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Information on EC 1.5.1.15 - methylenetetrahydrofolate dehydrogenase (NAD+) and Organism(s) Homo sapiens
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EC Tree
1.5.1.15 methylenetetrahydrofolate dehydrogenase (NAD+)Specify your search results
Word Map
- 1.5.1.15
- homocysteine
- women
-
case-control
- hyperhomocysteinemia
- leiden
- thrombosis
- artery
-
folic
- prothrombin
-
meta-analysis
- cardiovascular
- pregnancy
- thrombophilias
- venous
- children
-
homozygote
-
ethnic
- stroke
- coronary
-
caucasian
-
pcr-rflp
-
smoking
-
homozygosity
- thromboembolism
-
one-carbon
-
prothrombotic
- methotrexate
- thymidylate
-
anticoagulant
-
pubmed
-
thermolabile
-
embase
-
hypercoagulable
- pai-1
-
remethylation
- 5-methyltetrahydrofolate
-
gene-gene
- antithrombin
-
pharmacogenetic
- cystathionine
- beta-synthase
-
antiphospholipid
-
reaction-restriction
- miscarriage
- medicine
-
fxiii
-
hypofibrinolysis
- homocystinuria
-
anticardiolipin
-
folate-dependent
- hinfi
The taxonomic range for the selected organisms is: Homo sapiens
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
Reaction Schemes
Synonyms
mthfr, methylenetetrahydrofolate reductase, nmdmc, methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase, mthfr1, mthfr2, methylenetetrahydrofolate dehydrogenase-cyclohydrolase, msmeg_6596, msmeg_6649, nad-dependent dehydrogenase-cyclohydrolase, 
more
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SYNONYM 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase
-
-
methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase
-
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
oxidation
-
-
-
-
redox reaction
-
-
-
-
reduction
-
-
-
-
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SYSTEMATIC NAME
IUBMB Comments
5,10-methylenetetrahydrofolate:NAD+ oxidoreductase
-
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CAS REGISTRY NUMBER
COMMENTARY
82062-90-6
-
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SUBSTRATE
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
5,10-methylenetetrahydrofolate + NAD+
5,10-methenyltetrahydrofolate + NADH
-
-
-
?
5,10-methylenetetrahydropteroylglutamate + NAD+
5,10-methenyltetrahydropteroylglutamate + NADH + H+
5,10-methylenetetrahydropteroylglutamate + NADP+
5,10-methenyltetrahydropteroylglutamate + NADPH + H+
5,10-methylenetetrahydropteroylpentaglutamate + NAD+
5,10-methenyltetrahydropteroylpentaglutamate + NADH + H+
5,10-methylenetetrahydropteroylpentaglutamate + NADP+
5,10-methenyltetrahydropteroylpentaglutamate + NADPH + H+
L-5,10-methenyl-tetrahydrofolate + NADH
L-5,10-methylenetetrahydrofolate + NAD+
-
-
-
-
r
L-5,10-methylenetetrahydrofolate + NAD+
5,10-methenyl-tetrahydrofolate + NADH
-
-
-
-
r
5,10-methylenetetrahydrofolate + NADP+
5,10-methenyltetrahydrofolate + NADPH + H+
-
-
-
?
5,10-methylenetetrahydrofolate + NADP+
5,10-methenyltetrahydrofolate + NADPH + H+
-
?
-
-
5,10-methylenetetrahydrofolate + NADP+
5,10-methenyltetrahydrofolate + NADPH + H+
about 15% of the rate with NAD+
-
-
?
5,10-methylenetetrahydropteroylglutamate + NAD+
5,10-methenyltetrahydropteroylglutamate + NADH + H+
NAD+-dependent dehydrogenase activity of MTHFD2 is 8.5fold higher than its NADP+-dependent activity
-
-
?
5,10-methylenetetrahydropteroylglutamate + NAD+
5,10-methenyltetrahydropteroylglutamate + NADH + H+
NAD+-dependent dehydrogenase activity of MTHFD2L is 3.4fold higher than its NADP+-dependent activity under saturating substrate conditions
-
-
?
5,10-methylenetetrahydropteroylglutamate + NADP+
5,10-methenyltetrahydropteroylglutamate + NADPH + H+
NAD+-dependent dehydrogenase activity of MTHFD2 is 8.5fold higher than its NADP+-dependent activity
-
-
?
5,10-methylenetetrahydropteroylglutamate + NADP+
5,10-methenyltetrahydropteroylglutamate + NADPH + H+
NAD+-dependent dehydrogenase activity of MTHFD2L is 3.4fold higher than its NADP+-dependent activity under saturating substrate conditions
-
-
?
5,10-methylenetetrahydropteroylpentaglutamate + NAD+
5,10-methenyltetrahydropteroylpentaglutamate + NADH + H+
NAD+-dependent dehydrogenase activity of MTHFD2 with the substrate 5,10-methylenetetrahydropteroylglutamate is 8.5fold higher than its NADP+-dependent activity. While the NAD+-dependent activity of MTHFD2 slightly decreases, its maximal NADP+-dependent activity considerably increases with 5,10-methylenetetrahydropteroylpentaglutamate compared to 5,10-methylenetetrahydropteroylglutamate
-
-
?
5,10-methylenetetrahydropteroylpentaglutamate + NAD+
5,10-methenyltetrahydropteroylpentaglutamate + NADH + H+
NAD+-dependent dehydrogenase activity of MTHFD2L with the substrate 5,10-methylenetetrahydropteroylglutamate is 3.4fold higher than its NADP+-dependent activity under saturating substrate conditions. While the NAD+-dependent activity of MTHFD2 slightly decreases, its maximal NADP+-dependent activity considerably increases with 5,10-methylenetetrahydropteroylpentaglutamate compared to 5,10-methylenetetrahydropteroylglutamate
-
-
?
5,10-methylenetetrahydropteroylpentaglutamate + NADP+
5,10-methenyltetrahydropteroylpentaglutamate + NADPH + H+
NAD+-dependent dehydrogenase activity of MTHFD2 with the substrate 5,10-methylenetetrahydropteroylglutamate is 8.5fold higher than its NADP+-dependent activity. While the NAD+-dependent activity of MTHFD2 slightly decreases, its maximal NADP+-dependent activity considerably increases with 5,10-methylenetetrahydropteroylpentaglutamate compared to 5,10-methylenetetrahydropteroylglutamate
-
-
?
5,10-methylenetetrahydropteroylpentaglutamate + NADP+
5,10-methenyltetrahydropteroylpentaglutamate + NADPH + H+
NAD+-dependent dehydrogenase activity of MTHFD2L with the substrate 5,10-methylenetetrahydropteroylglutamate is 3.4fold higher than its NADP+-dependent activity under saturating substrate conditions. While the NAD+-dependent activity of MTHFD2 slightly decreases, its maximal NADP+-dependent activity considerably increases with 5,10-methylenetetrahydropteroylpentaglutamate compared to 5,10-methylenetetrahydropteroylglutamate
-
-
?
additional information
?
-
-
key enzyme in folate metabolism playing a major role in provision of methyl groups for DNA methylation and in production of dTMP for DNA synthesis
-
-
?
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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
L-5,10-methenyl-tetrahydrofolate + NADH
L-5,10-methylenetetrahydrofolate + NAD+
-
-
-
-
r
L-5,10-methylenetetrahydrofolate + NAD+
5,10-methenyl-tetrahydrofolate + NADH
-
-
-
-
r
additional information
?
-
-
key enzyme in folate metabolism playing a major role in provision of methyl groups for DNA methylation and in production of dTMP for DNA synthesis
-
-
?
5,10-methylenetetrahydrofolate + NADP+
5,10-methenyltetrahydrofolate + NADPH + H+
-
-
-
?
5,10-methylenetetrahydrofolate + NADP+
5,10-methenyltetrahydrofolate + NADPH + H+
-
?
-
-
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COFACTOR
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
NAD+
the enzyme exhibits dual redox cofactor specificity, utilizing either NADP+ or NAD+. NAD+-dependent dehydrogenase activity of MTHFD2 with the substrate 5,10-methylenetetrahydropteroylglutamate is 8.5fold higher than its NADP+-dependent activity. While the NAD+-dependent activity of MTHFD2 slightly decreases, its maximal NADP+-dependent activity considerably increases with 5,10-methylenetetrahydropteroylpentaglutamate compared to 5,10-methylenetetrahydropteroylglutamate
NAD+
the enzyme exhibits dual redox cofactor specificity, utilizing either NADP+ or NAD+. NAD+-dependent dehydrogenase activity of MTHFD2L with the substrate 5,10-methylenetetrahydropteroylglutamat is 3.4fold higher than its NADP+-dependent activity under saturating substrate conditions. While the NAD+-dependent activity of MTHFD2 slightly decreases, its maximal NADP+-dependent activity considerably increases with 5,10-methylenetetrahydropteroylpentaglutamate compared to 5,10-methylenetetrahydropteroylglutamate
NADP+
the enzyme exhibits dual redox cofactor specificity, utilizing either NADP+ or NAD+. NAD+-dependent dehydrogenase activity of MTHFD2 with the substrate 5,10-methylenetetrahydropteroylglutamate is 8.5fold higher than its NADP+-dependent activity. While the NAD+-dependent activity of MTHFD2 slightly decreases, its maximal NADP+-dependent activity considerably increases with 5,10-methylenetetrahydropteroylpentaglutamate compared to 5,10-methylenetetrahydropteroylglutamate
NADP+
the enzyme exhibits dual redox cofactor specificity, utilizing either NADP+ or NAD+. NAD+-dependent dehydrogenase activity of MTHFD2L with the substrate 5,10-methylenetetrahydropteroylglutamate is 3.4fold higher than its NADP+-dependent activity under saturating substrate conditions. While the NAD+-dependent activity of MTHFD2 slightly decreases, its maximal NADP+-dependent activity considerably increases with 5,10-methylenetetrahydropteroylpentaglutamate compared to 5,10-methylenetetrahydropteroylglutamate
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METALS and IONS
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
Mg2+
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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
(2S)-2-[[4-[(6aR)-3-amino-1,9-dioxo-5,6,6a,7-tetrahydro-4H-imidazo[1,5-f]pteridin-8-yl]benzoyl]amino]pentanedioic acid
i.e. LY345899
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ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
phosphate
-
absolute requirement, phosphate can be replaced by its analog arsenate
phosphate
absolutely required, binds in close proximity to the 2-hydroxyl of NAD through interactions with R166 and R198. Km-value of wild-type 0.412 mM
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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
3-hydroxyacyl-coa dehydrogenase deficiency
Epidemiology of rare diseases detected by newborn screening in the Czech Republic.
5,10-methylenetetrahydrofolate reductase (fadh2) deficiency
A Novel Homozygous Non-sense Mutation in the Catalytic Domain of MTHFR Causes Severe 5,10-Methylenetetrahydrofolate Reductase Deficiency.
5,10-methylenetetrahydrofolate reductase (fadh2) deficiency
Severe 5,10-methylenetetrahydrofolate reductase deficiency and two MTHFR variants in an adolescent with progressive myoclonic epilepsy.
Abortion, Habitual
Analyzes of three common thrombophilic gene mutations in German women with recurrent abortions.
Abortion, Habitual
Association between the thrombophilic polymorphisms MTHFR C677T, Factor V Leiden, and prothrombin G20210A and recurrent miscarriage in Brazilian women.
Abortion, Habitual
Combined thrombophilic polymorphisms in women with idiopathic recurrent miscarriage.
Abortion, Habitual
Comparison between thrombophilic gene polymorphisms among high risk patients.
Abortion, Habitual
Comparison of two preventive treatments for patients with recurrent miscarriages carrying a C677T methylenetetrahydrofolate reductase mutation: 5-year experience.
Abortion, Habitual
Differential global and MTHFR gene specific methylation patterns in preeclampsia and recurrent miscarriages: A case-control study from North India.
Abortion, Habitual
Evaluation of GenoFlow Thrombophilia Array Test Kit in its detection of mutations in Factor V Leiden (G1691A), prothrombin G20210A, MTHFR C677T and A1298C in blood samples from 113 Turkish female patients.
Abortion, Habitual
Factor V leiden and prothrombin G20210A mutations, but not methylenetetrahydrofolate reductase C677T, are associated with recurrent miscarriages.
Abortion, Habitual
Folic acid and homocyst(e)ine metabolic defects and the risk of placental abruption, pre-eclampsia and spontaneous pregnancy loss: A systematic review.
Abortion, Habitual
Genetic thromobophilia in pregnancy: a case-control study among North Indian women.
Abortion, Habitual
Hyperhomocysteinemia and recurrent early pregnancy loss: a meta-analysis.
Abortion, Habitual
Methylenetetrahydrofolate Reductase C677T and A1298C Polymorphisms in Male Partners of Recurrent Miscarriage Couples.
Abortion, Habitual
Methylenetetrahydrofolate Reductase Gene-specific Methylation and Recurrent Miscarriages: A Case- Control Study from North India.
Abortion, Habitual
Methylenetetrahydrofolate reductase polymorphism affects the change in homocysteine and folate concentrations resulting from low dose folic acid supplementation in women with unexplained recurrent miscarriages.
Abortion, Habitual
Methyltetrahydrofolate vs Folic Acid Supplementation in Idiopathic Recurrent Miscarriage with Respect to Methylenetetrahydrofolate Reductase C677T and A1298C Polymorphisms: A Randomized Controlled Trial.
Abortion, Habitual
MTHFR C677T Polymorphism and Recurrent Early Pregnancy Loss Risk in North Indian Population.
Abortion, Habitual
Plasma homocysteine and vitamin B12 serum levels, red blood cell folate concentrations, C677T methylenetetrahydrofolate reductase gene mutation and risk of recurrent miscarriage: a case-control study in Spain.
Abortion, Habitual
Plasminogen activator inhibitor-1, factor V, factor II and methylenetetrahydrofolate reductase polymorphisms in women with recurrent miscarriage.
Abortion, Habitual
Polymorphisms in MTHFR, MTHFD, and PAI-1 and recurrent miscarriage among North Indian women.
Abortion, Habitual
Pregnancy outcomes in women with epilepsy and MTHFR mutations supplemented with methylated folate and methylcobalamin (methylated B12).
Abortion, Habitual
Prevalent genotypes of methylenetetrahydrofolate reductase (MTHFR) in recurrent miscarriage and recurrent implantation failure.
Abortion, Habitual
Primary habitual abortions are associated with high frequency of factor V Leiden mutation.
Abortion, Habitual
Recurrent abortions in Asian Indians: no role of factor V Leiden Hong Kong/Cambridge mutation and MTHFR polymorphism.
Abortion, Habitual
Statistical Correlations of the Spontaneous Abortion with Trombophilia and Other Associated Pathologies.
Abortion, Habitual
The C677T MTHFR gene mutation is not predictive of risk for recurrent fetal loss.
Abortion, Habitual
The C677T polymorphism of the methylenetetrahydrofolate reductase gene and idiopathic recurrent miscarriage.
Abortion, Habitual
The impact of low molecular weight heparin on obstetric outcomes among unexplained recurrent miscarriages complicated with methylenetetrahydrofolate reductase gene polymorphism.
Abortion, Habitual
The investigation of hereditary and acquired thrombophilia risk factors in the development of complications in pregnancy in Croatian women.
Abortion, Habitual
The role of methylenetetrahydrofolate reductase C677T polymorphism on the peripheral blood natural killer cell proportion in women with unexplained recurrent miscarriages.
Abortion, Habitual
The significance of 1793G>A polymorphism in MTHFR gene in women with first trimester recurrent miscarriages.
Abortion, Habitual
Thrombophilias and recurrent pregnancy loss: a critical appraisal of the literature.
Abortion, Habitual
[Genetic conditioned changes in activity of 5,10-methylenetetrahydrofolate reductase (MTHFR) and recurrent miscarriages]
Abortion, Habitual
[Genetic variant C677T in the MTHFR in women with recurrent early fetal loss]
Abortion, Missed
Maternal methyltetrahydrofolate reductase gene mutation in patients with missed abortions.
Abortion, Spontaneous
Association between gene polymorphism of folate metabolism and recurrent spontaneous abortion in Asia: A Meta-analysis.
Abortion, Spontaneous
Association Between MTHFR 1298A>C Polymorphism and Spontaneous Abortion with Fetal Chromosomal Aneuploidy.
Abortion, Spontaneous
Association of anticardiolipin antibody and C677T in methylenetetrahydrofolate reductase mutation in women with recurrent spontaneous abortions: a new path to thrombophilia?
Abortion, Spontaneous
Association of MTHFR genetic variants C677T and A1298C on predisposition to spontaneous abortion in Slavonic population.
Abortion, Spontaneous
Combined thrombophilic mutations in women with unexplained recurrent miscarriage.
Abortion, Spontaneous
Defect of methylenetetrahydrofolate reductase in a patient with ten habitual misscarriages: a case report.
Abortion, Spontaneous
Effect of methylenetetrahydrofolate reductase and thymidylate synthase enhancer region polymorphisms on the risk of idiopathic recurrent spontaneous abortion in a Korean population.
Abortion, Spontaneous
Evidence of Paternal N5, N10 - Methylenetetrahydrofolate Reductase (MTHFR) C677T Gene Polymorphism in Couples with Recurrent Spontaneous Abortions (RSAs) in Kolar District- A South West of India.
Abortion, Spontaneous
Folic acid and homocyst(e)ine metabolic defects and the risk of placental abruption, pre-eclampsia and spontaneous pregnancy loss: A systematic review.
Abortion, Spontaneous
Gene-environment interactions: a review of effects on reproduction and development.
Abortion, Spontaneous
Gene-gene interaction between fetal MTHFR 677C>T and transcobalamin 776C>G polymorphisms in human spontaneous abortion.
Abortion, Spontaneous
Genetic thrombophilic mutations among couples with recurrent miscarriage.
Abortion, Spontaneous
Has enhanced folate status during pregnancy altered natural selection and possibly Autism prevalence? A closer look at a possible link.
Abortion, Spontaneous
Hyperhomocysteinemia and methylenetetrahydrofolate reductase polymorphism in a patient with coronary artery disease and repetitive miscarriages.
Abortion, Spontaneous
Impaired Placentation and Early Pregnancy Loss in Patients with MTHFR Polymorphisms and Type-1 Diabetes Mellitus.
Abortion, Spontaneous
Influence of combined methylenetetrahydrofolate reductase (MTHFR) and thymidylate synthase enhancer region (TSER) polymorphisms to plasma homocysteine levels in Korean patients with recurrent spontaneous abortion.
Abortion, Spontaneous
Interaction between MTHFR 677C>T, PON1 192Q>R and PON1 55L>M polymorphisms and its effect on non-recurrent spontaneous abortion in Mexican women.
Abortion, Spontaneous
Investigation of the association between C677T polymorphism of the MTHFR gene and plasma homocysteine level in recurrent fetal miscarriage.
Abortion, Spontaneous
Management of hereditary angioedema type I and homozygous MTHFR mutation during pregnancy.
Abortion, Spontaneous
Methylenetetrahydrofolate reductase and transcobalamin genetic polymorphisms in human spontaneous abortion: biological and clinical implications.
Abortion, Spontaneous
Methylenetetrahydrofolate Reductase C677T and A1298C Mutations in Women with Recurrent Spontaneous Abortions in the Northwest of Iran.
Abortion, Spontaneous
Methylenetetrahydrofolate Reductase C677T and A1298C Polymorphisms in Male Partners of Recurrent Miscarriage Couples.
Abortion, Spontaneous
Methylenetetrahydrofolate reductase gene promoter hypermethylation in semen samples of infertile couples correlates with recurrent spontaneous abortion.
Abortion, Spontaneous
Methylenetetrahydrofolate Reductase Polymorphisms and Pregnancy Outcome.
Abortion, Spontaneous
Methylenotetrahydrololate reductase A1298C and C677T polymorphisms and adverse pregnancy outcome in women with PCOS.
Abortion, Spontaneous
Moderately elevated first trimester fasting plasma total homocysteine is associated with increased probability of miscarriage. The Reus-Tarragona Birth Cohort Study.
Abortion, Spontaneous
MTHFR (methylenetetrahydrofolate reductase: EC 1.5.1.20) SNPs (single-nucleotide polymorphisms) and homocysteine in patients referred for investigation of fertility.
Abortion, Spontaneous
MTHFR C677T and A1298C Genotypes and Haplotypes in Slovenian Couples with Unexplained Infertility Problems and in Embryonic Tissues from Spontaneous Abortions.
Abortion, Spontaneous
MTHFR C677T and Factor V Leiden in Recurrent Pregnancy Loss: A Study Among an Endogamous Group in North India.
Abortion, Spontaneous
MTHFR C677T Polymorphism and factor V Leiden mutation are not associated with recurrent spontaneous abortion of unexplained etiology in Japanese women.
Abortion, Spontaneous
MTHFR gene polymorphism and homocysteine levels in spontaneous abortion of pregnant women.
Abortion, Spontaneous
No association of C677T methylenetetrahydrofolate reductase and an endothelial nitric oxide synthase polymorphism with recurrent pregnancy loss.
Abortion, Spontaneous
Plasminogen activator inhibitor 1 4G/5G polymorphism and coagulation factor XIII Val34Leu polymorphism: impaired fibrinolysis and early pregnancy loss.
Abortion, Spontaneous
Polymorphism for mutation of cytosine to thymine at location 677 in the methylenetetrahydrofolate reductase gene is associated with recurrent early fetal loss.
Abortion, Spontaneous
Polymorphisms in the methylene tetrahydrofolate reductase and methionine synthase reductase genes and their correlation with unexplained recurrent spontaneous abortion susceptibility.
Abortion, Spontaneous
Pregnancy outcome in patients with a history of recurrent spontaneous miscarriages and documented thrombophilias.
Abortion, Spontaneous
Prevalence of genetic markers for thrombophilia in recurrent pregnancy loss.
Abortion, Spontaneous
Prospective evaluation of the risk conferred by factor V Leiden and thermolabile methylenetetrahydrofolate reductase polymorphisms in pregnancy.
Abortion, Spontaneous
The 5, 10 methylenetetrahydrofolate reductase C677T mutation and risk of fetal loss: a case series and review of the literature.
Abortion, Spontaneous
The association of parental methylenetetrahydrofolate reductase polymorphisms (MTHFR 677C?>?T and 1298A?>?C) and fetal loss: a case-control study in South Australia.
Abortion, Spontaneous
The importance of folate, vitamins B6 and B12 for the lowering of homocysteine concentrations for patients with recurrent pregnancy loss and MTHFR mutations.
Abortion, Spontaneous
Thrombophilic mutations in Iranian patients with infertility and recurrent spontaneous abortion.
Abortion, Spontaneous
[C677T and A1298C mutation of the methylenetetrahydrofolate reductase gene in unexplained recurrent spontaneous abortion]
Abortion, Spontaneous
[C677T polymorphism of the methylentetrahydrofolate reductase gene as risk factor in women with recurrent abortion]
Abortion, Spontaneous
[Frequencies of C677T and A1298C polymorphisms of methylenetetrahydrofolate reductase gene at the early stage of human individual development]
Abortion, Spontaneous
[Importance of the determination of MTHFR SNPs (Methylene Tetrahydrofolate Reductase Single Nucleotide Polymorphisms) in couple infertility].
Abortion, Spontaneous
[Relationship between three thrombophilic gene mutations and unexplained recurrent early spontaneous abortion]
Abortion, Spontaneous
[Study on the relationship of MTHFR polymorphisms with unexplained recurrent spontaneous abortion]
Abortion, Spontaneous
[The role of 1691G>A (Leiden) mutation in Factor V gene, 20210G>A in prothrombin gene and 677C>T in MTHFR gene in etiology of early pregnancy loss].
Abruptio Placentae
Association of methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism with preterm delivery and placental abruption: a systematic review and meta-analysis.
Abruptio Placentae
Association of MTHFR 677C>T polymorphism with IUGR and placental abruption risk: A systematic review and meta-analysis.
Abruptio Placentae
Association of MTHFR A1298C polymorphism (but not of MTHFR C677T) with elevated homocysteine levels and placental vasculopathies.
Abruptio Placentae
Associations between 2 polymorphisms in the methylenetetrahydrofolate reductase gene and placental abruption.
Abruptio Placentae
Associations between maternal methylenetetrahydrofolate reductase polymorphisms and adverse outcomes of pregnancy: the Hordaland Homocysteine Study.
Abruptio Placentae
Combined heterozygosity for methylenetetrahydrofolate reductase (MTHFR) mutations C677T and A1298C is associated with abruptio placentae but not with intrauterine growth restriction.
Abruptio Placentae
Double inherited thrombophilias and adverse pregnancy outcomes: fashion or science?
Abruptio Placentae
Factor V Leiden, Prothrombin and MTHFR Mutation in Patients with Preeclamsia, Intrauterine Growth Restriction and Placental Abruption.
Abruptio Placentae
Folic acid and homocyst(e)ine metabolic defects and the risk of placental abruption, pre-eclampsia and spontaneous pregnancy loss: A systematic review.
Abruptio Placentae
Inheritance and perinatal consequences of inherited thrombophilia in Greece.
Abruptio Placentae
MTHFD1 R653Q polymorphism is a maternal genetic risk factor for severe abruptio placentae.
Abruptio Placentae
MTHFR C677T polymorphism is not associated with placental abruption or preeclampsia in Finnish women.
Abruptio Placentae
Polymorphisms in various coagulation genes in black South African women with placental abruption.
Abruptio Placentae
The association between maternal methylenetetrahydrofolate reductase C677T and A1298C polymorphism and birth defects and adverse pregnancy outcomes.
Acidosis
Metabolic infrastructure of pregnant women with methylenetetrahydrofolate reductase polymorphisms: A metabolomic analysis.
Acidosis, Lactic
Clinical presentation, etiology, and outcome of stroke in children: A hospital-based study.
Acidosis, Lactic
Inborn Errors of Metabolism Associated With Autism Spectrum Disorders: Approaches to Intervention.
Acromegaly
MTHFR C677T polymorphism, folate status and colon cancer risk in acromegalic patients.
Activated Protein C Resistance
Association between in vitro fertilization outcomes and inherited thrombophilias: a meta-analysis.
Activated Protein C Resistance
Causal relationship of susceptibility genes to ischemic stroke: comparison to ischemic heart disease and biochemical determinants.
Activated Protein C Resistance
Congenital thrombophilia associated to obstetric complications.
Activated Protein C Resistance
Do placental lesions reflect thrombophilia state in women with adverse pregnancy outcome?
Activated Protein C Resistance
Double inherited thrombophilias and adverse pregnancy outcomes: fashion or science?
Activated Protein C Resistance
Factor V1691 G-A, prothrombin 20210 G-A, and methylenetetrahydrofolate reductase 677 C-T variants in Turkish children with cerebral infarct.
Activated Protein C Resistance
How strong is the association between maternal thrombophilia and adverse pregnancy outcome? A systematic review.
Activated Protein C Resistance
Hypercoagulable states in patients with hepatocellular carcinoma.
Activated Protein C Resistance
Hyperhomocysteinemia and other thrombotic risk factors in women with placental vasculopathy.
Activated Protein C Resistance
Increased lipoprotein (a) levels as an independent risk factor for venous thromboembolism.
Activated Protein C Resistance
Lack of association between inherited thrombophilic risk factors and idiopathic sudden sensorineural hearing loss in Italian patients.
Activated Protein C Resistance
Lack of Association between Recurrent Pregnancy Loss and Inherited Thrombophilia in a Group of Colombian Patients.
Activated Protein C Resistance
Left ventricular intracardiac thrombus in a patient with Behçet disease successfully treated with immunosuppressive agents without anticoagulation: a case report and review of the literature.
Activated Protein C Resistance
Prediction of ischemic stroke in young Indians: is thrombophilia profiling a way out?
Activated Protein C Resistance
Primary thrombophilia in Mexico: a single tertiary referral hospital experience.
Activated Protein C Resistance
Profile of prothrombotic factors in Indian children with ischemic stroke.
Activated Protein C Resistance
Recurrent thrombosis in a patient with pseudohomozygous activated protein C resistance and homozygosity for MTHFR gene polymorphism C677T.
Activated Protein C Resistance
Risk factors for thrombophilia in young adults presenting with thrombosis.
Activated Protein C Resistance
Stroke in children: inherited and acquired factors and age-related variations in the presentation of 48 paediatric patients.
Activated Protein C Resistance
The frequency of factor V Leiden and concomitance of factor V Leiden with prothrombin G20210A mutation and methylene tetrahydrofolate reductase C677T gene mutation in healthy population of Denizli, Aegean region of Turkey.
Activated Protein C Resistance
The relationship of the factor V Leiden mutation and pregnancy outcomes for mother and fetus.
Activated Protein C Resistance
Thrombophilia and first arterial ischaemic stroke: a systematic review.
Activated Protein C Resistance
Thrombophilic risk factors in the pathogenesis of non-arteritic anterior ischemic optic neuropathy patients.
Activated Protein C Resistance
Venous thromboembolism, factor V Leiden, and methylenetetrahydrofolate reductase in a sickle cell anemia patient.
Activated Protein C Resistance
[Genetic trombophilia and markers of endotelial activation in patients with preeclampsia]
Acute Coronary Syndrome
Identification of six methylenetetrahydrofolate reductase (MTHFR) genotypes resulting from common polymorphisms: impact on plasma homocysteine levels and development of coronary artery disease.
Acute Coronary Syndrome
Influence of 677 C-->T polymorphism of methylenetetrahydrofolate reductase on medium-term prognosis after acute coronary syndromes.
Acute Coronary Syndrome
MTHFR C677T gene polymorphism and the severity of coronary lesions in acute coronary syndrome.
Acute Coronary Syndrome
Recurrent Myocardial Infarction Despite Normal C-reactive Protein in a Patient with Behcet's Disease and Compound Heterozygous Methylenetetrahydrofolate Reductase (MTHFR) Mutations (C677T and A1298C).
Acute Coronary Syndrome
The role of MTHFR C677T and ALDH2 Glu504Lys polymorphism in acute coronary syndrome in a Hakka population in southern China.
Acute Coronary Syndrome
[Clinical course of acute coronary syndrome in dependence on containing of homozystein and ?677? methylenetetrahydrofolate reductase gene polymorphism].
acyl-coa dehydrogenase deficiency
Epidemiology of rare diseases detected by newborn screening in the Czech Republic.
Adenocarcinoma
A retrospective comparative exploratory study on two Methylentetrahydrofolate Reductase (MTHFR) polymorphisms in esophagogastric cancer: the A1298C MTHFR polymorphism is an independent prognostic factor only in neoadjuvantly treated gastric cancer patients.
Adenocarcinoma
Analysis of relation between C677T genotype in MTHFR gene and prostatic cancer in Iranian males.
Adenocarcinoma
Association of C677T and A1298C MTHFR Polymorphisms and Fluoropyrimidine-induced Toxicity in Mestizo Patients With Metastatic Colorectal Cancer.
Adenocarcinoma
Association of methylenetetrahydrofolate reductase C677T-A1298C polymorphisms with risk for esophageal adenocarcinoma, Barrett's esophagus, and reflux esophagitis.
Adenocarcinoma
C677T and A1298C MTHFR gene polymorphisms and response to fluoropyrimidine-based chemotherapy in Mestizo patients with metastatic colorectal cancer.
Adenocarcinoma
DNA Repair Gene and MTHFR Gene Polymorphisms as Prognostic Markers in Locally Advanced Adenocarcinoma of the Esophagus or Stomach Treated with Cisplatin and 5-Fluorouracil-Based Neoadjuvant Chemotherapy.
Adenocarcinoma
Folate intake, MTHFR polymorphisms, and risk of esophageal, gastric, and pancreatic cancer: a meta-analysis.
Adenocarcinoma
Gene polymorphisms involved in folate and methionine metabolism and increased risk of sporadic colorectal adenocarcinoma.
Adenocarcinoma
Genetic variations in MTHFR and gastric cardia adenocarcinoma susceptibility in the Chinese Han population.
Adenocarcinoma
Impact of thrombophilic gene mutations on thrombosis risk in patients with gastrointestinal carcinoma.
Adenocarcinoma
Methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and susceptibility to gastric adenocarcinoma in an Italian population.
Adenocarcinoma
Methylenetetrahydrofolate reductase C677T polymorphism and risk of adenocarcinoma of the upper gastrointestinal tract.
Adenocarcinoma
Methylenetetrahydrofolate reductase polymorphisms/haplotypes and risk of gastric cancer: a case-control analysis in China.
Adenocarcinoma
Methylenetetrahydrofolate reductase tagging polymorphisms are associated with risk of esophagogastric junction adenocarcinoma: a case-control study involving 2,740 Chinese Han subjects.
Adenocarcinoma
MTHFR C677T polymorphism in chronic pancreatitis and pancreatic adenocarcinoma.
Adenocarcinoma
Polymorphisms in methylenetetrahydrofolate reductase gene (MTHFR) and the age of onset of sporadic colorectal adenocarcinoma.
Adenocarcinoma
Polymorphisms of MTHFR and susceptibility to oesophageal adenocarcinoma in a Caucasian United Kingdom population.
Adenocarcinoma
Susceptibility to gastric cardia adenocarcinoma and genetic polymorphisms in methylenetetrahydrofolate reductase in an at-risk Chinese population.
Adenocarcinoma
The methylenetetrahydrofolate reductase C677T mutation induces cell-specific changes in genomic DNA methylation and uracil misincorporation: a possible molecular basis for the site-specific cancer risk modification.
Adenocarcinoma
[Prediction of response to neoadjuvant chemotherapy in Barrett's carcinoma by quantitative gene expression analysis]
Adenocarcinoma
[Single nucleotide polymorphisms in methylenetetrahydrofolate reductase gene and susceptibility to cancer of the gastric cardia in Chinese population]
Adenocarcinoma of Lung
Meta-analysis on MTHFR polymorphism and lung cancer susceptibility in East Asian populations.
Adenocarcinoma of Lung
MTHFR C677T and A1298C polymorphisms and lung cancer risk in a female Chinese population.
Adenocarcinoma of Lung
The influence of methylenetetrahydrofolate reductase and thymidylate synthetase gene polymorphisms on lung adenocarcinoma occurrence.
Adenoma
A prospective study of methylenetetrahydrofolate reductase and methionine synthase gene polymorphisms, and risk of colorectal adenoma.
Adenoma
Colorectal adenomas and the C677T MTHFR polymorphism: evidence for gene-environment interaction?
Adenoma
Dietary factors and biomarkers involved in the methylenetetrahydrofolate reductase genotype-colorectal adenoma pathway.
Adenoma
Dietary folate intake in combination with MTHFR C677T genotype and promoter methylation of tumor suppressor and DNA repair genes in sporadic colorectal adenomas.
Adenoma
Dietary intake of folate and riboflavin, MTHFR C677T genotype, and colorectal adenoma risk: a Dutch case-control study.
Adenoma
Different roles of MTHFR C677T and A1298C polymorphisms in colorectal adenoma and colorectal cancer: a meta-analysis.
Adenoma
Folate intake, MTHFR C677T polymorphism, alcohol consumption, and risk for sporadic colorectal adenoma (United States).
Adenoma
Folic acid and vitamin B-12 supplementation does not favorably influence uracil incorporation and promoter methylation in rectal mucosa DNA of subjects with previous colorectal adenomas.
Adenoma
Genetic and epigenetic variation in the DNMT3B and MTHFR genes and colorectal adenoma risk.
Adenoma
Genetic polymorphisms of methylenetetrahydrofolate reductase and aldehyde dehydrogenase 2, alcohol use and risk of colorectal adenomas: Self-Defense Forces Health Study.
Adenoma
Genetic polymorphisms of methylenetetrahydrofolate reductase and colorectal cancer and adenoma.
Adenoma
Lack of Influence of the ADH1B Arg47His Genetic Polymorphism on Risk of Colorectal Adenoma in Middle-aged Japanese Men.
Adenoma
Low folate status, and MTHFR 677C?>?T and MTR 2756A?>?G polymorphisms associated with colorectal cancer risk in Thais: a case-control study.
Adenoma
Methylene tetrahydrofolate reductase genotype modifies the chemopreventive effect of folate in colorectal adenoma, but not colorectal cancer.
Adenoma
Methylenetetrahydrofolate reductase deficiency and low dietary folate reduce tumorigenesis in Apc min/+ mice.
Adenoma
Methylenetetrahydrofolate reductase, alcohol dehydrogenase, diet, and risk of colorectal adenomas.
Adenoma
MTHFR (C677T and A1298C) polymorphisms and risk of sporadic distal colorectal adenoma in the UK Flexible Sigmoidoscopy Screening Trial (United Kingdom).
Adenoma
MTHFR genotype and colorectal adenoma recurrence: data from a double-blind placebo-controlled clinical trial.
Adenoma
MTHFR polymorphism, methyl-replete diets and the risk of colorectal carcinoma and adenoma among U.S. men and women: an example of gene-environment interactions in colorectal tumorigenesis.
Adenoma
Quantification of gene-specific methylation of DNMT3B and MTHFR using sequenom EpiTYPER®.
Adenoma
Relation of plasma folate and methylenetetrahydrofolate reductase C677T polymorphism to colorectal adenomas.
Adenoma
Smoking, folate and methylenetetrahydrofolate reductase status as interactive determinants of adenomatous and hyperplastic polyps of colorectum.
Adenoma
The methylenetetrahydrofolate reductase 677C-->T polymorphism and distal colorectal adenoma risk.
Adenoma
Vitamins B2, B6, and B12 and risk of new colorectal adenomas in a randomized trial of aspirin use and folic acid supplementation.
Adenoma
[677T mutation of the MTHFR gene in adenomas and colorectal cancer in a population sample from the Northeastern Mexico. Preliminary results]
Adenomatous Polyposis Coli
Folate status and risk of colorectal polyps in African Americans.
Adenomatous Polyps
MTHFR (C677T and A1298C) polymorphisms and risk of sporadic distal colorectal adenoma in the UK Flexible Sigmoidoscopy Screening Trial (United Kingdom).
Adenomatous Polyps
Polymorphisms in genes involved in folate metabolism and colorectal neoplasia: a HuGE review.
adenosylhomocysteinase deficiency
Inborn Errors of Metabolism Associated With Autism Spectrum Disorders: Approaches to Intervention.
Adrenal Hyperplasia, Congenital
Epidemiology of rare diseases detected by newborn screening in the Czech Republic.
Adrenoleukodystrophy
Genetic variants of methionine metabolism and X-ALD phenotype generation: results of a new study sample.
Alagille Syndrome
Agenesis of the internal carotid artery: associated malformations including a high rate of aortic and cardiac malformations.
Albuminuria
Hyperhomocysteinemia is independently associated with albuminuria in the population-based CoLaus study.
Albuminuria
Interrelation of cardiovascular risk factors with high albuminury among patients with arterial hypertension living in Mountain Shoriya.
Albuminuria
MTHFR C677T, A1298C and ACE I/D polymorphisms as risk factors for diabetic nephropathy among type 2 diabetic patients.
Albuminuria
Mutation C677T of methylenetetrahydrofolate reductase gene is not associated with coronary artery disease, but possibly with albuminuria, in type 2 diabetic patients.
Alcohol Withdrawal Seizures
Methylenetetrahydrofolate reductase C677T-polymorphism and its association with alcohol withdrawal seizure.
Alopecia
Methotrexate (MTX) pathway gene polymorphisms and their effects on MTX toxicity in Caucasian and African American patients with rheumatoid arthritis.
Alopecia
MTHFR C677T Polymorphism and Serum Homocysteine Level as Risk Factors of Coronary Heart Disease in Patients with Androgenetic Alopecia: A Case Control Study.
Alopecia Areata
Methylenetetrahydrofolate reductase C677T mutation in patients with alopecia areata in Turkish population.
alpha-Thalassemia
The clinical impact of MTHFR polymorphism on the vascular complications of sickle cell disease.
Alzheimer Disease
A haplotype of the methylenetetrahydrofolate reductase gene is protective against late-onset Alzheimer's disease.
Alzheimer Disease
Allelic Distribution of Genes for Apolipoprotein E and MTHFR in Patients with Alzheimer's Disease and Their Epistatic Interaction.
Alzheimer Disease
Alzheimer's disease in Brazilian elderly has a relation with homocysteine but not with MTHFR polymorphisms.
Alzheimer Disease
Apolipoprotein E, methylenetetrahydrofolate reductase (MTHFR) mutation and the risk of senile dementia--an epidemiological study using the polymerase chain reaction (PCR) method.
Alzheimer Disease
Association Between the MTHFR Gene and Alzheimer's Disease: A Meta-Analysis.
Alzheimer Disease
Association of IL-1 RN*2 allele and methionine synthase 2756 AA genotype with dementia severity of sporadic Alzheimer's disease.
Alzheimer Disease
Association of methylenetetrahydrofolate reductase polymorphisms with susceptibility to Alzheimer's disease.
Alzheimer Disease
Association of MTHFR gene polymorphism C677T with susceptibility to late-onset Alzheimer's disease.
Alzheimer Disease
Association of RFC1 A80G and MTHFR C677T polymorphisms with Alzheimer's disease.
Alzheimer Disease
Common polymorphisms in methylenetetrahydrofolate reductase (MTHFR): relationships with plasma homocysteine concentrations and cognitive status in elderly northern italian subjects.
Alzheimer Disease
Early Manifestations of Brain Aging in Mice Due to Low Dietary Folate and Mild MTHFR Deficiency.
Alzheimer Disease
Epigenetic Factors in Late-Onset Alzheimer's Disease: MTHFR and CTH Gene Polymorphisms, Metabolic Transsulfuration and Methylation Pathways, and B Vitamins.
Alzheimer Disease
Folate Pathway Gene Methylenetetrahydrofolate Reductase C677T Polymorphism and Alzheimer Disease Risk in Asian Population.
Alzheimer Disease
Folate, Homocysteine, Vitamin B12, and Polymorphisms of Genes Participating in One-Carbon Metabolism in Late-Onset Alzheimer's Disease Patients and Healthy Controls.
Alzheimer Disease
Frequency of APOE, MTHFR and ACE polymorphisms in the Zambian population.
Alzheimer Disease
Genetic effect of MTHFR C677T polymorphism on the structural covariance network and white-matter integrity in Alzheimer's disease.
Alzheimer Disease
Genetic effect of MTHFR C677T, A1298C, and A1793G polymorphisms on the age at onset, plasma homocysteine, and white matter lesions in Alzheimer's disease in the Chinese population.
Alzheimer Disease
Genetic polymorphisms in older subjects with vascular or Alzheimer's dementia.
Alzheimer Disease
Homocysteine and methylenetetrahydrofolate reductase polymorphism in Alzheimer's disease.
Alzheimer Disease
Homocysteine, apolipoproteine E and methylenetetrahydrofolate reductase in Alzheimer's disease and mild cognitive impairment.
Alzheimer Disease
Hyperhomocysteinemia and homozygous MTHFR 677C>T mutation finding in an Alzheimer's disease case with metabolic syndrome diagnosis.
Alzheimer Disease
Interaction between interleukin-8 and methylenetetrahydrofolate reductase genes modulates Alzheimer's disease risk.
Alzheimer Disease
Lack of association between MTHFR A1298C variant and Alzheimer's disease: evidence from a systematic review and cumulative meta-analysis.
Alzheimer Disease
Meta-analysis of the methylenetetrahydrofolate reductase C677T polymorphism and susceptibility to Alzheimer's disease.
Alzheimer Disease
Meta-Prediction of the Effect of Methylenetetrahydrofolate Reductase Polymorphisms and Air Pollution on Alzheimer's Disease Risk.
Alzheimer Disease
Methylenetetrahydrofolate reductase (MTHFR) C667T polymorphism and susceptibility to late-onset Alzheimer's disease in the Italian population. A systematic review and meta-analysis.
Alzheimer Disease
Methylenetetrahydrofolate Reductase (MTHFR) C677T Polymorphism and Alzheimer Disease Risk: a Meta-Analysis.
Alzheimer Disease
Methylenetetrahydrofolate reductase and angiotensin converting enzyme gene polymorphisms in two genetically and diagnostically distinct cohort of Alzheimer patients.
Alzheimer Disease
Methylenetetrahydrofolate reductase gene and risk of Alzheimer's disease in Koreans.
Alzheimer Disease
Moderately elevated plasma homocysteine, methylenetetrahydrofolate reductase genotype, and risk for stroke, vascular dementia, and Alzheimer disease in Northern Ireland.
Alzheimer Disease
MTHFR Gene Mutations: A Potential Marker of Late-Onset Alzheimer's Disease?
Alzheimer Disease
Relationship between genetic polymorphism, serum folate and homocysteine in Alzheimer's disease.
Alzheimer Disease
Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database.
Alzheimer Disease
The C677T methylenetetrahydrofolate reductase mutation is not associated with Alzheimer's disease.
Alzheimer Disease
The C677T mutation in the methylenetetrahydrofolate reductase (MTHFR) gene and vascular dementia.
Alzheimer Disease
The C677T Polymorphism of the Methylenetetrahydrofolate Reductase Gene and Susceptibility to Late-onset Alzheimer's Disease.
Alzheimer Disease
The Methylenetetrahydrofolate Reductase C677T Polymorphism and Risk for Late-Onset Alzheimer's disease: Further Evidence in an Italian Multicenter Study.
Alzheimer Disease
The MTHFR 677T allele may influence the severity and biochemical risk factors of Alzheimer's disease in an Egyptian population.
Alzheimer Disease
The MTHFR C677T polymorphism contributes to increased risk of Alzheimer's disease: evidence based on 40 case-control studies.
Alzheimer Disease
The regulatory region polymorphisms of the MTHFR gene are not associated with Alzheimer's disease.
