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Acquired Immunodeficiency Syndrome
1H, 13C, and 15N backbone chemical shift assignments of coronavirus-2 non-structural protein Nsp10.
Acute Kidney Injury
Thrombotic thrombocytopenic purpura in a 2.5-year-old boy with dengue infection: a rare complication.
Anemia
Proteins selectively killing tumor cells.
Arteritis
Arterivirus Nsp1 modulates the accumulation of minus-strand templates to control the relative abundance of viral mRNAs.
Arteritis
Equine arteritis virus non-structural protein 1, an essential factor for viral subgenomic mRNA synthesis, interacts with the cellular transcription co-factor p100.
Arteritis
Nuclear localization of non-structural protein 1 and nucleocapsid protein of equine arteritis virus.
Bluetongue
Atomic structure of the translation regulatory protein NS1 of bluetongue virus.
Bluetongue
Bluetongue virus non-structural protein 1 is a positive regulator of viral protein synthesis.
Bluetongue
Detection of bluetongue virus RNA in cell cultures and in the central nervous system of experimentally infected mice using in situ hybridization.
Bluetongue
Ovine and murine T cell epitopes from the non-structural protein 1 (NS1) of bluetongue virus serotype 8 (BTV-8) are shared among viral serotypes.
Breast Neoplasms
Oncogenic PIK3CA mutations increase dependency on the mRNA cap methyltransferase, RNMT, in breast cancer cells.
Bronchitis
The cellular RNA helicase DDX1 interacts with coronavirus nonstructural protein 14 and enhances viral replication.
Coinfection
A highly conserved region between amino acids 221 and 266 of dengue virus non-structural protein 1 is a major epitope region in infected patients.
Coinfection
Use of whole blood over plasma enhances the detection of dengue virus RNA: possible utility in dengue vaccine trials.
Coma
Thrombotic thrombocytopenic purpura in a 2.5-year-old boy with dengue infection: a rare complication.
COVID-19
Combining SARS-CoV-2 Proofreading Exonuclease and RNA-Dependent RNA Polymerase Inhibitors as a Strategy to Combat COVID-19: A High-Throughput in silico Screening.
COVID-19
Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp14 RNA cap methyltransferase.
COVID-19
Probing the SAM Binding Site of SARS-CoV-2 nsp14 in vitro Using SAM Competitive Inhibitors Guides Developing Selective bi-substrate Inhibitors.
COVID-19
Probing the SAM Binding Site of SARS-CoV-2 Nsp14 In Vitro Using SAM Competitive Inhibitors Guides Developing Selective Bisubstrate Inhibitors.
COVID-19
Repurposing of FDA-Approved Toremifene to Treat COVID-19 by Blocking the Spike Glycoprotein and NSP14 of SARS-CoV-2.
COVID-19
Structure-based virtual screening and molecular dynamics simulation of SARS-CoV-2 Guanine-N7 methyltransferase (nsp14) for identifying antiviral inhibitors against COVID-19.
Dengue
A Haemophilic Dengue Patient with Pleural Effusion and Earache.
Dengue
A highly conserved region between amino acids 221 and 266 of dengue virus non-structural protein 1 is a major epitope region in infected patients.
Dengue
A sensor tip based on carbon nanotube-ink printed electrode for the dengue virus NS1 protein.
Dengue
A serotype-specific epitope of dengue virus 1 identified by phage displayed random peptide library.
Dengue
A thiophene-modified screen printed electrode for detection of dengue virus NS1 protein.
Dengue
Accuracy and efficacy of pre-dengue vaccination screening for previous dengue infection with five commercially available immunoassays: a retrospective analysis of phase 3 efficacy trials.
Dengue
An outbreak of dengue fever in children in the National Capital District of Papua New Guinea in 2016.
Dengue
Antigen production using heterologous expression of dengue virus-2 non-structural protein 1 (NS1) in Nicotiana tabacum (Havana) for immunodiagnostic purposes.
Dengue
Antigenic cell associated dengue 2 virus proteins detected in vitro using dengue fever patients sera.
Dengue
Antiplatelet autoantibodies elicited by dengue virus non-structural protein 1 cause thrombocytopenia and mortality in mice.
Dengue
Applications of a Rapid and Sensitive Dengue DUO Rapid Immunochromatographic Test Kit as a Diagnostic Strategy during a Dengue Type 2 Epidemic in an Urban City.
Dengue
Biochemical characterization of the (nucleoside-2'O)-methyltransferase activity of dengue virus protein NS5 using purified capped RNA oligonucleotides 7MeGpppACn and GpppACn.
Dengue
Bovine serum albumin nanoparticles induce histopathological changes and inflammatory cell recruitment in the skin of treated mice.
Dengue
Case Report: Cardiac Tamponade in Dengue Hemorrhagic Fever: An Unusual Manifestation of a Common Disease.
Dengue
Circulation of dengue serotype 1 viruses during the 2019 outbreak in Dar es Salaam, Tanzania.
Dengue
Clinical Features and Laboratory Findings of Travelers Returning to South Australia with Dengue Virus Infection.
Dengue
Clinical, laboratory, and demographic determinants of hospitalization due to dengue in 7613 patients: A retrospective study based on hierarchical models.
Dengue
Comparative specificity and sensitivity of NS1-based serological assays for the detection of flavivirus immune response.
Dengue
Comparison between polyethylene glycol and zwitterionic polymers as antifouling coatings on wearable devices for selective antigen capture from biological tissue.
Dengue
Comparison of performance of serum and plasma in panbio dengue and Japanese encephalitis virus enzyme-linked immunosorbent assays.
Dengue
Could Homeopathy Become An Alternative Therapy In Dengue Fever? An example Of 10 Case Studies.
Dengue
Cross-Reactivity of Rapid Salmonella Typhi IgM Immunoassay in Dengue Fever Without Co-Existing Infection.
Dengue
Dataset of proteins mapped on HepG2 cells and those differentially abundant after expression of the dengue non-structural 1 protein.
Dengue
Demographic, clinical and laboratory features of leptospirosis and dengue co-infection in Malaysia.
Dengue
Dengue haemorrhagic fever presenting with cholestatic hepatitis: two case reports and a review of literature.
Dengue
Dengue Virus Glycosylation: What Do We Know?
