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Information on EC 2.7.11.18 - myosin-light-chain kinase and Organism(s) Drosophila melanogaster

for references in articles please use BRENDA:EC2.7.11.18
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EC Tree
IUBMB Comments
Requires Ca2+ and calmodulin for activity. The 20-kDa light chain from smooth muscle myosin is phosphorylated more rapidly than any other acceptor, but light chains from other myosins and myosin itself can act as acceptors, but more slowly.
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This record set is specific for:
Drosophila melanogaster
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Word Map
The taxonomic range for the selected organisms is: Drosophila melanogaster
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Synonyms
mlck, myosin light chain kinase, myosin light-chain kinase, mlc kinase, smooth muscle myosin light chain kinase, smmlck, nmmlck, myosin kinase, cmlck, skmlck, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
calcium/calmodulin-dependent myosin light chain kinase
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kinase, myosin light-chain (phosphorylating)
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myosin kinase
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myosin light chain protein kinase
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myosin light-chain kinase
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smooth-muscle-myosin-light-chain kinase
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stretchin-MLCK
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
phospho group transfer
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SYSTEMATIC NAME
IUBMB Comments
ATP:[myosin light chain] O-phosphotransferase
Requires Ca2+ and calmodulin for activity. The 20-kDa light chain from smooth muscle myosin is phosphorylated more rapidly than any other acceptor, but light chains from other myosins and myosin itself can act as acceptors, but more slowly.
CAS REGISTRY NUMBER
COMMENTARY hide
51845-53-5
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
A0A0B4KG35_DROME
8255
0
923798
TrEMBL
other Location (Reliability: 2)
A0A0B4KF84_DROME
8216
0
919345
TrEMBL
other Location (Reliability: 4)
A1ZA73_DROME
1918
0
215065
TrEMBL
other Location (Reliability: 1)
A0A0B4JCU1_DROME
602
0
67243
TrEMBL
other Location (Reliability: 5)
A0A0B4JD64_DROME
913
0
100097
TrEMBL
other Location (Reliability: 5)
Q8MYR8_DROME
576
0
64369
TrEMBL
other Location (Reliability: 5)
A1ZA72_DROME
7944
0
890943
TrEMBL
other Location (Reliability: 2)
Q95SK9_DROME
446
0
50282
TrEMBL
other Location (Reliability: 1)
A1ZA70_DROME
732
0
80500
TrEMBL
other Location (Reliability: 2)
A1Z7Y7_DROME
888
0
97572
TrEMBL
other Location (Reliability: 1)
A0A0B4JD82_DROME
7905
0
886491
TrEMBL
other Location (Reliability: 4)
A1ZA69_DROME
929
0
101986
TrEMBL
other Location (Reliability: 4)
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
926000
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deduced from nucleotide sequence, stretchin-MLCK
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Champagne, M.B.; Edwards, K.A.; Erickson, H.P.; Kiehart, D.P.
Drosophila stretchin-MLCK is a novel member of the titin/myosin light chain kinase family
J. Mol. Biol.
300
759-777
2000
Drosophila melanogaster
Manually annotated by BRENDA team