Reference on EC 2.6.1.52 - phosphoserine transaminase
Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Hirsch, H.; Greenberg, D.M.
Studies on phosphoserine aminotransferase of sheep brain
J. Biol. Chem.
242
2283-2287
1967
Ovis aries
Hirsch-Kolb, H.; Greenberg, D.M.
Phosphoserine aminotransferase (sheep brain)
Methods Enzymol.
17B
331-334
1971
Ovis aries
-
Lund, K.; Merrill, D.K.; Guynn, R.W.
Purification and properties of phosphoserine aminotransferase from bovine liver
Arch. Biochem. Biophys.
254
319-328
1987
Bos taurus
Basurko, M.J.; Marche, M.; Darriet, M.; Cassaigne, A.
Catalytic properties and specificity of phosphoserine aminotransferase from beef liver
Biochem. Soc. Trans.
17
787-788
1989
Bos taurus
-
Stolz, M.; Doernemann, D.
Purification, charcterization and N-terminal sequence of phosphoserine aminotransferase from the green alga Scenedesmus obliquus, mutant C-2 A'
Z. Naturforsch. C
49c
63-69
1993
Tetradesmus obliquus
-
Tanaka, T.; Yamamoto, S.; Moriya, T.; Taniguchi, M.; Hayashi, H.; Kagamiyama, H.; Oi, S.
Aspartate aminotransferase from a thermophilic formate-utilizing methanogen, Methanobacterium thermoformicicum strain SF-4: relation to serine and phosphoserine aminotransferases, but not to the aspartate aminotransferase family
J. Biochem.
115
309-317
1994
Methanothermobacter thermautotrophicus, Methanothermobacter thermautotrophicus SF-4
Stolz, M.; Doernemann, D.
Kinetic characteristics, substrate specificity and catalytic properties of phosphoserine aminotransferase from the green alga Scenedesmus obliquus, mutant C-2A'
Z. Naturforsch. C
50c
630-637
1995
Tetradesmus obliquus
-
Battchikova, N.; Himanen, J.P.; Ahjolahti, M.; Korpela, T.
Phosphoserine aminotransferase from Bacillus circulans subsp. alkalophilus: purification, gene cloning and sequencing
Biochim. Biophys. Acta
1295
187-194
1996
Niallia circulans
Saito, K.; Takagi, Y.; Ling, H.C.; Takahashi, H.; Noji, M.
Molecular cloning, characterization and expression of cDNA encoding phosphoserine aminotransferase involved in phosphorylated pathway of serine biosynthesis from spinach
Plant Mol. Biol.
33
359-366
1997
Spinacia oleracea
Ho, C.L.; Noji, M.; Saito, M.; Yamazaki, M.; Saito, K.
Molecular characterization of plastidic phosphoserine aminotransferase in serine biosynthesis from Arabidopsis
Plant J.
16
443-452
1998
Spinacia oleracea, Arabidopsis thaliana (Q96255), Arabidopsis thaliana
Basurko, M.J.; Marche, M.; Darriet, M.; Cassaigne, A.
Phosphoserine aminotransferase, the second step-catalyzing enzyme for serine biosynthesis
IUBMB Life
48
525-529
1999
Bos taurus
Hester, G.; Stark, W.; Moser, M.; Kallen, J.; Markovic-Housley, Z.; Jansonius, J.N.
Crystal structure of phosphoserine aminotransferase from Escherichia coli at 2.3 A resolution: comparison of the unligated enzyme and a complex with alpha-methyl-l-glutamate
J. Mol. Biol.
286
829-850
1999
Escherichia coli
Baek, J.Y.; Jun do, Y.; Taub, D.; Kim, Y.H.
Characterization of human phosphoserine aminotransferase involved in the phosphorylated pathway of L-serine biosynthesis
Biochem. J.
373
191-200
2003
Homo sapiens (Q9Y617), Homo sapiens
Peters-Wendisch, P.; Stolz, M.; Etterich, H.; Kennerknecht, N.; Sahm, H.; Eggeling, L.