Dengue
Dengue virus infection in a French traveller to the hilly region of Nepal in 2015: a case report.
Dengue
Dengue virus non-structural protein 1 activates the p38 MAPK pathway to decrease barrier integrity in primary human endothelial cells.
Dengue
Dengue Virus Non-structural Protein 1 Modulates Infectious Particle Production via Interaction with the Structural Proteins.
Dengue
Dengue virus non-structural protein 1: a pathogenic factor, therapeutic target, and vaccine candidate.
Dengue
Dengue Virus NS1 Disrupts the Endothelial Glycocalyx, Leading to Hyperpermeability.
Dengue
Dengue virus NS1 protein activates immune cells via TLR4 but not TLR2 or TLR6.
Dengue
Design of SERS nanotags for multiplexed lateral flow immunoassays.
Dengue
Detection of dengue virus NS1 antigen in infected Aedes aegypti using a commercially available kit.
Dengue
Development of a highly sensitive magneto-enzyme lateral flow immunoassay for dengue NS1 detection.
Dengue
Development of a quantitative NS1-capture enzyme-linked immunosorbent assay for early detection of yellow fever virus infection.
Dengue
Development of an anti-Dengue NS1 IgG ELISA to Evaluate Exposure to Dengue Virus.
Dengue
Development of antibody biomarkers of long term and recent dengue virus infections.
Dengue
Development of Bacteriophage Virus-Like Particle Vaccines Displaying Conserved Epitopes of Dengue Virus Non-Structural Protein 1.
Dengue
Development of specific dengue virus 2'-O- and N7-methyltransferase assays for antiviral drug screening.
Dengue
Diagnostic accuracy of 5 different brands of dengue virus non-structural protein 1 (NS1) antigen rapid diagnostic tests (RDT) in Indonesia.
Dengue
DNA vaccine against the non-structural 1 protein (NS1) of dengue 2 virus.
Dengue
Early central nervous system involvement in a young patient with dengue encephalitis.
Dengue
Endocytosis of flavivirus NS1 is required for NS1-mediated endothelial hyperpermeability and is abolished by a single N-glycosylation site mutation.
Dengue
Epidemiology and characteristics of the dengue outbreak in Guangdong, Southern China, in 2014.
Dengue
Evaluation and use of NS1 IgM antibody detection for acute dengue virus diagnosis: report from an outbreak investigation.
Dengue
Evaluation of Adamantane Derivatives as Inhibitors of Dengue Virus mRNA Cap Methyltransferase by Docking and Molecular Dynamics Simulations.
Dengue
Evaluation of commercially available diagnostic tests for the detection of dengue virus NS1 antigen and anti-dengue virus IgM antibody.
Dengue
Evaluation of protective efficacy and immune mechanisms of using a non-structural protein NS1 in DNA vaccine against dengue 2 virus in mice.
Dengue
Evaluation of the importance of fever with respect to dengue prognosis according to the 2009 WHO classification: a retrospective study.
Dengue
External quality assessment of dengue and chikungunya diagnostics in the Asia Pacific region, 2015.
Dengue
Fabrication and Characterization of Simple Structure Fluidic-Based Memristor for Immunosensing of NS1 Protein Application.
Dengue
Fatal Dengue, Chikungunya and Leptospirosis: The Importance of Assessing Co-infections in Febrile Patients in Tropical Areas.
Dengue
Finding small molecules with pan-serotype activity to target Dengue non-structural protein 1.
Dengue
First round of external quality assessment of dengue diagnostics in the WHO Western Pacific Region, 2013.
Dengue
Flaviviral methyltransferase/RNA interaction: structural basis for enzyme inhibition.
Dengue
Gallbladder Wall Thickening for Early Detection of Plasma Leakage in Dengue Infected Adult Patients.
Dengue
Generation of human single-chain variable fragment antibodies specific to dengue virus non-structural protein 1 that interfere with the virus infectious cycle.
Dengue
High-affinity five/six-letter DNA aptamers with superior specificity enabling the detection of dengue NS1 protein variants beyond the serotype identification.
Dengue
High-yield production of short GpppA- and 7MeGpppA-capped RNAs and HPLC-monitoring of methyltransfer reactions at the guanine-N7 and adenosine-2'O positions.
Dengue
Highly sensitive detection of dengue biomarker using streptavidin-conjugated quantum dots.
Dengue
HOSPITAL- AND COMMUNITY- BASED SURVEILLANCE OF ZIKA AND DENGUE VIRUSES IN INDONESIA.
Dengue
IgG1 and IgG4 antibodies against Aedes aegypti salivary proteins and risk for dengue infections.
Dengue
Incidence of dengue illness in Mexican people aged 6 months to 50 years old: A prospective cohort study conducted in Jalisco.
Dengue
Intravenous immunoglobulin therapy for dengue capillary leak syndrome in a renal allograft recipient.
Dengue
Isolation of serotype-specific antibodies against dengue virus non-structural protein 1 using phage display and application in a multiplexed serotyping assay.
Dengue
Kinetics of Dengue Non-Structural Protein 1 Antigen and IgM and IgA Antibodies in Capillary Blood Samples from Confirmed Dengue Patients.
Dengue
Kinetics of non-structural protein 1, IgM and IgG antibodies in dengue type 1 primary infection.
Dengue
Label-free capacitive assaying of biomarkers for molecular diagnostics.
Dengue
Miller Fisher syndrome developing as a parainfectious manifestation of dengue fever: a case report and review of the literature.
Dengue
Modification of S-Adenosyl-l-Homocysteine as Inhibitor of Nonstructural Protein 5 Methyltransferase Dengue Virus Through Molecular Docking and Molecular Dynamics Simulation.
Dengue
Molecular mimicry between virus and host and its implications for dengue disease pathogenesis.
Dengue
Mutagenesis of the dengue virus type 2 NS5 methyltransferase domain.
Dengue
Neutrophil Extracellular Traps in Dengue Are Mainly Generated NOX-Independently.
Dengue
Non-structural protein 1 (NS1) of dengue virus detection correlates with severity in primary but not in secondary dengue infection.
Dengue
NS1-based tests with diagnostic utility for confirming dengue infection: a meta-analysis.
Dengue
Outbreak of severe dengue associated with DENV-3 in the city of Manado, North Sulawesi, Indonesia.
