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Information on EC 1.8.1.7 - glutathione-disulfide reductase

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EC Tree
IUBMB Comments
A dimeric flavoprotein (FAD); activity is dependent on a redox-active disulfide in each of the active centres.
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Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
glutathione reductase, gsh reductase, gssg reductase, glutathione disulfide reductase, ptgr2, gsr-1, glutathione-disulfide reductase, glutathione s-reductase, thioredoxin/glutathione reductase, trxr3, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2 glutathione + NADP+ = glutathione disulfide + NADPH + H+
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