Metabolic engineering of Corynebacterium glutamicum for L-serine production
Appl. Environ. Microbiol.
71
7139-7144
2005
Corynebacterium glutamicum
Dubnovitsky, A.P.; Ravelli, R.B.; Popov, A.N.; Papageorgiou, A.C.
Strain relief at the active site of phosphoserine aminotransferase induced by radiation damage
Protein Sci.
14
1498-1507
2005
Alkalihalobacillus alcalophilus
Dubnovitsky, A.P.; Kapetaniou, E.G.; Papageorgiou, A.C.
Enzyme adaptation to alkaline pH: atomic resolution (1.08 A) structure of phosphoserine aminotransferase from Bacillus alcalophilus
Protein Sci.
14
97-110
2005
Alkalihalobacillus alcalophilus
Martens, J.W.; Nimmrich, I.; Koenig, T.; Look, M.P.; Harbeck, N.; Model, F.; Kluth, A.; Bolt-de Vries, J.; Sieuwerts, A.M.; Portengen, H.; Meijer-Van Gelder, M.E.; Piepenbrock, C.; Olek, A.; Hoefler, H.; Kiechle, M.; Klijn, J.G.; Schmitt, M.; Maier, S.; Foekens, J.A.
Association of DNA methylation of phosphoserine aminotransferase with response to endocrine therapy in patients with recurrent breast cancer
Cancer Res.
65
4101-4107
2005
Homo sapiens
Helgadottir, S.; Rosas-Sandoval, G.; Soell, D.; Graham, D.E.
Biosynthesis of phosphoserine in the Methanococcales
J. Bacteriol.
189
575-582
2007
Methanococcus maripaludis
Ali, V.; Nozaki, T.
Biochemical and functional characterization of phosphoserine aminotransferase from Entamoeba histolytica, which possesses both phosphorylated and non-phosphorylated serine metabolic pathways
Mol. Biochem. Parasitol.
145
71-83
2006
Arabidopsis thaliana, Entamoeba histolytica (Q60I38), Entamoeba histolytica
Kapetaniou, E.G.; Thanassoulas, A.; Dubnovitsky, A.P.; Nounesis, G.; Papageorgiou, A.C.
Effect of pH on the structure and stability of Bacillus circulans ssp. alkalophilus phosphoserine aminotransferase: thermodynamic and crystallographic studies
Proteins
63
742-753
2006
Niallia circulans (Q59196), Niallia circulans
Vie, N.; Copois, V.; Bascoul-Mollevi, C.; Denis, V.; Bec, N.; Robert, B.; Fraslon, C.; Conseiller, E.; Molina, F.; Larroque, C.; Martineau, P.; Del Rio, M.; Gongora, C.
Overexpression of phosphoserine aminotransferase PSAT1 stimulates cell growth and increases chemoresistance of colon cancer cells
Mol. Cancer
7
14
2008
Homo sapiens (Q9Y617), Homo sapiens
Coulibaly, F.; Lassalle, E.; Baker, H.M.; Baker, E.N.
Structure of phosphoserine aminotransferase from Mycobacterium tuberculosis
Acta Crystallogr. Sect. D
68
553-563
2012
Mycobacterium tuberculosis (P9WQ73), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (P9WQ73)
Mishra, V.; Kumar, A.; Ali, V.; Nozaki, T.; Zhang, K.Y.; Bhakuni, V.
Role of conserved active site tryptophan-101 in functional activity and stability of phosphoserine aminotransferase from an enteric human parasite
Amino Acids
43
483-491
2012
Entamoeba histolytica
Mishra, V.; Kumar, A.; Ali, V.; Nozaki, T.; Zhang, K.Y.; Bhakuni, V.
