis of partial RNA-polymerase blocks II and III of Rabies virus isolated from the main rabies reservoirs in Brazil.
Rabies
Polymerase activity of in vitro mutated rabies virus L protein.
Rabies
Prokaryotic Expression, Purification, and Polyclonal Antibody Production of a Truncated Recombinant Rabies Virus L Protein.
Rabies
Rabies virus M protein expressed in Escherichia coli and its regulatory role in virion-associated transcriptase activity.
Rabies
Rabies virus P protein interacts with STAT1 and inhibits interferon signal transduction pathways.
Rabies
Rabies: Presentation, case management and therapy.
Rabies
Segmentation of the rabies virus genome.
Rabies
Signature motifs of GDP polyribonucleotidyltransferase, a non-segmented negative strand RNA viral mRNA capping enzyme, domain in the L protein are required for covalent enzyme-pRNA intermediate formation.
Rabies
Studies on rabies virus RNA polymerase: 1. cDNA cloning of the catalytic subunit (L protein) of avirulent HEP-flury strain and its expression in animal cells.
Rabies
Studies on the rabies virus RNA polymerase: 2. Possible relationships between the two forms of the non-catalytic subunit (P protein).
Rabies
Studies on the rabies virus RNA polymerase: 3. Two-dimensional electrophoretic analysis of the multiplicity of non-catalytic subunit (P protein).
Rabies
The Mechanism and Clinical Outcome of patients with Corona Virus Disease 2019 Whose Nucleic Acid Test has changed from negative to positive, and the therapeutic efficacy of Favipiravir: A structured summary of a study protocol for a randomised controlled trial.
Rabies
The specificity of rabies virus RNA encapsidation by nucleoprotein.
Rabies
Transcriptase activity associated with rabies virion.
Rabies
Vesicular Stomatitis Virus Phosphoprotein Dimerization Domain Is Dispensable for Virus Growth.
Rabies
[Characterization of RdRp gene of rabies virus in China]
Raynaud Disease
Integrated Diagnosis Project for Inflammatory Myopathies: An association between autoantibodies and muscle pathology.
Raynaud Disease
Sensitivity and specificity of anti-Jo-1 antibodies in autoimmune diseases with myositis.
Raynaud Disease
Skeletal Muscle Involvement in Antisynthetase Syndrome.
Raynaud Disease
[Antisynthetase myopathy].
Renal Insufficiency
Direct-acting antivirals for hepatitis C virus in patients on maintenance dialysis.
Renal Insufficiency, Chronic
Real-world safety and efficacy of sofosbuvir and ledipasvir for elderly patients.
Reoviridae Infections
Avian reovirus nonstructural protein microNS forms viroplasm-like inclusions and recruits protein sigmaNS to these structures.
Reoviridae Infections
Formation of the factory matrix is an important, though not a sufficient function of nonstructural protein mu NS during reovirus infection.
Reoviridae Infections
Protease cleavage of reovirus capsid protein mu1/mu1C is blocked by alkyl sulfate detergents, yielding a new type of infectious subvirion particle.
Reperfusion Injury
Blocking cold-inducible RNA-binding protein protects liver from ischemia-reperfusion injury.
Reperfusion Injury
Inhibition of a triggering receptor expressed on myeloid cells-1 (TREM-1) with an extracellular cold-inducible RNA-binding protein (eCIRP)-derived peptide protects mice from intestinal ischemia-reperfusion injury.
Reperfusion Injury
The Protective Effect of a Short Peptide Derived from Cold-Inducible Rna-Binding Protein in Renal Ischemia-Reperfusion Injury.
Respiratory Distress Syndrome
Deficiency in cold-inducible RNA-binding protein attenuates acute respiratory distress syndrome induced by intestinal ischemia-reperfusion.
Respiratory Insufficiency
A de novo c.1509dupA:p.R503fs mutation of FUS: report of a girl with sporadic juvenile amyotrophic lateral sclerosis.
Respiratory Syncytial Virus Infections
Approved Antiviral Drugs over the Past 50 Years.
Respiratory Tract Diseases
SARS-CoV-2 Infection and Antibody Response in a Symptomatic Cat from Italy with Intestinal B-Cell Lymphoma.
Respiratory Tract Infections
Randomised controlled trial for high-dose intravenous zinc as adjunctive therapy in SARS-CoV-2 (COVID-19) positive critically ill patients: trial protocol.
Respiratory Tract Infections
Seroepidemiology of human bocavirus in Hokkaido prefecture, Japan.
Reticuloendotheliosis, Avian
RNA polymerase activity in purified virions of avian reticuloendotheliosis viruses.
Retinoblastoma
A locking mechanism regulates RNA synthesis and host protein interaction by the hepatitis C virus polymerase.
Retinoblastoma
Analysis of putative interactions between potyviral replication proteins and plant retinoblastoma proteins.
Retinoblastoma
Down-regulation of the retinoblastoma tumor suppressor by the hepatitis C virus NS5B RNA-dependent RNA polymerase.
Retinoblastoma
Hepatitis C virus induces E6AP-dependent degradation of the retinoblastoma protein.
Retinoblastoma
Retinoblastoma protein disrupts interactions required for RNA polymerase III transcription.
Retinoblastoma
The interaction of nonstructural protein 9 with retinoblastoma protein benefits the replication of genotype 2 porcine reproductive and respiratory syndrome virus in vitro.
Retroviridae Infections
Systemic Expression of a Viral RdRP Protects Against Retrovirus Infection and Disease.
Reye Syndrome
The viral mechanism of Reye's syndrome.
Rhabdomyosarcoma
Distinct roles for the RNA-binding protein Staufen1 in prostate cancer.
Rhabdomyosarcoma
Enhanced potency and efficacy of 29-mer shRNAs in inhibition of Enterovirus 71.
Rhabdomyosarcoma, Alveolar
Differential regulation of autophagy by STAU1 in alveolar rhabdomyosarcoma and non-transformed skeletal muscle cells.
Rheumatic Diseases
The Ro 60 kDa autoantigen comes into focus: interpreting epitope mapping experiments on the basis of structure.
Rheumatic Diseases
The Ro 60 kDa autoantigen: insights into cellular function and role in autoimmunity.
Rhinitis
Homology Modeling and Analysis of Structure Predictions of the Bovine Rhinitis B Virus RNA Dependent RNA Polymerase (RdRp).
Rhinitis, Allergic
Theophylline inhibits the production of nitric oxide by peripheral blood mononuclear cells from patients with asthma.
Rift Valley Fever
A SAP30 complex inhibits IFN-beta expression in Rift Valley fever virus infected cells.
Rift Valley Fever
Generation and characterization of a recombinant Rift Valley fever virus expressing a V5 epitope-tagged RNA-dependent RNA polymerase.
Rift Valley Fever
Genetic evidence for an interferon-antagonistic function of rift valley fever virus nonstructural protein NSs.
Rift Valley Fever
Isolation and Identification of a Novel Phlebovirus, Hedi Virus, from Sandflies Collected in China.
Rift Valley Fever
Rift valley fever virus nonstructural protein NSs promotes viral RNA replication and transcription in a minigenome system.
Rift Valley Fever
RNA polymerase I-mediated expression of viral RNA for the rescue of infectious virulent and avirulent Rift Valley fever viruses.
Rift Valley Fever
Targeting TFIIH to inhibit host cell transcription by Rift Valley Fever Virus.
Rift Valley Fever
The C-terminal region of Rift Valley fever virus NSm protein targets the protein to the mitochondrial outer membrane and exerts antiapoptotic function.
Rift Valley Fever
The carboxy-terminal acidic domain of Rift Valley Fever virus NSs protein is essential for the formation of filamentous structures but not for the nuclear localization of the protein.
Rift Valley Fever
The nonstructural protein NSs induces a variable antibody response in domestic ruminants naturally infected with Rift Valley fever virus.
Rift Valley Fever
The Rift Valley fever virus nonstructural protein NSs is phosphorylated at serine residues located in casein kinase II consensus motifs in the carboxy-terminus.
Rift Valley Fever
The S segment of rift valley fever phlebovirus (Bunyaviridae) carries determinants for attenuation and virulence in mice.
Rift Valley Fever
Virulence factor NSs of rift valley fever virus recruits the F-box protein FBXO3 to degrade subunit p62 of general transcription factor TFIIH.
Rinderpest
A carboxy terminal domain of the L protein of rinderpest virus possesses RNA triphosphatase activity - The first enzyme in the viral mRNA capping pathway.
Rinderpest
Complete genome sequence of transmissible gastroenteritis coronavirus PUR46-MAD clone and evolution of the purdue virus cluster.
Rinderpest
Development of a reconstitution system for Rinderpest virus RNA synthesis in vitro.
Rinderpest
Evidence for N? guanine methyl transferase activity encoded within the modular domain of RNA-dependent RNA polymerase L of a Morbillivirus.
Rinderpest
Phosphoprotein P of Rinderpest virus binds to plus sense leader RNA: regulation by phosphorylation.
Rinderpest
Rational attenuation of a morbillivirus by modulating the activity of the RNA-dependent RNA polymerase.
Rinderpest
Rinderpest virus RNA polymerase subunits: mapping of mutual interacting domains on the large protein L and phosphoprotein p.
Rinderpest
RNA trisphosphatase and guanylyl transferase activities are associated with the RNA polymerase protein L of Rinderpest virus.
Rinderpest
The RNA triphosphatase domain of L protein of Rinderpest virus exhibits pyrophosphatase and tripolyphosphatase activities.
ring-type e3 ubiquitin transferase deficiency
Uncovering the Translational Regulatory Activity of the Tumor Suppressor BRCA1.
RNA Virus Infections
A promising antiviral candidate drug for the COVID-19 pandemic: A mini-review of remdesivir.
RNA Virus Infections
Incorporation fidelity of the viral RNA-dependent RNA polymerase: a kinetic, thermodynamic and structural perspective.
RNA Virus Infections
RNA-dependent RNA polymerase (RdRp) inhibitors: The current landscape and repurposing for the COVID-19 pandemic.
RNA Virus Infections
Staufen1 Protein Participates Positively in the Viral RNA Replication of Enterovirus 71.
RNA Virus Infections
The transcription factor FoxK participates with Nup98 to regulate antiviral gene expression.
rna-directed rna polymerase deficiency
Aminoacyl-Transfer RNA Synthetase Deficiency Promotes Angiogenesis via the Unfolded Protein Response Pathway.
rna-directed rna polymerase deficiency
In vitro transcriptase deficiency of temperature-dependent host range mutants of Chandipura virus.
Rotavirus Infections
MiR-525-3p mediates antiviral defense to rotavirus infection by targeting nonstructural protein 1.
Rotavirus Infections
Rotavirus infection induces the unfolded protein response of the cell and controls it through the nonstructural protein NSP3.
Rubella
Complementation of a deletion in the rubella virus p150 nonstructural protein by the viral capsid protein.
Rubella
Computer-assisted assignment of functional domains in the nonstructural polyprotein of hepatitis E virus: delineation of an additional group of positive-strand RNA plant and animal viruses.
Rubella
Expression of the rubella virus nonstructural protein ORF and demonstration of proteolytic processing.
Rubella
Identification of a Ca2+-binding domain in the rubella virus nonstructural protease.
Rubella
Identification of the rubella virus nonstructural proteins.
Rubella
Intracellular distribution of rubella virus nonstructural protein P150.
Rubella
Live attenuated rubella viral vectors stably express HIV and SIV vaccine antigens while reaching high titers.
Rubella
Mutational analysis of the rubella virus nonstructural polyprotein and its cleavage products in virus replication and RNA synthesis.
Rubella
Mutations in the GDD motif of rubella virus putative RNA-dependent RNA polymerase affect virus replication.
Rubella
Polymerase IV Plays a Crucial Role in Pollen Development in Capsella.
Rubella
Proteolytic processing of rubella virus nonstructural proteins.
Rubella
Rubella virus nonstructural protein 2 is a minor immunogen.
Rubella
Rubella virus nonstructural protein protease domains involved in trans- and cis-cleavage activities.
Rubella
Rubella virus RNA replication is cis-preferential and synthesis of negative- and positive-strand RNAs is regulated by the processing of nonstructural protein.
Rubella
The Rubella Virus Capsid protein inhibits Mitochondrial Import.
Sarcoma
A cytoplasmic long noncoding RNA LINC00470 as a new AKT activator to mediate glioblastoma cell autophagy.
Sarcoma
A de novo c.1509dupA:p.R503fs mutation of FUS: report of a girl with sporadic juvenile amyotrophic lateral sclerosis.
Sarcoma
A renal cell carcinoma with EWSR1-TFE3 fusion gene.
Sarcoma
A universal probe design for colorimetric detection of single-nucleotide variation with visible readout and high specificity.
Sarcoma
Aberrant interaction of FUS with the U1 snRNA provides a molecular mechanism of FUS induced amyotrophic lateral sclerosis.
Sarcoma
ALS/FTLD-Linked Mutations in FUS Glycine Residues Cause Accelerated Gelation and Reduced Interactions with Wild-Type FUS.
Sarcoma
Amyloid-Forming Segment Induces Aggregation of FUS-LC Domain from Phase Separation Modulated by Site-Specific Phosphorylation.
Sarcoma
Autosomal dominant inheritance of rapidly progressive amyotrophic lateral sclerosis due to a truncation mutation in the fused in sarcoma (FUS) gene.
Sarcoma
Binding of Escherichia coli RNA polymerase to a specific site located near the 3'-end of the avaian sarcoma virus genome.
Sarcoma
Characteristic Features of FUS Inclusions in Spinal Motor Neurons of Sporadic Amyotrophic Lateral Sclerosis.
Sarcoma
Characterization of RNA polymerases from Rous sarcoma virus-induced mouse ascites sarcoma cells.
Sarcoma
CHOP/GADD153 and methionyl-tRNA synthetase (MetRS) genes overlap in a conserved region that controls mRNA stability.
Sarcoma
Development of a mouse monoclonal antibody for the detection of asymmetric dimethylarginine of Translocated in LipoSarcoma/FUsed in Sarcoma and its application in analyzing methylated TLS.
Sarcoma
Expression of Fused in sarcoma mutations in mice recapitulates the neuropathology of FUS proteinopathies and provides insight into disease pathogenesis.
Sarcoma
Functional characterization of a FUS mutant zebrafish line as a novel genetic model for ALS.
Sarcoma
FUS inclusions disrupt RNA localization by sequestering kinesin-1 and inhibiting microtubule detyrosination.
Sarcoma
FUS Regulates Activity of MicroRNA-Mediated Gene Silencing.
Sarcoma
FUS regulates genes coding for RNA-binding proteins in neurons by binding to their highly conserved introns.
Sarcoma
FUS-mediated regulation of alternative RNA processing in neurons: insights from global transcriptome analysis.
Sarcoma
Fused in sarcoma regulates DNA replication timing and kinetics.
Sarcoma
Fusion of the RBP56 and CHN genes in extraskeletal myxoid chondrosarcomas with translocation t(9;17)(q22;q11).
Sarcoma
Fusion protein EWS-FLI1 is incorporated into a protein granule in cells.
Sarcoma
HuR/ELAVL1 drives malignant peripheral nerve sheath tumor growth and metastasis.
Sarcoma
lncRNA DUXAP8 Facilitates Multiple Malignant Phenotypes and Resistance to PARP Inhibitor in HCC via Upregulating FOXM1.
Sarcoma
Lysine acetylation regulates the RNA binding, subcellular localization and inclusion formation of FUS.
Sarcoma
Minor intron splicing is regulated by FUS and affected by ALS-associated FUS mutants.
Sarcoma
Modulation of autophagy by miRNAs.
Sarcoma
Motor neuron apoptosis and neuromuscular junction perturbation are prominent features in a Drosophila model of Fus-mediated ALS.
Sarcoma
Multistep process of FUS aggregation in the cell cytoplasm involves RNA-dependent and RNA-independent mechanisms.
Sarcoma
N-terminal acetylation modestly enhances phase separation and reduces aggregation of the low-complexity domain of RNA-binding protein fused in sarcoma.
Sarcoma
Neuron-to-Neuron Transfer of FUS in Drosophila Primary Neuronal Culture Is Enhanced by ALS-Associated Mutations.
Sarcoma
Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites.
Sarcoma
Optineurin immunoreactivity in neuronal and glial intranuclear inclusions in adult-onset neuronal intranuclear inclusion disease.
Sarcoma
Phosphorylation of the FUS low-complexity domain disrupts phase separation, aggregation, and toxicity.
Sarcoma
Pressure and Temperature Phase Diagram for Liquid-Liquid Phase Separation of the RNA-Binding Protein Fused in Sarcoma.
Sarcoma
Reactive astrocytes secrete lcn2 to promote neuron death.
Sarcoma
Residue-by-Residue View of In Vitro FUS Granules that Bind the C-Terminal Domain of RNA Polymerase II.
Sarcoma
Sequence Determines the Switch in the Fibril Forming Regions in the Low-Complexity FUS Protein and Its Variants.
Sarcoma
Severe respiratory changes at end stage in a FUS-induced disease state in adult rats.
Sarcoma
Specific aromatic foldamers potently inhibit spontaneous and seeded A?42 and A?43 fibril assembly.
Sarcoma
Structure of FUS Protein Fibrils and Its Relevance to Self-Assembly and Phase Separation of Low-Complexity Domains.
Sarcoma
The Expression of Insulin-Like Growth Factor 2 Messenger RNA-Binding Protein 3 in Langerhans Cell Histiocytosis and Langerhans Cell Sarcoma.
Sarcoma
The Long Noncoding RNA RP11-728F11.4 Promotes Atherosclerosis.
Sarcoma
The RNA-binding protein FUS is chaperoned and imported into the nucleus by a network of import receptors.
Sarcoma
The RNA-binding Protein Fused in Sarcoma (FUS) Functions Downstream of Poly(ADP-ribose) Polymerase (PARP) in Response to DNA Damage.
Sarcoma
Translocated in liposarcoma regulates the distribution and function of mammalian enabled, a modulator of actin dynamics.
Sarcoma
Uvrag targeting by Mir125a and Mir351 modulates autophagy associated with Ewsr1 deficiency.
Sarcoma
[Experimental study of hematopoietic cell gene expression profile induced by panax notoginosides in vitro]
Sarcoma
[Molecular mechanisms of the biological effects of weak magnetic fields. V. Inactivation in vitro of recombinant Rous sarcoma virus reverse transcriptase under the combined action of weak direct and low-frequency alternating magnetic fields, adjusted to the cyclotron resonance of polar amino acid ions]
Sarcoma, Avian
An electron microscopic method for the mapping of proteins attached to nucleic acids.
Sarcoma, Avian
Characterization of RNA polymerases from Rous sarcoma virus-induced mouse ascites sarcoma cells.
Sarcoma, Avian
Identification of a transformation-specific protein induced by a Rous sarcoma virus.
Sarcoma, Avian
Mode of inhibition of herpes simplex virus DNA polymerase by phosphonoacetate.