Dengue
Piezoelectric immunochip coated with thin films of bacterial cellulose nanocrystals for dengue detection.
Dengue
Platelet activation and aggregation response to dengue virus nonstructural protein 1 and domains.
Dengue
Precisão e confiabilidade de um teste imuno-cromatográfico rápido NS1 para diagnóstico DENV-1 no ponto de atendimento e no laboratório.
Dengue
Preparation and Application of Yellow Fever Virus NS1 protein-specific Monoclonal Antibodies.
Dengue
Production of recombinant dengue non-structural 1 (NS1) proteins from clinical virus isolates.
Dengue
Protective efficacy of the recombinant, live-attenuated, CYD tetravalent dengue vaccine in Thai schoolchildren: a randomised, controlled phase 2b trial.
Dengue
Protein refolding based on high hydrostatic pressure and alkaline pH: Application on a recombinant dengue virus NS1 protein.
Dengue
Rational selection of hidden epitopes for a molecularly imprinted electrochemical sensor in the recognition of heat-denatured dengue NS1 protein.
Dengue
Retooling phage display with electrohydrodynamic nanomixing and nanopore sequencing.
Dengue
Serological point-of-care and label-free capacitive diagnosis of dengue virus infection.
Dengue
Simultaneous Detection of Dengue NS1 Antigen, IgM plus IgG and Platelet Enumeration during an Outbreak.
Dengue
Spontaneous splenic rupture in dengue fever with non-fatal outcome in an adult.
Dengue
Suboptimal diagnostic performance of dengue non-structural protein 1 antigen rapid test during non-endemic periods in southern Taiwan.
Dengue
Super induction of dengue virus NS1 protein in E. coli.
Dengue
Surface plasmon resonance analysis for detecting non-structural protein 1 of dengue virus in Indonesia.
Dengue
Susceptibility of mouse macrophage J774 to dengue virus infection.
Dengue
Targeting the non-structural protein 1 from dengue virus to a dendritic cell population confers protective immunity to lethal virus challenge.
Dengue
The dengue virus non-structural protein 1 (NS1) is secreted efficiently from infected mosquito cells.
Dengue
The dengue virus non-structural protein 1 (NS1) is secreted from infected mosquito cells via a non-classical caveolin-1-dependent pathway.
Dengue
The diagnostic sensitivity of dengue rapid test assays is significantly enhanced by using a combined antigen and antibody testing approach.
Dengue
The effect of the dengue non-structural 1 protein expression over the HepG2 cell proteins in a proteomic approach.
Dengue
The establishment and clinical evaluation of a novel, rapid, no-wash one-step immunoassay for the detection of dengue virus non-structural protein 1.
Dengue
Thrombotic thrombocytopenic purpura in a 2.5-year-old boy with dengue infection: a rare complication.
Dengue
Toward the identification of viral cap-methyltransferase inhibitors by fluorescence screening assay.
Dengue
Transient Expression of Dengue Virus NS1 Antigen in Nicotiana benthamiana for Use as a Diagnostic Antigen.
Dengue
Two Cases of False-Positive Dengue Non-Structural Protein 1 (NS1) Antigen in Patients with Hematological Malignancies and a Review of the Literature on the Use of NS1 for the Detection of Dengue Infection.
Dengue
Utility of a multiplex real-time polymerase chain reaction for combined detection and serotyping of dengue virus in paediatric patients hospitalised with severe dengue: A report from Chennai.
Dengue
Utility of a Multiplex Real-Time Polymerase Chain Reaction for Combined Detection and Serotyping of Dengue Virus in Paediatric Patients Hospitalised with Severe Dengue: A Report from Chennai.
Dengue
Vimentin interacts with heterogeneous nuclear ribonucleoproteins and dengue nonstructural protein 1 and is important for viral replication and release.
Dengue
[Perinatal Dengue: A case Report].
Encephalitis
Comparison of performance of serum and plasma in panbio dengue and Japanese encephalitis virus enzyme-linked immunosorbent assays.
Encephalitis
Early central nervous system involvement in a young patient with dengue encephalitis.
Encephalitis, Japanese
Comprehensive Mapping Antigenic Epitopes of NS1 Protein of Japanese Encephalitis Virus with Monoclonal Antibodies.
Encephalitis, Japanese
Comprehensive mapping of West Nile virus (WNV)- and Japanese encephalitis virus serocomplex-specific linear B-cell epitopes from WNV non-structural protein 1.
Encephalitis, Japanese
Non-structural protein 1 (NS1) antibody-based assays to differentiate West Nile (WN) virus from Japanese encephalitis virus infections in horses: Effects of WN virus NS1 antibodies induced by inactivated WN vaccine.
Encephalitis, Japanese
Non-structural protein 1 from Japanese encephalitis virus expressed in E. coli retains its molecular weight and immunogenicity.
Encephalitis, Tick-Borne
Antibody responses to tick-borne encephalitis virus non-structural protein 1 and whole virus antigen-a new tool in the assessment of suspected vaccine failure patients.
Encephalitis, Tick-Borne
Comparative specificity and sensitivity of NS1-based serological assays for the detection of flavivirus immune response.
Encephalitis, Tick-Borne
Tick-Borne Encephalitis Virus Vaccines Contain Non-Structural Protein 1 Antigen and may Elicit NS1-Specific Antibody Responses in Vaccinated Individuals.
Enteritis
Cellular microRNA miR-181b inhibits replication of mink enteritis virus by repression of non-structural protein 1 translation.
Exanthema
Cytokine gene polymorphisms associated with symptomatic parvovirus B19 infection.
Flavivirus Infections
A high-throughput and multiplex microsphere immunoassay based on non-structural protein 1 can discriminate three flavivirus infections.
Flavivirus Infections
Development of a quantitative NS1-capture enzyme-linked immunosorbent assay for early detection of yellow fever virus infection.
Gastroenteritis
MUTAGENESIS OF CORONAVIRUS NSP14 REVEALS ITS POTENTIAL ROLE IN MODULATION OF THE INNATE IMMUNE RESPONSE.
Hematologic Neoplasms
Two Cases of False-Positive Dengue Non-Structural Protein 1 (NS1) Antigen in Patients with Hematological Malignancies and a Review of the Literature on the Use of NS1 for the Detection of Dengue Infection.