Alzheimer Disease
The sex-specific effect of the apolipoprotein E allele and methylenetetrahydrofolate reductase gene polymorphism on the biochemical, anatomical, and cognitive profiles of patients clinically diagnosed with probable Alzheimer's disease.
Alzheimer Disease
[Alzheimer's disease and methylenetetrahydrofolate reductase gene polymorphisms: a potential nutrigenomic approach for Mexico]
Amyotrophic Lateral Sclerosis
Association between C677T polymorphism of MTHFR gene and risk of amyotrophic lateral sclerosis: Polish population study and a meta-analysis.
Amyotrophic Lateral Sclerosis
Gender-Specific Association of Methylenetetrahydrofolate Reductase Gene Polymorphisms with Sporadic Amyotrophic Lateral Sclerosis.
Amyotrophic Lateral Sclerosis
MTHFR C677T allelic variant is not associated with plasma and cerebrospinal fluid homocysteine in amyotrophic lateral sclerosis.
Anemia
A C677T methylenetetrahydrofolate reductase (MTHFR) polymorphism and G20210A mutation in the prothrombin gene of sickle cell anemia patients from Northeast Brazil.
Anemia
Association of C677T and A1298C MTHFR Polymorphisms and Fluoropyrimidine-induced Toxicity in Mestizo Patients With Metastatic Colorectal Cancer.
Anemia
Gene polymorphisms in folate metabolizing enzymes in adult acute lymphoblastic leukemia: effects on methotrexate-related toxicity and survival.
Anemia
Gene-Gene Interactions of Gemcitabine Metabolizing-Enzyme Genes hCNT3 and WEE1 for Preventing Severe Gemcitabine-Induced Hematological Toxicity.
Anemia
High dose methotrexate treatment in childhood ALL: pilot study on the impact of the MTHFR 677C>T and 1298A>C polymorphisms on MTX-related toxicity.
Anemia
Methylene tetrahydrofolate reductase gene mutation in sickle cell anaemia patients in Lagos, Nigeria.
Anemia
Methylenetetrahydrofolate reductase C677T and A1298C gene polymorphisms and therapy-related toxicity in children treated for acute lymphoblastic leukemia and non-Hodgkin lymphoma.
Anemia
MTHFR polymorphisms involved in vitamin B12 deficiency associated with atrophic gastritis.
Anemia
The Methylenetetrahydrofolate Reductase C677T (rs1801133) and Apolipoprotein A5-1131T>C (rs662799) Polymorphisms, and Anemia Are Independent Risk Factors for Ischemic Stroke.
Anemia
Venous thromboembolism, factor V Leiden, and methylenetetrahydrofolate reductase in a sickle cell anemia patient.
Anemia, Diamond-Blackfan
A child with Diamond-Blackfan anemia, methylenetetrahydrofolate reductase mutation, and perinatal stroke.
Anemia, Hemolytic
Hemolysis and hyperhomocysteinemia caused by cobalamin deficiency: three case reports and review of the literature.
Anemia, Iron-Deficiency
Homozygous MTHFR C677T gene mutation and recurrent stroke in an infant.
Anemia, Megaloblastic
Acute leukoencephalopathy possibly induced by phenytoin intoxication in an adult patient with methylenetetrahydrofolate reductase deficiency.
Anemia, Megaloblastic
Hyperhomocysteinemia, deep vein thrombosis and vitamin B12 deficiency in a metformin-treated diabetic patient.
Anemia, Pernicious
[Portal and mesenteric vein thrombosis associated with hyperhomocysteinemia and pernicious anemia in a patient heterozygous for the MTHFR C677T mutation.]
Anemia, Sickle Cell
A C677T methylenetetrahydrofolate reductase (MTHFR) polymorphism and G20210A mutation in the prothrombin gene of sickle cell anemia patients from Northeast Brazil.
Anemia, Sickle Cell
Association between MTHFR 677C>T polymorphism and vascular complications in sickle cell disease: A meta-analysis.
Anemia, Sickle Cell
Association of the Methylenetetrahydrofolate Reductase A1298C but not the C677T Single Nucleotide Polymorphism with Sickle Cell Disease in Bahrain.
Anemia, Sickle Cell
Clinical impact of factor V Leiden, prothrombin G20210A, and MTHFR C677T mutations among sickle cell disease patients of Central India.
Anemia, Sickle Cell
Correlation of the C677T MTHFR genotype with homocysteine levels in children with sickle cell disease.
Anemia, Sickle Cell
Factor V Leiden G1691A, Prothrombin G20210A, and MTHFR C677T and A1298C Mutations in Patients With Sickle Cell Disease in Tunisia.
Anemia, Sickle Cell
Factor V-Leiden, prothrombin G20210A, and MTHFR C677T mutations among patients with sickle cell disease in Eastern Saudi Arabia.
Anemia, Sickle Cell
Frequency of the 677 C-->T mutation of the methylenetetrahydrofolate reductase gene among Kuwaiti sickle cell disease patients.
Anemia, Sickle Cell
Frequency of the MTHFR C677T polymorphism in Yemeni children with sickle cell disease.
Anemia, Sickle Cell
Methylene tetrahydrofolate reductase gene mutation in sickle cell anaemia patients in Lagos, Nigeria.
Anemia, Sickle Cell
Methylenetetrahydrofolate reductase polymorphisms as genetic markers to predict homocysteinemia and clinical severity in sickle cell disease.
Anemia, Sickle Cell
Prothrombin mutant, factor V Leiden, and thermolabile variant of methylenetetrahydrofolate reductase among patients with sickle cell disease in Brazil.
Anemia, Sickle Cell
The 844ins68 cystathionine beta-synthase and C677T MTHFR gene polymorphism and the vaso-occlusive event risk in sickle cell disease.
Anemia, Sickle Cell
The clinical impact of MTHFR polymorphism on the vascular complications of sickle cell disease.
Anemia, Sickle Cell
The methylene tetrahydrofolate reductase (C677T) mutation as a potential risk factor for avascular necrosis in sickle cell disease.
Anemia, Sickle Cell
The methylenetetrahydrofolate reductase gene C677T mutant and ischemic stroke in sickle cell disease.
Anemia, Sickle Cell
The methylenetetrahydrofolate reductase gene C677T polymorphism in patients with homozygous sickle cell disease and stroke.
Anemia, Sickle Cell
The Prevalence of Factor V Leiden (G1691A) and Methylenetetrahydrofolate Reductase C677T Mutations in Sickle Cell Disease in Western India.
Anemia, Sickle Cell
Venous thromboembolism, factor V Leiden, and methylenetetrahydrofolate reductase in a sickle cell anemia patient.
Anencephaly
5,10 Methylenetetrahydrofolate reductase genetic polymorphism as a risk factor for neural tube defects.
Anencephaly
Amniotic fluid homocysteine levels, 5,10-methylenetetrahydrafolate reductase genotypes, and neural tube closure sites.
Anencephaly
Effect on risk of anencephaly of gene-nutrient interactions between methylenetetrahydrofolate reductase C677T polymorphism and maternal folate, vitamin B12 and homocysteine profile.
Anencephaly
Methylenetetrahydrofolate reductase gene polymorphisms and the risk of anencephaly in Mexico.
Anencephaly
Variants in maternal COMT and MTHFR genes and risk of neural tube defects in offspring.
Aneurysm
Brachial artery aneurysm accompanying a homozygous methylenetetrahydrofolate reductase mutation.
Aneurysm
Methylation map genes can be critical in determining the methylome of intracranial aneurysm patients.
Aneurysm
Relationship of genetic factors with development of aortic dissection and aneurysm.
Aneurysm, Dissecting
Relationship of genetic factors with development of aortic dissection and aneurysm.
Angelman Syndrome
Methylenetetrahydrofolate reductase deficiency in a patient with phenotypic findings of Angelman syndrome.
Angioedemas, Hereditary
Hereditary angioedema type III, recurrent pregnancy loss and heterozygous MTHFR mutation.
Angioedemas, Hereditary
Management of hereditary angioedema type I and homozygous MTHFR mutation during pregnancy.
Angioedemas, Hereditary
Successful management of hereditary angioedema during pregnancy in a patient with heterozygous MTHFR mutation.
Anorectal Malformations
No major role for periconceptional folic acid use and its interaction with the MTHFR C677T polymorphism in the etiology of congenital anorectal malformations.
Antiphospholipid Syndrome
Acute adrenal failure associated with primary antiphospholipid syndrome and homozygosity for MTHFR C677T.
Antiphospholipid Syndrome
Case report: Acute myocardial infarction in a 32-year-old white male found to have antiphospholipid antibody syndrome and MTHFR mutation homozygosity.
Antiphospholipid Syndrome
Co-existence of renovascular hypertension, polyarteritis nodosa, antiphospholipid syndrome and methylenetetrahydrofolate reductase mutation.
Antiphospholipid Syndrome
Evaluation of cerebral venous thrombosis secondary to oral contraceptive use in adolescents.
Antiphospholipid Syndrome
Impact of plasma homocysteine and prothrombin G20210 A on primary antiphospholipid syndrome.
Antiphospholipid Syndrome
Recurrent miscarriage syndrome and infertility due to blood coagulation protein/platelet defects: a review and update.
Antiphospholipid Syndrome
Review article: the aetiology of primary Budd-Chiari syndrome - differences between the West and China.
Antiphospholipid Syndrome
Statistical Correlations of the Spontaneous Abortion with Trombophilia and Other Associated Pathologies.
Antiphospholipid Syndrome
The impact of the search for thrombophilia risk factors among antiphospholipid syndrome patients with thrombosis.
Antiphospholipid Syndrome
[Cerebral venous thrombosis: when etiology makes the difference.]
Antiphospholipid Syndrome
[FETAL LOSSES DURING THE MATURATION OF THE PLACENTA AND THE RELATIONSHIP WITH SOME PROCOAGULANT CONDITIONS.]
Antiphospholipid Syndrome
[Prevalence of thrombophilic conditions and genetic carrier status in neuroischaemic form of diabetic foot].
Antiphospholipid Syndrome
[Prognostic value of allelic variants affecting the hemostatic system in the development of antiphospholipid syndrome and kidney lesion in patients with systemic lupus erythematosus].
Antithrombin III Deficiency
Adverse pregnancy outcomes are associated with multiple maternal thrombophilic factors.
Antithrombin III Deficiency
Etiology of hypercoagulable state in women with recurrent fetal loss without other causes of miscarriage from Southern Italy: new clinical target for antithrombotic therapy.
Antithrombin III Deficiency
Evaluation of cerebral venous thrombosis secondary to oral contraceptive use in adolescents.
Antithrombin III Deficiency
Inherited and acquired thrombophilias and poor pregnancy outcome: should we be treating with heparin?
Antithrombin III Deficiency
Inherited prothrombotic defects in Budd-Chiari syndrome and portal vein thrombosis: a study from North India.
Antithrombin III Deficiency
Ischemic stroke subtypes and thrombophilia in young and elderly Brazilian stroke patients admitted to a rehabilitation hospital.
Antithrombin III Deficiency
Outcome after kidney transplantation in children with thrombotic risk factors.
Antithrombin III Deficiency
Review of Management and Outcomes in Women with Thrombophilia Risk during Pregnancy at a Single Institution.
Antithrombin III Deficiency
Risk factors for thrombophilia in young adults presenting with thrombosis.
Antithrombin III Deficiency
The relationship of the factor V Leiden mutation and pregnancy outcomes for mother and fetus.
Antithrombin III Deficiency
Thrombophilia in young patients with acute myocardial infarction.
Antithrombin III Deficiency
Thrombophilia is common in women with idiopathic pregnancy loss and is associated with late pregnancy wastage.
Antithrombin III Deficiency
Thrombophilia is significantly associated with severe preeclampsia: results of a large-scale, case-controlled study.
Antithrombin III Deficiency
[Acquired and inherited hypercoagulability among patients with cerebral venous thrombosis]
Aortic Aneurysm
Hyperhomocysteinemia during aortic aneurysm, a plausible role of epigenetics.
Aortic Aneurysm, Abdominal
Association between MTHFR C677T polymorphism and abdominal aortic aneurysm risk: A comprehensive meta-analysis with 10,123 participants involved.
Aortic Aneurysm, Abdominal
Hyperhomocysteinaemia is an independent risk factor of abdominal aortic aneurysm in a Chinese Han population.
Aortic Aneurysm, Abdominal
Hyperhomocysteinaemia, low folate concentrations and MTHFR C677T mutation in abdominal aortic aneurysm.
Aortic Aneurysm, Abdominal
Increased risk of the abdominal aortic aneurysm in carriers of the MTHFR 677T allele.
Aortic Aneurysm, Abdominal
Methylenetetrahydrofolate reductase mutation in subjects with abdominal aortic aneurysm subdivided for age.
Aortic Aneurysm, Abdominal
Plasma total homocysteine is associated with abdominal aortic aneurysm and aortic diameter in older men.
Aortic Aneurysm, Abdominal
The methylenetetrahydrofolate reductase C677T polymorphism does not associate with susceptibility to abdominal aortic aneurysm.
Aortic Aneurysm, Abdominal
[The different genotypes of MTHFR 1298A>C and PON1 -108C>T polymorphisms confer the increased risk of the abdominal aortic aneurysm in the smoking and nonsmoking persons]
Aortic Aneurysm, Abdominal
[The normotensive carriers of the MTHFR 677T allele, displaying the increased risk of development of the abdominal aortic aneurysm (AAA), occur at the highest frequency among the smoking patients]
Aortic Aneurysm, Thoracic
First genetic analysis of aneurysm genes in familial and sporadic abdominal aortic aneurysm.
Aortic Valve Stenosis
Risk of congenital heart defects is influenced by genetic variation in folate metabolism.
Aphasia
Ischemic Stroke in a Patient With Atrial Tachycardia, Methylenetetrahydrofolate Reductase Mutation and New-Onset Atrial Fibrillation: Is Early Initiation of Anticoagulation Therapy Indicated?
aromatic-l-amino-acid decarboxylase deficiency
Targeted cerebrospinal fluid analysis for inborn errors of metabolism on an LC-MS/MS analysis platform.
Arsenic Poisoning
Increased neurotoxicity of arsenic in methylenetetrahydrofolate reductase deficiency.
Arsenic Poisoning
[Study on the relationship between methylenetetra-hydrofolatereductase gene (677C-->T) mutation and skin lesions in endemic arsenic poisoning]
Arterial Occlusive Diseases
C677T substitution in the methylenetetrahydrofolate reductase gene as a risk factor for venous thrombosis and arterial disease in selected patients.
Arterial Occlusive Diseases
Contribution of the cystathionine beta-synthase gene (844ins68) polymorphism to the risk of early-onset venous and arterial occlusive disease and of fasting hyperhomocysteinemia.
Arterial Occlusive Diseases
Polymorphism in the methylenetetrahydrofolate reductase (C677T) gene and homocysteine levels: a comparison in Brazilian patients with coronary arterial disease, ischemic stroke and peripheral arterial obstructive disease.
Arteriosclerosis
Association of plasma homocysteine with serum interleukin-6 and C-peptide levels in patients with type 2 diabetes.
Arteriosclerosis
The model homologue of the partially defective human 5,10-methylenetetrahydrofolate reductase, considered as a risk factor for stroke due to increased homocysteine level, can be protected and reactivated by heat shock proteins.
Arteriovenous Fistula
Are homocysteine and MTHFR genotype polymorphism associated with arteriovenous fistula patency?
Arteriovenous Fistula
The methylentetrahydrofolate reductase C677T point mutation is a risk factor for vascular access thrombosis in hemodialysis patients.
Arteriovenous Malformations
The incidence of severe intraventricular hemorrhage based on retrospective analysis of 35939 full-term newborns-report of two cases and review of literature.
Arthritis
677TT genotype is associated with elevated risk of methotrexate (MTX) toxicity in juvenile idiopathic arthritis: treatment outcome, erythrocyte concentrations of MTX and folates, and MTHFR polymorphisms.
Arthritis
Cardiovascular events are not associated with MTHFR polymorphisms, but are associated with methotrexate use and traditional risk factors in US veterans with rheumatoid arthritis.
Arthritis
Complete clinical and functional recovery following low-dose methotrexate related paraparesis in a patient with compound c.1298A>C AND c.677C>T MTHFR polymorphism: A case report.
Arthritis
Influence of methylenetetrahydrofolate reductase polymorphisms on efficacy and toxicity of methotrexate in patients with juvenile idiopathic arthritis.
Arthritis
Mutations in the MTHFR gene are not associated with Methotrexate intolerance in patients with juvenile idiopathic arthritis.
Arthritis, Juvenile
677TT genotype is associated with elevated risk of methotrexate (MTX) toxicity in juvenile idiopathic arthritis: treatment outcome, erythrocyte concentrations of MTX and folates, and MTHFR polymorphisms.
Arthritis, Juvenile
Influence of methylenetetrahydrofolate reductase polymorphisms on efficacy and toxicity of methotrexate in patients with juvenile idiopathic arthritis.
Arthritis, Juvenile
Mutations in the MTHFR gene are not associated with Methotrexate intolerance in patients with juvenile idiopathic arthritis.
Arthritis, Rheumatoid
677C > T and 1298A > C MTHFR polymorphisms affect arechin treatment outcome in rheumatoid arthritis.
Arthritis, Rheumatoid
677C>T and 1298A>C MTHFR polymorphisms affect methotrexate treatment outcome in rheumatoid arthritis.
Arthritis, Rheumatoid
A novel single nucleotide polymorphism of the human methylenetetrahydrofolate reductase gene in Japanese individuals.
Arthritis, Rheumatoid
A1298C polymorphism in the MTHFR gene predisposes to cardiovascular risk in rheumatoid arthritis.
Arthritis, Rheumatoid
Anti-tumour necrosis factor-alpha response associated with combined CD226 and HLA-DRB1[*]0404 haplotype in rheumatoid arthritis.
Arthritis, Rheumatoid
Association Between MTHFR C677T Polymorphism and Methotrexate Treatment Outcome in Rheumatoid Arthritis Patients: A Systematic Review and Meta-Analysis.
Arthritis, Rheumatoid
Association of hyperhomocysteinemia with genetic variants in key enzymes of homocysteine metabolism and methotrexate toxicity in rheumatoid arthritis patients.
Arthritis, Rheumatoid
Association of MTHFR and RFC1 gene polymorphisms with methotrexate efficacy and toxicity in Chinese Han patients with rheumatoid arthritis.
Arthritis, Rheumatoid
Association of MTHFR C677T and A1298C gene polymorphisms with methotrexate efficiency and toxicity in Algerian rheumatoid arthritis patients.
Arthritis, Rheumatoid
Association of the MTHFR C677T and A1298C polymorphisms with methotrexate toxicity in rheumatoid arthritis: a meta-analysis.
Arthritis, Rheumatoid
Associations between asymmetric dimethylarginine, homocysteine, and the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism (rs1801133) in rheumatoid arthritis.
Arthritis, Rheumatoid
Associations between C677T and A1298C polymorphisms of MTHFR and susceptibility to rheumatoid arthritis: a systematic review and meta-analysis.
Arthritis, Rheumatoid
Associations between methotrexate treatment and methylenetetrahydrofolate reductase gene polymorphisms with incident fractures in Japanese female rheumatoid arthritis patients.
Arthritis, Rheumatoid
Associations between single-nucleotide polymorphisms of RFC-1, GGH, MTHFR, TYMS and TCII and the efficacy and toxicity of methotrexate treatment in patients with rheumatoid arthritis.
Arthritis, Rheumatoid
Associations between the C677T and A1298C polymorphisms of MTHFR and the efficacy and toxicity of methotrexate in rheumatoid arthritis: a meta-analysis.
Arthritis, Rheumatoid
Associations between the genetic polymorphisms of MTHFR and outcomes of methotrexate treatment in rheumatoid arthritis.
Arthritis, Rheumatoid
Associations of methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms with genetic susceptibility to rheumatoid arthritis: a meta-analysis.
Arthritis, Rheumatoid
Cardiovascular events are not associated with MTHFR polymorphisms, but are associated with methotrexate use and traditional risk factors in US veterans with rheumatoid arthritis.
Arthritis, Rheumatoid
Contribution of MTHFR gene variants in lupus related subclinical atherosclerosis.
Arthritis, Rheumatoid
Cost-effectiveness analysis of MTHFR polymorphism screening by polymerase chain reaction in Korean patients with rheumatoid arthritis receiving methotrexate.
Arthritis, Rheumatoid
Detection of six single-nucleotide polymorphisms associated with rheumatoid arthritis by a loop-mediated isothermal amplification method and an electrochemical DNA chip.
Arthritis, Rheumatoid
Differing effects of methylenetetrahydrofolate reductase single nucleotide polymorphisms on methotrexate efficacy and toxicity in rheumatoid arthritis.
Arthritis, Rheumatoid
Effect of MTHFR, TGF?1, and TNFB polymorphisms on osteoporosis in rheumatoid arthritis patients.
Arthritis, Rheumatoid
Genetic Polymorphisms of TYMS, MTHFR, ATIC, MTR, and MTRR Are Related to the Outcome of Methotrexate Therapy for Rheumatoid Arthritis in a Chinese Population.
Arthritis, Rheumatoid
High-resolution melting curve analysis for genotyping of common SNP in MTHFR gene using fixed-cell suspension.
Arthritis, Rheumatoid
Homocysteine and folate status in methotrexate-treated patients with rheumatoid arthritis.
Arthritis, Rheumatoid
IL-4 and MTHFR gene polymorphism in rheumatoid arthritis and their effects.
Arthritis, Rheumatoid
Impact of MTHFR rs1801133, MTHFR rs1801131 and ABCB1 rs1045642 polymorphisms with increased susceptibility of rheumatoid arthritis in the West Algerian population: A case-control study.
Arthritis, Rheumatoid
Influence of MTHFR C677T gene polymorphism in the development of cardiovascular disease in Egyptian patients with rheumatoid arthritis.
Arthritis, Rheumatoid
Influence of MTHFR C677T polymorphism on methotrexate monotherapy discontinuation in rheumatoid arthritis patients: results from the GAPAID European project.
Arthritis, Rheumatoid
Lack of association between MTHFR A1298C polymorphism and outcome of methotrexate treatment in rheumatoid arthritis patients: evidence from a systematic review and meta-analysis.
Arthritis, Rheumatoid
Methotrexate related adverse effects in patients with rheumatoid arthritis are associated with the A1298C polymorphism of the MTHFR gene.
Arthritis, Rheumatoid
Methylene tetrahydrofolate reductase, transforming growth factor-?1 and lymphotoxin-? genes polymorphisms and susceptibility to rheumatoid arthritis.
Arthritis, Rheumatoid
Methylenetetrahydrofolate reductase and reduced folate carrier-1 genotypes and methotrexate serum concentrations in patients with rheumatoid arthritis.
Arthritis, Rheumatoid
Methylenetetrahydrofolate reductase polymorphisms, C677T and A1298C, are associated with methotrexate-related toxicities in Korean patients with rheumatoid arthritis.
Arthritis, Rheumatoid
MTHFR C677T, MTHFR A1298C, and OPG A163G polymorphisms in Mexican patients with rheumatoid arthritis and osteoporosis.
Arthritis, Rheumatoid
MTHFR functional genetic variation and methotrexate treatment response in rheumatoid arthritis: a meta-analysis.
Arthritis, Rheumatoid
MTHFR gene polymorphisms and outcome of methotrexate treatment in patients with rheumatoid arthritis: analysis of key polymorphisms and meta-analysis of C677T and A1298C polymorphisms.
Arthritis, Rheumatoid
MTHFR gene polymorphisms and susceptibility to rheumatoid arthritis: a meta-analysis based on 16 studies.
Arthritis, Rheumatoid
MTHFR polymorphisms, C677T and A1298C, are not a genetic risk factor for liver stiffness index in methotrexate-treated rheumatoid arthritis patients.
Arthritis, Rheumatoid
MTHFR, TYMS and SLCO1B1 polymorphisms and adverse liver effects of methotrexate in rheumatoid arthritis.
Arthritis, Rheumatoid
MTRR A66G, RFC1 G80A, and MTHFR C677T and A1298C Polymorphisms and Disease Activity in Mexicans with Rheumatoid Arthritis Treated with Methotrexate.
Arthritis, Rheumatoid
No correlation between MTHFR c.677 C?>?T, MTHFR c.1298 A?>?C, and ABCB1 c.3435 C?>?T polymorphisms and methotrexate therapeutic outcome of rheumatoid arthritis in West Algerian population.
Arthritis, Rheumatoid
Plasma total homocysteine level and methylenetetrahydrofolate reductase 677C>T genetic polymorphism in Japanese patients with rheumatoid arthritis.
Arthritis, Rheumatoid
Polymorphisms C677T and A1298C in the MTHFR gene in Mexican patients with rheumatoid arthritis treated with methotrexate: implication with elevation of transaminases.
Arthritis, Rheumatoid
Polymorphisms in the methylenetetrahydrofolate reductase gene were associated with both the efficacy and the toxicity of methotrexate used for the treatment of rheumatoid arthritis, as evidenced by single locus and haplotype analyses.
Arthritis, Rheumatoid
Polymorphisms in the thymidylate synthase and methylenetetrahydrofolate reductase genes and sensitivity to the low-dose methotrexate therapy in patients with rheumatoid arthritis.
Arthritis, Rheumatoid
Prediction of methotrexate clinical response in Portuguese rheumatoid arthritis patients: implication of MTHFR rs1801133 and ATIC rs4673993 polymorphisms.
Arthritis, Rheumatoid
Racial or ethnic differences in allele frequencies of single-nucleotide polymorphisms in the methylenetetrahydrofolate reductase gene and their influence on response to methotrexate in rheumatoid arthritis.
Arthritis, Rheumatoid
Short Communication: Lack of association between MTHFR gene polymorphisms and response to methotrexate treatment in Pakistani patients with rheumatoid arthritis.
Arthritis, Rheumatoid
The c.1298A>C polymorphism in the methylenetetrahydrofolate reductase gene is associated with rheumatoid arthritis susceptibility in Italian patients.
Arthritis, Rheumatoid
The C677T mutation in the methylenetetrahydrofolate reductase gene: a genetic risk factor for methotrexate-related elevation of liver enzymes in rheumatoid arthritis patients.
Arthritis, Rheumatoid
The C677T polymorphism in the MTHFR gene is associated with the toxicity of methotrexate in a Spanish rheumatoid arthritis population.
Arthritis, Rheumatoid
The effect of 677C>T and 1298A>C MTHFR polymorphisms on sulfasalazine treatment outcome in rheumatoid arthritis.
Arthritis, Rheumatoid
The impact of C677T and A1298C MTHFR polymorphisms on methotrexate therapeutic response in East Bohemian region rheumatoid arthritis patients.
Arthritis, Rheumatoid
The plausible association of MTHFR and ADORA2A polymorphisms with nodules in rheumatoid arthritis patients treated with methotrexate.
Arthritis, Rheumatoid
[Methylenetetrahydrofolate reductase polymorphisms in methotrexate treatment of rheumatoid arthritis patients. Review of the literature and personal experience.]
Asthenozoospermia
[The effect of polymorphisms C677T and 1298 gene MTHFR on the reproductive function of men].
Asthma
Ethnic-specific associations of rare and low-frequency DNA sequence variants with asthma.
Asthma
Maternal folic acid use during pregnancy, methylenetetrahydrofolate reductase gene polymorphism, and child's lung function and asthma.
Asthma
Neonatal folate, homocysteine, vitamin B12 levels and methylenetetrahydrofolate reductase variants in childhood asthma and eczema.
Asthma
Relationship between MTHFR gene polymorphism and susceptibility to bronchial asthma and glucocorticoid efficacy in children.
Asthma
The association between mother and child MTHFR C677T polymorphisms, dietary folate intake and childhood atopy in a population-based, longitudinal birth cohort.
Asthma
[Methylenetetrahydrofolate reductase [correction of reducatase] polymorphism and asthma]
Asthma
[Polymorphisms in xenobiotic-metabolizing genes in the pathogenesis of glucocorticoid-induced osteoporosis in patients with bronchial asthma].
Atherosclerosis
A1298C polymorphism in the MTHFR gene predisposes to cardiovascular risk in rheumatoid arthritis.
Atherosclerosis
An association of 5,10-methylenetetrahydrofolate reductase (MTHFR) gene polymorphism and common carotid atherosclerosis.
Atherosclerosis
An association of 5,10-Methylenetetrahydrofolate Reductase (MTHFR) gene polymorphism and ischemic stroke.
Atherosclerosis
Assessment of tailor-made prevention of atherosclerosis with folic acid supplementation: randomized, double-blind, placebo-controlled trials in each MTHFR C677T genotype.
Atherosclerosis
Association between Genetic Polymorphisms and Sites of Cervicocerebral Artery Atherosclerosis.
Atherosclerosis
Association of the C677T polymorphism in the MTHFR gene with breast and/or ovarian cancer risk in Jewish women.
Atherosclerosis
Associations of methylenetetrahydrofolate reductase C677T polymorphism with markers of subclinical atherosclerosis: The Cardiovascular Risk in Young Finns Study.
Atherosclerosis
Atherosclerosis in male patients with ankylosing spondylitis: the relation with methylenetetrahydrofolate reductase (C677T) gene polymorphism and plasma homocysteine levels.
Atherosclerosis
Candidate genetic variants in the fibrinogen, methylenetetrahydrofolate reductase, and intercellular adhesion molecule-1 genes and plasma levels of fibrinogen, homocysteine, and intercellular adhesion molecule-1 among various race/ethnic groups: data from the Women's Genome Health Study.
Atherosclerosis
Carrier-state of D allele in ACE gene insertion/deletion polymorphism is associated with coronary artery disease, in contrast to the C677-->T transition in the MTHFR gene.
Atherosclerosis
Contribution of MTHFR gene variants in lupus related subclinical atherosclerosis.
Atherosclerosis
Croatian population data for the C677T polymorphism in methylenetetrahydrofolate reductase: frequencies in healthy and atherosclerotic study groups.
Atherosclerosis
Effect of MTHFR Gene Polymorphism Impact on Atherosclerosis via Genome-Wide Methylation.
Atherosclerosis
Endothelial nitric oxide synthase and methylenetetrahydrofolate reductase gene polymorphisms are associated with endothelial dysfunction in young, healthy men.
Atherosclerosis
Evaluation of high sensitive C-reactive protein and 5-10 methylenetetrahydrofolate reductase genotype in japanese young adults.
Atherosclerosis
Expression of the C677T Polymorphism of the 5, 10-Methylenetetrahydrofolate Reductase (MTHFR) Gene in Patients with Carotid Artery Atherosclerosis.
Atherosclerosis
Genetic contributors and soluble mediators in prediction of autoimmune comorbidity.
Atherosclerosis
Homocysteine, endothelial dysfunction, and coronary artery disease: emerging strategy for secondary prevention.
Atherosclerosis
Hypertrophy of IMC of carotid artery in Parkinson's disease is associated with L-DOPA, homocysteine, and MTHFR genotype.
Atherosclerosis
Interaction between Mediterranean diet and methylenetetrahydrofolate reductase C677T mutation on oxidized low density lipoprotein concentrations: The ATTICA study.
Atherosclerosis
Lack of carotid stiffening associated with MTHFR 677TT genotype in cardiorespiratory fit adults.
Atherosclerosis
Methylenetetrahydrofolate reductase polymorphism 677C>T is associated with peripheral arterial disease in type 2 diabetes.
Atherosclerosis
Methylenetetrahydrofolate reductase polymorphism determines the plasma homocysteine-lowering effect of large-dose folic acid supplementation in patients with cardiovascular disease.
Atherosclerosis
MTHFR 677 C>T Polymorphism reveals functional importance for 5-methyltetrahydrofolate, not homocysteine, in regulation of vascular redox state and endothelial function in human atherosclerosis.
Atherosclerosis
MTHFR C677T mutation increased the risk of Ischemic Stroke, especially in large-artery atherosclerosis in adults: an updated meta-analysis from 38 researches.
Atherosclerosis
Multiple thrombophilia mutations as a possible cause of premature myocardial infarction.
Atherosclerosis
No associations of Helicobacter pylori infection and gastric atrophy with plasma total homocysteine in Japanese.
Atherosclerosis
Plasma homocyst(e)ine concentration, but not MTHFR genotype, is associated with variation in carotid plaque area.
Atherosclerosis
Plasma total homocysteine and the methylenetetrahydrofolate reductase 677C>T polymorphism do not contribute to the distribution of cervico-cerebral atherosclerosis in ischaemic stroke patients.
Atherosclerosis
Serum homocysteine, methylenetetrahydrofolate reductase gene polymorphism and cardiovascular disease in heterozygous familial hypercholesterolemia.
Atherosclerosis
Serum total homocysteine, folate, 5,10-methylenetetrahydrofolate reductase (MTHFR) 677C-->T genotype and subclinical atherosclerosis.
Atherosclerosis
Smoking Confers a MTHFR 677C>T Genotype-Dependent Risk for Systemic Atherosclerosis: Results from a Large Number of Elderly Autopsy Cases that Died in a Community-Based General Geriatric Hospital.
Atherosclerosis
Sonographic evaluation of atherosclerosis burden in carotid arteries of ischemic stroke patients and its relation to paraoxonase 1 and 2, MTHFR and AT1R genetic variants.
Atherosclerosis
The 1316T>C missenses mutation in MTHFR contributes to MTHFR deficiency by targeting MTHFR to proteasome degradation.
Atherosclerosis
The effect of a common methylenetetrahydrofolate reductase mutation on levels of homocysteine, folate, vitamin B12 and on the risk of premature atherosclerosis.
Atherosclerosis
The effects of diet, genetics and chemicals on toxicity and aberrant DNA methylation: an introduction.
Atherosclerosis
The Relationship of Methylenetetrahydrofolate Reductase Gene C677T Polymorphism and Ischemic Stroke in Chinese Han Population.
Atherosclerosis
The SNP Rs915014 in MTHFR Regulated by MiRNA Associates with Atherosclerosis.
Atherosclerosis
[Features of allele polymorphism of genes involved in homocysteine and folate metabolism in patients with atherosclerosis of the lower extremity arteries]
Atherosclerosis
[Homocysteinemia and thrombophilic factors in unexplained decompression sickness]
Atrial Fibrillation
Ischemic Stroke in a Patient With Atrial Tachycardia, Methylenetetrahydrofolate Reductase Mutation and New-Onset Atrial Fibrillation: Is Early Initiation of Anticoagulation Therapy Indicated?
Atrial Fibrillation
Rivaroxaban as an effective alternative to warfarin in a patient with atrial fibrillation, thrombophilia, and left atrial appendage thrombus: a case report.
Atrial Fibrillation
Role of C677T and A1298C MTHFR, A2756G MTR and -786 C/T eNOS gene polymorphisms in atrial fibrillation susceptibility.
Atrial Fibrillation
The factor V Leiden, prothrombin gene 20210GA, methylenetetrahydrofolate reductase 677CT and platelet glycoprotein IIIa 1565TC mutations in patients with acute ischemic stroke and atrial fibrillation.
Atrial Fibrillation
[Interrelationship between polymorphic markers of methylenetetrahydrofolate reductase gene and development of acute disturbance of brain circulation in families of patients with atrial fibrillation].
Autoimmune Diseases
Association of methylenetetrahydrofolate reductase gene C677T polymorphism with multiple sclerosis in Turkish patients.
Autoimmune Diseases
Association of MTHFR C677T polymorphism with elevated homocysteine level and disease development in vitiligo.
Autoimmune Diseases
Association study between methylenetetrahydrofolate reductase gene polymorphisms and Graves' disease.
Autoimmune Diseases
Ill-defined neurological syndromes with autoimmune background: a diagnostic challenge.
Autoimmune Diseases
The protective effects of the methylenetetrahydrofolate reductase rs1801131 variant among Saudi smokers.
Avitaminosis
An unusually high plasma concentration of homocysteine resulting from a combination of so-called "secondary" etiologies.
Avitaminosis
Antiepileptic drug-induced psychosis associated with MTHFR C677T: a case report.
Avitaminosis
Contribution of the MTHFR gene to the causal pathway for depression, anxiety and cognitive impairment in later life.
Avitaminosis
Effect of folate, vitamin B6, and vitamin B12 intake and MTHFR C677T polymorphism on homocysteine concentrations of renal transplant recipients.
Avitaminosis
G1793A polymorphisms in the methylene-tetrahydrofolate gene: effect of folic acid on homocysteine levels.
Azoospermia
Association between genetic polymorphisms in folate-related enzyme genes and infertile men with non-obstructive azoospermia.
Azoospermia
Association of a miR-34b binding site single nucleotide polymorphism in the 3'-untranslated region of the methylenetetrahydrofolate reductase gene with susceptibility to male infertility.
Azoospermia
Association of the methylenetetrahydrofolate reductase gene A1298C polymorphism with male infertility: a meta-analysis.
Azoospermia
Association of the methylenetetrahydrofolate reductase gene C677T polymorphism with the risk of male infertility: a meta-analysis.
Azoospermia
Association study of four polymorphisms in three folate-related enzyme genes with non-obstructive male infertility.
Azoospermia
Chromosomal aberration leads to recurrent pregnancy loss and partial trisomy of 5p12-15.3 in the offspring: report of a Syrian couple and review of the literature .
Azoospermia
Evaluation of association between methylenetetrahydrofolate reductase and azoospermia: A meta-analysis.
Azoospermia
Evaluation of association between methylenetetrahydrofolate reductase and azoospermia: A meta-analysis: Retraction.
Azoospermia
Influence of Methylenetetrahydrofolate Reductase C677T Gene Polymorphisms in Algerian Infertile Men with Azoospermia or Severe Oligozoospermia.
Azoospermia
Methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and male infertility risk: An updated meta-analysis.
Azoospermia
Methylenetetrahydrofolate reductase C677T polymorphism and the risk of male infertility: a meta-analysis.
Azoospermia
Methylenetetrahydrofolate reductase polymorphisms are related to male infertility in Brazilian men.
Azoospermia
MTHFR promoter hypermethylation in testicular biopsies of patients with non-obstructive azoospermia: the role of epigenetics in male infertility.
Azoospermia
Single nucleotide polymorphism C677T in the methylenetetrahydrofolate reductase gene might be a genetic risk factor for infertility for Chinese men with azoospermia or severe oligozoospermia.
Bacterial Infections
Review article: the aetiology of primary Budd-Chiari syndrome - differences between the West and China.
Barrett Esophagus
Association of methylenetetrahydrofolate reductase C677T-A1298C polymorphisms with risk for esophageal adenocarcinoma, Barrett's esophagus, and reflux esophagitis.
Behcet Syndrome
Methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and variations of homocysteine concentrations in patients with Behcet's disease.
Behcet Syndrome
Recurrent Myocardial Infarction Despite Normal C-reactive Protein in a Patient with Behcet's Disease and Compound Heterozygous Methylenetetrahydrofolate Reductase (MTHFR) Mutations (C677T and A1298C).
beta-Thalassemia
Atypical hemolytic uremic syndrome with peripheral gangrene and homocysteinemia in a child.
beta-Thalassemia
Hypercoagulable state and methylenetetrahydrofolate reductase (MTHFR) C677T mutation in patients with beta-thalassemia major in Kuwait.
beta-Thalassemia
MTHFR C677T, Prothrombin G20210A, and Factor V Leiden (G1691A) Polymorphism and Beta-Thalassemia Risk: A Meta-Analysis.
beta-Thalassemia
Prevalence of Factor V Leiden G1691A, MTHFR C677T, and Prothrombin G20210A Among Asian Indian Sickle Cell Patients.
beta-Thalassemia
Prevalence of thrombotic risk factors among beta-thalassemia patients from Western Iran.
beta-Thalassemia
The prevalence of factor V Leiden (G1691A), prothrombin G20210A and methylenetetrahydrofolate reductase C677T mutations in Jordanian patients with beta-thalassemia major.
Biotinidase Deficiency
Epidemiology of rare diseases detected by newborn screening in the Czech Republic.
Bladder Exstrophy
Bladder exstrophy-epispadias complex and the role of methylenetetrahydrofolate reductase C677T polymorphism: A case control study.
Bladder Exstrophy
MTHFR 677 TT genotype in a mother and her child with Down syndrome, atrioventricular canal and exstrophy of the bladder: implications of a mutual genetic risk factor?
Bone Diseases, Metabolic
A common methylenetetrahydrofolate reductase (C677T) polymorphism is associated with low bone mineral density and increased fracture incidence after menopause: longitudinal data from the Danish osteoporosis prevention study.
Bone Diseases, Metabolic
Association of plasma folate, plasma total homocysteine, but not methylenetetrahydrofolate reductase C667T polymorphism, with bone mineral density in postmenopausal Iranian women: a cross-sectional study.
Bone Resorption
Association of Blood Lead Levels with Methylenetetrahydrofolate Reductase Polymorphisms among Chinese Pregnant Women in Wuhan City.
Bone Resorption
Hyperhomocysteinemia is Associated with Inflammation, Bone Resorption, Vitamin B12 and Folate Deficiency and MTHFR C677T Polymorphism in Postmenopausal Women with Decreased Bone Mineral Density.
Brain Diseases
Adolescence/adult onset MTHFR deficiency may manifest as isolated and treatable distinct neuro-psychiatric syndromes.
Brain Diseases
Betaine for treatment of homocystinuria caused by methylenetetrahydrofolate reductase deficiency.
Brain Diseases
Clinical presentation, etiology, and outcome of stroke in children: A hospital-based study.
Brain Diseases
Diagnostic yield of genetic testing in epileptic encephalopathy in childhood.
Brain Diseases
Intermittent encephalopathy, reversible nerve conduction slowing, and MRI evidence of cerebral white matter disease in methylenetetrahydrofolate reductase deficiency.
Brain Diseases
Methylenetetrahydrofolate reductase (MTHFR) deficiency and infantile epilepsy.
Brain Diseases
Pearls & oy-sters: familial epileptic encephalopathy due to methylenetetrahydrofolate reductase deficiency.
Brain Diseases
[Genotype and phenotype analysis of neonates with neonatal encephalopathy complicated with perinatal hypoxic event].
Brain Infarction
Association of methylenetetrahydrofolate reductase (MTHFR 677C>T and 1298A>C) polymorphisms and haplotypes with silent brain infarction and homocysteine levels in a Korean population.
Brain Infarction
Effect of methylenetetrahydrofolate reductase gene polymorphisms and oxidative stress in silent brain infarction.
Brain Infarction
Hyperhomocysteinemia as an independent risk factor for silent brain infarction.
Brain Infarction
MTHFR C677T and prothrombin G20210A mutations in a woman from Dalmatia with silent brain infarction. .
Brain Infarction
MTHFR gene polymorphism as a risk factor for silent brain infarcts and white matter lesions in the Japanese general population: The NILS-LSA Study.
Brain Infarction
[Study on homocysteine metabolism related enzymes gene mutations in Chinese patients with ischemic cardiovascular and cerebrovascular diseases]
Brain Injuries
Maternal mutation 677C > T in the methylenetetrahydrofolate reductase gene associated with severe brain injury in offspring.
Brain Injuries, Traumatic
Pathomorphology of inflammatory response following traumatic brain injury, serum values of interleukins, and gene polymorphisms.
Brain Ischemia
Methylenetetrahydrofolate reductase gene polymorphisms in patients with cerebral hemorrhage.
Brain Ischemia
Risk factors of cerebral ischemia in infants born to mothers with gestational diabetes.
Brain Ischemia
[A clinical and genetic analysis of risk factors for the development of acute and chronic cerebral ischemia].
Brain Neoplasms
C677T gene polymorphism of methylenetetrahydrofolate reductase (MTHFR) in meningiomas and high-grade gliomas.
Brain Neoplasms
Functional polymorphisms in folate metabolism genes influence the risk of meningioma and glioma.
Brain Neoplasms
Intranasal perillyl alcohol therapy improves survival of patients with recurrent glioblastoma harboring mutant variant for MTHFR rs1801133 polymorphism.
Brain Neoplasms
MTHFR single nucleotide polymorphism associated with working memory in pediatric medulloblastoma survivors.
Brain Neoplasms
Polymorphisms of Folate Pathway Enzymes (Methylenetetrahydrofolate Reductase and Thymidylate Synthase) and Their Relationship with Thymidylate Synthase Expression in Human Astrocytic Tumors.
Brain Neoplasms
Risk association of meningiomas with MTHFR C677T and GSTs polymorphisms: a meta-analysis.
Breast Neoplasms
A candidate CpG SNP approach identifies a breast cancer associated ESR1-SNP.
Breast Neoplasms
A meta-analysis of genotypes and haplotypes of methylenetetrahydrofolate reductase gene polymorphisms in breast cancer.
Breast Neoplasms
Aberrations in one-carbon metabolism induce oxidative DNA damage in sporadic breast cancer.
Breast Neoplasms
Alcohol consumption and genetic variation in methylenetetrahydrofolate reductase and 5-methyltetrahydrofolate-homocysteine methyltransferase in relation to breast cancer risk.
Breast Neoplasms
Association Analysis of Methylenetetrahydrofolate Reductase Common Gene Polymorphisms with Breast Cancer Risk in an Iranian Population: A Case-Control Study and a Stratified Analysis.
Breast Neoplasms
Association between dietary intake of folate and MTHFR and MTR genotype with risk of breast cancer.
Breast Neoplasms
Association between dietary intake of folate, vitamin B6, B12 & MTHFR, MTR Genotype and breast cancer risk.
Breast Neoplasms
Association between MTHFR 677C/T and 1298A/C gene polymorphisms and breast cancer risk.