Sarcoma, Avian
[Molecular mechanisms of the biological effects of weak magnetic fields. V. Inactivation in vitro of recombinant Rous sarcoma virus reverse transcriptase under the combined action of weak direct and low-frequency alternating magnetic fields, adjusted to the cyclotron resonance of polar amino acid ions]
Sarcoma, Avian
[RNA-dependent RNA-polymerase in virions of Rous sarcoma virus]
Sarcoma, Clear Cell
A renal cell carcinoma with EWSR1-TFE3 fusion gene.
Sarcoma, Ewing
A trans-acting factor, isolated by the three-hybrid system, that influences alternative splicing of the amyloid precursor protein minigene.
Sarcoma, Ewing
An RNA-binding protein gene, TLS/FUS, is fused to ERG in human myeloid leukemia with t(16;21) chromosomal translocation.
Sarcoma, Ewing
Analysis of the DNA-binding and transcriptional activation functions of human Fli-1 protein.
Sarcoma, Ewing
Characterization of a Family of RanBP2-Type Zinc Fingers that Can Recognize Single-Stranded RNA.
Sarcoma, Ewing
Cotranscriptional exon skipping in the genotoxic stress response.
Sarcoma, Ewing
Cutaneous syncytial myoepithelioma: A case report with emphasis on the differential diagnosis of problematic dermal tumors.
Sarcoma, Ewing
Cutting Edge: The RNA-Binding Protein Ewing Sarcoma Is a Novel Modulator of Lymphotoxin ? Receptor Signaling.
Sarcoma, Ewing
Cytomorphology and immunohistochemistry of a recurrent clear cell odontogenic carcinoma with molecular analysis: A case report with review of literature.
Sarcoma, Ewing
Ewing sarcoma gene EWS is essential for meiosis and B lymphocyte development.
Sarcoma, Ewing
EWS represses cofilin 1 expression by inducing nuclear retention of cofilin 1 mRNA.
Sarcoma, Ewing
EWSR1 and ATF1 rearrangements in clear cell odontogenic carcinoma: presentation of a case.
Sarcoma, Ewing
Exenteration and Custom Implant Brachytherapy as a Treatment for Recurrent Primary Extraskeletal Orbital Ewing Sarcoma.
Sarcoma, Ewing
Expression of the EWS/FLI-1 oncogene in murine primary bone-derived cells Results in EWS/FLI-1-dependent, ewing sarcoma-like tumors.
Sarcoma, Ewing
Functional Genomic Screening Reveals Splicing of the EWS-FLI1 Fusion Transcript as a Vulnerability in Ewing Sarcoma.
Sarcoma, Ewing
Fusion of CHOP to a novel RNA-binding protein in human myxoid liposarcoma.
Sarcoma, Ewing
Fusion protein EWS-FLI1 is incorporated into a protein granule in cells.
Sarcoma, Ewing
HNRNPH1-dependent splicing of a fusion oncogene reveals a targetable RNA G-quadruplex interaction.
Sarcoma, Ewing
Identification of Ewing's sarcoma protein as a G-quadruplex DNA- and RNA-binding protein.
Sarcoma, Ewing
Insulin-Like Growth Factor 2 mRNA-Binding Protein 3 is a Novel Post-Transcriptional Regulator of Ewing Sarcoma Malignancy.
Sarcoma, Ewing
Long noncoding RNA EWSAT1-mediated gene repression facilitates Ewing sarcoma oncogenesis.
Sarcoma, Ewing
Nuclear Leukocyte Immunoglobulin-like Receptor A3 Is Monomeric and Is Involved in Multiple Layers of Regulated Gene Expression and Translation.
Sarcoma, Ewing
Pharmaceutical Interference of the EWS-FLI1-driven Transcriptome By Cotargeting H3K27ac and RNA Polymerase Activity in Ewing Sarcoma.
Sarcoma, Ewing
Spinal cord astroblastoma with EWSR1-BEND2 fusion classified as HGNET-MN1 by methylation classification: a case report.
Sarcoma, Ewing
Structure-Function Based Molecular Relationships in Ewing's Sarcoma.
Sarcoma, Ewing
Tyrosine kinase Pyk2 mediates G-protein-coupled receptor regulation of the Ewing sarcoma RNA-binding protein EWS.
Sarcoma, Ewing
Tyrosine Phosphorylation in the C-Terminal Nuclear Localization and Retention Signal (C-NLS) of the EWS Protein.
Sarcoma, Yoshida
The effect of dibromodulcitol on the template activity of DNA chromatin and nuclei from Yoshida sarcoma cells.
Scleroderma, Localized
RNA polymerase III-positive systemic sclerosis in a patient with circumscribed morphea.
Scleroderma, Systemic
Paraneoplastic Scleroderma: Are There Any Clues?
Scleroderma, Systemic
RNA polymerase III-positive systemic sclerosis in a patient with circumscribed morphea.
Scrapie
An antibiotic dependent conditional lethal mutant with a lesion affecting transcription and translation.
Seizures
Aberrant sodium channel activity in the complex seizure disorder of Celf4 mutant mice.
Seizures
Absence of RNA-binding protein FXR2P prevents prolonged phase of kainate-induced seizures.
Seizures
Alteration of RNA synthesis in vitro in intact cerebral cortex nuclei induced by convulsions in seizure-susceptible El mice.
Seizures
Complex seizure disorder caused by Brunol4 deficiency in mice.
Seizures
Etiology of a genetically complex seizure disorder in Celf4 mutant mice.
Seizures
MDH2 is an RNA binding protein involved in downregulation of sodium channel Scn1a expression under seizure condition.
Seizures
RNA Polymerase 1 Is Transiently Regulated by Seizures and Plays a Role in a Pharmacological Kindling Model of Epilepsy.
Sepsis
A cold-inducible RNA-binding protein (CIRP)-derived peptide attenuates inflammation and organ injury in septic mice.
Sepsis
Abundance of the {delta} Subunit of RNA Polymerase Is Linked to the Virulence of Streptococcus agalactiae.
Sepsis
Blocking cold-inducible RNA-binding protein protects liver from ischemia-reperfusion injury.
Sepsis
Cirp Induces Neutrophil Reverse Transendothelial Migration in Sepsis.
Sepsis
Cold-inducible RNA-binding protein (CIRP) causes sepsis-associated acute lung injury via induction of endoplasmic reticulum stress.
Sepsis
Cold-inducible RNA-binding protein (CIRP) triggers inflammatory responses in hemorrhagic shock and sepsis.
Sepsis
Cold-inducible RNA-binding protein activates splenic T cells during sepsis in a TLR4-dependent manner.
Sepsis
Cold-inducible RNA-binding protein causes endothelial dysfunction via activation of Nlrp3 inflammasome.
Sepsis
Cold-inducible RNA-binding Protein Induces Neutrophil Extracellular Traps in the Lungs during Sepsis.
Sepsis
Damage-Associated Molecular Patterns as Double-Edged Swords in Sepsis.
Sepsis
Extracellular CIRP Induces Inflammation in Alveolar Type II Cells via TREM-1.
Sepsis
Extracellular microRNA 130b-3p inhibits eCIRP-induced inflammation.
Sepsis
The Cold-Inducible RNA-Binding Protein (CIRP) Level in Peripheral Blood Predicts Sepsis Outcome.
Severe Acute Respiratory Syndrome
"Bucket brigade" using lysine residues in RNA-dependent RNA polymerase of SARS-CoV-2.
Severe Acute Respiratory Syndrome
A mini-review on sofosbuvir and daclatasvir treatment in coronavirus disease 2019.
Severe Acute Respiratory Syndrome
A nanoscale genosensor for early detection of COVID-19 by voltammetric determination of RNA-dependent RNA polymerase (RdRP) sequence of SARS-CoV-2 virus.
Severe Acute Respiratory Syndrome
A promising antiviral candidate drug for the COVID-19 pandemic: A mini-review of remdesivir.
Severe Acute Respiratory Syndrome
Allosteric Activation of SARS-CoV-2 RNA-Dependent RNA Polymerase by Remdesivir Triphosphate and Other Phosphorylated Nucleotides.
Severe Acute Respiratory Syndrome
Biochemical characterization of a recombinant SARS coronavirus nsp12 RNA-dependent RNA polymerase capable of copying viral RNA templates.
Severe Acute Respiratory Syndrome
Brief comparative evaluation of six open one-step RT-qPCR mastermixes for the detection of SARS-CoV-2 RNA using a Taqman probe.
Severe Acute Respiratory Syndrome
Characterization of the guanine-N7 methyltransferase activity of coronavirus nsp14 on nucleotide GTP.
Severe Acute Respiratory Syndrome
Characterization of the NiRAN domain from RNA-dependent RNA polymerase provides insights into a potential therapeutic target against SARS-CoV-2.
Severe Acute Respiratory Syndrome
Chemical constituents from coconut waste and their in silico evaluation as potential antiviral agents against SARS-CoV-2.
Severe Acute Respiratory Syndrome
Comparative Evaluation of Tears and Nasopharyngeal Swab for SARS-CoV-2 in COVID-19 Dedicated Intensive Care Unit Patients.
Severe Acute Respiratory Syndrome
Comparative in vivo analysis of the nsp15 endoribonuclease of murine, porcine and severe acute respiratory syndrome coronaviruses.
Severe Acute Respiratory Syndrome
Comprehensive structural analysis of designed incomplete polypeptide chains of the replicase nonstructural protein 1 from the severe acute respiratory syndrome coronavirus.
Severe Acute Respiratory Syndrome
Conserved HLA binding peptides from five non-structural proteins of SARS-CoV-2-An in silico glance.
Severe Acute Respiratory Syndrome
Coronavirus genomic nsp14-ExoN, structure, role, mechanism, and potential application as a drug target.
Severe Acute Respiratory Syndrome
Coronavirus replication-transcription complex: Vital and selective NMPylation of a conserved site in nsp9 by the NiRAN-RdRp subunit.
Severe Acute Respiratory Syndrome
Crystal structure of nonstructural protein 10 from the severe acute respiratory syndrome coronavirus reveals a novel fold with two zinc-binding motifs.
Severe Acute Respiratory Syndrome
Delayed Development of Coronary Artery Dilitation in Suspected Severe Acute Respiratory Syndrome Coronavirus 2 Multisystem Inflammatory Syndrome: More Research Needed.
Severe Acute Respiratory Syndrome
Development of a Simple In Vitro Assay To Identify and Evaluate Nucleotide Analogs against SARS-CoV-2 RNA-Dependent RNA Polymerase.
Severe Acute Respiratory Syndrome
Discovery of (E)-N-(4-cyanobenzylidene)- 6-fluoro- 3-hydroxypyrazine-2 -carboxamide (cyanorona-20): the first potent and specific anti-COVID-19 drug.
Severe Acute Respiratory Syndrome
Dodecamer structure of severe acute respiratory syndrome coronavirus nonstructural protein nsp10.
Severe Acute Respiratory Syndrome
Evaluating the potential of different inhibitors on RNA-dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2: A molecular modeling approach.
Severe Acute Respiratory Syndrome
Fe-S cofactors in the SARS-CoV-2 RNA-dependent RNA polymerase are potential antiviral targets.
Severe Acute Respiratory Syndrome
Functional screen reveals SARS coronavirus nonstructural protein nsp14 as a novel cap N7 methyltransferase.
Severe Acute Respiratory Syndrome
High Fidelity of Murine Hepatitis Virus Replication Is Decreased in nsp14 Exoribonuclease Mutants.
Severe Acute Respiratory Syndrome
High-resolution structure and biophysical characterization of the nucleocapsid phosphoprotein dimerization domain from the Covid-19 severe acute respiratory syndrome coronavirus 2.
Severe Acute Respiratory Syndrome
Human microRNA hsa-miR-15b-5p targets the RNA template component of the RNA-dependent RNA polymerase structure in severe acute respiratory syndrome coronavirus 2.
Severe Acute Respiratory Syndrome
Immunoinformatics approach for multi-epitope vaccine design against structural proteins and ORF1a polyprotein of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2).
Severe Acute Respiratory Syndrome
In silico investigation to identify potential small molecule inhibitors of the RNA-dependent RNA polymerase (RdRp) nidovirus RdRp-associated nucleotidyltransferase domain.
Severe Acute Respiratory Syndrome
Infectious Bronchitis Coronavirus Limits Interferon Production by Inducing a Host Shutoff That Requires Accessory Protein 5b.
Severe Acute Respiratory Syndrome
Interface-based design of the favipiravir-binding site in SARS-CoV-2 RNA-dependent RNA polymerase reveals mutations conferring resistance to chain termination.
Severe Acute Respiratory Syndrome
Interference of ribosomal frameshifting by antisense peptide nucleic acids suppresses SARS coronavirus replication.
Severe Acute Respiratory Syndrome
Is oseltamivir suitable for fighting against COVID-19: In silico assessment, in vitro and retrospective study.
Severe Acute Respiratory Syndrome
Mass spectrometric based detection of protein nucleotidylation in the RNA polymerase of SARS-CoV-2.
Severe Acute Respiratory Syndrome
MAVS-mediated apoptosis and its inhibition by viral proteins.
Severe Acute Respiratory Syndrome
Micronutrients and bioactive substances: Their potential roles in combating COVID-19.
Severe Acute Respiratory Syndrome
Molnupiravir promotes SARS-CoV-2 mutagenesis via the RNA template.
Severe Acute Respiratory Syndrome
Multivalent binding of the partially disordered SARS-CoV-2 nucleocapsid phosphoprotein dimer to RNA.
Severe Acute Respiratory Syndrome
Natural plant products as potential inhibitors of RNA dependent RNA polymerase of Severe Acute Respiratory Syndrome Coronavirus-2.
Severe Acute Respiratory Syndrome
NeoCoV Is Closer to MERS-CoV than SARS-CoV.
Severe Acute Respiratory Syndrome
NMR Structure of the SARS-CoV Nonstructural Protein 7 in Solution at pH 6.5.
Severe Acute Respiratory Syndrome
Novel beta-barrel fold in the nuclear magnetic resonance structure of the replicase nonstructural protein 1 from the severe acute respiratory syndrome coronavirus.
Severe Acute Respiratory Syndrome
Novel Development of Predictive Feature Fingerprints to Identify Chemistry-Based Features for the Effective Drug Design of SARS-CoV-2 Target Antagonists and Inhibitors Using Machine Learning.
Severe Acute Respiratory Syndrome
Nuclear magnetic resonance structure of the N-terminal domain of nonstructural protein 3 from the severe acute respiratory syndrome coronavirus.
Severe Acute Respiratory Syndrome
One severe acute respiratory syndrome coronavirus protein complex integrates processive RNA polymerase and exonuclease activities.
Severe Acute Respiratory Syndrome
One-pot pre-coated interface proximity extension assay for ultrasensitive co-detection of anti-SARS-CoV-2 antibodies and viral RNA.
Severe Acute Respiratory Syndrome
Plant-derived exosomal microRNAs inhibit lung inflammation induced by exosomes SARS-CoV-2 Nsp12.
Severe Acute Respiratory Syndrome
Prediction of Small Molecule Inhibitors Targeting the Severe Acute Respiratory Syndrome Coronavirus-2 RNA-dependent RNA Polymerase.
Severe Acute Respiratory Syndrome
Rational engineering the DNA tetrahedrons of dual wavelength ratiometric electrochemiluminescence biosensor for high efficient detection of SARS-CoV-2 RdRp gene by using entropy-driven and bipedal DNA walker amplification strategy.
Severe Acute Respiratory Syndrome
Remdesivir (GS-5734) in COVID-19 Therapy: The Fourth Chance.
Severe Acute Respiratory Syndrome
Remdesivir analogs against SARS-CoV-2 RNA-dependent RNA polymerase.
Severe Acute Respiratory Syndrome
Remdesivir is a direct-acting antiviral that inhibits RNA-dependent RNA polymerase from severe acute respiratory syndrome coronavirus 2 with high potency.
Severe Acute Respiratory Syndrome
RNA 3'-end mismatch excision by the severe acute respiratory syndrome coronavirus nonstructural protein nsp10/nsp14 exoribonuclease complex.
Severe Acute Respiratory Syndrome
Role for nonstructural protein 1 of severe acute respiratory syndrome coronavirus in chemokine dysregulation.
Severe Acute Respiratory Syndrome
SARS coronavirus protein nsp1 disrupts localization of Nup93 from the nuclear pore complex.
Severe Acute Respiratory Syndrome
Sequence requirements of the FFAT-like motif for specific binding to VAP-A are revealed by NMR.
Severe Acute Respiratory Syndrome
Severe acute respiratory syndrome coronavirus protein nsp1 is a novel eukaryotic translation inhibitor that represses multiple steps of translation initiation.
Severe Acute Respiratory Syndrome
Structural and molecular basis of mismatch correction and ribavirin excision from coronavirus RNA.
Severe Acute Respiratory Syndrome
Structural Basis and Function of the N Terminus of SARS-CoV-2 Nonstructural Protein 1.
Severe Acute Respiratory Syndrome
Structural basis for backtracking by the SARS-CoV-2 replication-transcription complex.
Severe Acute Respiratory Syndrome
Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome.
Severe Acute Respiratory Syndrome
Structure of replicating SARS-CoV-2 polymerase.
Severe Acute Respiratory Syndrome
Structure of the SARS-CoV-2 RNA-dependent RNA polymerase in the presence of favipiravir-RTP.
Severe Acute Respiratory Syndrome
Targeting the RdRp of Emerging RNA Viruses: The Structure-Based Drug Design Challenge.
Severe Acute Respiratory Syndrome
Template-dependent inhibition of coronavirus RNA-dependent RNA polymerase by remdesivir reveals a second mechanism of action.
Severe Acute Respiratory Syndrome
The potential chemical structure of anti-SARS-CoV-2 RNA-dependent RNA polymerase.
Severe Acute Respiratory Syndrome
The potential of Paritaprevir and Emetine as inhibitors of SARS-CoV-2 RdRp.
Severe Acute Respiratory Syndrome
The RNA polymerase activity of SARS-coronavirus nsp12 is primer dependent.
Severe Acute Respiratory Syndrome
The SARS coronavirus nucleocapsid protein--forms and functions.
Severe Acute Respiratory Syndrome
The severe acute respiratory syndrome coronavirus Nsp15 protein is an endoribonuclease that prefers manganese as a cofactor.
Severe Acute Respiratory Syndrome
Theoretical Analysis Reveals the Cost and Benefit of Proofreading in Coronavirus Genome Replication.
Severe Acute Respiratory Syndrome
Third force in the treatment of COVID-19: A systematic review and meta-analysis.
Severe Acute Respiratory Syndrome
Viral targets of acylguanidines.
Severe Dengue
A T164S mutation in the dengue virus NS1 protein is associated with greater disease severity in mice.
Severe Dengue
An Evidence-Based Algorithm for Early Prognosis of Severe Dengue in the Outpatient Setting.
Severe Dengue
Cyclic Dinucleotide-Adjuvanted Dengue Virus Nonstructural Protein 1 Induces Protective Antibody and T Cell Responses.
Severe Dengue
Differentially expressed genes of human microvascular endothelial cells in response to anti-dengue virus NS1 antibodies by suppression subtractive hybridization.
