Information on EC 2.6.1.94 - 2'-deamino-2'-hydroxyneamine transaminase

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The expected taxonomic range for this enzyme is: Streptomyces kanamyceticus

EC NUMBER
COMMENTARY
2.6.1.94
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RECOMMENDED NAME
GeneOntology No.
2'-deamino-2'-hydroxyneamine transaminase
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REACTION
REACTION DIAGRAM
COMMENTARY
ORGANISM
UNIPROT
LITERATURE
2'-deamino-2'-hydroxyneamine + 2-oxoglutarate = 2'-deamino-2'-hydroxy-6'-dehydroparomamine + L-glutamate
show the reaction diagram
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PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
Biosynthesis of antibiotics
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Butirosin and neomycin biosynthesis
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kanamycin biosynthesis
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SYSTEMATIC NAME
IUBMB Comments
2'-deamino-2'-hydroxyneamine:2-oxoglutarate aminotransferase
The reaction occurs in vivo in the opposite direction. Involved in the biosynthetic pathway of kanamycin A and kanamycin D. The enzyme, characterized from the bacterium Streptomyces kanamyceticus, can also catalyse EC 2.6.1.93, neamine transaminase.
ORGANISM
COMMENTARY
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
SUBSTRATE
PRODUCT                      
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
LITERATURE
(Substrate)
COMMENTARY
(Product)
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
2'-deamino-2'-hydroxyparomamine + L-glutamate
2'-deamino-2'-hydroxyneamine + 2-oxoglutarate
show the reaction diagram
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?
Cloned/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
expressed in Streptomyces venezuelae strain PAR
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