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Information on EC 2.6.1.63 - kynurenine-glyoxylate transaminase and Organism(s) Homo sapiens

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EC Tree
     2 Transferases
         2.6 Transferring nitrogenous groups
             2.6.1 Transaminases
                2.6.1.63 kynurenine-glyoxylate transaminase
IUBMB Comments
This enzyme, characterized from animals, belongs to a family of aminotransferases some members of which can use other amino acceptors (cf. EC 2.6.1.7, kynurenine---oxoglutarate transaminase). The products, 4-(2-aminophenyl)-2,4-dioxobutanoate and 4-(2-amino-3-hydroxyphenyl)-2,4-dioxobutanoate, are converted to kynurenate and xanthurenate, respectively, by spontaneous reactions.
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Homo sapiens
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The taxonomic range for the selected organisms is: Homo sapiens
The enzyme appears in selected viruses and cellular organisms
Synonyms
3-hydroxykynurenine transaminase, 3-hkt, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
aminotransferase, kynurenine-glyoxylate
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
amino group transfer
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SYSTEMATIC NAME
IUBMB Comments
L-kynurenine:glyoxylate aminotransferase (cyclizing)
This enzyme, characterized from animals, belongs to a family of aminotransferases some members of which can use other amino acceptors (cf. EC 2.6.1.7, kynurenine---oxoglutarate transaminase). The products, 4-(2-aminophenyl)-2,4-dioxobutanoate and 4-(2-amino-3-hydroxyphenyl)-2,4-dioxobutanoate, are converted to kynurenate and xanthurenate, respectively, by spontaneous reactions.
CAS REGISTRY NUMBER
COMMENTARY hide
74506-33-5
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UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
AADAT_HUMAN
425
0
47352
Swiss-Prot
Mitochondrion (Reliability: 3)
KAT3_HUMAN
454
0
51400
Swiss-Prot
Mitochondrion (Reliability: 2)
B4DW13_HUMAN
454
0
51400
TrEMBL
Mitochondrion (Reliability: 2)
A0A0A0MRN7_HUMAN
262
0
29471
TrEMBL
Mitochondrion (Reliability: 2)