Severe Dengue
Elevated dengue virus nonstructural protein 1 serum levels and altered toll-like receptor 4 expression, nitric oxide, and tumor necrosis factor alpha production in dengue hemorrhagic Fever patients.
Severe Dengue
High circulating levels of the dengue virus nonstructural protein NS1 early in dengue illness correlate with the development of dengue hemorrhagic fever.
Severe Dengue
High levels of serum hyaluronan is an early predictor of dengue warning signs and perturbs vascular integrity.
Severe Dengue
How NS1 Antibodies Prevent Severe Flavivirus Disease.
Severe Dengue
Nonstructural protein NS1 immunodominant epitope detected specifically in dengue virus infected material by a SELDI-TOF/MS based assay.
Severe Dengue
Nucleotide sequences of the nonstructural protein NS1 gene of three dengue-2 viruses, M1, M2 and M3, isolated in Malaysia from patients with dengue haemorrhagic fever, dengue shock syndrome and dengue fever, respectively.
Severe Fever with Thrombocytopenia Syndrome
Hijacking of RIG-I Signaling Proteins into Virus-Induced Cytoplasmic Structures Correlates with the Inhibition of Type I Interferon Responses.
Severe Fever with Thrombocytopenia Syndrome
Nonstructural Protein NSs Hampers Cellular Antiviral Response through LSm14A during Severe Fever with Thrombocytopenia Syndrome Virus Infection.
Severe Fever with Thrombocytopenia Syndrome
Nonstructural Protein of Severe Fever with Thrombocytopenia Syndrome Phlebovirus Inhibits TBK1 to Evade Interferon-Mediated Response.
Severe Fever with Thrombocytopenia Syndrome
Nonstructural protein of severe fever with thrombocytopenia syndrome phlebovirus targets STAT2 and not STAT1 to inhibit type I interferon-stimulated JAK-STAT signaling.
Severe Fever with Thrombocytopenia Syndrome
Roles of viroplasm-like structures formed by nonstructural protein NSs in infection with severe fever with thrombocytopenia syndrome virus.
Severe Fever with Thrombocytopenia Syndrome
Severe Fever with Thrombocytopenia Syndrome Virus NSs Interacts with TRIM21 To Activate the p62-Keap1-Nrf2 Pathway.
Severe Fever with Thrombocytopenia Syndrome
Suppression of the IFN-? and -? Induction through Sequestering IRF7 into Viral Inclusion Bodies by Nonstructural Protein NSs in Severe Fever with Thrombocytopenia Syndrome Bunyavirus Infection.
Severe Fever with Thrombocytopenia Syndrome
Two Conserved Amino Acids within the NSs of Severe Fever with Thrombocytopenia Syndrome Phlebovirus Are Essential for Anti-interferon Activity.
Shock, Septic
Cold-inducible RNA-binding protein mediates neuroinflammation in cerebral ischemia.
Shwachman-Diamond Syndrome
The Shwachman-Bodian-Diamond syndrome gene encodes an RNA-binding protein that localizes to the pseudopod of Dictyostelium amoebae during chemotaxis.
Sjogren's Syndrome
Phage-displayed La/SS-B antigen as a diagnostic reagent.
Sjogren's Syndrome
The Ro 60 kDa autoantigen comes into focus: interpreting epitope mapping experiments on the basis of structure.
Sjogren's Syndrome
The Ro 60 kDa autoantigen: insights into cellular function and role in autoimmunity.
Skin Diseases
Interaction of BP180 (type XVII collagen) and alpha6 integrin is necessary for stabilization of hemidesmosome structure.
Skin Neoplasms
Cytoplasmic accumulation of the RNA-binding protein HuR stabilizes the ornithine decarboxylase transcript in a murine nonmelanoma skin cancer model.
Sleep Deprivation
Cold-inducible RNA-binding protein (CIRBP) adjusts clock-gene expression and REM-sleep recovery following sleep deprivation.
Small Cell Lung Carcinoma
Application of Serum ELAVL4 (HuD) Antigen Assay for Small Cell Lung Cancer Diagnosis.
Small Cell Lung Carcinoma
KH-type splicing regulatory protein (KHSRP) contributes to tumorigenesis by promoting miR-26a maturation in small cell lung cancer.
Spinal Cord Injuries
Adult neural stem cells and central nervous system repair.
Spinocerebellar Ataxias
Ataxin-2: From RNA Control to Human Health and Disease.
Spinocerebellar Ataxias
Conserved role for Ataxin-2 in mediating endoplasmic reticulum dynamics.
Spinocerebellar Ataxias
Nonapoptotic cell death caused by the inhibition of RNA polymerase disrupts organelle distribution.
Spotted Fever Group Rickettsiosis
Characterization of mutations in the rpoB gene in naturally rifampin-resistant Rickettsia species.
Squamous Cell Carcinoma of Head and Neck
Characterization of squamous cell carcinoma in an organotypic culture via subsurface non-linear optical molecular imaging.
Squamous Cell Carcinoma of Head and Neck
Implication of RNA-binding protein La in proliferation, migration and invasion of lymph node-metastasized hypopharyngeal SCC cells.
Squamous Cell Carcinoma of Head and Neck
Muscle-Specific FXR1 Isoforms in Squamous Cell Cancer.
Squamous Cell Carcinoma of Head and Neck
Repression of caspase-3 and RNA-binding protein HuR cleavage by cyclooxygenase-2 promotes drug resistance in oral squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
RNA-binding protein CELF1 promotes tumor growth and alters gene expression in oral squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
The La protein counteracts cisplatin-induced cell death by stimulating protein synthesis of anti-apoptotic factor Bcl2.
Staphylococcal Infections
Sequencing and staphylococci identification.
Starvation
6S RNA plays a role in recovery from nitrogen depletion in Synechocystis sp. PCC 6803.
Starvation
ALBA proteins are stage regulated during trypanosome development in the tsetse fly and participate in differentiation.
Starvation
Alteration of the growth-rate-dependent regulation of Escherichia coli tyrT expression by promoter mutations.
Starvation
Alterations in DRBD3 ribonucleoprotein complexes in response to stress in Trypanosoma brucei.
Starvation
Amino acid starvation affects the initiation frequency of nucleolar RNA polymerase.
Starvation
Binding interface between the Salmonella ?(S)/RpoS subunit of RNA polymerase and Crl: hints from bacterial species lacking crl.
Starvation
Characterization of four orthologs of stringent starvation protein A.
Starvation
Characterization of the auxin-regulated par gene from tobacco mesophyll protoplasts.
Starvation
Control of ribonucleic acid synthesis in eukaryotes. 2. The effect of protein synthesis on the activities of nuclear and total DNA-dependent RNA polymerase in yeast.
Starvation
DksA represses ribosomal gene transcription in Pseudomonas aeruginosa by interacting with RNA polymerase on ribosomal promoters.
Starvation
DNA polymerase III protein, HolC, helps resolve replication/transcription conflicts.
Starvation
Effects of environmental stresses on the activities of the uspA, grpE and rpoS promoters of Escherichia coli O157:H7.
Starvation
Elevated mutation frequency in surviving populations of carbon-starved rpoS-deficient Pseudomonas putida is caused by reduced expression of superoxide dismutase and catalase.
Starvation
Error-prone DNA polymerase IV is controlled by the stress-response sigma factor, RpoS, in Escherichia coli.
Starvation
Escherichia coli SspA is a transcription activator for bacteriophage P1 late genes.
Starvation
Expanding the RpoS/?S-network by RNA sequencing and identification of ?S-controlled small RNAs in Salmonella.
Starvation
Expression of different-size transcripts from the clpP-clpX operon of Escherichia coli during carbon deprivation.
Starvation
Expression, crystallization and preliminary crystallographic analysis of the PAS domain of RsbP, a stress-response phosphatase from Bacillus subtilis.
Starvation
Fitness costs of rifampicin resistance in Mycobacterium tuberculosis are amplified under conditions of nutrient starvation and compensated by mutation in the ?' subunit of RNA polymerase.
Starvation
Growth phase-dependent expression of the Pseudomonas putida KT2440 transcriptional machinery analysed with a genome-wide DNA microarray.
Starvation
Growth rate regulation in Escherichia coli.
Starvation
Guanosine 3',5'-bispyrophosphate coordinates global gene expression during glucose-lactose diauxie in Escherichia coli.
Starvation
Heat shock regulation of sigmaS turnover: a role for DnaK and relationship between stress responses mediated by sigmaS and sigma32 in Escherichia coli.
Starvation
Increased Bioplastic Production with an RNA Polymerase Sigma Factor SigE during Nitrogen Starvation in Synechocystis sp. PCC 6803.
Starvation
Initiation of transcription-coupled repair characterized at single-molecule resolution.
Starvation
Isolation and characterization of the gene encoding the principal sigma factor of the vegetative cell RNA polymerase from the cyanobacterium Anabaena sp. strain PCC 7120.
Starvation
Magic spots cast a spell on DNA primase.
Starvation
Mechanisms of physiological regulation of RNA synthesis in bacteria: new discoveries breaking old schemes.
Starvation
Mode of initiation of constitutive stable DNA replication in RNase H-defective mutants of Escherichia coli K-12.
Starvation
Modulating RssB activity: IraP, a novel regulator of {sigma}S stability in Escherichia coli.
Starvation
Multiple signaling pathways in gene expression during sugar starvation. Pharmacological analysis of din gene expression in suspension-cultured cells of Arabidopsis.
Starvation
Negative control of rpoS expression by phosphoenolpyruvate: carbohydrate phosphotransferase system in Escherichia coli.
Starvation
Phosphorylation of RNA polymerase I-associated polypeptides of Tetrahymena pyriformis.
Starvation
Polyphosphate binds to the principal sigma factor of RNA polymerase during starvation response in Helicobacter pylori.
Starvation
ppGpp inhibits the activity of Escherichia coli DnaG primase.
Starvation
Regulation in the synthesis of Escherichia coli RNA polymerase proposed from sequence analysis.
Starvation
relA-dependent RNA polymerase activity in Escherichia coli.
Starvation
Role of putrescine in regulation of the sigmaS subunit of RNA polymerase in Escherichia coli cells on transition to stationary phase.
Starvation
Role of the sigma 70 subunit of RNA polymerase in transcriptional activation by activator protein PhoB in Escherichia coli.
Starvation
SigmaS-dependent gene expression at the onset of stationary phase in Escherichia coli: function of sigmaS-dependent genes and identification of their promoter sequences.
Starvation
Structural basis for transcription inhibition by E. coli SspA.
Starvation
Studies in vivo on Escherichia coli RNA polymerase mutants altered in the stringent response.
Starvation
Subunits of RNA polymerase in function and structure. IX. Regulation of RNA polymerase activity by stringent starvation protein (SSP).
Starvation
The effect of cyclic nucleotides on cellular ATP levels and ribosomal RNA synthesis in Ehrlich ascites cells.
Starvation
The mediator for stringent control, ppGpp, binds to the beta-subunit of Escherichia coli RNA polymerase.
Starvation
The RNA antiterminator causes transcription pausing in the leader region of the tryptophan operon.
Starvation
The Role of Replication Clamp-Loader Protein HolC of Escherichia coli in Overcoming Replication/Transcription Conflicts.
Starvation
The role of the omega subunit of RNA polymerase in expression of the relA gene in Escherichia coli.
Starvation
Toxic effects of high levels of ppGpp in Escherichia coli are relieved by rpoB mutations.
Starvation
Transcription of ribosomal component genes and lac in a relA+/relA pair of Escherichia coli strains.
Starvation
Translational regulation of the Escherichia coli stress factor RpoS: a role for SsrA and Lon.
Starvation
Yeast Sporulation and [SMAUG+] Prion: Faster Is Not Always Better.
Starvation
[Differential protein analysis on the root response of rice with high phosphorous uptake efficiency to low phosphorous stress].
Starvation
[Stationary phase in Escherichia coli]
Still's Disease, Adult-Onset
Clinical relevance for circulating cold-inducible RNA-binding protein (CIRP) in patients with adult-onset Still's disease.
Stomach Neoplasms
A Novel RNA-Binding Protein Signature to Predict Clinical Outcomes and Guide Clinical Therapy in Gastric Cancer.
Stomach Neoplasms
LARP7 is a potential tumor suppressor gene in gastric cancer.
Stomach Neoplasms
Long non-coding RNA Loc490 inhibits gastric cancer cell proliferation and metastasis by upregulating RNA-binding protein Quaking.
Stomach Neoplasms
Long noncoding RNA LINC00982 upregulates CTSF expression to inhibit gastric cancer progression via the transcription factor HEY1.
Stomach Neoplasms
NME2 Is a Master Suppressor of Apoptosis in Gastric Cancer Cells via Transcriptional Regulation of miR-100 and Other Survival Factors.
Stomach Neoplasms
Poly(rC) binding protein 2 (PCBP2) promotes the viability of human gastric cancer cells by regulating CDK2.
Stomach Neoplasms
RNA-binding protein RBM38 acts as a tumor suppressor in gastric cancer.
Stomach Neoplasms
RNA-binding protein RNPC1 acts as an oncogene in gastric cancer by stabilizing aurora kinase B mRNA.
Stomach Neoplasms
The Aberrant Expression of MicroRNA-125a-5p/IGF2BP3 Axis in Advanced Gastric Cancer and Its Clinical Relevance.
Stomach Neoplasms
The RNA-Binding Protein DDX18 Promotes Gastric Cancer by Affecting the Maturation of MicroRNA-21.
Stomach Neoplasms
The RNA-Binding Protein NELFE Promotes Gastric Cancer Growth and Metastasis Through E2F2.
Stomatitis
Inhibition of caspases protects mice from radiation-induced oral mucositis and abolishes the cleavage of RNA-binding protein HuR.
Stroke
Analytical theory of the nonequilibrium spatial distribution of RNA polymerase translocations.
Stroke
Monocyte function and plasma levels of interleukin-8 in acute ischemic stroke.
Stroke
The nucleotide addition cycle of the SARS-CoV-2 polymerase.
Stuttering
A mutant RNA polymerase reveals a kinetic mechanisms for the switch between nonproductive stuttering synthesis and productive initiation during promoter clearance.
Stuttering
Genome rearrangement affects RNA virus adaptability on prostate cancer cells.
Stuttering
Nucleotide sequences and mapping of novel heterogenous 5'-termini of adenovirus 2 early region 4 mRNA.
Stuttering
Paramyxovirus mRNA editing leads to G deletions as well as insertions.
Stuttering
The versatility of paramyxovirus RNA polymerase stuttering.
Subacute Sclerosing Panencephalitis
Characterization of an RNA-dependent RNA polymerase activity associated with measles virus.
Subacute Sclerosing Panencephalitis
Effect of promoter mutations and upstream deletions on the expression of genes coding for small, acid-soluble spore proteins of Bacillus subtilis.
Subacute Sclerosing Panencephalitis
Identification of a new sigma-factor involved in compartmentalized gene expression during sporulation of Bacillus subtilis.
Superinfection
A Novel Role for PDZ-Binding Motif of Influenza A Virus Nonstructural Protein 1 in Regulation of Host Susceptibility to Postinfluenza Bacterial Superinfections.
Superinfection
Mutational analysis of influenza virus promoter elements in vivo.
Superinfection
Mutational analysis of the Uukuniemi virus (Bunyaviridae family) promoter reveals two elements of functional importance.
Superinfection
Structural basis of transcription arrest by coliphage HK022 Nun in an
Superinfection
The repeated regions of Semliki Forest virus defective-inferfering RNA interferes with the encapsidation process of the standard virus.
Superinfection
The Y39A mutation of HK022 Nun disrupts a boxB interaction but preserves termination activity.
Swine Vesicular Disease
The N-terminal region of the VP1 protein of swine vesicular disease virus contains a neutralization site that arises upon cell attachment and is involved in viral entry.
Tauopathies
AlphaScreen Identifies MSUT2 Inhibitors for Tauopathy-Targeting Therapeutic Discovery.
TDP-43 Proteinopathies
Structural Transition, Function and Dysfunction of TDP-43 in Neurodegenerative Diseases.
TDP-43 Proteinopathies
TDP-43 repression of nonconserved cryptic exons is compromised in ALS-FTD.
Teratoma
Mammalian germ cells are determined after PGC colonization of the nascent gonad.
Teratoma
The RNA-binding protein DND1 acts sequentially as a negative regulator of pluripotency and a positive regulator of epigenetic modifiers required for germ cell reprogramming.
Teratoma
Translational repression of cyclin E prevents precocious mitosis and embryonic gene activation during C. elegans meiosis.
Thrombocytopenia
Deadly intracranial bleed in patients with dengue fever: A series of nine patients and review of literature.
Thrombocytopenia
Dengue virus nonstructural protein 1 activates platelets via Toll-like receptor 4, leading to thrombocytopenia and hemorrhage.
Thrombocytopenia
Fatal Intracranial Hemorrhage in a Patient with Severe Dengue Fever.
Thrombocytopenia
Hijacking of RIG-I Signaling Proteins into Virus-Induced Cytoplasmic Structures Correlates with the Inhibition of Type I Interferon Responses.
Thrombocytopenia
Nonstructural Protein NSs Hampers Cellular Antiviral Response through LSm14A during Severe Fever with Thrombocytopenia Syndrome Virus Infection.
Thrombocytopenia
Nonstructural Protein of Severe Fever with Thrombocytopenia Syndrome Phlebovirus Inhibits TBK1 to Evade Interferon-Mediated Response.
Thrombocytopenia
Nonstructural protein of severe fever with thrombocytopenia syndrome phlebovirus targets STAT2 and not STAT1 to inhibit type I interferon-stimulated JAK-STAT signaling.
Thrombocytopenia
Roles of viroplasm-like structures formed by nonstructural protein NSs in infection with severe fever with thrombocytopenia syndrome virus.
Thrombocytopenia
Severe Fever with Thrombocytopenia Syndrome Virus NSs Interacts with TRIM21 To Activate the p62-Keap1-Nrf2 Pathway.
Thrombocytopenia
Suppression of the IFN-? and -? Induction through Sequestering IRF7 into Viral Inclusion Bodies by Nonstructural Protein NSs in Severe Fever with Thrombocytopenia Syndrome Bunyavirus Infection.
Thrombocytopenia
Two Conserved Amino Acids within the NSs of Severe Fever with Thrombocytopenia Syndrome Phlebovirus Are Essential for Anti-interferon Activity.
Thrombosis
Lung transcriptome of a COVID-19 patient and systems biology predictions suggest impaired surfactant production which may be druggable by surfactant therapy.
Thrombosis
The Role of PB1 Domain Proteins in Endothelial Cell Dysfunction and Disease.
Thyroid Cancer, Papillary
miR-31 Reduces Cell Growth of Papillary Thyroid Carcinoma by RNA-Binding Protein HuR.
Thyroid Neoplasms
Effects of HuR downregulation on anaplastic thyroid cancer cells.
Thyroid Neoplasms
Identification of tumorigenesis-related mRNAs associated with RNA-binding protein HuR in thyroid cancer cells.
