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Information on EC 2.3.1.38 - [acyl-carrier-protein] S-acetyltransferase and Organism(s) Homo sapiens

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EC Tree
IUBMB Comments
This enzyme, along with EC 2.3.1.39, [acyl-carrier-protein] S-malonyltransferase, is essential for the initiation of fatty-acid biosynthesis in bacteria. The substrate acetyl-CoA protects the enzyme against inhibition by N-ethylmaleimide or iodoacetamide . This is one of the activities associated with beta-ketoacyl-[acyl-carrier-protein] synthase III (EC 2.3.1.180) .
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This record set is specific for:
Homo sapiens
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Word Map
The taxonomic range for the selected organisms is: Homo sapiens
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Synonyms
acetyl-coa:acp transacylase, acetyl-coa-acp-transacylase, acyl-coa:acp transacylase, malonyl-coa/acetyl-coa:acyl carrier protein s-acyltransferase, acetyl-coa:acyl carrier protein transacylase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
acetyl coenzyme A-acyl-carrier-protein transacylase
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acetyltransferase, [acyl-carrier-protein]
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[ACP] acetyltransferase
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[acyl-carrier-protein]acetyltransferase
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Acyl group transfer
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PATHWAY SOURCE
PATHWAYS
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SYSTEMATIC NAME
IUBMB Comments
acetyl-CoA:[acyl-carrier protein] S-acetyltransferase
This enzyme, along with EC 2.3.1.39, [acyl-carrier-protein] S-malonyltransferase, is essential for the initiation of fatty-acid biosynthesis in bacteria. The substrate acetyl-CoA protects the enzyme against inhibition by N-ethylmaleimide or iodoacetamide [4]. This is one of the activities associated with beta-ketoacyl-[acyl-carrier-protein] synthase III (EC 2.3.1.180) [5].
CAS REGISTRY NUMBER
COMMENTARY hide
37257-16-2
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UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
FAS_HUMAN
2511
0
273427
Swiss-Prot
other Location (Reliability: 2)
A0A0U1RQF0_HUMAN
2509
0
273198
TrEMBL
other Location (Reliability: 2)