Hepatitis
Coronaviruses: an RNA proofreading machine regulates replication fidelity and diversity.
Hepatitis
Effects of mutagenesis of murine hepatitis virus nsp1 and nsp14 on replication in culture.
Hepatitis
High Fidelity of Murine Hepatitis Virus Replication Is Decreased in nsp14 Exoribonuclease Mutants.
Hepatitis
Infidelity of SARS-CoV Nsp14-exonuclease mutant virus replication is revealed by complete genome sequencing.
Hepatitis
Murine coronaviruses encoding nsp2 at different genomic loci have altered replication, protein expression, and localization.
Hepatitis
Murine Hepatitis Virus nsp14 Exoribonuclease Activity Is Required for Resistance to Innate Immunity.
Hepatitis
Mutagenesis of S-Adenosyl-l-Methionine-Binding Residues in Coronavirus nsp14 N7-Methyltransferase Demonstrates Differing Requirements for Genome Translation and Resistance to Innate Immunity.
Hepatitis B
Influenza vaccine: progress in a vaccine that elicits a broad immune response.
Hepatitis C
Secretion and purification of hepatitis C virus NS1 glycoprotein produced by recombinant baculovirus-infected insect cells.
Herpes Simplex
RING-Domain E3 Ligase-Mediated Host-Virus Interactions: Orchestrating Immune Responses by the Host and Antagonizing Immune Defense by Viruses.
Infections
A highly conserved region between amino acids 221 and 266 of dengue virus non-structural protein 1 is a major epitope region in infected patients.
Infections
An Attempt Towards Lab And Clinical Combine Appraised, Including Future Concerns Regarding Dengue Infection.
Infections
Antibody responses to tick-borne encephalitis virus non-structural protein 1 and whole virus antigen-a new tool in the assessment of suspected vaccine failure patients.
Infections
Aspects of T Cell-Mediated Immunity Induced in Mice by a DNA Vaccine Based on the Dengue-NS1 Antigen after Challenge by the Intracerebral Route.
Infections
Cellular microRNA miR-181b inhibits replication of mink enteritis virus by repression of non-structural protein 1 translation.
Infections
Comprehensive Mapping Antigenic Epitopes of NS1 Protein of Japanese Encephalitis Virus with Monoclonal Antibodies.
Infections
Comprehensive mapping of West Nile virus (WNV)- and Japanese encephalitis virus serocomplex-specific linear B-cell epitopes from WNV non-structural protein 1.
Infections
Conformational plasticity of the influenza A virus NS1 protein.
Infections
Cytokine gene polymorphisms associated with symptomatic parvovirus B19 infection.
Infections
Dengue haemorrhagic fever presenting with cholestatic hepatitis: two case reports and a review of literature.
Infections
Development of a quantitative NS1-capture enzyme-linked immunosorbent assay for early detection of yellow fever virus infection.
Infections
Development of an anti-Dengue NS1 IgG ELISA to Evaluate Exposure to Dengue Virus.
Infections
Development of antibody biomarkers of long term and recent dengue virus infections.
Infections
Diagnostic accuracy of 5 different brands of dengue virus non-structural protein 1 (NS1) antigen rapid diagnostic tests (RDT) in Indonesia.
Infections
Differentiation of West Nile Virus-Infected Animals from Vaccinated Animals by Competitive ELISA Using Monoclonal Antibodies Against Non-Structural Protein 1.
Infections
Disruption of Src homology 3-binding motif within non-structural protein 1 of influenza B virus unexpectedly enhances viral replication in human cells.
Infections
Distinction between serological responses following tick-borne encephalitis virus (TBEV) infection vs vaccination, Sweden 2017.
Infections
DNA vaccination with the Aleutian mink disease virus NS1 gene confers partial protection against disease.
Infections
Establishment of functional B cell memory against parvovirus B19 capsid proteins may be associated with resolution of persistent infection.
Infections
Ethanolic Extract of Melia Fructus Has Anti-influenza A Virus Activity by Affecting Viral Entry and Viral RNA Polymerase.
Infections
Evaluation of protective efficacy and immune mechanisms of using a non-structural protein NS1 in DNA vaccine against dengue 2 virus in mice.
Infections
Highly sensitive detection of dengue biomarker using streptavidin-conjugated quantum dots.
Infections
IgG1 and IgG4 antibodies against Aedes aegypti salivary proteins and risk for dengue infections.
Infections
In-silico search of virus-specific host microRNAs regulating avian influenza virus NS1 expression.
Infections
Influenza A virus non-structural protein 1 (NS1) interacts with cellular multifunctional protein nucleolin during infection.
Infections
Influenza virus non-structural protein 1 (NS1) disrupts interferon signaling.
Infections
Inhibition of autophagy promotes human RSV NS1-induced inflammation and apoptosis in vitro.
Infections
Isolation of serotype-specific antibodies against dengue virus non-structural protein 1 using phage display and application in a multiplexed serotyping assay.
Infections
Kinetics of non-structural protein 1, IgM and IgG antibodies in dengue type 1 primary infection.
Infections
Miller Fisher syndrome developing as a parainfectious manifestation of dengue fever: a case report and review of the literature.
Infections
Molecular characteristics of the human pandemic influenza A virus (H1N1).
Infections
MUTAGENESIS OF CORONAVIRUS NSP14 REVEALS ITS POTENTIAL ROLE IN MODULATION OF THE INNATE IMMUNE RESPONSE.
Infections
Non-structural protein 1 (NS1) antibody-based assays to differentiate West Nile (WN) virus from Japanese encephalitis virus infections in horses: Effects of WN virus NS1 antibodies induced by inactivated WN vaccine.
Infections
Non-structural protein 1 (NS1) of dengue virus detection correlates with severity in primary but not in secondary dengue infection.
Infections
Non-structural protein 1 from Japanese encephalitis virus expressed in E. coli retains its molecular weight and immunogenicity.
Infections
Non-structural protein 1 from Zika virus: Heterologous expression, purification, and potential for diagnosis of Zika infections.
Infections
Nuclear localization of non-structural protein 1 and nucleocapsid protein of equine arteritis virus.
Infections
Platelet activation and aggregation response to dengue virus nonstructural protein 1 and domains.
