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Information on EC 2.7.1.32 - choline kinase and Organism(s) Arabidopsis thaliana

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EC Tree
IUBMB Comments
Ethanolamine and its methyl and ethyl derivatives can also act as acceptors.
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This record set is specific for:
Arabidopsis thaliana
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Word Map
The taxonomic range for the selected organisms is: Arabidopsis thaliana
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
Synonyms
choline kinase, choline kinase alpha, chokalpha, choline kinase beta, choline/ethanolamine kinase, chk-alpha, chokalpha1, schok, ck-alpha, choline kinase-alpha, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
CHETK-alpha
-
-
-
-
ChoK
-
-
-
-
choline phosphokinase
-
-
-
-
choline-ethanolamine kinase
-
-
-
-
choline/ethanolamine kinase
-
-
-
-
choline/ethanolamine kinase 1
-
choline/ethanolamine kinase 2
-
choline/ethanolamine kinase 3
-
ER-localized Cho kinase
-
EtnK
-
-
-
-
kinase, choline (phosphorylating)
-
-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
phospho group transfer
-
-
-
-
PATHWAY SOURCE
PATHWAYS
-
-, -, -, -
SYSTEMATIC NAME
IUBMB Comments
ATP:choline phosphotransferase
Ethanolamine and its methyl and ethyl derivatives can also act as acceptors.
CAS REGISTRY NUMBER
COMMENTARY hide
9026-67-9
-
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
ATP + choline
ADP + O-phosphocholine
show the reaction diagram
ATP + choline
ADP + phosphocholine
show the reaction diagram
-
-
-
?
additional information
?
-
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
ATP + choline
ADP + O-phosphocholine
show the reaction diagram
-
initial step of the Kennedy pathway, that yields phosphatidylcholine as final product, increased activity under salt stress and cold conditions
-
-
?
ATP + choline
ADP + phosphocholine
show the reaction diagram
-
-
-
?
METALS and IONS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
TEMPERATURE OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
CEK1 is highly expressed in the root tips of germinating seedlings at days 1-4
Manually annotated by BRENDA team
additional information
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
evolution
in Arabidopsis thaliana, the CEK family consists of four isoforms. Isozymes in this family may phosphorylate choline (Cho kinase, EC 2.7.1.32) or ethanolamine (Etn kinase, EC 2.7.1.82) in the presence of ATP and magnesium ions, producing phosphocholine (PCho) or phosphoethanolamine (PEtn), respectively
malfunction
physiological function
additional information
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
CK2_ARATH
350
0
41017
Swiss-Prot
other Location (Reliability: 2)
CK3_ARATH
346
0
40351
Swiss-Prot
other Location (Reliability: 3)
CK1_ARATH
346
0
40016
Swiss-Prot
other Location (Reliability: 4)
PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
gene CK1, recombinant overexpression in Arabidopsis thaliana plants via Agrobacterium tumefaciens-mediated transformation, quantitative RT-PCR enzyme expression analysis at normal or tunicamycin (Tm)-induced endoplasmic reticulum (ER) stress conditions
locus At1g74320, recombinant overexpression in Arabidopsis thaliana plants via Agrobacterium tumefaciens-mediated transformation, quantitative RT-PCR enzyme expression analysis at normal or tunicamycin (Tm)-induced endoplasmic reticulum (ER) stress conditions
locus At4g09760, recombinant overexpression in Arabidopsis thaliana plants via Agrobacterium tumefaciens-mediated transformation, quantitative RT-PCR enzyme expression analysis at normal or tunicamycin (Tm)-induced endoplasmic reticulum (ER) stress conditions
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Tasseva, G.; Richard, L.; Zachowski, A.
Regulation of phosphatidylcholine biosynthesis under salt stress involves choline kinases in Arabidopsis thaliana
FEBS Lett.
566
115-120
2004
Arabidopsis thaliana
Manually annotated by BRENDA team
Lin, Y.C.; Kanehara, K.; Nakamura, Y.
Arabidopsis CHOLINE/ETHANOLAMINE KINASE 1 (CEK1) is a primary choline kinase localized at the endoplasmic reticulum (ER) and involved in ER stress tolerance
New Phytol.
223
1904-1917
2019
Arabidopsis thaliana (Q8L518), Arabidopsis thaliana (Q9M9H6), Arabidopsis thaliana (Q9SZ92), Arabidopsis thaliana Col-0 (Q8L518), Arabidopsis thaliana Col-0 (Q9M9H6), Arabidopsis thaliana Col-0 (Q9SZ92)
Manually annotated by BRENDA team