Triple Negative Breast Neoplasms
Long non-coding RNA LINC-PINT attenuates paclitaxel resistance in triple-negative breast cancer cells via targeting the RNA-binding protein NONO.
Triple Negative Breast Neoplasms
RNA-binding protein MSI2 isoforms expression and regulation in progression of triple-negative breast cancer.
Triple Negative Breast Neoplasms
TDP-43 is Required for Mammary Gland Repopulation and Proliferation of Mammary Epithelial Cells.
Triple Negative Breast Neoplasms
Therapeutic targeting of transcriptional cyclin-dependent kinases.
Tuberculosis
A mycobacterial extracytoplasmic function sigma factor involved in survival following stress.
Tuberculosis
A recombinant Mycobacterium tuberculosis in vitro transcription system.
Tuberculosis
A universal probe design for colorimetric detection of single-nucleotide variation with visible readout and high specificity.
Tuberculosis
Alteration of ribosomes and RNA polymerase in drug-resistant clinical isolates of Mycobacterium tuberculosis.
Tuberculosis
Altered Fatty Acid Metabolism Due to Rifampicin-Resistance Conferring Mutations in the rpoB Gene of Mycobacterium tuberculosis: Mapping the Potential of Pharmaco-metabolomics for Global Health and Personalized Medicine.
Tuberculosis
Analysis of RNA polymerase gene mutation in three isolates of rifampicin resistant Mycobacterium tuberculosis.
Tuberculosis
Antimicrobial agent resistance in mycobacteria: molecular genetic insights.
Tuberculosis
Association of ? with the C-Terminal Region of the ?' Subunit Is Essential for Assembly of RNA Polymerase in Mycobacterium tuberculosis.
Tuberculosis
Bifidobacterium adolescentis is intrinsically resistant to antitubercular drugs.
Tuberculosis
CarD and RbpA modify the kinetics of initial transcription and slow promoter escape of the Mycobacterium tuberculosis RNA polymerase.
Tuberculosis
CarD contributes to diverse gene expression outcomes throughout the genome of Mycobacterium tuberculosis.
Tuberculosis
Cascade of extracytoplasmic function sigma factors in Mycobacterium tuberculosis: identification of a sigmaJ-dependent promoter upstream of sigI.
Tuberculosis
Cell-Based High-Throughput Screening Identifies Rifapentine as an Inhibitor of Amyloid and Biofilm Formation in Escherichia coli.
Tuberculosis
Characterization by automated DNA sequencing of mutations in the gene (rpoB) encoding the RNA polymerase beta subunit in rifampin-resistant Mycobacterium tuberculosis strains from New York City and Texas.
Tuberculosis
Characterization of Mutations Conferring Resistance to Rifampin in Mycobacterium tuberculosis Clinical Strains.
Tuberculosis
Characterization of spontaneous, In vitro-selected, rifampin-resistant mutants of Mycobacterium tuberculosis strain H37Rv.
Tuberculosis
Characterization of Tunisian Mycobacterium tuberculosis rifampin-resistant clinical isolates.
Tuberculosis
Chemical cleavage of mismatches in heteroduplexes of the rpoB gene for detection of mutations associated with resistance of Mycobacterium tuberculosis to rifampin.
Tuberculosis
Clinical evaluation of a 16S ribosomal RNA polymerase chain reaction test for the diagnosis of lymph node tuberculosis.
Tuberculosis
Co-inhibition as a strategic therapeutic approach to overcome rifampin resistance in tuberculosis therapy: atomistic insights.
Tuberculosis
Comparative antimycobacterial activities of rifampin, rifapentine, and KRM-1648 against a collection of rifampin-resistant Mycobacterium tuberculosis isolates with known rpoB mutations.
Tuberculosis
Consensus numbering system for the rifampicin resistance-associated rpoB gene mutations in pathogenic mycobacteria.
Tuberculosis
Construction and characterization of a Mycobacterium tuberculosis mutant lacking the alternate sigma factor gene, sigF.
Tuberculosis
Crystal structure of Mycobacterium tuberculosis CarD, an essential RNA polymerase binding protein, reveals a quasidomain-swapped dimeric structural architecture.
Tuberculosis
Depleting Mycobacterium tuberculosis of the transcription termination factor Rho causes pervasive transcription and rapid death.
Tuberculosis
Detection of Mycobacterium tuberculosis directly from sputum by using a prototype automated Q-beta replicase assay.
Tuberculosis
Development of a novel secondary phenotypic screen to identify hits within the mycobacterial protein synthesis pipeline.
Tuberculosis
Different rifampin sensitivities of Escherichia coli and Mycobacterium tuberculosis RNA polymerases are not explained by the difference in the beta-subunit rifampin regions I and II.
Tuberculosis
Differential identification of Mycobacterium tuberculosis complex and nontuberculous mycobacteria by duplex PCR assay using the RNA polymerase gene (rpoB).
Tuberculosis
Direct genotypic detection of Mycobacterium tuberculosis rifampin resistance in clinical specimens by using single-tube heminested PCR.
Tuberculosis
Discovery of a capuramycin analog that kills nonreplicating Mycobacterium tuberculosis and its synergistic effects with translocase I inhibitors.
Tuberculosis
Distinct and Contrasting Transcription Initiation Patterns at Mycobacterium tuberculosis Promoters.
Tuberculosis
Distinct Mechanism Evolved for Mycobacterial RNA Polymerase and Topoisomerase I Protein-Protein Interaction.
Tuberculosis
Effects of Increasing the Affinity of CarD for RNA Polymerase on Mycobacterium tuberculosis Growth, rRNA Transcription, and Virulence.
Tuberculosis
Enhanced immunogenicity to Mycobacterium tuberculosis by vaccination with an alphavirus plasmid replicon expressing antigen 85A.
Tuberculosis
Essentiality of DevR/DosR interaction with SigA for the dormancy survival program in Mycobacterium tuberculosis.
Tuberculosis
Evaluation of the INNO-LiPA Rif. TB assay, a reverse hybridization assay for the simultaneous detection of Mycobacterium tuberculosis complex and its resistance to rifampin.
Tuberculosis
Evolutionary comparison of ribosomal operon antitermination function.
Tuberculosis
Fitness costs of rifampicin resistance in Mycobacterium tuberculosis are amplified under conditions of nutrient starvation and compensated by mutation in the ?' subunit of RNA polymerase.
Tuberculosis
Fitness-compensatory mutations in rifampicin-resistant RNA polymerase.
Tuberculosis
Functional insights into Mycobacterium tuberculosis DevR-dependent transcriptional machinery utilizing Escherichia coli.
Tuberculosis
Genome-wide Definition of the SigF Regulon in Mycobacterium tuberculosis.
Tuberculosis
Genome-Wide Mapping of the Distribution of CarD, RNAP ?(A), and RNAP ? on the Mycobacterium smegmatis Chromosome using Chromatin Immunoprecipitation Sequencing.
Tuberculosis
High-resolution transcriptome and genome-wide dynamics of RNA polymerase and NusA in Mycobacterium tuberculosis.
Tuberculosis
Homology modeling of wild-type, D516V, and H526L Mycobacterium tuberculosis RNA polymerase and their molecular docking study with inhibitors.
Tuberculosis
Identification and characterization of pleiotropic high-persistence mutations in the beta subunit of the bacterial RNA polymerase.
Tuberculosis
Identification and characterization of the dps promoter of Mycobacterium smegmatis: promoter recognition by stress-specific extracytoplasmic function sigma factors sigmaH and sigmaF.
Tuberculosis
Identification of mutations in the rpoB encoding the RNA polymerase beta subunit in rifampicine-resistant Mycobacterium tuberculosis strains from Iran.
Tuberculosis
Identification of new antibacterial targets in RNA polymerase of Mycobacterium tuberculosis by detecting positive selection sites.
Tuberculosis
Identification of promoters recognized by RNA polymerase containing Mycobacterium tuberculosis stress-response sigma factor sigma(F).
Tuberculosis
Implication from the predicted docked interaction of sigma H and exploration of its interaction with RNA polymerase in Mycobacterium tuberculosis.
Tuberculosis
Inhibition of Mycobacterium tuberculosis RNA polymerase by binding of a Gre factor homolog to the secondary channel.
Tuberculosis
Isolation of the gene for the beta subunit of RNA polymerase from rifampicin-resistant Mycobacterium tuberculosis and identification of new mutations.
Tuberculosis
Lipiarmycin targets RNA polymerase and has good activity against multidrug-resistant strains of Mycobacterium tuberculosis.
Tuberculosis
Lost in transcription--inhibition of RNA polymerase.
Tuberculosis
Mechanistic Principles Behind Molecular Mechanism of Rifampicin Resistance in Mutant RNA Polymerase Beta Subunit of Mycobacterium tuberculosis.
Tuberculosis
Molecular characterization of mutation associated with rifampicin and isoniazid resistance in Mycobacterium tuberculosis isolates.
Tuberculosis
Molecular mechanisms of drug resistance in Mycobacterium tuberculosis clinical isolates.
Tuberculosis
Multidrug-resistant Mycobacterium tuberculosis: molecular perspectives.
Tuberculosis
Mutation Analysis of Mycobacterial rpoB Genes and Rifampicin Resistance Using Recombinant Mycobacterium smegmatis.
Tuberculosis
Mutation position and type of substitution in the beta-subunit of the RNA polymerase influence in-vitro activity of rifamycins in rifampicin-resistant Mycobacterium tuberculosis.
Tuberculosis
Mutational Frequencies in Mycobacterial rpoB gene using GeneXpert/MTB Rif Assay in Rifampicin Resistant patients at a tertiary care setting in Urban Sindh, Pakistan: Analysis from a Five-Year Period.
Tuberculosis
Mutations in rpoB gene of rifampicin resistant clinical isolates of Mycobacterium tuberculosis in Japan.
Tuberculosis
Mutations of rpob Gene Associated with Rifampin Resistance among Mycobacterium Tuberculosis Isolated in Tuberculosis Regional Reference Laboratory in Northeast of Iran during 2015-2016.
Tuberculosis
Mycobacterium RbpA cooperates with the stress-response ?B subunit of RNA polymerase in promoter DNA unwinding.
Tuberculosis
Mycobacterium tuberculosis CarD, an essential global transcriptional regulator forms amyloid-like fibrils.
Tuberculosis
Mycobacterium tuberculosis ECF sigma factor sigC is required for lethality in mice and for the conditional expression of a defined gene set.
Tuberculosis
Mycobacterium tuberculosis RbpA protein is a new type of transcriptional activator that stabilizes the ?A-containing RNA polymerase holoenzyme.
Tuberculosis
Mycobacterium tuberculosis RNA polymerase-binding protein A (RbpA) and its interactions with sigma factors.
Tuberculosis
Mycobacterium tuberculosis Rv1474c is a TetR-like transcriptional repressor that regulates aconitase, an essential enzyme and RNA-binding protein, in an iron-responsive manner.
Tuberculosis
Novel mechanism of gene regulation: the protein Rv1222 of Mycobacterium tuberculosis inhibits transcription by anchoring the RNA polymerase onto DNA.
Tuberculosis
Optimization of a two-plasmid system for the identification of promoters recognized by RNA polymerase containing Mycobacterium tuberculosis stress response sigma factor, sigmaF.
Tuberculosis
Optimization of recombinant Mycobacterium tuberculosis RNA polymerase expression and purification.
Tuberculosis
Performance of an automated Q-beta replicase amplification assay for Mycobacterium tuberculosis in a clinical trial.
Tuberculosis
Probing the Molecular Mechanism of Rifampin Resistance Caused by the Point Mutations S456L and D441V on Mycobacterium tuberculosis RNA Polymerase through Gaussian Accelerated Molecular Dynamics Simulation.
Tuberculosis
Production and characterization of a highly pure RNA polymerase holoenzyme from Mycobacterium tuberculosis.
Tuberculosis
Prospective evaluation of the utility of molecular techniques for diagnosing nosocomial transmission of multidrug-resistant tuberculosis.
Tuberculosis
Pulmonary tuberculosis in the West Bank, Palestinian Authority: molecular diagnostic approach.
Tuberculosis
Purification and properties of DNA-dependent RNA polymerase from Mycobacterium tuberculosis H37RV.
Tuberculosis
Q-beta replicase-amplified assay for detection of Mycobacterium tuberculosis directly from clinical specimens.
Tuberculosis
Rapid detection of mutations in rpoB gene of rifampicin resistant Mycobacterium tuberculosis strains by line probe assay.
Tuberculosis
Rapid detection of rpoB gene mutations conferring rifampin resistance in Mycobacterium tuberculosis.
Tuberculosis
RbpA relaxes promoter selectivity of M. tuberculosis RNA polymerase.
Tuberculosis
Recombinant reporter assay using transcriptional machinery of Mycobacterium tuberculosis.
Tuberculosis
Resistance profiles and rpoB gene mutations of Mycobacterium tuberculosis isolates in Taiwan.
Tuberculosis
Restriction endonuclease analysis as a solution for determining rifampin resistance mutations by automated DNA sequencing in heteroresistant Mycobacterium tuberculosis strains.
Tuberculosis
Rifampin induces hydroxyl radical formation in Mycobacterium tuberculosis.
Tuberculosis
Rifampin-resistance-associated mutations in the rifampin-resistance-determining region of the rpoB gene of Mycobacterium tuberculosis clinical isolates in Shanghai, PR China.
Tuberculosis
Rifamycin action on RNA polymerase in antibiotic-tolerant Mycobacterium tuberculosis results in differentially detectable populations.
Tuberculosis
Robust Strand Exchange Reactions for the Sequence-Specific, Real-Time Detection of Nucleic Acid Amplicons.
Tuberculosis
Role of 5'-TGN-3' motif in the interaction of mycobacterial RNA polymerase with a promoter of 'extended -10' class.
Tuberculosis
Role of an RNA polymerase interacting protein, MsRbpA, from Mycobacterium smegmatis in phenotypic tolerance to rifampicin.
Tuberculosis
Routine rapid Mycobacterium species assignment based on species-specific allelic variation in the 65-kilodalton heat shock protein gene (hsp65).
Tuberculosis
Rv0474 is a copper-responsive transcriptional regulator that negatively regulates expression of RNA polymerase ? subunit in Mycobacterium tuberculosis.
Tuberculosis
Screening of African medicinal plants for antimicrobial and enzyme inhibitory activity.
Tuberculosis
Sigma factor F does not prevent rifampin inhibition of RNA polymerase or cause rifampin tolerance in Mycobacterium tuberculosis.
Tuberculosis
Simultaneous identification of rifampin-resistant Mycobacterium tuberculosis and nontuberculous mycobacteria by polymerase chain reaction-single strand conformation polymorphism and sequence analysis of the RNA polymerase gene (rpoB).
Tuberculosis
Source of the Fitness Defect in Rifamycin-Resistant Mycobacterium tuberculosis RNA Polymerase and the Mechanism of Compensation by Mutations in the ?' Subunit.
Tuberculosis
Structural analysis of sigma E interactions with core RNA polymerase and its cognate P-hsp20 promoter of Mycobacterium tuberculosis.
Tuberculosis
Structural basis for rifamycin resistance of bacterial RNA polymerase by the three most clinically important RpoB mutations found in Mycobacterium tuberculosis.
Tuberculosis
Structural basis of ECF-?-factor-dependent transcription initiation.
Tuberculosis
Structural basis of transcriptional activation by the Mycobacterium tuberculosis intrinsic antibiotic-resistance transcription factor WhiB7.
Tuberculosis
Structural Implications of Mutations Conferring Rifampin Resistance in Mycobacterium leprae.
Tuberculosis
Structural insights into the functional divergence of WhiB-like proteins in Mycobacterium tuberculosis.
Tuberculosis
Structural insights into the mycobacteria transcription initiation complex from analysis of X-ray crystal structures.
Tuberculosis
Structure and function of CarD, an essential mycobacterial transcription factor.
Tuberculosis
Structure of the carboxy-terminal domain of Mycobacterium tuberculosis CarD protein: an essential rRNA transcriptional regulator.
Tuberculosis
Structures of the Catalytic Domain of Bacterial Primase DnaG in Complexes with DNA Provide Insight into Key Priming Events.
Tuberculosis
Study of Genetic Evolution in Mycobacterium tuberculosis Isolates from Patients with Active Pulmonary Tuberculosis in the Iran and Belarus.
Tuberculosis
Synergistic Interplay of The Co-administration of Rifampin And Newly Developed Anti-TB Drug: Could It Be a Promising New Line of TB Therapy?
Tuberculosis
The actinobacterial transcription factor RbpA binds to the principal sigma subunit of RNA polymerase.
Tuberculosis
The Enzymes of the Rifamycin Antibiotic Resistome.
Tuberculosis
The EU approved antimalarial pyronaridine shows antitubercular activity and synergy with rifampicin, targeting RNA polymerase.
Tuberculosis
The rpoB gene of Mycobacterium tuberculosis.
Tuberculosis
Transcription of two sigma 70 homologue genes, sigA and sigB, in stationary-phase Mycobacterium tuberculosis.
Tuberculosis
Uncovering the Resistance Mechanism of Mycobacterium tuberculosis to Rifampicin Due to RNA Polymerase H451D/Y/R Mutations From Computational Perspective.
Tuberculosis
Use of DNA extracts from Ziehl-Neelsen-stained slides for molecular detection of rifampin resistance and spoligotyping of Mycobacterium tuberculosis.
Tuberculosis
Whole-genome sequencing of rifampicin-resistant Mycobacterium tuberculosis strains identifies compensatory mutations in RNA polymerase genes.
Tuberculosis
[New inhibitors targeting bacterial RNA polymerase].
Tuberculosis
[Studies on mutation of rifampicin-resistant genes in M. tuberculosis]
Tuberculosis, Lymph Node
Clinical evaluation of a 16S ribosomal RNA polymerase chain reaction test for the diagnosis of lymph node tuberculosis.
Tuberculosis, Multidrug-Resistant
Combining COLD-PCR and high-resolution melt analysis for rapid detection of low-level, rifampin-resistant mutations in Mycobacterium tuberculosis.
Tuberculosis, Multidrug-Resistant
Fitness costs of rifampicin resistance in Mycobacterium tuberculosis are amplified under conditions of nutrient starvation and compensated by mutation in the ?' subunit of RNA polymerase.
Tumor Virus Infections
RNA polymerase in cells infected with Shope fibroma virus.
Typhus, Epidemic Louse-Borne
Characterization of mutations in the rpoB gene in naturally rifampin-resistant Rickettsia species.
Urinary Bladder Neoplasms
Knockdown of mediator subunit Med19 suppresses bladder cancer cell proliferation and migration by downregulating Wnt/?-catenin signalling pathway.
Urinary Bladder Neoplasms
Long non-coding RNA urothelial carcinoma associated 1 induces cell replication by inhibiting BRG1 in 5637 cells.
Urinary Bladder Neoplasms
Re: Yves Allorya, Willemien Beukers, Ana Sagrera, et al. Telomerase Reverse Transcriptase Promoter Mutations in Bladder Cancer: High Frequency Across Stages, Detection in Urine, and Lack of Association with Outcome. Eur Urol 2014;65:360-6: Telomerase Expression and Stem Cells: Urologic Epithelial Perspective.
