Information on EC 2.6.1.94 - 2'-deamino-2'-hydroxyneamine transaminase

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The expected taxonomic range for this enzyme is: Streptomyces kanamyceticus

EC NUMBER
COMMENTARY
2.6.1.94
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RECOMMENDED NAME
GeneOntology No.
2'-deamino-2'-hydroxyneamine transaminase
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REACTION
REACTION DIAGRAM
COMMENTARY
ORGANISM
UNIPROT ACCESSION NO.
LITERATURE
2'-deamino-2'-hydroxyneamine + 2-oxoglutarate = 2'-deamino-2'-hydroxy-6'-dehydroparomamine + L-glutamate
show the reaction diagram
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PATHWAY
KEGG Link
MetaCyc Link
Biosynthesis of secondary metabolites
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Butirosin and neomycin biosynthesis
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kanamycin biosynthesis
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SYSTEMATIC NAME
IUBMB Comments
2'-deamino-2'-hydroxyneamine:2-oxoglutarate aminotransferase
The reaction occurs in vivo in the opposite direction. Involved in the biosynthetic pathway of kanamycin A and kanamycin D. The enzyme, characterized from the bacterium Streptomyces kanamyceticus, can also catalyse EC 2.6.1.93, neamine transaminase.
SYNONYMS
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
6'-oxoparomamine aminotransferase
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kacL
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gene name
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ORGANISM
COMMENTARY
LITERATURE
SEQUENCE CODE
SEQUENCE DB
SOURCE
SUBSTRATE
PRODUCT                      
REACTION DIAGRAM
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
(Substrate)
LITERATURE
(Substrate)
COMMENTARY
(Product)
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
2'-deamino-2'-hydroxyparomamine + L-glutamate
2'-deamino-2'-hydroxyneamine + 2-oxoglutarate
show the reaction diagram
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?
Cloned/COMMENTARY
ORGANISM
UNIPROT ACCESSION NO.
LITERATURE
expressed in Streptomyces venezuelae strain PAR
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