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Information on EC 2.7.1.150 - 1-phosphatidylinositol-3-phosphate 5-kinase and Organism(s) Drosophila melanogaster

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This record set is specific for:
Drosophila melanogaster
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The taxonomic range for the selected organisms is: Drosophila melanogaster
The enzyme appears in selected viruses and cellular organisms
Synonyms
pikfyve, ste12, fab1p, pip5k3, fab1/pikfyve, phosphatidylinositol 3-phosphate 5-kinase, ppk-3, phosphatidylinositol-3-phosphate-5-kinase pikfyve, ptdins3p 5-kinase, cgfab1, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Fab1p
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kinase (phosphorylating), phosphatidylinositol 3-phosphate 5-
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phosphatidylinositol 3-phosphate 5-kinase
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phosphatidylinositol 5-OH kinase
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Phosphatidylinositol-3-phosphate 5-kinase
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PI(3)P-5-kinase
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PtdIns(3) 5-kinase
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PtdIns3P 5-OH kinase
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type III PIP kinase
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additional information
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the enzyme belongs to the type III PIPkin family
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
phospho-group transfer
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PATHWAY SOURCE
PATHWAYS
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SYSTEMATIC NAME
IUBMB Comments
ATP:1-phosphatidyl-1D-myo-inositol-3-phosphate 5-phosphotransferase
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CAS REGISTRY NUMBER
COMMENTARY hide
190606-24-7
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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
ATP + 1-phosphatidyl-1D-myo-inositol 3-phosphate
ADP + 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate
show the reaction diagram
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?
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
ATP + 1-phosphatidyl-1D-myo-inositol 3-phosphate
ADP + 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate
show the reaction diagram
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?
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
FYV1_DROME
1809
0
204635
Swiss-Prot
Mitochondrion (Reliability: 5)
C7LAB6_DROME
1809
0
204635
TrEMBL
Mitochondrion (Reliability: 5)
SUBUNIT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
additional information
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the PIPkin type III family enzyme consists of 4 typical domains: the FYVE RING Zn-finger domain, the TCP-I/chaperone-like domain, the PIPkin domain, and the cysteine-rich domain, the fly enzyme contains additionally a DEP domain
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Cooke, F.T.
Phosphatidylinositol 3,5-bisphosphate: metabolism and function
Arch. Biochem. Biophys.
407
143-151
2002
Arabidopsis thaliana, Caenorhabditis elegans, Candida albicans, Drosophila melanogaster, Homo sapiens, Mus musculus, Oryza sativa, Schizosaccharomyces pombe, Saccharomyces cerevisiae (P34756)
Manually annotated by BRENDA team