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Information on EC 2.3.2.23 - E2 ubiquitin-conjugating enzyme and Organism(s) Bos taurus

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EC Tree
     2 Transferases
         2.3 Acyltransferases
             2.3.2 Aminoacyltransferases
                2.3.2.23 E2 ubiquitin-conjugating enzyme
IUBMB Comments
The E2 ubiquitin-conjugating enzyme acquires the activated ubquitin from the E1 ubiquitin-activating enzyme (EC 6.2.1.45) and binds it via a transthioesterification reaction to itself. In the human enzyme the catalytic center is located at Cys-87 where ubiquitin is bound via its C-terminal glycine in a thioester linkage.
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Bos taurus
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Word Map
The taxonomic range for the selected organisms is: Bos taurus
The enzyme appears in selected viruses and cellular organisms
Reaction Schemes
S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine
+
[E2 ubiquitin-conjugating enzyme]-L-cysteine
=
[E1 ubiquitin-activating enzyme]-L-cysteine
+
S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine
Synonyms
ube2c, cdc34, ubc13, ube2t, ubch10, e2 enzyme, ube2s, ubch7, e2 ubiquitin-conjugating enzyme, ube2l3, more
PATHWAY SOURCE
PATHWAYS
-
-
SYSTEMATIC NAME
IUBMB Comments
S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine:[E2 ubiquitin-conjugating enzyme] ubiquitinyl transferase
The E2 ubiquitin-conjugating enzyme acquires the activated ubquitin from the E1 ubiquitin-activating enzyme (EC 6.2.1.45) and binds it via a transthioesterification reaction to itself. In the human enzyme the catalytic center is located at Cys-87 where ubiquitin is bound via its C-terminal glycine in a thioester linkage.
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
UB2E3_BOVIN
207
0
22913
Swiss-Prot
other Location (Reliability: 2)
UB2G2_BOVIN
165
0
18552
Swiss-Prot
other Location (Reliability: 2)
UBE2S_BOVIN
223
0
23896
Swiss-Prot
other Location (Reliability: 2)
UBE2T_BOVIN
195
0
21765
Swiss-Prot
other Location (Reliability: 5)
UBE2W_BOVIN
151
0
17331
Swiss-Prot
other Location (Reliability: 2)
UBE2H_BOVIN
183
0
20655
Swiss-Prot
other Location (Reliability: 3)
UBE2K_BOVIN
200
0
22407
Swiss-Prot
other Location (Reliability: 2)
UBE2N_BOVIN
152
0
17138
Swiss-Prot
other Location (Reliability: 4)
UB2J2_BOVIN
259
1
28848
Swiss-Prot
other Location (Reliability: 5)
UB2L3_BOVIN
154
0
17862
Swiss-Prot
other Location (Reliability: 2)
UB2L6_BOVIN
153
0
17825
Swiss-Prot
other Location (Reliability: 1)
UB2Q2_BOVIN
342
0
38717
Swiss-Prot
other Location (Reliability: 2)
UBE2B_BOVIN
152
0
17312
Swiss-Prot
other Location (Reliability: 5)
UBE2C_BOVIN
179
0
19608
Swiss-Prot
other Location (Reliability: 4)
UB2D1_BOVIN
147
0
16602
Swiss-Prot
other Location (Reliability: 3)
UB2D2_BOVIN
147
0
16735
Swiss-Prot
other Location (Reliability: 2)
UB2D3_BOVIN
147
0
16745
Swiss-Prot
other Location (Reliability: 2)