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Information on EC 2.7.10.1 - receptor protein-tyrosine kinase and Organism(s) Taeniopygia guttata

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EC Tree
IUBMB Comments
The receptor protein-tyrosine kinases, which can be defined as having a transmembrane domain, are a large and diverse multigene family found only in Metazoans . In the human genome, 58 receptor-type protein-tyrosine kinases have been identified and these are distributed into 20 subfamilies.
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This record set is specific for:
Taeniopygia guttata
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The taxonomic range for the selected organisms is: Taeniopygia guttata
The enzyme appears in selected viruses and cellular organisms
Synonyms
tyrosine kinase, epidermal growth factor receptor, insulin receptor, c-kit, erlotinib, c-met, erbb2, egf receptor, receptor tyrosine kinase, her-2, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Adhesion-related kinase
-
-
-
-
Anaplastic lymphoma kinase
-
-
-
-
AXL oncogene
-
-
-
-
Brain-specific kinase
-
-
-
-
Breathless protein
-
-
-
-
c-erbB3
-
-
-
-
c-fgr
-
-
-
-
c-fms
-
-
-
-
c-kit
-
-
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c-Kit tyrosine kinase
-
-
-
-
C-mer
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-
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c-met
-
-
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C-ret
-
-
-
-
C14
-
-
-
-
Cadherin 96Ca
-
-
-
-
CD115 antigen
-
-
-
-
CD117 antigen
-
-
-
-
CD135 antigen
-
-
-
-
CD136 antigen
-
-
-
-
CD140a antigen
-
-
-
-
CD140b antigen
-
-
-
-
CD167a antigen
-
-
-
-
CD202b antigen
-
-
-
-
CD220 antigen
-
-
-
-
CD221 antigen
-
-
-
-
CD246 antigen
-
-
-
-
CDW136
-
-
-
-
CEK4
-
-
-
-
Cell adhesion kinase
-
-
-
-
Derailed protein
-
-
-
-
DFGF-R1
-
-
-
-
Discoidin receptor tyrosine kinase
-
-
-
-
Doughnut protein
-
-
-
-
Dror
-
-
-
-
Drosophila relative of ERBB
-
-
-
-
DRT
-
-
-
-
EBK
-
-
-
-
EGF receptor tyrosine kinase
-
-
-
-
Egfr
-
-
-
-
EGFr TK
-
-
-
-
Egg laying defective protein 15
-
-
-
-
ELK
-
-
-
-
Embryonic brain kinase
-
-
-
-
Endothelial kinase receptor EK1
-
-
-
-
EPH-and ELK-related kinase
-
-
-
-
Epidermal growth factor receptor-related protein
-
-
-
-
Epithelial cell kinase
-
-
-
-
erbB tyrosine kinase
-
-
-
-
ErbB2 kinase
-
-
-
-
ERK
-
-
-
-
ETK
-
-
-
-
Fms proto-oncogene
-
-
-
-
GCTK
-
-
-
-
GP145-TrkB
-
-
-
-
GP145-TrkB/GP95-TrkB
-
-
-
-
GP145-TrkC
-
-
-
-
Gurken receptor
-
-
-
-
Heartless protein
-
-
-
-
HEK
-
-
-
-
HEK3
-
-
-
-
HEK4
-
-
-
-
HEK6
-
-
-
-
Heparin-binding growth factor receptor
-
-
-
-
HGF receptor
-
-
-
-
HGF-SF receptor
-
-
-
-
hydroxyaryl-protein kinase
-
-
-
-
HYK
-
-
-
-
ILP receptor
-
-
-
-
insulin receptor protein-tyrosine kinase
-
-
-
-
IR-related receptor
-
-
-
-
IRK
-
-
-
-
IRR
-
-
-
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Keratinocyte growth factor receptor
-
-
-
-
Kinase insert domain receptor
-
-
-
-
Kinase NYK
-
-
-
-
Kinase VIK
-
-
-
-
Linotte protein
-
-
-
-
MEK4
-
-
-
-
Met proto-oncogene tyrosine kinase
-
-
-
-
Met-related kinase
-
-
-
-
MFR
-
-
-
-
MIR
-
-
-
-
MLN 19
-
-
-
-
mROR1
-
-
-
-
mROR2
-
-
-
-
MSP receptor
-
-
-
-
NET
-
-
-
-
NEU proto-oncogene