Infections
Preparation and Application of Yellow Fever Virus NS1 protein-specific Monoclonal Antibodies.
Infections
Respiratory syncytial virus non-structural protein 1 facilitates virus replication through miR-29a-mediated inhibition of interferon-? receptor.
Infections
Role of mitochondria in parvovirus pathology.
Infections
Salivary Detection of Dengue Virus NS1 Protein with a Label-Free Immunosensor for Early Dengue Diagnosis.
Infections
Screening pipeline for Flavivirus based Inhibitors for Zika Virus NS1.
Infections
Serologic diagnosis of West Nile and St. Louis encephalitis virus infections in domestic chickens.
Infections
Structural Basis for a Novel Interaction between the NS1 Protein Derived from the 1918 Influenza Virus and RIG-I.
Infections
Structure of the Dengue Virus Glycoprotein NS1 by Electron Microscopy and Single Particle Analysis.
Infections
SUMO1 modification of the non-structural protein 1 of influenza A virus.
Infections
Super induction of dengue virus NS1 protein in E. coli.
Infections
Susceptibility of mouse macrophage J774 to dengue virus infection.
Infections
The Central Role of Non-Structural Protein 1 (NS1) in Influenza Biology and Infection.
Infections
The Influenza NS1 Protein: What Do We Know in Equine Influenza Virus Pathogenesis?
Infections
The viral non-structural protein 1 alpha (Nsp1?) inhibits p53 apoptosis activity by increasing murine double minute 2 (mdm2) expression in porcine reproductive and respiratory syndrome virus (PRRSV) early-infected cells.
Infections
Tick-borne encephalitis virus (TBEV): non-structural protein (NS1) IgG ELISA differentiating infection vs. vaccination antibody responses.
Infections
Two Cases of False-Positive Dengue Non-Structural Protein 1 (NS1) Antigen in Patients with Hematological Malignancies and a Review of the Literature on the Use of NS1 for the Detection of Dengue Infection.
Infections
Zika virus as an oncolytic treatment of human neuroblastoma cells requires CD24.
Influenza in Birds
Alleles A and B of non-structural protein 1 of avian influenza A viruses differentially inhibit beta interferon production in human and mink lung cells.
Influenza in Birds
Annexin A2 (ANXA2) interacts with nonstructural protein 1 and promotes the replication of highly pathogenic H5N1 avian influenza virus.
Influenza in Birds
Changes in the NS1 gene of avian influenza viruses isolated in Thailand affect expression of type I interferon in primary chicken embryonic fibroblast cells.
Influenza in Birds
Construction of a human scFv antibody library with VH regions randomized and its application
Influenza in Birds
Construction of a human scFv antibody library with VH regions randomized and its application.
Influenza in Birds
Detection of highly pathogenic avian influenza virus infection in vaccinated chicken flocks by monitoring antibodies against non-structural protein 1 (NS1).
Influenza in Birds
Double-stranded RNA-induced activation of activating protein-1 promoter is differentially regulated by the non-structural protein 1 of avian influenza A viruses.
Influenza in Birds
Effective inhibition of mRNA accumulation and protein expression of H5N1 avian influenza virus NS1 gene in vitro by small interfering RNAs.
Influenza in Birds
Effects of NS1 variants of H5N1 influenza virus on interferon induction, TNFalpha response and p53 activity.
Influenza in Birds
Highly pathogenic avian influenza A virus H5N1 non-structural protein 1 is associated with apoptotic activation of the intrinsic mitochondrial pathway.
Influenza in Birds
Identification of a Highly Conserved Epitope on Avian Influenza Virus Non-Structural Protein 1 Using a Peptide Microarray.
Influenza in Birds
Mechanism of a Mutation in Non-Structural Protein 1 Inducing High Pathogenicity of Avian Influenza Virus H5N1.
Influenza in Birds
MicroRNA expression profiles from HEK293 cells expressing H5N1 avian influenza virus non-structural protein 1.
Influenza in Birds
Non-structural protein 1 from avian influenza virus H9N2 is an efficient RNA silencing suppressor with characteristics that differ from those of Tomato bushy stunt virus p19.
Influenza in Birds
Non-structural protein 1 of avian influenza A viruses differentially inhibit NF-?B promoter activation.
Influenza in Birds
Preferential Selection and Contribution of Non-Structural Protein 1 (NS1) to the Efficient Transmission of Panzootic Avian Influenza H5N8 Virus Clades 2.3.4.4A and B in Chickens and Ducks.
Influenza in Birds
The C-terminus of non-structural protein 1 (NS1) in H5N8 clade 2.3.4.4 avian influenza virus affects virus fitness in human cells and virulence in mice.
Influenza in Birds
Viral-Host Interactome Analysis Reveals Chicken STAU2 Interacts With Non-structural Protein 1 and Promotes the Replication of H5N1 Avian Influenza Virus.
Influenza, Human
A novel RNA-binding motif in influenza A virus non-structural protein 1.
Influenza, Human
A NS1-binding monoclonal antibody interacts with two residues that are highly conserved in seasonal as well as newly emerged influenza A virus.
Influenza, Human
A Promising IFN-Deficient System to Manufacture IFN-Sensitive Influenza Vaccine Virus.
Influenza, Human
A single point mutation (Y89F) within the non-structural protein 1 of influenza A viruses limits epithelial cell tropism and virulence in mice.
Influenza, Human
Acetylation at K108 of the NS1 protein is important for the replication and virulence of influenza virus.
Influenza, Human
Alanine substitutions within a linker region of the influenza A virus non-structural protein 1 alter its subcellular localization and attenuate virus replication.
Influenza, Human
Alleles A and B of non-structural protein 1 of avian influenza A viruses differentially inhibit beta interferon production in human and mink lung cells.
Influenza, Human
Altering Intracellular Localization of the RNA Interference Factors by Influenza A Virus Non-structural Protein 1.
Influenza, Human
Amino acid substitution K186E in the canine influenza virus H3N8 NS1 protein restores its ability to inhibit host gene expression.
Influenza, Human
Analysis of influenza A virus NS1 dimer interfaces in solution by pulse EPR distance measurements.
Influenza, Human
Analysis of the PDZ binding specificities of Influenza A virus NS1 proteins.
