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Information on EC 2.3.1.48 - histone acetyltransferase and Organism(s) Sus scrofa

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EC Tree
     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.48 histone acetyltransferase
IUBMB Comments
A group of enzymes acetylating histones. Several of the enzymes can also acetylate lysines in other proteins [3,4].
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Select one or more organisms in this record: ?
This record set is specific for:
Sus scrofa
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Word Map
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The taxonomic range for the selected organisms is: Sus scrofa
The enzyme appears in selected viruses and cellular organisms
Synonyms
clock, histone acetyltransferase, n-acetyltransferase, tip60, histone acetyltransferases, cbp/p300, creb-binding protein, ep300, crebbp, creb binding protein, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
acetyltransferase, histone
-
-
-
-
histone acetokinase
-
-
-
-
histone acetylase
-
-
-
-
histone transacetylase
-
-
-
-
nucleosome-histone acetyltransferase
-
-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Acyl group transfer
-
-
-
-
SYSTEMATIC NAME
IUBMB Comments
acetyl-CoA:[protein]-L-lysine acetyltransferase
A group of enzymes acetylating histones. Several of the enzymes can also acetylate lysines in other proteins [3,4].
CAS REGISTRY NUMBER
COMMENTARY hide
9054-51-7
-
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
acetyl-CoA + histone
CoA + acetylhistone
show the reaction diagram
acetyl-CoA + histone H3
CoA + acetylhistone H3
show the reaction diagram
-
histone H3: preferred substrate
-
-
?
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
iodoacetamide
-
-
K+
-
175 mM: 50% inhibition
Mg2+
-
37 mM: 50% inhibition
N-ethylmaleimide
-
-
Na+
-
160 mM: 50% inhibition
KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
additional information
additional information
-
-
-
TURNOVER NUMBER [1/s]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.8 - 12
acetyl-CoA
0.8 - 12
histone
Ki VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
175
K+
-
-
pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
7.4
-
assay at
7.5
-
-
pH RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
6.6 - 8.4
-
about 50% of activity maximum at pH 6.6 and pH 8.4
TEMPERATURE OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
37
-
assay at
4 - 37
-
-
TEMPERATURE RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
4 - 47
-
4-37°C: activity maximum, 47°C: 50% of activity maximum
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
NCOA1_PIG
1440
0
156925
Swiss-Prot
other Location (Reliability: 2)
A0A480XCG4_PIG
413
0
48793
TrEMBL
other Location (Reliability: 2)
A0A4X1U7I2_PIG
316
0
34833
TrEMBL
other Location (Reliability: 3)
A0A8D0TKX4_PIG
1641
0
183748
TrEMBL
other Location (Reliability: 2)
F1S0Q0_PIG
857
0
96311
