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Information on EC 2.7.11.13 - protein kinase C and Organism(s) Gallus gallus

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EC Tree
IUBMB Comments
A family of serine- and threonine-specific protein kinases that depend on lipids for activity. They can be activated by calcium but have a requirement for the second messenger diacylglycerol. Members of this group of enzymes phosphorylate a wide variety of protein targets and are known to be involved in diverse cell-signalling pathways. Members of the protein kinase C family also serve as major receptors for phorbol esters, a class of tumour promoters.
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Gallus gallus
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Word Map
The taxonomic range for the selected organisms is: Gallus gallus
The enzyme appears in selected viruses and cellular organisms
Reaction Schemes
+
a [protein]-(L-serine/L-threonine)
=
+
a [protein]-(L-serine/L-threonine) phosphate
Synonyms
protein kinase c, pkcalpha, pkc-alpha, pkc alpha, pkcepsilon, pkc-delta, pkczeta, pkc-epsilon, pkc delta, pkc-zeta, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Calcium-dependent protein kinase C
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epsilonPKC
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PKC
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protein kinase C
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protein kinase-C
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SYSTEMATIC NAME
IUBMB Comments
ATP:protein phosphotransferase (diacylglycerol-dependent)
A family of serine- and threonine-specific protein kinases that depend on lipids for activity. They can be activated by calcium but have a requirement for the second messenger diacylglycerol. Members of this group of enzymes phosphorylate a wide variety of protein targets and are known to be involved in diverse cell-signalling pathways. Members of the protein kinase C family also serve as major receptors for phorbol esters, a class of tumour promoters.
CAS REGISTRY NUMBER
COMMENTARY hide
141436-78-4
calcium-dependent protein kinase C
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
A0A3Q3B2F1_CHICK
954
0
107560
TrEMBL
other Location (Reliability: 2)
E1BQN6_CHICK
592
0
68249
TrEMBL
other Location (Reliability: 4)
F1NHL1_CHICK
899
0
100856
TrEMBL
other Location (Reliability: 5)
Q5F3X1_CHICK
674
0
76846
TrEMBL
other Location (Reliability: 3)
A0A1D5PXN4_CHICK
685
0
78480
TrEMBL
other Location (Reliability: 2)
E1BWA3_CHICK
599
0
68108
TrEMBL
other Location (Reliability: 2)
Q5ZKE2_CHICK
699
0
80197
TrEMBL
other Location (Reliability: 2)
Q5F3M9_CHICK
819
0
91458
TrEMBL
other Location (Reliability: 5)
E1C6T4_CHICK
890
0
100389
TrEMBL
other Location (Reliability: 4)
A0A1D5PUY5_CHICK
672
0
76703
TrEMBL
other Location (Reliability: 2)
E1BYS6_CHICK
1042
0
117310
TrEMBL
Mitochondrion (Reliability: 4)
R4GHL2_CHICK
682
0
77745
TrEMBL
other Location (Reliability: 3)
F1P3G1_CHICK
699
0
80178
TrEMBL
other Location (Reliability: 2)
A0A1D5PCZ1_CHICK
670
0
76478
TrEMBL
other Location (Reliability: 2)
F1NF33_CHICK
947
0
106476
TrEMBL
other Location (Reliability: 2)
F1P0L9_CHICK
464
0
52834
TrEMBL
other Location (Reliability: 2)
F1NJH1_CHICK
682
0
77565
TrEMBL
Mitochondrion (Reliability: 4)
F1NG47_CHICK
743
0
84644
TrEMBL
other Location (Reliability: 3)
Q5F3H2_CHICK
464
0
52800
TrEMBL
other Location (Reliability: 2)