-
-
-
-
Neurospecific receptor tyrosine kinase
-
-
-
-
NRTK
-
-
-
-
NUK
-
-
-
-
P140 TEK
-
-
-
-
p140-TrkA
-
-
-
-
p180erbB4
-
-
-
-
p185-Ron
-
-
-
-
p185erbB2
-
-
-
-
Pagliaccio
-
-
-
-
PDGF-R-alpha
-
-
-
-
PDGF-R-beta
-
-
-
-
PDGFR kinase
-
-
-
-
Protein-tyrosine kinase byk
-
-
-
-
Protein-tyrosine kinase receptor MPK-11
-
-
-
-
Proto-oncogene tyrosine-protein kinase Kit
-
-
-
-
Receptor protein-tyrosine kinase HEK11
-
-
-
-
Receptor protein-tyrosine kinase HEK5
-
-
-
-
Receptor protein-tyrosine kinase HEK7
-
-
-
-
Receptor protein-tyrosine kinase HEK8
-
-
-
-
Receptor protein-tyrosine kinase TKT
-
-
-
-
Receptor tyrosine kinase MerTK
-
-
-
-
Receptor-activated Janus kinase
-
-
-
-
RTK
-
-
-
-
SCFR
-
-
-
-
Slow nerve growth factor receptor
-
-
-
-
Stem cell-derived tyrosine kinase
-
-
-
-
Torpedo protein
-
-
-
-
TRK1 transforming tyrosine kinase protein
-
-
-
-
TrkB tyrosine kinase
-
-
-
-
TrkC tyrosine kinase
-
-
-
-
Tunica interna endothelial cell kinase
-
-
-
-
Tyrosine kinase CEK6 receptor
-
-
-
-
Tyrosine kinase DDR
-
-
-
-
Tyrosine kinase receptor HD-14
-
-
-
-
Tyrosine kinase-type cell surface receptor HER2
-
-
-
-
Tyrosine kinase-type cell surface receptor HER3
-
-
-
-
Tyrosine kinase-type cell surface receptor HER4
-
-
-
-
Tyrosine-protein kinase CAK
-
-
-
-
Tyrosine-protein kinase CEK9
-
-
-
-
Tyrosine-protein kinase DTK
-
-
-
-
Tyrosine-protein kinase FLT3
-
-
-
-
Tyrosine-protein kinase FRT
-
-
-
-
Tyrosine-protein kinase receptor CEK10
-
-
-
-
Tyrosine-protein kinase receptor CEK11
-
-
-
-
Tyrosine-protein kinase receptor CEK5
-
-
-
-
Tyrosine-protein kinase receptor CEK7
-
-
-
-
Tyrosine-protein kinase receptor CEK8
-
-
-
-
Tyrosine-protein kinase receptor CEPHA7
-
-
-
-
Tyrosine-protein kinase receptor ECK
-
-
-
-
Tyrosine-protein kinase receptor EEK
-
-
-
-
Tyrosine-protein kinase receptor EPH
-
-
-
-
Tyrosine-protein kinase receptor ESK
-
-
-
-
Tyrosine-protein kinase receptor ETK1
-
-
-
-
Tyrosine-protein kinase receptor FLT
-
-
-
-
Tyrosine-protein kinase receptor FLT3
-
-
-
-
Tyrosine-protein kinase receptor FLT4
-
-
-
-
Tyrosine-protein kinase receptor HTK
-
-
-
-
Tyrosine-protein kinase receptor PAG
-
-
-
-
Tyrosine-protein kinase receptor QEK5
-
-
-
-
Tyrosine-protein kinase receptor REK4
-
-
-
-
Tyrosine-protein kinase receptor SEK
-
-
-
-
Tyrosine-protein kinase receptor TCK
-
-
-
-
Tyrosine-protein kinase receptor TEK
-
-
-
-
Tyrosine-protein kinase receptor XEK
-
-
-
-
Tyrosine-protein kinase receptor XELK
-
-
-
-
Tyrosine-protein kinase receptor ZEK1
-
-
-
-
Tyrosine-protein kinase receptor ZEK2
-
-
-
-
Tyrosine-protein kinase receptor ZEK3
-
-
-
-
Tyrosine-protein kinase RSE
-
-
-
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Tyrosine-protein kinase SKY
-
-
-
-
Vascular permeability factor receptor
-
-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
phospho group transfer
-
-
-
-
SYSTEMATIC NAME
IUBMB Comments
ATP:[protein]-L-tyrosine O-phosphotransferase (receptor-type)
The receptor protein-tyrosine kinases, which can be defined as having a transmembrane domain, are a large and diverse multigene family found only in Metazoans [1]. In the human genome, 58 receptor-type protein-tyrosine kinases have been identified and these are distributed into 20 subfamilies.