Breast Neoplasms
Association between MTHFR gene 1298A>C polymorphism and breast cancer susceptibility: a meta-analysis based on 38 case-control studies with 40,985 subjects.
Breast Neoplasms
Association between the MTHFR C677T Polymorphism and Breast Cancer Risk: A Meta-Analysis of 23 Case-Control Studies.
Breast Neoplasms
Association between the MTHFR C677T polymorphism and risk of cancer: evidence from 446 case-control studies.
Breast Neoplasms
Association of 677 C>T (rs1801133) and 1298 A>C (rs1801131) polymorphisms in the MTHFR gene and breast cancer susceptibility: a meta-analysis based on 57 individual studies.
Breast Neoplasms
Association of C677T (rs1081133) and A1298C (rs1801131) Methylenetetrahydrofolate Reductase Variants with Breast Cancer Susceptibility Among Asians: A Systematic Review and Meta-Analysis.
Breast Neoplasms
Association of dietary intake of folate and MTHFR genotype with breast cancer risk.
Breast Neoplasms
Association of dietary intake of folate, vitamin B6 and B12 and MTHFR genotype with breast cancer risk.
Breast Neoplasms
Association of genetic polymorphisms with hepatotoxicity in patients with childhood acute lymphoblastic leukemia or lymphoma.
Breast Neoplasms
Association of Intake Folate and Related Gene Polymorphisms with Breast Cancer.
Breast Neoplasms
Association of methylenetetrahydrofolate reductase and methionine synthase polymorphisms with breast cancer risk and interaction with folate, vitamin B6, and vitamin B 12 intakes.
Breast Neoplasms
Association of MTHFR (C677T) Gene Polymorphism With Breast Cancer in North India.
Breast Neoplasms
ASSOCIATION OF MTHFR A1298C POLYMORPHISM WITH BREAST CANCER AND/OR OVARIAN CANCER RISK: AN UPDATED META-ANALYSIS.
Breast Neoplasms
Association of physical activity and polymorphisms in FGFR2 and DNA methylation related genes with breast cancer risk.
Breast Neoplasms
Association of polymorphisms in one-carbon metabolizing genes with breast cancer risk in Syrian women.
Breast Neoplasms
Association of the C677T polymorphism in the methylenetetrahydrofolate reductase gene with breast cancer in a Mexican population.
Breast Neoplasms
Association of the MTHFR Gene C677T Polymorphism with Breast Cancer in a Turkish Population.
Breast Neoplasms
Associations of polymorphisms of folate cycle enzymes and risk of breast cancer in a Brazilian population are age dependent.
Breast Neoplasms
Biomarkers of folate and vitamin B12 and breast cancer risk: report from the EPIC cohort.
Breast Neoplasms
Breast cancer risk associated with gene expression and genotype polymorphisms of the folate-metabolizing MTHFR gene: a case-control study in a high altitude Ecuadorian mestizo population.
Breast Neoplasms
Breast cancer risk, dietary intake, and methylenetetrahydrofolate reductase (MTHFR)single nucleotide polymorphisms.
Breast Neoplasms
C677T and A1298C methylenetetrahydrofolate reductase polymorphisms and breast cancer susceptibility among Latinos: a meta-analysis.
Breast Neoplasms
Can MTHFR C677T and A1298C Polymorphisms Alter the Risk and Severity of Sporadic Breast Cancer in Brazilian Women?
Breast Neoplasms
Combined impact of polymorphism of folate metabolism genes; glutamate carboxypeptidase, methylene tetrahydrofolate reductase and methionine synthase reductase on breast cancer susceptibility in kashmiri women.
Breast Neoplasms
Controversial roles of methylenetetrahydrofolate reductase polymorphisms and folate in breast cancer disease.
Breast Neoplasms
Cumulative review and meta-analyses on the association between MTHFR rs1801133 polymorphism and breast cancer risk: a pooled analysis of 83 studies with 74,019 participants.
Breast Neoplasms
Dietary intake of folate, vitamin B2, vitamin B6, vitamin B12, genetic polymorphism of related enzymes, and risk of breast cancer: a case-control study in Japan.
Breast Neoplasms
Dietary intake of folate, vitamin B6, and vitamin B12, genetic polymorphism of related enzymes, and risk of breast cancer: a case-control study in Brazilian women.
Breast Neoplasms
Dihydrofolate reductase (DHRF) 19-bp intron-1 deletion and methylenetetrahydrofolate reductase (MTHFR) C677T polymorphisms in breast cancer.
Breast Neoplasms
Distribution of TYMS, MTHFR, p53 and MDR1 gene polymorphisms in patients with breast cancer treated with neoadjuvant chemotherapy.
Breast Neoplasms
DNA promoter methylation in breast tumors: no association with genetic polymorphisms in MTHFR and MTR.
Breast Neoplasms
Do single nucleotide polymorphisms in xenobiotic metabolizing genes determine breast cancer susceptibility and treatment outcomes?
Breast Neoplasms
Effect of the methylenetetrahydrofolate reductase C677T polymorphism on chemosensitivity of colon and breast cancer cells to 5-fluorouracil and methotrexate.
Breast Neoplasms
Effect of the methylenetetrahydrofolate reductase gene C677T polymorphism on C-erbB-2 methylation status and its association with cancer.
Breast Neoplasms
Effects of methylenetetrahydrofolate reductase single-nucleotide polymorphisms on breast, cervical, ovarian, and endometrial cancer susceptibilities.
Breast Neoplasms
Epistatic interactions between loci of one-carbon metabolism modulate susceptibility to breast cancer.
Breast Neoplasms
Evaluation of the contribution of methylenetetrahydrofolate reductase genotypes to Taiwan breast cancer.
Breast Neoplasms
Evaluation of the two polymorphisms rs1801133 in MTHFR and rs10811661 in CDKN2A/B in breast cancer.
Breast Neoplasms
Evidence of Association Between Methylenetetrahydrofolate Reductase Gene and Susceptibility to Breast Cancer: A Candidate-Gene Association Study in a South-Eastern European Population.
Breast Neoplasms
Extent of differential allelic expression of candidate breast cancer genes is similar in blood and breast.
Breast Neoplasms
Factor V Leiden, prothrombin G20210A and methylenetetrahydrofolate reductase (MTHFR) C677T polymorphisms and the risk of tamoxifen-associated thromboembolism in breast cancer patients.
Breast Neoplasms
Folate and breast cancer: the role of polymorphisms in methylenetetrahydrofolate reductase (MTHFR).
Breast Neoplasms
Folate intake, methylenetetrahydrofolate reductase polymorphisms, and breast cancer risk in women from the Malmö Diet and Cancer cohort.
Breast Neoplasms
Gene polymorphisms in TYMS, MTHFR, p53 and MDR1 as risk factors for breast cancer: a case-control study.
Breast Neoplasms
Generalized Multifactor Dimensionality Reduction (GMDR) Analysis of Drug-Metabolizing Enzyme-Encoding Gene Polymorphisms may Predict Treatment Outcomes in Indian Breast Cancer Patients.
Breast Neoplasms
Genetic polymorphisms associated with adverse events and elimination of methotrexate in childhood acute lymphoblastic leukemia and malignant lymphoma.
Breast Neoplasms
Genetic polymorphisms in the one-carbon metabolism pathway and breast cancer risk: a population-based case-control study and meta-analyses.
Breast Neoplasms
Genetic polymorphisms of the methylenetetrahydrofolate reductase gene, plasma folate levels and breast cancer susceptibility: a case-control study in Taiwan.
Breast Neoplasms
Genetic profile and determinants of homocysteine levels in Kazakhstan patients with breast cancer.
Breast Neoplasms
Germ-line MTHFR C677T, FV H1299R and PAI-1 5G/4G Variations in Breast Carcinoma.
Breast Neoplasms
Global DNA methylation and one-carbon metabolism gene polymorphisms and the risk of breast cancer in the Sister Study.
Breast Neoplasms
Green tea intake, MTHFR/TYMS genotype and breast cancer risk: the Singapore Chinese Health Study.
Breast Neoplasms
GSTP1 and MTHFR polymorphisms are related with toxicity in breast cancer adjuvant anthracycline-based treatment.
Breast Neoplasms
Haplotypes of the MTHFR gene are associated with an increased risk of breast cancer in a Han Chinese population in Gansu province.
Breast Neoplasms
HFE, MTHFR, and FGFR4 genes polymorphisms and breast cancer in Brazilian women.
Breast Neoplasms
Homozygosity at the C677T of the MTHFR gene is associated with increased breast cancer risk in the Turkish population.
Breast Neoplasms
Increased breast cancer risk at high plasma folate concentrations among women with the MTHFR 677T allele.
Breast Neoplasms
Influence of chemotherapeutic drug-related gene polymorphisms on toxicity and survival of early breast cancer patients receiving adjuvant chemotherapy.
Breast Neoplasms
Influence of Estrogenic Metabolic Pathway Genes Polymorphisms on Postmenopausal Breast Cancer Risk.
Breast Neoplasms
Influence of thymidylate synthase and methylenetetrahydrofolate reductase gene polymorphisms on the disease-free survival of breast cancer patients receiving adjuvant 5-fluorouracil/methotrexate-based therapy.
Breast Neoplasms
Interaction of MTHFR C677T and A1298C, and MTR A2756G gene polymorphisms in breast cancer risk in a population in Northeast Brazil.
Breast Neoplasms
Interactions Between MTHFR C677T - A1298C Variants and Folic Acid Deficiency Affect Breast Cancer Risk in a Chinese Population.
Breast Neoplasms
Investigation of Methylenetetrahydrofolate Reductase C677T Polymorphism and Human Papilloma Virus Genotypes in Iranian Breast Cancer.
Breast Neoplasms
Joint effects between urinary selenium and polymorphisms in methylation related genes on breast cancer risk.
Breast Neoplasms
Joint effects of folate intake and one-carbon-metabolizing genetic polymorphisms on breast cancer risk: a case-control study in China.
Breast Neoplasms
Lack of association between methylenetetrahydrofolate reductase gene A1298C polymorphism and breast cancer susceptibility.
Breast Neoplasms
Lack of association between methylenetetrahydrofolate reductase genetic polymorphisms and postmenopausal breast cancer risk.
Breast Neoplasms
Lack of association between MHTFR Glu429Ala polymorphism and breast cancer susceptibility: a systematic review and meta-analysis of 29 research studies.
Breast Neoplasms
Lack of association between MTHFR C677T polymorphism and breast cancer risk in Ahvaz, west south-Iran.
Breast Neoplasms
Meta-analyses of observational and genetic association studies of folate intakes or levels and breast cancer risk.
Breast Neoplasms
Methionine-Dependence Phenotype in the de novo Pathway in BRCA1 and BRCA2 Mutation Carriers with and without Breast Cancer.
Breast Neoplasms
Methylenetetrahydrofolate reductase (MTHFR) and breast cancer risk: a nested-case-control study and a pooled meta-analysis.
Breast Neoplasms
Methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms in breast cancer: a Sardinian preliminary case-control study.
Breast Neoplasms
Methylenetetrahydrofolate Reductase A1298C Polymorphism and Breast Cancer Risk: A Meta-analysis of 33 Studies.
Breast Neoplasms
Methylenetetrahydrofolate reductase and thymidylate synthase polymorphisms are not associated with breast cancer risk or phenotype.
Breast Neoplasms
Methylenetetrahydrofolate reductase C677T polymorphism and breast cancer risk in Moroccan women.
Breast Neoplasms
Methylenetetrahydrofolate reductase C677T polymorphism in breast cancer risk.
Breast Neoplasms
Methylenetetrahydrofolate reductase gene and susceptibility to breast cancer: a meta-analysis.
Breast Neoplasms
Methylenetetrahydrofolate reductase gene C677T polymorphism and breast cancer risk: Evidence for genetic susceptibility.
Breast Neoplasms
Methylenetetrahydrofolate reductase haplotype tag single-nucleotide polymorphisms and risk of breast cancer.
Breast Neoplasms
Methylenetetrahydrofolate reductase polymorphism and susceptibility to breast cancer.
Breast Neoplasms
Methylenetetrahydrofolate reductase polymorphism, diet, and breast cancer in Korean women.
Breast Neoplasms
Methylenetetrahydrofolate reductase polymorphisms and breast cancer risk in Chinese population: a meta-analysis of 22 case-control studies.
Breast Neoplasms
Methylenetetrahydrofolate reductase polymorphisms and breast cancer risk: a meta-analysis from 41 studies with 16,480 cases and 22,388 controls.
Breast Neoplasms
MTHFR 677C>T polymorphism and the risk of breast cancer: evidence from an original study and pooled data for 28031 cases and 31880 controls.
Breast Neoplasms
MTHFR C677T and A1298C Polymorphisms in Breast Cancer, Gliomas and Gastric Cancer: A Review.
Breast Neoplasms
MTHFR C677T and postmenopausal breast cancer risk by intakes of one-carbon metabolism nutrients: a nested case-control study.
Breast Neoplasms
MTHFR C677T polymorphism associated with breast cancer susceptibility: a meta-analysis involving 15,260 cases and 20,411 controls.
Breast Neoplasms
MTHFR gene A1298C polymorphisms are associated with breast cancer risk among Chinese population: evidence based on an updated cumulative meta-analysis.
Breast Neoplasms
MTHFR gene polymorphism and severe toxicity during adjuvant treatment of early breast cancer with cyclophosphamide, methotrexate, and fluorouracil (CMF)
Breast Neoplasms
MTHFR Gene Polymorphism-Mutations and Air Pollution as Risk Factors for Breast Cancer: A Metaprediction Study.
Breast Neoplasms
MTHFR genotypes and breast cancer survival after surgery and chemotherapy: a report from the Shanghai Breast Cancer Study.
Breast Neoplasms
MTHFR polymorphisms, diet, HRT, and breast cancer risk: the multiethnic cohort study.
Breast Neoplasms
MTHFR polymorphisms, dietary folate intake and breast cancer risk in Chinese women.
Breast Neoplasms
MTHFR polymorphisms, dietary folate intake, and breast cancer risk: results from the Shanghai Breast Cancer Study.
Breast Neoplasms
MTHFR, XRCC1 and OGG1 genetic polymorphisms in breast cancer: a case-control study in a population from North Sardinia.
Breast Neoplasms
Multiple Genetic Polymorphisms of GSTP1 313AG, MDR1 3435CC, and MTHFR 677CC highly correlated with early relapse of breast cancer patients in Taiwan.
Breast Neoplasms
Mutational analysis of the MTHFR gene in breast cancer patients of Pakistani population.
Breast Neoplasms
No association between cSHMT genotypes and the risk of breast cancer in the Nurses' Health Study.
Breast Neoplasms
No association between methylenetetrahydrofolate reductase C677T polymorphism and breast cancer.
Breast Neoplasms
One-carbon metabolism and breast cancer risk: no association of MTHFR, MTR, and TYMS polymorphisms in the GENICA study from Germany.
Breast Neoplasms
One-carbon metabolism-related gene polymorphisms and risk of breast cancer.
Breast Neoplasms
Pharmacogenetics in cancer therapy - 8 years of experience at the Institute for Oncology and Radiology of Serbia.
Breast Neoplasms
Plasma B-vitamins and one-carbon metabolites and the risk of breast cancer in younger women.
Breast Neoplasms
Polymorphism of cytosolic serine hydroxymethyltransferase, estrogen and breast cancer risk among Chinese women in Taiwan.
Breast Neoplasms
Polymorphisms in folate metabolizing enzymes and transport proteins and the risk of breast cancer.
Breast Neoplasms
Polymorphisms in the MTHFR gene are associated with breast cancer risk and prognosis in a Chinese population.
Breast Neoplasms
Polymorphisms in the MTHFR gene are associated with recurrence risk in lymph node-positive breast cancer patients.
Breast Neoplasms
Polymorphisms of 5,10-methylenetetrahydrofolate reductase (MTHFR C677T) and thymidylate synthase enhancer region (TSER) as a risk factor of cholangiocarcinoma in a Korean population.
Breast Neoplasms
Polymorphisms of MTHFR and TYMS predict capecitabine-induced hand-foot syndrome in patients with metastatic breast cancer.
Breast Neoplasms
Polymorphisms of one-carbon-metabolizing genes and risk of breast cancer in a population-based study.
Breast Neoplasms
Population-level diversity in the association of genetic polymorphisms of one-carbon metabolism with breast cancer risk.
Breast Neoplasms
Preventive medical services not covered by public health insurance at Daiko Medical Center in Japan, 2004-2011.
Breast Neoplasms
Reduced breast cancer risk with increasing serum folate in a case-control study of the C677T genotype of the methylenetetrahydrofolate reductase gene.
Breast Neoplasms
Relationship between Genetic Polymorphisms in MTHFR (C677T, A1298C and their Haplotypes) and the Incidence Of Breast Cancer among Jordanian Females--Case-Control Study.
Breast Neoplasms
Relationship between genetic polymorphisms of methylenetetrahydrofolate reductase and breast cancer chemotherapy response.
Breast Neoplasms
Relationship of MTHFR and NQO1 Pharmacogenetics and Chemotherapy Clinical Outcomes in Breast Cancer Patients.
Breast Neoplasms
Retraction notice to Breast Cancer Risk, Dietary Intake, and Methylenetetrahydrofolate reductase (MTHFR) Single Nucleotide Polymorphisms Food and Chemical Toxicology 48/7 (2010) 1881 - 1885.
Breast Neoplasms
Role of MTHFR (677, 1298) haplotype in the risk of developing secondary leukemia after treatment of breast cancer and hematological malignancies.
Breast Neoplasms
Role of MTHFR C677T and MTR A2756G polymorphisms in thyroid and breast cancer development.
Breast Neoplasms
Significant association between ERCC2 and MTHR polymorphisms and breast cancer susceptibility in Moroccan population: genotype and haplotype analysis in a case-control study.
Breast Neoplasms
Strong Correlation of MTHFR Gene Polymorphisms with Breast Cancer and its Prognostic Clinical Factors among Egyptian Females.
Breast Neoplasms
The association between methylenetetrahydrofolate reductase 677C>T polymorphisms and breast cancer susceptibility: A meta-analysis based on Chinese Han population.
Breast Neoplasms
The association between methylenetetrahydrofolate reductase gene C677T polymorphisms and breast cancer risk in Chinese population.
Breast Neoplasms
The association of p53 mutations and p53 codon 72, Her 2 codon 655 and MTHFR C677T polymorphisms with breast cancer in Northern Greece.
Breast Neoplasms
The Association of Protease Activated Receptor 1 gene -506 I/D Polymorphism with Disease-Free Survival in Breast Cancer Patients.
Breast Neoplasms
The common 677C>T gene polymorphism of methylenetetrahydrofolate reductase gene is not associated with breast cancer risk.
Breast Neoplasms
The effect of folate-related SNPs on clinicopathological features, response to neoadjuvant treatment and survival in pre- and postmenopausal breast cancer patients.
Breast Neoplasms
The methylenetetrahydrofolate reductase (MTHFR) C677T gene polymorphism is associated with breast cancer subtype susceptibility in southwestern China.
Breast Neoplasms
The methylenetetrahydrofolate reductase C677T mutation induces cell-specific changes in genomic DNA methylation and uracil misincorporation: a possible molecular basis for the site-specific cancer risk modification.
Breast Neoplasms
The methylenetetrahydrofolate reductase C677T polymorphism and breast cancer risk in Asian populations.
Breast Neoplasms
The MTHFR C677T polymorphism, estrogen exposure and breast cancer risk: a nested case-control study in Taiwan.
Breast Neoplasms
Thrombophilic polymorphisms are not associated with disease-free survival in breast cancer patients.
Breast Neoplasms
TYMS, MTHFR, p53 and MDR1 gene polymorphisms in breast cancer patients treated with adjuvant therapy.
Breast Neoplasms
[Association between genetic polymorphisms in methylenetetrahydrofolate reductase and risk of breast cancer]
Breast Neoplasms
[C677T-SNP of methylenetetrahydrofolate reductase gene and breast cancer in Mexican women].
Breast Neoplasms
[Polymorphic variants of folate metabolizing genes (C677T and A1298C MTHFR, C1420T SHMT1 and G1958A MTHFD) are not associated with the risk of breast cancer in West Siberian Region of Russia].
Budd-Chiari Syndrome
Abdominal venous thrombosis in neonates and infants: role of prothrombotic risk factors - a multicentre case-control study. For the Childhood Thrombophilia Study Group.
Budd-Chiari Syndrome
Association of factor V Leiden, Janus kinase 2, prothrombin, and MTHFR mutations with primary Budd-Chiari syndrome in Egyptian patients.
Budd-Chiari Syndrome
Budd-Chiari syndrome in a paroxysmal nocturnal hemoglobinuria patient with coexistence of factor II and MTHFR mutations.
Budd-Chiari Syndrome
Budd-Chiari syndrome with underlying homozygous factor V Leiden and heterozygous methylenetetrahydrofolate reductase mutations.
Budd-Chiari Syndrome
Compound heterozygosity for factor V and methylenetetrahydrofolate reductase mutations in a patient with Budd-Chiari syndrome.
Budd-Chiari Syndrome
Hyperhomocysteinemia and the MTHFR C677T mutation in Budd-Chiari syndrome.
Budd-Chiari Syndrome
Methylenetetrahydrofolate reductase C677T gene mutation and hyperhomocysteinemia in Budd-Chiari syndrome and portal vein thrombosis: A systematic review and meta-analysis of observational studies.
Carcinogenesis
A case-control nutrigenomic study on the synergistic activity of folate and vitamin B12 in cervical cancer progression.
Carcinogenesis
A case-control study of methylenetetrahydrofolate reductase polymorphisms in cervical carcinogenesis.
Carcinogenesis
A prospective study of methylenetetrahydrofolate reductase and methionine synthase gene polymorphisms, and risk of colorectal adenoma.
Carcinogenesis
Analysis of relation between C677T genotype in MTHFR gene and prostatic cancer in Iranian males.
Carcinogenesis
Are the methylenetetrahydrofolate reductase 1298 and 677 gene polymorphisms related to optic glioma and hamartoma risk in neurofibromatosis type 1 patients?
Carcinogenesis
Association between methylenetetrahydrofolate reductase polymorphism C677T and risk of chronic myeloid leukemia in Serbian population.
Carcinogenesis
Association between methylenetetrahydrofolate reductase polymorphisms, alcohol intake and oropharyngolaryngeal carcinoma in northern Italy.
Carcinogenesis
Association between MTHFR C677T, MTHFR A1298C and MS A2756G polymorphisms and risk of cervical intraepithelial neoplasia II/III and cervical cancer: A meta-analysis.
Carcinogenesis
Association between polymorphisms of folate-metabolizing enzymes and risk of prostate cancer.
Carcinogenesis
Association of methylenetetrahydrofolate reductase and thymidylate synthase promoter polymorphisms with genetic susceptibility to esophageal and cardia cancer in a Chinese high-risk population.
Carcinogenesis
Association of methylenetetrahydrofolate reductase C677T-A1298C polymorphisms with risk for esophageal adenocarcinoma, Barrett's esophagus, and reflux esophagitis.
Carcinogenesis
Association of polymorphisms MTHFR C677T and A1298C with risk of colorectal cancer, genetic and epigenetic characteristic of tumors, and response to chemotherapy.
Carcinogenesis
Associations between single nucleotide polymorphisms in folate uptake and metabolizing genes with blood folate, homocysteine, and DNA uracil concentrations.
Carcinogenesis
Distribution of p53, GST, and MTHFR polymorphisms and risk of cervical intraepithelial lesions in sicily.
Carcinogenesis
Emerging Role of Polymorphisms of the MTHFR Gene in Systemic Carcinogenesis Besides Their Role in Migraines.
Carcinogenesis
Folate levels in mucosal tissue but not methylenetetrahydrofolate reductase polymorphisms are associated with gastric carcinogenesis.
Carcinogenesis
Folate metabolism-related gene polymorphisms and susceptibility to primary liver cancer in North China.
Carcinogenesis
Folic acid, polymorphism of methyl-group metabolism genes, and DNA methylation in relation to GI carcinogenesis.
Carcinogenesis
Genetic polymorphisms of methylenetetrahydrofolate reductase and aldehyde dehydrogenase 2, alcohol use and risk of colorectal adenomas: Self-Defense Forces Health Study.
Carcinogenesis
Genetic polymorphisms of methylenetetrahydrofolate reductase and promoter methylation of MGMT and FHIT genes in diffuse large B cell lymphoma risk in Middle East.
Carcinogenesis
Genetic polymorphisms of the methylenetetrahydrofolate reductase gene, plasma folate levels and breast cancer susceptibility: a case-control study in Taiwan.
Carcinogenesis
Impact of methylenetetrahydrofolate reductase (MTHFR) codon (677) and methionine synthase (MS) codon (2756) on risk of cervical carcinogenesis in North Indian population.
Carcinogenesis
Impact of the MTHFR C677T polymorphism on colorectal cancer in a population with low genetic variability.
Carcinogenesis
Low dietary folate initiates intestinal tumors in mice, with altered expression of G2-M checkpoint regulators polo-like kinase 1 and cell division cycle 25c.
Carcinogenesis
Meta- and pooled analyses of the methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and gastric cancer risk: a huge-GSEC review.
Carcinogenesis
Meta-analyses of the methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and risk of head and neck and lung cancer.
Carcinogenesis
Methylenetetrahydrofolate reductase (MTHFR) genotype, smoking habit, metastasis and oral cancer in Taiwan.
Carcinogenesis
Methylenetetrahydrofolate reductase 677 C-->T polymorphism and risk of proximal colon cancer in north Italy.
Carcinogenesis
Methylenetetrahydrofolate Reductase C677T Polymorphism and Cervical Cancer Risk: a Meta-Analysis.
Carcinogenesis
Methylenetetrahydrofolate reductase deficiency and low dietary folate reduce tumorigenesis in Apc min/+ mice.
Carcinogenesis
Methylenetetrahydrofolate reductase gene polymorphisms and lung cancer: a meta-analysis.
Carcinogenesis
Methylenetetrahydrofolate reductase gene polymorphisms association with the risk of diffuse large B cell lymphoma: a meta-analysis.
Carcinogenesis
Methylenetetrahydrofolate reductase gene polymorphisms association with the risk of follicular lymphoma: a meta-analysis.
Carcinogenesis
Methylenetetrahydrofolate reductase genotype does not play a role in multiple myeloma pathogenesis.
Carcinogenesis
Methylenetetrahydrofolate reductase polymorphism and minor increase of risk for oral cancer.
Carcinogenesis
Methylenetetrahydrofolate reductase polymorphism and risk of colorectal adenomas.
Carcinogenesis
Methylenetetrahydrofolate reductase polymorphism, dietary interactions, and risk of colorectal cancer.
Carcinogenesis
Methylenetetrahydrofolate reductase polymorphisms increase risk of esophageal squamous cell carcinoma in a Chinese population.
Carcinogenesis
Methylenetetrahydrofolate reductase polymorphisms, folate, and cancer risk: a paradigm of gene-nutrient interactions in carcinogenesis.
Carcinogenesis
MTHFR 677CC/1298CC genotypes are highly associated with chronic myelogenous leukemia: a case-control study in Korea.
Carcinogenesis
MTHFR A1298C and C677T gene polymorphisms and susceptibility to chronic myeloid leukemia in Egypt.
Carcinogenesis
MTHFR C677T and A1298C polymorphisms were associated with bladder cancer risk and disease progression: a meta-analysis.
Carcinogenesis
MTHFR C677T polymorphism and anatomopathological characteristics with prognostic significance in sporadic colorectal cancer.
Carcinogenesis
MTHFR C677T polymorphism contributes to colorectal cancer susceptibility: evidence from 61 case-control studies.
Carcinogenesis
MTHFR C677T polymorphisms and childhood acute lymphoblastic leukemia: A meta-analysis.
Carcinogenesis
MTHFR Knockdown Assists Cell Defense against Folate Depletion Induced Chromosome Segregation and Uracil Misincorporation in DNA.
Carcinogenesis
MTHFR polymorphism, methyl-replete diets and the risk of colorectal carcinoma and adenoma among U.S. men and women: an example of gene-environment interactions in colorectal tumorigenesis.
Carcinogenesis
MTHFR Polymorphisms and Opisthorchis viverrini Infection: a Relationship with Increased Susceptibility to Cholangiocarcinoma in Thailand.
Carcinogenesis
Pancreaticobiliary cancers with deficient methylenetetrahydrofolate reductase genotypes.
Carcinogenesis
Polymorphism of methylenetetrahydrofolate reductase (MTHFR) gene and risk of head and neck squamous cell carcinoma.
Carcinogenesis
Polymorphisms in one-carbon metabolism pathway genes, urinary arsenic profile, and urothelial carcinoma.
Carcinogenesis
Polymorphisms of 5,10-methylenetetrahydrofolate reductase and risk of gastric cancer in a Chinese population: a case-control study.
Carcinogenesis
Polymorphisms of methylenetetrahydrofolate reductase and methionine synthase genes and bladder cancer risk: a case-control study with meta-analysis.
Carcinogenesis
Polymorphisms of methylenetetrahydrofolate reductase are associated with a high risk of nasopharyngeal carcinoma in a smoking population from Southern China.
Carcinogenesis
Positive association between MTHFR C677T polymorphism and oral cancer risk: a meta-analysis.
Carcinogenesis
Quantitative proteomics reveals differentially expressed proteins in murine preneoplastic intestine in a model of intestinal tumorigenesis induced by low dietary folate and MTHFR deficiency.
Carcinogenesis
Relationship between the Methylation of Folic Acid Metabolism-Related Genes and the Incidence and Prognosis of Esophageal Cancer among Ethnic Kazakhs.
Carcinogenesis
Role of epigenetic and miR-22 and miR-29b alterations in the downregulation of Mat1a and Mthfr genes in early preneoplastic livers in rats induced by 2-acetylaminofluorene.
Carcinogenesis
Role of MTHFR C677T polymorphism in systemic carcinogenesis, besides its role in the pathogenesis of colo-rectal carcinomas.
Carcinogenesis
Role of MTHFR polymorphisms and folate levels in different phenotypes of sporadic colorectal cancers.
Carcinogenesis
Susceptibility to gastric cardia adenocarcinoma and genetic polymorphisms in methylenetetrahydrofolate reductase in an at-risk Chinese population.
Carcinogenesis
The effect of methylenetetrahydrofolate reductase polymorphism C677T on cervical cancer in Korean women.
Carcinogenesis
The methylenetetrahydrofolate reductase (MTHFR) C677T gene polymorphism is associated with breast cancer subtype susceptibility in southwestern China.
Carcinogenesis
The MTHFR 1298A>C polymorphism and genomic DNA methylation in human lymphocytes.
Carcinogenesis
The polymorphism of methylenetetrahydrofolate reductase C677T but not A1298C contributes to gastric cancer.
Carcinogenesis
Tyms double (2R) and triple repeat (3R) confers risk for human oral squamous cell carcinoma.
Carcinogenesis
[No association between MTHFR 677C>T polymorphism and ovarian cancer risk in BRCA1 mutation carriers in Wielkopolska region].
Carcinogenesis
[Single nucleotide polymorphisms in methylenetetrahydrofolate reductase gene and susceptibility to cancer of the gastric cardia in Chinese population]
Carcinoma
Aberrant DNA Methylation associated with MTHFR C677T Genetic Polymorphism in cutaneous squamous cell carcinoma in renal transplant patients.
Carcinoma
Aberrant DNA methylation of P16, MGMT, and hMLH1 genes in combination with MTHFR C677T genetic polymorphism and folate intake in esophageal squamous cell carcinoma.
Carcinoma
Aberrant DNA methylation of P16, MGMT, and hMLH1 genes in combination with MTHFR C677T genetic polymorphism in esophageal squamous cell carcinoma.
Carcinoma
Aberrant methylated key genes of methyl group metabolism within the molecular etiology of urothelial carcinogenesis.
Carcinoma
Allelic variations in 5, 10-methylenetetrahydrofolate reductase gene and susceptibility to cervical cancer in Indian women.
Carcinoma
An enhanced risk of basal cell carcinoma is associated with particular polymorphisms in the VDR and MTHFR genes.
Carcinoma
Analysis of relation between C677T genotype in MTHFR gene and prostatic cancer in Iranian males.
Carcinoma
Antisense inhibition of methylenetetrahydrofolate reductase reduces survival of methionine-dependent tumour lines.
Carcinoma
Application of microarray-based method for methylenetetrahydrofolate reductase (MTHFR) polymorphisms in the risk of gastric carcinoma in east China population.
Carcinoma
Association between a microRNA-214 binding site polymorphism in the methylenetetrahydrofolate reductase gene and esophageal squamous cell carcinoma.
Carcinoma
Association between dietary folate intake and clinical outcome in head and neck squamous cell carcinoma.
Carcinoma
Association between methylenetetrahydrofolate reductase polymorphisms, alcohol intake and oropharyngolaryngeal carcinoma in northern Italy.
Carcinoma
Association of methylenetetrahydrofolate reductase C677T-A1298C polymorphisms with risk for esophageal adenocarcinoma, Barrett's esophagus, and reflux esophagitis.
Carcinoma
Association of methylenetetrahydrofolate reductase polymorphism and the risk of squamous cell carcinoma in renal transplant patients.
Carcinoma
Association of Methylenetetrahydrofolate Reductase, Vitamin D Receptor, and Interleukin-16 Gene Polymorphisms With Renal Cell Carcinoma Risk.
Carcinoma
Association of the polymorphisms of MTHFR C677T, VDR C352T, and MPO G463A with risk for esophageal squamous cell dysplasia and carcinoma.
Carcinoma
Cancer-testis gene expression is associated with the methylenetetrahydrofolate reductase 677 C>T polymorphism in non-small cell lung carcinoma.
Carcinoma
Clinicopathologic features and genetic alterations in endometrioid carcinoma of the uterus with villoglandular differentiation.
Carcinoma
Diet folate, DNA methylation and genetic polymorphisms of MTHFR C677T in association with the prognosis of esophageal squamous cell carcinoma.
Carcinoma
Expression and clinical significance of methylenetetrahydrofolate reductase in patients with colorectal cancer.
Carcinoma
Folate intake, methylenetetrahydrofolate reductase polymorphisms in association with the prognosis of esophageal squamous cell carcinoma.
Carcinoma
Folate intake, MTHFR polymorphisms, and risk of esophageal, gastric, and pancreatic cancer: a meta-analysis.
Carcinoma
Gender-specific association of methylenetetrahydrofolate reductase genotype and haplotype with the aggressiveness and prognosis of clear cell renal cell carcinoma in Japanese patients.
Carcinoma
Genetic polymorphisms and susceptibility to esophageal cancer among Chinese population (review).
Carcinoma
Genetic polymorphisms in folate- metabolizing enzymes and risk of gastroesophageal cancers: a potential nutrient-gene interaction in cancer development.
Carcinoma
Genetic susceptibility of methylenetetrahydrofolate reductase (MTHFR) gene C677T, A1298C, and G1793A polymorphisms with risk for bladder transitional cell carcinoma in men.
Carcinoma
Genetic Variants in MTHFR Gene Predict ? 2 Radiation Pneumonitis in Esophageal Squamous Cell Carcinoma Patients Treated with Thoracic Radiotherapy.
Carcinoma
Genetic variations in MTHFR and esophageal squamous cell carcinoma susceptibility in Chinese Han population.
Carcinoma
Head and neck cancer susceptibility: a genetic marker in the methylenetetrahydrofolate reductase gene.
Carcinoma
Impact of one-carbon metabolism-related gene polymorphisms on risk of lung cancer in Japan: a case control study.
Carcinoma
In human alleles specific variation of MTHFR C677T and A1298C associated "risk factor" for the development of ovarian cancer.
Carcinoma
Influence of methylenetetrahydrofolate reductase polymorphisms in oral cancer patients.
Carcinoma
Loss of heterozygosity of methylenetetrahydrofolate reductase in colon carcinomas.
Carcinoma
Methyl group metabolism gene polymorphisms and susceptibility to prostatic carcinoma.
Carcinoma
Methylenetetrahydrofolate Reductase (MTHFR) Gene C677T, A1298C and G1793A Polymorphisms: Association with Risk for Clear Cell Renal Cell Carcinoma and Tumour Behaviour in Men.
Carcinoma
Methylenetetrahydrofolate reductase C677T and A1298C gene polymorphisms in oral squamous cell carcinoma in south-east Iran.
Carcinoma
Methylenetetrahydrofolate reductase C677T polymorphism and predisposition towards esophageal squamous cell carcinoma in a German Caucasian and a northern Chinese population.
Carcinoma
Methylenetetrahydrofolate reductase gene polymorphisms and the risk of colorectal carcinoma in a sample of Egyptian individuals.
Carcinoma
Methylenetetrahydrofolate Reductase Genetic Polymorphisms and Esophageal Squamous Cell Carcinoma Susceptibility: A Meta-analysis of Case-control Studies.
Carcinoma
Methylenetetrahydrofolate reductase genetic polymorphisms and esophageal squamous cell carcinoma susceptibility: A meta-analysis of case-control studies.
Carcinoma
Methylenetetrahydrofolate reductase polymorphisms and risk of squamous cell carcinoma of the head and neck: a case-control analysis.
Carcinoma
Methylenetetrahydrofolate reductase polymorphisms increase risk of esophageal squamous cell carcinoma in a Chinese population.
Carcinoma
MTHFR C677T and A1298C polymorphisms and cervical carcinoma susceptibility: meta-analyses based on 4421 individuals.
Carcinoma
MTHFR C677T and A1298C polymorphisms as predictors of radiotherapy response in head and neck squamous cell carcinoma.
Carcinoma
MTHFR C677T genetic polymorphism in combination with serum vitamin B2, B12 and aberrant DNA methylation of P16 and P53 genes in esophageal squamous cell carcinoma and esophageal precancerous lesions: a case-control study.
Carcinoma
MTHFR C677T polymorphism interaction with heavy alcohol consumption increases head and neck carcinoma risk.
Carcinoma
MTHFR C677T polymorphisms are associated with aberrant methylation of the IGF-2 gene in transitional cell carcinoma of the bladder.
Carcinoma
Polymorphic methyl group metabolism genes in patients with transitional cell carcinoma of the urinary bladder.
Carcinoma
Polymorphism of methylenetetrahydrofolate reductase (MTHFR) gene and risk of head and neck squamous cell carcinoma.
Carcinoma
Polymorphisms and haplotypes in methylenetetrahydrofolate reductase gene and head and neck squamous cell carcinoma risk.
Carcinoma
Polymorphisms of MTHFR and susceptibility to oesophageal adenocarcinoma in a Caucasian United Kingdom population.
Carcinoma
Polymorphisms of MTHFR C677T and A1298C association with oral carcinoma risk: a meta-analysis.
Carcinoma
Prediction of response to neoadjuvant chemotherapy in carcinomas of the upper gastrointestinal tract.
Carcinoma
Quantitative assessment of the effect of MTHFR polymorphisms on the risk of lung carcinoma.
Carcinoma
Relationships among MTHFR a1298c gene polymorphisms and methylation status of Dact1 gene in transitional cell carcinomas.
Carcinoma
Renal cell carcinoma risk is associated with the interactions of APOE, VHL and MTHFR gene polymorphisms.
Carcinoma
Role of MTHFR C677T polymorphism in systemic carcinogenesis, besides its role in the pathogenesis of colo-rectal carcinomas.
Carcinoma
Serum folate, MTHFR C677T polymorphism and esophageal squamous cell carcinoma risk.
Carcinoma
Smoking and polymorphisms in folate metabolizing genes and their effects on the histological stage and grade for bladder tumors.
Carcinoma
Systematic Review on the Relationship between Genetic Polymorphisms of Methylenetetrahydrofolate Reductase and Esophageal Squamous Cell Carcinoma.
Carcinoma
The association between MTHFR gene polymorphisms (C677T, A1298C) and oral squamous cell carcinoma: A systematic review and meta-analysis.
Carcinoma
The combination of methylenehydrofolate reductase C677T polymorphism screening and gastrointestinal tumor markers detection may be an early screening method for gastrointestinal cancer related to helicobacter pylori infection.
Carcinoma
The methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and cancer risk: the Croatian case-control study.
Carcinoma
[Association between genetic polymorphisms in methylenetetrahydrofolate reductase and risk of laryngeal squamous cell carcinoma]
Carcinoma
[Correlation of aberrant methylation of MGMT gene to MTHFR C677T genetic polymorphisms in esophageal squamous cell carcinoma]
Carcinoma
[Relationship of methylenetetrahydrofolate reductase C677T polymorphism and chemosensitivity to 5-fluorouracil in gastric carcinoma]
Carcinoma, Basal Cell
An enhanced risk of basal cell carcinoma is associated with particular polymorphisms in the VDR and MTHFR genes.
Carcinoma, Ehrlich Tumor
The NADP-dependent trifunctional methylenetetrahydrofolate dehydrogenase purified from mouse liver is immunologically distinct from the mouse NAD-dependent [corrected] bifunctional enzyme.
Carcinoma, Hepatocellular
Association between methylenetetrahydrofolate reductase tagging polymorphisms and susceptibility of hepatocellular carcinoma: a case-control study.
Carcinoma, Hepatocellular
Association between MTHFR A1298C polymorphism and hepatocellular carcinoma risk.
Carcinoma, Hepatocellular
Association between the methylenetetrahydrofolate reductase C677T polymorphism and hepatocellular carcinoma risk: a meta-analysis.
Carcinoma, Hepatocellular
Associations between methylenetetrahydrofolate reductase polymorphisms and hepatocellular carcinoma risk in Chinese population.
Carcinoma, Hepatocellular
Correlation between Methylenetetrahydrofolate Reductase Polymorphisms and Hepatocellular Carcinoma: A Meta-Analysis.
Carcinoma, Hepatocellular
Correlation Between MTHFR Polymorphisms and Hepatocellular Carcinoma: A Meta-analysis.
Carcinoma, Hepatocellular
Genetic Polymorphism of MTHFR C677T Influences Susceptibility to HBV-Related Hepatocellular Carcinoma in a Chinese Population: a Case-Control Study.
Carcinoma, Hepatocellular
Genetic polymorphisms in the methylenetetrahydrofolate reductase and thymidylate synthase genes and risk of hepatocellular carcinoma.
Carcinoma, Hepatocellular
Meta-analysis of MTHFR C677T and A1298C gene polymorphisms: Association with the risk of hepatocellular carcinoma.
Carcinoma, Hepatocellular
Methylenetetrahydrofolate reductase (MTHFR) and methionine synthase reductase (MTRR) gene polymorphisms as risk factors for hepatocellular carcinoma in a Korean population.
Carcinoma, Hepatocellular
Methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms and the risk of primary hepatocellular carcinoma (HCC) in a Chinese population.
Carcinoma, Hepatocellular
Methylenetetrahydrofolate reductase C677T (Ala>Val, rs1801133 C>T) polymorphism decreases the susceptibility of hepatocellular carcinoma: a meta-analysis involving 12,628 subjects.
Carcinoma, Hepatocellular
MTHFR C677T polymorphism and risk of HCC in patients with liver cirrhosis: role of male gender and alcohol consumption.
Carcinoma, Hepatocellular
MTHFR C677TT, PAI1 4G-4G, V Leiden Q506, and prothrombin G20210A in hepatocellular carcinoma with and without portal vein thrombosis.
Carcinoma, Hepatocellular
MTHFR Knockdown Assists Cell Defense against Folate Depletion Induced Chromosome Segregation and Uracil Misincorporation in DNA.
Carcinoma, Hepatocellular
Significant association between MTHFR C677T polymorphism and hepatocellular carcinoma risk: a meta-analysis.
Carcinoma, Hepatocellular
Significant association between the MTHFR A1298C polymorphism and hepatocellular carcinoma risk: a meta-analysis.
Carcinoma, Hepatocellular
The Association between MTHFR Gene Polymorphisms and Hepatocellular Carcinoma Risk: A Meta-Analysis.
Carcinoma, Hepatocellular
The MTHFR 677C > T polymorphism is associated with an increased risk of hepatocellular carcinoma in patients with alcoholic cirrhosis.
Carcinoma, Hepatocellular
The MTHFR polymorphism affect the susceptibility of HCC and the prognosis of HCC liver transplantation.
Carcinoma, Hepatocellular
[A study on the association of MTHFR C677T polymorphism with genetic susceptibility to hepatocellular carcinoma.]
Carcinoma, Non-Small-Cell Lung
Cancer-testis gene expression is associated with the methylenetetrahydrofolate reductase 677 C>T polymorphism in non-small cell lung carcinoma.
Carcinoma, Non-Small-Cell Lung
Correlation Between Methylenetetrahydrofolate Reductase (MTHFR) C677T Polymorphisms and Pemetrexed Chemotherapy Efficacy/Toxicity in Non-Squamous Non-Small Cell Lung Cancer.
Carcinoma, Non-Small-Cell Lung
Heterozygote advantage of methylenetetrahydrofolate reductase polymorphisms on clinical outcomes in advanced non-small cell lung cancer (NSCLC) patients treated with platinum-based chemotherapy.
Carcinoma, Non-Small-Cell Lung
Hierarchical clustering of lung cancer cell lines using DNA methylation markers.
Carcinoma, Non-Small-Cell Lung
Influence of methylenetetrahydrofolate reductase C677T polymorphism on the risk of lung cancer and the clinical response to platinum-based chemotherapy for advanced non-small cell lung cancer: an updated meta-analysis.
Carcinoma, Non-Small-Cell Lung
Methylenetetrahydrofolate reductase C677T polymorphism predicts response and time to progression to gemcitabine-based chemotherapy for advanced non-small cell lung cancer in a Chinese Han population.