Urinary Bladder Neoplasms
RNA-binding protein HuR promotes bladder cancer progression by competitively binding to the long noncoding HOTAIR with miR-1.
Uterine Cervical Neoplasms
Msi1 promotes tumor growth and cell proliferation by targeting cell cycle checkpoint proteins p21, p27 and p53 in cervical carcinomas.
Uterine Cervical Neoplasms
Musashi-2, a novel oncoprotein promoting cervical cancer cell growth and invasion, is negatively regulated by p53-induced miR-143 and miR-107 activation.
Vaccinia
A cellular factor is required for transcription of vaccinia viral intermediate-stage genes.
Vaccinia
A cellular protein binds vaccinia virus late promoters and activates transcription in vitro.
Vaccinia
A freeze-frame view of eukaryotic transcription during elongation and capping of nascent mRNA.
Vaccinia
A macrophage fusion assay for rapid screening of cloned HIV-1 Env using dual recombinant vaccinia viruses expressing distinct RNA polymerases.
Vaccinia
A myxoma virus nucleotide sequence with homology to the vaccinia virus RNA polymerase 22-kDa subunit gene.
Vaccinia
A potential role for the nucleolus in L1 retrotransposition.
Vaccinia
A role for ATP hydrolysis in vaccinia virus early gene transcription. Dissociation of the early transcription factor-promoter complex.
Vaccinia
A role for the H4 subunit of vaccinia RNA polymerase in transcription initiation at a viral early promoter.
Vaccinia
A vaccinia virus isatin-beta-thiosemicarbazone resistance mutation maps in the viral gene encoding the 132-kDa subunit of RNA polymerase.
Vaccinia
Adenosine N1-oxide inhibits vaccinia virus replication by blocking translation of viral early mRNAs.
Vaccinia
An ATPase component of the transcription elongation complex is required for factor-dependent transcription termination by vaccinia RNA polymerase.
Vaccinia
An isatin-beta-thiosemicarbazone-resistant vaccinia virus containing a mutation in the second largest subunit of the viral RNA polymerase is defective in transcription elongation.
Vaccinia
Analysis of murine major histocompatibility complex class II-restricted T-cell responses to the flavivirus Kunjin by using vaccinia virus expression.
Vaccinia
Analysis of respiratory syncytial virus F, G, and SH proteins in cell fusion.
Vaccinia
Antibodies directed against an epitope in the N-terminal region of the H4L subunit of the vaccinia virus RNA polymerase inhibit both transcription initiation and transcription termination, in vitro.
Vaccinia
Antitermination of vaccinia virus early transcription: possible role of RNA secondary structure.
Vaccinia
Baculovirus-expressed nonstructural protein NS2 of bluetongue virus induces a cytotoxic T-cell response in mice which affords partial protection.
Vaccinia
Biochemical and electron microscopic studies of the transcription of vaccinia DNA by RNA polymerase from Escherichia coli: localization and characterization of transcriptional complexes.
Vaccinia
Bromouridine triphosphate inhibits transcription termination and mRNA release by vaccinia virions.
Vaccinia
Cascade regulation of vaccinia virus gene expression is modulated by multistage promoters.
Vaccinia
CD8 T Cell Responses to an Immunodominant Epitope within the Nonstructural Protein NS1 Provide Wide Immunoprotection against Bluetongue Virus in IFNAR-/- Mice.
Vaccinia
Cells that express all five proteins of vesicular stomatitis virus from cloned cDNAs support replication, assembly, and budding of defective interfering particles.
Vaccinia
Cellular expression of a functional nodavirus RNA replicon from vaccinia virus vectors.
Vaccinia
Characterization of a vaccinia virus-encoded double-stranded RNA-binding protein that may be involved in inhibition of the double-stranded RNA-dependent protein kinase.
Vaccinia
Codon usage-mediated inhibition of HIV-1 gag expression in mammalian cells occurs independently of translation.
Vaccinia
Complementation of vaccinia virus lacking the double-stranded RNA-binding protein gene E3L by human cytomegalovirus.
Vaccinia
Cross-protective immune responses against African horse sickness virus after vaccination with protein NS1 delivered by avian reovirus muNS microspheres and modified vaccinia virus Ankara.
Vaccinia
Defective point mutants of the encephalomyocarditis virus internal ribosome entry site can be complemented in trans.
Vaccinia
Detailed phenotypic characterization of five temperature-sensitive mutants in the 22- and 147-kilodalton subunits of vaccinia virus DNA-dependent RNA polymerase.
Vaccinia
Detection of RNA-protein complex in vaccinia virus core in vitro transcription system.
Vaccinia
Determinants of vaccinia virus early gene transcription termination.
Vaccinia
Discovery of m(7)G-cap in eukaryotic mRNAs.
Vaccinia
Discrete functional stages of vaccinia virus early transcription during a single round of RNA synthesis in vitro.
Vaccinia
Double-stranded RNA-binding protein E3 controls translation of viral intermediate RNA, marking an essential step in the life cycle of modified vaccinia virus Ankara.
Vaccinia
Effect of rifamycin derivatives and coumermycin A1 on in vitro RNA synthesis by African swine fever virus. Brief report.
Vaccinia
Effect of selected mutations in the C-terminal region of the vaccinia virus nucleoside triphosphate phosphohydrolase I on binding to the H4L subunit of the viral RNA polymerase and early gene transcription termination in vitro.
Vaccinia
Elongation properties of vaccinia virus RNA polymerase: pausing, slippage, 3' end addition, and termination site choice.
Vaccinia
Emergence of a Viral RNA Polymerase Variant during Gene Copy Number Amplification Promotes Rapid Evolution of Vaccinia Virus.
Vaccinia
Endothelial cell DNA transfer and expression using petri dish electroporation and the nonreplicating vaccinia virus/T7 RNA polymerase hybrid system.
Vaccinia
Enhanced genetic rescue of negative-strand RNA viruses: use of an MVA-T7 RNA polymerase vector and DNA replication inhibitors.
Vaccinia
Evasion of cellular antiviral responses by human cytomegalovirus TRS1 and IRS1.
Vaccinia
Evidence for genetic relationship between RNA and DNA viruses from the sequence homology of a putative polymerase gene of bluetongue virus with that of vaccinia virus: conservation of RNA polymerase genes from diverse species.
Vaccinia
Expansion of poxvirus RNA polymerase subunits sharing homology with corresponding subunits of RNA polymerase II.
Vaccinia
Expression analysis of recombinant herpes simplex virus type 1 DNase.
Vaccinia
Expression of dengue virus structural proteins and nonstructural protein NS1 by a recombinant vaccinia virus.
Vaccinia
Expression of poliovirus P3 proteins using a recombinant vaccinia virus results in proteolytically active 3CD precursor protein without further processing to 3Cpro and 3Dpol.
Vaccinia
Expression strategy of the M genome segment of Hantaan virus.
Vaccinia
Factor-dependent release of nascent RNA by ternary complexes of vaccinia RNA polymerase.
Vaccinia
Factor-dependent transcription termination by vaccinia RNA polymerase. Kinetic coupling and requirement for ATP hydrolysis.
Vaccinia
Factor-dependent transcription termination by vaccinia virus RNA polymerase. Evidence that the cis-acting termination signal is in nascent RNA.
Vaccinia
Failure of poxvirus replication in the presence of an inhibitor of nucleolar RNA synthesis.
Vaccinia
Feline calicivirus capsid protein expression and self-assembly in cultured feline cells.
Vaccinia
Fine structure mapping and phenotypic analysis of five temperature-sensitive mutations in the second largest subunit of vaccinia virus DNA-dependent RNA polymerase.
Vaccinia
Fine structure mapping of five temperature-sensitive mutants in the 22- and 147-kilodalton subunits of vaccinia virus DNA-dependent RNA polymerase.
Vaccinia
Functional expression of p64, an intracellular chloride channel protein.
Vaccinia
Gene expression using the vaccinia virus/ T7 RNA polymerase hybrid system.
Vaccinia
Gene expression using the vaccinia virus/T7 RNA polymerase hybrid system.
Vaccinia
Generation of reovirus core-like particles in cells infected with hybrid vaccinia viruses that express genome segments L1, L2, L3, and S2.
Vaccinia
High expression of human chorionic gonadotrophin beta-subunit using a synthetic vaccinia virus promoter.
Vaccinia
High level transient expression of the murine coronavirus haemagglutinin-esterase.
Vaccinia
Histidine codons appended to the gene encoding the RPO22 subunit of vaccinia virus RNA polymerase facilitate the isolation and purification of functional enzyme and associated proteins from virus-infected cells.
Vaccinia
Homology between RNA polymerases of poxviruses, prokaryotes, and eukaryotes: nucleotide sequence and transcriptional analysis of vaccinia virus genes encoding 147-kDa and 22-kDa subunits.
Vaccinia
Human cytomegalovirus-specific cytotoxic T cells. Relative frequency of stage-specific CTL recognizing the 72-kD immediate early protein and glycoprotein B expressed by recombinant vaccinia viruses.
Vaccinia
Human immunodeficiency virus type 1 Vpu protein induces degradation of chimeric envelope glycoproteins bearing the cytoplasmic and anchor domains of CD4: role of the cytoplasmic domain in Vpu-induced degradation in the endoplasmic reticulum.
Vaccinia
Hydrolytic cleavage of nascent RNA in RNA polymerase III ternary transcription complexes.
Vaccinia
Identification and cloning of the fowlpox virus thymidine kinase gene using vaccinia virus.
Vaccinia
Identification of a transcription factor, encoded by two vaccinia virus early genes, that regulates the intermediate stage of viral gene expression.
Vaccinia
Identification of rpo30, a vaccinia virus RNA polymerase gene with structural similarity to a eucaryotic transcription elongation factor.
Vaccinia
Identification of the vaccinia virus gene encoding an 18-kilodalton subunit of RNA polymerase and demonstration of a 5' poly(A) leader on its early transcript.
Vaccinia
Identification of three H-2K(d) restricted CTL epitopes of NS4A and NS4B protein from Yellow fever 17D vaccine.
Vaccinia
Identification of vaccinia promoters by heterologous expression of hepatitis B surface antigen in mouse cells infected by recombinant vaccinia viruses.
Vaccinia
Identification, sequence, and expression of the gene encoding the second-largest subunit of the vaccinia virus DNA-dependent RNA polymerase.
Vaccinia
Immunization of mice with recombinant vaccinia virus expressing authentic dengue virus nonstructural protein NS1 protects against lethal dengue virus encephalitis.
Vaccinia
In vitro transcription of a cloned vaccinia virus gene by a soluble extract prepared from vaccinia virus-infected HeLa cells.
Vaccinia
Inefficient complementation activity of poliovirus 2C and 3D proteins for rescue of lethal mutations.
Vaccinia
Inhibition of the RNA polymerase III-mediated dsDNA-sensing pathway of innate immunity by vaccinia virus protein E3.
Vaccinia
Interaction between nucleoside triphosphate phosphohydrolase I and the H4L subunit of the viral RNA polymerase is required for vaccinia virus early gene transcript release.
Vaccinia
Interaction between the J3R subunit of vaccinia virus poly(A) polymerase and the H4L subunit of the viral RNA polymerase.
Vaccinia
Interaction of the vaccinia virus RNA polymerase-associated protein of 94-kDa with the early transcription factor.
Vaccinia
La Crosse virus nonstructural protein NSs counteracts the effects of short interfering RNA.
Vaccinia
Localization of mouse hepatitis virus open reading frame 1A derived proteins.
Vaccinia
Localization of the Vpx packaging signal within the C terminus of the human immunodeficiency virus type 2 Gag precursor protein.
Vaccinia
M2 Macrophages Play Critical Roles in Progression of Inflammatory Liver Disease in Hepatitis C Virus Transgenic Mice.
Vaccinia
Mapping and phenotypic analysis of spontaneous isatin-beta-thiosemicarbazone resistant mutants of vaccinia virus.
Vaccinia
Mapping the interacting domains between the rabies virus polymerase and phosphoprotein.
Vaccinia
Mechanisms of replication-deficient vaccinia virus/T7 RNA polymerase hybrid expression: effect of T7 RNA polymerase levels and alpha-amanitin.
Vaccinia
Membrane permeabilization by poliovirus proteins 2B and 2BC.
Vaccinia
Membrane-associated respiratory syncytial virus F protein expressed from a human rhinovirus type 14 vector is immunogenic.
Vaccinia
Mice immunized with recombinant vaccinia virus expressing dengue 4 virus structural proteins with or without nonstructural protein NS1 are protected against fatal dengue virus encephalitis.
Vaccinia
Mutagen activation by cDNA-expressed P(1)450, P(3)450, and P450a.
Vaccinia
Mutational analysis identifies functional domains in the influenza A virus PB2 polymerase subunit.
Vaccinia
Mutations in the DI-DII Linker of Human Parainfluenza Virus Type 3 Fusion Protein Result in Diminished Fusion Activity.
Vaccinia
Mutations in the Leucine Zipper-Like Motif of the Human Parainfluenza Virus 3 Fusion Protein Impair Fusion Activity.
Vaccinia
Nascent RNA cleavage by purified ternary complexes of vaccinia RNA polymerase.
Vaccinia
Nuclear localization of a double-stranded RNA-binding protein encoded by the vaccinia virus E3L gene.
Vaccinia
Ordered assembly of a functional preinitiation transcription complex, containing vaccinia virus early transcription factor and RNA polymerase, on an immobilized template.
Vaccinia
Overexpression, purification, and late transcription factor activity of the 17-kilodalton protein encoded by the vaccinia virus A1L gene.
Vaccinia
Phenotypic characterization of mutants in vaccinia virus gene G2R, a putative transcription elongation factor.
Vaccinia
Physical and functional characterization of the double-stranded RNA binding protein encoded by the vaccinia virus E3 gene.
Vaccinia
Polyamines stimulate DNA-dependent RNA synthesis catalyzed by vaccinia virus.
Vaccinia
Process of cap formation of messenger RNA by vaccinia virus particles carrying an organized enzymes system.
Vaccinia
Production of HIV-1 gp120 in packed-bed bioreactor using the vaccinia virus/T7 expression system.
Vaccinia
Promoter DNA contacts made by the vaccinia virus early transcription factor.
Vaccinia
Promoter melting by a stage-specific vaccinia virus transcription factor is independent of the presence of RNA polymerase.
Vaccinia
Proteolytic processing of the porcine reproductive and respiratory syndrome virus replicase.
Vaccinia
Purification and identification of a vaccinia virus-encoded intermediate stage promoter-specific transcription factor that has homology to eukaryotic transcription factor SII (TFIIS) and an additional role as a viral RNA polymerase subunit.
Vaccinia
Purification of the late transcription system of vaccinia virus: identification of a novel transcription factor.
Vaccinia
Recovery of NV knockout infectious hematopoietic necrosis virus expressing foreign genes.
Vaccinia
Recruitment of vaccinia virus RNA polymerase to an early gene promoter by the viral early transcription factor.
Vaccinia
Regions on the hemagglutinin-neuraminidase proteins of human parainfluenza virus type-1 and Sendai virus important for membrane fusion.
Vaccinia
Regulated expression of nuclear genes by T3 RNA polymerase and lac repressor, using recombinant vaccinia virus vectors.
Vaccinia
Relationship between RNA polymerase II and efficiency of vaccinia virus replication.
Vaccinia
Replication and amplification of defective interfering particle RNAs of vesicular stomatitis virus in cells expressing viral proteins from vectors containing cloned cDNAs.
Vaccinia
Replication of hepatitis A viruses with chimeric 5' nontranslated regions.
Vaccinia
Requirements for the self-directed replication of flock house virus RNA 1.
Vaccinia
Reverse Genetics System for the Avian Coronavirus Infectious Bronchitis Virus.
Vaccinia
RNA polymerase activity in purified infectious vaccinia virus.
Vaccinia
RNA polymerase III and antiviral innate immune response.
Vaccinia
RNA Polymerase Mutations Selected during Experimental Evolution Enhance Replication of a Hybrid Vaccinia Virus with an Intermediate Transcription Factor Subunit Replaced by the Myxoma Virus Ortholog.
Vaccinia
RNA polymerase-associated protein Rap94 confers promoter specificity for initiating transcription of vaccinia virus early stage genes.
Vaccinia
RNA polymerase-associated transcription specificity factor encoded by vaccinia virus.
Vaccinia
Role of forward translocation in nucleoside triphosphate phosphohydrolase I (NPH I)-mediated transcription termination of vaccinia virus early genes.
Vaccinia
Sedimentation of an RNA polymerase complex from vaccinia virus that specifically initiates and terminates transcription.
Vaccinia
Similarity in genome organization between Molluscum contagiosum virus (MCV) and vaccinia virus (VV): identification of MCV homologues of the VV genes for protein kinase 2, structural protein VP8, RNA polymerase 35 kDa subunit and 3beta-hydroxysteroid dehydrogenase.
Vaccinia
Site-specific mutations in vectors that express antigenic and temperature-sensitive phenotypes of the M gene of vesicular stomatitis virus.
Vaccinia
Site-specific RNA cleavage generates the 3' end of a poxvirus late mRNA.
Vaccinia
Some enzymatic activities associated with purified parapoxvirions.
Vaccinia
SP6 RNA polymerase containing vaccinia virus for rapid expression of cloned genes in tissue culture.
Vaccinia
Specific initiation of replication at the right-end telomere of the closed species of minute virus of mice replicative-form DNA.
Vaccinia
Stability of ternary transcription complexes of vaccinia virus RNA polymerase at promoter-proximal positions.
Vaccinia
Stringent chemical and thermal regulation of recombinant gene expression by vaccinia virus vectors in mammalian cells.
Vaccinia
Structural analysis of ternary complexes of vaccinia RNA polymerase.
Vaccinia
Structural Basis of Poxvirus Transcription: Vaccinia RNA Polymerase Complexes.
Vaccinia
Studies on RNA polymerase inhibitor formed in virus-infected cells. 3. Induction of inhibitor of cellular nucleic acid synthesis in vaccinia virus-infected cells.
Vaccinia
Synthesis of biologically active influenza virus core proteins using a vaccinia virus-T7 RNA polymerase expression system.
Vaccinia
Targeting of a multicomponent transcription apparatus into assembling vaccinia virus particles requires RAP94, an RNA polymerase-associated protein.
Vaccinia
Temperature-sensitive mutations in the vaccinia virus H4 gene encoding a component of the virion RNA polymerase.
Vaccinia
Ternary complex formation by vaccinia virus RNA polymerase at an early viral promoter: analysis by native gel electrophoresis.
Vaccinia
The D1 and D12 subunits are both essential for the transcription termination factor activity of vaccinia virus capping enzyme.
Vaccinia
The DI-DII linker of human parainfluenza virus type 3 fusion protein is critical for the virus.
Vaccinia
The DNA-dependent ATPase activity of vaccinia virus early gene transcription factor is essential for its transcription activation function.