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
A0A674HIB2_TAEGU
896
1
98363
TrEMBL
other Location (Reliability: 4)
A0A674H6Q0_TAEGU
1121
0
121593
TrEMBL
Secretory Pathway (Reliability: 2)
A0A674H5B1_TAEGU
1077
2
119899
TrEMBL
Secretory Pathway (Reliability: 1)
A0A674GNM7_TAEGU
852
2
95901
TrEMBL
Secretory Pathway (Reliability: 1)
A0A674GKQ0_TAEGU
1255
2
137087
TrEMBL
other Location (Reliability: 2)
H0ZBL7_TAEGU
964
2
107565
TrEMBL
Secretory Pathway (Reliability: 1)
A0A674HGW1_TAEGU
967
1
108036
TrEMBL
Mitochondrion (Reliability: 5)
A0A674HQB3_TAEGU
1117
1
124197
TrEMBL
other Location (Reliability: 2)
A0A674GCU0_TAEGU
826
2
93200
TrEMBL
Secretory Pathway (Reliability: 1)
H0ZJI7_TAEGU
991
1
110177
TrEMBL
Secretory Pathway (Reliability: 1)
H0ZK19_TAEGU
794
1
88453
TrEMBL
Mitochondrion (Reliability: 4)
A0A674G966_TAEGU
855
0
95064
TrEMBL
Secretory Pathway (Reliability: 5)
H0Z3P7_TAEGU
1419
2
155715
TrEMBL
Secretory Pathway (Reliability: 1)
H0Z5K6_TAEGU
1311
0
147325
TrEMBL
Secretory Pathway (Reliability: 1)
A0A674GQU1_TAEGU
1022
2
115475
TrEMBL
Secretory Pathway (Reliability: 1)
A0A674GTG8_TAEGU
855
1
96868
TrEMBL
Secretory Pathway (Reliability: 3)
H1A3E4_TAEGU
843
1
94943
TrEMBL
Secretory Pathway (Reliability: 2)
A0A674GDN0_TAEGU
993
1
111324
TrEMBL
Secretory Pathway (Reliability: 2)
A0A674HPH6_TAEGU
1940
1
218557
TrEMBL
other Location (Reliability: 4)
A0A674HUV7_TAEGU
907
0
100843
TrEMBL
Secretory Pathway (Reliability: 5)
H0ZSP2_TAEGU
962
1
107936
TrEMBL
Secretory Pathway (Reliability: 1)
A0A674GMC8_TAEGU
1304
1
144238
TrEMBL
Mitochondrion (Reliability: 3)
H0Z2T4_TAEGU
947
1
104760
TrEMBL
Secretory Pathway (Reliability: 5)
H0ZEE4_TAEGU
1363
2
154073
TrEMBL
Secretory Pathway (Reliability: 1)
A0A674HRE1_TAEGU
911
1
102132
TrEMBL
Secretory Pathway (Reliability: 2)
H0ZW24_TAEGU
699
2
79480
TrEMBL
Secretory Pathway (Reliability: 2)
A0A674GZZ1_TAEGU
1234
2
138745
TrEMBL
other Location (Reliability: 2)
A0A674H1Z3_TAEGU
833
1
92767
TrEMBL
Secretory Pathway (Reliability: 5)
A0A674HAZ4_TAEGU
1103
1
122649
TrEMBL
other Location (Reliability: 5)
A0A674HFK0_TAEGU
1067
2
120786
TrEMBL
Secretory Pathway (Reliability: 1)
H0YT27_TAEGU
1117
1
125009
TrEMBL
Secretory Pathway (Reliability: 3)
A0A674GVZ0_TAEGU
1505
0
164422
TrEMBL
Mitochondrion (Reliability: 2)
A0A674HUF9_TAEGU
1141
1
126101
TrEMBL
other Location (Reliability: 3)
A0A674H6L7_TAEGU
819
2
92388
TrEMBL
Secretory Pathway (Reliability: 1)
H0YU95_TAEGU
1222
2
135559
TrEMBL
Secretory Pathway (Reliability: 4)
A0A674GTH9_TAEGU
1022
1
112093
TrEMBL
other Location (Reliability: 2)
A0A674GG79_TAEGU
739
1
81240
TrEMBL
other Location (Reliability: 4)
H0Z7B3_TAEGU
1104
0
125104
TrEMBL
Secretory Pathway (Reliability: 2)
A0A674GRW1_TAEGU
1316
0
147272
TrEMBL
other Location (Reliability: 4)
A0A674GTQ3_TAEGU
1193
0
133317
TrEMBL