Carcinoma, Non-Small-Cell Lung
Methylenetetrahydrofolate reductase gene C677T and A1298C polymorphisms in patients with small cell and non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
Pharmacogenetics in cancer therapy - 8 years of experience at the Institute for Oncology and Radiology of Serbia.
Carcinoma, Non-Small-Cell Lung
Polymorphisms in thymidylate synthase and reduced folate carrier (SLC19A1) genes predict survival outcome in advanced non-small cell lung cancer patients treated with pemetrexed-based chemotherapy.
Carcinoma, Non-Small-Cell Lung
[Genetic polymorphisms in methylenetetrahydrofolate reductase and clinical response to chemotherapy in non-small cell lung cancer.]
Carcinoma, Renal Cell
Association of Methylenetetrahydrofolate Reductase, Vitamin D Receptor, and Interleukin-16 Gene Polymorphisms With Renal Cell Carcinoma Risk.
Carcinoma, Renal Cell
Gender-specific association of methylenetetrahydrofolate reductase genotype and haplotype with the aggressiveness and prognosis of clear cell renal cell carcinoma in Japanese patients.
Carcinoma, Renal Cell
Methylenetetrahydrofolate Reductase (MTHFR) Gene C677T, A1298C and G1793A Polymorphisms: Association with Risk for Clear Cell Renal Cell Carcinoma and Tumour Behaviour in Men.
Carcinoma, Renal Cell
Renal cell carcinoma risk is associated with the interactions of APOE, VHL and MTHFR gene polymorphisms.
Carcinoma, Squamous Cell
Aberrant DNA Methylation associated with MTHFR C677T Genetic Polymorphism in cutaneous squamous cell carcinoma in renal transplant patients.
Carcinoma, Squamous Cell
Allelic variations in 5, 10-methylenetetrahydrofolate reductase gene and susceptibility to cervical cancer in Indian women.
Carcinoma, Squamous Cell
Association between dietary folate intake and clinical outcome in head and neck squamous cell carcinoma.
Carcinoma, Squamous Cell
Association of methylenetetrahydrofolate reductase polymorphism and the risk of squamous cell carcinoma in renal transplant patients.
Carcinoma, Squamous Cell
Head and neck cancer susceptibility: a genetic marker in the methylenetetrahydrofolate reductase gene.
Carcinoma, Squamous Cell
Meta-analysis on MTHFR polymorphism and lung cancer susceptibility in East Asian populations.
Carcinoma, Squamous Cell
Methylenetetrahydrofolate reductase polymorphisms and risk of squamous cell carcinoma of the head and neck: a case-control analysis.
Carcinoma, Squamous Cell
MTHFR C677T and A1298C polymorphisms as predictors of radiotherapy response in head and neck squamous cell carcinoma.
Carcinoma, Squamous Cell
Polymorphism of methylenetetrahydrofolate reductase (MTHFR) gene and risk of head and neck squamous cell carcinoma.
Carcinoma, Squamous Cell
Polymorphisms and haplotypes in methylenetetrahydrofolate reductase gene and head and neck squamous cell carcinoma risk.
Carcinoma, Transitional Cell
Genetic susceptibility of methylenetetrahydrofolate reductase (MTHFR) gene C677T, A1298C, and G1793A polymorphisms with risk for bladder transitional cell carcinoma in men.
Carcinoma, Transitional Cell
MTHFR C677T polymorphisms are associated with aberrant methylation of the IGF-2 gene in transitional cell carcinoma of the bladder.
Carcinoma, Transitional Cell
Polymorphic methyl group metabolism genes in patients with transitional cell carcinoma of the urinary bladder.
Carcinoma, Transitional Cell
Relationships among MTHFR a1298c gene polymorphisms and methylation status of Dact1 gene in transitional cell carcinomas.
Cardiomyopathy, Hypertrophic
Prevalence and clinical implications of hyperhomocysteinaemia in patients with hypertrophic cardiomyopathy and MTHFR C6777T polymorphism.
Cardiovascular Diseases
A common mutation in the methylenetetrahydrofolate reductase gene (C677T) increases the risk for deep-vein thrombosis in patients with mutant factor V (factor V:Q506).
Cardiovascular Diseases
A novel multiplex PCR-RFLP method for simultaneous detection of the MTHFR 677 C > T, eNOS +894 G > T and - eNOS -786 T > C variants among Malaysian Malays.
Cardiovascular Diseases
A plasma proteomics method reveals links between ischemic stroke and MTHFR C677T genotype.
Cardiovascular Diseases
A possible genetic link between MTHFR genotype and smoking behavior.
Cardiovascular Diseases
A second common variant in the methylenetetrahydrofolate reductase (MTHFR) gene and its relationship to MTHFR enzyme activity, homocysteine, and cardiovascular disease risk.
Cardiovascular Diseases
An association between the methylenetetrahydrofolate reductase (MTHFR) C677T mutation and inflammation markers related to cardiovascular disease.
Cardiovascular Diseases
An MTHFR variant, homocysteine, and cardiovascular comorbidity in renal disease.
Cardiovascular Diseases
Analysis of two mutations in the MTHFR gene associated with mild hyperhomocysteinaemia--heterogeneous distribution in the South African population.
Cardiovascular Diseases
Antiepileptic drugs, hyperhomocysteinemia and B-vitamins supplementation in patients with epilepsy.
Cardiovascular Diseases
Apolipoprotein E and methylenetetrahydrofolate reductase genetic polymorphisms in relation to other risk factors for cardiovascular disease in UK Caucasians and Black South Africans.
Cardiovascular Diseases
Are the methylenetetrahydrofolate reductase 1298 and 677 gene polymorphisms related to optic glioma and hamartoma risk in neurofibromatosis type 1 patients?
Cardiovascular Diseases
Association between polymorphism of MTHFR c.677C>T and risk of cardiovascular disease in Turkish population: a meta-analysis for 2.780 cases and 3.022 controls.
Cardiovascular Diseases
Association of Methylenetetrahydrofolate Reductase C677T and Cystathionine β-Synthase Polymorphisms in Cardiovascular Disease in the Algerian Population.
Cardiovascular Diseases
Association of methylenetetrahydrofolate reductase gene (C677T) with the risk of hypertension in Morocco.
Cardiovascular Diseases
Association of serum VLDL level with hyperhomocysteinemia in hypertensive patients: A cross-sectional study.
Cardiovascular Diseases
Atherosclerosis in male patients with ankylosing spondylitis: the relation with methylenetetrahydrofolate reductase (C677T) gene polymorphism and plasma homocysteine levels.
Cardiovascular Diseases
Blood pressure in treated hypertensive individuals with the MTHFR 677TT genotype is responsive to intervention with riboflavin: findings of a targeted randomized trial.
Cardiovascular Diseases
C677T polymorphism in methylenetetrahydrofolate reductase gene and psychoses.
Cardiovascular Diseases
C677T polymorphism of the MTHFR gene and variant hemoglobins: a study in newborns from Salvador, Bahia, Brazil.
Cardiovascular Diseases
Cardiometabolic risk and the MTHFR C677T variant in children treated with second-generation antipsychotics.
Cardiovascular Diseases
Characterization of a pseudogene for murine methylenetetrahydrofolate reductase.
Cardiovascular Diseases
Common mutation in the methylenetetrahydrofolate reductase gene offers no support for mild hyperhomocysteinemia being a causal risk factor for cardiovascular disease.
Cardiovascular Diseases
Comparison of Capillary Electrophoresis, AGE, and PAGE for MTHFR Polymorphism Analysis in FFPE Cervical Samples.
Cardiovascular Diseases
Correlations of MTHFR 677C>T polymorphism with cardiovascular disease in patients with end-stage renal disease: a meta-analysis.
Cardiovascular Diseases
Does the MTHFR C677T gene polymorphism indicate cardiovascular disease risk in type 2 diabetes mellitus patients?
Cardiovascular Diseases
Elevated plasma homocysteine is positively associated with age independent of C677T mutation of the methylenetetrahydrofolate reductase gene in selected Egyptian subjects.
Cardiovascular Diseases
Endothelial nitric oxide synthase and methylenetetrahydrofolate reductase gene polymorphisms are associated with endothelial dysfunction in young, healthy men.
Cardiovascular Diseases
Endothelial nitric oxide synthetase, methylenetetrahydrofolate reductase polymorphisms, and cardiovascular complications in Tunisian patients with nondiabetic renal disease.
Cardiovascular Diseases
Epigenetics in Clinical Practice: Characterizing Patient and Provider Experiences with MTHFR Polymorphisms and Methylfolate.
Cardiovascular Diseases
Evaluation of Factor V G1691A, prothrombin G20210A, Factor XIII V34L, MTHFR A1298C, MTHFR C677T and PAI-1 4G/5G genotype frequencies of patients subjected to cardiovascular disease (CVD) panel in south-east region of Turkey.
Cardiovascular Diseases
Fasting, postprandial, and post-methionine-load homocysteinaemia and methylenetetrahydrofolate reductase polymorphism in vascular disease.
Cardiovascular Diseases
Folate network genetic variation predicts cardiovascular disease risk in non-Hispanic white males.
Cardiovascular Diseases
Frequency of methylenetetrahydrofolate reductase C677T polymorphism in patients with cardiovascular disease in Eastern Saudi Arabia.
Cardiovascular Diseases
Functional Polymorphism rs13306560 of the MTHFR Gene Is Associated With Essential Hypertension in a Mexican-Mestizo Population.
Cardiovascular Diseases
Genetic and Metabolite Variability in One-Carbon Metabolism Applied to an Insulin Resistance Model in Patients With Schizophrenia Receiving Atypical Antipsychotics.
Cardiovascular Diseases
Genetic factors associated with the absence of atherosclerosis in octogenarians.
Cardiovascular Diseases
Genetic polymorphism of methylenetetrahydrofolate reductase and myocardial infarction. A case-control study.
Cardiovascular Diseases
Head and neck cancer susceptibility: a genetic marker in the methylenetetrahydrofolate reductase gene.
Cardiovascular Diseases
Homocysteine, folate, lipid profile and MTHFR genotype and disability in children with myelomeningocele.
Cardiovascular Diseases
Implications on human fertility of the 677C-->T and 1298A-->C polymorphisms of the MTHFR gene: consequences of a possible genetic selection.
Cardiovascular Diseases
Influence of methylenetetrahydrofolate reductase genotype, exercise and other risk factors on endothelial function in healthy individuals.
Cardiovascular Diseases
Influence of MTHFR C677T gene polymorphism in the development of cardiovascular disease in Egyptian patients with rheumatoid arthritis.
Cardiovascular Diseases
Insights on the structural perturbations in human MTHFR Ala222Val mutant by protein modeling and molecular dynamics.
Cardiovascular Diseases
Interactions between the single nucleotide polymorphisms in the homocysteine pathway (MTHFR 677C>T, MTHFR 1298 A>C, and CBSins) and the efficacy of HMG-CoA reductase inhibitors in preventing cardiovascular disease in high-risk patients of hypertension: the GenHAT study.
Cardiovascular Diseases
Interrelationships among the MTHFR 677C>T polymorphism, migraine, and cardiovascular disease.
Cardiovascular Diseases
Meta-analysis study to evaluate the association of MTHFR C677T polymorphism with risk of ischemic stroke.
Cardiovascular Diseases
Metabolic syndrome and insulin resistance in schizophrenia patients receiving antipsychotics genotyped for the methylenetetrahydrofolate reductase (MTHFR) 677C/T and 1298A/C variants.
Cardiovascular Diseases
Methylene tetrahydrofolate reductase (MTHFR) and nitric oxide synthase (ecNOS) genes and risks of peripheral arterial disease and coronary heart disease: Edinburgh Artery Study.
Cardiovascular Diseases
Methylenetetrahydrofolate reductase (MTHFR) deficiency enhances resistance against cytomegalovirus infection.
Cardiovascular Diseases
Methylenetetrahydrofolate reductase 677 C/T genotype and cardiovascular disease mortality in postmenopausal women.
Cardiovascular Diseases
Methylenetetrahydrofolate reductase 677C->T polymorphism and folate status affect one-carbon incorporation into human DNA deoxynucleosides.
Cardiovascular Diseases
Methylenetetrahydrofolate reductase C677T and methionine synthase A2756G gene polymorphisms and associated risk of cardiovascular diseases: A study from Jammu region.
Cardiovascular Diseases
METHYLENETETRAHYDROFOLATE REDUCTASE C677T POLYMORPHISM IN PATIENTS WITH HENOCH-SCHÖNLEIN PURPURA.
Cardiovascular Diseases
Methylenetetrahydrofolate reductase gene C677T and A1298C polymorphisms and susceptibility to recurrent pregnancy loss.
Cardiovascular Diseases
Methylenetetrahydrofolate reductase gene polymorphism, hyperhomocysteinemia, and cardiovascular diseases in chronic hemodialysis patients.
Cardiovascular Diseases
Methylenetetrahydrofolate reductase polymorphism (C677T), hyperhomocysteinemia, and risk of ischemic cardiovascular disease and venous thromboembolism: prospective and case-control studies from the Copenhagen City Heart Study.
Cardiovascular Diseases
Methylenetetrahydrofolate reductase polymorphism determines the plasma homocysteine-lowering effect of large-dose folic acid supplementation in patients with cardiovascular disease.
Cardiovascular Diseases
Methylenetetrahydrofolate reductase TT genotype as a predictor of cardiovascular risk in hypertensive adolescents.
Cardiovascular Diseases
Methylenetetrahydrofolate reductase variants associated with hypertension and cardiovascular disease interact with dietary polyunsaturated Fatty acids to modulate plasma homocysteine in puerto rican adults.
Cardiovascular Diseases
Microarray analysis of brain RNA in mice with methylenetetrahydrofolate reductase deficiency and hyperhomocysteinemia.
Cardiovascular Diseases
Molecular beacons: a new approach for semiautomated mutation analysis.
Cardiovascular Diseases
Molecular genetic analysis in mild hyperhomocysteinemia: a common mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for cardiovascular disease.
Cardiovascular Diseases
Molecular phylogenetic analysis of methylenetetrahydrofolate reductase family of proteins.
Cardiovascular Diseases
MTHFR 677C-->T mutation, folate intake, neural-tube defect, and risk of cardiovascular disease.
Cardiovascular Diseases
MTHFR A1298C polymorphism is associated with cardiovascular risk in end stage renal disease in North Indians.
Cardiovascular Diseases
MTHFR C677T genotype and cardiovascular risk in a general population without mandatory folic acid fortification.
Cardiovascular Diseases
MTHFR Gene variants C677T, A1298C and association with Down syndrome: A Case-control study from South India.
Cardiovascular Diseases
Multiple transcription start sites and alternative splicing in the methylenetetrahydrofolate reductase gene result in two enzyme isoforms.
Cardiovascular Diseases
Mutational landscape screening of methylene tetrahydrofolate reductase to predict homocystinuria associated variants: An integrative computational approach.
Cardiovascular Diseases
Oxidative stress and platelet activation in subjects with moderate hyperhomocysteinaemia due to MTHFR 677 C ?T polymorphism.
Cardiovascular Diseases
Polymorphism in methylenetetrahydrofolate reductase gene: its impact on plasma homocysteine levels and carotid atherosclerosis in ESRD patients receiving hemodialysis.
Cardiovascular Diseases
Polymorphisms in cytoplasmic serine hydroxymethyltransferase and methylenetetrahydrofolate reductase affect the risk of cardiovascular disease in men.
Cardiovascular Diseases
Polymorphisms in serine hydroxymethyltransferase 1 and methylenetetrahydrofolate reductase interact to increase cardiovascular disease risk in humans.
Cardiovascular Diseases
Prospective study of methylenetetrahydrofolate reductase (MTHFR) variant C677T and risk of all-cause and cardiovascular disease mortality among 6000 US adults.
Cardiovascular Diseases
Recent data are not in conflict with homocysteine as a cardiovascular risk factor.
Cardiovascular Diseases
Resident Training on Methylenetetrahydrofolate Reductase: a National Survey.
Cardiovascular Diseases
Riboflavin lowers blood pressure in cardiovascular disease patients homozygous for the 677C-->T polymorphism in MTHFR.
Cardiovascular Diseases
Riboflavin offers a targeted strategy for managing hypertension in patients with the MTHFR 677TT genotype: a 4-y follow-up.
Cardiovascular Diseases
Risk factors associated with metabolic syndrome in bipolar and schizophrenia subjects treated with antipsychotics: the role of folate pharmacogenetics.
Cardiovascular Diseases
Role of a common mutation in the homocysteine regulatory enzyme methylenetetrahydrofolate reductase in ischemic stroke.
Cardiovascular Diseases
Role of inherited thrombophilic profile on survival of patients with sepsis.
Cardiovascular Diseases
Semiautomated DNA mutation analysis using a robotic workstation and molecular beacons.
Cardiovascular Diseases
Serum homocysteine, methylenetetrahydrofolate reductase gene polymorphism and cardiovascular disease in heterozygous familial hypercholesterolemia.
Cardiovascular Diseases
Serum levels of miR-199a-5p correlates with blood pressure in premature cardiovascular disease patients homozygous for the MTHFR 677C?>?T polymorphism.
Cardiovascular Diseases
Severe and mild mutations in cis for the methylenetetrahydrofolate reductase (MTHFR) gene, and description of five novel mutations in MTHFR.
Cardiovascular Diseases
Structural Perturbations in the Ala --> Val Polymorphism of Methylenetetrahydrofolate Reductase: How Binding of Folates May Protect against Inactivation(,).
Cardiovascular Diseases
Studying the association between methylenetetrahydrofolate reductase (MTHFR) 677 gene polymorphism, cardiovascular risk and lichen planus.
Cardiovascular Diseases
The A677V methylenetetrahydrofolate reductase gene polymorphism and carotid atherosclerosis.
Cardiovascular Diseases
The APOE E4 Allele Confers Increased Risk of Ischemic Stroke Among Greek Carriers.
Cardiovascular Diseases
The C677T methylenetetrahydrofolate reductase gene mutation does not influence cardiovascular risk in the dialysis population: results of a multicentre prospective study.
Cardiovascular Diseases
The C677T methylenetetrahydrofolate reductase polymorphism influences the homocysteine-lowering effect of hormone replacement therapy.
Cardiovascular Diseases
The common mutations C677T and A1298C in the human methylenetetrahydrofolate reductase gene are associated with hyperhomocysteinemia and cardiovascular disease in hemodialysis patients.
Cardiovascular Diseases
The effects of genetic polymorphisms and diabetes mellitus on the development of peripheral artery disease.
Cardiovascular Diseases
The methylenetetrahydrofolate reductase C677T gene mutation is associated with hyperhomocysteinemia, cardiovascular disease and plasma B-type natriuretic peptide levels in Korea.
Cardiovascular Diseases
The methylenetetrahydrofolate reductase gene is associated with increased cardiovascular risk in Japan, but not in other populations.
Cardiovascular Diseases
The Prevalence of Methylenetetrahydrofolate Reductase 677 C-T, Factor V 1691 G-A, and Prothrombin 20210 G-A Mutations in Healthy Populations in Setif, Algeria.
Cardiovascular Diseases
Thermolabile methylenetetrahydrofolate reductase polymorphism (C677T) and total homocysteine concentration among African-American and white women.
Cardiovascular Diseases
Thermolabile methylenetetrahydrofolate reductase, homocysteine, and cardiovascular disease risk: the European Concerted Action Project.
Cardiovascular Diseases
Total homocysteine, folate, and cobalamin, and their relation to genetic polymorphisms, lifestyle and body mass index in healthy children and adolescents.
Cardiovascular Diseases
Total plasma homocysteine is associated with hypertension in Type I diabetic patients.
Cardiovascular Diseases
Unique holoenzyme dimers of the tetrameric enzyme Escherichia coli methylenetetrahydrofolate reductase: characterization of structural features associated with modulation of the enzyme's function.
Cardiovascular Diseases
[Homocysteinemia and its relationship with the methylentetrahydrofolate reductase polymorphism in various ethnic groups from western Venezuela]
Cardiovascular Diseases
[Prevalence of methylenetetrahydrofolate reductase (MTHFR) gene polymorphism (C677T) in the Hungarian population]
Cardiovascular Diseases
[The plasma homocysteine, folic acid and vitamin B12 levels in young people with high risk for cardiovascular disease and its relation to metylentetrahydrofolate reductase (MTHFR) gene polymorphism]
Cardiovascular Diseases
[The role of homocysteine and methylenetetrahydrofolate reductase, methionine synthase, methionine synthase reductase polymorphisms in the development of cardiovascular diseases and hypertension].
Carotid Artery Diseases
An association of 5,10-methylenetetrahydrofolate reductase (MTHFR) gene polymorphism and common carotid atherosclerosis.
Carotid Artery Diseases
Association of methylenetetrahydrofolate reductase (MTHFR) variant C677T and risk of carotid atherosclerosis: a cross-sectional analysis of 730 Chinese Han adults in Chongqing.
Carotid Artery Diseases
Association of methylenetetrahydrofolate reductase gene polymorphism with carotid atherosclerosis depending on smoking status in a Japanese general population.
Carotid Artery Diseases
B-group vitamins, MTHFR C677T polymorphism and carotid intima-media thickness in clinically healthy subjects.
Carotid Artery Diseases
Genetic factors associated with the absence of atherosclerosis in octogenarians.
Carotid Artery Diseases
MTHFR A1298C polymorphism is associated with cardiovascular risk in end stage renal disease in North Indians.
Carotid Artery Diseases
Plasma homocyst(e)ine concentration, but not MTHFR genotype, is associated with variation in carotid plaque area.
Carotid Artery Diseases
Polymorphism in methylenetetrahydrofolate reductase gene: its impact on plasma homocysteine levels and carotid atherosclerosis in ESRD patients receiving hemodialysis.
Carotid Artery Diseases
The A677V methylenetetrahydrofolate reductase gene polymorphism and carotid atherosclerosis.
Carotid Artery Diseases
The A677V MTHFR allele is not associated with carotid atherosclerosis in octogenarians.
Carotid Artery Diseases
Thrombophilic risk factors in patients with severe carotid atherosclerosis.
Carotid Stenosis
A methylenetetrahydrofolate reductase gene polymorphism in ischaemic stroke and in carotid artery stenosis.
Carotid Stenosis
Association of methylenetetrahydrofolate reductase gene polymorphism with carotid atherosclerosis depending on smoking status in a Japanese general population.
Carotid Stenosis
Cerebrovascular events in patients with significant stenosis of the carotid artery are associated with hyperhomocysteinemia and platelet antigen-1 (Leu33Pro) polymorphism.
Carotid Stenosis
Polymorphism of apoprotein E (APOE), methylenetetrahydrofolate reductase (MTHFR) and paraoxonase (PON1) genes in patients with cerebrovascular disease.
Carotid Stenosis
Thrombophilic risk factors in patients with severe carotid atherosclerosis.
Cataract
Association of OGG1 and MTHFR polymorphisms with age-related cataract: A systematic review and meta-analysis.
Cataract
Associations Between Methylenetetrahydrofolate Reductase Polymorphisms, Serum Homocysteine Levels, and Incident Cortical Cataract.
Cataract
Associations of Polymorphisms in MTHFR Gene with the Risk of Age-Related Cataract in Chinese Han Population: A Genotype-Phenotype Analysis.
Cataract
C677T variant in the methylentetrahydrofolate reductase gene is a genetic risk factor for primary open-angle glaucoma.
Cataract
Methylenetetrahydrofolate reductase genetic polymorphisms in patients with cataract.
Celiac Disease
Effect of B vitamin supplementation on plasma homocysteine levels in celiac disease.
Cerebral Hemorrhage
Association of CVD candidate gene polymorphisms with ischemic stroke and cerebral hemorrhage in Chinese individuals.
Cerebral Hemorrhage
Evaluation of MTHFR C677T polymorphism in ischemic and hemorrhagic stroke patients. A case-control study in a Northern Indian population.
Cerebral Hemorrhage
Interaction between methylenetetrahydrofolate reductase C677T gene polymorphism and sleep duration on risk of stroke pathogenesis.
Cerebral Hemorrhage
Methylenetetrahydrofolate reductase gene polymorphism: relation to blood pressure and cerebrovascular disease.
Cerebral Hemorrhage
Methylenetetrahydrofolate Reductase Gene Polymorphisms (C677T and A1298C) and Hemorrhagic Stroke in Moroccan Patients.
Cerebral Hemorrhage
Methylenetetrahydrofolate reductase gene polymorphisms in patients with cerebral hemorrhage.
Cerebral Hemorrhage
The MTHFR C677T Polymorphism and Risk of Intracerebral Hemorrhage in a Chinese Han Population.
Cerebral Infarction
An analysis of methylenetetrahydrofolate reductase and glutathione S-transferase omega-1 genes as modifiers of the cerebral response to ischemia.
Cerebral Infarction
Association Between MTHFR Gene Polymorphisms, Smoking, and the Incidence of Vascular Dementia.
Cerebral Infarction
Association of plasma homocysteine level and N5,N10-methylenetetrahydrofolate reductase gene polymorphism with cerebral infarction.
Cerebral Infarction
Factor V1691 G-A, prothrombin 20210 G-A, and methylenetetrahydrofolate reductase 677 C-T variants in Turkish children with cerebral infarct.
Cerebral Infarction
Interaction between methylenetetrahydrofolate reductase C677T gene polymorphism and sleep duration on risk of stroke pathogenesis.
Cerebral Infarction
Methylenetetrahydrofolate reductase gene polymorphism and ischemic stroke in Japanese.
Cerebral Infarction
Methylenetetrahydrofolate reductase gene polymorphism: relation to blood pressure and cerebrovascular disease.
Cerebral Infarction
MTHFR homozygous mutation and additional risk factors for cerebral infarction in a large Italian family.
Cerebral Infarction
Pathogenicity of thermolabile methylenetetrahydrofolate reductase for vascular dementia.
Cerebral Infarction
Postoperative Symptomatic Cerebral Infarction in Pediatric Moyamoya Disease: Risk Factors and Clinical Outcome.
Cerebral Infarction
Prevalence of methylenetetrahydrofolate reductase C677T and its association with arterial and venous thrombosis in the Chinese population.
Cerebral Infarction
[Hyperhomocysteine, methylenetetrahydrofolate reductase gene, and other risk factors in ischemic stroke]
Cerebral Infarction
[Polimorfismos asociados a disfunción endotelial y a un estado protrombótico en jóvenes mexicanos con infarto cerebral].
Cerebral Palsy
Methylenetetrahydrofolate reductase gene polymorphisms and cerebral palsy in Chinese infants.
Cerebral Palsy
TNF-? and MTHFR Polymorphisms Associated with Cerebral Palsy in Chinese Infants.
Cerebral Small Vessel Diseases
Association of MTHFR C677T Genotype With Ischemic Stroke Is Confined to Cerebral Small Vessel Disease Subtype.
Cerebral Small Vessel Diseases
Single nucleotide polymorphism of MTHFR rs1801133 associated with elevated Hcy levels affects susceptibility to cerebral small vessel disease.
Cerebrovascular Disorders
A common polymorphism in the methylenetetrahydrofolate reductase gene, homocysteine, and ischemic cerebrovascular disease.
Cerebrovascular Disorders
Association of homocysteine (but not of MTHFR 677 C>T, MTR 2756 A>G, MTRR 66 A>G and TCN2 776 C>G) with ischaemic cerebrovascular disease in Sicily.
Cerebrovascular Disorders
Association of MTHFR C677T polymorphism and risk of cerebrovascular disease in Chinese population: an updated meta-analysis.
Cerebrovascular Disorders
C677T (RS1801133 ) MTHFR gene polymorphism frequency in a colombian population.
Cerebrovascular Disorders
Coexistence of Neurofibromatosis Type-1 and MTHFR C677T Gene Mutation in a Young Stroke Patient: A Case Report.
Cerebrovascular Disorders
Frequency of APOE, MTHFR and ACE polymorphisms in the Zambian population.
Cerebrovascular Disorders
Genetic polymorphisms and cerebrovascular disease in children with sickle cell anemia from Rio de Janeiro, Brazil.
Cerebrovascular Disorders
Homozygous C677T mutation in the MTHFR gene as an independent risk factor for multiple small-artery occlusions.
Cerebrovascular Disorders
Investigation of MTHFR gene C677T polymorphism in cardiac syndrome X patients.
Cerebrovascular Disorders
Methylenetetrahydrofolate reductase gene polymorphism is not related to the risk of ischemic cerebrovascular disease in a Brazilian population.
Cerebrovascular Disorders
Methylenetetrahydrofolate reductase gene polymorphism: relation to blood pressure and cerebrovascular disease.
Cerebrovascular Disorders
Methylenetetrahydrofolate reductase homozygous mutation in a young boy with cerebellar infarction.
Cerebrovascular Disorders
MTHFR Gene Mutations Correlate with White Matter Disease Burden and Predict Cerebrovascular Disease and Dementia.
Cerebrovascular Disorders
Mutation in the methylenetetrahydrofolate reductase gene might be a risk factor for cerebrovascular disease in peripartum and under oral contraceptive use.
Cerebrovascular Disorders
No association between MTHFR gene polymorphism and diabetic nephropathy in Japanese type II diabetic patients with proliferative diabetic retinopathy.
Cerebrovascular Disorders
Pathogenicity of thermolabile methylenetetrahydrofolate reductase for vascular dementia.
Cerebrovascular Disorders
Polymorphism of apoprotein E (APOE), methylenetetrahydrofolate reductase (MTHFR) and paraoxonase (PON1) genes in patients with cerebrovascular disease.
Cerebrovascular Disorders
Prevalence of methylenetetrahydrofolate reductase C677T and its association with arterial and venous thrombosis in the Chinese population.
Cerebrovascular Disorders
Role of a common mutation in the homocysteine regulatory enzyme methylenetetrahydrofolate reductase in ischemic stroke.
Cerebrovascular Disorders
Role of Methylenetetrahydrofolate Reductase Gene (MTHFR) 677C>T Polymorphism in Pediatric Cerebrovascular Disorders.
Cerebrovascular Disorders
The effect of MTHFR c.677C>T on plasma homocysteine levels depends on health, age and smoking.
Cerebrovascular Disorders
The relation between erythrocyte volume and folate levels is influenced by a common mutation in the methylenetetrahydrofolate reductase (MTHFR) gene (C677T).
Cerebrovascular Disorders
[Correlation analysis between plasma homocysteine level and polymorphism of homocysteine metabolism related enzymes in ischemic cerebrovascular or cardiovascular diseases]
Cerebrovascular Disorders
[Prevalence of methylenetetrahydrofolate reductase C677T mutation among patients with acute ischemic cerebrovascular disease in Aragon]
Cerebrovascular Disorders
[Study on homocysteine metabolism related enzymes gene mutations in Chinese patients with ischemic cardiovascular and cerebrovascular diseases]
Cervical Intraepithelial Neoplasia
A lower degree of PBMC L1 methylation in women with lower folate status may explain the MTHFR C677T polymorphism associated higher risk of CIN in the US post folic acid fortification era.
Cervical Intraepithelial Neoplasia
Association between MTHFR C677T, MTHFR A1298C and MS A2756G polymorphisms and risk of cervical intraepithelial neoplasia II/III and cervical cancer: A meta-analysis.
Cervical Intraepithelial Neoplasia
Common polymorphisms in methylenetetrahydrofolate reductase gene are associated with risks of cervical intraepithelial neoplasia and cervical cancer in women with low serum folate and vitamin B12.
Cervical Intraepithelial Neoplasia
Lack of association between methylenetetrahydrofolate reductase C677T polymorphism, HPV infection and cervical intraepithelial neoplasia in Brazilian women.
Cervical Intraepithelial Neoplasia
Methylenetetrahydrofolate reductase (MTHFR) and susceptibility for (pre)neoplastic cervical disease.
Cervical Intraepithelial Neoplasia
Methylenetetrahydrofolate reductase (MTHFR) polymorphism increases the risk of cervical intraepithelial neoplasia.
Cervical Intraepithelial Neoplasia
Methylenetetrahydrofolate reductase C677T polymorphism and susceptibility to cervical cancer and cervical intraepithelial neoplasia: a meta-analysis.
Cervical Intraepithelial Neoplasia
Methylenetetrahydrofolate reductase polymorphism C677T is not associated to the risk of cervical dysplasia.
Cervical Intraepithelial Neoplasia
MTHFR/p53 polymorphisms as genetic factors for cervical intraepithelial neoplasia and cervical cancer in HPV-infected Mexican women.
Cervical Intraepithelial Neoplasia
Polymorphisms in Genes Involved in Folate Metabolism Modify the Association of Dietary and Circulating Folate and Vitamin B-6 with Cervical Neoplasia.
Cervical Intraepithelial Neoplasia
Protective association of MTHFR polymorphism on cervical intraepithelial neoplasia is modified by riboflavin status.
Cervical Intraepithelial Neoplasia
The effect of methylenetetrahydrofolate reductase polymorphism C677T on cervical cancer in Korean women.
Cervical Intraepithelial Neoplasia
The effects of polymorphisms in methylenetetrahydrofolate reductase (MTHFR), methionine synthase (MTR), and methionine synthase reductase (MTRR) on the risk of cervical intraepithelial neoplasia and cervical cancer in Korean women.
Cervical Intraepithelial Neoplasia
The Impact of MTHFR 1298 A?>?C and 677 C?>?T Gene Polymorphisms as Susceptibility Risk Factors in Cervical Intraepithelial Neoplasia Related to HPV and Sexually Transmitted Infections.
Cervical Intraepithelial Neoplasia
Women with polymorphisms of methylenetetrahydrofolate reductase (MTHFR) and methionine synthase (MS) are less likely to have cervical intraepithelial neoplasia (CIN) 2 or 3.
Cholangiocarcinoma
MTHFR Polymorphisms and Opisthorchis viverrini Infection: a Relationship with Increased Susceptibility to Cholangiocarcinoma in Thailand.
Cholangiocarcinoma
Polymorphisms of 5,10-methylenetetrahydrofolate reductase (MTHFR C677T) and thymidylate synthase enhancer region (TSER) as a risk factor of cholangiocarcinoma in a Korean population.
Cholangiocarcinoma
Risk factors for cholangiocarcinoma in high-risk area of Thailand: Role of lifestyle, diet and methylenetetrahydrofolate reductase polymorphisms.
Cholelithiasis
Relationship of Cholelithiasis and Urolithiasis with Methylenetetrahydrofolate Reductase Polymorphisms.
Choline Deficiency
Disturbed One-Carbon Metabolism Causing Adverse Reproductive Outcomes in Mice Is Associated with Altered Expression of Apolipoprotein AI and Inflammatory Mediators PPAR?, Interferon-?, and Interleukin-10.
Chondrosarcoma
Methylenetetrahydrofolate reductase C677T gene polymorphism in osteosarcoma and chondrosarcoma patients.
Choroidal Neovascularization
Combined choroidal neovascularization and hypopituitarism in a patient with homozygous mutation in methylenetetrahydrofolate reductase gene.
Citrullinemia
Epidemiology of rare diseases detected by newborn screening in the Czech Republic.
Cleft Lip
Analysis of MTHFR Gene C.677C>T and C.1298A>C Polymorphisms in Iranian Patients with Non-Syndromic Cleft Lip and Palate.
Cleft Lip
Association between Maternal MTHFR Polymorphisms and Nonsyndromic Cleft Lip with or without Cleft Palate in Offspring, A Meta-Analysis Based on 15 Case-Control Studies.
Cleft Lip
Association between methylenetetrahydrofolate reductase polymorphisms and non-syndromic cleft lip with or without palate susceptibility: an updated systematic review and meta-analysis.
Cleft Lip
Association between MTHFR C677T and A1298C Polymorphisms and NSCL/P Risk in Asians: A Meta-Analysis.
Cleft Lip
Association Between Nonsyndromic Cleft Lip and Palate and 2 Polymorphic Loci: A Meta-Analysis.
Cleft Lip
Association of Fetal MTHFR 677C?>?T Polymorphism with Non-Syndromic Cleft Lip with or without Palate Risk: A Systematic Review and Meta-Analysis.
Cleft Lip
Association of MTHFR 1298A?>?C Polymorphism with Susceptibility to Non-Syndromic Cleft Lip with or without Palate: A Case-Control Study and Meta-Analysis.
Cleft Lip
Association of Transforming Growth Factor Alpha and Methylenetetrahydrofolate reductase gene variants with nonsyndromic cleft lip and palate in the Indian population.
Cleft Lip
Common Mutations of the Methylenetetrahydrofolate Reductase (MTHFR) Gene in Non-Syndromic Cleft Lips and Palates Children in North-West of Iran.
Cleft Lip
Determination of Methylenetetrahydrofolate Reductase (MTHFR) gene polymorphism in Turkish patients with nonsyndromic cleft lip and palate.
Cleft Lip
Does the interaction between maternal folate intake and the methylenetetrahydrofolate reductase polymorphisms affect the risk of cleft lip with or without cleft palate?
Cleft Lip
Family-based association study of the MTHFR polymorphism C677T in patients with nonsyndromic cleft lip and palate from central Europe.
Cleft Lip
Fetal and maternal MTHFR C677T genotype, maternal folate intake and the risk of nonsyndromic oral clefts.
Cleft Lip
Incidence Assessment of MTHFR C677T and A1298C Polymorphisms in Iranian Non-syndromic Cleft Lip and/or Palate Patients.
Cleft Lip
Infant C677T mutation in MTHFR, maternal periconceptional vitamin use, and cleft lip.
Cleft Lip
Infant C677T mutation in MTHFR, maternal periconceptional vitamin use, and risk of nonsyndromic cleft lip.
Cleft Lip
Influence of the MTHFR genotype on the rate of malformations following exposure to antiepileptic drugs in utero.
Cleft Lip
LINE-1 methylation in cleft lip tissues: Influence of infant MTHFR c.677C>T genotype.
Cleft Lip
Maternal C677T MTHFR polymorphism and environmental factors are associated with cleft lip and palate in a Mexican population.
Cleft Lip
Maternal MTHFR genotype contributes to the risk of non-syndromic cleft lip and palate.
Cleft Lip
Maternal MTHFR interacts with the offspring's BCL3 genotypes, but not with TGFA, in increasing risk to nonsyndromic cleft lip with or without cleft palate.
Cleft Lip
Maternal MTHFR variant forms increase the risk in offspring of isolated nonsyndromic cleft lip with or without cleft palate.
Cleft Lip
Methylenetetrahydrofolate Reductase C677T and A1298C Polymorphisms and Nonsyndromic Orofacial Clefts Susceptibility in a Southern Chinese Population.
Cleft Lip
MTHFR 677TT Alone and IRF6 820GG Together with MTHFR 677CT, But Not MTHFR A1298C, Are Risks for Nonsyndromic Cleft Lip with or without Cleft Palate in an Indian Population.
Cleft Lip
MTHFR c.677C>T is a risk factor for non-syndromic cleft lip with or without cleft palate in Chile.
Cleft Lip
MTHFR C677T and A1298C polymorphisms and risk of nonsyndromic orofacial clefts in a south Indian population.
Cleft Lip
MTHFR C677T polymorphism and risk of nonsyndromic cleft lip with or without cleft palate in the Moroccan population.
Cleft Lip
MTHFR is not a risk factor in the development of isolated nonsyndromic cleft lip and palate.
Cleft Lip
MTHFR rs2274976 polymorphism is a risk marker for nonsyndromic cleft lip with or without cleft palate in the Brazilian population.
Cleft Lip
MTHFR, TGFB3, and TGFA polymorphisms and their association with the risk of non-syndromic cleft lip and cleft palate in China.
Cleft Lip
MTR, MTRR, and MTHFR Gene Polymorphisms and Susceptibility to Nonsyndromic Cleft Lip With or Without Cleft Palate.
Cleft Lip
Non-syndromic cleft palate: Association analysis on three gene polymorphisms of the folate pathway in Asian and Italian populations.
Cleft Lip
Role of the C677T polymorphism at the MTHFR gene on risk to nonsyndromic cleft lip with/without cleft palate: results from a case-control study in Brazil.
Cleft Lip
rs1801133C>T polymorphism in MTHFR is a risk factor for nonsyndromic cleft lip with or without cleft palate in the Brazilian population.
Cleft Lip
Single-nucleotide polymorphisms of methylenetetrahydrofolate reductase gene in a South Indian cohort with nonsyndromic cleft lip with or without palate.
Cleft Lip
Strong Association of C677T Polymorphism of Methylenetetrahydrofolate Reductase Gene With Nosyndromic Cleft Lip/Palate (nsCL/P).
Cleft Lip
Variable contribution of the MTHFR C677T polymorphism to non-syndromic cleft lip and palate risk in China.
Cleft Lip
[Allelic polymorphism of MTHFR, MTR and MTRR genes in patients with cleft lip and/or palate and their mothers].
Cleft Lip
[Association between parental MTHFR gene polymorphism 677C/T and nonsyndromic cleft lip and palate in offspring].
Cleft Lip
[Association of methylenetetrahydrofolate reductase A1298C polymorphisms with non-syndromic cleft lip with or without cleft palate].
Cleft Lip
[Log-linear model used in the hybrid design of case-parents triad/control-mother dyad].
Cleft Lip
[MTHFR gene silencing affects mouse embryonic palatal mesenchymal cell proliferation and apoptosis]
Cleft Lip
[Relationship between genetic polymorphism of MTHFR C677T and nonsyndromic cleft lip with or without cleft palate in Shanxi Province of China].
Cleft Lip
[Relationship between genetic polymorphisms of MTHFR C677T and nonsymdromic cleft lip with or without palate.]
Cleft Lip
[Relationship between nonsyndromic cleft lip with or without cleft palate (NSCL/P) and genetic polymorphisms of MTHFR C677T and A1298C]
Cleft Palate
5,10-Methylenetetrahydrofolate reductase (MTHFR) C677T/A1298C polymorphisms in patients with nonsyndromic cleft lip and palate.
Cleft Palate
Association between Maternal MTHFR Polymorphisms and Nonsyndromic Cleft Lip with or without Cleft Palate in Offspring, A Meta-Analysis Based on 15 Case-Control Studies.
Cleft Palate
Association between methylenetetrahydrofolate reductase polymorphisms and non-syndromic cleft lip with or without palate susceptibility: an updated systematic review and meta-analysis.
Cleft Palate
Association of Fetal MTHFR 677C?>?T Polymorphism with Non-Syndromic Cleft Lip with or without Palate Risk: A Systematic Review and Meta-Analysis.
Cleft Palate
Fetal and maternal MTHFR C677T genotype, maternal folate intake and the risk of nonsyndromic oral clefts.
Cleft Palate
Incidence Assessment of MTHFR C677T and A1298C Polymorphisms in Iranian Non-syndromic Cleft Lip and/or Palate Patients.
Cleft Palate
Infant C677T mutation in MTHFR, maternal periconceptional vitamin use, and cleft lip.
Cleft Palate
Maternal MTHFR interacts with the offspring's BCL3 genotypes, but not with TGFA, in increasing risk to nonsyndromic cleft lip with or without cleft palate.
Cleft Palate
Maternal MTHFR variant forms increase the risk in offspring of isolated nonsyndromic cleft lip with or without cleft palate.
Cleft Palate
Maternal vitamin use, infant C677T mutation in MTHFR, and isolated cleft palate risk.
Cleft Palate
Methylenetetrahydrofolate Reductase C677T and A1298C Polymorphisms and Nonsyndromic Orofacial Clefts Susceptibility in a Southern Chinese Population.
Cleft Palate
MTHFR 677TT Alone and IRF6 820GG Together with MTHFR 677CT, But Not MTHFR A1298C, Are Risks for Nonsyndromic Cleft Lip with or without Cleft Palate in an Indian Population.
Cleft Palate
MTHFR c.677C>T is a risk factor for non-syndromic cleft lip with or without cleft palate in Chile.
Cleft Palate
MTHFR C677T and A1298C polymorphisms and risk of nonsyndromic orofacial clefts in a south Indian population.
Cleft Palate
MTHFR C677T polymorphism and risk of nonsyndromic cleft lip with or without cleft palate in the Moroccan population.
Cleft Palate
MTHFR rs2274976 polymorphism is a risk marker for nonsyndromic cleft lip with or without cleft palate in the Brazilian population.
Cleft Palate
MTHFR, TGFB3, and TGFA polymorphisms and their association with the risk of non-syndromic cleft lip and cleft palate in China.
Cleft Palate
MTR, MTRR, and MTHFR Gene Polymorphisms and Susceptibility to Nonsyndromic Cleft Lip With or Without Cleft Palate.
Cleft Palate
Non-syndromic cleft palate: Association analysis on three gene polymorphisms of the folate pathway in Asian and Italian populations.
Cleft Palate
Role of the C677T polymorphism at the MTHFR gene on risk to nonsyndromic cleft lip with/without cleft palate: results from a case-control study in Brazil.
Cleft Palate
rs1801133C>T polymorphism in MTHFR is a risk factor for nonsyndromic cleft lip with or without cleft palate in the Brazilian population.
Cleft Palate
Salivary microRNAs as new molecular markers in cleft lip and palate: a new frontier in molecular medicine.
Cleft Palate
Study of ABCB1 multidrug resistance protein in a common orofacial malformation.
Cleft Palate
[Association between parental MTHFR gene polymorphism 677C/T and nonsyndromic cleft lip and palate in offspring].
Cleft Palate
[Association of methylenetetrahydrofolate reductase A1298C polymorphisms with non-syndromic cleft lip with or without cleft palate].
Cleft Palate
[Relationship between genetic polymorphism of MTHFR C677T and nonsyndromic cleft lip with or without cleft palate in Shanxi Province of China].