Influenza, Human
Avian influenza viruses inhibit the major cellular signalling integrator c-Abl.
Influenza, Human
Biochemical and structural characterization of the interface mediating interaction between the influenza A virus non-structural protein-1 and a monoclonal antibody.
Influenza, Human
Conformational plasticity of the influenza A virus NS1 protein.
Influenza, Human
Conserved surface features form the double-stranded RNA binding site of non-structural protein 1 (NS1) from influenza A and B viruses.
Influenza, Human
Critical Role of an Antiviral Stress Granule Containing RIG-I and PKR in Viral Detection and Innate Immunity.
Influenza, Human
CRK adaptor protein expression is required for efficient replication of avian influenza A viruses and controls JNK-mediated apoptotic responses.
Influenza, Human
Definition of a human T cell epitope from influenza A non-structural protein 1 using HLA-A2.1 transgenic mice.
Influenza, Human
Design, synthesis, and evaluation of novel small molecule inhibitors of the influenza virus protein NS1.
Influenza, Human
Dimer Interface of the Effector Domain of Non-structural Protein 1 from Influenza A Virus: AN INTERFACE WITH MULTIPLE FUNCTIONS.
Influenza, Human
Discovery of novel influenza inhibitors targeting the interaction of dsRNA with the NS1 protein by structure-based virtual screening.
Influenza, Human
Disruption of Src homology 3-binding motif within non-structural protein 1 of influenza B virus unexpectedly enhances viral replication in human cells.
Influenza, Human
Double-stranded RNA-induced activation of activating protein-1 promoter is differentially regulated by the non-structural protein 1 of avian influenza A viruses.
Influenza, Human
Effects of the S42 residue of the H1N1 swine influenza virus NS1 protein on interferon responses and virus replication.
Influenza, Human
Exploring naphthyl-carbohydrazides as inhibitors of influenza A viruses.
Influenza, Human
Functional Characterization and Direct Comparison of Influenza A, B, C, and D NS1 Proteins in vitro and in vivo.
Influenza, Human
Generation and characterization of a new panel of broadly reactive anti-NS1 mAbs for detection of influenza A virus.
Influenza, Human
Genome-wide CRISPR screen identifies host dependency factors for influenza A virus infection.
Influenza, Human
Genomic and protein structural maps of adaptive evolution of human influenza A virus to increased virulence in the mouse.
Influenza, Human
Heterologous interactions between NS1 proteins from different influenza A virus subtypes/strains.
Influenza, Human
Identification of NS1 domains of avian H5N1 influenza virus which influence the interaction with the NOLC1 protein.
Influenza, Human
Impairment of the Staufen1-NS1 interaction reduces influenza viral replication.
Influenza, Human
Induction of protective class I MHC-restricted CTL in mice by a recombinant influenza vaccine in aluminium hydroxide adjuvant.
Influenza, Human
Influenza A H3N2 subtype virus NS1 protein targets into the nucleus and binds primarily via its C-terminal NLS2/NoLS to nucleolin and fibrillarin.
Influenza, Human
Influenza A virus inhibits type I IFN signaling via NF-kappaB-dependent induction of SOCS-3 expression.
Influenza, Human
Influenza A virus non-structural protein 1 (NS1) interacts with cellular multifunctional protein nucleolin during infection.
Influenza, Human
Influenza A virus NS1 optimises virus infectivity by enhancing genome packaging in a dsRNA-binding dependent manner.
Influenza, Human
Influenza A virus protein NS1 exhibits strain-independent conformational plasticity.
Influenza, Human
Influenza B virus non-structural protein 1 counteracts ISG15 antiviral activity by sequestering ISGylated viral proteins.
Influenza, Human
Influenza vaccine: progress in a vaccine that elicits a broad immune response.
Influenza, Human
Influenza virus non-structural protein 1 (NS1) disrupts interferon signaling.
Influenza, Human
Influenza virus NS1- C/EBP? gene regulatory complex inhibits RIG-I transcription.
Influenza, Human
Large-scale analysis of Influenza A virus sequences reveals potential drug-target sites of NS proteins.
Influenza, Human
Messenger RNA translation enhancement by immune evasion proteins: a comparative study between EKB (vaccinia virus) and NS1 (influenza A virus).
Influenza, Human
Molecular characteristics of the human pandemic influenza A virus (H1N1).
Influenza, Human
Molecular mechanism of influenza A NS1-mediated TRIM25 recognition and inhibition.
Influenza, Human
Mutations associated with severity of the pandemic influenza A(H1N1)pdm09 in humans: a systematic review and meta-analysis of epidemiological evidence.
Influenza, Human
Non-linear enhancement of mRNA delivery efficiencies by influenza A derived NS1 protein engendering host gene inhibition property.
Influenza, Human
Non-structural protein 1 from avian influenza virus H9N2 is an efficient RNA silencing suppressor with characteristics that differ from those of Tomato bushy stunt virus p19.
Influenza, Human
Non-structural protein 1 of H3N2 influenza A virus induces nucleolar stress via interaction with nucleolin.
Influenza, Human
Non-structural protein 1 of influenza viruses inhibits rapid mRNA degradation mediated by double-stranded RNA-binding protein, staufen1.
Influenza, Human
NS1-binding protein abrogates the elevation of cell viability by the influenza A virus NS1 protein in association with CRKL.
Influenza, Human
Phosphorylation of Influenza A virus NS1 protein at threonine 49 suppresses its interferon antagonistic activity.
Influenza, Human
Polymorphism of the NS1 proteins of type A influenza virus.
Influenza, Human
Prophylactic protection against respiratory viruses conferred by a prototype live attenuated influenza virus vaccine.
Influenza, Human
Prophylactic Protection Against Respiratory Viruses Conferred by a Prototype Live Attenuated Influenza Virus Vaccine.
Influenza, Human
Protein clustering and RNA phylogenetic reconstruction of the influenza a virus NS1 protein allow an update in classification and identification of motif conservation.
Influenza, Human
Recovery of TRIM25-Mediated RIG-I Ubiquitination through Suppression of NS1 by RNA Aptamers.
Influenza, Human
Replication-Competent ?NS1 Influenza A Viruses Expressing Reporter Genes.
Influenza, Human
Residues F103 and M106 within the influenza A virus NS1 CPSF4-binding region regulate interferon-stimulated gene translation initiation.
