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Information on EC 2.7.1.68 - 1-phosphatidylinositol-4-phosphate 5-kinase and Organism(s) Drosophila melanogaster

for references in articles please use BRENDA:EC2.7.1.68
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EC Tree
IUBMB Comments
This enzyme can also phosphorylate PtdIns3P in the 4-position, and PtdIns, PtdIns3P and PtdIns(3,4)P2 in the 5-position in vitro, but to a lesser extent. The last of these reactions occurs in vivo and is physiologically relevant. Three different isoforms are known.
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This record set is specific for:
Drosophila melanogaster
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Word Map
The taxonomic range for the selected organisms is: Drosophila melanogaster
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Synonyms
pipkin, pip5k, pip kinase, ptdinsp, phosphatidylinositol 4-phosphate 5-kinase, phosphatidylinositol-4-phosphate 5-kinase, pipk, pipkigamma, pip5ks, pip5k1a, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Diphosphoinositide kinase
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MSS4p
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phosphatidylinositol 4-phosphate kinase
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phosphatidylinositol-4-phosphate 5-kinase
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PI4P 5-kinase
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PI4P5K
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PIP kinase
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PIP-5kin
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PIP5K
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PIP5Ks
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PtdIns(4)P 5-kinase
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
phospho group transfer
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PATHWAY SOURCE
PATHWAYS
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-, -
SYSTEMATIC NAME
IUBMB Comments
ATP:1-phosphatidyl-1D-myo-inositol-4-phosphate 5-phosphotransferase
This enzyme can also phosphorylate PtdIns3P in the 4-position, and PtdIns, PtdIns3P and PtdIns(3,4)P2 in the 5-position in vitro, but to a lesser extent. The last of these reactions occurs in vivo and is physiologically relevant. Three different isoforms are known.
CAS REGISTRY NUMBER
COMMENTARY hide
104645-76-3
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9032-61-5
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UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
Q9W1Y2_DROME
729
0
80239
TrEMBL
other Location (Reliability: 1)
A0A0B4K7M0_DROME
756
0
83149
TrEMBL
other Location (Reliability: 1)
A0A6M3Q9L5_DROME
891
0
99021
TrEMBL
other Location (Reliability: 1)
Q9W1Y3_DROME
750
0
82696
TrEMBL
other Location (Reliability: 1)
Q0E8Y1_DROME
781
0
86054
TrEMBL
other Location (Reliability: 1)
A0A0B4K7E3_DROME
777
0
85606
TrEMBL
other Location (Reliability: 1)
Q9W2R3_DROME
792
0
87758
TrEMBL
other Location (Reliability: 1)