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Information on EC 2.4.99.12 - lipid IVA 3-deoxy-D-manno-octulosonic acid transferase and Organism(s) Pseudomonas aeruginosa

for references in articles please use BRENDA:EC2.4.99.12
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EC Tree
IUBMB Comments
The enzyme from Escherichia coli is bifunctional and transfers two 3-deoxy-D-manno-oct-2-ulosonate residues to lipid IVA (cf. EC 2.4.99.13 [(Kdo)-lipid IVA 3-deoxy-D-manno-octulosonic acid transferase]) . The monofunctional enzymes from Bordetella pertusis, Aquifex aeolicus and Haemophilus influenzae catalyse the transfer of a single 3-deoxy-D-manno-oct-2-ulosonate residue from CMP-3-deoxy-D-manno-oct-2-ulosonate to lipid IVA [2-4]. The enzymes from Chlamydia transfer three or more 3-deoxy-D-manno-oct-2-ulosonate residues and generate genus-specific epitopes .
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Pseudomonas aeruginosa
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Word Map
The taxonomic range for the selected organisms is: Pseudomonas aeruginosa
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
Synonyms
kdo transferase, 3-deoxy-d-manno-oct-2-ulosonic acid transferase, monofunctional kdo transferase, multi-functional kdo-transferase, 3-deoxy-d-manno-octulosonic acid transferase, mono-functional kdo transferase, 3-deoxy-manno-octulosonic acid transferase, more
PATHWAY SOURCE
PATHWAYS
-
-, -, -, -, -, -, -, -
SYSTEMATIC NAME
IUBMB Comments
CMP-3-deoxy-D-manno-oct-2-ulosonate:lipid IVA 3-deoxy-D-manno-oct-2-ulosonate transferase
The enzyme from Escherichia coli is bifunctional and transfers two 3-deoxy-D-manno-oct-2-ulosonate residues to lipid IVA (cf. EC 2.4.99.13 [(Kdo)-lipid IVA 3-deoxy-D-manno-octulosonic acid transferase]) [1]. The monofunctional enzymes from Bordetella pertusis, Aquifex aeolicus and Haemophilus influenzae catalyse the transfer of a single 3-deoxy-D-manno-oct-2-ulosonate residue from CMP-3-deoxy-D-manno-oct-2-ulosonate to lipid IVA [2-4]. The enzymes from Chlamydia transfer three or more 3-deoxy-D-manno-oct-2-ulosonate residues and generate genus-specific epitopes [5].
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
A0A8G4E6M5_PSEAI
425
0
46505
TrEMBL
-
A0A659BPX5_PSEAI
425
0
46589
TrEMBL
-
A0A8G2S2C4_PSEAI
425
0
46473
TrEMBL
-
A0A8G4D5Z5_PSEAI
425
0
46503
TrEMBL
-
A0A367MD76_PSEAI
373
0
41116
TrEMBL
-
A0A8G6QMZ2_PSEAI
425
0
46513
TrEMBL
-
A0A8G2RU81_PSEAI
425
0
46455
TrEMBL
-
A0A8G3YH65_PSEAI
425
0
46515
TrEMBL
-
A0A485FXD6_PSEAI
222
0
23479
TrEMBL
-
A0A8G3KYH6_PSEAI
422
0
46217
TrEMBL
-
A0A5F1BLL6_PSEAI
425
0
46473
TrEMBL
-
A0A6H3GID4_PSEAI
425
0
46383
TrEMBL
-
A0A8G7BWC0_PSEAI
425
0
46558
TrEMBL
-
A0A8F9NQ06_PSEAI
425
0
46519
TrEMBL
-
A0A3M5DDH2_PSEAI
161
0
16979
TrEMBL
-
A0A8G6G447_PSEAI
425
0
46498
TrEMBL
-
A0A509JHP2_PSEAI
425
0
46489
TrEMBL
-
A0A8G6YPP2_PSEAI
425
0
46528
TrEMBL
-
A0A6A9JZ73_PSEAI
425
0
46466
TrEMBL
-
A0A2R3IR77_PSEAI
425
0
46219
TrEMBL
-
A0A7U0JYC1_PSEAI
425
0
46604
TrEMBL
-
A0A8G4LWJ0_PSEAI
425
0
46503
TrEMBL
-
A0A8G7HZY4_PSEAI
425
0
46459
TrEMBL
-
A0A444M7F2_PSEAI
425
0
46486
TrEMBL
-
A0A8G7RTT6_PSEAI
425
0
46514
TrEMBL
-
A0A5N3Z7F9_PSEAI
425
0
46515
TrEMBL
-
A0A8G6ZHH2_PSEAI
425
0
46455
TrEMBL
-
A0A8G2KFE2_PSEAI
425
0
46517
TrEMBL
-
A0A0D6ISR5_PSEAI
425
0
46487
TrEMBL
-
A0A3M5DEC3_PSEAI
390
0
42208
TrEMBL
-
A0A8G6LH91_PSEAI
425
0
46486
TrEMBL
-
A0A8G7IQ66_PSEAI
425
0
46545
TrEMBL
-
A0A485GQD9_PSEAI
425
0
46165
TrEMBL
-
A0A0A8RI59_PSEAI
425
0
46419
TrEMBL
-
A0A431XA14_PSEAI
425
0
46196
TrEMBL
-
A0A4U9M3S8_PSEAI
425
0
46441
TrEMBL
-
A0A8B4ZNR0_PSEAI
425
0
46529
TrEMBL
-
A0A6B0J1F6_PSEAI
425
0
46515
TrEMBL
-
A0A8F9NSE2_PSEAI
425
0
46501
TrEMBL
-
A0A8F9KIH1_PSEAI
425
0
46444
TrEMBL
-
A0A7M3B3U3_PSEAI
425
0
46561
TrEMBL
-
A0A8G7CSN4_PSEAI
425
0
46500
TrEMBL
-