Information on EC 2.3.3.9 - malate synthase

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The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea

EC NUMBER
COMMENTARY
2.3.3.9
-
RECOMMENDED NAME
GeneOntology No.
malate synthase
PATHWAY
KEGG Link
MetaCyc Link
chitin degradation to ethanol
-
glycolate and glyoxylate degradation II
-
Glyoxylate and dicarboxylate metabolism
-
glyoxylate cycle
-
L-arabinose degradation IV
-
Metabolic pathways
-
methylaspartate cycle
-
Microbial metabolism in diverse environments
-
Pyruvate metabolism
-
TCA cycle IV (2-oxoglutarate decarboxylase)
-
TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)
-
xylose degradation IV
-
SYSTEMATIC NAME
IUBMB Comments
acetyl-CoA:glyoxylate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming)
-
SYNONYMS
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
EC 4.1.3.2
-
-
formerly
-
GCE(13-573)
-
N-terminal malate synthase-active domain of glyoxylate cycle enzyme
glcB
Sinorhizobium meliloti Rm5000
-
-
-
glyoxylate cycle enzyme
-
bifunctional enzyme possessing malate synthase and isocitrate lyase activities
glyoxylate transacetase
-
-
-
-
glyoxylic transacetase
-
-
-
-
L-malate glyoxylate-lyase (CoA-acetylating)
-
-
-
-
malate synthase
-
-
malate synthase
Q5YLB8
-
malate synthase
Paracoccidioides brasiliensis Pb01
Q5YLB8
-
-
malate synthase
-
-
malate synthase 1
-
-
-
-
malate synthase A
-
-
malate synthase A
-
-
malate synthase A
D4GTL2
isoform
malate synthase G
-
-
-
-
malate synthase G
Escherichia coli C41
-
-
-
malate synthase G
D4GTL2
isoform
malate synthase G
-
-
malate synthase G
P0A5J4
-
malate synthase G
Mycobacterium tuberculosis Rv1837c
P0A5J4
-
-
malate synthase G
-
-
malate synthase H
D4GTL2
isoform
malate synthetase
-
-
-
-
malic synthetase
-
-
-
-
malic-condensing enzyme
-
-
-
-
MSA
D4GTL2
-
MSG
-
-
-
-
MSG
Escherichia coli C41
-
-
-
MSG
D4GTL2
-
MSH
D4GTL2
-
SSO1334
Q97YI7
gene name
CAS REGISTRY NUMBER
COMMENTARY
9013-48-3
-
ORGANISM
COMMENTARY
LITERATURE
SEQUENCE CODE
SEQUENCE DB
SOURCE
thermophilic
-
-
Manually annotated by BRENDA team
pathogenic isolates of Candida albicans obtained from HIV/AIDS, diabetic and burn patients
-
-
Manually annotated by BRENDA team
Candida tropicalis pK 233
pK 233
-
-
Manually annotated by BRENDA team
induced by growth on acetate and light
Swissprot
Manually annotated by BRENDA team
formerly Vibrio sp. strain ABE-1
-
-
Manually annotated by BRENDA team
cucumber
-
-
Manually annotated by BRENDA team
Cucurbita sp.
-
-
-
Manually annotated by BRENDA team
isoform G
-
-
Manually annotated by BRENDA team
Escherichia coli C41
-
-
-
Manually annotated by BRENDA team
bifunctional malate synthase/isocitrate lyase, induced by growth on ethanol
Q8LPA6
Swissprot
Manually annotated by BRENDA team
growth on glucose
-
-
Manually annotated by BRENDA team
sunflower
-
-
Manually annotated by BRENDA team
Mycobacterium tuberculosis Rv1837c
-
UniProt
Manually annotated by BRENDA team
ssp. indica cv Guangluai 4
-
-
Manually annotated by BRENDA team
Paracoccidioides brasiliensis Pb01
strain Pb01
UniProt
Manually annotated by BRENDA team
castor bean
-
-
Manually annotated by BRENDA team
stains KM10-15
-
-
Manually annotated by BRENDA team
Streptomyces clavuligerus NRRL3585
NRRL3585
SwissProt
Manually annotated by BRENDA team
expression in Escherichia coli
Q7BNB5
Swissprot
Manually annotated by BRENDA team
M130
Q7BNB5
SwissProt
Manually annotated by BRENDA team
Streptomyces coelicolor A3(2) M130
M130
Q7BNB5
SwissProt
Manually annotated by BRENDA team
expression with GST-tag in Escherichia coli
Swissprot
Manually annotated by BRENDA team
ACTIVATING COMPOUND
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
IMAGE
EDTA
-
0.01 mM, 10% activation
Triton X-100
-
activation
pI VALUE
pI VALUE MAXIMUM
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
8.45
-
Q5YLB8
calculated
PDB
SCOP
CATH
ORGANISM
Escherichia coli (strain K12)
Escherichia coli (strain K12)
Escherichia coli (strain K12)
Escherichia coli (strain K12)
Escherichia coli (strain K12)
Escherichia coli (strain K12)
Escherichia coli (strain K12)
Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2)
Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2)
Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2)
Mycobacterium leprae (strain Br4923)
POSTTRANSLATIONAL MODIFICATION
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
side-chain modification
-
enzyme synthesized as a monomeric precursor in the cytoplasm, processing which is a prerequisite for oligomerization takes place rapidly in the glyoxysomes
side-chain modification
-
enzyme contains phospholipid
no modification
-
no glycoprotein
side-chain modification
-
posttranslational phosphorylation at a Ser residue
no modification
-
contains no covalent linked carbohydrate residues
APPLICATION
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
agriculture
-
enzyme is required for pathogenicity of the fungal phytopathogen