Cleft Palate
[Relationship between nonsyndromic cleft lip with or without cleft palate (NSCL/P) and genetic polymorphisms of MTHFR C677T and A1298C]
Clubfoot
The C677T polymorphism in the methylenetetrahydrofolate reductase gene (MTHFR), maternal use of folic acid supplements, and risk of isolated clubfoot: A case-parent-triad analysis.
Clubfoot
Whole genome sequencing identifies ANXA3 and MTHFR mutations in a large family with an unknown equinus deformity associated genetic disorder.
coagulation factor xiia deficiency
Retinal vein occlusion in child with rare mutations in genes for thrombophilia.
Colitis
Methionine synthase A2756G polymorphism may predict ulcerative colitis and methylenetetrahydrofolate reductase C677T pancolitis, in Central China.
Colitis, Ulcerative
Combined portal, splenic and mesenteric venous thrombosis in inactive ulcerative colitis with heterozygous mutation in MTHFR gene: A rare case of thrombophilia.
Colitis, Ulcerative
Genetic polymorphism of methylenetetrahydrofolate reductase G1793A, hyperhomocysteinemia, and folate deficiency correlate with ulcerative colitis in central China.
Colitis, Ulcerative
Genotypes 677TT and 677CT+1298AC of methylenetetrahydrofolate reductase are associated with the severity of ulcerative colitis in central China.
Colitis, Ulcerative
High prevalence of combined thrombophilic abnormalities in patients with inflammatory bowel disease.
Colitis, Ulcerative
Methionine synthase A2756G polymorphism may predict ulcerative colitis and methylenetetrahydrofolate reductase C677T pancolitis, in Central China.
Colitis, Ulcerative
Methylenetetrahydrofolate reductase C677T variant in Moroccan patients with inflammatory bowel disease.
Colitis, Ulcerative
Polymorphisms of glutathione S-transferase and methylenetetrahydrofolate reductase genes in Moldavian patients with ulcerative colitis: Genotype-phenotype correlation.
Colitis, Ulcerative
The association of the MTHFR C677T polymorphism with inflammatory bowel diseases in the Israeli Jewish population: An example of genetic heterogeneity.
Colitis, Ulcerative
The methylenetetrahydrofolate reductase 1298 A>C polymorphism is associated with an increased risk of inflammatory bowel disease: evidence from a meta-analysis.
Colitis, Ulcerative
[The associations of methylenetetrahydrofolate reductase gene C677T and A1298C polymorphisms and ulcerative colitis].
Colitis, Ulcerative
[The relationship of methylenetetrahydrofolate reductase G1793A gene polymorphism, hyperhomocysteinaemia and ulcerative colitis].
Colonic Neoplasms
5,10-methylenetetrahydrofolate reductase 677 and 1298 polymorphisms, folate intake, and microsatellite instability in colon cancer.
Colonic Neoplasms
5,10-Methylenetetrahydrofolate reductase codon 677 and 1298 polymorphisms and colon cancer in African Americans and whites.
Colonic Neoplasms
5,10-Methylenetetrahydrofolate reductase polymorphisms and colon cancer risk: a meta-analysis.
Colonic Neoplasms
Association between MTHFR polymorphism (C677T) with nonfamilial colorectal cancer.
Colonic Neoplasms
Association between the MTHFR C677T polymorphism and risk of cancer: evidence from 446 case-control studies.
Colonic Neoplasms
Association of methylenetetrahydrofolate reductase gene polymorphisms and sex-specific survival in patients with metastatic colon cancer.
Colonic Neoplasms
Association of MTHFR, MTR, MTRR, RFC1, and DHFR Gene Polymorphisms with Susceptibility to Sporadic Colon Cancer.
Colonic Neoplasms
Association of the methylenetetrahydrofolate reductase polymorphism in Korean patients with childhood acute lymphoblastic leukemia.
Colonic Neoplasms
Associations between 5,10-methylenetetrahydrofolate reductase codon 677 and 1298 genetic polymorphisms and environmental factors with reference to susceptibility to colorectal cancer: a case-control study in an Indian population.
Colonic Neoplasms
Diets, polymorphisms of methylenetetrahydrofolate reductase, and the susceptibility of colon cancer and rectal cancer.
Colonic Neoplasms
Genetic polymorphisms in one-carbon metabolism: associations with CpG island methylator phenotype (CIMP) in colon cancer and the modifying effects of diet.
Colonic Neoplasms
Genetic polymorphisms of methylenetetrahydrofolate reductase and susceptibility to colorectal cancer.
Colonic Neoplasms
Genetic variability in the MTHFR gene and colorectal cancer risk using the colorectal cancer family registry.
Colonic Neoplasms
Intraindividual somatic variations in MTHFR gene polymorphisms in relation to colon cancer.
Colonic Neoplasms
Methylenetetrahydrofolate reductase 677 C-->T polymorphism and risk of proximal colon cancer in north Italy.
Colonic Neoplasms
Methylenetetrahydrofolate reductase polymorphism (677 c>t) predicts long time to progression in metastatic colon cancer treated with 5-Fluorouracil and folinic Acid.
Colonic Neoplasms
Methylenetetrahydrofolate reductase polymorphism, alcohol intake, and risks of colon and rectal cancers in Korea.
Colonic Neoplasms
Methylenetetrahydrofolate reductase polymorphism, dietary interactions, and risk of colorectal cancer.
Colonic Neoplasms
MTHFR (C677T) polymorphisms and stage III colon cancer: response to therapy.
Colonic Neoplasms
MTHFR C677T and A1298C polymorphisms: diet, estrogen, and risk of colon cancer.
Colonic Neoplasms
MTHFR variants reduce the risk of G:C->A:T transition mutations within the p53 tumor suppressor gene in colon tumors.
Colonic Neoplasms
Pharmacogenetic Predictors of Outcome in Patients with Stage II and III Colon Cancer Treated with Oxaliplatin and Fluoropyrimidine-Based Adjuvant Chemotherapy.
Colonic Neoplasms
Polymorphisms in the reduced folate carrier, thymidylate synthase, or methionine synthase and risk of colon cancer.
Colonic Neoplasms
Polymorphisms of MTHFR C677T and A1298C associated with survival in patients with colorectal cancer treated with 5-fluorouracil-based chemotherapy.
Colonic Neoplasms
Recurrent thrombophlebitis in a colon cancer patient with C677T heterozygous genotype for MTHFR treated with 5-fluorouracil-based adjuvant chemotherapy.
Colonic Neoplasms
Risk factors for colon cancer in Northeastern Thailand: interaction of MTHFR codon 677 and 1298 genotypes with environmental factors.
Colonic Neoplasms
SHMT1 1420 and MTHFR 677 variants are associated with rectal but not colon cancer.
Colonic Neoplasms
The association between methylenetetrahydrofolate reductase polymorphism and promoter methylation in proximal colon cancer.
Colonic Neoplasms
The frequent 5,10-methylenetetrahydrofolate reductase C677T polymorphism is associated with a common haplotype in whites, Japanese, and Africans.
Colonic Neoplasms
The methylenetetrahydrofolate reductase (MTHFR) gene in colorectal cancer: role in tumor development and significance of allelic loss in tumor progression.
Colonic Neoplasms
The methylenetetrahydrofolate reductase C677T mutation induces cell-specific changes in genomic DNA methylation and uracil misincorporation: a possible molecular basis for the site-specific cancer risk modification.
Colonic Neoplasms
The MTHFR C677T and DeltaDNMT3B C-149T polymorphisms confer different risks for right- and left-sided colorectal cancer.
Colonic Neoplasms
Thymidylate synthase haplotype is associated with tumor recurrence in stage II and stage III colon cancer.
Colorectal Neoplasms
5-Fluorouracil degradation rate could predict toxicity in stages II-III colorectal cancer patients undergoing adjuvant FOLFOX.
Colorectal Neoplasms
A methylenetetrahydrofolate reductase polymorphism and the risk of colorectal cancer.
Colorectal Neoplasms
A pharmacogenetic study to investigate the role of dietary carcinogens in the etiology of colorectal cancer.
Colorectal Neoplasms
A polymorphism in the methylenetetrahydrofolate reductase gene predisposes to colorectal cancers with microsatellite instability.
Colorectal Neoplasms
A polymorphism of the methionine synthase gene: association with plasma folate, vitamin B12, homocyst(e)ine, and colorectal cancer risk.
Colorectal Neoplasms
A prospective study of methylenetetrahydrofolate reductase and methionine synthase gene polymorphisms, and risk of colorectal adenoma.
Colorectal Neoplasms
Allele and Genotype Frequencies of the Polymorphic Methylenetetrahydrofolate Reductase and Colorectal Cancer among Jordanian Population.
Colorectal Neoplasms
Association between MTHFR polymorphism (C677T) with nonfamilial colorectal cancer.
Colorectal Neoplasms
Association between MTHFR polymorphisms and overall survival of colorectal cancer patients in Northeast China.
Colorectal Neoplasms
Association between the 1793G> A MTHFR polymorphism and sporadic colorectal cancer in Iran.
Colorectal Neoplasms
Association between the MTHFR A1298C polymorphism and risk of cancer: evidence from 265 case-control studies.
Colorectal Neoplasms
Association between the MTHFR C677T polymorphism and risk of cancer: evidence from 446 case-control studies.
Colorectal Neoplasms
Association of C677T and A1298C MTHFR Polymorphisms and Fluoropyrimidine-induced Toxicity in Mestizo Patients With Metastatic Colorectal Cancer.
Colorectal Neoplasms
Association of Folate and Vitamins Involved in the 1-Carbon Cycle with Polymorphisms in the Methylenetetrahydrofolate Reductase Gene (MTHFR) and Global DNA Methylation in Patients with Colorectal Cancer.
Colorectal Neoplasms
Association of methylenetetrahydrofolate reductase C677T and A1298C polymorphisms with colorectal cancer risk: A meta-analysis.
Colorectal Neoplasms
Association of methylenetetrahydrofolate reductase gene polymorphisms & colorectal cancer in India.
Colorectal Neoplasms
Association of MTHFR C677T polymorphisms and colorectal cancer risk in Asians: evidence of 12,255 subjects.
Colorectal Neoplasms
Association of polymorphisms MTHFR C677T and A1298C with risk of colorectal cancer, genetic and epigenetic characteristic of tumors, and response to chemotherapy.
Colorectal Neoplasms
Association of single nucleotide polymorphisms in MTHFR and ABCG2 with the different efficacy of first-line chemotherapy in metastatic colorectal cancer.
Colorectal Neoplasms
Association of the 677C -->T polymorphism in the MTHFR gene with colorectal cancer in Mexican patients.
Colorectal Neoplasms
Associations between 5,10-methylenetetrahydrofolate reductase codon 677 and 1298 genetic polymorphisms and environmental factors with reference to susceptibility to colorectal cancer: a case-control study in an Indian population.
Colorectal Neoplasms
Associations between two common variants C677T and A1298C in the methylenetetrahydrofolate reductase gene and measures of folate metabolism and DNA stability (strand breaks, misincorporated uracil, and DNA methylation status) in human lymphocytes in vivo.
Colorectal Neoplasms
C677T and A1298C MTHFR gene polymorphisms and response to fluoropyrimidine-based chemotherapy in Mestizo patients with metastatic colorectal cancer.
Colorectal Neoplasms
C677T and A1298C mutations in the MTHFR gene and survival in colorectal cancer.
Colorectal Neoplasms
C677T single nucleotide polymorphism of methylenetetrahydrofolate reductase gene and colorectal cancer.
Colorectal Neoplasms
Chapter 13 methylenetetrahydrofolate reductase, common polymorphisms, and relation to disease.
Colorectal Neoplasms
Clinical utility of ABCB1 genotyping for preventing toxicity in treatment with irinotecan.
Colorectal Neoplasms
Colon cancer and genetic variation in folate metabolism: the clinical bottom line.
Colorectal Neoplasms
Colorectal cancer and the methylenetetrahydrofolate reductase 677C -> T and methionine synthase 2756A -> G polymorphisms: a study of 2,168 case-control pairs from the JANUS cohort.
Colorectal Neoplasms
Deciphering the potential value of 5-fluorouracil metabolic enzymes in predicting prognosis and treatment response of colorectal cancer patients.
Colorectal Neoplasms
Dietary B vitamin and methionine intake and MTHFR C677T genotype on risk of colorectal tumors in Lynch syndrome: the GEOLynch cohort study.
Colorectal Neoplasms
Dietary intake of folate and alcohol, MTHFR C677T polymorphism, and colorectal cancer risk in Korea.
Colorectal Neoplasms
Different roles of MTHFR C677T and A1298C polymorphisms in colorectal adenoma and colorectal cancer: a meta-analysis.
Colorectal Neoplasms
DPYD*2A and MTHFR C677T predict toxicity and efficacy, respectively, in patients on chemotherapy with 5-fluorouracil for colorectal cancer.
Colorectal Neoplasms
DPYD, TYMS and MTHFR Genes Polymorphism Frequencies in a Series of Turkish Colorectal Cancer Patients.
Colorectal Neoplasms
Early disease relapse in a patient with colorectal cancer who harbors genetic variants of DPYD, TYMS, MTHFR and DHFR after treatment with 5-fluorouracil-based chemotherapy.
Colorectal Neoplasms
Effect of DPYD, MTHFR, ABCB1, XRCC1, ERCC1 and GSTP1 on chemotherapy related toxicity in colorectal carcinoma.
Colorectal Neoplasms
Effects of MTHFR Genetic Polymorphisms on Toxicity and Clinical Response of Irinotecan-Based Chemotherapy in Patients with Colorectal Cancer.
Colorectal Neoplasms
Evaluation of association studies and meta-analyses of MTHFR gene polymorphisms in colorectal cancer.
Colorectal Neoplasms
Evaluation of the MTHFR C677T Polymorphism as a Risk Factor for Colorectal Cancer in Asian Populations.
Colorectal Neoplasms
Expression and clinical significance of methylenetetrahydrofolate reductase in patients with colorectal cancer.
Colorectal Neoplasms
Folate Intake, MTHFR Polymorphisms, and the Risk of Colorectal Cancer: A Systematic Review and Meta-Analysis.
Colorectal Neoplasms
Folate Levels and Polymorphisms in the Genes MTHFR, MTR, and TS in Colorectal Cancer.
Colorectal Neoplasms
Folate-genetics and colorectal neoplasia: What we know and need to know next.
Colorectal Neoplasms
Folic acid and colorectal cancer prevention: molecular mechanisms and epidemiological evidence (Review).
Colorectal Neoplasms
Gene Polymorphisms MTHFRC677T and MTRA2756G as Predictive Factors in Adjuvant Chemotherapy for Stage III Colorectal Cancer.
Colorectal Neoplasms
Genetic markers for toxicity of adjuvant oxaliplatin and fluoropyrimidines in the phase III TOSCA trial in high-risk colon cancer patients.
Colorectal Neoplasms
Genetic polymorphism of enzymes involved in xenobiotic metabolism and the risk of colorectal cancer.
Colorectal Neoplasms
Genetic polymorphisms of methylenetetrahydrofolate reductase and colorectal cancer and adenoma.
Colorectal Neoplasms
Genetic polymorphisms of methylenetetrahydrofolate reductase and susceptibility to colorectal cancer.
Colorectal Neoplasms
Genetic variability in the MTHFR gene and colorectal cancer risk using the colorectal cancer family registry.
Colorectal Neoplasms
Genetic variants in 3'-UTRs of methylenetetrahydrofolate reductase (MTHFR) predict colorectal cancer susceptibility in Koreans.
Colorectal Neoplasms
Genetic Variants of Methyl Metabolizing Enzymes and Epigenetic Regulators: Associations with Promoter CpG Island Hypermethylation in Colorectal Cancer.
Colorectal Neoplasms
Germline polymorphisms in the one-carbon metabolism pathway and DNA methylation in colorectal cancer.
Colorectal Neoplasms
Impact of MTHFR gene C677T polymorphism on Bcl-2 gene methylation and protein expression in colorectal cancer.
Colorectal Neoplasms
Impact of SHMT1 polymorphism on the clinical outcome of patients with metastatic colorectal cancer treated with first-line FOLFIRI+bevacizumab.
Colorectal Neoplasms
Impact of the MTHFR C677T polymorphism on colorectal cancer in a population with low genetic variability.
Colorectal Neoplasms
Influence of methylenetetrahydrofolate reductase gene polymorphisms C677T and A1298C on age-associated risk for colorectal cancer in a caucasian lynch syndrome population.
Colorectal Neoplasms
Investigating the methylation status of DACT2 gene and its association with MTHFR C677T polymorphism in patients with colorectal cancer.
Colorectal Neoplasms
Involvement of genetic factors and lifestyle on the occurrence of colorectal and gastric cancer.
Colorectal Neoplasms
Letter to the editor: a meta-analyses of association between polymorphism of MTHFR A1298C and colorectal cancer risk.
Colorectal Neoplasms
Letter to the editor: a meta-analysis of MTHFR C677T polymorphism and colorectal cancer risk in East Asians.
Colorectal Neoplasms
Linkage disequilibrium between the 677C>T and 1298A>C polymorphisms in human methylenetetrahydrofolate reductase gene and their contributions to risk of colorectal cancer.
Colorectal Neoplasms
Localized depletion: the key to colorectal cancer risk mediated by MTHFR genotype and folate?
Colorectal Neoplasms
Loss of heterozygosity of methylenetetrahydrofolate reductase in colon carcinomas.
Colorectal Neoplasms
Low folate status, and MTHFR 677C?>?T and MTR 2756A?>?G polymorphisms associated with colorectal cancer risk in Thais: a case-control study.
Colorectal Neoplasms
Meta- and Pooled Analyses of the Methylenetetrahydrofolate Reductase (MTHFR) C677T Polymorphism and Colorectal Cancer: A HuGE-GSEC Review.
Colorectal Neoplasms
Meta-Prediction of MTHFR Gene Polymorphism Mutations and Associated Risk for Colorectal Cancer.
Colorectal Neoplasms
Methionine Synthase Reductase Gene A66G Polymorphism is Associated with Risk of Colorectal Cancer.
Colorectal Neoplasms
Methylene tetrahydrofolate reductase genotype modifies the chemopreventive effect of folate in colorectal adenoma, but not colorectal cancer.
Colorectal Neoplasms
Methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms and FOLFOX response in colorectal cancer patients.
Colorectal Neoplasms
Methylenetetrahydrofolate reductase (MTHFR) variants and bladder cancer: a population-based case-control study.
Colorectal Neoplasms
Methylenetetrahydrofolate reductase (MTHFR) variants and fluorouracil-based treatments in colorectal cancer.
Colorectal Neoplasms
Methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and colorectal cancer: the Fukuoka Colorectal Cancer Study.
Colorectal Neoplasms
Methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and fluorouracil-based treatment in Taiwan colorectal cancer.
Colorectal Neoplasms
Methylenetetrahydrofolate reductase C677T gene polymorphism and colorectal cancer risk: A case-control study.
Colorectal Neoplasms
Methylenetetrahydrofolate reductase C677T genotype affects promoter methylation of tumor-specific genes in sporadic colorectal cancer through an interaction with folate/vitamin B12 status.
Colorectal Neoplasms
Methylenetetrahydrofolate reductase C677T is not associated with expression of pyrimidine metabolic enzyme genes in colorectal cancer.
Colorectal Neoplasms
Methylenetetrahydrofolate reductase C677T polymorphism and colorectal cancer susceptibility: a meta-analysis.
Colorectal Neoplasms
Methylenetetrahydrofolate reductase C677T polymorphism does not alter folic acid deficiency-induced uracil incorporation into primary human lymphocyte DNA in vitro.
Colorectal Neoplasms
Methylenetetrahydrofolate reductase C677T polymorphism in patients with gastric and colorectal cancer in a Korean population.
Colorectal Neoplasms
Methylenetetrahydrofolate reductase C677T polymorphism in patients with gastric and colorectal cancer.
Colorectal Neoplasms
Methylenetetrahydrofolate reductase deficiency and low dietary folate reduce tumorigenesis in Apc min/+ mice.
Colorectal Neoplasms
Methylenetetrahydrofolate reductase gene germ-line C677T and A1298C SNPs are associated with colorectal cancer risk in the Turkish population.
Colorectal Neoplasms
Methylenetetrahydrofolate reductase gene polymorphisms and lung cancer: a meta-analysis.
Colorectal Neoplasms
Methylenetetrahydrofolate reductase gene polymorphisms and response to fluorouracil-based treatment in advanced colorectal cancer patients.
Colorectal Neoplasms
Methylenetetrahydrofolate reductase gene polymorphisms and the risk of colorectal carcinoma in a sample of Egyptian individuals.
Colorectal Neoplasms
Methylenetetrahydrofolate reductase gene polymorphisms: genomic predictors of clinical response to fluoropyrimidine-based chemotherapy?
Colorectal Neoplasms
Methylenetetrahydrofolate reductase genotypes and haplotypes associated with susceptibility to colorectal cancer in an eastern Chinese Han population.
Colorectal Neoplasms
Methylenetetrahydrofolate reductase polymorphism and risk of colorectal adenomas.
Colorectal Neoplasms
Methylenetetrahydrofolate reductase polymorphism in advanced colorectal cancer: a novel genomic predictor of clinical response to fluoropyrimidine-based chemotherapy.
Colorectal Neoplasms
Methylenetetrahydrofolate reductase polymorphism, alcohol intake, and risks of colon and rectal cancers in Korea.
Colorectal Neoplasms
Methylenetetrahydrofolate reductase polymorphism, dietary interactions, and risk of colorectal cancer.
Colorectal Neoplasms
Methylenetetrahydrofolate reductase polymorphisms and colorectal cancer prognosis: A meta-analysis.
Colorectal Neoplasms
Methylenetetrahydrofolate reductase polymorphisms and risk of sporadic and hereditary colorectal cancer with or without microsatellite instability.
Colorectal Neoplasms
MTHFR 677 C>T and 1298 A>C polymorphisms and the age of onset of colorectal cancer in hereditary nonpolyposis colorectal cancer.
Colorectal Neoplasms
MTHFR and MTRR genotype and haplotype analysis and colorectal cancer susceptibility in a case-control study from the Czech Republic.
Colorectal Neoplasms
MTHFR C677T and A1298C variant genotypes and the risk of microsatellite instability among Iranian colorectal cancer patients.
Colorectal Neoplasms
MTHFR C677T and colorectal cancer risk: A meta-analysis of 25 populations.
Colorectal Neoplasms
MTHFR C677T has differential influence on risk of MSI and MSS colorectal cancer.
Colorectal Neoplasms
MTHFR C677T polymorphism and anatomopathological characteristics with prognostic significance in sporadic colorectal cancer.
Colorectal Neoplasms
MTHFR C677T polymorphism and colorectal cancer risk in Asians, a meta-analysis of 21 studies.
Colorectal Neoplasms
MTHFR C677T polymorphism contributes to colorectal cancer susceptibility: evidence from 61 case-control studies.
Colorectal Neoplasms
MTHFR C677T polymorphisms and childhood acute lymphoblastic leukemia: A meta-analysis.
Colorectal Neoplasms
MTHFR gene polymorphisms and response to chemotherapy in colorectal cancer: a meta-analysis.
Colorectal Neoplasms
MTHFR genotype and colorectal adenoma recurrence: data from a double-blind placebo-controlled clinical trial.
Colorectal Neoplasms
MTHFR Glu429Ala and ERCC5 His46His polymorphisms are associated with prognosis in colorectal cancer patients: analysis of two independent cohorts from Newfoundland.
Colorectal Neoplasms
MTHFR polymorphism, methyl-replete diets and the risk of colorectal carcinoma and adenoma among U.S. men and women: an example of gene-environment interactions in colorectal tumorigenesis.
Colorectal Neoplasms
MTHFR polymorphisms and 5-FU-based adjuvant chemotherapy in colorectal cancer.
Colorectal Neoplasms
MTHFR polymorphisms and capecitabine-induced toxicity in patients with metastatic colorectal cancer.
Colorectal Neoplasms
MTHFR polymorphisms as prognostic factors in sporadic colorectal cancer.
Colorectal Neoplasms
MTHFR rs1801133 polymorphism and susceptibility to colorectal cancer in Iranian population: evidence of a case-control study and meta-analysis.
Colorectal Neoplasms
MTHFR, MTR, and MTRR polymorphisms in relation to p16INK4A hypermethylation in mucosa of patients with colorectal cancer.
Colorectal Neoplasms
MTRR rs1801394 and its interaction with MTHFR rs1801133 in colorectal cancer: a case-control study and meta-analysis.
Colorectal Neoplasms
Nonsynonymous polymorphisms in genes in the one-carbon metabolism pathway and associations with colorectal cancer.
Colorectal Neoplasms
One-carbon metabolism and CpG island methylator phenotype status in incident colorectal cancer: a nested case-referent study.
Colorectal Neoplasms
Pharmacogenetics in cancer therapy - 8 years of experience at the Institute for Oncology and Radiology of Serbia.
Colorectal Neoplasms
Plasma folate, methylenetetrahydrofolate reductase (MTHFR), and colorectal cancer risk in three large nested case-control studies.
Colorectal Neoplasms
Plasma levels of B vitamins and colorectal cancer risk: the multiethnic cohort study.
Colorectal Neoplasms
Polymorphisms in genes involved in folate metabolism and colorectal neoplasia: a HuGE review.
Colorectal Neoplasms
Polymorphisms in genes involved in folate metabolism and plasma DNA methylation in colorectal cancer patients.
Colorectal Neoplasms
Polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene, intakes of folate and related B vitamins and colorectal cancer: a case-control study in a population with relatively low folate intake.
Colorectal Neoplasms
Polymorphisms of folate metabolism-related genes and survival of patients with colorectal cancer in the Korean population.
Colorectal Neoplasms
Polymorphisms of MTHFR C677T and A1298C associated with survival in patients with colorectal cancer treated with 5-fluorouracil-based chemotherapy.
Colorectal Neoplasms
Prediction of irinotecan and 5-fluorouracil toxicity and response in patients with advanced colorectal cancer.
Colorectal Neoplasms
Predictors of patient uptake of colorectal cancer gene environment risk assessment.
Colorectal Neoplasms
Promoter Hypermethylation of Wnt/?-catenin Signaling Pathway Inhibitor WIF-1 Gene and its Association with MTHFR C677T Polymorphism in Patients with Colorectal Cancer.
Colorectal Neoplasms
Quantitative assessment of the association between MTHFR C677T polymorphism and colorectal cancer risk in East Asians.
Colorectal Neoplasms
Quantitative proteomics reveals differentially expressed proteins in murine preneoplastic intestine in a model of intestinal tumorigenesis induced by low dietary folate and MTHFR deficiency.
Colorectal Neoplasms
Relationship between metabolic enzyme polymorphism and colorectal cancer.
Colorectal Neoplasms
Relationship between Metabolic Syndrome and MTHFR Polymorphism in Colorectal Cancer.
Colorectal Neoplasms
Relationship of the methylenetetrahydrofolate reductase C677T polymorphism with microsatellite instability and promoter hypermethylation in sporadic colorectal cancer.
Colorectal Neoplasms
Relevance of methylenetetrahydrofolate reductase gene variants C677T and A1298C with response to fluoropyrimidine-based chemotherapy in colorectal cancer: a systematic review and meta-analysis.
Colorectal Neoplasms
Risk of colorectal cancer associated with the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism in the Kashmiri population.
Colorectal Neoplasms
Role of depth of response and MTHFR genotype as predictors of fluorouracil rechallenge therapy for refractory metastatic colorectal cancer.
Colorectal Neoplasms
Role of MTHFR polymorphisms and folate levels in different phenotypes of sporadic colorectal cancers.
Colorectal Neoplasms
The 677C > T mutation in 5,10-methylenetetrahydrofolate reductase and colorectal cancer risk.
Colorectal Neoplasms
The 677C>T (rs1801133) Polymorphism in the MTHFR Gene Contributes to Colorectal Cancer Risk: A Meta-Analysis Based on 71 Research Studies.
Colorectal Neoplasms
The association between methylenetetrahydrofolate reductase polymorphism and promoter methylation in proximal colon cancer.
Colorectal Neoplasms
The folate pool in colorectal cancers is associated with DNA hypermethylation and with a polymorphism in methylenetetrahydrofolate reductase.
Colorectal Neoplasms
The Impact of Thymidylate Synthase and Methylenetetrahydrofolate Reductase Genotypes on Sensitivity to 5-Fluorouracil Treatment in Colorectal Cancer Cells.
Colorectal Neoplasms
The interactive effect of methyl-group diet and polymorphism of methylenetetrahydrofolate reductase on the risk of colorectal cancer.
Colorectal Neoplasms
The methylenetetrahydrofolate reductase (MTHFR) gene in colorectal cancer: role in tumor development and significance of allelic loss in tumor progression.
Colorectal Neoplasms
The methylenetetrahydrofolate reductase 677C-->T polymorphism as a modulator of a B vitamin network with major effects on homocysteine metabolism.
Colorectal Neoplasms
The MTHFR C677T and DeltaDNMT3B C-149T polymorphisms confer different risks for right- and left-sided colorectal cancer.
Colorectal Neoplasms
The MTHFR C677T polymorphism and colorectal cancer: the multiethnic cohort study.
Colorectal Neoplasms
The polymorphisms in methylenetetrahydrofolate reductase, methionine synthase, methionine synthase reductase, and the risk of colorectal cancer.
Colorectal Neoplasms
The reduced folate carrier (RFC1) 80G > A and folate hydrolase 1 (FOLH1) 1561C > T polymorphisms and the risk of colorectal cancer: a nested case-referent study.
Colorectal Neoplasms
The reduced folate carrier (RFC1) 80G>A and folate hydrolase 1 (FOLH1) 1561C>T polymorphisms and the risk of colorectal cancer: a nested case-referent study.
Colorectal Neoplasms
Thymidylate synthase and methylenetetrahydrofolate reductase gene polymorphisms and toxicity to capecitabine in advanced colorectal cancer patients.
Colorectal Neoplasms
Total plasma homocysteine and methylenetetrahydrofolate reductase C677T polymorphism in patients with colorectal carcinoma.
Colorectal Neoplasms
Uridine diphosphate glucuronosyl transferase 1A1 promoter polymorphism predicts the risk of gastrointestinal toxicity and fatigue induced by irinotecan-based chemotherapy.
Colorectal Neoplasms
Variant alleles in factor V, prothrombin, plasminogen activator inhibitor-1, methylenetetrahydrofolate reductase and risk of thromboembolism in metastatic colorectal cancer patients treated with first-line chemotherapy plus bevacizumab.
Colorectal Neoplasms
Variants in CDA and ABCB1 are predictors of capecitabine-related adverse reactions in colorectal cancer.
Colorectal Neoplasms
Variants in the dihydropyrimidine dehydrogenase, methylenetetrahydrofolate reductase and thymidylate synthase genes predict early toxicity of 5-fluorouracil in colorectal cancer patients.
Colorectal Neoplasms
Which gene is a dominant predictor of response during FOLFOX chemotherapy for the treatment of metastatic colorectal cancer, the MTHFR or XRCC1 gene?
Colorectal Neoplasms
[677T mutation of the MTHFR gene in adenomas and colorectal cancer in a population sample from the Northeastern Mexico. Preliminary results]
Colorectal Neoplasms
[A case-control study on the polymorphisms of methylenetetrahydrofolate reductases, drinking interaction and susceptibility in colorectal cancer]
Colorectal Neoplasms
[Association between genetic variations in methylenetetrahydrofolate reductase and risk of colorectal cancer in a Chinese population]
Colorectal Neoplasms
[Association of methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and the risk of sporadic colorectal cancer].
Colorectal Neoplasms
[Correlation between C677T and A1298C mutations of the MTHFR gene and therapeutic prognostic elements in colorectal cancer]
Colorectal Neoplasms
[Methylenetetrahydrofolate reductase polymorphisms and colorectal cancer risk: a human genomic epidemiologic review.]
Colorectal Neoplasms
[The clinical importance of methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism in the 5-fluoropyrimidine-based therapy of metastatic colorectal tumours]
Colorectal Neoplasms, Hereditary Nonpolyposis
Dietary B vitamin and methionine intake and MTHFR C677T genotype on risk of colorectal tumors in Lynch syndrome: the GEOLynch cohort study.
Colorectal Neoplasms, Hereditary Nonpolyposis
Influence of methylenetetrahydrofolate reductase gene polymorphisms C677T and A1298C on age-associated risk for colorectal cancer in a caucasian lynch syndrome population.
Colorectal Neoplasms, Hereditary Nonpolyposis
MTHFR 677 C>T and 1298 A>C polymorphisms and the age of onset of colorectal cancer in hereditary nonpolyposis colorectal cancer.
Coma
Psychosis, paraplegia and coma revealing methylenetetrahydrofolate reductase deficiency in a 56-year-old woman.
Communicable Diseases
Methylenetetrahydrofolate reductase (MTHFR) deficiency enhances resistance against cytomegalovirus infection.
Confusion
Epigenetics in Clinical Practice: Characterizing Patient and Provider Experiences with MTHFR Polymorphisms and Methylfolate.
Congenital Abnormalities
Application of kinetic polymerase chain reaction and molecular beacon assays to pooled analyses and high-throughput genotyping for candidate genes.
Congenital Abnormalities
Association between MTHFR Gene Polymorphisms and the Risk of Autism Spectrum Disorders: A Meta-Analysis.
Congenital Abnormalities
Association of folate metabolism genes MTHFR and MTRR with multiple complex congenital malformation risk in Chinese population of Shanxi.
Congenital Abnormalities
Associations between maternal methylenetetrahydrofolate reductase polymorphisms and adverse outcomes of pregnancy: the Hordaland Homocysteine Study.
Congenital Abnormalities
Endoplasmic reticulum stress increases the expression of methylenetetrahydrofolate reductase through the IRE1 transducer.
Congenital Abnormalities
Evaluation of High Resolution Melting for MTHFR C677T Genotyping in Congenital Heart Disease.
Congenital Abnormalities
Geographical and ethnic distribution of MTHFR gene polymorphisms and their associations with diseases among Chinese population.
Congenital Abnormalities
Increased Resistance to Malaria in Mice with Methylenetetrahydrofolate Reductase (Mthfr) Deficiency Suggests a Mechanism for Selection of the MTHFR 677C>T (c.665C>T) Variant.
Congenital Abnormalities
Methylenetetrahydrofolate Reductase A1298C Polymorphism and Breast Cancer Risk: A Meta-analysis of 33 Studies.
Congenital Abnormalities
Methylenetetrahydrofolate reductase deficiency and low dietary folate increase embryonic delay and placental abnormalities in mice.
Congenital Abnormalities
Methylenetetrahydrofolate reductase gene A1298C polymorphism and susceptibility to recurrent pregnancy loss: a meta-analysis.
Congenital Abnormalities
Methylenetetrahydrofolate reductase gene polymorphisms in 13 Chinese ethnic populations.
Congenital Abnormalities
Neonatal sinovenous thrombosis associated with homozygous thermolabile methylenetetrahydrofolate reductase in both mother and infant.
Congenital Abnormalities
Nucleofection is highly efficient for transfecting genes into murine embryonic palatal mesenchymal cells in primary culture.
Congenital Abnormalities
Polymorphisms in genes related to folate and cobalamin metabolism and the associations with complex birth defects.
Congenital Abnormalities
Prevalence of the methylenetetrahydrofolate reductase 677C>T polymorphism in the pregnant women of Yunnan Province, China.
Congenital Abnormalities
Role of MTHFR C677T gene polymorphism in the susceptibility of schizophrenia: An updated meta-analysis.
Congenital Abnormalities
Sex-dependent behavioral effects of Mthfr deficiency and neonatal GABA potentiation in mice.
Congenital Abnormalities
Study of four genes belonging to the folate pathway: transcobalamin 2 is involved in the onset of non-syndromic cleft lip with or without cleft palate.
Congenital Abnormalities
The association between maternal methylenetetrahydrofolate reductase C677T and A1298C polymorphism and birth defects and adverse pregnancy outcomes.
Congenital Abnormalities
The effects of diet, genetics and chemicals on toxicity and aberrant DNA methylation: an introduction.
Congenital Abnormalities
The role of FV 1691G>A, FII 20210G>A mutations and MTHFR 677C>T; 1298A>C and 103G>T FXIII gene polymorphisms in pathogenesis of intraventricular hemorrhage in infants born before 32 weeks of gestation.
Congenital Abnormalities
[Association of folate metabolism genes MTRR and MTHFR with complex congenital abnormalities among Chinese population in Shanxi Province, China].
Congenital Abnormalities
[Meta-analysis on relationship between the Chinese maternal MTHFR gene polymorphism(C677T) and neural tube defects in offspring].
Congenital Hypothyroidism
Epidemiology of rare diseases detected by newborn screening in the Czech Republic.
Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Venous thrombosis and procoagulant factors in high-risk neuroblastoma.
Coronary Artery Disease
677TT polymorphism of methylenetetrahydrofolate reductase in combination with low serum vitamin B(12) is associated with coronary in-stent restenosis.
Coronary Artery Disease
A Case-Control Study of the Association of the Polymorphisms of MTHFR and APOE with Risk Factors and the Severity of Coronary Artery Disease.
Coronary Artery Disease
A common mutation in methylenetetrahydrofolate reductase gene is not a major risk of coronary artery disease or myocardial infarction.
Coronary Artery Disease
A low prevalence of the C677T mutation in the methylenetetrahydrofolate reductase gene in Asian Indians.
Coronary Artery Disease
A mutation in the methylenetetrahydrofolate reductase gene is not associated with increased risk for coronary artery disease or myocardial infarction.
Coronary Artery Disease
A1298C methylenetetrahydrofolate reductase mutation and coronary artery disease: relationships with C677T polymorphism and homocysteine/folate metabolism.
Coronary Artery Disease
Absence of association between a common mutation in the methylenetetrahydrofolate reductase gene and the risk of coronary artery disease.
Coronary Artery Disease
Age and hypertension related changes in genotypes of MTHFR 677C>T, 1298A>C and PON1 -108C>T SNPs in men with coronary artery disease (CAD).
Coronary Artery Disease
An MTHFR variant, plasma homocysteine levels and late-onset coronary artery disease in subjects from southern Iran.
Coronary Artery Disease
Association Between MTHFR Gene Common Variants, Serum Homocysteine, and Risk of Early-Onset Coronary Artery Disease: A Case-Control Study.
Coronary Artery Disease
Association of coronary artery disease with polymorphisms of angiotensin-converting enzyme and methylenetetrahydrofolate reductase gene.
Coronary Artery Disease
Association of ESR1 (rs2234693 and rs9340799), CETP (rs708272), MTHFR (rs1801133 and rs2274976) and MS (rs185087) polymorphisms with Coronary Artery Disease (CAD).
Coronary Artery Disease
Association of genetic variants in Methylenetetrahydrofolate Reductase and Paraoxonase-1 genes with homocysteine, folate and vitamin B12 in coronary artery disease.
Coronary Artery Disease
Association of homocysteine and methylene tetrahydrofolate reductase (MTHFR C677T) gene polymorphism with coronary artery disease (CAD) in the population of North India.
Coronary Artery Disease
Association of MTRRA66G polymorphism (but not of MTHFR C677T and A1298C, MTRA2756G, TCN C776G) with homocysteine and coronary artery disease in the French population.
Coronary Artery Disease
Association of the C677T MTHFR polymorphism with homocysteine, ox-LDL levels, and thiolactonase activities in the severity of coronary syndrome.
Coronary Artery Disease
Associations of the MTHFR rs1801133 polymorphism with coronary artery disease and lipid levels: a systematic review and updated meta-analysis.
Coronary Artery Disease
C677T mutation of methylenetetrahydrofolate reductase gene and serum homocysteine levels in Turkish patients with coronary artery disease.
Coronary Artery Disease
C677T mutation of the methylenetetrahydrofolate reductase gene among the Korean infants in Seoul city.
Coronary Artery Disease
C677T polymorphism of the 5,10 MTHFR gene in young Mexican subjects with ST-elevation myocardial infarction.
Coronary Artery Disease
Cardiology patient pages. Homocysteine and MTHFR mutations: relation to thrombosis and coronary artery disease.
Coronary Artery Disease
Carrier-state of D allele in ACE gene insertion/deletion polymorphism is associated with coronary artery disease, in contrast to the C677-->T transition in the MTHFR gene.
Coronary Artery Disease
Carrier-state of two or three polymorphic variants of MTHFR, IL-6 and ICAM1 genes increases the risk of coronary artery disease.
Coronary Artery Disease
Circulating homocysteine levels in patients with type 2 diabetes mellitus.
Coronary Artery Disease
Correlation of a common mutation in the methylenetetrahydrofolate reductase gene with plasma homocysteine in patients with premature coronary artery disease.
Coronary Artery Disease
Cystathionine beta-synthase 844Ins68 polymorphism is not associated with the levels of homocysteine and cysteine in an Indian population.
Coronary Artery Disease
Dynamic regulation of MTHFR mRNA expression and C677T genotype modulate mortality in coronary artery disease patients after revascularization.
Coronary Artery Disease
Effect of common methylenetetrahydrofolate reductase gene mutation on coronary artery disease in familial hypercholesterolemia.
Coronary Artery Disease
Factor V G1691A, prothrombin G20210A and methylenetetrahydrofolate reductase polymorphism C677T are not associated with coronary artery disease and type 2 diabetes mellitus in western Iran.
Coronary Artery Disease
Factor V G1691A, prothrombin G20210A, and methylenetetrahydrofolate reductase [MTHFR] C677T gene polymorphism in angiographically documented coronary artery disease.
Coronary Artery Disease
Family history, plasma homocysteine, and age at onset of symptoms of myocardial ischemia in patients with different methylenetetrahydrofolate reductase genotypes.
Coronary Artery Disease
Frequency of MTHFR G1793A polymorphism in individuals with early coronary artery disease: cross-sectional study.
Coronary Artery Disease
Gene polymorphisms of homocysteine metabolism-related enzymes in Chinese patients with occlusive coronary artery or cerebral vascular diseases.
Coronary Artery Disease
Gene--nutrition interactions in coronary artery disease: correlation between the MTHFR C677T polymorphism and folate and homocysteine status in a Korean population.
Coronary Artery Disease
Genetic analysis of thermolabile methylenetetrahydrofolate reductase as a risk factor for myocardial infarction.
Coronary Artery Disease
Genetic interactions between MTHFR (C677T), methionine synthase (A2756G, C2758G) variants with vitamin B12 and folic acid determine susceptibility to premature coronary artery disease in Indian population.
Coronary Artery Disease
Genetic Polymorphism of Methylenetetrahydrofolate Reductase (MTHFR) and Coronary Artery Disease.
Coronary Artery Disease
Genetic polymorphism of MTHFR C677T and premature coronary artery disease susceptibility: A meta-analysis.
Coronary Artery Disease
Genetic variation of the methylenetetrahydrofolate reductase and cystathionine beta-synthase genes in Korean patients with coronary artery disease and a new polymorphism in intron 7.
Coronary Artery Disease
High plasma homocysteine is associated with the risk of coronary artery disease independent of methylenetetrahydrofolate reductase 677C-->T genotypes.
Coronary Artery Disease
Homocysteine and methylenetetrahydrofolate reductase C677T and A1298C polymorphisms in Tunisian patients with severe coronary artery disease.
Coronary Artery Disease
Homocysteine and methylenetetrahydrofolate reductase in subjects undergoing coronary angiography.
Coronary Artery Disease
Homocysteine and MTHFR and VEGF gene polymorphisms: impact on coronary artery disease.
Coronary Artery Disease
Homocysteine and the MTHFR 677C-->T allele in premature coronary artery disease. Case control and family studies.
Coronary Artery Disease
Homocysteine status and polymorphisms of methylenetetrahydrofolate reductase are not associated with restenosis after stenting in coronary arteries.
Coronary Artery Disease
Homocysteine, lipoprotein(a), and restenosis after percutaneous transluminal coronary angioplasty: a prospective study.
Coronary Artery Disease
Hyperhomocysteinaemia, methylenetetrahydrofolate reductase polymorphism and risk of coronary artery disease.
Coronary Artery Disease
Hyperhomocysteinemia and methylenetetrahydrofolate reductase polymorphism in a patient with coronary artery disease and repetitive miscarriages.
Coronary Artery Disease
Identification of six methylenetetrahydrofolate reductase (MTHFR) genotypes resulting from common polymorphisms: impact on plasma homocysteine levels and development of coronary artery disease.
Coronary Artery Disease
Identifying genetic susceptibilities to diabetes-related complications among individuals at low risk of complications: An application of tree-structured survival analysis.
Coronary Artery Disease
Impact of ethnicity and MTHFR genotype on age at onset of coronary artery disease in women in Israel.
Coronary Artery Disease
Impact of Genetic Defects on Coronary Atherosclerosis among Turkish Cypriots.
Coronary Artery Disease
Interaction among 5,10 methylenetetrahydrofolate reductase, plasminogen activator inhibitor and endothelial nitric oxide synthase gene polymorphisms predicts the severity of coronary artery disease in Turkish patients.
Coronary Artery Disease
Lack of association of methylenetetrahydrofolate reductase 677C>T mutation with coronary artery disease in a Pakistani population.
Coronary Artery Disease
Low plasma folate in combination with the 677 C-->T methylenetetrahydrofolate reductase polymorphism is associated with increased risk of coronary artery disease in Koreans.
Coronary Artery Disease
Methylenetetrahydrofolate reductase (MTHFR) 677C>T and methionine synthase reductase (MTRR) 66A>G polymorphisms: association with serum homocysteine and angiographic coronary artery disease in the era of flour products fortified with folic acid.