TrEMBL
other Location (Reliability: 5)
A0A8D0PFQ4_PIG
2315
0
251717
TrEMBL
other Location (Reliability: 3)
A0A8D1Y424_PIG
2358
0
256488
TrEMBL
other Location (Reliability: 2)
A0A4X1U4T4_PIG
1996
0
222610
TrEMBL
other Location (Reliability: 2)
A0A8D0RQ96_PIG
857
0
96283
TrEMBL
other Location (Reliability: 5)
A0A480SKM4_PIG
419
0
49327
TrEMBL
other Location (Reliability: 1)
A0A480JFU2_PIG
1259
0
142768
TrEMBL
other Location (Reliability: 2)
A0A4X1UNP1_PIG
580
0
66874
TrEMBL
other Location (Reliability: 3)
A0A8D1E8N3_PIG
2427
0
262820
TrEMBL
other Location (Reliability: 2)
A0A8D0Z968_PIG
1773
0
198747
TrEMBL
other Location (Reliability: 2)
A0A8D0ZGC2_PIG
1644
0
184163
TrEMBL
other Location (Reliability: 2)
A0A8D1X774_PIG
2065
0
230377
TrEMBL
other Location (Reliability: 2)
A0A8D0JXR4_PIG
380
0
44492
TrEMBL
other Location (Reliability: 1)
A0A4X1VNG8_PIG
242
0
27408
TrEMBL
other Location (Reliability: 2)
A0A8D0S0V8_PIG
337
0
37078
TrEMBL
other Location (Reliability: 2)
A0A480VCN1_PIG
838
0
94004
TrEMBL
other Location (Reliability: 5)
A0A8D1HMJ0_PIG
2062
0
229990
TrEMBL
other Location (Reliability: 2)
A0A8D0VKX5_PIG
2440
0
264389
TrEMBL
other Location (Reliability: 2)
A0A5G2QX77_PIG
546
0
61786
TrEMBL
other Location (Reliability: 3)
A0A8D0V2M9_PIG
576
0
64855
TrEMBL
other Location (Reliability: 3)
A0A5G2QWM2_PIG
579
0
66699
TrEMBL
other Location (Reliability: 1)
A0A8D1YXY9_PIG
783
0
87282
TrEMBL
other Location (Reliability: 1)
F1RIR8_PIG
458
0
52431
TrEMBL
other Location (Reliability: 4)
A0A8D1MLB8_PIG
156
0
17146
TrEMBL
other Location (Reliability: 2)
A0A8D1HNE8_PIG
832
0
93034
TrEMBL
other Location (Reliability: 1)
A0A8D0VBW0_PIG
2421
0
264028
TrEMBL
other Location (Reliability: 2)
A0A8D2BVV5_PIG
2427
0
262791
TrEMBL
other Location (Reliability: 2)
A0A8D1T3L7_PIG
612
0
70751
TrEMBL
other Location (Reliability: 2)
A0A8D0P938_PIG
2303
0
250199
TrEMBL
other Location (Reliability: 3)
A0A8D0J0Q5_PIG
837
0
95731
TrEMBL
Secretory Pathway (Reliability: 5)
A0A5G2QCV0_PIG
472
0
55135
TrEMBL
other Location (Reliability: 3)
A0A8D1M1R7_PIG
2011
0
224037
TrEMBL
other Location (Reliability: 2)
A0A8D0PB78_PIG
2441
0
264666
TrEMBL
other Location (Reliability: 3)
A0A8D0PBL5_PIG
2267
0
246790
TrEMBL
other Location (Reliability: 3)
A0A4X1U6S0_PIG
857
0
96311
TrEMBL
other Location (Reliability: 5)
A0A8D1CU92_PIG
2440
0
264388
TrEMBL
other Location (Reliability: 2)
A0A8D1HFL3_PIG
1770
0
198332
TrEMBL
other Location (Reliability: 2)
A0A8D0NEM4_PIG
893
0
99612
TrEMBL
other Location (Reliability: 5)
A0A480QJT4_PIG
2421
0
264028
TrEMBL
other Location (Reliability: 2)
A0A8D1FZL3_PIG
428
0
48893
TrEMBL
other Location (Reliability: 4)
A0A8D0U7T8_PIG
513
0
58598
TrEMBL
other Location (Reliability: 1)
A0A480MKR8_PIG
1268
0
140810
TrEMBL
Secretory Pathway (Reliability: 2)
A0A8D1LZG4_PIG
1710
0
191568
TrEMBL
other Location (Reliability: 2)
A0A8D0U7L9_PIG
2405
0
260574
TrEMBL
Secretory Pathway (Reliability: 4)
A0A8D1L0U5_PIG
2264
0
246883
TrEMBL
