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Information on EC 1.5.5.1 - electron-transferring-flavoprotein dehydrogenase and Organism(s) Arabidopsis thaliana

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EC Tree
IUBMB Comments
An iron-sulfur flavoprotein, forming part of the mitochondrial electron-transfer system.
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This record set is specific for:
Arabidopsis thaliana
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Word Map
The taxonomic range for the selected organisms is: Arabidopsis thaliana
The enzyme appears in selected viruses and cellular organisms
Synonyms
electron transfer flavoprotein, etfdh, etf-qo, etf:qo, electron transfer flavoprotein dehydrogenase, electron transfer flavoprotein-ubiquinone oxidoreductase, etf dehydrogenase, etf-ubiquinone oxidoreductase, electron transfer flavoprotein:ubiquinone oxidoreductase, electron-transferring-flavoprotein dehydrogenase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
electron flavoprotein reductase
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electron transfer flavoprotein dehydrogenase
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electron transfer flavoprotein Q oxidoreductase
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electron transfer flavoprotein-ubiquinone oxidoreductase
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electron-transfer flavoprotein:ubiquinone oxidoreductase
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Electron-transferring-flavoprotein dehydrogenase
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ETF dehydrogenase
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ETF-QO
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ETF-ubiquinone oxidoreductase
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ETF:ubiquinone oxidoreductase
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
oxidation
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redox reaction
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reduction
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PATHWAY SOURCE
PATHWAYS
SYSTEMATIC NAME
IUBMB Comments
electron-transferring-flavoprotein:ubiquinone oxidoreductase
An iron-sulfur flavoprotein, forming part of the mitochondrial electron-transfer system.
CAS REGISTRY NUMBER
COMMENTARY hide
86551-03-3
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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
reduced electron-transferring flavoprotein + ubiquinone
electron-transferring flavoprotein + ubiquinol
show the reaction diagram
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-
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?
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
reduced electron-transferring flavoprotein + ubiquinone
electron-transferring flavoprotein + ubiquinol
show the reaction diagram
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-
-
-
?
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
malfunction
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evaluations of the mutant phenotypes following carbon starvation induced by extended darkness identify similarities to those exhibited by mutants of the ETF/ETFQO complex, metabolic profiling, overview
metabolism
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both isovaleryl-CoA dehydrogenase and 2-hydroxyglutarate dehydrogenase act as electron donors to the ubiquinol pool via an ETF/ETFQO-mediated route, overview. The ETF/ETFQO system can be regarded as a branch of the electron transport system with multiple input sites from seven acyl-CoA dehydrogenases and two N-methyl dehydrogenases, namely, isovaleryl-CoA dehydrogenase and 2-methyl branched-chain acyl-CoA dehydrogenase, as well as glutaryl-CoA dehydrogenase and sarcosine and dimethylglycine dehydrogenases
physiological function
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the functional electron-transfer flavoprotein/electron-transfer flavoprotein:ubiquinone oxidoreductase (ETF/ETFQO) complex supports respiration during carbon starvation. The enzyme is involved in the process of dark-induced senescence
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
ETFQO_ARATH
633
0
70128
Swiss-Prot
Chloroplast (Reliability: 3)
A0A178VYB8_ARATH
633
0
70128
TrEMBL
Chloroplast (Reliability: 3)
Q8L847_ARATH
401
0
44172
TrEMBL
Chloroplast (Reliability: 3)
A0A1P8B0T2_ARATH
584
0
64713
TrEMBL
Chloroplast (Reliability: 3)
A0A654F6R0_ARATH
633
0
70114
TrEMBL
Chloroplast (Reliability: 3)
A0A178W158_ARATH
246
0
27643
TrEMBL
Secretory Pathway (Reliability: 4)
A0A178W0J2_ARATH
401
0
44172
TrEMBL
Chloroplast (Reliability: 3)
A0A7G2EG01_ARATH
594
0
65495
TrEMBL
Chloroplast (Reliability: 3)
PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
additional information
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Ishizaki, K.; Larson, T.R.; Schauer, N.; Fernie, A.R.; Graham, I.A.; Leaver, C.J.
The critical role of Arabidopsis electron-transfer flavoprotein:ubiquinone oxidoreductase during dark-induced starvation
Plant Cell
17
2587-2600
2005
Arabidopsis thaliana
Manually annotated by BRENDA team
Araujo, W.L.; Ishizaki, K.; Nunes-Nesi, A.; Larson, T.R.; Tohge, T.; Krahnert, I.; Witt, S.; Obata, T.; Schauer, N.; Graham, I.A.; Leaver, C.J.; Fernie, A.R.
Identification of the 2-hydroxyglutarate and isovaleryl-CoA dehydrogenases as alternative electron donors linking lysine catabolism to the electron transport chain of Arabidopsis mitochondria
Plant Cell
22
1549-1563
2010
Arabidopsis thaliana
Manually annotated by BRENDA team