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Information on EC 2.1.1.163 - demethylmenaquinone methyltransferase and Organism(s) Pseudomonas aeruginosa

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EC Tree
     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.163 demethylmenaquinone methyltransferase
IUBMB Comments
The enzyme catalyses the last step in menaquinone biosynthesis. It is able to accept substrates with varying polyprenyl side chain length (the chain length is determined by polyprenyl diphosphate synthase). The enzyme from Escherichia coli also catalyses the conversion of 2-methoxy-6-octaprenyl-1,4-benzoquinone to 5-methoxy-2-methyl-3-octaprenyl-1,4-benzoquinone during the biosynthesis of ubiquinone . The enzyme probably acts on menaquinol rather than menaquinone.
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Pseudomonas aeruginosa
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The taxonomic range for the selected organisms is: Pseudomonas aeruginosa
The expected taxonomic range for this enzyme is: Bacteria, Archaea, Eukaryota
Synonyms
demethylmenaquinone methyltransferase, dmkt1, 2-heptaprenyl-1,4-naphthoquinone methyltransferase, dmth protein, more
SYSTEMATIC NAME
IUBMB Comments
S-adenosyl-L-methione:demethylmenaquinone methyltransferase
The enzyme catalyses the last step in menaquinone biosynthesis. It is able to accept substrates with varying polyprenyl side chain length (the chain length is determined by polyprenyl diphosphate synthase)[1]. The enzyme from Escherichia coli also catalyses the conversion of 2-methoxy-6-octaprenyl-1,4-benzoquinone to 5-methoxy-2-methyl-3-octaprenyl-1,4-benzoquinone during the biosynthesis of ubiquinone [4]. The enzyme probably acts on menaquinol rather than menaquinone.
CAS REGISTRY NUMBER
COMMENTARY hide
37259-80-6
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UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
A0A8G7FQL5_PSEAI
256
0
28312
TrEMBL
-
A0A8G3ZTD7_PSEAI
256
0
28282
TrEMBL
-
A0A3S0KJA9_PSEAI
256
0
28197
TrEMBL
-
A0A8G4AJJ0_PSEAI
256
0
28212
TrEMBL
-
A0A071KVS3_PSEAI
256
0
28254
TrEMBL
-
A0A451GFE5_PSEAI
256
0
28253
TrEMBL
-
A0A8G2ZDM9_PSEAI
256
0
28194
TrEMBL
-
A0A643ECS7_PSEAI
256
0
28297
TrEMBL
-
A0A2R3ILS2_PSEAI
256
0
28213
TrEMBL
-