other Location (Reliability: 5)
A0A674G7P0_TAEGU
842
1
93128
TrEMBL
other Location (Reliability: 2)
A0A674GAW5_TAEGU
905
1
99768
TrEMBL
Mitochondrion (Reliability: 4)
A0A674GU57_TAEGU
1032
1
115519
TrEMBL
other Location (Reliability: 2)
A0A674GBZ6_TAEGU
951
1
105074
TrEMBL
other Location (Reliability: 4)
H0ZQ33_TAEGU
1020
1
114842
TrEMBL
Secretory Pathway (Reliability: 2)
A0A674H9Q0_TAEGU
1020
0
112971
TrEMBL
Secretory Pathway (Reliability: 5)
A0A674G7V3_TAEGU
1019
3
116407
TrEMBL
Secretory Pathway (Reliability: 2)
H0Z9U6_TAEGU
1124
2
124950
TrEMBL
Secretory Pathway (Reliability: 1)
H0YQ95_TAEGU
849
0
95253
TrEMBL
other Location (Reliability: 5)
A0A674GF60_TAEGU
982
1
108072
TrEMBL
other Location (Reliability: 5)
A0A674GQN9_TAEGU
1137
1
123497
TrEMBL
other Location (Reliability: 2)
H0ZKX9_TAEGU
872
1
96331
TrEMBL
Secretory Pathway (Reliability: 1)
H0ZNV1_TAEGU
2231
1
250765
TrEMBL
other Location (Reliability: 3)
H1A3R4_TAEGU
984
1
109635
TrEMBL
Secretory Pathway (Reliability: 1)
H0Z3I3_TAEGU
820
1
91781
TrEMBL
Secretory Pathway (Reliability: 1)
A0A674HIV0_TAEGU
2290
1
257538
TrEMBL
Secretory Pathway (Reliability: 1)
A0A674H8A5_TAEGU
1102
3
124549
TrEMBL
Secretory Pathway (Reliability: 1)
A0A674HJ27_TAEGU
1027
1
116072
TrEMBL
Mitochondrion (Reliability: 2)
A0A674H6Z3_TAEGU
758
1
84126
TrEMBL
Secretory Pathway (Reliability: 1)
A0A674H9A4_TAEGU
934
1
104177
TrEMBL
other Location (Reliability: 1)
A0A674GAI7_TAEGU
865
0
95317
TrEMBL
other Location (Reliability: 5)
D8UWE3_TAEGU
967
2
107701
TrEMBL
Secretory Pathway (Reliability: 1)
A0A674H8S1_TAEGU
1179
1
132757
TrEMBL
Mitochondrion (Reliability: 3)
H0YRT7_TAEGU
964
2
107457
TrEMBL
Secretory Pathway (Reliability: 1)
H1A435_TAEGU
1323
0
147593
TrEMBL
other Location (Reliability: 2)
A0A674H987_TAEGU
1000
1
111535
TrEMBL
Secretory Pathway (Reliability: 3)
H0ZMM7_TAEGU
1244
2
140002
TrEMBL
other Location (Reliability: 2)
A0A674H2J3_TAEGU
1340
2
149179
TrEMBL
Secretory Pathway (Reliability: 1)
A0A674HNM8_TAEGU
1363
1
150341
TrEMBL
other Location (Reliability: 2)
H0ZAR8_TAEGU
963
1
106266
TrEMBL
other Location (Reliability: 5)
A0A674HUG7_TAEGU
1113
0
120108
TrEMBL
other Location (Reliability: 2)
H0ZKT0_TAEGU
1467
0
160341
TrEMBL
Mitochondrion (Reliability: 2)
A0A674HDN8_TAEGU
798
0
89104
TrEMBL
other Location (Reliability: 2)
H1A3Q0_TAEGU
964
1
107473
TrEMBL
other Location (Reliability: 2)
A0A674G701_TAEGU
2276
2
256706
TrEMBL
Secretory Pathway (Reliability: 4)
A0A674GDQ0_TAEGU
1336
1
146299
TrEMBL
other Location (Reliability: 2)
A0A674GIR8_TAEGU
2162
0
243478
TrEMBL
Secretory Pathway (Reliability: 4)
H0YQ96_TAEGU
1323
1
149581
TrEMBL
other Location (Reliability: 3)
A0A674G9N3_TAEGU
1296
0
142656
TrEMBL
other Location (Reliability: 2)
A0A674HKX7_TAEGU
935
1
104230
TrEMBL
Secretory Pathway (Reliability: 1)
H0YST1_TAEGU
938