Coronary Artery Disease
Methylenetetrahydrofolate reductase (MTHFR) mutation, homocyst(e)ine, and coronary artery disease.
Coronary Artery Disease
Methylenetetrahydrofolate reductase C667T polymorphism is associated with increased risk of coronary artery disease in a Chinese population.
Coronary Artery Disease
Methylenetetrahydrofolate reductase C677T gene polymorphism and coronary artery disease in a Chinese Han population: a meta-analysis.
Coronary Artery Disease
Methylenetetrahydrofolate reductase C677T polymorphism is associated with increased risk of coronary artery disease in young South African Indians.
Coronary Artery Disease
Methylenetetrahydrofolate reductase gene and coronary artery disease.
Coronary Artery Disease
Methylenetetrahydrofolate reductase gene C677T and A1298C polymorphisms, plasma homocysteine, folate, and vitamin B12 levels and the extent of coronary artery disease.
Coronary Artery Disease
Methylenetetrahydrofolate reductase gene C677T polymorphism, homocysteine, vitamin B12, and DNA damage in coronary artery disease.
Coronary Artery Disease
Methylenetetrahydrofolate reductase gene polymorphism and coronary artery disease in Taiwan Chinese.
Coronary Artery Disease
Methylenetetrahydrofolate reductase gene polymorphism and its association with coronary artery disease.
Coronary Artery Disease
Methylenetetrahydrofolate reductase gene polymorphism: relation to blood pressure and cerebrovascular disease.
Coronary Artery Disease
Methylenetetrahydrofolate reductase gene, homocysteine and coronary artery disease: The A1298C polymorphism does matter. Inferences from a case study (Madeira, Portugal).
Coronary Artery Disease
Methylenetetrahydrofolate reductase genotypes and early-onset coronary artery disease.
Coronary Artery Disease
Methylenetetrahydrofolate reductase mutation (677C-->T) negatively influences plasma homocysteine response to marginal folate intake in elderly women.
Coronary Artery Disease
Methylenetetrahydrofolate reductase mutation and coronary artery disease.
Coronary Artery Disease
Methylenetetrahydrofolate reductase polymorphism (C-677T) and coronary artery disease.
Coronary Artery Disease
Methylenetetrahydrofolate Reductase Polymorphism and Premature Coronary Artery Disease.
Coronary Artery Disease
Methylenetetrahydrofolate reductase polymorphism in healthy volunteers and its correlation with homocysteine levels in patients with thrombosis.
Coronary Artery Disease
Methylenetetrahydrofolate reductase polymorphism, type II diabetes mellitus, coronary artery disease, and essential hypertension in the Czech population.
Coronary Artery Disease
Methylenetetrahydrofolate reductase TT genotype as a predictor of cardiovascular risk in hypertensive adolescents.
Coronary Artery Disease
MTHFR 677 C-->T mutation: a predictor of early-onset coronary artery disease risk.
Coronary Artery Disease
Multifactor dimensionality reduction analysis of MTHFR, PAI-1, ACE, PON1, and eNOS gene polymorphisms in patients with early onset coronary artery disease.
Coronary Artery Disease
Mutation A1298C of methylenetetrahydrofolate reductase: risk for early coronary disease not associated with hyperhomocysteinemia.
Coronary Artery Disease
Mutation C677T of methylenetetrahydrofolate reductase gene is not associated with coronary artery disease, but possibly with albuminuria, in type 2 diabetic patients.
Coronary Artery Disease
No association between MTHFR gene polymorphism and diabetic nephropathy in Japanese type II diabetic patients with proliferative diabetic retinopathy.
Coronary Artery Disease
OLR1 , PON1 and MTHFR Gene Polymorphisms, Conventional Risk Factors and the Severity of Coronary Atherosclerosis in a Chinese Han Population.
Coronary Artery Disease
Plasma homocysteine levels & 677C-->T methylenetetrahydrofolate reductase gene polymorphism in patients with coronary artery disease of different severity.
Coronary Artery Disease
Polymorphism (C677T) in the 5,10-methylenetetrahydrofolate reductase (MTHFR) gene: A preliminary study on north Indian men.
Coronary Artery Disease
Polymorphisms of methylenetetrahydrofolate reductase gene as the genetic predispositions of coronary artery diseases in eastern India.
Coronary Artery Disease
Prevalence and role of methylenetetrahydrofolate reductase 677 C-->T and 1298 A-->C polymorphisms in coronary artery disease in Arabs.
Coronary Artery Disease
Prevalence of methylenetetrahydrofolate reductase C677T and its association with arterial and venous thrombosis in the Chinese population.
Coronary Artery Disease
Recurrent Myocardial Infarction Despite Normal C-reactive Protein in a Patient with Behcet's Disease and Compound Heterozygous Methylenetetrahydrofolate Reductase (MTHFR) Mutations (C677T and A1298C).
Coronary Artery Disease
Relation between plasma homocysteine, gene polymorphisms of homocysteine metabolism-related enzymes, and angiographically proven coronary artery disease.
Coronary Artery Disease
Relation of a common methylenetetrahydrofolate reductase mutation and plasma homocysteine with intimal hyperplasia after coronary stenting.
Coronary Artery Disease
Relation of a common mutation in methylenetetrahydrofolate reductase to plasma homocysteine and early onset coronary artery disease.
Coronary Artery Disease
Role of homocysteine & MTHFR C677T gene polymorphism as risk factors for coronary artery disease in young Indians.
Coronary Artery Disease
Role of Methylenetetrahydrofolate Reductase Gene (MTHFR) 677C>T Polymorphism in Pediatric Cerebrovascular Disorders.
Coronary Artery Disease
Serum homocysteine concentrations, gemfibrozil treatment, and progression of coronary atherosclerosis.
Coronary Artery Disease
Serum homocysteine, methylenetetrahydrofolate reductase gene polymorphism and cardiovascular disease in heterozygous familial hypercholesterolemia.
Coronary Artery Disease
Sex-specific effect of the thermolabile C677T mutation in the methylenetetrahydrofolate reductase gene on angiographically assessed coronary artery disease in Brazilians.
Coronary Artery Disease
Synergistic association of DNA repair relevant gene polymorphisms with the risk of coronary artery disease in northeastern Han Chinese.
Coronary Artery Disease
The 677 C/T MTHFR polymorphism is associated with essential hypertension, coronary artery disease, and higher homocysteine levels.
Coronary Artery Disease
The C677T mutation in methylenetetrahydrofolate reductase gene, plasma homocysteine concentration and the risk of coronary artery disease.
Coronary Artery Disease
The C677T mutation in the methylenetetrahydrofolate reductase gene among the Indonesian Javanese population.
Coronary Artery Disease
The C677T mutation of the methylenetetrahydrofolate reductase gene is not associated with the risk of coronary artery disease or venous thrombosis among Chinese in Taiwan.
Coronary Artery Disease
The communal relation of MTHFR, MTR, ACE gene polymorphisms and hyperhomocysteinemia as conceivable risk of coronary artery disease.
Coronary Artery Disease
The effect of a common methylenetetrahydrofolate reductase mutation on levels of homocysteine, folate, vitamin B12 and on the risk of premature atherosclerosis.
Coronary Artery Disease
The effect of polymorphisms of MTHER gene and vitamin B on hyperhomocysteinemia.
Coronary Artery Disease
The estimation of gametic disequilibrium between DNA markers in candidate genes for coronary artery disease (CAD) and the associations of gene complexes with risk factors for CAD.
Coronary Artery Disease
The graded effect of hyperhomocysteinemia on the severity and extent of coronary atherosclerosis.
Coronary Artery Disease
The high prevalence of thermolabile 5-10 methylenetetrahydrofolate reductase (MTHFR) in Italians is not associated to an increased risk for coronary artery disease (CAD).
Coronary Artery Disease
The interaction between MTHFR 677 C-->T genotype and folate status is a determinant of coronary atherosclerosis risk.
Coronary Artery Disease
The methylenetetrahydrofolate reductase gene polymorphism in Koreans with coronary artery disease.
Coronary Artery Disease
The relationship of the methylenetetrahydrofolate reductase C677T gene polymorphism in Turkish type 2 diabetic patients with and without nephropathy.
Coronary Artery Disease
The role of genetics in coronary artery bypass surgery patients under 30 years of age.
Coronary Artery Disease
The rs1801133 polymorphism of methylenetetrahydrofolate reductase gene- the association with 5-year survival in patients with ST-elevation myocardial infarction.
Coronary Artery Disease
The TT genotype of the methylenetetrahydrofolate reductase C677T gene polymorphism is associated with the extent of coronary atherosclerosis in patients at high risk for coronary artery disease.
Coronary Artery Disease
The TT genotype of the MTHFR 677C > T polymorphism increases susceptibility to premature coronary artery disease in interaction with some of the traditional risk factors.
Coronary Artery Disease
Thermolabile defect of methylenetetrahydrofolate reductase in coronary artery disease.
Coronary Artery Disease
Thermolabile Methylenetetrahydrofolate Reductase C677T Polymorphism and Homocysteine Are Risk Factors for Coronary Artery Disease in Moroccan Population.
Coronary Artery Disease
Thermolabile methylenetetrahydrofolate reductase in coronary artery disease.
Coronary Artery Disease
Thermolabile methylenetetrahydrofolate reductase in patients with coronary artery disease.
Coronary Artery Disease
Thermolabile methylenetetrahydrofolate reductase: an inherited risk factor for coronary artery disease.
Coronary Artery Disease
[Analysis of gene complexes predisposing to coronary atherosclerosis]
Coronary Artery Disease
[Analysis of the MTHFR gene linkage disequilibrium structure and association of polymorphic gene variants with coronary atherosclerosis].
Coronary Artery Disease
[Evaluation of MTHFR C677T gene polymorphism and homocysteine level in coronary atherosclerotic disease]
Coronary Artery Disease
[Familial predisposition to ischemic cardiopathy: role of homocysteine and genetic polymorphism of methylenetetrahydrofolate reductase]
Coronary Artery Disease
[Gene Polymorphism of 5, 10-methylenetetrahydrofolate reductase as a coronary risk factor]
Coronary Artery Disease
[Relationship between polymorphism C677T of the methylene tetrahydrofolate reductase gene with clinical symptoms of coronary atherosclerosis]
Coronary Artery Disease
[Smoking enhances the decrease of adiponectin level in patients with coronary artery disease, carriers of MTHFR 677T and PON1 55M alleles].
Coronary Disease
5,10-methylenetetrahydrofolate reductase C677T gene polymorphism and peripheral arterial disease: A meta-analysis.
Coronary Disease
A common mutation in the methylenetetrahydrofolate reductase gene and risk of coronary heart disease: results among U.S. men.
Coronary Disease
An integrated approach to the meta-analysis of genetic association studies using Mendelian randomization.
Coronary Disease
Apolipoprotein E and methylenetetrahydrofolate reductase genetic polymorphisms in relation to other risk factors for cardiovascular disease in UK Caucasians and Black South Africans.
Coronary Disease
Detection of C677T mutation of MTHFR in subject with coronary heart disease by hairpin probe with enzymatic color on microarray.
Coronary Disease
Distribution in healthy and coronary populations of the methylenetetrahydrofolate reductase (MTHFR) C677T mutation.
Coronary Disease
Homocysteine and Coronary Heart Disease: Meta-analysis of MTHFR Case-Control Studies, Avoiding Publication Bias.
Coronary Disease
Homocysteine and methylenetetrahydrofolate reductase genotype: association with risk of coronary heart disease and relation to inflammatory, hemostatic, and lipid parameters.
Coronary Disease
Hyperhomocyst(e)inemia, MTHFR 677C-->T polymorphism and folate status in acute coronary disease.
Coronary Disease
Hyperhomocysteinemia, MTHFR C677T genotype and low folate levels: a risk combination for acute coronary disease in a Portuguese population.
Coronary Disease
Improved real-time multiplex polymerase chain reaction detection of methylenetetrahydrofolate reductase (MTHFR) 677C>T and 1298A>C polymorphisms using nearest neighbor model-based probe design.
Coronary Disease
Interaction between Mediterranean diet and methylenetetrahydrofolate reductase C677T mutation on oxidized low density lipoprotein concentrations: The ATTICA study.
Coronary Disease
Large scale association analysis for identification of genes underlying premature coronary heart disease: cumulative perspective from analysis of 111 candidate genes.
Coronary Disease
Meta-analysis of MTHFR 677C->T polymorphism and coronary heart disease: does totality of evidence support causal role for homocysteine and preventive potential of folate?
Coronary Disease
Methylene tetrahydrofolate reductase (MTHFR) and nitric oxide synthase (ecNOS) genes and risks of peripheral arterial disease and coronary heart disease: Edinburgh Artery Study.
Coronary Disease
Methylenetetrahydrofolate reductase 677 C-->T mutation and coronary heart disease risk in UK Indian Asians.
Coronary Disease
Methylenetetrahydrofolate reductase and apolipoprotein E polymorphisms are independent risk factors for coronary heart disease in Japanese: a case-control study.
Coronary Disease
Methylenetetrahydrofolate reductase gene mutation and hyperhomocysteinemia as a risk factor for coronary heart disease in the Indian population.
Coronary Disease
Methylenetetrahydrofolate Reductase Gene Polymorphism C677T is Associated with Increased Risk of Coronary Heart Disease in Chinese Type 2 Diabetic Patients.
Coronary Disease
Methylenetetrahydrofolate reductase polymorphism 677C>T is associated with peripheral arterial disease in type 2 diabetes.
Coronary Disease
Methylenetetrahydrofolate reductase polymorphism associated with susceptibility to coronary heart disease in Chinese type 2 diabetic patients.
Coronary Disease
MTHFR 677C-->T polymorphism and risk of coronary heart disease: a meta-analysis.
Coronary Disease
MTHFR C677T Polymorphism and Serum Homocysteine Level as Risk Factors of Coronary Heart Disease in Patients with Androgenetic Alopecia: A Case Control Study.
Coronary Disease
Mutation A1298C of methylenetetrahydrofolate reductase: risk for early coronary disease not associated with hyperhomocysteinemia.
Coronary Disease
Relationship between two sequence variations in the gene for peroxisome proliferator-activated receptor-gamma and plasma homocysteine concentration. Health in men study.
Coronary Disease
The APOE E4 Allele Confers Increased Risk of Ischemic Stroke Among Greek Carriers.
Coronary Disease
The association between plasma homocysteine and coronary heart disease is modified by the MTHFR 677C>T polymorphism.
Coronary Disease
The association of MTHFR C677T gene variants and lipid profiles or body mass index in patients with diabetic and nondiabetic coronary heart disease.
Coronary Disease
The effects of folic acid supplementation on plasma total homocysteine are modulated by multivitamin use and methylenetetrahydrofolate reductase genotypes.
Coronary Disease
The human MTHFR rs4846049 polymorphism increases coronary heart disease risk through modifying miRNA binding.
Coronary Disease
The methylenetetrahydrofolate reductase gene polymorphism (C677T) is associated with increased cardiovascular mortality in Hungary.
Coronary Disease
[Association of methylenetetrahydrofolate reductase gene polymorphism with the development of myocardial infarction in patients with type 2 diabetes].
Coronary Disease
[C677T genetic polymorphism of methylenetetrahydrofolate reductase in premature coronary heart disease]
Coronary Disease
[Genetic polymorphisms of homocysteine metabolism related enzymes in patients with coronary heart disease]
Coronary Disease
[Levels of homocysteine and polymorphisms of homocysteine metabolism-related enzymes in patients with type 2 diabetes mellitus and coronary heart disease]
Coronary Disease
[Relationship between methylenetetrahydrofolate reductase gene polymorphism and coronary heart disease]
Coronary Disease
[Study on the relationship between methylenetetrahydrofolate reductase gene C677T mutation and coronary heart disease]
Coronary Stenosis
Prevalence of methylenetetrahydrofolate reductase C677T and its association with arterial and venous thrombosis in the Chinese population.
Coronary Stenosis
Thermolabile defect of methylenetetrahydrofolate reductase in coronary artery disease.
Coronary Stenosis
[Effect of polymorphisms on key enzymes in homocysteine metabolism, on plasma homocysteine level and on coronary artery-disease risk in a Tunisian population]
Coronary Thrombosis
Myocardial Infarction in a Newborn Heterozygous for the MTHFR C677T Mutation.
COVID-19
COVID-19 spreading across world correlates with C677T allele of the methylenetetrahydrofolate reductase (MTHFR) gene prevalence.
Craniosynostoses
Methylenetetrahydrofolate reductase C677T variant in Indian children with craniosynostosis: Its role in the pathogenesis, risk of craniosynostosis.
Crohn Disease
Anterior ischemic optic neuropathy in a patient with Crohn's disease and aberrant MTHFR and GPIIIa gene variants.
Crohn Disease
High prevalence of combined thrombophilic abnormalities in patients with inflammatory bowel disease.
Crohn Disease
Methylenetetrahydrofolate reductase C677T variant in Moroccan patients with inflammatory bowel disease.
Crohn Disease
The association of the MTHFR C677T polymorphism with inflammatory bowel diseases in the Israeli Jewish population: An example of genetic heterogeneity.
cystathionine beta-synthase deficiency
Homozygous cystathionine beta-synthase deficiency, combined with factor V Leiden or thermolabile methylenetetrahydrofolate reductase in the risk of venous thrombosis.
cystathionine beta-synthase deficiency
Impact of new mutations in the methylenetetrahydrofolate reductase gene assessed on biochemical phenotypes: a familial study.
cystathionine beta-synthase deficiency
Molecular and clinical characterisation of homocystinuria in two Austrian families with cystathionine beta-synthase deficiency.
cystathionine beta-synthase deficiency
Newborn screening for homocystinurias and methylation disorders: systematic review and proposed guidelines.
cystathionine beta-synthase deficiency
Newborn screening for homocystinurias: recent recommendations versus current practice.
cystathionine beta-synthase deficiency
Newborn screening for homocystinurias: Recent recommendations versus current practice.
cystathionine beta-synthase deficiency
Pathogenicity of thermolabile methylenetetrahydrofolate reductase for vascular dementia.
cystathionine beta-synthase deficiency
The Effect of in Vitro Homocystinuria on the Suckling Rat Hippocampal Acetylcholinesterase.
cystathionine beta-synthase deficiency
The effect of in vitro homocystinuria on the suckling rat hippocampal acetylcholinesterase.
cystathionine beta-synthase deficiency
[Cystathionine betasynthase and MTHFR deficiencies in adults]
cystathionine gamma-synthase deficiency
Genetic and nongenetic factors for moderate hyperhomocyst(e)inemia.
cystathionine gamma-synthase deficiency
Treatment of hyperhomocyst(e)inemia: physiological basis.
cystathionine gamma-synthase deficiency
[Hyperhomocysteinemia--a risk factor for development of occlusive vascular diseases]
Cystic Fibrosis
Epidemiology of rare diseases detected by newborn screening in the Czech Republic.
Cysts
MTHFR homozygous mutation and additional risk factors for cerebral infarction in a large Italian family.
Cytomegalovirus Infections
Methylenetetrahydrofolate reductase (MTHFR) deficiency enhances resistance against cytomegalovirus infection.
Dementia
ACE, MTHFR, factor V Leiden, and APOE polymorphisms in patients with vascular and Alzheimer's dementia.
Dementia
Analysis of alpha-1 antichymotrypsin, presenilin-1, angiotensin-converting enzyme, and methylenetetrahydrofolate reductase loci as candidates for dementia.
Dementia
Association of IL-1 RN*2 allele and methionine synthase 2756 AA genotype with dementia severity of sporadic Alzheimer's disease.
Dementia
Association of MTHFR C677T polymorphism with loneliness but not depression in cognitively normal elderly males.
Dementia
Heterozygote advantage of the MTHFR C677T polymorphism on specific cognitive performance in elderly Chinese males without dementia.
Dementia
Moderately elevated plasma homocysteine, methylenetetrahydrofolate reductase genotype, and risk for stroke, vascular dementia, and Alzheimer disease in Northern Ireland.
Dementia
MTHFR and ACE gene polymorphisms and risk of vascular and degenerative dementias in the elderly.
Dementia
MTHFR Gene Mutations Correlate with White Matter Disease Burden and Predict Cerebrovascular Disease and Dementia.
Dementia
Plasma homocysteine and MTHFRC677T polymorphism as risk factors for incident dementia.
Dementia
Plasma total homocysteine levels and the C677T mutation in the methylenetetrahydrofolate reductase (MTHFR) gene: a study in an Italian population with dementia.
Dementia
The active site of oxidative phosphorylation and the origin of hyperhomocysteinemia in aging and dementia.
Dementia
The Different Relationship between Homocysteine and Uric Acid Levels with Respect to the MTHFR C677T Polymorphism According to Gender in Patients with Cognitive Impairment.
Dementia
The sex-specific effect of the apolipoprotein E allele and methylenetetrahydrofolate reductase gene polymorphism on the biochemical, anatomical, and cognitive profiles of patients clinically diagnosed with probable Alzheimer's disease.
Dementia
Thermolabile methylenetetrahydrofolate reductase gene and the risk of cognitive impairment in those over 85.
Dementia, Vascular
Apolipoprotein E, methylenetetrahydrofolate reductase (MTHFR) mutation and the risk of senile dementia--an epidemiological study using the polymerase chain reaction (PCR) method.
Dementia, Vascular
Association Between MTHFR Gene Polymorphisms, Smoking, and the Incidence of Vascular Dementia.
Dementia, Vascular
Common polymorphisms in methylenetetrahydrofolate reductase (MTHFR): relationships with plasma homocysteine concentrations and cognitive status in elderly northern italian subjects.
Dementia, Vascular
Genetic polymorphisms in older subjects with vascular or Alzheimer's dementia.
Dementia, Vascular
Moderately elevated plasma homocysteine, methylenetetrahydrofolate reductase genotype, and risk for stroke, vascular dementia, and Alzheimer disease in Northern Ireland.
Dementia, Vascular
MTHFR (677 and 1298) and IL-6-174 G/C genes in pathogenesis of Alzheimer's and vascular dementia and their epistatic interaction.
Dementia, Vascular
Pathogenicity of thermolabile methylenetetrahydrofolate reductase for vascular dementia.
Dementia, Vascular
The C677T methylenetetrahydrofolate reductase mutation is not associated with Alzheimer's disease.
Dementia, Vascular
The C677T mutation in the methylenetetrahydrofolate reductase (MTHFR) gene and vascular dementia.
Dementia, Vascular
The MTHFR C677T polymorphism contributes to an increased risk for vascular dementia: A meta-analysis.
Demyelinating Diseases
Hydrocephalus internus in two patients with 5,10-methylenetetrahydrofolate reductase deficiency.
Depression, Postpartum
Folic acid supplementation during pregnancy may protect against depression 21 months after pregnancy, an effect modified by MTHFR C677T genotype.
Dermatitis, Atopic
High Circulating Folate and Vitamin B-12 Concentrations in Women During Pregnancy Are Associated with Increased Prevalence of Atopic Dermatitis in Their Offspring.
Diabetes Complications
Association of MTHFR C677T polymorphism and type 2 diabetes mellitus (T2DM) susceptibility.
Diabetes Complications
Is the C677T polymorphism in methylenetetrahydrofolate reductase gene or plasma homocysteine a risk factor for diabetic peripheral neuropathy in Chinese individuals?
Diabetes Complications
Methylenetetrahydrofolate reductase polymorphism 677C>T is associated with peripheral arterial disease in type 2 diabetes.
Diabetes Complications
Thermolabile methylenetetrahydrofolate reductase enzyme genotype is frequent in type 2 diabetic patients with normal fasting homocysteine levels.
Diabetes Mellitus
A study on the correlation between MTHFR promoter methylation and diabetic nephropathy.
Diabetes Mellitus
Association between folate metabolism-related polymorphisms and colorectal cancer risk.
Diabetes Mellitus
Association Between Homocysteine Level and Methylenetetrahydrofolate Reductase Gene Polymorphisms in Type 2 Diabetes Accompanied by Dyslipidemia.
Diabetes Mellitus
Association between MTHFR C677T polymorphism and diabetic nephropathy or diabetes mellitus risk: need for clarification of data in a recent meta-analysis.
Diabetes Mellitus
Association of ACE and MTHFR genetic polymorphisms with type 2 diabetes mellitus: Susceptibility and complications.
Diabetes Mellitus
Association of gene polymorphisms with myocardial infarction in individuals with or without conventional coronary risk factors.
Diabetes Mellitus
Association of genetic polymorphism of PPAR?-2, ACE, MTHFR, FABP-2 and FTO genes in risk prediction of type 2 diabetes mellitus.
Diabetes Mellitus
Association of MTHFR and PPAR?2 gene polymorphisms in relation to type 2 diabetes mellitus cases among north Indian population.
Diabetes Mellitus
Association of MTHFR C677T polymorphism and type 2 diabetes mellitus (T2DM) susceptibility.
Diabetes Mellitus
Association of plasma homocysteine with serum interleukin-6 and C-peptide levels in patients with type 2 diabetes.
Diabetes Mellitus
Association of polymorphism of methylene-tetrahydro-folate-reductase with urinary albumin excretion rate in type 1 diabetes mellitus but not with preeclampsia, retinopathy, and preterm delivery.
Diabetes Mellitus
Association of tagging SNPs in the MTHFR gene with risk of type 2 diabetes mellitus and serum homocysteine levels in a Chinese population.
Diabetes Mellitus
Association of the C677T Polymorphism in the Human Methylenetetrahydrofolate Reductase (MTHFR) Gene with the Genetic Predisposition for Type 2 Diabetes Mellitus in a Moroccan Population.
Diabetes Mellitus
Blood S-adenosylmethionine concentrations and lymphocyte methylenetetrahydrofolate reductase activity in diabetes mellitus and diabetic nephropathy.
Diabetes Mellitus
Does the MTHFR C677T gene polymorphism indicate cardiovascular disease risk in type 2 diabetes mellitus patients?
Diabetes Mellitus
Factor V G1691A, prothrombin G20210A and methylenetetrahydrofolate reductase polymorphism C677T are not associated with coronary artery disease and type 2 diabetes mellitus in western Iran.
Diabetes Mellitus
Genetic polymorphism of 5,10-methylenetetrahydrofolate increases risk of myocardial infarction and is correlated to elevated levels of homocysteine in the Japanese general population.
Diabetes Mellitus
Genetic Predisposition for Development of Nephropathy in Type 2 Diabetes Mellitus.
Diabetes Mellitus
Genetic risk for atherothrombotic cerebral infarction in individuals stratified by sex or conventional risk factors for atherosclerosis.
Diabetes Mellitus
Hyperhomocysteinemia and elevated ox-LDL in Tunisian type 2 diabetic patients: role of genetic and dietary factors.
Diabetes Mellitus
Impaired Placentation and Early Pregnancy Loss in Patients with MTHFR Polymorphisms and Type-1 Diabetes Mellitus.
Diabetes Mellitus
Interaction of eNOS polymorphism with MTHFR variants increase the risk of diabetic nephropathy and its progression in type 2 diabetes mellitus patients.
Diabetes Mellitus
Interaction of MTHFR C677T polymorphism with smoking in susceptibility to diabetic nephropathy in Chinese men with type 2 diabetes.
Diabetes Mellitus
Is the C677T Polymorphism in Methylenetetrahydrofolate Reductase Gene a Risk Factor for Diabetic Nephropathy or Diabetes Mellitus in a Chinese Population?
Diabetes Mellitus
Methylene tetrahydrofolate reductase C677T mutation and left ventricular hypertrophy in Turkish patients with type II diabetes mellitus.
Diabetes Mellitus
Methylenetetrahydrofolate Reductase (MTHFR) (C677T and A1298C) Polymorphisms and Vascular Complications in Patients with Type 2 Diabetes.
Diabetes Mellitus
Methylenetetrahydrofolate reductase (MTHFR) C677T gene polymorphism and diabetic nephropathy susceptibility in patients with type 2 diabetes mellitus.
Diabetes Mellitus
Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and susceptibility to diabetic nephropathy in Chinese type 2 diabetic patients: a meta-analysis.
Diabetes Mellitus
Methylenetetrahydrofolate reductase C677T polymorphism and type 2 diabetes mellitus in Chinese population: a meta-analysis of 29 case-control studies.
Diabetes Mellitus
Methylenetetrahydrofolate reductase gene polymorphism and risk of premature myocardial infarction.
Diabetes Mellitus
Methylenetetrahydrofolate reductase gene polymorphism and risk of type 2 diabetes mellitus.
Diabetes Mellitus
Methylenetetrahydrofolate reductase gene polymorphism, homocysteine and risk of macroangiopathy in Type 2 diabetes mellitus.
Diabetes Mellitus
Methylenetetrahydrofolate reductase polymorphism (C677T), hyperhomocysteinemia, and risk of ischemic cardiovascular disease and venous thromboembolism: prospective and case-control studies from the Copenhagen City Heart Study.
Diabetes Mellitus
Methylenetetrahydrofolate reductase polymorphism, type II diabetes mellitus, coronary artery disease, and essential hypertension in the Czech population.
Diabetes Mellitus
MTHFR (Ala 222 Val) polymorphism and AMI in patients with type II diabetes mellitus.
Diabetes Mellitus
Peripheral Vascular Disease Susceptibility Based on Diabetes Mellitus and rs17367504 Polymorphism of the MTHFR Gene.
Diabetes Mellitus
Physical Activity Level Influences MTHFR Gene Methylation Profile in Diabetic Patients.
Diabetes Mellitus
Plasma homocysteine, methylenetetrahydrofolate reductase gene polymorphism and carotid intima-media thickness in Italian type 2 diabetic patients.
Diabetes Mellitus
Plasma total homocysteine levels and methylenetetrahydrofolate reductase gene polymorphism in patients with type 2 diabetes mellitus.
Diabetes Mellitus
Polymorphism in methylenetetrahydrofolate reductase gene: its impact on plasma homocysteine levels and carotid atherosclerosis in ESRD patients receiving hemodialysis.
Diabetes Mellitus
Polymorphism of the methylenetetrahydrofolate reductase gene association with homocysteine and ischemic stroke in type 2 diabetes.
Diabetes Mellitus
Prevalence of methylenetetrahydrofolate reductase C677T and A1298C polymorphisms in Taiwanese patients with Type 2 diabetic mellitus.
Diabetes Mellitus
Relationship between genetic polymorphisms of angiotensin-converting enzyme and methylenetetrahydrofolate reductase as risk factors for type 2 diabetes in Tunisian patients.
Diabetes Mellitus
Relationship between MTHFR C677T and A1298C gene polymorphisms and complications of type 2 diabetes mellitus in an Emirati population.
Diabetes Mellitus
Reply: Is the C677T Polymorphism in Methylenetetrahydrofolate Reductase Gene a Risk Factor for Diabetic Nephropathy or Diabetes Mellitus in a Chinese Population?
Diabetes Mellitus
Role of treatment-modifying MTHFR677C>T and 1298A>C polymorphisms in metformin-treated Puerto Rican patients with type-2 diabetes mellitus and peripheral neuropathy.
Diabetes Mellitus
Screening the single nucleotide polymorphisms in patients with internal carotid artery stenosis by oligonucleotide-based custom DNA array.
Diabetes Mellitus
Synergistic effects of the MTHFR C677T and A1298C polymorphisms on the increased risk of micro- and macro-albuminuria and progression of diabetic nephropathy among Iranians with type 2 diabetes mellitus.
Diabetes Mellitus
The association between end-stage diabetic nephropathy and methylenetetrahydrofolate reductase genotype with macroangiopathy in type 2 diabetes mellitus.
Diabetes Mellitus
The association between two common mutations C677T and A1298C in human methylenetetrahydrofolate reductase gene and the risk for diabetic nephropathy in type II diabetic patients.
Diabetes Mellitus
The C677T methylenetetrahydrofolate reductase gene mutation and nephropathy in type 2 diabetes mellitus.
Diabetes Mellitus
The common mutations C677T and A1298C in the human methylenetetrahydrofolate reductase gene are associated with hyperhomocysteinemia and cardiovascular disease in hemodialysis patients.
Diabetes Mellitus
The effect of MTHFR C677T polymorphism on type 2 diabetes mellitus with vascular complications in Chinese Han population: a meta-analysis.
Diabetes Mellitus
The relationship between methylenetetrahydrofolate reductase C677T gene polymorphism and diabetic nephropathy in Croatian type 2 diabetic patients.
Diabetes Mellitus
The relationship between MTHFR gene polymorphisms, plasma homocysteine levels and diabetic retinopathy in type 2 diabetes mellitus.
Diabetes Mellitus
The relationship between of ACE I/D and the MTHFR C677T polymorphisms in the pathophysiology of type 2 diabetes mellitus in a population of Brazilian obese patients.
Diabetes Mellitus
Thermolabile methylenetetrahydrofolate reductase enzyme genotype is frequent in type 2 diabetic patients with normal fasting homocysteine levels.
Diabetes Mellitus
[Levels of homocysteine and polymorphisms of homocysteine metabolism-related enzymes in patients with type 2 diabetes mellitus and coronary heart disease]
Diabetes Mellitus
[Relationship between methylenetrahydrofolate reductase gene and ischemic stroke]
Diabetes Mellitus
[The abnormal reaction to post methionine loading test in type diabetes with or without retinopathy]
Diabetes Mellitus
[The association of methylenetetrahydrofolate reductase gene polymorphism with nephropathy in type 2 diabetes mellitus in Chinese]
Diabetes Mellitus
[The relationship of methylenetetrahydrofolate reductase gene polymorphism and plasma homocysteine levels in type 2 diabetes mellitus patients with diabetic retinopathy]
Diabetes Mellitus, Type 1
Association of polymorphism of methylene-tetrahydro-folate-reductase with urinary albumin excretion rate in type 1 diabetes mellitus but not with preeclampsia, retinopathy, and preterm delivery.
Diabetes Mellitus, Type 1
Methylenetetrahydrofolate reductase and methionine synthase reductase gene polymorphisms and protection from microvascular complications in adolescents with type 1 diabetes.
Diabetes Mellitus, Type 1
Methylenetetrahydrofolate reductase gene polymorphism and susceptibility to diabetic nephropathy in type 1 diabetes.
Diabetes Mellitus, Type 1
Methylenetetrahydrofolate reductase gene polymorphism as a risk factor for diabetic nephropathy in IDDM patients.
Diabetes Mellitus, Type 1
MTHFR gene polymorphism and diabetic nephropathy in type 1 diabetes.
Diabetes Mellitus, Type 1
Plasma total homocysteine levels in children with type 1 diabetes: relationship with vitamin status, methylene tetrahydrofolate reductase genotype, disease parameters and coronary risk factors.
Diabetes Mellitus, Type 1
Reduced total plasma homocyst(e)ine in children and adolescents with type 1 diabetes.
Diabetes Mellitus, Type 2
ACE I/D and MTHFR C677T polymorphisms are significantly associated with type 2 diabetes in Arab ethnicity: A meta-analysis.
Diabetes Mellitus, Type 2
Additive Interaction of MTHFR C677T and MTRR A66G Polymorphisms with Being Overweight/Obesity on the Risk of Type 2 Diabetes.
Diabetes Mellitus, Type 2
Association between ACE (rs4646994), FABP2 (rs1799883), MTHFR (rs1801133), FTO (rs9939609) Genes Polymorphism and Type 2 Diabetes with Dyslipidemia.
Diabetes Mellitus, Type 2
Association between Genetic Variants and Diabetes Mellitus in Iranian Populations: A Systematic Review of Observational Studies.
Diabetes Mellitus, Type 2
Association Between Homocysteine Level and Methylenetetrahydrofolate Reductase Gene Polymorphisms in Type 2 Diabetes Accompanied by Dyslipidemia.
Diabetes Mellitus, Type 2
Association of ACE and MTHFR genetic polymorphisms with type 2 diabetes mellitus: Susceptibility and complications.
Diabetes Mellitus, Type 2
Association of genetic polymorphism of PPAR?-2, ACE, MTHFR, FABP-2 and FTO genes in risk prediction of type 2 diabetes mellitus.
Diabetes Mellitus, Type 2
Association of Kaphaja and Kapha-Pittaja Prakriti and methylenetetrahydrofolate reductase C677T allele with type 2 diabetes.
Diabetes Mellitus, Type 2
Association of methylenetetrahydrofolate reductase gene polymorphism with carotid arterial wall thickening and myocardial infarction risk in NIDDM.
Diabetes Mellitus, Type 2
Association of MTHFR and PPAR?2 gene polymorphisms in relation to type 2 diabetes mellitus cases among north Indian population.
Diabetes Mellitus, Type 2
Association of MTHFR C677T polymorphism and type 2 diabetes mellitus (T2DM) susceptibility.
Diabetes Mellitus, Type 2
Association of tagging SNPs in the MTHFR gene with risk of type 2 diabetes mellitus and serum homocysteine levels in a Chinese population.
Diabetes Mellitus, Type 2
Association of the C677T Polymorphism in the Human Methylenetetrahydrofolate Reductase (MTHFR) Gene with the Genetic Predisposition for Type 2 Diabetes Mellitus in a Moroccan Population.
Diabetes Mellitus, Type 2
Association of Two Methylenetetrahydrofolate Reductase Polymorphisms (rs1801133, rs1801131) with the Risk of Type 2 Diabetes in South-East of Iran.
Diabetes Mellitus, Type 2
Differential contribution of MTHFR C677T variant to the risk of diabetic nephropathy in Lebanese and Bahraini Arabs.
Diabetes Mellitus, Type 2
Does the MTHFR C677T gene polymorphism indicate cardiovascular disease risk in type 2 diabetes mellitus patients?
Diabetes Mellitus, Type 2
Effect of MTHFR C677T genotype on survival in type 2 diabetes patients with end-stage diabetic nephropathy.
Diabetes Mellitus, Type 2
Effects of the C677T and A1298C polymorphisms of the MTHFR gene on the genetic predisposition for diabetic nephropathy.
Diabetes Mellitus, Type 2
Factor V G1691A, prothrombin G20210A and methylenetetrahydrofolate reductase polymorphism C677T are not associated with coronary artery disease and type 2 diabetes mellitus in western Iran.
Diabetes Mellitus, Type 2
Genetic Predisposition for Development of Nephropathy in Type 2 Diabetes Mellitus.
Diabetes Mellitus, Type 2
Hyperhomocysteinemia and elevated ox-LDL in Tunisian type 2 diabetic patients: role of genetic and dietary factors.
Diabetes Mellitus, Type 2
Impact of KCNJ11 rs5219, UCP2 rs659366, and MTHFR rs1801133 Polymorphisms on Type 2 Diabetes: A Cross-Sectional Study.
Diabetes Mellitus, Type 2
Interaction of eNOS polymorphism with MTHFR variants increase the risk of diabetic nephropathy and its progression in type 2 diabetes mellitus patients.
Diabetes Mellitus, Type 2
Interaction of MTHFR C677T polymorphism with smoking in susceptibility to diabetic nephropathy in Chinese men with type 2 diabetes.
Diabetes Mellitus, Type 2
Kaphaja, Kapha-Pittaja Prakriti, methylenetetrahydrofolate reductase C677T allele and type 2 diabetes.
Diabetes Mellitus, Type 2
Lack of association between carotid intima-media thickness and methylenetetrahydrofolate reductase gene polymorphism or serum homocysteine in non-insulin-dependent diabetes mellitus.
Diabetes Mellitus, Type 2
Methylenetetrahydrofolate Reductase (MTHFR) (C677T and A1298C) Polymorphisms and Vascular Complications in Patients with Type 2 Diabetes.
Diabetes Mellitus, Type 2
Methylenetetrahydrofolate reductase (MTHFR) C677T gene polymorphism and diabetic nephropathy susceptibility in patients with type 2 diabetes mellitus.
Diabetes Mellitus, Type 2
Methylenetetrahydrofolate reductase C677T polymorphism and type 2 diabetes mellitus in Chinese population: a meta-analysis of 29 case-control studies.
Diabetes Mellitus, Type 2
Methylenetetrahydrofolate reductase gene polymorphism and risk of type 2 diabetes mellitus.
Diabetes Mellitus, Type 2
Methylenetetrahydrofolate reductase gene polymorphism as a risk factor for diabetic nephropathy in NIDDM patients.
Diabetes Mellitus, Type 2
Methylenetetrahydrofolate reductase gene polymorphism, homocysteine and risk of macroangiopathy in Type 2 diabetes mellitus.
Diabetes Mellitus, Type 2
Methylenetetrahydrofolate reductase polymorphism 677C>T is associated with peripheral arterial disease in type 2 diabetes.
Diabetes Mellitus, Type 2
Mild hyperhomocysteinemia, C677T polymorphism on methylenetetrahydrofolate reductase gene and the risk of macroangiopathy in type 2 diabetes: a prospective study.
Diabetes Mellitus, Type 2
MTHFR 677T variant contributes to diabetic nephropathy risk in Caucasian individuals with type 2 diabetes: A meta-analysis.
Diabetes Mellitus, Type 2
MTHFR C677T and A1298C gene polymorphisms and hyperhomocysteinemia as risk factors of diabetic nephropathy in type 2 diabetes patients.
Diabetes Mellitus, Type 2
MTHFR C677T, A1298C and ACE I/D polymorphisms as risk factors for diabetic nephropathy among type 2 diabetic patients.
Diabetes Mellitus, Type 2
MTHFR gene C677T polymorphism and type 2 diabetic nephropathy in Asian populations: a meta-analysis.
Diabetes Mellitus, Type 2
MTHFR gene polymorphism as an exacerbation factor of diabetic nephropathy in type 2 diabetes. Analysis in Japanese male hemodialysis patients.
Diabetes Mellitus, Type 2
Mutation C677T of methylenetetrahydrofolate reductase gene is not associated with coronary artery disease, but possibly with albuminuria, in type 2 diabetic patients.
Diabetes Mellitus, Type 2
Physical Activity Level Influences MTHFR Gene Methylation Profile in Diabetic Patients.
Diabetes Mellitus, Type 2
Plasma homocysteine, methylenetetrahydrofolate reductase gene polymorphism and carotid intima-media thickness in Italian type 2 diabetic patients.
Diabetes Mellitus, Type 2
Plasma total homocysteine levels and methylenetetrahydrofolate reductase gene polymorphism in patients with type 2 diabetes mellitus.
Diabetes Mellitus, Type 2
Polymorphism of the methylenetetrahydrofolate reductase gene association with homocysteine and ischemic stroke in type 2 diabetes.
Diabetes Mellitus, Type 2
Prevalence of methylenetetrahydrofolate reductase C677T and A1298C polymorphisms in Taiwanese patients with Type 2 diabetic mellitus.
Diabetes Mellitus, Type 2
Relationship between genetic polymorphisms of angiotensin-converting enzyme and methylenetetrahydrofolate reductase as risk factors for type 2 diabetes in Tunisian patients.
Diabetes Mellitus, Type 2
Relationship between MTHFR C677T and A1298C gene polymorphisms and complications of type 2 diabetes mellitus in an Emirati population.
Diabetes Mellitus, Type 2
Serum homocysteine, MTHFR gene polymorphism, and carotid intimal-medial thickness in NIDDM subjects.
Diabetes Mellitus, Type 2
Synergistic effects of the MTHFR C677T and A1298C polymorphisms on the increased risk of micro- and macro-albuminuria and progression of diabetic nephropathy among Iranians with type 2 diabetes mellitus.
Diabetes Mellitus, Type 2
The association between end-stage diabetic nephropathy and methylenetetrahydrofolate reductase genotype with macroangiopathy in type 2 diabetes mellitus.
Diabetes Mellitus, Type 2
The association between two common mutations C677T and A1298C in human methylenetetrahydrofolate reductase gene and the risk for diabetic nephropathy in type II diabetic patients.
Diabetes Mellitus, Type 2
The C677T methylenetetrahydrofolate reductase gene mutation and nephropathy in type 2 diabetes mellitus.
Diabetes Mellitus, Type 2
The effect of MTHFR C677T polymorphism on type 2 diabetes mellitus with vascular complications in Chinese Han population: a meta-analysis.
Diabetes Mellitus, Type 2
The MTHFR CT polymorphism confers a high risk for stroke in both homozygous and heterozygous T allele carriers with Type 2 diabetes.
Diabetes Mellitus, Type 2
The relationship between C677T methylenetetrahydrofolate reductase gene polymorphism and retinopathy in type 2 diabetes: a meta-analysis.
Diabetes Mellitus, Type 2
The relationship between MTHFR gene polymorphisms, plasma homocysteine levels and diabetic retinopathy in type 2 diabetes mellitus.
Diabetes Mellitus, Type 2
The relationship between of ACE I/D and the MTHFR C677T polymorphisms in the pathophysiology of type 2 diabetes mellitus in a population of Brazilian obese patients.
Diabetes Mellitus, Type 2
Thermolabile methylenetetrahydrofolate reductase enzyme genotype is frequent in type 2 diabetic patients with normal fasting homocysteine levels.
Diabetes Mellitus, Type 2
[Association of methylenetetrahydrofolate reductase gene polymorphism with the development of myocardial infarction in patients with type 2 diabetes].
Diabetes Mellitus, Type 2
[Effects of methylenetetrahydrofolate reductase gene polymorphism and long-term exposure to organophosphorus pesticides on type 2 diabetes mellitus].