Novel protein-protein interactions between Entamoeba histolyticad-phosphoglycerate dehydrogenase and phosphoserine aminotransferase
Biochimie
94
1676-1686
2012
Entamoeba histolytica
Mishra, V.; Ali, V.; Nozaki, T.; Bhakuni, V.
Biophysical characterization of Entamoeba histolytica phosphoserine aminotransferase (EhPSAT): role of cofactor and domains in stability and subunit assembly
Eur. Biophys. J.
40
599-610
2011
Entamoeba histolytica
Drewke, C., Klein, M.; Clade, D.; Arenz, A.; Muller, R.; Leistner, E.
4-O-phosphoryl-L-threonine, a substrate of the pdxC(serC) gene product involved in vitamin B6 biosynthesis
FEBS Lett.
390
179-82
1996
Escherichia coli
Metcalf, W.W.; Zhang, J.K.; Shi, X.; Wolfe, R.S.
Molecular, genetic, and biochemical characterization of the serC gene of Methanosarcina barkeri Fusaro
J. Bacteriol.
178
5797-5802
1996
Methanosarcina barkeri (P52878), Methanosarcina barkeri, Methanosarcina barkeri DSM 804 (P52878)
Donini, S.; Ferrari, M.; Fedeli, C.; Faini, M.; Lamberto, I.; Marletta, A.S.; Mellini, L.; Panini, M.; Percudani, R.; Pollegioni, L.; Caldinelli, L.; Petrucco, S.; Peracchi, A.
Recombinant production of eight human cytosolic aminotransferases and assessment of their potential involvement in glyoxylate metabolism
Biochem. J.
422
265-272
2009
Homo sapiens (Q9Y617)
Battula, P.; Dubnovitsky, A.P.; Papageorgiou, A.C.
Structural basis of L-phosphoserine binding to Bacillus alcalophilus phosphoserine aminotransferase
Acta Crystallogr. Sect. D
69
804-811
2013
Alkalihalobacillus alcalophilus (Q9RME2), Alkalihalobacillus alcalophilus
Wang, Z.; Jiang, Y.; Sun, Y.; Li, Q.; Li, Y.; Du, Z.; Liu, Y.; Qin, L.
Molecular characterization of a phosphoserine aminotransferase gene in Antheraea pernyi and assessment of its value for phylogenetic inference
Biochem. Syst. Ecol.
48
293-300
2013
Antheraea pernyi (E3VVV6)
-
Singh, R.K.; Mazumder, M.; Sharma, B.; Gourinath, S.
Structural investigation and inhibitory response of halide on phosphoserine aminotransferase from Trichomonas vaginalis
Biochim. Biophys. Acta
1860
1508-1518
2016
Trichomonas vaginalis
Liu, B.; Jia, Y.; Cao, Y.; Wu, S.; Jiang, H.; Sun, X.; Ma, J.; Yin, X.; Mao, A.; Shang, M.
Overexpression of phosphoserine aminotransferase 1 (PSAT1) predicts poor prognosis and associates with tumor progression in human esophageal squamous cell carcinoma
Cell. Physiol. Biochem.
39
395-406
2016
Homo sapiens
Yu, J.; Xiao, F.; Guo, Y.; Deng, J.; Liu, B.; Zhang, Q.; Li, K.; Wang, C.; Chen, S.; Guo, F.
Hepatic phosphoserine aminotransferase 1 regulates insulin sensitivity in mice via Tribbles Homolog 3
Diabetes
64
1591-1602
2015
Homo sapiens
Klemke, F.; Baier, A.; Knoop, H.; Kern, R.; Jablonsky, J.; Beyer, G.; Volkmer, T.; Steuer, R.; Lockau, W.; Hagemann, M.
Identification of the light-independent phosphoserine pathway as an additional source of serine in the cyanobacterium Synechocystis sp. PCC 6803
Microbiology
161
1050-1060
2015
Synechocystis sp. (P74281)
Deng, Y.; Wu, D.; Tachibana, H.; Cheng, X.
