Reference on EC 2.2.1.5 - 2-hydroxy-3-oxoadipate synthase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Hirabayashi, T.; Harada, T.
Inhibition of the alpha-ketoglutarate dehydrogenase complex from baker's yeast by acetaldehyde and glyoxylate
Agric. Biol. Chem.
36
1249-1251
1972
Saccharomyces cerevisiae
-
O'Fallon, J.V.; Brosemer, R.W.
Cellular localization of alpha-ketoglutarate: glyoxylate carboligase in rat tissues
Biochim. Biophys. Acta
499
321-328
1977
BRENDA: Oryctolagus cuniculus, Rattus norvegicus
Textmining: Rattus, Homo sapiens
Zaror-Behrens, G.; Mavrides, C.
Further studies on 2-oxoglutarate:glyoxylate carboligase activity in Tetrahymena pyriformis
Int. J. Biochem.
7
111-116
1976
Tetrahymena pyriformis
-
Zaror-Behrens, G.; Mavrides, C.
Demonstration of 2-oxoglutarate:glyoxylate carboligase activity in Tetrahymena pyriformis
Can. J. Biochem.
51
1505-1508
1973
Tetrahymena pyriformis
Yamasaki, H.; Moriyama, T.
Purification, general properties and two other catalytic activities of alpha-ketoglutarate:glyoxylate carboligase of Mycobacterium phlei
Biochim. Biophys. Acta
242
637-647
1971
Mycolicibacterium phlei
Schlossberg, M.A.; Bloom, R.J.; Richert, D.A.; Westerfeld, W.W.
Carboligase activity of alpha-ketoglutarate dehydrogenase
Biochemistry
9
1148-1153
1970
Bos taurus, Rattus norvegicus
Schlossberg, M.A.; Richert, D.A.; Bloom, R.J.; Westerfeld, W.W.
Isolation and identification of 5-hydroxy-4-ketovaleric acid as a product of alpha-ketoglutarate:glyoxylate carboligase
Biochemistry
7
333-337
1968
Bos taurus
Steward, P.R.; Quale, J.R.
The synergistic decarboxylation of glyoxylate and 2-oxoglutarate by an enzyme system from pig-liver mitochondria
Biochem. J.
102
885-897
1967
Sus scrofa
Rattan, V.; Thind, S.K.; Jethi, R.J.; Sidhu, H.; Nath, R.
Oxalate metabolism in magnesium-deficient rats
Magnes. Res.
6
127-133
1993
BRENDA: Rattus norvegicus
Textmining: Metazoa
Yamasaki, H.; Mariyama, T.
alpha-Ketoglutarate:glyoxylate carboligase activity in Escherichia coli
Biochem. Biophys. Res. Commun.
39
790-795
1970
Escherichia coli
Sidhu, H.; Gupta, R.; Thind, S.K.; Nath, R.
Oxalate metabolism in thiamine-deficient rats
Ann. Nutr. Metab.
31
354-361
1987
Rattus norvegicus
Prather, C.W.; Sisler, E.C.
Glycine and glyoxylate decarboxylation in Nicotiana rustica roots
Phytochemistry
11
1637-1647
1972
Nicotiana rustica
-
Bats, R.; Rofe, A.M.; Conyers, R.A.J.
Investigations into the effect of glyoxylate decarboxylation and transamination on oxalate formation in rat
Nephron
57
460-469
1991
Rattus norvegicus
Sergienko, E.A.; Jordan, F.
Catalytic acid-base groups in yeast pyruvate decarboxylase. 2. Insights into the specific roles of D28 and E477 from the rates and stereospecificity of formation of carboligase side products
Biochemistry
40
7369-7381
2001
Saccharomyces cerevisiae
Dills, W.L., Jr.; Chen, P.; Baillargeon, B.M.; Westgate, C.L.
High pressure liquid chromatographic study of the glyoxalate:2-ketoglutarate carboligase reaction
Biochem. Arch.
15
279-284
1999
Bos taurus
-
Nemeria, N.S.; Korotchkina, L.G.; Chakraborty, S.; Patel, M.S.; Jordan, F.
Acetylphosphinate is the most potent mechanism-based substrate-like inhibitor of both the human and Escherichia coli pyruvate dehydrogenase components of the pyruvate dehydrogenase complex
Bioorg. Chem.
34
362-379
2006
Homo sapiens
Knoll, M.; Mueller, M.; Pleiss, J.; Pohl, M.
Factors mediating activity, selectivity, and substrate specificity for the thiamin diphosphate-dependent enzymes benzaldehyde lyase and benzoylformate decarboxylase
Chembiochem
7
1928-1934
2006
Pseudomonas fluorescens, Pseudomonas putida, Pseudomonas putida (P20906)
Lingen, B.; Grotzinger, J.; Kolter, D.; Kula, M.R.; Pohl, M.
Improving the carboligase activity of benzoylformate decarboxylase from Pseudomonas putida by a combination of directed evolution and site-directed mutagenesis
Protein Eng.
15
585-593
2002
Pseudomonas putida
de Carvalho, L.P.; Zhao, H.; Dickinson, C.E.; Arango, N.M.; Lima, C.D.; Fischer, S.M.; Ouerfelli, O.; Nathan, C.; Rhee, K.Y.
Activity-based metabolomic profiling of enzymatic function: identification of Rv1248c as a mycobacterial 2-hydroxy-3-oxoadipate synthase
Chem. Biol.
17
323-332
2010
Mycobacterium tuberculosis (P9WIS5), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (P9WIS5)
Zhao, H.; de Carvalho, L.P.; Nathan, C.; Ouerfelli, O.
A protecting group-free synthesis of deazathiamine: a step toward inhibitor design
Bioorg. Med. Chem. Lett.