Diabetes Mellitus, Type 2
[Levels of homocysteine and polymorphisms of homocysteine metabolism-related enzymes in patients with type 2 diabetes mellitus and coronary heart disease]
Diabetes Mellitus, Type 2
[Methylenetetrahydrofolate reductase gene polymorphism in patients with type 2 diabetes]
Diabetes Mellitus, Type 2
[The association of methylenetetrahydrofolate reductase gene polymorphism with nephropathy in type 2 diabetes mellitus in Chinese]
Diabetes Mellitus, Type 2
[The relationship of methylenetetrahydrofolate reductase gene polymorphism and plasma homocysteine levels in type 2 diabetes mellitus patients with diabetic retinopathy]
Diabetes, Gestational
Associations Between Gestational Diabetes Mellitus Risk and Folate Status in Early Pregnancy and MTHFR C677T Polymorphisms in Chinese Women.
Diabetes, Gestational
Evaluation of Gestational Diabetes Mellitus Risk in South Indian Women Based on MTHFR (C677T) and FVL (G1691A) Mutations.
Diabetes, Gestational
No Association Between ADIPOQ or MTHFR Polymorphisms and Gestational Diabetes Mellitus in South African Women.
Diabetes, Gestational
Risk factors of cerebral ischemia in infants born to mothers with gestational diabetes.
Diabetic Angiopathies
Genetic polymorphism of methylenetetrahydrofolate reductase as a risk factor for diabetic nephropathy in Chinese type 2 diabetic patients.
Diabetic Angiopathies
MTHFR gene variant is not associated with diabetic nephropathy in Japanese.
Diabetic Angiopathies
The relationship between MTHFR gene polymorphisms, plasma homocysteine levels and diabetic retinopathy in type 2 diabetes mellitus.
Diabetic Angiopathies
Total plasma homocysteine is associated with hypertension in Type I diabetic patients.
Diabetic Angiopathies
[The relationship between the mutation of methylenetetrahydrofolate reductase gene 677C-->T and the diabetic microangiopathy]
Diabetic Nephropathies
A common mutation of the methylenetetrahydrofolate reductase gene as a risk factor for diabetic nephropathy.
Diabetic Nephropathies
A study on the correlation between MTHFR promoter methylation and diabetic nephropathy.
Diabetic Nephropathies
An updated meta-analysis of methylenetetrahydrofolate reductase gene 677C/T polymorphism with diabetic nephropathy and diabetic retinopathy.
Diabetic Nephropathies
Association between end-stage diabetic nephropathy and MTHFR (C677T and A1298C) gene polymorphisms.
Diabetic Nephropathies
Association Between MTHFR C677T Polymorphism and Diabetic Nephropathy in Chinese Population: Appraisal of a Recent Meta-analysis.
Diabetic Nephropathies
Association between MTHFR C677T polymorphism and diabetic nephropathy in the Chinese population: An updated meta-analysis and review.
Diabetic Nephropathies
Association between MTHFR C677T polymorphism and diabetic nephropathy or diabetes mellitus risk: need for clarification of data in a recent meta-analysis.
Diabetic Nephropathies
Association of methylenetetrahydrofolate reductase gene polymorphism and diabetic nephropathy in type 2 diabetes?
Diabetic Nephropathies
Blood S-adenosylmethionine concentrations and lymphocyte methylenetetrahydrofolate reductase activity in diabetes mellitus and diabetic nephropathy.
Diabetic Nephropathies
Differential contribution of MTHFR C677T variant to the risk of diabetic nephropathy in Lebanese and Bahraini Arabs.
Diabetic Nephropathies
Effect of MTHFR C677T genotype on survival in type 2 diabetes patients with end-stage diabetic nephropathy.
Diabetic Nephropathies
Effects of the C677T and A1298C polymorphisms of the MTHFR gene on the genetic predisposition for diabetic nephropathy.
Diabetic Nephropathies
Genetic polymorphism of methylenetetrahydrofolate reductase as a risk factor for diabetic nephropathy in Chinese type 2 diabetic patients.
Diabetic Nephropathies
Genetic Predisposition for Development of Nephropathy in Type 2 Diabetes Mellitus.
Diabetic Nephropathies
Interaction of eNOS polymorphism with MTHFR variants increase the risk of diabetic nephropathy and its progression in type 2 diabetes mellitus patients.
Diabetic Nephropathies
Interaction of MTHFR 1298C with ACE D Allele Augments the Risk of Diabetic Nephropathy in Western Iran.
Diabetic Nephropathies
Interaction of MTHFR C677T polymorphism with smoking in susceptibility to diabetic nephropathy in Chinese men with type 2 diabetes.
Diabetic Nephropathies
Is the C677T Polymorphism in Methylenetetrahydrofolate Reductase Gene a Risk Factor for Diabetic Nephropathy or Diabetes Mellitus in a Chinese Population?
Diabetic Nephropathies
Methylenetetrahydrofolate reductase (MTHFR) C677T gene polymorphism and diabetic nephropathy susceptibility in patients with type 2 diabetes mellitus.
Diabetic Nephropathies
Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and susceptibility to diabetic nephropathy in Chinese type 2 diabetic patients: a meta-analysis.
Diabetic Nephropathies
METHYLENETETRAHYDROFOLATE REDUCTASE C677T POLYMORPHISM IN PATIENTS WITH HENOCH-SCHÖNLEIN PURPURA.
Diabetic Nephropathies
Methylenetetrahydrofolate reductase gene polymorphism and susceptibility to diabetic nephropathy in type 1 diabetes.
Diabetic Nephropathies
Methylenetetrahydrofolate reductase gene polymorphism as a risk factor for diabetic nephropathy in IDDM patients.
Diabetic Nephropathies
Methylenetetrahydrofolate reductase gene polymorphism as a risk factor for diabetic nephropathy in NIDDM patients.
Diabetic Nephropathies
Methylenetetrahydrofolate reductase gene polymorphism as a risk factor for diabetic nephropathy: a meta-analysis.
Diabetic Nephropathies
Methylenetetrahydrofolate reductase gene polymorphism is not related to diabetic nephropathy in Japanese Type 2 diabetic patients.
Diabetic Nephropathies
Methylenetetrahydrofolate reductase genetic polymorphism and the risk of diabetic nephropathy in type 2 diabetic patients.
Diabetic Nephropathies
Methyltetrahydrofolate reductase C677T gene mutation and hyperhomocysteinemia as a novel risk factor for diabetic nephropathy.
Diabetic Nephropathies
MTHFR 677T variant contributes to diabetic nephropathy risk in Caucasian individuals with type 2 diabetes: A meta-analysis.
Diabetic Nephropathies
MTHFR C677T and A1298C gene polymorphisms and hyperhomocysteinemia as risk factors of diabetic nephropathy in type 2 diabetes patients.
Diabetic Nephropathies
MTHFR C677T, A1298C and ACE I/D polymorphisms as risk factors for diabetic nephropathy among type 2 diabetic patients.
Diabetic Nephropathies
MTHFR gene C677T polymorphism and type 2 diabetic nephropathy in Asian populations: a meta-analysis.
Diabetic Nephropathies
MTHFR gene polymorphism and diabetic nephropathy in type 1 diabetes.
Diabetic Nephropathies
MTHFR gene polymorphism as an exacerbation factor of diabetic nephropathy in type 2 diabetes. Analysis in Japanese male hemodialysis patients.
Diabetic Nephropathies
MTHFR gene polymorphism is susceptible to diabetic retinopathy but not to diabetic nephropathy in Japanese type 2 diabetic patients.
Diabetic Nephropathies
MTHFR gene variant is not associated with diabetic nephropathy in Japanese.
Diabetic Nephropathies
No association between MTHFR gene polymorphism and diabetic nephropathy in Japanese type II diabetic patients with proliferative diabetic retinopathy.
Diabetic Nephropathies
Relationship between methylenetetrahydrofolate reductase (MTHFR) A1298C gene polymorphism and type 2 diabetic nephropathy risk: a meta-analysis.
Diabetic Nephropathies
Reply: Is the C677T Polymorphism in Methylenetetrahydrofolate Reductase Gene a Risk Factor for Diabetic Nephropathy or Diabetes Mellitus in a Chinese Population?
Diabetic Nephropathies
Synergistic effects of the MTHFR C677T and A1298C polymorphisms on the increased risk of micro- and macro-albuminuria and progression of diabetic nephropathy among Iranians with type 2 diabetes mellitus.
Diabetic Nephropathies
The association between end-stage diabetic nephropathy and methylenetetrahydrofolate reductase genotype with macroangiopathy in type 2 diabetes mellitus.
Diabetic Nephropathies
The association between two common mutations C677T and A1298C in human methylenetetrahydrofolate reductase gene and the risk for diabetic nephropathy in type II diabetic patients.
Diabetic Nephropathies
The C677T methylenetetrahydrofolate reductase gene mutation and nephropathy in type 2 diabetes mellitus.
Diabetic Nephropathies
The MTHFR promoter hypermethylation pattern associated with the A1298C polymorphism influences lipid parameters and glycemic control in diabetic patients.
Diabetic Nephropathies
The relationship between methylenetetrahydrofolate reductase C677T gene polymorphism and diabetic nephropathy in Croatian type 2 diabetic patients.
Diabetic Nephropathies
The relationship of the methylenetetrahydrofolate reductase C677T gene polymorphism in Turkish type 2 diabetic patients with and without nephropathy.
Diabetic Nephropathies
[Relationship between methylenetetrahydrofolate reductase gene polymorphism and diabetic nephropathy]
Diabetic Nephropathies
[The association of methylenetetrahydrofolate reductase gene polymorphism with nephropathy in type 2 diabetes mellitus in Chinese]
Diabetic Neuropathies
Association of MTHFR gene C677T mutation with diabetic peripheral neuropathy and diabetic retinopathy.
Diabetic Neuropathies
Diabetic neuropathy is not associated with homocysteine, folate, vitamin B12 levels, and MTHFR C677T mutation in type 2 diabetic outpatients taking metformin.
Diabetic Neuropathies
The MTHFR C677T polymorphism influences the efficacy of folic acid supplementation on the nerve conduction studies in patients with diabetic polyneuropathy; A randomized, double blind, placebo-controlled study.
Diabetic Retinopathy
A Meta-Analysis of Association between Methylenetetrahydrofolate Reductase Gene (MTHFR) 677C/T Polymorphism and Diabetic Retinopathy.
Diabetic Retinopathy
An updated meta-analysis of methylenetetrahydrofolate reductase gene 677C/T polymorphism with diabetic nephropathy and diabetic retinopathy.
Diabetic Retinopathy
Association of MTHFR gene C677T mutation with diabetic peripheral neuropathy and diabetic retinopathy.
Diabetic Retinopathy
Diabetic retinopathy in Euro-Brazilian type 2 diabetic patients: relationship with polymorphisms in the aldose reductase, the plasminogen activator inhibitor-1 and the methylenetetrahydrofolate reductase genes.
Diabetic Retinopathy
Effect of polymorphisms of the MTHFR and APOE genes on susceptibility to diabetes and severity of diabetic retinopathy in Brazilian patients.
Diabetic Retinopathy
Effects of Ocufolin on retinal microvasculature in patients with mild non-proliferative diabetic retinopathy carrying polymorphisms of the MTHFR gene.
Diabetic Retinopathy
Genetic variants in ICAM1, PPARGC1A and MTHFR are potentially associated with different phenotypes of diabetic retinopathy.
Diabetic Retinopathy
Improved conjunctival microcirculation in diabetic retinopathy patients with MTHFR polymorphisms after Ocufolin Administration.
Diabetic Retinopathy
Methylenetetrahydrofolate reductase C677T polymorphism and diabetic retinopathy risk: a meta-analysis of the Chinese population.
Diabetic Retinopathy
Methylenetetrahydrofolate reductase C677T polymorphism and diabetic retinopathy.
Diabetic Retinopathy
Methylenetrahydrofolate Reductase Gene C677T Polymorphism and Diabetic Retinopathy: a Meta-Analysis.
Diabetic Retinopathy
MTHFR gene polymorphism as a risk factor for diabetic retinopathy in type 2 diabetic patients without serum creatinine elevation.
Diabetic Retinopathy
MTHFR gene polymorphism is susceptible to diabetic retinopathy but not to diabetic nephropathy in Japanese type 2 diabetic patients.
Diabetic Retinopathy
No association between MTHFR gene polymorphism and diabetic nephropathy in Japanese type II diabetic patients with proliferative diabetic retinopathy.
Diabetic Retinopathy
No association between the MTHFR gene polymorphism and diabetic retinopathy in type 2 diabetic patients without overt nephropathy.
Diabetic Retinopathy
The MTHFR promoter hypermethylation pattern associated with the A1298C polymorphism influences lipid parameters and glycemic control in diabetic patients.
Diabetic Retinopathy
The relationship between methylenetetrahydrofolate reductase C677T polymorphism and diabetic retinopathy: A meta-analysis in multiethnic groups.
Diabetic Retinopathy
The relationship between MTHFR gene polymorphisms, plasma homocysteine levels and diabetic retinopathy in type 2 diabetes mellitus.
Diabetic Retinopathy
[The relationship of methylenetetrahydrofolate reductase gene polymorphism and plasma homocysteine levels in type 2 diabetes mellitus patients with diabetic retinopathy]
DiGeorge Syndrome
A Bibliometric Analysis of Cleft Lip and Palate-Related Publication Trends From 2000 to 2017.
Diverticulitis
Role of acquired and hereditary thrombotic risk factors in colon ischemia of ambulatory patients.
Down Syndrome
Abnormal folate metabolism and genetic polymorphism of the folate pathway in a child with Down syndrome and neural tube defect.
Down Syndrome
Abnormal folate metabolism and mutation in the methylenetetrahydrofolate reductase gene may be maternal risk factors for Down syndrome.
Down Syndrome
Abnormal folate metabolism in mothers with Down syndrome offspring: Review of the literature.
Down Syndrome
Abnormal folic acid-homocysteine metabolism as maternal risk factors for Down syndrome in Japan.
Down Syndrome
Absence of association of fetal MTHFR C677T polymorphism with prenatal Down syndrome pregnancies.
Down Syndrome
Analysis of seven maternal polymorphisms of genes involved in homocysteine/folate metabolism and risk of Down syndrome offspring.
Down Syndrome
Association of methylenetetrahydrofolate reductase gene 677C > T polymorphism and Down syndrome.
Down Syndrome
Combined folate gene MTHFD and TC polymorphisms as maternal risk factors for Down syndrome in China.
Down Syndrome
Evaluation of C677T and A1298C polymorphisms of the MTHFR gene as maternal risk factors for Down syndrome and congenital heart defects.
Down Syndrome
Fission Yeast Methylenetetrahydrofolate Reductase Ensures Mitotic and Meiotic Chromosome Segregation Fidelity.
Down Syndrome
Folate metabolism gene polymorphisms MTHFR C677T and A1298C and risk for Down syndrome offspring: a meta-analysis.
Down Syndrome
Functional inference of methylenetetrahydrofolate reductase gene polymorphisms on enzyme stability as a potential risk factor for Down syndrome in Croatia.
Down Syndrome
Genetic polymorphisms involved in folate metabolism and elevated plasma concentrations of homocysteine: maternal risk factors for Down syndrome in Brazil.
Down Syndrome
Increased MTHFR promoter methylation in mothers of Down syndrome individuals.
Down Syndrome
Investigating the impact of the Down syndrome related common MTHFR 677C>T polymorphism in the Danish population.
Down Syndrome
Maternal methylenetetrahydrofolate reductase C677T polymorphism and down syndrome risk: a meta-analysis from 34 studies.
Down Syndrome
Maternal MTHFR polymorphism (677 C-T) and risk of Down's syndrome child: meta-analysis.
Down Syndrome
Maternal polymorphisms 677C-T and 1298A-C of MTHFR, and 66A-G MTRR genes: Is there any relationship between polymorphisms of the folate pathway, maternal homocysteine levels, and the risk for having a child with Down syndrome?
Down Syndrome
Maternal polymorphisms for methyltetrahydrofolate reductase and methionine synthetase reductase and risk of children with Down syndrome.
Down Syndrome
Meta-analysis of Methylenetetrahydrofolate reductase maternal gene in Down syndrome: increased susceptibility in women carriers of the MTHFR 677T allele.
Down Syndrome
Methionine synthase (MTR) 2756 (A --> G) polymorphism, double heterozygosity methionine synthase 2756 AG/methionine synthase reductase (MTRR) 66 AG, and elevated homocysteinemia are three risk factors for having a child with Down syndrome.
Down Syndrome
Methylenetetrahydrofolate Reductase Dimer Configuration as a Risk Factor for Maternal Meiosis I-Derived Trisomy 21.
Down Syndrome
Methylenetetrahydrofolate reductase enzyme polymorphisms as maternal risk for Down syndrome among Turkish women.
Down Syndrome
Methylenetetrahydrofolate reductase gene polymorphisms and their association with trisomy 21.
Down Syndrome
Methylenetetrahydrofolate reductase polymorphism in the etiology of Down syndrome.
Down Syndrome
Methylenetetrahydrofolate reductase polymorphism is not risk factor for Down syndrome in North India.
Down Syndrome
Methylenetetrahydrofolate reductase polymorphisms C677T and A1298C as maternal risk factors for Down syndrome in Jordan.
Down Syndrome
MTHFR 677 TT genotype in a mother and her child with Down syndrome, atrioventricular canal and exstrophy of the bladder: implications of a mutual genetic risk factor?
Down Syndrome
MTHFR 677C-->T and 1298A-->C polymorphisms in children with Down syndrome and acute myeloid leukemia in Brazil.
Down Syndrome
MTHFR 677C-T polymorphism is not excluded as maternal risk for Down syndrome among Turkish women.
Down Syndrome
MTHFR C677T and A1298C polymorphisms are risk factors for Down's syndrome in Indian mothers.
Down Syndrome
MTHFR C677T and A1298C polymorphisms as a risk factor for congenital heart defects in Down syndrome.
Down Syndrome
MTHFR Gene variants C677T, A1298C and association with Down syndrome: A Case-control study from South India.
Down Syndrome
MTHFR genetic polymorphism as a risk factor in Egyptian mothers with Down syndrome children.
Down Syndrome
MTHFR promoter hypermethylation may lead to congenital heart defects in Down syndrome.
Down Syndrome
No association between common polymorphisms in genes of folate and homocysteine metabolism and the risk of Down's syndrome among French mothers.
Down Syndrome
Polymorphisms in folate and homocysteine metabolizing genes and chromosome damage in mothers of Down syndrome children.
Down Syndrome
Polymorphisms in genes involved in folate metabolism as maternal risk factors for Down syndrome in China.
Down Syndrome
Polymorphisms in genes involved in folate metabolism as maternal risk factors for Down syndrome.
Down Syndrome
Polymorphisms of the MTHFR gene in mothers of children with trisomy 21 (Down syndrome) in a Polish population.
Down Syndrome
Preferential transmission of the MTHFR 677 T allele to infants with Down syndrome: implications for a survival advantage.
Down Syndrome
Prevalence of methylenetetrahydrofolate reductase 677 C-T polymorphism among mothers of Down syndrome children.
Down Syndrome
Prevalence of MTHFR C677T polymorphism in north Indian mothers having babies with Trisomy 21 Down syndrome.
Down Syndrome
Relationship between polymorphisms in genes involved in homocysteine metabolism and maternal risk for Down syndrome in Brazil.
Down Syndrome
Risk of Down syndrome conferred by MTHFR C677T polymorphism: Ethnic variations.
Down Syndrome
Role of folate-homocysteine pathway gene polymorphisms and nutritional cofactors in Down syndrome: A triad study.
Down Syndrome
Screening of six polymorphisms related with folate metabolism in parents of individuals with Down syndrome.
Down Syndrome
The association between maternal methylenetetrahydrofolate reductase C677T and A1298C polymorphism and birth defects and adverse pregnancy outcomes.
Down Syndrome
The biochemical structure and function of methylenetetrahydrofolate reductase provide the rationale to interpret the epidemiological results on the risk for infants with Down syndrome.
Down Syndrome
The genetics of folate metabolism and maternal risk of birth of a child with Down syndrome and associated congenital heart defects.
Down Syndrome
The impact of folate pathway polymorphisms combined to nutritional deficiency as a maternal predisposition factor for Down syndrome.
Down Syndrome
Vitamin D3 increases the Caspase-3 p12, MTHFR, and P-glycoprotein reducing amyloid-?42 in the kidney of a mouse model for Down syndrome.
Down Syndrome
[Association of MTHFR and MTRR genes polymorphisms with non-disjunctions of chromosomes 18 and 21].
Down Syndrome
[Folate gene polymorphism and the risk of Down syndrome pregnancies in young Chinese women]
Down Syndrome
[Rapid screening for MTHFR gene 677C>T polymorphism in Down syndrome using high resolution melting curve and pyrosequencing.]
Down Syndrome
[The relationship between polymorphism of gene involved in folate metabolism, homocysteine level and risk of Down syndrome.]
Drug-Related Side Effects and Adverse Reactions
Pharmacogenetic association with adverse drug reactions to azathioprine immunosuppressive therapy following liver transplantation.
Drug-Related Side Effects and Adverse Reactions
SLCO1B1 Polymorphisms are Associated With Drug Intolerance in Childhood Leukemia Maintenance Therapy.
Drug-Related Side Effects and Adverse Reactions
Variants in the dihydropyrimidine dehydrogenase, methylenetetrahydrofolate reductase and thymidylate synthase genes predict early toxicity of 5-fluorouracil in colorectal cancer patients.
Drug-Related Side Effects and Adverse Reactions
[Pharmacogenomics of methrotexate: a strategy for a customized therapeutic scheme for patients with rheumatoid arthritis]
Dry Eye Syndromes
Angiotensin converting enzyme and methylenetetrahydrofolate reductase gene variations in fibromyalgia syndrome.
Ductus Arteriosus, Patent
Correlation Between Methyltetrahydrofolate Reductase (MTHFR) Polymorphisms and Isolated Patent Ductus Arteriosus in Taiwan.
Ductus Arteriosus, Patent
Genomics and Epigenomics of Congenital Heart Defects: Expert Review and Lessons Learned in Africa.
Ductus Arteriosus, Patent
Maternal and offspring MTHFR gene C677T polymorphism as predictors of congenital atrial septal defect and patent ductus arteriosus.
Dyskinesias
5,10-methylenetetrahydrofolate reductase C677T gene polymorphism can influence age at onset of Parkinson's disease.
Dyslipidemias
Association between ACE (rs4646994), FABP2 (rs1799883), MTHFR (rs1801133), FTO (rs9939609) Genes Polymorphism and Type 2 Diabetes with Dyslipidemia.
Dyslipidemias
Association Between Homocysteine Level and Methylenetetrahydrofolate Reductase Gene Polymorphisms in Type 2 Diabetes Accompanied by Dyslipidemia.
Dyslipidemias
Diabetic neuropathy is not associated with homocysteine, folate, vitamin B12 levels, and MTHFR C677T mutation in type 2 diabetic outpatients taking metformin.
Dyslipidemias
Impact of KCNJ11 rs5219, UCP2 rs659366, and MTHFR rs1801133 Polymorphisms on Type 2 Diabetes: A Cross-Sectional Study.
Dyslipidemias
Individual and Joint Associations of Methylenetetrahydrofolate Reductase C677T Genotype and Plasma Homocysteine With Dyslipidemia in a Chinese Population With Hypertension.
Dyslipidemias
Is there additional effect of MTHFR C677T mutation on lipid abnormalities in renal allograft recipients?
Dyslipidemias
Joint associations of folate, homocysteine and MTHFR, MTR and MTRR gene polymorphisms with dyslipidemia in a Chinese hypertensive population: a cross-sectional study.
Dyslipidemias
Methylenetetrahydrofolate reductase C677T gene polymorphism and the association with dyslipidemia in type 2 diabetic Palestinian patients.
Dyslipidemias
Modeling premature occurrence of acute coronary syndrome with atherogenic and thrombogenic risk factors and gene markers in extended families.
Dyslipidemias
Possible roles of methylenetetrahydrofolate reductase polymorphism and folate status in patients with early hepatitis C virus genotype 4.
Dyslipidemias
Supplementation with Watermelon Extract Reduces Total Cholesterol and LDL Cholesterol in Adults with Dyslipidemia under the Influence of the MTHFR C677T Polymorphism.
Dyspnea
High Circulating Folate and Vitamin B-12 Concentrations in Women During Pregnancy Are Associated with Increased Prevalence of Atopic Dermatitis in Their Offspring.
Eclampsia
High frequency of methylenetetrahydrofolate reductase 677TT genotype in Hungarian HELLP syndrome patients determined by quantitative real-time PCR.
Eclampsia
Methylenetetrahydrofolate reductase 677 C --> T polymorphism, plasma folate, vitamin B(12) concentrations, and risk of preeclampsia among black African women from Zimbabwe.
Eclampsia
[Folic acid levels, homocysteine and polymorphism of methylenetetrahydrofolate reductase enzyme (MTHFR) in patients with pre-eclampsia and eclampsia]
Eczema
Neonatal folate, homocysteine, vitamin B12 levels and methylenetetrahydrofolate reductase variants in childhood asthma and eczema.
Ehlers-Danlos Syndrome
[Investigation of detoxification polymorphisms genes, methylenetetrahydrofolate-reductase (MTHFR) and P53 in the radiosensitive human cells]
Embolic Stroke
Association of MTHFR C677T Genotype With Ischemic Stroke Is Confined to Cerebral Small Vessel Disease Subtype.
Embolic Stroke
MTHFR Gene Polymorphisms Prevalence and Cardiovascular Risk Factors Involved in Cardioembolic Stroke Type and Severity.
Embolism
Acute renal infarction associated with homozygous methylenetetrahydrofolate reductase mutation C677T and IgA beta-2-glycoprotein antibodies.
Embolism
Tricuspid valve thrombus and pulmonary embolus in an infant with homozygous thermolabile methylenetetrahydrofolate reductase and heterozygous prothrombin G20210A variant.
Embryo Loss
Genotypes of the C677T and A1298C polymorphisms of the MTHFR gene as a cause of human spontaneous embryo loss.
Embryo Loss
Increased frequency of combined methylenetetrahydrofolate reductase C677T and A1298C mutated alleles in spontaneously aborted embryos.
Encephalocele
Amniotic fluid homocysteine levels, 5,10-methylenetetrahydrafolate reductase genotypes, and neural tube closure sites.
Encephalocele
C677T mutation in the MTHFR gene was not found in patients with frontoethmoidal encephalocele in East Java, Indonesia.
Encephalocele
Evidence of gene-gene interactions between MTHFD1 and MTHFR in relation to anterior encephalocele susceptibility in Northeast India.
Encephalomalacia
Diffuse multicystic encephalomalacia in a preterm baby due to homozygous methylenetetrahydrofolate reductase 677 C-->T mutation.
End Stage Liver Disease
MTHFR C677T polymorphism and risk of HCC in patients with liver cirrhosis: role of male gender and alcohol consumption.
Endometrial Neoplasms
Dietary folate intake, MTHFR genetic polymorphisms, and the risk of endometrial cancer among Chinese women.
Endometrial Neoplasms
Effects of methylenetetrahydrofolate reductase single-nucleotide polymorphisms on breast, cervical, ovarian, and endometrial cancer susceptibilities.
Endometrial Neoplasms
Endometrial carcinoma in tamoxifen-treated breast cancer patient: clinicopathological, immunohistochemical, and genetic analysis.
Endometrial Neoplasms
Germ line polymorphisms in cytochrome-P450 1A1 (C4887 CYP1A1) and methylenetetrahydrofolate reductase (MTHFR) genes and endometrial cancer susceptibility.
Endometrial Neoplasms
Methylenetetrahydrofolate reductase gene polymorphism in endometrial cancer: A systematic review and meta-analysis.
Endometrial Neoplasms
No association between MTHFR 677 C->T or 1298 A->C polymorphisms and endometrial cancer risk.
Endometriosis
Polymorphic variants of folate and choline metabolism genes and the risk of endometriosis-associated infertility.
Eosinophilia
MTHFR C677T polymorphism and anatomopathological characteristics with prognostic significance in sporadic colorectal cancer.
Eosinophilia
Transient severe eosinophilia precipitating massive venous thrombosis in a patient with hereditary thrombophilia.
Epilepsy
A common mutation in the methylenetetrahydrofolate reductase gene is a determinant of hyperhomocysteinemia in epileptic patients receiving anticonvulsants.
Epilepsy
A high frequency of the MTHFR 677C>T polymorphism in Scottish women with epilepsy: possible role in pathogenesis.
Epilepsy
Antiepileptic drugs, hyperhomocysteinemia and B-vitamins supplementation in patients with epilepsy.
Epilepsy
Are the methylenetetrahydrofolate reductase 1298 and 677 gene polymorphisms related to optic glioma and hamartoma risk in neurofibromatosis type 1 patients?
Epilepsy
Association between methylenetetrahydrofolate reductase C677T polymorphism and epilepsy susceptibility: A meta-analysis.
Epilepsy
Association of the C677T and A1298C polymorphisms in the 5,10 methylenetetrahydrofolate reductase gene in patients with migraine risk.
Epilepsy
Association of the C677T polymorphism in the MTHFR gene with migraine: a meta-analysis.
Epilepsy
Associations between genetic variation in one-carbon metabolism and leukocyte DNA methylation in valproate-treated patients with epilepsy.
Epilepsy
Effects of antiepileptic drug monotherapy on one-carbon metabolism and DNA methylation in patients with epilepsy.
Epilepsy
Effects of MTHFR and ABCC2 gene polymorphisms on antiepileptic drug responsiveness in Jordanian epileptic patients.
Epilepsy
Effects of MTHFR gene polymorphism on the clinical and electrophysiological characteristics of migraine.
Epilepsy
Frequency of the C677T variant of the methylenetetrahydrofolate reductase (MTHFR) gene in patients with migraine with or without aura - a preliminary report.
Epilepsy
Genetic Polymorphisms in Enzymes Involved in One-Carbon Metabolism and Anti-epileptic Drug Monotherapy on Homocysteine Metabolism in Patients With Epilepsy.
Epilepsy
Haplotype analysis of the folate-related genes MTHFR, MTRR, and MTR and migraine with aura.
Epilepsy
Influence of MTHFR genotype on contingent negative variation and MRI abnormalities in migraine.
Epilepsy
Influence of the MTHFR genotype on the rate of malformations following exposure to antiepileptic drugs in utero.
Epilepsy
Interictal epileptiform discharges on electroencephalography in children with methylenetetrahydrofolate reductase (MTHFR) polymorphisms.
Epilepsy
Interrelationships among the MTHFR 677C>T polymorphism, migraine, and cardiovascular disease.
Epilepsy
Lack of association between the MTHFR C677T variant and migraine with aura in an older population: Could selective survival play a role?
Epilepsy
Methylenetetrahydrofolate reductase C677T polymorphism and susceptibility to epilepsy.
Epilepsy
Migraine and coronary artery disease: an open study on the genetic polymorphism of the 5, 10 methylenetetrahydrofolate (MTHFR) and angiotensin I-converting enzyme (ACE) genes.
Epilepsy
Migraine mediates the influence of C677T MTHFR genotypes on ischemic stroke risk with a stroke-subtype effect.
Epilepsy
MTHFR 677C>T and ACE D/I Polymorphisms in Migraine: A Systematic Review and Meta-Analysis.
Epilepsy
MTHFR C677T Genotype as a Risk factor for Epilepsy Including Post-Traumatic Epilepsy in a Representative Military Cohort.
Epilepsy
Pregnancy outcomes in women with epilepsy and MTHFR mutations supplemented with methylated folate and methylcobalamin (methylated B12).
Epilepsy
Role of folic acid depletion on homocysteine serum level in children and adolescents with epilepsy and different MTHFR C677T genotypes.
Epilepsy
Role of plasma homocysteine levels and MTHFR polymorphisms on IQ scores in children and young adults with epilepsy treated with antiepileptic drugs.
Epilepsy
Screening for C677T and A1298C MTHFR polymorphisms in patients with epilepsy and risk of hyperhomocysteinemia.
Epilepsy
Testing of variants of the MTHFR and ESR1 genes in 1798 Finnish individuals fails to confirm the association with migraine with aura.
Epilepsy
The 677C --> T mutation in the methylenetetrahydrofolate reductase (MTHFR) gene in epileptic patients affected by systemic lupus erythematosus.
Epilepsy
The methylenetetrahydrofolate reductase gene variant C677T influences susceptibility to migraine with aura.
Epilepsy
Thymidylate synthase promoter tandem repeat and MTHFD1 R653Q polymorphisms modulate the risk for migraine conferred by the MTHFR T677 allele.
Epilepsy
[Mutation of MTHFR gene as marker of endothelial dysfunction in patients diagnosed of migraine with aura.]
Epilepsy, Generalized
MTHFR homozygous mutation and additional risk factors for cerebral infarction in a large Italian family.
Epilepsy, Post-Traumatic
MTHFR C677T Genotype as a Risk factor for Epilepsy Including Post-Traumatic Epilepsy in a Representative Military Cohort.
Epilepsy, Tonic-Clonic
Effects of MTHFR and ABCC2 gene polymorphisms on antiepileptic drug responsiveness in Jordanian epileptic patients.
Epileptic Syndromes
Adolescence/adult onset MTHFR deficiency may manifest as isolated and treatable distinct neuro-psychiatric syndromes.
Equinus Deformity
Whole genome sequencing identifies ANXA3 and MTHFR mutations in a large family with an unknown equinus deformity associated genetic disorder.
Erectile Dysfunction
Role of Methylenetetrahydrofolate Reductase Gene Polymorphisms (C677T, A1298C, and G1793A) in the Development of Early Onset Vasculogenic Erectile Dysfunction.
Erectile Dysfunction
The relationship between the C677T polymorphism of the MTHFR gene and serum levels of luteinizing hormone in males with erectile dysfunction.
Erectile Dysfunction
Treatment of Erectile Dysfunction Due to C677T Mutation of the MTHFR Gene with Vitamin B6 and Folic acid in Patients Non Responders to PDE5i.
Esophageal Neoplasms
DNA Repair Gene and MTHFR Gene Polymorphisms as Prognostic Markers in Locally Advanced Adenocarcinoma of the Esophagus or Stomach Treated with Cisplatin and 5-Fluorouracil-Based Neoadjuvant Chemotherapy.
Esophageal Neoplasms
Folate intake, methylenetetrahydrofolate reductase polymorphisms in association with the prognosis of esophageal squamous cell carcinoma.
Esophageal Neoplasms
Folate intake, methylenetetrahydrofolate reductase polymorphisms, and risk of esophageal cancer.
Esophageal Neoplasms
Gene-environment interactions between alcohol drinking and the MTHFR C677T polymorphism impact on esophageal cancer risk: results of a case-control study in Japan.
Esophageal Neoplasms
Genetic polymorphism of MTHFR A1298C and esophageal cancer susceptibility: a meta-analysis.
Esophageal Neoplasms
Hyperhomocysteinemia, methylenetetrahydrofolate reductase c.677C>T polymorphism, and risk of cancer: cross-sectional and prospective studies and meta-analyses of 75,000 cases and 93,000 controls.
Esophageal Neoplasms
Interaction of methylenetetrahydrofolate reductase C677T, cytochrome P4502E1 polymorphism and environment factors in esophageal cancer in Kazakh population.
Esophageal Neoplasms
LncRNA HOTAIR-mediated MTHFR methylation inhibits 5-fluorouracil sensitivity in esophageal cancer cells.
Esophageal Neoplasms
Meta-analysis of the Relationship between the Metholenetetrahydrofolate Reductase C677T Genetic Polymorphism, Folate Intake and Esophageal Cancer.
Esophageal Neoplasms
Methylene tetrahydrofolate reductasel reductase C677T polymorphisms and esophageal cancer susceptibility: A meta-analysis based on Chinese Han population.
Esophageal Neoplasms
Methylenetetrahydrofolate Reductase Genetic Polymorphisms and Esophageal Squamous Cell Carcinoma Susceptibility: A Meta-analysis of Case-control Studies.
Esophageal Neoplasms
Methylenetetrahydrofolate reductase genetic polymorphisms and esophageal squamous cell carcinoma susceptibility: A meta-analysis of case-control studies.
Esophageal Neoplasms
Methylenetetrahydrofolate Reductase Polymorphisms and Susceptibility to Esophageal Cancer in Chinese Populations: a Meta-analysis.
Esophageal Neoplasms
Relationship between MTHFR Gene Polymorphisms and Gastrointestinal Tumors Development: Perspective from Eastern Part of Turkey.
Esophageal Neoplasms
Relationship between the Methylation of Folic Acid Metabolism-Related Genes and the Incidence and Prognosis of Esophageal Cancer among Ethnic Kazakhs.
Esophageal Neoplasms
Review and pooled analysis of studies on MTHFR C677T polymorphism and esophageal cancer.
Esophageal Neoplasms
Susceptibility to gastric cardia adenocarcinoma and genetic polymorphisms in methylenetetrahydrofolate reductase in an at-risk Chinese population.
Esophageal Neoplasms
The Methylenetetrahydrofolate Reductase C677T Polymorphism Influences Risk of Esophageal Cancer in Chinese.
Esophageal Neoplasms
[A case-control study on the polymorphisms of methylenetetrahydrofolate reductase 1298A-->C and susceptibility of esophageal cancer]
Esophageal Neoplasms
[Study on the ingestion of folate and polymorphism of MTHFR C677T with esophageal cancer in Xinjiang Kazakh]
Esophageal Squamous Cell Carcinoma
Aberrant DNA methylation of P16, MGMT, and hMLH1 genes in combination with MTHFR C677T genetic polymorphism and folate intake in esophageal squamous cell carcinoma.
Esophageal Squamous Cell Carcinoma
Aberrant DNA methylation of P16, MGMT, and hMLH1 genes in combination with MTHFR C677T genetic polymorphism in esophageal squamous cell carcinoma.
Esophageal Squamous Cell Carcinoma
Association between a microRNA-214 binding site polymorphism in the methylenetetrahydrofolate reductase gene and esophageal squamous cell carcinoma.
Esophageal Squamous Cell Carcinoma
Diet folate, DNA methylation and genetic polymorphisms of MTHFR C677T in association with the prognosis of esophageal squamous cell carcinoma.
Esophageal Squamous Cell Carcinoma
Folate intake, methylenetetrahydrofolate reductase polymorphisms in association with the prognosis of esophageal squamous cell carcinoma.
Esophageal Squamous Cell Carcinoma
Folate intake, MTHFR polymorphisms, and risk of esophageal, gastric, and pancreatic cancer: a meta-analysis.
Esophageal Squamous Cell Carcinoma
Genetic polymorphisms and susceptibility to esophageal cancer among Chinese population (review).
Esophageal Squamous Cell Carcinoma
Genetic polymorphisms in folate- metabolizing enzymes and risk of gastroesophageal cancers: a potential nutrient-gene interaction in cancer development.
Esophageal Squamous Cell Carcinoma
Genetic Variants in MTHFR Gene Predict ? 2 Radiation Pneumonitis in Esophageal Squamous Cell Carcinoma Patients Treated with Thoracic Radiotherapy.
Esophageal Squamous Cell Carcinoma
Genetic variations in MTHFR and esophageal squamous cell carcinoma susceptibility in Chinese Han population.
Esophageal Squamous Cell Carcinoma
Head and neck cancer susceptibility: a genetic marker in the methylenetetrahydrofolate reductase gene.
Esophageal Squamous Cell Carcinoma
Methylenetetrahydrofolate reductase C677T polymorphism and predisposition towards esophageal squamous cell carcinoma in a German Caucasian and a northern Chinese population.
Esophageal Squamous Cell Carcinoma
Methylenetetrahydrofolate Reductase Genetic Polymorphisms and Esophageal Squamous Cell Carcinoma Susceptibility: A Meta-analysis of Case-control Studies.
Esophageal Squamous Cell Carcinoma
Methylenetetrahydrofolate reductase genetic polymorphisms and esophageal squamous cell carcinoma susceptibility: A meta-analysis of case-control studies.
Esophageal Squamous Cell Carcinoma
Methylenetetrahydrofolate reductase polymorphisms increase risk of esophageal squamous cell carcinoma in a Chinese population.
Esophageal Squamous Cell Carcinoma
MTHFR C677T genetic polymorphism in combination with serum vitamin B2, B12 and aberrant DNA methylation of P16 and P53 genes in esophageal squamous cell carcinoma and esophageal precancerous lesions: a case-control study.
Esophageal Squamous Cell Carcinoma
Polymorphisms of MTHFR and susceptibility to oesophageal adenocarcinoma in a Caucasian United Kingdom population.
Esophageal Squamous Cell Carcinoma
Serum folate, MTHFR C677T polymorphism and esophageal squamous cell carcinoma risk.
Esophageal Squamous Cell Carcinoma
Systematic Review on the Relationship between Genetic Polymorphisms of Methylenetetrahydrofolate Reductase and Esophageal Squamous Cell Carcinoma.
Esophageal Squamous Cell Carcinoma
[Correlation of aberrant methylation of MGMT gene to MTHFR C677T genetic polymorphisms in esophageal squamous cell carcinoma]
Esophagitis
Association of methylenetetrahydrofolate reductase C677T-A1298C polymorphisms with risk for esophageal adenocarcinoma, Barrett's esophagus, and reflux esophagitis.
Esophagitis, Peptic
Association of methylenetetrahydrofolate reductase C677T-A1298C polymorphisms with risk for esophageal adenocarcinoma, Barrett's esophagus, and reflux esophagitis.
Essential Hypertension
A 31 year old woman with essential hypertension grade III and branch retinal vein occlusion with homozygous C677T MTHFR hyperhomocysteinemia and high Lp(a) levels.
Essential Hypertension
A case-control study of the association between the MTHFR gene and essential hypertension in Asian Indians.
Essential Hypertension
A common haplotype on methylenetetrahydrofolate reductase gene modifies the effect of angiotensin-converting enzyme inhibitor on blood pressure in essential hypertension patients--a family-based association study.
Essential Hypertension
A common mutation in methylenetetrahydrofolate reductase gene among the Japanese population.
Essential Hypertension
Association between Hcy levels and the CBS844ins68 and MTHFR C677T polymorphisms with essential hypertension.
Essential Hypertension
Association between methylenetetrahydrofolate reductase (MTHFR) C677T/A1298C polymorphisms and essential hypertension: a systematic review and meta-analysis.
Essential Hypertension
Association between the MTHFR C677T gene polymorphism and essential hypertension in South West Cameroon.
Essential Hypertension
Associations of methylenetetrahydrofolate reductase C677T genotype with blood pressure levels in Chinese population with essential hypertension.
Essential Hypertension
Combined Effect of Factor V Leiden, MTHFR, and Angiotensin-Converting Enzyme (Insertion/Deletion) Gene Mutations in Hypertensive Adult Individuals: A Population-Based Study from Sivas and Canakkale, Turkey.
Essential Hypertension
Effect of enalapril on plasma homocysteine levels in patients with essential hypertension.
Essential Hypertension
Fingertips ischemia, nephroangiosclerosis, and focal segmental glomerulosclerosis: is genetic thrombophilia the unique explanation?
Essential Hypertension
Functional Polymorphism rs13306560 of the MTHFR Gene Is Associated With Essential Hypertension in a Mexican-Mestizo Population.
Essential Hypertension
Hyperhomocysteinemia but not MTHFR genotype is associated with young-onset essential hypertension.
Essential Hypertension
Individual and Joint Associations of Methylenetetrahydrofolate Reductase C677T Genotype and Plasma Homocysteine With Dyslipidemia in a Chinese Population With Hypertension.
Essential Hypertension
Is there any genetic predisposition of MMP-9 gene C1562T and MTHFR gene C677T polymorphisms with essential hypertension?
Essential Hypertension
Methylenetetrahydrofolate reductase C677T gene polymorphism and essential hypertension: A meta-analysis of 10,415 subjects.
Essential Hypertension
Methylenetetrahydrofolate reductase gene polymorphisms in essential hypertension relation: with the development of hypertensive end-stage renal disease.
Essential Hypertension
Methylenetetrahydrofolate reductase polymorphism, type II diabetes mellitus, coronary artery disease, and essential hypertension in the Czech population.
Essential Hypertension
Polymorphism of MTHFR C677T Gene and the Associations with the Severity of Essential Hypertension in Northern Chinese Population.
Essential Hypertension
The 677 C/T MTHFR polymorphism is associated with essential hypertension, coronary artery disease, and higher homocysteine levels.
Essential Hypertension
The C677T polymorphism of the methylenetetrahydrofolate reductase gene is associated with the level of decrease on diastolic blood pressure in essential hypertension patients treated by angiotensin-converting enzyme inhibitor.
Essential Hypertension
The methylentetrahydrofolate reductase gene variant (C677T) as a risk factor for essential hypertension in Caucasians.
Essential Hypertension
The relationship between MTHFR C677T gene polymorphism and essential hypertension in a sample of an Algerian population of Oran city.
Essential Hypertension
[A case-control study on the relationship between abnormal homocysteine metabolism and essential hypertension]
Essential Hypertension
[Study of the genetic markers of thrombosis in hypertensive patients of the title population in the Republic of Mordovia]
Essential Tremor
Association of the C677T and A1298C polymorphisms of methylenetetrahydrofolate reductase gene in patients with essential tremor in Turkey.
Essential Tremor
Lack of association between methylenetetrahydrofolate reductase gene variants & essential tremor in Han Chinese.
Exfoliation Syndrome
MTHFR and MTHFD1 gene polymorphisms are not associated with pseudoexfoliation syndrome in South Indian population.
Factor XII Deficiency
Retinal vein occlusion in child with rare mutations in genes for thrombophilia.
Familial Mediterranean Fever
Do MTHFR mutations kick in during familial mediterranean fever attacks?
Fatty Liver
Associations between Methylenetetrahydrofolate Reductase (MTHFR) Polymorphisms and Non-Alcoholic Fatty Liver Disease (NAFLD) Risk: A Meta-Analysis.