Molecular cloning and expression of phosphoglycerate dehydrogenase and phosphoserine aminotransferase in the serine biosynthetic pathway from Acanthamoeba castellanii
Parasitol. Res.
114
1387-1395
2015
Acanthamoeba castellanii (V9NC98), Acanthamoeba castellanii
Haque, M.R.; Hirowatari, A.; Koyanagi, A.; Ichinose, T.; Abiru, M.; Mohri, S.; Furuya, S.; Yamamoto, K.
Molecular characterization and expression analysis of a phosphoserine aminotransferase involving L-serine synthesis from silkworm, Bombyx mori
Arch. Insect Biochem. Physiol.
101
e21553
2019
Bombyx mori (H9JSH4), Bombyx mori (Q2F5M8), Bombyx mori, Bombyx mori p50T (H9JSH4), Bombyx mori b94 (Q2F5M8)
Zhang, Y.; Ma, C.; Dischert, W.; Soucaille, P.; Zeng, A.P.
Engineering of phosphoserine aminotransferase increases the conversion of L-homoserine to 4-hydroxy-2-ketobutyrate in a glycerol-independent pathway of 1,3-propanediol production from glucose
Biotechnol. J.
14
e1900003
2019
Escherichia coli (P23721), Escherichia coli, Escherichia coli MG1655 (P23721)
Yang, C.; Stampouloglou, E.; Kingston, N.; Zhang, L.; Monti, S.; Varelas, X.
Glutamine-utilizing transaminases are a metabolic vulnerability of TAZ/YAP-activated cancer cells
EMBO Rep.
19
e43577
2018
Homo sapiens (Q9Y617), Homo sapiens
Wulfert, S.; Krueger, S.
Phosphoserine aminotransferase1 is part of the phosphorylated pathways for serine biosynthesis and essential for light and sugar-dependent growth promotion
Front. Plant Sci.
871
1712
2018
Arabidopsis thaliana (Q96255), Arabidopsis thaliana (Q9SHP0)
Sekula, B.; Ruszkowski, M.; Dauter, Z.
Structural analysis of phosphoserine aminotransferase (isoform 1) from Arabidopsis thaliana - the enzyme involved in the phosphorylated pathway of serine biosynthesis
Front. Plant Sci.
9
876
2018
Arabidopsis thaliana (Q96255), Arabidopsis thaliana
Singh, R.K.; Tomar, P.; Dharavath, S.; Kumar, S.; Gourinath, S.
N-terminal residues are crucial for quaternary structure and active site conformation for the phosphoserine aminotransferase from enteric human parasite E. histolytica
Int. J. Biol. Macromol.
132
1012-1023
2019
Entamoeba histolytica (Q60I38), Entamoeba histolytica, Entamoeba histolytica HM1:IMSS (Q60I38)
Koivulehto, M.; Battchikova, N.; Korpela, S.; Khalikova, E.; Zavialov, A.; Korpela, T.
Comparison of kinetic and enzymatic properties of intracellular phosphoserine aminotransferases from alkaliphilic and neutralophilic bacteria
Open Chem.
18
149-164
2020
Bos taurus (A0A3S5ZPF7), Escherichia coli (E2QJB8), Escherichia coli (P23721), Glycine max (I1JCA9), Niallia circulans (Q59196), Alkalihalobacillus alcalophilus (Q9RME2), Tetradesmus obliquus (Q9S8N7), Ovis aries (W5PS11)
-
De Marchi, T.; Timmermans, M.A.; Sieuwerts, A.M.; Smid, M.; Look, M.P.; Grebenchtchikov, N.; Sweep, F.C.G.J.; Smits, J.G.; Magdolen, V.; van Deurzen, C.H.M.; Foekens, J.A.; Umar, A.; Martens, J.W.
Phosphoserine aminotransferase 1 is associated to poor outcome on tamoxifen therapy in recurrent breast cancer
Sci. Rep.
7
2099
2017
Homo sapiens (Q9Y617), Homo sapiens
html completed