20
6472-6474
2010
Mycobacterium tuberculosis
Wagner, T.; Bellinzoni, M.; Wehenkel, A.; OHare, H.M.; Alzari, P.M.
Functional plasticity and allosteric regulation of alpha-ketoglutarate decarboxylase in central mycobacterial metabolism
Chem. Biol.
18
1011-1020
2011
Mycobacterium tuberculosis
Balakrishnan, A.; Jordan, F.; Nathan, C.F.
Influence of allosteric regulators on individual steps in the reaction catalyzed by Mycobacterium tuberculosis 2-hydroxy-3-oxoadipate synthase
J. Biol. Chem.
288
21688-21702
2013
Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv
Patel, H.; Shim, D.; Farinas, E.; Jordan, F.
Investigation of the donor and acceptor range for chiral carboligation catalyzed by the E1 component of the 2-oxoglutarate dehydrogenase complex
J. Mol. Catal. B
98
42-45
2013
Escherichia coli (P0AFG3)
-
Maksymiuk, C.; Ioerger, T.; Balakrishnan, A.; Bryk, R.; Rhee, K.; Sacchettini, J.; Nathan, C.
Comparison of transposon and deletion mutants in Mycobacterium tuberculosis The case of rv1248c, encoding 2-hydroxy-3-oxoadipate synthase
Tuberculosis
95
689-694
2015
BRENDA: Mycobacterium tuberculosis, Mycobacterium tuberculosis CDC1551, Mycobacterium tuberculosis H37Rv
Textmining: transposons, Mus sp.
Damania, P; Sen, B; Dar, SB; Kumar, S; Kumari, A; Gupta, E; Sarin, SK; Venugopal, SK
Hepatitis B Virus Induces Cell Proliferation via HBx-Induced microRNA-21 in Hepatocellular Carcinoma by Targeting Programmed Cell Death Protein4 (PDCD4) and Phosphatase and Tensin Homologue (PTEN).
PLoS One
9
e91745
2014
Hepatitis B virus
Kubasik, NP; Richert, DA; Bloom, RJ; Hsu, RY; Westerfeld, WW
Pyruvate-glyoxylate carboligase activity of the pyruvate dehydrogenase complex of Escherichia coli.
Biochemistry
11
2225-9
1972
Escherichia coli
Danpure, CJ; Purkiss, P; Jennings, PR; Watts, RW
Mitochondrial damage and the subcellular distribution of 2-oxoglutarate:glyoxylate carboligase in normal human and rat liver and in the liver of a patient with primary hyperoxaluria type I.
Clin Sci (Lond)
70
417-25
1986
Homo sapiens, Rattus
Koch, J; Stokstad, EL
Partial purification of a 2-oxo-glutarate:glyoxylate carboligase from rat liver mitochondria.
Biochem Biophys Res Commun
23
585-91
1966
Rattus
KRAKOW, G; BARKULIS, SS; HAYASHI, JA
Glyoxylic acid carboligase: an enzyme present in glycolate-grown Escherichia coli.
J Bacteriol
81
509-18
1961
Escherichia coli
Li, S; Xu, N; Liu, L; Chen, J
Engineering of carboligase activity reaction in Candida glabrata for acetoin production.
Metab Eng
22
32-9
2014
[Candida] glabrata
Wei, Z; Wilkinson, RC; Rashid, GMM; Brown, D; Flp, V; Bugg, TDH
Characterization of Thiamine Diphosphate-Dependent 4-Hydroxybenzoylformate Decarboxylase Enzymes from Rhodococcus jostii RHA1 and Pseudomonas fluorescens Pf-5 Involved in Degradation of Aryl C2 Lignin Degradation Fragments.
Biochemistry
2019
Pseudomonas fluorescens
Rosche, B; Breuer, M; Hauer, B; Rogers, PL
Screening of yeasts for cell-free production of (R)-phenylacetylcarbinol.
Biotechnol Lett
25
841-5
2003
Schizosaccharomyces pombe, Cyberlindnera jadinii, Saccharomyces cerevisiae, Candida tropicalis
Rosche B;Breuer M;Hauer B;Rogers PL
Screening of yeasts for cell-free production of (R)-phenylacetylcarbinol.
Biotechnology letters
25
841-845
2003
Schizosaccharomyces pombe, Cyberlindnera jadinii, Saccharomyces cerevisiae, Candida tropicalis
Aguesse-Germon, S; Liu, SH; Chevallier, M; Pichoud, C; Jamard, C; Borel, C; Chu, CK; Trépo, C; Cheng, YC; Zoulim, F
Inhibitory effect of 2'-fluoro-5-methyl-beta-L-arabinofuranosyl-uracil on duck hepatitis B virus replication.
Antimicrob Agents Chemother
42
369-76
1998
Anas platyrhynchos, Hepatitis B virus, Duck hepatitis B virus, Metazoa, animal
Lin, YC; Chang, JC; Cheng, SY; Wang, CM; Jhan, YL; Lo, IW; Hsu, YM; Liaw, CC; Hwang, CC; Chou, CH
New Bioactive Chromanes from Litchi chinensis.
J Agric Food Chem
63
2472-8
2015
Homo sapiens, Litchi chinensis
Seignères, B; Pichoud, C; Martin, P; Furman, P; Trépo, C; Zoulim, F
Inhibitory activity of dioxolane purine analogs on wild-type and lamivudine-resistant mutants of hepadnaviruses.
Hepatology
36
710-22
2002
Hepatitis B virus, Anas platyrhynchos, Duck hepatitis B virus
Hauschildt, S
The influence of thiamine deficiency on porphyrin synthesis and porphyrin proteins.
J Nutr Sci Vitaminol (Tokyo)
21
403-10
1975
Rattus
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