Influenza, Human
Role of c-Jun terminal kinase (JNK) activation in influenza A virus-induced autophagy and replication.
Influenza, Human
Single-stranded DNA aptamer that specifically binds to the influenza virus NS1 protein suppresses interferon antagonism.
Influenza, Human
Structural Basis for a Novel Interaction between the NS1 Protein Derived from the 1918 Influenza Virus and RIG-I.
Influenza, Human
Structural basis for influenza virus NS1 protein block of mRNA nuclear export.
Influenza, Human
Structure and Function of the Influenza A Virus Non-Structural Protein 1.
Influenza, Human
Study on the Mechanisms of Active Compounds in Traditional Chinese Medicine for the Treatment of Influenza Virus by Virtual Screening.
Influenza, Human
SUMO1 modification of the non-structural protein 1 of influenza A virus.
Influenza, Human
Suppression of the antiviral response by an influenza histone mimic.
Influenza, Human
Synthesis and evaluation of quinoxaline derivatives as potential influenza NS1A protein inhibitors.
Influenza, Human
The C-Terminal Effector Domain of Non-Structural Protein 1 of Influenza A Virus Blocks IFN-? Production by Targeting TNF Receptor-Associated Factor 3.
Influenza, Human
The C-terminus of non-structural protein 1 (NS1) in H5N8 clade 2.3.4.4 avian influenza virus affects virus fitness in human cells and virulence in mice.
Influenza, Human
The Central Role of Non-Structural Protein 1 (NS1) in Influenza Biology and Infection.
Influenza, Human
The functional impairment of natural killer cells during influenza virus infection.
Influenza, Human
The Influenza NS1 Protein: What Do We Know in Equine Influenza Virus Pathogenesis?
Influenza, Human
The NS1 Protein: A Multitasking Virulence Factor.
Influenza, Human
Threonine 80 phosphorylation of non-structural protein 1 regulates the replication of influenza A virus by reducing the binding affinity with RIG-I.
Influenza, Human
TRIM25 and DEAD-Box RNA Helicase DDX3X Cooperate to Regulate RIG-I-Mediated Antiviral Immunity.
Influenza, Human
Virtual screening of potential inhibitors from TCM for the CPSF30 binding site on the NS1A protein of influenza A virus.
Kidney Failure, Chronic
Thrombotic thrombocytopenic purpura in a 2.5-year-old boy with dengue infection: a rare complication.
Leukopenia
Miller Fisher syndrome developing as a parainfectious manifestation of dengue fever: a case report and review of the literature.
Melanoma
Proteins selectively killing tumor cells.
Mumps
Development of Improved Mumps Vaccine Candidates by Mutating Viral mRNA Cap Methyltransferase Sites in the Large Polymerase Protein.
Neoplasms
Detection and a possible link between parvovirus B19 and thyroid cancer.
Neoplasms
Molecular characteristics of the human pandemic influenza A virus (H1N1).
Neoplasms
Non-Structural protein 1 (NS1) gene of Canine Parvovirus-2 regresses chemically induced skin tumors in Wistar rats.
Neoplasms
Porcine reproductive and respiratory syndrome virus non-structural protein 1 suppresses tumor necrosis factor-alpha promoter activation by inhibiting NF-?B and Sp1.
Neoplasms
Proteins selectively killing tumor cells.
Parasitemia
The mRNA cap methyltransferase gene TbCMT1 is not essential in vitro but is a virulence factor in vivo for bloodstream form Trypanosoma brucei.
Persistent Infection
Caspase-mediated cleavage of murine norovirus NS1/2 potentiates apoptosis and is required for persistent infection of intestinal epithelial cells.
Porcine Reproductive and Respiratory Syndrome
Amino acid residues in the non-structural protein 1 of porcine reproductive and respiratory syndrome virus involved in down-regulation of TNF-? expression in vitro and attenuation in vivo.
Porcine Reproductive and Respiratory Syndrome
Identification of amino acid residues important for anti-IFN activity of porcine reproductive and respiratory syndrome virus non-structural protein 1.
Porcine Reproductive and Respiratory Syndrome
Modulation of type I interferon induction by porcine reproductive and respiratory syndrome virus and degradation of CREB-binding protein by non-structural protein 1 in MARC-145 and HeLa cells.
Porcine Reproductive and Respiratory Syndrome
Porcine reproductive and respiratory syndrome virus non-structural protein 1 suppresses tumor necrosis factor-alpha promoter activation by inhibiting NF-?B and Sp1.
Porcine Reproductive and Respiratory Syndrome
The viral non-structural protein 1 alpha (Nsp1?) inhibits p53 apoptosis activity by increasing murine double minute 2 (mdm2) expression in porcine reproductive and respiratory syndrome virus (PRRSV) early-infected cells.
Porcine Reproductive and Respiratory Syndrome
Transcriptome analysis of pig macrophages expressing porcine reproductive and respiratory syndrome virus non-structural protein 1.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Establishment of functional B cell memory against parvovirus B19 capsid proteins may be associated with resolution of persistent infection.
Purpura, Thrombotic Thrombocytopenic
Thrombotic thrombocytopenic purpura in a 2.5-year-old boy with dengue infection: a rare complication.
Severe Acute Respiratory Syndrome
Biochemical characterization of exoribonuclease encoded by SARS coronavirus.
Severe Acute Respiratory Syndrome
Characterization of the guanine-N7 methyltransferase activity of coronavirus nsp14 on nucleotide GTP.
Severe Acute Respiratory Syndrome
Expression, purification and characterization of recombinant severe acute respiratory syndrome coronavirus non-structural protein 1.
Severe Acute Respiratory Syndrome
Functional screen reveals SARS coronavirus nonstructural protein nsp14 as a novel cap N7 methyltransferase.
Severe Acute Respiratory Syndrome
High Fidelity of Murine Hepatitis Virus Replication Is Decreased in nsp14 Exoribonuclease Mutants.
Severe Acute Respiratory Syndrome
Structural and molecular basis of mismatch correction and ribavirin excision from coronavirus RNA.
Severe Acute Respiratory Syndrome
Structural basis and functional analysis of the SARS coronavirus nsp14-nsp10 complex.