other Location (Reliability: 4)
A0A8D1RE75_PIG
2505
0
271123
TrEMBL
other Location (Reliability: 5)
A0A4X1VTD7_PIG
2439
0
264287
TrEMBL
other Location (Reliability: 2)
A0A4X1SNV4_PIG
2059
0
229635
TrEMBL
other Location (Reliability: 2)
A0A4X1SQ69_PIG
1877
0
209749
TrEMBL
other Location (Reliability: 2)
A0A8D1ENC1_PIG
472
0
55135
TrEMBL
other Location (Reliability: 3)
F1RK46_PIG
2440
0
264388
TrEMBL
other Location (Reliability: 2)
A0A8D0ZCY9_PIG
414
0
48743
TrEMBL
other Location (Reliability: 1)
A0A480HG38_PIG
458
0
52445
TrEMBL
other Location (Reliability: 4)
A0A480XRP2_PIG
2440
0
264416
TrEMBL
other Location (Reliability: 2)
A0A480V8Q5_PIG
967
0
111110
TrEMBL
other Location (Reliability: 2)
A0A8D1E7Z9_PIG
2426
0
262980
TrEMBL
other Location (Reliability: 2)
A0A8D1REW8_PIG
2532
0
274192
TrEMBL
other Location (Reliability: 5)
A0A4X1UNN0_PIG
610
0
70569
TrEMBL
other Location (Reliability: 3)
F1RTB9_PIG
501
0
58150
TrEMBL
other Location (Reliability: 3)
A0A8D0ND80_PIG
837
0
93925
TrEMBL
other Location (Reliability: 5)
A0A8D0LLV9_PIG
439
0
51180
TrEMBL
other Location (Reliability: 4)
F1S084_PIG
418
0
49198
TrEMBL
other Location (Reliability: 1)
A0A8D0UQN1_PIG
790
0
88906
TrEMBL
other Location (Reliability: 1)
A0A8D1LLA8_PIG
568
0
63659
TrEMBL
other Location (Reliability: 3)
D3K5K8_PIG
611
0
70626
TrEMBL
other Location (Reliability: 3)
A0A4X1ULG1_PIG
494
0
56280
TrEMBL
other Location (Reliability: 3)
A0A8D0TND3_PIG
1707
0
191199
TrEMBL
other Location (Reliability: 2)
A0A286ZID3_PIG
1710
0
191587
TrEMBL
other Location (Reliability: 2)
A0A8D1K9E2_PIG
2378
0
258053
TrEMBL
other Location (Reliability: 2)
A0A8D1E8Y4_PIG
2403
0
260173
TrEMBL
other Location (Reliability: 2)
A0A8D1Q5D4_PIG
1984
0
221262
TrEMBL
other Location (Reliability: 2)
A0A8D1AMP2_PIG
775
0
86061
TrEMBL
other Location (Reliability: 1)
A0A4X1UQK2_PIG
471
0
55048
TrEMBL
other Location (Reliability: 3)
A0A4X1V891_PIG
419
0
49327
TrEMBL
other Location (Reliability: 1)
A0A8D1PVS5_PIG
832
0
95338
TrEMBL
Secretory Pathway (Reliability: 5)
A0A8D0VK81_PIG
2301
0
250651
TrEMBL
other Location (Reliability: 2)
A0A287BIK4_PIG
461
0
53093
TrEMBL
other Location (Reliability: 1)
A0A8D1X1F3_PIG
2403
0
260144
TrEMBL
other Location (Reliability: 2)
A0A8D1BVW9_PIG
1644
0
184135
TrEMBL
other Location (Reliability: 2)
A0A8D1MYQ1_PIG
315
0
34756
TrEMBL
other Location (Reliability: 2)
A0A8D1ST71_PIG
1773
0
198719
TrEMBL
other Location (Reliability: 2)
A0A8D1U9N0_PIG
2426
0
262677
TrEMBL
other Location (Reliability: 2)
A0A8D0NAH0_PIG
2010
0
224425
TrEMBL
other Location (Reliability: 2)
A0A8D0TSN3_PIG
546
0
61816
TrEMBL
other Location (Reliability: 3)
A0A8D1M1F5_PIG
2065
0
230358
TrEMBL
other Location (Reliability: 2)
A0A8D0TSH2_PIG
1983
0
221374
TrEMBL
other Location (Reliability: 2)
A0A4X1W472_PIG
2110
0
231378
TrEMBL
Secretory Pathway (Reliability: 2)
A0A5K1U7N7_PIG
242
0
27408
TrEMBL
other Location (Reliability: 2)
A0A8D0PK75_PIG
611
0
70656
TrEMBL
other Location (Reliability: 3)
