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Information on EC 2.3.1.177 - 3,5-dihydroxybiphenyl synthase

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EC Tree
IUBMB Comments
A polyketide synthase that is involved in the production of the phytoalexin aucuparin. 2-Hydroxybenzoyl-CoA can also act as substrate but it leads to the derailment product 4-hydroxycoumarin (cf. EC 2.3.1.208, 4-hydroxycoumarin synthase) . This enzyme uses the same starter substrate as EC 2.3.1.151, benzophenone synthase.
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Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
biphenyl synthase, pcbis2, pcbis1, mdbis1, mdbis3, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
3 malonyl-CoA + benzoyl-CoA = 4 CoA + 3,5-dihydroxybiphenyl + 4 CO2
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PATHWAY SOURCE
PATHWAYS
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