Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

BRENDA Home
show all | hide all No of entries

Information on EC 2.7.6.3 - 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase and Organism(s) Pseudomonas aeruginosa

for references in articles please use BRENDA:EC2.7.6.3
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
IUBMB Comments
Binds 2 Mg2+ ions that are essential for activity . The enzyme participates in the biosynthetic pathways for folate (in bacteria, plants, fungi, and some archaeal species, including the haloarchaea) and methanopterin (in some archaeal species such as the Archaeoglobi and Methanobacteria). The enzyme exists in varying types of multifunctional proteins in different organisms. The enzyme from the bacterium Streptococcus pneumoniae also harbours the activity of EC 4.1.2.25, dihydroneopterin aldolase , the enzyme from the plant Arabidopsis thaliana harbours the activity of EC 2.5.1.15, dihydropteroate synthase , while the enzyme from yeast Saccharomyces cerevisiae is trifunctional with both of the two above mentioned activities .
Specify your search results
Select one or more organisms in this record: ?
This record set is specific for:
Pseudomonas aeruginosa
Show additional data
Do not include text mining results
Include (text mining) results
Include results (AMENDA + additional results, but less precise)
Word Map
The taxonomic range for the selected organisms is: Pseudomonas aeruginosa
The enzyme appears in selected viruses and cellular organisms
Synonyms
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase (hppk), 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, cythppk/dhps, fthppk-dhps, 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, hydroxymethyldihydropterin pyrophosphokinase (hppk), hppk/dhps, hydroxymethyldihydropteridine pyrophosphokinase, 6-hydroxymethylpterin pyrophosphokinase, dihydropterin pyrophosphokinase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
-
-
-
-
6-hydroxy-7,8-dihydropterin pyrophosphokinase
-
-
-
-
7,8-dihydro-6-hydroxymethylpterin pyrophosphokinase
-
-
-
-
7,8-dihydroxymethylpterin-pyrophosphokinase
-
-
-
-
ATP:2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine 6'-pyrophosphotransferase
-
-
-
-
H2-pteridine-CH2-OH pyrophosphokinase
-
-
-
-
H2-pteridine-CH2OH pyrophosphokinase
-
-
-
-
HPPK
-
-
-
-
hydroxymethyldihydropteridine pyrophosphokinase
-
-
-
-
pyrophosphokinase, 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine
-
-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
diphosphate transfer
-
-
-
-
PATHWAY SOURCE
PATHWAYS
-
-, -, -, -, -, -
SYSTEMATIC NAME
IUBMB Comments
ATP:6-hydroxymethyl-7,8-dihydropterin 6'-diphosphotransferase
Binds 2 Mg2+ ions that are essential for activity [4]. The enzyme participates in the biosynthetic pathways for folate (in bacteria, plants, fungi, and some archaeal species, including the haloarchaea) and methanopterin (in some archaeal species such as the Archaeoglobi and Methanobacteria). The enzyme exists in varying types of multifunctional proteins in different organisms. The enzyme from the bacterium Streptococcus pneumoniae also harbours the activity of EC 4.1.2.25, dihydroneopterin aldolase [4], the enzyme from the plant Arabidopsis thaliana harbours the activity of EC 2.5.1.15, dihydropteroate synthase [7], while the enzyme from yeast Saccharomyces cerevisiae is trifunctional with both of the two above mentioned activities [6].
CAS REGISTRY NUMBER
COMMENTARY hide
37278-23-2
-
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
A0A8G8JZK1_PSEAI
180
0
20055
TrEMBL
-
A0A8G7H6B7_PSEAI
180
0
20120
TrEMBL
-
A0A3P3MFD4_PSEAI
180
0
20105
TrEMBL
-
A0A0A8RIA2_PSEAI
162
0
18028
TrEMBL
-
A0A643J0T8_PSEAI
162
0
17945
TrEMBL
-
A0A659BMZ9_PSEAI
162
0
18013
TrEMBL
-
A0A8G1K743_PSEAI
180
0
20119
TrEMBL
-
A0A8G6CVG2_PSEAI
162
0
17999
TrEMBL
-
A0A6A9K3M5_PSEAI
180
0
20121
TrEMBL
-
A0A8G4WKG0_PSEAI
162
0
17956
TrEMBL
-
A0A8G3Y0Q5_PSEAI
162
0
18113
TrEMBL
-
A0A8F8RHD3_PSEAI
162
0
17986
TrEMBL
-
A0A8G1Q6V5_PSEAI
162
0
18000
TrEMBL
-
A0A509JGV4_PSEAI
162
0
17939
TrEMBL
-
A0A485FTQ8_PSEAI
180
0
20189
TrEMBL
-
A0A8G6XIM6_PSEAI
180
0
20087
TrEMBL
-
A0A8G7B527_PSEAI
180
0
20050
TrEMBL
-
A0A8B4ZVI0_PSEAI
180
0
20108
TrEMBL
-
A0A8G3T0I8_PSEAI
180
0
20052
TrEMBL
-
A0A072ZDF3_PSEAI
180
0
20135
TrEMBL
-
A0A2R3IPI1_PSEAI
180
0
20152
TrEMBL
-
A0A8G7CTG4_PSEAI
180
0
20135
TrEMBL
-
A0A8G2RIK9_PSEAI
180
0
20168
TrEMBL
-
A0A2R3IRA8_PSEAI
162
0
17838
TrEMBL
-
A0A8F9NQY2_PSEAI
180
0
20102
TrEMBL
-
A0A8G6NRH4_PSEAI
162
0
18042
TrEMBL
-
A0A367GU82_PSEAI
162
0
17987
TrEMBL
-
A0A8G3ASC8_PSEAI
180
0
20071
TrEMBL
-
A0A8B4ZCN3_PSEAI
180
0
20154
TrEMBL
-
A0A6A9JYL1_PSEAI
162
0
17961
TrEMBL
-
A0A431XHD6_PSEAI
180
0
20161
TrEMBL
-
A0A231JXK0_PSEAI
180
0
20140
TrEMBL
-
A0A8G2S0P9_PSEAI
180
0
20122
TrEMBL
-
A0A069QAV9_PSEAI
162
0
18014
TrEMBL
-
A0A8G5ZLH0_PSEAI
180
0
20072
TrEMBL
-
A0A8G2QYQ4_PSEAI
180
0
20125
TrEMBL
-
A0A8G5IWJ7_PSEAI
180
0
20121
TrEMBL
-
A0A485GWD8_PSEAI
162
0
17852
TrEMBL
-
A0A7M3B1P5_PSEAI
180
0
20072
TrEMBL
-
A0A8G2S134_PSEAI
162
0
18042
TrEMBL
-
A0A077JI08_PSEAI
180
0
20091
TrEMBL
-
A0A7M3B4L5_PSEAI
162
0
18072
TrEMBL
-
A0A8G4HND3_PSEAI
180
0
20082
TrEMBL
-
A0A8F9P451_PSEAI
180
0
20119
TrEMBL
-