A0A287AIC0_PIG
327
0
36339
TrEMBL
Mitochondrion (Reliability: 5)
A0A4X1UTM8_PIG
500
0
58063
TrEMBL
other Location (Reliability: 3)
A0A8D1RR81_PIG
2469
0
267714
TrEMBL
other Location (Reliability: 5)
A0A8D0N8N7_PIG
1861
0
208699
TrEMBL
other Location (Reliability: 2)
A0A480QUL5_PIG
1997
0
222558
TrEMBL
other Location (Reliability: 2)
A0A8D0RU90_PIG
768
0
85371
TrEMBL
other Location (Reliability: 1)
A0A8D0Z9Q7_PIG
1710
0
191615
TrEMBL
other Location (Reliability: 2)
A0A8D0VL01_PIG
2402
0
260031
TrEMBL
other Location (Reliability: 2)
F2Z5J6_PIG
337
0
37078
TrEMBL
other Location (Reliability: 2)
A0A4X1VSS5_PIG
2401
0
259929
TrEMBL
other Location (Reliability: 2)
A0A5G2Q874_PIG
461
0
52320
TrEMBL
other Location (Reliability: 4)
A0A4X1U7I7_PIG
316
0
34829
TrEMBL
other Location (Reliability: 2)
A0A8D1UH39_PIG
2011
0
224056
TrEMBL
other Location (Reliability: 2)
A0A8D0ZA13_PIG
581
0
66961
TrEMBL
other Location (Reliability: 3)
A0A4X1VSP0_PIG
327
0
36339
TrEMBL
Mitochondrion (Reliability: 5)
A0A8D1BFJ1_PIG
775
0
86047
TrEMBL
other Location (Reliability: 1)
A0A8D0HRC4_PIG
244
0
26561
TrEMBL
other Location (Reliability: 5)
A0A287ASY2_PIG
800
0
89429
TrEMBL
other Location (Reliability: 5)
A0A8D1RNG3_PIG
2517
0
272642
TrEMBL
other Location (Reliability: 5)
A0A5G2R1Z7_PIG
613
0
70771
TrEMBL
other Location (Reliability: 2)
A0A8D1E759_PIG
298
0
34980
TrEMBL
other Location (Reliability: 1)
A0A4X1UGT9_PIG
513
0
58628
TrEMBL
other Location (Reliability: 1)
A0A8D1LZE1_PIG
1773
0
198700
TrEMBL
other Location (Reliability: 2)
A0A287BKT2_PIG
829
0
94545
TrEMBL
other Location (Reliability: 2)
A0A8D1DTJ1_PIG
2184
0
237924
TrEMBL
other Location (Reliability: 2)
A0A8D0J0T2_PIG
747
0
86570
TrEMBL
other Location (Reliability: 2)
A0A4X1V862_PIG
384
0
44764
TrEMBL
other Location (Reliability: 1)
A0A8D1YFF6_PIG
2402
0
260030
TrEMBL
other Location (Reliability: 2)
A0A480V2P3_PIG
837
0
93933
TrEMBL
other Location (Reliability: 5)
A0A4X1TIU6_PIG
458
0
52431
TrEMBL
other Location (Reliability: 4)
A0A8D0SF97_PIG
829
0
94545
TrEMBL
other Location (Reliability: 2)
A0A8D1ETP0_PIG
1990
0
221874
TrEMBL
other Location (Reliability: 2)
I3L5W7_PIG
254
0
28724
TrEMBL
Secretory Pathway (Reliability: 4)
A0A8D1TBU1_PIG
1644
0
184116
TrEMBL
other Location (Reliability: 2)
A0A8D1EBR1_PIG
2302
0
250793
TrEMBL
other Location (Reliability: 2)
A0A5G2QKQ9_PIG
315
0
34756
TrEMBL
other Location (Reliability: 2)
M3VK28_PIG
581
0
66961
TrEMBL
other Location (Reliability: 3)
A0A8D0X009_PIG
1710
0
191587
TrEMBL
other Location (Reliability: 2)
A0A8D0Z9N4_PIG
2011
0
224084
TrEMBL
other Location (Reliability: 2)
A0A4X1W1C9_PIG
2386
0
260842
TrEMBL
Secretory Pathway (Reliability: 5)
A0A287BJ10_PIG
2377
0
257910
TrEMBL
other Location (Reliability: 2)
A0A8D0NCR5_PIG
823
0
92398
TrEMBL
other Location (Reliability: 5)
A0A5G2R581_PIG
576
0
64825
TrEMBL
other Location (Reliability: 3)
A0A480XKQ4_PIG
611
0
70656
TrEMBL
other Location (Reliability: 3)
A0A8D1BTD8_PIG
1998
0
222714
TrEMBL