Vaccinia
The E3L gene of vaccinia virus encodes an inhibitor of the interferon-induced, double-stranded RNA-dependent protein kinase.
Vaccinia
The E7 oncoprotein of human papillomavirus type 16 interacts with F-actin in vitro and in vivo.
Vaccinia
The gene (POLR2L) encoding the hRPB7.6 subunit of human RNA polymerase.
Vaccinia
The H4 subunit of vaccinia virus RNA polymerase is not required for transcription initiation at a viral late promoter.
Vaccinia
The L protein of Rift Valley fever virus can rescue viral ribonucleoproteins and transcribe synthetic genome-like RNA molecules.
Vaccinia
The late expression factors 8 and 9 and possibly the phosphoprotein p78/83 of Autographa californica multicapsid nucleopolyhedrovirus are components of the virus-induced RNA polymerase.
Vaccinia
The role of vaccinia termination factor and cis-acting elements in vaccinia virus early gene transcription termination.
Vaccinia
The small subunit of the vaccinia virus early transcription factor contacts the transcription promoter DNA.
Vaccinia
The viral RNA polymerase H4L subunit is required for Vaccinia virus early gene transcription termination.
Vaccinia
Tn9 CAT gene contains a promoter for vaccinia virus transcription: implications for reverse-genetic techniques.
Vaccinia
trans complementation of cap-independent translation directed by poliovirus 5' noncoding region deletion mutants: evidence for RNA-RNA interactions.
Vaccinia
Transcription termination by vaccinia RNA polymerase entails recognition of specific phosphates in the nascent RNA.
Vaccinia
Transient expression and sequence of the matrix (M1) gene of WSN influenza A virus in a vaccinia vector.
Vaccinia
Translational regulation of Na,K-ATPase alpha1 and beta1 polypeptide expression in epithelial cells.
Vaccinia
Use of a hybrid vaccinia virus-T7 RNA polymerase system for expression of target genes.
Vaccinia
Use of the Capripoxvirus homologue of Vaccinia virus 30kDa RNA polymerase subunit (RPO30) gene as a novel diagnostic and genotyping target: Development of a classical PCR method to differentiate Goat poxvirus from Sheep poxvirus.
Vaccinia
UUUUUNU oligonucleotide stimulation of vaccinia virus early gene transcription termination, in trans.
Vaccinia
Vaccinia NPH-I, a DExH-box ATPase, is the energy coupling factor for mRNA transcription termination.
Vaccinia
Vaccinia virus double-stranded RNA-binding protein E3 does not interfere with siRNA-mediated gene silencing in mammalian cells.
Vaccinia
Vaccinia virus early gene transcription termination factors VTF and Rap94 interact with the U9 termination motif in the nascent RNA in a transcription ternary complex.
Vaccinia
Vaccinia virus gene D7R encodes a 20,000-dalton subunit of the viral DNA-dependent RNA polymerase.
Vaccinia
Vaccinia virus gene encoding a 30-kilodalton subunit of the viral DNA-dependent RNA polymerase.
Vaccinia
Vaccinia virus intermediate and late promoter elements are targeted by the TATA-binding protein.
Vaccinia
Vaccinia virus intermediate stage transcription is complemented by Ras-GTPase-activating protein SH3 domain-binding protein (G3BP) and cytoplasmic activation/proliferation-associated protein (p137) individually or as a heterodimer.
Vaccinia
Vaccinia virus nonstructural protein encoded by the A11R gene is required for formation of the virion membrane.
Vaccinia
Vaccinia virus RNA polymerase associated with nuclei of infected HeLa cells.
Vaccinia
Vaccinia virus transcription.
Vaccinia
Vaccinia virus-T7 RNA polymerase expression system for neurotransmitter transporters.
Vaccinia
Varicella-zoster virus glycoprotein gpI/gpIV receptor: expression, complex formation, and antigenicity within the vaccinia virus-T7 RNA polymerase transfection system.
Vaccinia
VP1, the putative RNA-dependent RNA polymerase of infectious bursal disease virus, forms complexes with the capsid protein VP3, leading to efficient encapsidation into virus-like particles.
Vaccinia
[Expression of the gene for vaccinia virus 36K nonstructural protein in Escherichia coli and study of the protective properties of expression products]
Vaccinia
[Molecular biological study of the vaccinia virus. V. Study of the intracellular localization of the late nonstructural protein 36K]
Vaccinia
[The reverse genetics systems for human and animal RNA viruses]
Varicocele
Downregulation of cold-inducible RNA-binding protein activates mitogen-activated protein kinases and impairs spermatogenic function in mouse testes.
Vasculitis
Identification of beta-subunit of bacterial RNA-polymerase--a non-species-specific bacterial protein--as target of antibodies in primary biliary cirrhosis.
Vesicular Stomatitis
5'-terminal sequence of vesicular stomatitis virus mRNA's synthesized in vitro.
Vesicular Stomatitis
A dual-functional priming-capping loop of rhabdoviral RNA polymerases directs terminal de novo initiation and capping intermediate formation.
Vesicular Stomatitis
A freeze frame view of vesicular stomatitis virus transcription defines a minimal length of RNA for 5' processing.
Vesicular Stomatitis
A single amino acid change in the L-polymerase protein of vesicular stomatitis virus completely abolishes viral mRNA cap methylation.
Vesicular Stomatitis
Absence of transcriptase activity or transcription-inhibiting ability in defective interfering particles of vesicular stomatitis virus.
Vesicular Stomatitis
Activation of the virion-associated RNA polymerase of vesicular stomatitis virus by melittin.
Vesicular Stomatitis
Altered ATP function of a vesicular stomatitis virus mutant detected by kinetic analysis of the transcriptase using phosphorylated ribavirin.
Vesicular Stomatitis
An In Vitro RNA Synthesis Assay for Rabies Virus Defines Ribonucleoprotein Interactions Critical for Polymerase Activity.
Vesicular Stomatitis
Analysis of in vitro transcription products of intracellular vesicular stomatitis virus RNA polymerase.
Vesicular Stomatitis
Biochemical Characterization of Respiratory Syncytial Virus RNA-Dependent RNA Polymerase Complex.
Vesicular Stomatitis
Capping of vesicular stomatitis virus pre-mRNA is required for accurate selection of transcription stop-start sites and virus propagation.
Vesicular Stomatitis
Characterization of the phosphorylated small enzyme subunit, NS, of the vesicular stomatitis virus RNA polymerase.
Vesicular Stomatitis
Characterization of vesicular stomatitis virus mRNA species synthesized in vitro.
Vesicular Stomatitis
Complementary Mutations in the N and L Proteins for Restoration of Viral RNA Synthesis.
Vesicular Stomatitis
Complete transcription by the transcriptase of vesicular stomatitis virus.
Vesicular Stomatitis
Coupled in vitro transcription and translation of vesicular stomatitis virus messenger RNA.
Vesicular Stomatitis
Determinants of serotype specificity in transcription of vesicular stomatitis virus synthetic nucleocapsids.
Vesicular Stomatitis
Differential inhibition of vesicular stomatitis virus polypeptide synthesis by hypertonic initiation block.
Vesicular Stomatitis
Display of disparate transcription phenotype by the phosphorylation negative P protein mutants of vesicular stomatitis virus, Indiana serotype, expressed in E. coli and eucaryotic cells.
Vesicular Stomatitis
Dissociation and reconstitution of the transcriptase and template activities of vesicular stomatitis B and T virions.
Vesicular Stomatitis
Dissociation of vesicular stomatitis virus and relation of the virion proteins to the viral transcriptase.
Vesicular Stomatitis
Effect of temperature-sensitive mutation on activity of the RNA transcriptase of vesicular stomatitis virus New Jersey.
Vesicular Stomatitis
Effect of temperature-sensitive mutations on the virion-associated RNA transcriptase of vesicular stomatitis virus.
Vesicular Stomatitis
Efficient Production of Human Norovirus-Specific IgY in Egg Yolks by Vaccination of Hens with a Recombinant Vesicular Stomatitis Virus Expressing VP1 Protein.
Vesicular Stomatitis
Expression of a cDNA encoding a functional 241-kilodalton vesicular stomatitis virus RNA polymerase.
Vesicular Stomatitis
Expression of L protein of vesicular stomatitis virus Indiana serotype from recombinant baculovirus in insect cells: requirement of a host factor(s) for its biological activity in vitro.
Vesicular Stomatitis
Faithful and efficient in vitro reconstitution of vesicular stomatitis virus transcription using plasmid-encoded L and P proteins.
Vesicular Stomatitis
Formation of guanosine(5')tetraphospho(5')adenosine cap structure by an unconventional mRNA capping enzyme of vesicular stomatitis virus.
Vesicular Stomatitis
Function and structure of RNA polymerase from vesicular stomatitis virus.
Vesicular Stomatitis
Histidine-mediated RNA transfer to GDP for unique mRNA capping by vesicular stomatitis virus RNA polymerase.
Vesicular Stomatitis
Host range mutants of vesicular stomatitis virus defective in in vitro RNA methylation.
Vesicular Stomatitis
Identification of a domain within the phosphoprotein of vesicular stomatitis virus that is essential for transcription in vitro.
Vesicular Stomatitis
Identification of a set of proteins (C' and C) encoded by the bicistronic P gene of the Indiana serotype of vesicular stomatitis virus and analysis of their effect on transcription by the viral RNA polymerase.
Vesicular Stomatitis
In vitro capping and transcription of rhabdoviruses.
Vesicular Stomatitis
In vitro inhibition of negative strand virus transcriptase activity by proteins soluble in acidic chloroform-methanol.
Vesicular Stomatitis
In vitro RNA transcription by the New Jersey serotype of vesicular stomatitis virus. I. Characterization of the mRNA species.
Vesicular Stomatitis
In vitro synthesis of genome length complementary RNA of vesicular stomatitis virus in the presence of inosine 5'-triphosphate.
Vesicular Stomatitis
In vitro synthesis of messenger RNA by a defective interfering particle of vesicular stomatitis virus.
Vesicular Stomatitis
In vitro synthesis of methylated messenger RNA by the virion-associated RNA polymerase of vesicular stomatitis virus.
Vesicular Stomatitis
In vitro synthesis of RNA that contains polyadenylate by virion-associated RNA polymerase of vesicular stomatitis virus.
Vesicular Stomatitis
In vitro synthesis of the full-length complement of the negative-strand genome RNA of vesicular stomatitis virus.
Vesicular Stomatitis
In vitro transcriptase activity of vesicular stomatitis virus B and T particles: analysis of product.
Vesicular Stomatitis
Inactivation of influenza and vesicular stomatitis virion RNA polymerase activities by photoreaction with 4'-substituted psoralens.
Vesicular Stomatitis
Inactivation of the RNA polymerase of vesicular stomatitis virus by N-ethylmaleimide and protection by nucleoside triphosphates. Evidence for a second ATP binding site on L protein.
Vesicular Stomatitis
Inhibition by aurintricarboxylic acid and polyethylene sulfonate of RNA transcription of vesicular stomatitis virus.
Vesicular Stomatitis
Inhibition of host RNA polymerase II-dependent transcription by vesicular stomatitis virus results from inactivation of TFIID.
Vesicular Stomatitis
Inhibition of the RNA polymerase of vesicular stomatitis virus by ppp5'A2'p5'A and related compounds.
Vesicular Stomatitis
Inhibition of vesicular stomatitis virus in cells constitutively expressing an antisense RNA targeted against the virus RNA polymerase gene.
Vesicular Stomatitis
Inhibition of vesicular stomatitis virus transcriptase complex by the virion envelope M protein.
Vesicular Stomatitis
Inhibition of vesicular stomatitis virus transcriptase in vitro by phosphonoformate and ara-ATP.
Vesicular Stomatitis
Inhibition of viral transcriptase by immunoglobulin directed against the nucleocapsid NS protein of vesicular stomatitis virus.
Vesicular Stomatitis
Inhibitor of vesicular stomatitis virus transcriptase in purified virions.
Vesicular Stomatitis
Initiation and direction of RNA transcription by vesicular stomatitis virus virion transcriptase.
Vesicular Stomatitis
Initiation of RNA synthesis in vitro by vesicular stomatitis virus. Role of ATP.
Vesicular Stomatitis
Interaction of L and NS proteins of vesicular stomatitis virus with its template ribonucleoprotein during RNA synthesis in vitro.
Vesicular Stomatitis
Interaction of wild-type and mutant M protein vesicular stomatitis virus with nucleocapsids in vitro.
Vesicular Stomatitis
Interferon treatment inhibits glycosylation of a viral protein.
Vesicular Stomatitis
Isolation of an infectious ribonucleoprotein from vesicular stomatitis virus containing an active RNA transcriptase.
Vesicular Stomatitis
Lack of evidence for proofreading mechanisms associated with an RNA virus polymerase.
Vesicular Stomatitis
Location of the binding domains for the RNA polymerase L and the ribonucleocapsid template within different halves of the NS phosphoprotein of vesicular stomatitis virus.
Vesicular Stomatitis
Mapping and functional role of the self-association domain of vesicular stomatitis virus phosphoprotein.
Vesicular Stomatitis
Messenger RNA species synthesized in vitro by the virion-associated RNA polymerase of vesicular stomatitis virus.
Vesicular Stomatitis
Molecular architecture of the vesicular stomatitis virus RNA polymerase.
Vesicular Stomatitis
Newly identified phosphorylation site in the vesicular stomatitis virus P protein is required for viral RNA synthesis.
Vesicular Stomatitis
NH2-terminal acidic region of the phosphoprotein of vesicular stomatitis virus can be functionally replaced by tubulin.
Vesicular Stomatitis
Norwalk virus nonstructural protein p48 forms a complex with the SNARE regulator VAP-A and prevents cell surface expression of vesicular stomatitis virus G protein.
Vesicular Stomatitis
Novel binding of GTP to the phosphoprotein (P) of vesicular stomatitis virus.
Vesicular Stomatitis
Optimal replication activity of vesicular stomatitis virus RNA polymerase requires phosphorylation of a residue(s) at carboxy-terminal domain II of its accessory subunit, phosphoprotein P.
Vesicular Stomatitis
Persistent noncytocidal vesicular stomatitis virus infections mediated by defective T particles that suppress virion transcriptase.
Vesicular Stomatitis
Phenotypic revertants of temperature-sensitive M protein mutants of vesicular stomatitis virus: sequence analysis and functional characterization.
Vesicular Stomatitis
Phosphorylation of NS protein by vesicular stomatitis virus nucleocapsids: lack of effect during RNA synthesis and separation of kinase from L protein.
Vesicular Stomatitis
Phosphorylation of specific serine residues within the acidic domain of the phosphoprotein of vesicular stomatitis virus regulates transcription in vitro.
Vesicular Stomatitis
Phosphorylation of vesicular stomatitis virus phosphoprotein P is indispensable for virus growth.
Vesicular Stomatitis
Phosphorylation within the amino-terminal acidic domain I of the phosphoprotein of vesicular stomatitis virus is required for transcription but not for replication.
Vesicular Stomatitis
Production of vesicular stomatitis virus with low infectivity by interferon-treated cells.
Vesicular Stomatitis
Promoter analysis of the vesicular stomatitis virus RNA polymerase.
Vesicular Stomatitis
Protamine--a potent inhibitor of vesicular stomatitis virus transcriptase in vitro.
Vesicular Stomatitis
Rebinding of transcriptase components (L and NS proteins) to the nucleocapsid template of vesicular stomatitis virus.
Vesicular Stomatitis
Reconstitution of infectivity and transcriptase activity of homologous and heterologous viruses: vesicular stomatitis (Indiana serotype), Chandipura, vesicular stomatitis (New Jersey serotype), and Cocal viruses.
Vesicular Stomatitis
Reconstitution studies detect a single polymerase entry site on the vesicular stomatitis virus genome.
Vesicular Stomatitis
Regulation of RNA synthesis by the genomic termini of vesicular stomatitis virus: identification of distinct sequences essential for transcription but not replication.
Vesicular Stomatitis
Replication and transcription of viral RNAs by recombinant L proteins of New Jersey serotype of vesicular stomatitis virus.
Vesicular Stomatitis
Reversal by certain polyanions of an endogenous inhibitor of the vesicular stomatitis virus-associated transcriptase.
Vesicular Stomatitis
Revertants of a mutant of vesicular stomatitis virus which has an aberrant polyadenylation activity and a temperature-sensitive transcriptase.
Vesicular Stomatitis
Rhabdoviridae. Report of the Rhabdovirus Study Group, International Committee on Taxonomy of Viruses.
Vesicular Stomatitis
Ribonucleic acid synthesis of vesicular stomatitis virus, II. An RNA polymerase in the virion.
Vesicular Stomatitis
RNA polymerase activity and poly(A) synthesizing activity in defective T particles of vesicular stomatitis virus.
Vesicular Stomatitis
RNA polymerase of vesicular stomatitis virus specifically associates with translation elongation factor-1 alphabetagamma for its activity.
Vesicular Stomatitis
RNA polymerase-associated interactions near template promoter sequences of defective interfering particles of vesicular stomatitis virus.
Vesicular Stomatitis
RNA- temperature-sensitive mutants of vesicular stomatitis virus: L-protein thermosensitivity accounts for transcriptase restriction of group I mutants.
Vesicular Stomatitis
Role of cellular casein kinase II in the function of the phosphoprotein (P) subunit of RNA polymerase of vesicular stomatitis virus.
Vesicular Stomatitis
Role of the hypervariable hinge region of phosphoprotein P of vesicular stomatitis virus in viral RNA synthesis and assembly of infectious virus particles.
Vesicular Stomatitis
Role of the membrane (M) protein in endogenous inhibition of in vitro transcription by vesicular stomatitis virus.
Vesicular Stomatitis
Sequence of a RNA templated by the 3'-OH RNA terminus of defective interfering particles of vesicular stomatitis virus.
Vesicular Stomatitis
Sequence-specific contacts between the RNA polymerase of vesicular stomatitis virus and the leader RNA gene.
Vesicular Stomatitis
Sequential phosphorylation of the phosphoprotein of vesicular stomatitis virus by cellular and viral protein kinases is essential for transcription activation.
Vesicular Stomatitis
Site of synthesis of membrane and nonmembrane proteins of vesicular stomatitis virus.
Vesicular Stomatitis
Solution structure of the C-terminal nucleoprotein-RNA binding domain of the vesicular stomatitis virus phosphoprotein.
Vesicular Stomatitis
Specific interaction of heterogeneous nuclear ribonucleoprotein particle U with the leader RNA sequence of vesicular stomatitis virus.
Vesicular Stomatitis
Spring viremia of carp virus RNA and virion-associated transcriptase activity.
Vesicular Stomatitis
Stabilization of vesicular stomatitis virus L polymerase protein by P protein binding: a small deletion in the C-terminal domain of L abrogates binding.
Vesicular Stomatitis
Stimulation of vesicular stomatitis virus in vitro RNA synthesis by microtubule-associated proteins.
Vesicular Stomatitis
Structure and Function of the N-Terminal Domain of the Vesicular Stomatitis Virus RNA Polymerase.