Severe Acute Respiratory Syndrome
Synthesis in Escherichia coli cells and characterization of the active exoribonuclease of severe acute respiratory syndrome coronavirus.
Severe Acute Respiratory Syndrome
The cellular RNA helicase DDX1 interacts with coronavirus nonstructural protein 14 and enhances viral replication.
Severe Acute Respiratory Syndrome
[Synthesis in Escherichia coli cells and characterization of the active exoribonuclease of severe acute respiratory syndrome coronavirus]
Severe Dengue
Avian anti-NS1 IgY antibodies neutralize dengue virus infection and protect against lethal dengue virus challenge.
Severe Dengue
Case Report: Cardiac Tamponade in Dengue Hemorrhagic Fever: An Unusual Manifestation of a Common Disease.
Severe Dengue
Pathogenesis of Dengue: Dawn of a New Era.
Severe Dengue
Platelet activation and aggregation response to dengue virus nonstructural protein 1 and domains.
Severe Dengue
Recent advances in understanding dengue.
Thrombocytopenia
Antiplatelet autoantibodies elicited by dengue virus non-structural protein 1 cause thrombocytopenia and mortality in mice.
Thrombocytopenia
Miller Fisher syndrome developing as a parainfectious manifestation of dengue fever: a case report and review of the literature.
Thrombocytopenia
Platelet activation and aggregation response to dengue virus nonstructural protein 1 and domains.
Thrombotic Microangiopathies
Thrombotic thrombocytopenic purpura in a 2.5-year-old boy with dengue infection: a rare complication.
Vaccinia
Definition of a human T cell epitope from influenza A non-structural protein 1 using HLA-A2.1 transgenic mice.
Vaccinia
Effects of alanine cluster mutations in the D12 subunit of vaccinia virus mRNA (guanine-N7) methyltransferase.
Vaccinia
Genetic analysis of poxvirus mRNA cap methyltransferase: suppression of conditional mutations in the stimulatory D12 subunit by second-site mutations in the catalytic D1 subunit.
Vaccinia
Messenger RNA translation enhancement by immune evasion proteins: a comparative study between EKB (vaccinia virus) and NS1 (influenza A virus).
Vaccinia
Mutational analysis of vaccinia virus mRNA cap (guanine-N7) methyltransferase reveals essential contributions of the N-terminal peptide that closes over the active site.
Vaccinia
Poxvirus mRNA cap methyltransferase. Bypass of the requirement for the stimulatory subunit by mutations in the catalytic subunit and evidence for intersubunit allostery.
Vaccinia
Structure-function analysis of vaccinia virus mRNA cap (guanine-N7) methyltransferase.
Vaccinia
Synthesis of mRNA guanylyltransferase and mRNA methyltransferases in cells infected with vaccinia virus.
Vaccinia
Yeast mRNA cap methyltransferase is a 50-kilodalton protein encoded by an essential gene.
Vesicular Stomatitis
Amino acid residues within conserved domain VI of the vesicular stomatitis virus large polymerase protein essential for mRNA cap methyltransferase activity.
Vesicular Stomatitis
Identification of a new region in the vesicular stomatitis virus L polymerase protein which is essential for mRNA cap methylation.
Vesicular Stomatitis
Influenza vaccine: progress in a vaccine that elicits a broad immune response.
Viremia
Dengue in travelers: kinetics of viremia and NS1 antigenemia and their associations with clinical parameters.
Viremia
Virological and Immunological Outcomes in Rhesus Monkeys after Exposure to Dengue Virus-Infected Aedes aegypti Mosquitoes.
Virus Diseases
Added value of IgA antibodies against Zika virus non-structural protein 1 in the diagnosis of acute Zika virus infections.
Virus Diseases
Classification of salivary based NS1 from Raman Spectroscopy with support vector machine.
Virus Diseases
Detection of highly pathogenic avian influenza virus infection in vaccinated chicken flocks by monitoring antibodies against non-structural protein 1 (NS1).
Virus Diseases
Development of an anti-Dengue NS1 IgG ELISA to Evaluate Exposure to Dengue Virus.
Virus Diseases
Emetine, a potent alkaloid for the treatment of SARS-CoV-2 targeting papain-like protease and non-structural proteins: pharmacokinetics, molecular docking and dynamic studies.
Virus Diseases
Evaluation and use of NS1 IgM antibody detection for acute dengue virus diagnosis: report from an outbreak investigation.
Virus Diseases
Impairment of the Staufen1-NS1 interaction reduces influenza viral replication.
Virus Diseases
Mutagenesis of S-Adenosyl-l-Methionine-Binding Residues in Coronavirus nsp14 N7-Methyltransferase Demonstrates Differing Requirements for Genome Translation and Resistance to Innate Immunity.
Virus Diseases
Non-structural protein 1 (NS1) antibody-based assays to differentiate West Nile (WN) virus from Japanese encephalitis virus infections in horses: Effects of WN virus NS1 antibodies induced by inactivated WN vaccine.
Virus Diseases
Phosphorylation of Influenza A virus NS1 protein at threonine 49 suppresses its interferon antagonistic activity.
Virus Diseases
Prophylactic protection against respiratory viruses conferred by a prototype live attenuated influenza virus vaccine.
Virus Diseases
Prophylactic Protection Against Respiratory Viruses Conferred by a Prototype Live Attenuated Influenza Virus Vaccine.
Virus Diseases
The Central Role of Non-Structural Protein 1 (NS1) in Influenza Biology and Infection.
West Nile Fever
Non-structural protein 1 (NS1) antibody-based assays to differentiate West Nile (WN) virus from Japanese encephalitis virus infections in horses: Effects of WN virus NS1 antibodies induced by inactivated WN vaccine.
West Nile Fever
Serologic diagnosis of West Nile and St. Louis encephalitis virus infections in domestic chickens.
Yellow Fever
Development and Clinical Evaluation of a Rapid Diagnostic Test for Yellow Fever Non-Structural Protein 1.
Zika Virus Infection
Added value of IgA antibodies against Zika virus non-structural protein 1 in the diagnosis of acute Zika virus infections.
Zika Virus Infection
Zika Virus Antibody Titers Three Years after Confirmed Infection.
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2.1.1.56 mRNA (guanine-N7)-methyltransferase
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The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable). 