other Location (Reliability: 2)
A0A4X1U775_PIG
815
0
93089
TrEMBL
other Location (Reliability: 2)
A0A8D0XYW8_PIG
458
0
52445
TrEMBL
other Location (Reliability: 4)
A0A8D1LCI7_PIG
783
0
89604
TrEMBL
Secretory Pathway (Reliability: 5)
A0A8D0VLJ5_PIG
2377
0
257911
TrEMBL
other Location (Reliability: 2)
A0A8D0VL41_PIG
2426
0
262678
TrEMBL
other Location (Reliability: 2)
A0A8D0RUE9_PIG
832
0
93066
TrEMBL
other Location (Reliability: 1)
A0A8D0VK46_PIG
2425
0
262838
TrEMBL
other Location (Reliability: 2)
A0A8D1P2A7_PIG
442
0
50216
TrEMBL
other Location (Reliability: 4)
A0A8D0U7P5_PIG
2403
0
260308
TrEMBL
other Location (Reliability: 3)
A0A5G2QQJ6_PIG
156
0
17146
TrEMBL
other Location (Reliability: 2)
A0A4X1UNH3_PIG
832
0
93052
TrEMBL
other Location (Reliability: 1)
A0A480KLF9_PIG
494
0
56280
TrEMBL
other Location (Reliability: 3)
A0A8D1L191_PIG
254
0
28777
TrEMBL
Secretory Pathway (Reliability: 5)
A0A8D1E7S9_PIG
2441
0
264531
TrEMBL
other Location (Reliability: 2)
A0A5G2R328_PIG
2426
0
262677
TrEMBL
other Location (Reliability: 2)
A0A4X1ULW4_PIG
790
0
88892
TrEMBL
other Location (Reliability: 1)
A0A4X1W2B8_PIG
2141
0
234592
TrEMBL
Secretory Pathway (Reliability: 2)
A0A8D1ZFT1_PIG
1998
0
222772
TrEMBL
other Location (Reliability: 2)
A0A8D0LE48_PIG
1819
0
198263
TrEMBL
other Location (Reliability: 1)
A0A481CHC0_PIG
222
0
25309
TrEMBL
other Location (Reliability: 4)
A0A8D1QI20_PIG
315
0
34659
TrEMBL
other Location (Reliability: 2)
A0A8D1PDN7_PIG
476
0
55384
TrEMBL
other Location (Reliability: 1)
A0A8D0TM77_PIG
461
0
53093
TrEMBL
other Location (Reliability: 1)
A0A4X1VA56_PIG
413
0
48793
TrEMBL
other Location (Reliability: 2)
A0A8D1RBG0_PIG
613
0
70771
TrEMBL
other Location (Reliability: 2)
A0A8D0Z944_PIG
2065
0
230405
TrEMBL
other Location (Reliability: 2)
A0A8D0J0W9_PIG
757
0
86728
TrEMBL
other Location (Reliability: 5)
F1S2G4_PIG
2065
0
230377
TrEMBL
other Location (Reliability: 2)
A0A8D0PB63_PIG
2271
0
247313
TrEMBL
other Location (Reliability: 3)
K7GSJ7_PIG
2413
0
261319
TrEMBL
other Location (Reliability: 2)
A0A8D1SN02_PIG
1998
0
222758
TrEMBL
other Location (Reliability: 2)
A0A286ZKW1_PIG
2011
0
224056
TrEMBL
other Location (Reliability: 2)
A0A4X1SNL7_PIG
1714
0
191752
TrEMBL
other Location (Reliability: 2)
A0A8D1ID77_PIG
579
0
66699
TrEMBL
other Location (Reliability: 1)
A0A8D1T4G6_PIG
327
0
38642
TrEMBL
other Location (Reliability: 1)
A0A8D1NF04_PIG
501
0
58150
TrEMBL
other Location (Reliability: 3)
A0A8D1X2E5_PIG
2441
0
264502
TrEMBL
other Location (Reliability: 2)
A0A480QN16_PIG
2337
0
253209
TrEMBL
other Location (Reliability: 2)
A0A4X1U7J1_PIG
285
0
31466
TrEMBL
other Location (Reliability: 2)
I3L9U8_PIG
2420
0
263899
TrEMBL
other Location (Reliability: 2)
A0A8D0RUG8_PIG
795
0
88611
TrEMBL
other Location (Reliability: 1)
A0A287AGG6_PIG
1773
0
198719
TrEMBL
other Location (Reliability: 2)
A0A8D1DTJ4_PIG
838
0
94004
TrEMBL
other Location (Reliability: 5)
A0A8D1AYK7_PIG
1987
0
221579
TrEMBL
other Location (Reliability: 2)