Vesicular Stomatitis
Structure and function of the RNA polymerase of vesicular stomatitis virus.
Vesicular Stomatitis
Temperature sensitivity of the transcriptase of mutants tsB1 and tsF1 of vesicular stomatitis virus New Jersey is a consequence of mutation affecting polypeptide L.
Vesicular Stomatitis
Temperature-dependent host range mutation in vesicular stomatitis virus affecting polypeptide L.
Vesicular Stomatitis
Temperature-sensitive mutants of vesicular stomatitis virus: comparison of the in vitro RNA polymerase defects of group I and group IV mutants.
Vesicular Stomatitis
Temperature-sensitive mutants of vesicular stomatitis virus: viral RNA synthesis in cells infected with mutants belonging to complementation group I.
Vesicular Stomatitis
The 5' terminal structure of the methylated mRNA synthesized in vitro by vesicular stomatitis virus.
Vesicular Stomatitis
The complete sequence of a unique RNA species synthesized by a DI particle of VSV.
Vesicular Stomatitis
The cost of replication fidelity in an RNA virus.
Vesicular Stomatitis
The Discovery of Reverse Transcriptase.
Vesicular Stomatitis
The L protein of vesicular stomatitis virus transcription complexes is specifically photolabelled by 5-azido-uridine 5'-triphosphate, an analogue of the RNA polymerase substrate uridine 5'-triphosphate.
Vesicular Stomatitis
The Methyltransferase Region of Vesicular Stomatitis Virus L Polymerase Is a Target Site for Functional Intramolecular Insertion.
Vesicular Stomatitis
The role of polypeptides L and NS in the transcription process of vesicular stomatitis virus New Jersey using the temperature-sensitive mutant tsE1.
Vesicular Stomatitis
Transcriptase activity associated with rabies virion.
Vesicular Stomatitis
Transcriptional activity and mutational analysis of recombinant vesicular stomatitis virus RNA polymerase.
Vesicular Stomatitis
Transcriptional control of the RNA-dependent RNA polymerase of vesicular stomatitis virus.
Vesicular Stomatitis
Translation and identification of the mRNA species synthesized in vitro by the virion-associated RNA polymerase of vesicular stomatitis virus.
Vesicular Stomatitis
Two methyltransferase activities in the purified virions of vesicular stomatitis virus.
Vesicular Stomatitis
Two RNA polymerase complexes from vesicular stomatitis virus-infected cells that carry out transcription and replication of genome RNA.
Vesicular Stomatitis
Two separate domains within vesicular stomatitis virus phosphoprotein support transcription when added in trans.
Vesicular Stomatitis
Unconventional mechanism of mRNA capping by the RNA-dependent RNA polymerase of vesicular stomatitis virus.
Vesicular Stomatitis
Unique capping activity of the recombinant RNA polymerase (L) of vesicular stomatitis virus: association of cellular capping enzyme with the L protein.
Vesicular Stomatitis
Use of a hybrid infectivity assay to analyze primary transcription of temperature-sensitive mutants of the New Jersey serotype of vesicular stomatitis virus.
Vesicular Stomatitis
Vesicular stomatitis virion-associated transcriptase activity was suppressed in vitro by a synthetic 21 amino acid oligopeptide prepared to mimic the carboxy-terminus of NS protein.
Vesicular Stomatitis
Vesicular Stomatitis Virus and DNA Vaccines Expressing Zika Virus Nonstructural Protein 1 Induce Substantial but Not Sterilizing Protection against Zika Virus Infection.
Vesicular Stomatitis
Vesicular stomatitis virus mutants resistant to defective-interfering particles accumulate stable 5'-terminal and fewer 3'-terminal mutations in a stepwise manner.
Vesicular Stomatitis
Vesicular stomatitis virus RNA polymerase can read through the boundary between the leader and N genes in vitro.
Vesicular Stomatitis
Vesicular stomatitis virus-based vaccines expressing EV71 virus-like particles elicit strong immune responses and protect newborn mice from lethal challenges.
Vesicular Stomatitis
Vesicular stomatitis virus: mode of transcription.
Vesicular Stomatitis
Visualization of intracellular transport of vesicular stomatitis virus nucleocapsids in living cells.
Vesicular Stomatitis
[RNA polymerase in virions of vesicular stomatitis virus (author's transl)]
Viremia
5'-Terminal Sequences of Spring Viremia of Carp Virus RNA Synthesized In Vitro.
Viremia
Alpha interferon is a powerful adjuvant for a recombinant protein vaccine against foot-and-mouth disease virus in swine, and an effective stimulus of in vivo immune response.
Viremia
An Evidence-Based Algorithm for Early Prognosis of Severe Dengue in the Outpatient Setting.
Viremia
Antibody responses in parvovirus B19 infected patients.
Viremia
Assessment of hepatitis C virus RNA levels by quantitative competitive RNA polymerase chain reaction: high-titer viremia correlates with advanced stage of disease.
Viremia
Determination of viremia and concentration of circulating nonstructural protein 1 in patients infected with dengue virus in Mexico.
Viremia
Do statins reduce hepatitis C RNA titers during routine clinical use?
Viremia
Effects of Short-Course Oral Corticosteroid Therapy in Early Dengue Infection in Vietnamese Patients: A Randomized, Placebo-Controlled Trial.
Viremia
Enhanced detection of antibodies to hepatitis C virus by use of a third-generation recombinant immunoblot assay.
Viremia
In-vitro inhibition of spring viremia of carp virus replication by RNA interference targeting the RNA-dependent RNA polymerase gene.
Viremia
Kinetics of plasma viremia and soluble nonstructural protein 1 concentrations in dengue: differential effects according to serotype and immune status.
Viremia
Nonstructural protein NS1 immunodominant epitope detected specifically in dengue virus infected material by a SELDI-TOF/MS based assay.
Viremia
NS1 Antigenemia and Viraemia Load: Potential Markers of Progression to Dengue Fatal Outcome?
Viremia
Persistent hepatitis C virus infection after liver transplantation: clinical and virological features.
Viremia
Polymorphisms of NS5B protein relates to early clearance of hepatitis C virus by interferon plus ribavirin: a pilot study.
Viremia
Protection against yellow fever in monkeys by immunization with yellow fever virus nonstructural protein NS1.
Viremia
Reliability of the third-generation recombinant immunoblot assay for hepatitis C virus.
Viremia
Remdesivir failure with SARS-CoV-2 RNA-dependent RNA-polymerase mutation in a B-cell immunodeficient patient with protracted Covid-19.
Viremia
Reovirus nonstructural protein sigma1s is required for establishment of viremia and systemic dissemination.
Viremia
Safety and efficacy of lamivudine-zidovudine combination therapy in antiretroviral-naive patients. A randomized controlled comparison with zidovudine monotherapy. Lamivudine European HIV Working Group.
Viremia
Spring viremia of carp virus RNA and virion-associated transcriptase activity.
Viremia
Synthesis of capped and uncapped methylated oligonucleotides by the virion transcriptase of spring viremia of carp virus, a rhabdovirus.
Viremia
Systemic Expression of a Viral RdRP Protects Against Retrovirus Infection and Disease.
Viremia
The effect of freeze-dried Carica papaya leaf juice treatment on NS1 and viremia levels in dengue fever mice model.
Virus Diseases
"Inapparent" hepatitis B virus infection and hepatitis C virus replication in alcoholic subjects with and without liver disease.
Virus Diseases
A glycine-rich RNA-binding protein gene is differentially expressed during acute hypersensitive response following Tobacco Mosaic Virus infection in tobacco.
Virus Diseases
A novel role for RAX, the cellular activator of PKR, in synergistically stimulating SV40 large T antigen-dependent gene expression.
Virus Diseases
A recombinant foot-and-mouth disease virus antigen inhibits DNA replication and triggers the SOS response in Escherichia coli.
Virus Diseases
A tobacco CBL-interacting protein kinase homolog is involved in phosphorylation of the N-terminal domain of the cucumber mosaic virus polymerase 2a protein.
Virus Diseases
Acute enterovirus infection followed by myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and viral persistence.
Virus Diseases
An important role of an inducible RNA-dependent RNA polymerase in plant antiviral defense.
Virus Diseases
Analysis of SARS-CoV-2 RNA-dependent RNA polymerase as a potential therapeutic drug target using a computational approach.
Virus Diseases
Analysis of the involvement of an inducible Arabidopsis RNA-dependent RNA polymerase in antiviral defense.
Virus Diseases
Anti-influenza activity of c60 fullerene derivatives.
Virus Diseases
Antiviral effects of single-stranded polynucleotide inhibitors of the influenza virion-associated transcriptase against influenza virus infection of hamsters and ferrets.
Virus Diseases
Approved Antiviral Drugs over the Past 50 Years.
Virus Diseases
Arabidopsis RNA-dependent RNA polymerases and dicer-like proteins in antiviral defense and small interfering RNA biogenesis during Turnip Mosaic Virus infection.
Virus Diseases
Beclin1 restricts RNA virus infection in plants through suppression and degradation of the viral polymerase.
Virus Diseases
Betanodavirus B2 is an RNA interference antagonist that facilitates intracellular viral RNA accumulation.
Virus Diseases
Bovine viral diarrhea virus nonstructural protein 5A interacts with NIK and IKK{beta}-binding protein (NIBP).
Virus Diseases
Characterization of soluble RNA-dependent RNA polymerase from dengue virus serotype 2: The polyhistidine tag compromises the polymerase activity.
Virus Diseases
Characterization of the stimulators of protein-directed ribosomal frameshifting in Theiler's murine encephalomyelitis virus.
Virus Diseases
Classical Swine Fever Virus p7 Protein Interacts with Host Protein CAMLG and Regulates Calcium Permeability at the Endoplasmic Reticulum.
Virus Diseases
Clinical Pharmacokinetics and Pharmacodynamics of Ledipasvir/Sofosbuvir, a Fixed-Dose Combination Tablet for the Treatment of Hepatitis C.
Virus Diseases
Combination of Nonstructural Protein 1-Based Enzyme-Linked Immunosorbent Assays Can Detect and Distinguish Various Dengue Virus and Zika Virus Infections.
Virus Diseases
Combinations of favipiravir and peramivir for the treatment of pandemic influenza A/California/04/2009 (H1N1) virus infections in mice.
Virus Diseases
Comparative Evaluation of Tears and Nasopharyngeal Swab for SARS-CoV-2 in COVID-19 Dedicated Intensive Care Unit Patients.
Virus Diseases
Comparative studies on ribonucleic acid dependent RNA polymerases in cucumber mosaic virus infected cucumber and tobacco and uninfected tobacco plants.
Virus Diseases
Comparison of capture immunoglobulin M (IgM) and IgG enzyme-linked immunosorbent assay (ELISA) and nonstructural protein NS1 serotype-specific IgG ELISA for differentiation of primary and secondary dengue virus infections.
Virus Diseases
Correction. Arabidopsis RNA-dependent RNA polymerases and dicer-like proteins in antiviral defense and small interfering RNA biogenesis during Turnip mosaic virus infection.
Virus Diseases
Current approaches for target-specific drug discovery using natural compounds against SARS-CoV-2 infection.
Virus Diseases
Cytoplasmic viral RNA-dependent RNA polymerase disrupts the intracellular splicing machinery by entering the nucleus and interfering with Prp8.
Virus Diseases
Dengue virus nonstructural protein 1 is expressed in a glycosyl-phosphatidylinositol-linked form that is capable of signal transduction.
Virus Diseases
Detection of antibodies specific for foot-and-mouth disease virus infection using indirect ELISA based on recombinant nonstructural protein 2B.
Virus Diseases
Detection of dengue virus nonstructural protein 1 (NS1) by using ELISA as a useful laboratory diagnostic method for dengue virus infection of international travelers.
Virus Diseases
Detection of Dengue Virus Nonstructural Protein 1 (NS1) in Urine Samples using ELISA as a Laboratory Diagnostic Method for Dengue Virus Infection.
Virus Diseases
Detection of hepatitis C virus NS5 protein and genome in Chinese carcinoma of the extrahepatic bile duct and its significance.
Virus Diseases
Detection of HIV-1 provirus and RNA by in situ amplification.
Virus Diseases
Determination of Etiology and Epidemiology of Viral Central Nervous System Infections by Quantitative Real-Time Polymerase Chain Reaction in Central India Population.
Virus Diseases
Development of IFN-Stimulated Gene Expression from Embryogenesis through Adulthood, with and without Constitutive MDA5 Pathway Activation.
Virus Diseases
Diagnostic approach for differentiating infected from vaccinated poultry on the basis of antibodies to NS1, the nonstructural protein of influenza A virus.
Virus Diseases
Diagnostic potential of recombinant nonstructural protein 3B to detect antibodies induced by foot-and-mouth disease virus infection in bovines.
Virus Diseases
Differential inductions of RNA silencing among encapsidated double-stranded RNA mycoviruses in the white root rot fungus, Rosellinia necatrix.
Virus Diseases
Distribution and dynamics of transcription-associated proteins during parvovirus infection.
Virus Diseases
Distribution of lignin-carbohydrate complex in plant kingdom and its functionality as alternative medicine.
Virus Diseases
Distribution of naturally -occurring NS5B resistance-associated substitutions in Egyptian patients with chronic Hepatitis C.
Virus Diseases
Domestic dengue infection with hemophagocytic lymphohistiocytosis successfully treated by early steroid therapy.
Virus Diseases
Drug-Drug Interaction Profile of the Fixed-Dose Combination Tablet Regimen Ledipasvir/Sofosbuvir.
Virus Diseases
DWV Infection in vitro Using Honey Bee Pupal Tissue.
Virus Diseases
eEF1G interaction with foot-and-mouth disease virus nonstructural protein 2B: Identification by yeast two-hybrid system.
Virus Diseases
Emetine, a potent alkaloid for the treatment of SARS-CoV-2 targeting papain-like protease and non-structural proteins: pharmacokinetics, molecular docking and dynamic studies.
Virus Diseases
Engineering partial resistance to cucumber mosaic virus in tobacco using intrabodies specific for the viral polymerase.
Virus Diseases
Enhancing the Antiviral Efficacy of RNA-Dependent RNA Polymerase Inhibition by Combination with Modulators of Pyrimidine Metabolism.
Virus Diseases
Entry of sapelovirus into IPEC-J2 cells is dependent on caveolae-mediated endocytosis.
Virus Diseases
Establishment of an immunoscreening system using recombinant VP1 protein for the isolation of a monoclonal antibody that blocks JC virus infection.
Virus Diseases
Ethanolic Extract of Melia Fructus Has Anti-influenza A Virus Activity by Affecting Viral Entry and Viral RNA Polymerase.
Virus Diseases
Expression of the dengue virus type 2 NS5 protein in a CD4(+) T cell line inhibits HIV replication.
Virus Diseases
Flaviviridae virus nonstructural proteins 5 and 5A mediate viral immune evasion and are promising targets in drug development.
Virus Diseases
Flavivirus NS1 Triggers Tissue-Specific Vascular Endothelial Dysfunction Reflecting Disease Tropism.
Virus Diseases
Generation of mutant Uukuniemi viruses lacking the nonstructural protein NSs by reverse genetics indicates that NSs is a weak interferon antagonist.
Virus Diseases
Genome-wide identification of Dicer-like, Argonaute and RNA-dependent RNA polymerase gene families and their expression analyses in response to viral infection and abiotic stresses in Solanum lycopersicum.
Virus Diseases
Hepatitis C Virus NS5A Targets Nucleosome Assembly Protein NAP1L1 To Control the Innate Cellular Response.
Virus Diseases
High circulating levels of the dengue virus nonstructural protein NS1 early in dengue illness correlate with the development of dengue hemorrhagic fever.
Virus Diseases
High levels of serum hyaluronan is an early predictor of dengue warning signs and perturbs vascular integrity.
Virus Diseases
Highlights in the development of new antiviral agents.
Virus Diseases
Human microRNA hsa-miR-15b-5p targets the RNA template component of the RNA-dependent RNA polymerase structure in severe acute respiratory syndrome coronavirus 2.
Virus Diseases
Identification and characterization of a baboon reovirus-specific nonstructural protein encoded by the bicistronic s4 genome segment.
Virus Diseases
Identification, sequence, and expression of the gene encoding a Mr 35,000 subunit of the vaccinia virus DNA-dependent RNA polymerase.
Virus Diseases
Immune response to a hepatitis C virus nonstructural protein in chronic hepatitis C virus infection.
Virus Diseases
Immunoassay targeting nonstructural protein 5 to differentiate West Nile virus infection from dengue and St. Louis encephalitis virus infections and from flavivirus vaccination.
Virus Diseases
Immunogenic characterization and epitope mapping of transmissible gastroenteritis virus RNA dependent RNA polymerase.
Virus Diseases
Improved immunogenicity of a peptide epitope after fusion to hepatitis B core protein.
Virus Diseases
Improving dengue viral antigens detection in dengue patient serum specimens using a low pH glycine buffer treatment.
Virus Diseases
Indirect ELISA using recombinant nonstructural protein 3D to detect foot and mouth disease virus infection associated antibodies.
Virus Diseases
Inducible CYP4F12 enhances Hepatitis C virus infection via association with viral nonstructural protein 5B.
Virus Diseases
Infection-Induced Retrotransposon-Derived Noncoding RNAs Enhance Herpesviral Gene Expression via the NF-?B Pathway.
Virus Diseases
Influenza A virus NS1 protein activates the PI3K/Akt pathway to mediate antiapoptotic signaling responses.
Virus Diseases
Influenza Virus Infection Induces Host Pyruvate Kinase M Which Interacts with Viral RNA-Dependent RNA Polymerase.
Virus Diseases
Inhibition of RNA binding to hepatitis C virus RNA-dependent RNA polymerase: a new mechanism for antiviral intervention.
Virus Diseases
Insights into RNA-dependent RNA Polymerase Inhibitors as Anti-influenza Virus Agents.
Virus Diseases
Interaction between hantavirus nucleocapsid protein (N) and RNA-dependent RNA polymerase (RdRp) mutants reveals the requirement of an N-RdRp interaction for viral RNA synthesis.
Virus Diseases
Interactome Analysis of NS1 Protein Encoded by Influenza A H7N9 Virus Reveals an Inhibitory Role of NS1 in Host mRNA Maturation.
Virus Diseases
Interference with viral infection by defective RNA replicase.
Virus Diseases
Interference with viral infection by RNA replicase deleted at the carboxy-terminal region.
Virus Diseases
Lignified materials as potential medicinal resources. III. Diversity of biological activity and possible molecular species involved.
Virus Diseases
Marine Oomycetes of the Genus Halophytophthora Harbor Viruses Related to Bunyaviruses.
Virus Diseases
Mechanistic Aspects of Medicinal Plants and Secondary Metabolites against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).
Virus Diseases
Microbes and microbial toxins: paradigms for microbial-mucosal interactions. VIII. Pathological consequences of rotavirus infection and its enterotoxin.
Virus Diseases
MicroRNA-146a promotes red spotted grouper nervous necrosis virus (RGNNV) replication by targeting TRAF6 in orange spotted grouper, Epinephelus coioides.
