Information on EC 2.7.1.74 - deoxycytidine kinase

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The expected taxonomic range for this enzyme is: Eukaryota, Bacteria

EC NUMBER
COMMENTARY
2.7.1.74
-
RECOMMENDED NAME
GeneOntology No.
deoxycytidine kinase
REACTION TYPE
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
phospho group transfer
-
-
-
-
PATHWAY
KEGG Link
MetaCyc Link
Metabolic pathways
-
purine deoxyribonucleosides salvage
-
Purine metabolism
-
pyrimidine deoxyribonucleosides salvage
-
Pyrimidine metabolism
-
SYSTEMATIC NAME
IUBMB Comments
NTP:deoxycytidine 5'-phosphotransferase
Cytosine arabinoside can act as acceptor; all natural nucleoside triphosphates (except dCTP) can act as donors.
SYNONYMS
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
2'-deoxycytidine kinase
-
-
-
-
ara-C kinase
-
-
-
-
arabinofuranosylcytosine kinase
-
-
-
-
dC kinase
-
-
dC kinase
Bacillus megaterium KM
-
-
-
dCK
-
-
-
-
dCK
P43346
-
dCK
Mus musculus C57BL/6J
-
-
-
deoxycytidine kinase
-
-
deoxycytidine-cytidine kinase
-
-
-
-
dNTP:deoxycytidine 5'-phosphotransferase
-
-
kinase, deoxycytidine (phosphorylating)
-
-
-
-
NTP:deoxycytidine 5'-phosphotransferase
P27707
-
CAS REGISTRY NUMBER
COMMENTARY
9039-45-6
-
ORGANISM
COMMENTARY
LITERATURE
SEQUENCE CODE
SEQUENCE DB
SOURCE
owl monkey
-
-
Manually annotated by BRENDA team
strain KM
-
-
Manually annotated by BRENDA team
Bacillus megaterium KM
strain KM
-
-
Manually annotated by BRENDA team
; patients with B-cell chronic lymphocytic leukaemia
-
-
Manually annotated by BRENDA team
B-CLL patients
-
-
Manually annotated by BRENDA team
differences in mRNA levels in African and European individuals detected
-
-
Manually annotated by BRENDA team
patients suffering from pancreatic cancer, survival of patients is found to be correlated to the detected enzyme level
-
-
Manually annotated by BRENDA team
patients with pancreatic cancer
-
-
Manually annotated by BRENDA team
-
SwissProt
Manually annotated by BRENDA team
Ada-/- mice
-
-
Manually annotated by BRENDA team
Mus musculus C57BL/6J
-
-
-
Manually annotated by BRENDA team
PDB
SCOP
CATH
ORGANISM
pH STABILITY
pH STABILITY MAXIMUM
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
6
-
-
t1/2: 2 min at 60°C
8
-
-
moderately stable, t1/2: 7.9 min at 60°C
10
-
-
unstable at 60°C