A0A8D1U9I8_PIG
2393
0
260454
TrEMBL
other Location (Reliability: 5)
A0A8D0IZ05_PIG
755
0
87001
TrEMBL
other Location (Reliability: 1)
A0A5G2Q785_PIG
315
0
34659
TrEMBL
other Location (Reliability: 2)
A0A8D1BZW7_PIG
2413
0
261320
TrEMBL
other Location (Reliability: 2)
A0A4X1SNS7_PIG
1705
0
190941
TrEMBL
other Location (Reliability: 2)
A0A480N5P8_PIG
597
0
70013
TrEMBL
other Location (Reliability: 1)
A0A8D2C7H7_PIG
576
0
64825
TrEMBL
other Location (Reliability: 3)
A0A8D1SJP4_PIG
829
0
94559
TrEMBL
other Location (Reliability: 2)
A0A5G2QYN9_PIG
414
0
48729
TrEMBL
other Location (Reliability: 1)
A0A8D1EAS2_PIG
2414
0
261462
TrEMBL
other Location (Reliability: 2)
A0A287AQQ6_PIG
2402
0
260030
TrEMBL
other Location (Reliability: 2)
I3LRW1_PIG
831
0
92894
TrEMBL
other Location (Reliability: 1)
A0A8D0MIQ2_PIG
179
0
18960
TrEMBL
other Location (Reliability: 2)
A0A287AL22_PIG
316
0
34833
TrEMBL
other Location (Reliability: 3)
A0A8D1YRA6_PIG
546
0
61786
TrEMBL
other Location (Reliability: 3)
A0A8D1R944_PIG
244
0
26533
TrEMBL
other Location (Reliability: 5)
A0A8D0ZZY2_PIG
254
0
28724
TrEMBL
Secretory Pathway (Reliability: 4)
A0A8D0HU64_PIG
2396
0
261250
TrEMBL
other Location (Reliability: 2)
A0A287AU76_PIG
2425
0
262837
TrEMBL
other Location (Reliability: 2)
A0A8D0SN59_PIG
1997
0
222678
TrEMBL
other Location (Reliability: 2)
A0A8D1ZJ24_PIG
829
0
94603
TrEMBL
other Location (Reliability: 2)
A0A8D0V2W5_PIG
2008
0
223668
TrEMBL
other Location (Reliability: 2)
A0A8D1SSF3_PIG
857
0
96314
TrEMBL
other Location (Reliability: 5)
A0A480QT46_PIG
1882
0
210395
TrEMBL
other Location (Reliability: 2)
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
110000
-
enzyme forms I and II, gel filtration
40000
-
1 * 50000 + 1 * 40000, enzyme form II, SDS-PAGE
45000
-
1 * 45000 + 1 * 62000, enzyme form I, SDS-PAGE
50000
-
1 * 50000 + 1 * 40000, enzyme form II, SDS-PAGE
62000
-
1 * 45000 + 1 * 62000, enzyme form I, SDS-PAGE
94000
-
gel filtration, glycerol gradient ultracentrifugation
additional information
-
amino acid composition and of enzyme forms I and II are indistinguishable, specific antibodies are not cross-reactive
SUBUNIT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
dimer
TEMPERATURE STABILITY
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
37
-
glycerol protects against thermal denaturation at 37°C
GENERAL STABILITY
ORGANISM
UNIPROT
LITERATURE
glycerol protects against thermal denaturation at 37°C
-
PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
enzyme forms I and II
-
partial
-
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Attisano, L.; Lewis, P.N.
Purification and characterization of two porcine liver nuclear histone acetyltransferases
J. Biol. Chem.
265
3949-3955
1990
Sus scrofa
Manually annotated by BRENDA team
Kelner, D.N.; McCarty, K.S.
Porcine liver nuclear histone acetyltransferase. Partial purification and basic properties
J. Biol. Chem.
259
3413-3419
1984
Sus scrofa
Manually annotated by BRENDA team