Virus Diseases
Mink Enteritis Virus Infection Induces Mitochondrion-mediated Apoptosis by the Viral Nonstructural Protein 1.
Virus Diseases
miRNA-200c-3p is crucial in acute respiratory distress syndrome.
Virus Diseases
Modification of RNA polymerase IIO subspecies after poliovirus infection.
Virus Diseases
Monoclonal antibodies against foot-and-mouth disease virus RNA polymerase for detection of virus infection.
Virus Diseases
Mutational analysis of Rift Valley fever phlebovirus nucleocapsid protein indicates novel conserved, functional amino acids.
Virus Diseases
Natural history of GBV-C/hepatitis G virus infection through the follow-up of GBV-C/hepatitis G virus-infected blood donors and recipients studied by RNA polymerase chain reaction and anti-E2 serology.
Virus Diseases
Nonstructural protein 1 antibody-based epitope-blocking enzyme-linked immunosorbent assay to differentiate Japanese encephalitis virus from dengue virus infections in humans.
Virus Diseases
Nonstructural protein NS4 of Rice Stripe Virus plays a critical role in viral spread in the body of vector insects.
Virus Diseases
Nonstructural Protein NSs Hampers Cellular Antiviral Response through LSm14A during Severe Fever with Thrombocytopenia Syndrome Virus Infection.
Virus Diseases
Nonstructural protein of infectious bursal disease virus inhibits apoptosis at the early stage of virus infection.
Virus Diseases
Nonstructural protein Pns12 of rice dwarf virus is a principal regulator for viral replication and infection in its insect vector.
Virus Diseases
Nonstructural protein Pns4 of rice dwarf virus is essential for viral infection in its insect vector.
Virus Diseases
Novel guanosine derivatives against Zika virus polymerase in silico.
Virus Diseases
NP and NS1 proteins of H5N1 virus significantly upregulated IFITM1, IFITM2, and IFITM3 in A549 cells.
Virus Diseases
NS5B RNA Dependent RNA Polymerase Inhibitors: The Promising Approach to Treat Hepatitis C Virus Infections.
Virus Diseases
Nuclear localization of dengue virus nonstructural protein 5 through its importin alpha/beta-recognized nuclear localization sequences is integral to viral infection.
Virus Diseases
Nucleolin Promotes IRES-Driven Translation of Foot-and-Mouth Disease Virus by Supporting the Assembly of Translation Initiation Complexes.
Virus Diseases
Optimizing choice of oral interferon-free treatment for genotype 1 hepatitis C virus using testing for NS5A resistance: a cost-utility analysis from the perspective of the Italian National Health Service.
Virus Diseases
Persistent noncytocidal vesicular stomatitis virus infections mediated by defective T particles that suppress virion transcriptase.
Virus Diseases
Phenotypic characterization of mutants in vaccinia virus gene G2R, a putative transcription elongation factor.
Virus Diseases
Phosphorylation of cucumber mosaic virus RNA polymerase 2a protein inhibits formation of replicase complex.
Virus Diseases
Phosphorylation of the viral nonstructural protein NS1 during MVMp infection of A9 cells.
Virus Diseases
Phosphorylation of viral RNA-dependent RNA polymerase and its role in replication of a plus-strand RNA virus.
Virus Diseases
Posttranscriptional Control of Type I Interferon Genes by KSRP in the Innate Immune Response against Viral Infection.
Virus Diseases
Potent host-directed small-molecule inhibitors of myxovirus RNA-dependent RNA-polymerases.
Virus Diseases
Potential application of nonstructural protein NS1 serotype-specific immunoglobulin G enzyme-linked immunosorbent assay in the seroepidemiologic study of dengue virus infection: correlation of results with those of the plaque reduction neutralization test.
Virus Diseases
Potential Phosphorylation of Viral Nonstructural Protein 1 in Dengue Virus Infection.
Virus Diseases
Protection against Dengue Virus Infection in Mice by Administration of Antibodies against Modified Nonstructural Protein 1.
Virus Diseases
Proteomic analyses identify intracellular targets for Japanese encephalitis virus nonstructural protein 1 (NS1).
Virus Diseases
Re-evaluation of the pathogenic roles of nonstructural protein 1 and its antibodies during dengue virus infection.
Virus Diseases
Recent advances in the development of NS5B polymerase inhibitors for the treatment of hepatitis C virus infection.
Virus Diseases
Recent advances in the discovery of potent RNA-dependent RNA-polymerase (RdRp) inhibitors targeting viruses.
Virus Diseases
Recombinant virus like particles as drug delivery system.
Virus Diseases
Recombinant VP1 protein as a potential marker for the diagnosis of acute hepatitis A virus infection.
Virus Diseases
Remdesivir and SARS-CoV-2: Structural requirements at both nsp12 RdRp and nsp14 Exonuclease active-sites.
Virus Diseases
Resistance to Plum pox virus in plants expressing cytosolic and nuclear single?chain antibodies against the viral RNA NIb replicase
Virus Diseases
Reversal of nonstructural protein 3-specific CD4(+) T cell dysfunction in patients with persistent hepatitis C virus infection.
Virus Diseases
Review article: the efficacy and safety of sofosbuvir, a novel, oral nucleotide NS5B polymerase inhibitor, in the treatment of chronic hepatitis C virus infection.
Virus Diseases
RNA dependent RNA polymerase activity associated with the double-stranded RNA virus of Giardia lamblia.
Virus Diseases
RNA-Dependent RNA Polymerase 1 from Nicotiana tabacum Suppresses RNA Silencing and Enhances Viral Infection in Nicotiana benthamiana.
Virus Diseases
RNA-dependent RNA polymerase of tobacco plants.
Virus Diseases
Role of C14orf166 in viral infection and RNA metabolism and its relationship with cancer (Review).
Virus Diseases
Role of cellular RNA polymerases in virus-induced leukemogenesis.
Virus Diseases
Roles of nonstructural protein nsP2 and Alpha/Beta interferons in determining the outcome of Sindbis virus infection.
Virus Diseases
Salicylic acid treatment and expression of an RNA-dependent RNA polymerase 1 transgene inhibit lethal symptoms and meristem invasion during tobacco mosaic virus infection in Nicotiana benthamiana.
Virus Diseases
SAR study of bisamides as cyclophilin a inhibitors for the development of host-targeting therapy for hepatitis C virus infection.
Virus Diseases
SCE1, the SUMO-Conjugating Enzyme in Plants That Interacts with NIb, the RNA-Dependent RNA Polymerase of Turnip Mosaic Virus, Is Required for Viral Infection.
Virus Diseases
Serologic Prevalence of MPV1 in Mouse Strains in a Commercial Laboratory Mouse Colony Determined by Using VP1 Antigen.
Virus Diseases
Serotype 1-specific monoclonal antibody-based antigen capture immunoassay for detection of circulating nonstructural protein NS1: Implications for early diagnosis and serotyping of dengue virus infections.
Virus Diseases
Sofosbuvir as a potential alternative to treat the SARS-CoV-2 epidemic.
Virus Diseases
Structural Decoding of a Small Molecular Inhibitor on the Binding of SARS-CoV-2 to the ACE 2 Receptor.
Virus Diseases
Structure of nonstructural protein 1 from SARS-CoV-2.
Virus Diseases
Structure of Nonstructural Protein 1 from SARS-CoV-2.
Virus Diseases
Studies of the Interaction of Influenza Virus RNA Polymerase PAN with Endonuclease Inhibitors.
Virus Diseases
Sumoylation of Turnip mosaic virus RNA polymerase promotes viral infection by counteracting the host NPR1-mediated immune response.
Virus Diseases
Sumoylation-promoted enterovirus 71 3C degradation correlates with a reduction in viral replication and cell apoptosis.
Virus Diseases
Temperature Sensitive Mutations in Influenza A Viral Ribonucleoprotein Complex Responsible for the Attenuation of the Live Attenuated Influenza Vaccine.
Virus Diseases
The effects of autophagy on the replication of Nelson Bay orthoreovirus.
Virus Diseases
The Potyvirus Silencing Suppressor Protein VPg Mediates Degradation of SGS3 via Ubiquitination and Autophagy Pathways.
Virus Diseases
The prevalence of enteroviral RNA and protein in mitral valves of chronic rheumatic heart disease.
Virus Diseases
The RNA-Dependent RNA Polymerase NIb of Potyviruses Plays Multifunctional, Contrasting Roles during Viral Infection.
Virus Diseases
The RNA-dependent RNA polymerase of cowpea is not involved in cowpea mosaic virus RNA replication: immunological evidence.
Virus Diseases
The role of the influenza virus RNA polymerase in host shut-off.
Virus Diseases
The ubiquitin-proteasome system regulates the accumulation of Turnip yellow mosaic virus RNA-dependent RNA polymerase during viral infection.
Virus Diseases
The Whys and Wherefores of Transitivity in Plants.
Virus Diseases
Theiler's virus infection induces a predominant pathogenic CD4+ T cell response to RNA polymerase in susceptible SJL/J mice.
Virus Diseases
Tobacco RNA-dependent RNA polymerase 1 affects the expression of defence-related genes in Nicotiana benthamiana upon Tomato leaf curl Gujarat virus infection.
Virus Diseases
Topical Application of Escherichia coli-Encapsulated dsRNA Induces Resistance in Nicotiana benthamiana to Potato Viruses and Involves RDR6 and Combined Activities of DCL2 and DCL4.
Virus Diseases
Transgenic Expression of the 3D Polymerase Inhibits Theiler's Virus Infection and Demyelination.
Virus Diseases
Use of Urea Wash ELISA to Distinguish Zika and Dengue Virus Infections.
Virus Diseases
Viral RNA-dependent RNA polymerase inhibitor 7-deaza-2'-C-methyladenosine prevents death in a mouse model of West Nile virus infection.
Virus Diseases
Viral RNA-dependent RNA polymerase mutants display an altered mutation spectrum resulting in attenuation in both mosquito and vertebrate hosts.
Virus Diseases
Viral Transcription During Autographa californica Nuclear Polyhedrosis Virus Infection: a Novel RNA Polymerase Induced in Infected Spodoptera frugiperda Cells.
Virus Diseases
Viroinformatics-Based Analysis of SARS-CoV-2 Core Proteins for Potential Therapeutic Targets.
Virus Diseases
VX-222, a non-nucleoside NS5B polymerase inhibitor, in telaprevir-based regimens for genotype 1 hepatitis C virus infection.
Virus Diseases
Worldwide distribution of the NS3 gene 80K polymorphism among circulating hepatitis C genotype 1 viruses: implication for simeprevir usage.
Virus Diseases
[Competitive evolution of enzymatic activities of the transcriptase and replicase type during a viral disease in cattle]
Virus Diseases
[Marburg and Ebola hemorrhagic fevers--pathogens, epidemiology and therapy].
Vision Disorders
Congenital Visual Impairment and Progressive Microcephaly Due to Lysyl-Transfer Ribonucleic Acid (RNA) Synthetase (KARS) Mutations: The Expanding Phenotype of Aminoacyl-Transfer RNA Synthetase Mutations in Human Disease.
Vitamin B 6 Deficiency
Vitamin B6 deficiency causes activation of RNA polymerase and general enhancement of gene expression in rat liver.
Warts
Approved Antiviral Drugs over the Past 50 Years.
Werner Syndrome
Roles of RNase P and Its Subunits.
West Nile Fever
Immunoassay targeting nonstructural protein 5 to differentiate West Nile virus infection from dengue and St. Louis encephalitis virus infections and from flavivirus vaccination.
West Nile Fever
New avenues for therapeutic discovery against West Nile virus.
West Nile Fever
Persistence of antibodies to West Nile virus nonstructural protein 5.
West Nile Fever
Viral RNA-dependent RNA polymerase inhibitor 7-deaza-2'-C-methyladenosine prevents death in a mouse model of West Nile virus infection.
Whooping Cough
A Mutation Upstream of the rplN-rpsD Ribosomal Operon Downregulates Bordetella pertussis Virulence Factor Production without Compromising Bacterial Survival within Human Macrophages.
Whooping Cough
A new gene locus of Bordetella pertussis defines a novel family of prokaryotic transcriptional accessory proteins.
Whooping Cough
Bordetella pertussis fim3 gene regulation by BvgA: Phosphorylation controls the formation of inactive vs. active transcription complexes.
Whooping Cough
Differential binding of BvgA to two classes of virulence genes of Bordetella pertussis directs promoter selectivity by RNA polymerase.
Whooping Cough
Effect of mutations causing overexpression of RNA polymerase alpha subunit on regulation of virulence factors in Bordetella pertussis.
Whooping Cough
Mutations affecting the alpha subunit of Bordetella pertussis RNA polymerase suppress growth inhibition conferred by short C-terminal deletions of the response regulator BvgA.
Whooping Cough
Nature of DNA binding and RNA polymerase interaction of the Bordetella pertussis BvgA transcriptional activator at the fha promoter.
Whooping Cough
Overexpression of the RNA polymerase alpha subunit reduces transcription of Bvg-activated virulence genes in Bordetella pertussis.
Whooping Cough
Synergistic binding of RNA polymerase and BvgA phosphate to the pertussis toxin promoter of Bordetella pertussis.
Whooping Cough
The Bordetella pertussis model of exquisite gene control by the global transcription factor BvgA.
Whooping Cough
The Bordetella pertussis sigma subunit of RNA polymerase confers enhanced expression of fha in Escherichia coli.
Wilms Tumor
Genomic characterization of Wilms' tumor suppressor 1 targets in nephron progenitor cells during kidney development.
Wiskott-Aldrich Syndrome
A novel role of the actin-nucleating Arp2/3 complex in the regulation of RNA polymerase II-dependent transcription.
Wiskott-Aldrich Syndrome
Mutations of RNA polymerase II activate key genes of the nucleoside triphosphate biosynthetic pathways.
Wolf-Hirschhorn Syndrome
Evidence that negative elongation factor represses transcription elongation through binding to a DRB sensitivity-inducing factor/RNA polymerase II complex and RNA.
Wound Infection
Evaluation of Bacterial RNA Polymerase Inhibitors in a Staphylococcus aureus-Based Wound Infection Model in SKH1 Mice.
Xeroderma Pigmentosum
Adenovirus type 12-induced fragility of the human RNU2 locus requires p53 function.
Yellow Fever
Beyond Members of the Flaviviridae Family, Sofosbuvir Also Inhibits Chikungunya Virus Replication.
Yellow Fever
Fluorescent tagging the NS1 protein in yellow fever virus: Replication-capable viruses which produce the secretory GFP-NS1 fusion protein.
Yellow Fever
Genetic interaction of flavivirus nonstructural proteins NS1 and NS4A as a determinant of replicase function.
Yellow Fever
Glycosylation and secretion of yellow fever virus nonstructural protein NS1.
Yellow Fever
High fidelity of yellow fever virus RNA polymerase.
Yellow Fever
Identification of three H-2K(d) restricted CTL epitopes of NS4A and NS4B protein from Yellow fever 17D vaccine.
Yellow Fever
Mutation in NS5 protein attenuates mouse neurovirulence of yellow fever 17D vaccine virus.
Yellow Fever
Mutation of critical residues reveals insights of yellow fever virus nonstructural protein 1 (NS1) stability and its formation.
Yellow Fever
Mutations in the yellow fever virus nonstructural protein NS2A selectively block production of infectious particles.
Yellow Fever
Protection against yellow fever in monkeys by immunization with yellow fever virus nonstructural protein NS1.
Yellow Fever
Repositioning of RdRp Inhibitors against HCV NS5B Polymerase Utilizing Structure-Based Molecular Docking.
Yellow Fever
Repurposing Old Antibodies for New Diseases by Exploiting Cross-Reactivity and Multicolored Nanoparticles.
Yellow Fever
Structural and Nonstructural Genes Contribute to the Genetic Diversity of RNA Viruses.
Yellow Fever
Structure of the yellow fever NS5 protein reveals conserved drug targets shared among flaviviruses.
Yellow Fever
The eukaryotic translation initiation factor 3 subunit L protein interacts with Flavivirus NS5 and may modulate yellow fever virus replication.
Yellow Fever
The interferon signaling antagonist function of yellow fever virus NS5 protein is activated by type I interferon.
Yellow Fever
The nucleotide sequence of dengue type 4 virus: analysis of genes coding for nonstructural proteins.
Yellow Fever
The Role of NS5 Protein in Determination of Host Cell Range for Yellow Fever Virus.
Yellow Fever
The small nuclear ribonucleoprotein U1A interacts with NS5 from yellow fever virus.
Yellow Fever
trans-Complementation of yellow fever virus NS1 reveals a role in early RNA replication.
Yellow Fever
Vesicular Stomatitis Virus and DNA Vaccines Expressing Zika Virus Nonstructural Protein 1 Induce Substantial but Not Sterilizing Protection against Zika Virus Infection.
Yellow Fever
Yellow Fever virus NS3 plays an essential role in virus assembly independent of its known enzymatic functions.
Yersinia Infections
Identification of beta-subunit of bacterial RNA-polymerase--a non-species-specific bacterial protein--as target of antibodies in primary biliary cirrhosis.
Zika Virus Infection
Cranial US in Infants Exposed to Zika Virus: The NATZIG Cohort.
Zika Virus Infection
Delayed and highly specific antibody response to nonstructural protein 1 (NS1) revealed during natural human ZIKV infection by NS1-based capture ELISA.
Zika Virus Infection
Diagnosis of Zika virus infection on a nanotechnology platform.
Zika Virus Infection
Doubled dosage of sofosbuvir is expected for inhibiting Zika virus infection.
Zika Virus Infection
Novel guanosine derivatives against Zika virus polymerase in silico.
Zika Virus Infection
Nuclear import inhibitor N-(4-hydroxyphenyl) retinamide targets Zika virus (ZIKV) nonstructural protein 5 to inhibit ZIKV infection.
Zika Virus Infection
Ribavirin inhibits Zika virus (ZIKV) replication in vitro and suppresses viremia in ZIKV-infected STAT1-deficient mice.
Zika Virus Infection
Sophoraflavenone G Restricts Dengue and Zika Virus Infection via RNA Polymerase Interference.
Zika Virus Infection
The NLRP3 inflammasome activation mediates Zika virus associated inflammation.
Zika Virus Infection
The Potential Role of the ZIKV NS5 Nuclear Spherical-Shell Structures in Cell Type-Specific Host Immune Modulation during ZIKV Infection.
Zika Virus Infection
The Screening of phytochemicals against NS5 Polymerase to treat Zika Virus infection: Integrated computational based approach.
Zika Virus Infection
Use of Urea Wash ELISA to Distinguish Zika and Dengue Virus Infections.
Zika Virus Infection
Vesicular Stomatitis Virus and DNA Vaccines Expressing Zika Virus Nonstructural Protein 1 Induce Substantial but Not Sterilizing Protection against Zika Virus Infection.
Zika Virus Infection
Zika Virus NS5 Forms Supramolecular Nuclear Bodies That Sequester Importin-? and Modulate the Host Immune and Pro-Inflammatory Response in Neuronal Cells.
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