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Information on EC 2.7.11.13 - protein kinase C and Organism(s) Danio rerio

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EC Tree
IUBMB Comments
A family of serine- and threonine-specific protein kinases that depend on lipids for activity. They can be activated by calcium but have a requirement for the second messenger diacylglycerol. Members of this group of enzymes phosphorylate a wide variety of protein targets and are known to be involved in diverse cell-signalling pathways. Members of the protein kinase C family also serve as major receptors for phorbol esters, a class of tumour promoters.
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Danio rerio
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Word Map
The taxonomic range for the selected organisms is: Danio rerio
The enzyme appears in selected viruses and cellular organisms
Reaction Schemes
+
a [protein]-(L-serine/L-threonine)
=
+
a [protein]-(L-serine/L-threonine) phosphate
Synonyms
protein kinase c, pkcalpha, pkc-alpha, pkc alpha, pkcepsilon, pkc-delta, pkczeta, pkc-epsilon, pkc delta, pkc-zeta, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Calcium-dependent protein kinase C
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-
-
-
epsilonPKC
-
-
-
-
PKC
-
-
-
-
protein kinase C
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-
-
-
protein kinase-C
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-
-
-
SYSTEMATIC NAME
IUBMB Comments
ATP:protein phosphotransferase (diacylglycerol-dependent)
A family of serine- and threonine-specific protein kinases that depend on lipids for activity. They can be activated by calcium but have a requirement for the second messenger diacylglycerol. Members of this group of enzymes phosphorylate a wide variety of protein targets and are known to be involved in diverse cell-signalling pathways. Members of the protein kinase C family also serve as major receptors for phorbol esters, a class of tumour promoters.
CAS REGISTRY NUMBER
COMMENTARY hide
141436-78-4
calcium-dependent protein kinase C
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
KPCB_DANRE
670
0
76306
Swiss-Prot
other Location (Reliability: 2)
KPCI_DANRE
588
0
67322
Swiss-Prot
other Location (Reliability: 3)
PKN2_DANRE
977
0
110657
Swiss-Prot
other Location (Reliability: 2)
A4QNX9_DANRE
909
0
103329
TrEMBL
other Location (Reliability: 1)
A0A8M1PFJ6_DANRE
684
0
77918
TrEMBL
other Location (Reliability: 3)
Q7ZUC5_DANRE
684
0
77918
TrEMBL
other Location (Reliability: 3)
A0A2R8RSZ2_DANRE
702
0
80442
TrEMBL
other Location (Reliability: 4)
A0A0R4IJZ0_DANRE
970
0
110346
TrEMBL
other Location (Reliability: 1)
B8A467_DANRE
738
0
84108
TrEMBL
other Location (Reliability: 3)
A0A8M1NIA8_DANRE
712
0
80428
TrEMBL
other Location (Reliability: 3)
A0A2R8Q5P7_DANRE
676
0
77449
TrEMBL
other Location (Reliability: 4)
Q7T2C5_DANRE
668
0
76120
TrEMBL
other Location (Reliability: 1)
B1H1I7_DANRE
712
0
80428
TrEMBL
other Location (Reliability: 3)
A0A2R8RKD1_DANRE
660
0
75198
TrEMBL
other Location (Reliability: 1)
X1WHC7_DANRE
886
0
99671
TrEMBL
other Location (Reliability: 5)
E7F4L5_DANRE
685
0
77900
TrEMBL
other Location (Reliability: 2)
A0A0R4IJB4_DANRE
977
0
110626
TrEMBL
other Location (Reliability: 2)
F6NV75_DANRE
930
0
105014
TrEMBL
other Location (Reliability: 1)
Q801L4_DANRE
412
0
46786
TrEMBL
other Location (Reliability: 2)
A0A2R8QJ48_DANRE
702
0
80671
TrEMBL
Mitochondrion (Reliability: 4)
E7FA73_DANRE
878
0
98856
TrEMBL
other Location (Reliability: 5)
E7F368_DANRE
744
0
84394
TrEMBL
other Location (Reliability: 3)
A0A8M1NE42_DANRE
713
0
81868
TrEMBL
other Location (Reliability: 3)
Q4JG04_DANRE
599
0
68749
TrEMBL
other Location (Reliability: 2)
A0A0R4IUK0_DANRE
625
0
71630
TrEMBL
Secretory Pathway (Reliability: 2)
B0S4T7_DANRE
599
0
68776
TrEMBL
other Location (Reliability: 2)
A9JTH6_DANRE
660
0
74799
TrEMBL
other Location (Reliability: 3)
F1QTL5_DANRE
709
0
81229
TrEMBL
other Location (Reliability: 1)
A0A2R8QDD3_DANRE
940
0
106183
TrEMBL
other Location (Reliability: 2)
Q5TZD4_DANRE
676
0
77677
TrEMBL
Mitochondrion (Reliability: 4)
E9QCG5_DANRE
929
0
104946
TrEMBL
other Location (Reliability: 1)
F1R444_DANRE
634
0
72517
TrEMBL
other Location (Reliability: 3)
A0A2R8RM45_DANRE
670
0
76418
TrEMBL
other Location (Reliability: 2)
A0A2R8RQU7_DANRE
964
0
109312
TrEMBL
other Location (Reliability: 1)
A0A2R8RL78_DANRE
984
0
111374
TrEMBL
other Location (Reliability: 3)
A0A2R8QFC7_DANRE
1005
0
114090
TrEMBL
other Location (Reliability: 1)
A0A2R8RJF1_DANRE
904
0
102031
TrEMBL
other Location (Reliability: 2)
A0A2R8QMW2_DANRE
670
0
76368
TrEMBL
other Location (Reliability: 2)
F1QJU6_DANRE
654
0
74184
TrEMBL
other Location (Reliability: 5)
E7F7I3_DANRE
940
0
106159
TrEMBL
other Location (Reliability: 2)
F1R506_DANRE
713
0
81868
TrEMBL
other Location (Reliability: 3)
A0A8M1NCL9_DANRE
339
0
38338
TrEMBL
other Location (Reliability: 2)
A0A2R8RW52_DANRE
562
0
63306
TrEMBL
other Location (Reliability: 1)
A0A2R8Q2S7_DANRE
921
0
104300
TrEMBL
other Location (Reliability: 1)
A0A2R8QIY5_DANRE
670
0
76273
TrEMBL
other Location (Reliability: 3)
E7F9Z2_DANRE
891
0
100402
TrEMBL
other Location (Reliability: 5)
A0A0R4IPY3_DANRE
635
0
72799
TrEMBL
Secretory Pathway (Reliability: 2)
Q6DI53_DANRE
588
0
67292
TrEMBL
other Location (Reliability: 3)