1
104231
TrEMBL
Secretory Pathway (Reliability: 1)
H0ZSI9_TAEGU
998
1
111320
TrEMBL
Secretory Pathway (Reliability: 3)
H0ZBM3_TAEGU
1011
1
112114
TrEMBL
Mitochondrion (Reliability: 4)
Q6B515_TAEGU
669
1
74750
TrEMBL
other Location (Reliability: 2)
H0ZBR5_TAEGU
1085
2
122574
TrEMBL
Secretory Pathway (Reliability: 1)
A0A674G9W9_TAEGU
1201
2
133720
TrEMBL
other Location (Reliability: 4)
A0A674HNT1_TAEGU
1303
1
143759
TrEMBL
other Location (Reliability: 4)
A0A674H262_TAEGU
1268
1
139434
TrEMBL
other Location (Reliability: 3)
A0A674HIN2_TAEGU
1312
1
144455
TrEMBL
other Location (Reliability: 2)
A0A674GCA7_TAEGU
160
0
18497
TrEMBL
Secretory Pathway (Reliability: 4)
H0Z494_TAEGU
1385
1
155315
TrEMBL
Secretory Pathway (Reliability: 2)
H0ZN34_TAEGU
1325
0
148324
TrEMBL
Secretory Pathway (Reliability: 2)
H0ZN05_TAEGU
959
3
109595
TrEMBL
Secretory Pathway (Reliability: 2)
H0Z935_TAEGU
1003
1
111489
TrEMBL
Secretory Pathway (Reliability: 1)
A0A674H7D4_TAEGU
499
1
56174
TrEMBL
other Location (Reliability: 2)
A0A674G940_TAEGU
1089
1
122853
TrEMBL
Secretory Pathway (Reliability: 1)
A0A674GVD1_TAEGU
1318
1
145298
TrEMBL
other Location (Reliability: 3)
H0YY17_TAEGU
808
1
90161
TrEMBL
Secretory Pathway (Reliability: 1)
A0A674GZV9_TAEGU
1312
1
144210
TrEMBL
other Location (Reliability: 2)
A0A674GDW7_TAEGU
1236
2
138136
TrEMBL
other Location (Reliability: 3)
A0A674GQJ1_TAEGU
1325
1
145336
TrEMBL
other Location (Reliability: 2)
A0A674H7M5_TAEGU
1109
3
125260
TrEMBL
Secretory Pathway (Reliability: 5)
A0A674GFH4_TAEGU
842
1
93734
TrEMBL
Secretory Pathway (Reliability: 1)
H0ZBE3_TAEGU
1340
2
149275
TrEMBL
other Location (Reliability: 2)
A0A674H0U0_TAEGU
911
1
101681
TrEMBL
other Location (Reliability: 3)
H0ZLZ4_TAEGU
775
1
87038
TrEMBL
other Location (Reliability: 3)
H0ZDH2_TAEGU
849
1
95804
TrEMBL
Secretory Pathway (Reliability: 2)
A0A674HMT5_TAEGU
995
1
110746
TrEMBL
Secretory Pathway (Reliability: 1)
A0A674GXB5_TAEGU
1218
1
137108
TrEMBL
other Location (Reliability: 2)
A0A674HMQ7_TAEGU
1232
1
135851
TrEMBL
other Location (Reliability: 3)
H0YV01_TAEGU
1004
1
110851
TrEMBL
Mitochondrion (Reliability: 4)
H0YX36_TAEGU
873
1
99295
TrEMBL
Secretory Pathway (Reliability: 3)
A0A674H0K6_TAEGU
923
1
102930
TrEMBL
Secretory Pathway (Reliability: 1)
A0A674G964_TAEGU
1306
1
144348
TrEMBL
Mitochondrion (Reliability: 3)
A0A674GXC2_TAEGU
827
2
92937
TrEMBL
Secretory Pathway (Reliability: 2)
A0A674GGQ2_TAEGU
1321
0
147352
TrEMBL
other Location (Reliability: 3)
H0ZTE5_TAEGU
937
1
104802
TrEMBL
other Location (Reliability: 1)
H0YRX0_TAEGU
1379
1
156380
TrEMBL
Secretory Pathway (Reliability: 1)
A0A674GU34_TAEGU
891
1
99821
TrEMBL
Secretory Pathway (Reliability: 2)
A0A674GT12_TAEGU
2275
1
256621
TrEMBL
Mitochondrion (Reliability: 5)
H0YRS6_TAEGU
1092
1
123153
TrEMBL
Secretory Pathway (Reliability: 1)