Fatty Liver
Non-alcoholic fatty liver disease (NAFLD) and MTHFR 1298A > C gene polymorphism.
Fatty Liver
Plasmatic higher levels of homocysteine in non-alcoholic fatty liver disease (NAFLD).
Fatty Liver
The methylenetetrahydrofolate reductase genotype 677CT and non-alcoholic fatty liver disease have a synergistic effect on the increasing homocysteine levels in subjects from Chongqing, China.
Fatty Liver
[Association of hyperhomocysteinemia with liver steatosis in patients with chronic hepatitis C].
Fetal Alcohol Spectrum Disorders
High dietary folate in pregnant mice leads to pseudo-MTHFR deficiency and altered methyl metabolism, with embryonic growth delay and short-term memory impairment in offspring.
Fetal Alcohol Spectrum Disorders
High intake of folic acid disrupts embryonic development in mice.
Fetal Alcohol Spectrum Disorders
Moderate Folic Acid Supplementation in Pregnant Mice Results in Behavioral Alterations in Offspring with Sex-Specific Changes in Methyl Metabolism.
Fetal Death
Methylenetetrahydrofolate reductase C677T polymorphism and pregnancy complications.
Fetal Death
MTHFR (C677T) polymorphism and PR (PROGINS) mutation as genetic factors for preterm delivery, fetal death and low birth weight: A Northeast Indian population based study.
Fetal Death
MTHFR genetic polymorphism and the risk of intrauterine fetal death in Polish women.
Fetal Death
The investigation of hereditary and acquired thrombophilia risk factors in the development of complications in pregnancy in Croatian women.
Fetal Growth Retardation
Absence of association of thrombophilia polymorphisms with intrauterine growth restriction.
Fetal Growth Retardation
Association of MTHFR 677C>T polymorphism with IUGR and placental abruption risk: A systematic review and meta-analysis.
Fetal Growth Retardation
Association of MTHFR A1298C polymorphism (but not of MTHFR C677T) with elevated homocysteine levels and placental vasculopathies.
Fetal Growth Retardation
Carriage of the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism does not influence the first and second trimester uterine artery Doppler flow.
Fetal Growth Retardation
Combined heterozygosity for methylenetetrahydrofolate reductase (MTHFR) mutations C677T and A1298C is associated with abruptio placentae but not with intrauterine growth restriction.
Fetal Growth Retardation
Factor V Leiden, Prothrombin and MTHFR Mutation in Patients with Preeclamsia, Intrauterine Growth Restriction and Placental Abruption.
Fetal Growth Retardation
Familial thrombophilia and the occurrence of fetal growth restriction.
Fetal Growth Retardation
How strong is the association between maternal thrombophilia and adverse pregnancy outcome? A systematic review.
Fetal Growth Retardation
Inherited thrombophilia in pregnant women with intrauterine growth restriction.
Fetal Growth Retardation
Intrauterine growth restriction and genetic predisposition to thrombophilia.
Fetal Growth Retardation
Maternal methylenetetrahydrofolate reductase deficiency and low dietary folate lead to adverse reproductive outcomes and congenital heart defects in mice.
Fetal Growth Retardation
The association between maternal methylenetetrahydrofolate reductase C677T and A1298C polymorphism and birth defects and adverse pregnancy outcomes.
Fibromyalgia
Angiotensin converting enzyme and methylenetetrahydrofolate reductase gene variations in fibromyalgia syndrome.
Fibromyalgia
Investigation of ACE rs4646994, MTHFR rs1801133 and VDR rs2228570 Genotypes in Jordanian Patients with Fibromyalgia Syndrome.
Folic Acid Deficiency
A case report of branch retinal artery occlusion in a teenager due to hyperhomocysteinaemia; the interplay of genetic and nutritional defects.
Folic Acid Deficiency
Association of neural tube defects with maternal alterations and genetic polymorphisms in one-carbon metabolic pathway.
Folic Acid Deficiency
Effects of folic acid deficiency and MTHFR C677T polymorphism on spontaneous and radiation-induced micronuclei in human lymphocytes.
Folic Acid Deficiency
Factor V Leiden, prothrombin 20210A, methylenetetrahydrofolate reductase 677T, and population genetics.
Folic Acid Deficiency
Interactions Between MTHFR C677T - A1298C Variants and Folic Acid Deficiency Affect Breast Cancer Risk in a Chinese Population.
Folic Acid Deficiency
Lack of association of methylenetetrahydrofolate reductase 677C>T mutation with coronary artery disease in a Pakistani population.
Folic Acid Deficiency
Methylenetetrahydrofolate reductase C677T polymorphism, folic acid and riboflavin are important determinants of genome stability in cultured human lymphocytes.
Folic Acid Deficiency
Serum total homocysteine levels and the prevalence of folic acid deficiency and C677T mutation at the MTHFR gene in an indigenous population of Amazonia: the relationship of homocysteine with other cardiovascular risk factors.
Folic Acid Deficiency
The effect of folic acid deficiency and MTHFR C677T polymorphism on chromosome damage in human lymphocytes in vitro.
Folic Acid Deficiency
[Assessment of the sufficiency of Moscow population with folic acid, depending on the combined effect of polymorphism of MTHFR and FTO genes].
Folic Acid Deficiency
[Relationship of plasma homocysteine and folic acid levels and 5,10-methylenetetrahydrofolate reductase gene mutation with venous thromboembolism]
Foramen Ovale, Patent
Could genetic analysis be useful in reducing cerebrovascular risk in hypertensive subjects with hyperhomocysteinemia and patent foramen ovale? A 2-year follow-up study.
Foramen Ovale, Patent
Frequency of the C677T variant of the methylenetetrahydrofolate reductase (MTHFR) gene in patients with migraine with or without aura - a preliminary report.
Foramen Ovale, Patent
Stroke in Young Military Men With Heterozygous for MTHFR Gene Mutation or Factor V Leiden Gene Mutation Associated With Patent Foramen Ovale: Report of Two Cases and Therapeutic Strategy.
Gait Disorders, Neurologic
Rapidly progressive psychotic symptoms triggered by infection in a patient with methylenetetrahydrofolate reductase deficiency: a case report.
Gallbladder Neoplasms
Association of Methylenetetrahydrafolate Reductase Gene Polymorphism (MTHFR) in Patients with Gallbladder Cancer.
Gallbladder Neoplasms
No Association of Methylenetetrahydrofolate Reductase (MTHFR) C677T Polymorphism in Susceptibility to Gallbladder Cancer.
Gastritis, Atrophic
Association of MTHFR C677T polymorphism with severity and localization of chronic atrophic gastritis patients without Helicobacter pylori infection: a case control study.
Gastritis, Atrophic
Homocysteine Levels in Chronic Gastritis and Other Conditions: Relations to Incident Cardiovascular Disease and Dementia.
Gastritis, Atrophic
MTHFR polymorphisms involved in vitamin B12 deficiency associated with atrophic gastritis.
Gastrointestinal Diseases
[677T mutation of the MTHFR gene in adenomas and colorectal cancer in a population sample from the Northeastern Mexico. Preliminary results]
Gastrointestinal Neoplasms
Effect of MTHFR Polymorphisms on Gastrointestinal Cancer Risk in Italy.
Gastrointestinal Neoplasms
Influence of FPGS, ABCC4, SLC29A1, and MTHFR genes on the pharmacogenomics of fluoropyrimidines in patients with gastrointestinal cancer from the Brazilian Amazon.
Gastrointestinal Neoplasms
Methylenetetrahydrofolate reductase polymorphism is associated with folate pool in gastrointestinal cancer tissue.
Gastrointestinal Neoplasms
Polymorphisms in folic acid metabolism genes do not associate with cancer cachexia in Japanese gastrointestinal patients.
Gastrointestinal Neoplasms
The combination of methylenehydrofolate reductase C677T polymorphism screening and gastrointestinal tumor markers detection may be an early screening method for gastrointestinal cancer related to helicobacter pylori infection.
Gastroschisis
Effects of MTHFR c.677C>T, F2 c.20210G>A and F5 Leiden Polymorphisms in Gastroschisis.
Gastroschisis
Genetic predispositions for thromboembolism as a possible etiology for gastroschisis.
Gaucher Disease
A newborn case with perinatal-lethal Gaucher disease due to R463H homozygosity complicated by C677T homozygosity in the MTHFR gene.
Genetic Diseases, Inborn
Methylenetetrahydrofolate reductase polymorphisms and risk of sporadic and hereditary colorectal cancer with or without microsatellite instability.
Genetic Diseases, Inborn
Whole genome sequencing identifies ANXA3 and MTHFR mutations in a large family with an unknown equinus deformity associated genetic disorder.
Genetic Diseases, Inborn
[No association between MTHFR 677C>T polymorphism and ovarian cancer risk in BRCA1 mutation carriers in Wielkopolska region].
Gestational Trophoblastic Disease
667C>T and 1298A>C polymorphisms of MTHFR do not predict response to methotrexate in patients with gestational trophoblastic neoplasia.
Gestational Trophoblastic Disease
Presence of the methylenetetrahydrofolate reductase gene polymorphism MTHFR C677T in molar tissue but not maternal blood predicts failure of methotrexate treatment for low-risk gestational trophoblastic neoplasia.
Glaucoma
Association of MTHFR C677T and A1298C Polymorphisms with Glaucoma Risk: a Systematic Review Meta-Analysis based 42 Case-Control Studies.
Glaucoma
Association of MTHFR C677T polymorphism with primary open angle glaucoma: a Meta-analysis based on 18 case-control studies.
Glaucoma
Association of the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism with primary glaucoma in Saudi population.
Glaucoma
C677T polymorphism in the methylenetetrahydrofolate reductase gene is associated with primary closed angle glaucoma.
Glaucoma
Lack of Association between the C677T Single Nucleotide Polymorphism of the MTHFR Gene and Glaucoma in Iranian Patients.
Glaucoma
Methylenetetrahydrofolate reductase 677 C-T and homocysteine levels in Turkish patients with pseudoexfoliation.
Glaucoma
Methylenetetrahydrofolate reductase gene polymorphisms c.677C/T and c.1298A/C are not associated with open angle glaucoma.
Glaucoma
Methylenetetrahydrofolate reductase genetic polymorphisms in patients with primary open-angle glaucoma.
Glaucoma
MTHFR C677T predisposes to POAG but not to PACG in a North Indian population: a case control study.
Glaucoma
MTHFR gene C677T and A1298C polymorphisms and homocysteine levels in primary open angle and primary closed angle glaucoma.
Glaucoma
Plasma homocysteine, serum folic acid, serum vitamin B12, serum vitamin B6, MTHFR and risk of pseudoexfoliation glaucoma: a meta-analysis.
Glaucoma
Plasma Homocysteine, Serum Folic Acid, Serum Vitamin B12, Serum Vitamin B6, MTHFR, and Risk of Normal-Tension Glaucoma.
Glaucoma
The C677T variant in the methylenetetrahydrofolate reductase gene is not associated with disease in cohorts of pseudoexfoliation glaucoma and primary open-angle glaucoma patients from Iowa.
Glaucoma, Angle-Closure
Association of the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism with primary glaucoma in Saudi population.
Glaucoma, Angle-Closure
C677T polymorphism in the methylenetetrahydrofolate reductase gene is associated with primary closed angle glaucoma.
Glaucoma, Angle-Closure
MTHFR C677T predisposes to POAG but not to PACG in a North Indian population: a case control study.
Glaucoma, Open-Angle
Association between MTHFR C677T polymorphism and primary open-angle glaucoma: a meta-analysis.
Glaucoma, Open-Angle
Association of MTHFR C677T and A1298C Polymorphisms with Glaucoma Risk: a Systematic Review Meta-Analysis based 42 Case-Control Studies.
Glaucoma, Open-Angle
Association of MTHFR C677T polymorphism with primary open angle glaucoma: a Meta-analysis based on 18 case-control studies.
Glaucoma, Open-Angle
Association of the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism with primary glaucoma in Saudi population.
Glaucoma, Open-Angle
C677T polymorphism in the methylenetetrahydrofolate reductase gene is associated with primary closed angle glaucoma.
Glaucoma, Open-Angle
Homocysteine, B Vitamins, Methylenetetrahydrofolate Reductase Gene, and Risk of Primary Open-Angle Glaucoma: A Meta-analysis.
Glaucoma, Open-Angle
Methylenetetrahydrofolate reductase gene polymorphisms c.677C/T and c.1298A/C are not associated with open angle glaucoma.
Glaucoma, Open-Angle
Methylenetetrahydrofolate reductase genetic polymorphisms in patients with primary open-angle glaucoma.
Glaucoma, Open-Angle
MTHFR C677T homozygous mutation in a patient with pigmentary glaucoma and central retinal vein occlusion.
Glaucoma, Open-Angle
MTHFR C677T predisposes to POAG but not to PACG in a North Indian population: a case control study.
Glaucoma, Open-Angle
MTHFR gene C677T and A1298C polymorphisms and homocysteine levels in primary open angle and primary closed angle glaucoma.
Glaucoma, Open-Angle
The C677T variant in the methylenetetrahydrofolate reductase gene is not associated with disease in cohorts of pseudoexfoliation glaucoma and primary open-angle glaucoma patients from Iowa.
Glaucoma, Open-Angle
The Effect of MTHFR Ala222Val Polymorphism on Open-angle Glaucoma: A Meta-analysis.
Glioblastoma
Genome-wide Hypomethylation in Human Glioblastomas Associated with Specific Copy Number Alteration, Methylenetetrahydrofolate Reductase Allele Status, and Increased Proliferation.
Glioblastoma
Intranasal perillyl alcohol therapy improves survival of patients with recurrent glioblastoma harboring mutant variant for MTHFR rs1801133 polymorphism.
Glioblastoma
The methionine synthase polymorphism c.2756A>G alters susceptibility to glioblastoma multiforme.
Glioblastoma
The methylenetetrahydrofolate reductase (MTHFR) variant c.677C>T (A222V) influences overall survival of patients with glioblastoma multiforme.
Glioma
ACE I/D sequence variants but not MTHFR C677T, is strongly linked to malignant glioma risk and its variant DD genotype may act as a promising predictive biomarker for overall survival of glioma patients.
Glioma
Association between MTHFR 677C>T polymorphism and risk of gliomas: evidence from a meta-analysis.
Glioma
C677T gene polymorphism of methylenetetrahydrofolate reductase (MTHFR) in meningiomas and high-grade gliomas.
Glioma
Folate metabolism genetic polymorphisms and meningioma and glioma susceptibility in adults.
Glioma
Functional polymorphisms in folate metabolism genes influence the risk of meningioma and glioma.
Glioma
Impact of MTHFR polymorphisms on methylation of MGMT in glioma patients from Northeast China with different folate levels.
Glioma
MTHFR C677T and A1298C Polymorphisms in Breast Cancer, Gliomas and Gastric Cancer: A Review.
Glioma
Polo-like kinase 1 (PLK1)-dependent phosphorylation of methylenetetrahydrofolate reductase (MTHFR) regulates replication via histone methylation.
Glomerulonephritis, Membranous
Arterial thrombosis associated with factor V Leiden and methylenetetrahydrofolate reductase C677T mutation in childhood membranous glomerulonephritis.
Glomerulonephritis, Membranous
Cerebral sinovenous thrombosis associated with factor V Leiden and methylenetetrahydrofolate reductase A1298C mutation in adult membranous glomerulonephritis.
Glomerulosclerosis, Focal Segmental
METHYLENETETRAHYDROFOLATE REDUCTASE C677T POLYMORPHISM IN PATIENTS WITH HENOCH-SCHÖNLEIN PURPURA.
Glomerulosclerosis, Focal Segmental
Methylenetetrahydrofolate reductase polymorphism in childhood primary focal segmental glomerulosclerosis.
Glucose Intolerance
A comparison of the genetic and clinical risk factors for arterial hypertension between indigenous and non-indigenous people of the Shoria Mountain Region.
Glucose Intolerance
Association of Methylene Tetrahydrofolate Reductase C677T Genotype With Type 2 Diabetes Mellitus Patients With and Without Renal Complications.
glucose-6-phosphate dehydrogenase (nadp+) deficiency
The prevalence of factor V Leiden, prothrombin G20210A and methylenetetrahydrofolate reductase polymorphism C677T among G6PD deficient individuals from Western Iran.
Glucosephosphate Dehydrogenase Deficiency
The prevalence of factor V Leiden, prothrombin G20210A and methylenetetrahydrofolate reductase polymorphism C677T among G6PD deficient individuals from Western Iran.
glutamate formimidoyltransferase deficiency
Update and new concepts in vitamin responsive disorders of folate transport and metabolism.
Graft vs Host Disease
Decreased risk of acute graft-versus-host disease following allogeneic hematopoietic stem cell transplantation in patients with the 5,10-methylenetetrahydrofolate reductase 677TT genotype.
Graft vs Host Disease
Donor methylenetetrahydrofolate reductase genotype is associated with graft-versus-host disease in hematopoietic stem cell transplant patients treated with methotrexate.
Graft vs Host Disease
Methylenetetrahydrofolate reductase and thymidylate synthase genotypes and risk of acute graft-versus-host disease following hematopoietic cell transplantation for chronic myelogenous leukemia.
Graft vs Host Disease
The Effect of Folinic Acid on Methylenetetrahydrofolate Reductase Polymorphisms in Methotrexate-Treated Allogeneic Hematopoietic Stem Cell Transplants.
Graves Disease
Association between methylenetetrahydrofolate reductase (MTHFR) polymorphisms and susceptibility to Graves' ophthalmopathy.
Graves Disease
Association study between methylenetetrahydrofolate reductase gene polymorphisms and Graves' disease.
guanidinoacetate n-methyltransferase deficiency
Targeted cerebrospinal fluid analysis for inborn errors of metabolism on an LC-MS/MS analysis platform.
Gyrate Atrophy
Targeted cerebrospinal fluid analysis for inborn errors of metabolism on an LC-MS/MS analysis platform.
Hamartoma
Are the methylenetetrahydrofolate reductase 1298 and 677 gene polymorphisms related to optic glioma and hamartoma risk in neurofibromatosis type 1 patients?
Hand-Foot Syndrome
Association of C677T and A1298C MTHFR Polymorphisms and Fluoropyrimidine-induced Toxicity in Mestizo Patients With Metastatic Colorectal Cancer.
Hand-Foot Syndrome
Evaluation of 5-fluorouracil degradation rate and Pharmacogenetic profiling to predict toxicity following adjuvant Capecitabine.
Hand-Foot Syndrome
Polymorphisms of MTHFR and TYMS predict capecitabine-induced hand-foot syndrome in patients with metastatic breast cancer.
Head and Neck Neoplasms
Head and neck cancer susceptibility: a genetic marker in the methylenetetrahydrofolate reductase gene.
Head and Neck Neoplasms
Meta-analyses of the methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and risk of head and neck and lung cancer.
Head and Neck Neoplasms
MTHFR C677T gene polymorphism and head and neck cancer risk: a meta-analysis based on 23 publications.
Head and Neck Neoplasms
MTHFR C677T polymorphism interaction with heavy alcohol consumption increases head and neck carcinoma risk.
Head and Neck Neoplasms
No association between MTHFR A1298C gene polymorphism and head and neck cancer risk: a meta-analysis based on 9,952 subjects.
Head and Neck Neoplasms
Polymorphisms and haplotypes in methylenetetrahydrofolate reductase gene and head and neck squamous cell carcinoma risk.
Headache Disorders, Primary
Genes and primary headaches: discovering new potential therapeutic targets.
Hearing Loss
MTHFR 677T is a strong determinant of the degree of hearing loss among Polish males with postlingual sensorineural hearing impairment.
Hearing Loss
Prothrombotic gene mutations in patients with sudden sensorineural hearing loss and cardiovascular thrombotic disease.
Hearing Loss, Sensorineural
Association between the methylenetetrahydrofolate reductase gene C677T polymorphism and sudden sensorineural hearing loss: a meta-analysis.
Hearing Loss, Sensorineural
Association of the C677T polymorphism in the methylenetetrahydrofolate reductase gene with sudden sensorineural hearing loss.
Hearing Loss, Sensorineural
Impact of Methionine Synthase Gene and Methylenetetrahydrofolate Reductase Gene Polymorphisms on the Risk of Sudden Sensorineural Hearing Loss.
Hearing Loss, Sensorineural
Methylenetetrahydrofolate reductase C677T gene mutation as risk factor for sudden sensorineural hearing loss: association with plasma homocysteine, folate and cholesterol concentrations.
Hearing Loss, Sensorineural
MTHFR AND ApoE genetic variants association with sudden sensorineural hearing loss.
Hearing Loss, Sensorineural
Prothrombotic gene mutations in patients with sudden sensorineural hearing loss and cardiovascular thrombotic disease.
Hearing Loss, Sensorineural
Role of Genetic and Acquired Prothrombotic Risk Factors in Genesis of Sudden Sensorineural Hearing Loss.
Hearing Loss, Sensorineural
Sudden sensorineural hearing loss: A vascular cause? Analysis of prothrombotic risk factors in head and neck.
Hearing Loss, Sudden
Methylenetetrahydrofolate reductase gene mutations as risk factors for sudden hearing loss.
Heart Defects, Congenital
A probe directed recombinase amplification assay for detection of MTHFR A1298C polymorphism associated with congenital heart disease.
Heart Defects, Congenital
Are polymorphisms in MTRR A66G and MTHFR C677T genes associated with congenital heart diseases in Iranian population?
Heart Defects, Congenital
Association analysis between MTHFR genetic polymorphisms and the risk of congenital heart diseases in Chinese Han population.
Heart Defects, Congenital
Association analysis of maternal MTHFR gene polymorphisms and the occurrence of congenital heart disease in offspring.
Heart Defects, Congenital
Association between 5, 10-methylenetetrahydrofolate reductase (MTHFR) polymorphisms and congenital heart disease: A meta-analysis.
Heart Defects, Congenital
Association Between MTHFR C677T Polymorphism and Congenital Heart Disease.
Heart Defects, Congenital
Association between MTHFR C677T polymorphism and congenital heart disease. A family-based meta-analysis.
Heart Defects, Congenital
Association between MTHFR polymorphisms and congenital heart disease: a meta-analysis based on 9,329 cases and 15,076 controls.
Heart Defects, Congenital
Association of congenital cardiac defects and the C677T methylenetetrahydrofolate reductase polymorphism.
Heart Defects, Congenital
Association of the C677T methylenetetrahydrofolate reductase mutation with congenital heart diseases.
Heart Defects, Congenital
Congenital heart defects, maternal homocysteine, smoking, and the 677 C>T polymorphism in the methylenetetrahydroflate reductase gene: evaluating gene-environment interactions.
Heart Defects, Congenital
Correlation Between Methyltetrahydrofolate Reductase (MTHFR) Polymorphisms and Isolated Patent Ductus Arteriosus in Taiwan.
Heart Defects, Congenital
Evaluation of C677T and A1298C polymorphisms of the MTHFR gene as maternal risk factors for Down syndrome and congenital heart defects.
Heart Defects, Congenital
Evaluation of High Resolution Melting for MTHFR C677T Genotyping in Congenital Heart Disease.
Heart Defects, Congenital
Fission Yeast Methylenetetrahydrofolate Reductase Ensures Mitotic and Meiotic Chromosome Segregation Fidelity.
Heart Defects, Congenital
Genetic polymorphism of methylenetetrahydrofolate reductase as a potential risk factor for congenital heart disease: A meta-analysis in Chinese pediatric population.
Heart Defects, Congenital
Homocysteine concentrations and molecular analysis in patients with congenital heart defects.
Heart Defects, Congenital
Hyperhomocysteinemia and MTHFR polymorphisms in association with orofacial clefts and congenital heart defects: a meta-analysis.
Heart Defects, Congenital
Infant methylenetetrahydrofolate reductase 677TT genotype is a risk factor for congenital heart disease.
Heart Defects, Congenital
Lack of evidence of association between MTHFR C677T polymorphism and congenital heart disease in a TDT study design.
Heart Defects, Congenital
Maternal and offspring MTHFR gene C677T polymorphism as predictors of congenital atrial septal defect and patent ductus arteriosus.
Heart Defects, Congenital
Maternal folate deficiency affects proliferation, but not apoptosis, in embryonic mouse heart.
Heart Defects, Congenital
Maternal methylenetetrahydrofolate reductase deficiency and low dietary folate lead to adverse reproductive outcomes and congenital heart defects in mice.
Heart Defects, Congenital
Maternal MTHFR 677C>T is a risk factor for congenital heart defects: effect modification by periconceptional folate supplementation.
Heart Defects, Congenital
Maternal MTHFR C677T polymorphism and congenital heart defect risk in the Chinese Han population: a meta-analysis.
Heart Defects, Congenital
Meta analysis of the association between MTHFR C677T polymorphism and the risk of congenital heart defects.
Heart Defects, Congenital
Meta-Prediction of MTHFR Gene Polymorphism and Air Pollution on the Risks of Congenital Heart Defects Worldwide: A Transgenerational Analysis.
Heart Defects, Congenital
Methylene tetrahydrofolate reductase polymorphisms and homocysteine level in heart defects.
Heart Defects, Congenital
Methylenetetrahydrofolate reductase C677T polymorphism and congenital heart disease: a meta-analysis.
Heart Defects, Congenital
Methylenetetrahydrofolate Reductase C677T: Hypoplastic Left Heart and Thrombosis.
Heart Defects, Congenital
Methylenetetrahydrofolate reductase gene 677CT polymorphism and isolated congenital heart disease in a Mexican population.
Heart Defects, Congenital
MTHFR A1298C polymorphisms reduce the risk of congenital heart defects: a meta-analysis from 16 case-control studies.
Heart Defects, Congenital
MTHFR C677T and A1298C gene polymorphisms and their relation to homocysteine level in Egyptian children with congenital heart diseases.
Heart Defects, Congenital
MTHFR C677T and A1298C polymorphisms as a risk factor for congenital heart defects in Down syndrome.
Heart Defects, Congenital
MTHFR C677T Polymorphism and Risk of Congenital Heart Defects: Evidence from 29 Case-Control and TDT Studies.
Heart Defects, Congenital
MTHFR polymorphisms in Puerto Rican children with isolated congenital heart disease and their mothers.
Heart Defects, Congenital
MTHFR promoter hypermethylation may lead to congenital heart defects in Down syndrome.
Heart Defects, Congenital
Non-optimal maturation of the oocyte, maternal MTHFR polymorphisms, periconceptional folate, and decrease of congenital heart defects.
Heart Defects, Congenital
Parental Genetic Variants, MTHFR 677C>T and MTRR 66A>G, Associated Differently with Fetal Congenital Heart Defect.
Heart Defects, Congenital
Polymorphism 677C?T MTHFR Gene in Mexican Mothers of Children With Complex Congenital Heart Disease.
Heart Defects, Congenital
Risk factors and methylenetetrahydrofolate reductase gene in congenital heart disease.
Heart Defects, Congenital
Study on Environmental Causes and SNPs of MTHFR, MS and CBS Genes Related to Congenital Heart Disease.
Heart Defects, Congenital
Study on Maternal SNPs of MTHFR Gene and HCY Level Related to Congenital Heart Diseases.
Heart Defects, Congenital
The association between c.1333C?>?T genetic polymorphism of MTHFR gene and the risk of congenital heart diseases.
Heart Defects, Congenital
The association between maternal methylenetetrahydrofolate reductase C677T and A1298C polymorphism and birth defects and adverse pregnancy outcomes.
Heart Defects, Congenital
The association of the MTHFR c.1625A>C genetic variant with the risk of congenital heart diseases in the Chinese.
Heart Defects, Congenital
The methylenetetrahydrofolate reductase gene variant (C677T) as a susceptibility gene for tetralogy of Fallot.
Heart Defects, Congenital
The MTHFR 677C->T polymorphism and the risk of congenital heart defects: a literature review and meta-analysis.
Heart Defects, Congenital
The roles of MTRR and MTHFR gene polymorphisms in congenital heart diseases: a meta-analysis.
Heart Defects, Congenital
Two Common MTHFR Gene Polymorphisms (C677T and A1298C) and Fetal Congenital Heart Disease Risk: An Updated Meta-Analysis with Trial Sequential Analysis.
Heart Defects, Congenital
[A case-control study on congenital heart diseases with methylenetetrahydrofolate reductase gene, cystathionine beta-synthase gene, and environmental factors]
Heart Defects, Congenital
[Correlation between offspring congenital heart disease and MTHFR 677C/T polymorphism and general status of pregnant women].
Heart Defects, Congenital
[Correlationship between congenital heart disease and polymorphism of MTHFR gene].
Heart Defects, Congenital
[Study of correlationship between congenital heart disease and 5, 10-methylenetetra hydrofolate reductase gene's polymorphism or folacin intakes]
Heart Diseases
Association of methylenetetrahydrofolate reductase gene C677T polymorphism with polycystic ovary syndrome risk: a systematic review and meta-analysis update.
Heart Diseases
Clinical presentation, etiology, and outcome of stroke in children: A hospital-based study.
Heart Diseases
Decreased expression of methylene tetrahydrofolate reductase (MTHFR) gene in patients with rheumatoid arthritis.
Heart Diseases
Family-based investigation of the C677T polymorphism of the methylenetetrahydrofolate reductase gene in ischaemic heart disease.
Heart Diseases
Increased Resistance to Malaria in Mice with Methylenetetrahydrofolate Reductase (Mthfr) Deficiency Suggests a Mechanism for Selection of the MTHFR 677C>T (c.665C>T) Variant.
Heart Diseases
Lack of association between methylenetetrahydrofolate reductase (MTHFR) C677T and ischaemic heart disease (IHD): family-based association study in a Spanish population.
Heart Diseases
MTHFR c.1793G>A polymorphism is associated with congenital cardiac disease in a Chinese population.
Heart Diseases
Sequence Variation of the Methylene Tetrahydrofolate Reductase Gene (677C>T and 1298?A>C) and Traditional Risk Factors in a South Indian Population.
Heart Diseases
The dose-response relation between serum homocysteine and cardiovascular disease: implications for treatment and screening.
Heart Failure
Biventricular Thrombi in a Patient With Heart Failure With Severely Reduced Ejection Fraction and Heterozygous Prothrombin 20210G/A and Homozygous Methylenetetrahydrofolate Reductase 677C/T Mutations.
Heart Septal Defects, Atrial
Genomics and Epigenomics of Congenital Heart Defects: Expert Review and Lessons Learned in Africa.
Heart Septal Defects, Atrial
Maternal and offspring MTHFR gene C677T polymorphism as predictors of congenital atrial septal defect and patent ductus arteriosus.
Heart Septal Defects, Atrial
Secundum atrial septal defects and methylenetetrahydrofolate reductase C677T polymorphism: A special category of ASDs?
Heart Septal Defects, Ventricular
Analysis of MTHFR and MTRR Gene Polymorphisms in Iranian Ventricular Septal Defect Subjects.
Heart Septal Defects, Ventricular
Genomics and Epigenomics of Congenital Heart Defects: Expert Review and Lessons Learned in Africa.
Heart Septal Defects, Ventricular
MTHFR c.1793G>A polymorphism is associated with congenital cardiac disease in a Chinese population.
HELLP Syndrome
High frequency of methylenetetrahydrofolate reductase 677TT genotype in Hungarian HELLP syndrome patients determined by quantitative real-time PCR.
HELLP Syndrome
Maternal factor V Leiden mutation is associated with HELLP syndrome in Caucasian women.
HELLP Syndrome
Methylenetetrahydrofolate reductase polymorphisms in preeclampsia and the HELLP syndrome.
HELLP Syndrome
PP004. Study of the methylenetetrahydrofolate reductase and the reduced-folate carrier-1 gene polymorphism in healthy and severe pre-eclamptic patients.
Hematologic Diseases
Decreased risk of acute graft-versus-host disease following allogeneic hematopoietic stem cell transplantation in patients with the 5,10-methylenetetrahydrofolate reductase 677TT genotype.
Hematologic Diseases
Role of MTHFR (677, 1298) haplotype in the risk of developing secondary leukemia after treatment of breast cancer and hematological malignancies.
Hematologic Neoplasms
Folate restriction and methylenetetrahydrofolate reductase 677T polymorphism decreases adoMet synthesis via folate-dependent remethylation in human-transformed lymphoblasts.
Hematologic Neoplasms
MTHFR gene polymorphisms and methotrexate toxicity in adult patients with hematological malignancies: a meta-analysis.
Hematologic Neoplasms
Pharmacogenetics of methotrexate in pediatric hematological neoplasm treatment: does it need a personalized regimen based on MTHFR polymorphisms?
Hematologic Neoplasms
Regulation of Folate-Mediated One-Carbon Metabolism by Glycine N-Methyltransferase (GNMT) and Methylenetetrahydrofolate Reductase (MTHFR).
Hematologic Neoplasms
Role of MTHFR (677, 1298) haplotype in the risk of developing secondary leukemia after treatment of breast cancer and hematological malignancies.
Hematologic Neoplasms
The influence of MTHFR genetic polymorphisms on adverse reactions after methotrexate in patients with hematological malignancies: a meta-analysis.
Hematologic Neoplasms
The relationship between methylenetetrahydrofolate reductase polymorphism and hematological malignancy.
Hematologic Neoplasms
The role of MTHFR and RFC1 polymorphisms on toxicity and outcome of adult patients with hematological malignancies treated with high-dose methotrexate followed by leucovorin rescue.
Hematologic Neoplasms
[A new method for 5, 10-methylenetetrahydrofolate reductase single nucleotide polymorphisms genotyping used to study susceptibility of hematological malignancy]
Hematologic Neoplasms
[PROVISIONAL] The differential effects of the methylenetetrahydrofolate reductase polymorphisms (C677T and A1298C) on hematological malignancies among Latinos: a meta-analysis.
Hemochromatosis
Genotyping of single-nucleotide polymorphisms by high-resolution melting of small amplicons.
Hemochromatosis
Prediction of features of the course of chronic hepatitis C using Bayesian networks.
Hemoglobinuria
Budd-Chiari syndrome in a paroxysmal nocturnal hemoglobinuria patient with coexistence of factor II and MTHFR mutations.
Hemoglobinuria, Paroxysmal
Budd-Chiari syndrome in a paroxysmal nocturnal hemoglobinuria patient with coexistence of factor II and MTHFR mutations.
Hemolytic-Uremic Syndrome
Postoperative Symptomatic Cerebral Infarction in Pediatric Moyamoya Disease: Risk Factors and Clinical Outcome.
Hemolytic-Uremic Syndrome
The TT genotype of the C677T polymorphism in the methylentetrahydrofolate reductase as a risk factor in thrombotic microangiopathies: results from a pilot study.
Hemophilia A
Clinical variability of haemophilia A and B in Mexican families by factor V Leiden G1691A, prothrombin G20210A and MTHFR C677T/A1298C.
Hemophilia A
Does the MTHFR 677T allele alter the clinical phenotype in severe haemophilia A?
Hemophilia A
Effect of Prothrombotic Mutations on Factor Consumption in Children With Hemophilia.
Hemophilia A
Haemophilia and thrombophilia. What do we learn about combined inheritance of both genetic variations?
Hemophilia A
Impact of Prothrombotic Risk Factors in a Cohort of Egyptian Hemophilia A Patients.
Hemophilia A
The Impact of Prothrombotic Mutations on Factor Consumption in Adult Patients With Severe Hemophilia.
Hemorrhagic Stroke
Association of the C677T Polymorphism in the MTHFR Gene with Hemorrhagic Stroke: A Meta-Analysis.
Hemorrhagic Stroke
Evaluation of MTHFR C677T polymorphism in ischemic and hemorrhagic stroke patients. A case-control study in a Northern Indian population.
Hemorrhagic Stroke
Methylenetetrahydrofolate Reductase Gene Polymorphisms (C677T and A1298C) and Hemorrhagic Stroke in Moroccan Patients.
Hemorrhagic Stroke
Methylenetetrahydrofolate reductase gene polymorphisms are associated with ischemic and hemorrhagic stroke: Dual effect of MTHFR polymorphisms C677T and A1298C.
Hemorrhagic Stroke
Prospective study of first stroke in relation to plasma homocysteine and MTHFR 677C>T and 1298A>C genotypes and haplotypes - evidence for an association with hemorrhagic stroke.
Hemorrhagic Stroke
Quantitative assessment of the association between MTHFR C677T polymorphism and hemorrhagic stroke risk.
Hemorrhagic Stroke
Relationship between methylenetetrahydrofolate reductase (MTHFR) gene (A1298C) polymorphism with the risk of stroke: A systematic review and meta-analysis.
Hemostatic Disorders
[Association of hemostatic disorders in diabetic patients with methylenetetrahydrofolate reductase (C677T) and coagulation factors II (G20210A) and V (G1691A) gene polymorphism].
Hepatic Veno-Occlusive Disease
MTHFR C677T/A1298C genotype: a possible risk factor for liver sinusoidal obstruction syndrome.
Hepatic Veno-Occlusive Disease
TPMT and MTHFR genotype is not associated with altered risk of thioguanine-related sinusoidal obstruction syndrome in pediatric acute lymphoblastic leukemia: A report from the Children's Oncology Group.
Hepatitis
Associations between MTHFR Ala222Val polymorphism and risks of hepatitis and hepatitis-related liver cancer: a meta-analysis.
Hepatitis
Hyperhomocysteinaemia in chronic liver diseases: role of disease stage, vitamin status and methylenetetrahydrofolate reductase genetics.
Hepatitis B
Methylenetetrahydrofolate reductase (MTHFR) and methionine synthase reductase (MTRR) gene polymorphisms as risk factors for hepatocellular carcinoma in a Korean population.
Hepatitis B
PAI-1 4G-4G and MTHFR 677TT in non-hepatitis C virus/hepatitis B virus-related liver cirrhosis.
Hepatitis C
Homocysteine levels and sustained virological response to pegylated-interferon alpha2b plus ribavirin therapy for chronic hepatitis C: a prospective study.
Hepatitis C
Methylenetetrahydrofolate Reductase (MTHFR) C677T polymorphism and high plasma homocysteine in Chronic Hepatitis C (CHC) infected patients from the Northeast of Brazil.
Hepatitis C
Methylenetetrahydrofolate reductase C677T polymorphism and liver fibrosis progression in patients with recurrent hepatitis C.
Hepatitis C
Methylenetetrahydrofolate reductase homozygosis and low-density lipoproteins in patients with genotype 1 chronic hepatitis C.
Hepatitis C
PAI-1 4G-4G and MTHFR 677TT in non-hepatitis C virus/hepatitis B virus-related liver cirrhosis.
Hepatitis C
Possible roles of methylenetetrahydrofolate reductase polymorphism and folate status in patients with early hepatitis C virus genotype 4.
Hepatitis C, Chronic
Homocysteine levels and sustained virological response to pegylated-interferon alpha2b plus ribavirin therapy for chronic hepatitis C: a prospective study.
Hepatitis C, Chronic
Hyperhomocysteinemia and the MTHFR C677T polymorphism promote steatosis and fibrosis in chronic hepatitis C patients.
Hepatitis C, Chronic
Methylenetetrahydrofolate Reductase (MTHFR) C677T polymorphism and high plasma homocysteine in Chronic Hepatitis C (CHC) infected patients from the Northeast of Brazil.
Hepatitis C, Chronic
Methylenetetrahydrofolate reductase C677T polymorphism and liver fibrosis progression in patients with recurrent hepatitis C.
Hepatitis C, Chronic
Methylenetetrahydrofolate reductase homozygosis and low-density lipoproteins in patients with genotype 1 chronic hepatitis C.
Hepatitis C, Chronic
MTHFR rs1801133 Polymorphism Is Associated With Liver Fibrosis Progression in Chronic Hepatitis C: A Retrospective Study.
Hepatitis C, Chronic
[Endothelial dysfunction gene polymorphisms and the rate of liver fibrosis in chronic hepatitis C].
Hepatitis C, Chronic
[Mathematic Model for Prediction of Liver Fibrosis Progression Rate in Patients with Chronic Hepatitis C Based on Combination of Genomic Markers].
Hepatolenticular Degeneration
Genetic variability in the methylenetetrahydrofolate reductase gene (MTHFR) affects clinical expression of Wilson's Disease.
Hereditary Angioedema Type III
Hereditary angioedema type III, recurrent pregnancy loss and heterozygous MTHFR mutation.
Hereditary Angioedema Types I and II
Management of hereditary angioedema type I and homozygous MTHFR mutation during pregnancy.
Herpes Simplex
Evaluation of etiology and pregnancy outcome in recurrent miscarriage patients.
Hirschsprung Disease
Acute complete splenic infarction in a patient with Hirschsprung's disease and literature review of complete splenic infarction.
Hodgkin Disease
Nutrients and Genetic Variation Involved in One-Carbon Metabolism and Hodgkin Lymphoma Risk: A Population-based Case-Control Study.
Homocystinuria
Acute stroke in relation to homocysteine and methylenetetrahydrofolate reductase gene polymorphisms.
Homocystinuria
Betaine for treatment of homocystinuria caused by methylenetetrahydrofolate reductase deficiency.
Homocystinuria
Betaine rescue of an animal model with methylenetetrahydrofolate reductase deficiency.
Homocystinuria
Characterization of mutations in severe methylenetetrahydrofolate reductase deficiency reveals an FAD-responsive mutation.
Homocystinuria
Characterization of six novel mutations in the methylenetetrahydrofolate reductase (MTHFR) gene in patients with homocystinuria.
Homocystinuria
Clinical presentation, etiology, and outcome of stroke in children: A hospital-based study.
Homocystinuria
Coexistence of Neurofibromatosis Type-1 and MTHFR C677T Gene Mutation in a Young Stroke Patient: A Case Report.
Homocystinuria
Complete deficiency of methylenetetrahydrofolate reductase in mice is associated with impaired retinal function and variable mortality, hematological profiles, and reproductive outcomes.
Homocystinuria
Detection of homozygotes and heterozygotes with methylenetetrahydrofolate reductase deficiency.
Homocystinuria
Epidemiology of rare diseases detected by newborn screening in the Czech Republic.
Homocystinuria
Folic acid nonresponsive homocystinuria due to methylenetetrahydrofolate reductase deficiency.
Homocystinuria
Functional characterization of missense mutations in severe methylenetetrahydrofolate reductase deficiency using a human expression system.
Homocystinuria
Genomic structure and transcript variants of the human methylenetetrahydrofolate reductase gene.
Homocystinuria
High dietary folate in pregnant mice leads to pseudo-MTHFR deficiency and altered methyl metabolism, with embryonic growth delay and short-term memory impairment in offspring.
Homocystinuria
Homocystinuria associated with decreased methylenetetrahydrofolate reductase activity.
Homocystinuria
Homocystinuria Due to MTHFR Variant Presenting As Infantile Tremor Syndrome.
Homocystinuria
Homozygous cystathionine beta-synthase deficiency, combined with factor V Leiden or thermolabile methylenetetrahydrofolate reductase in the risk of venous thrombosis.
Homocystinuria
Hydrocephalus internus in two patients with 5,10-methylenetetrahydrofolate reductase deficiency.
Homocystinuria
Inborn Errors of Metabolism Associated With Autism Spectrum Disorders: Approaches to Intervention.
Homocystinuria
Intermediate hyperhomocysteinaemia and compound heterozygosity for the common variant c.677C>T and a MTHFR gene mutation.
Homocystinuria
Life-threatening methylenetetrahydrofolate reductase (MTHFR) deficiency with extremely early onset: Characterization of two novel mutations in compound heterozygous patients.
Homocystinuria
Mefolinate (5-methyltetrahydrofolate), but not folic acid, decreases mortality in an animal model of severe methylenetetrahydrofolate reductase deficiency.
Homocystinuria
Methylenetetrahydrofolate reductase deficiency: importance of early diagnosis.
Homocystinuria
Mice deficient in methylenetetrahydrofolate reductase exhibit hyperhomocysteinemia and decreased methylation capacity, with neuropathology and aortic lipid deposition.
Homocystinuria
Molecular and clinical characterisation of homocystinuria in two Austrian families with cystathionine beta-synthase deficiency.
Homocystinuria
Molecular characterization of five patients with homocystinuria due to severe methylenetetrahydrofolate reductase deficiency.
Homocystinuria
MTHFR: Addressing Genetic Counseling Dilemmas Using Evidence-Based Literature.
Homocystinuria
Mutational landscape screening of methylene tetrahydrofolate reductase to predict homocystinuria associated variants: An integrative computational approach.
Homocystinuria
Newborn screening for homocystinurias and methylation disorders: systematic review and proposed guidelines.
Homocystinuria
Oxidative stress and apoptosis in homocystinuria patients with genetic remethylation defects.
Homocystinuria
Pathogenicity of thermolabile methylenetetrahydrofolate reductase for vascular dementia.
Homocystinuria
Reversible leukoencephalopathy and cerebral atrophy in Homocystinuria due to MTHFR deficiency: A treatable metabolic disorder.
Homocystinuria
Sequential multiple retinal vein occlusions and transient ischemic attack in MTHFR polymorphism and protein S deficiency.
Homocystinuria
Seven novel mutations in the methylenetetrahydrofolate reductase gene and genotype/phenotype correlations in severe methylenetetrahydrofolate reductase deficiency.
Homocystinuria
Severe methylenetetrahydrofolate reductase (MTHFR) deficiency: a case report of nonclassical homocystinuria.
Homocystinuria
Severe methylenetetrahydrofolate reductase deficiency in mice results in behavioral anomalies with morphological and biochemical changes in hippocampus.
Homocystinuria
Taurine alleviates repression of betaine-homocysteine S-methyltransferase and significantly improves the efficacy of long-term betaine treatment in a mouse model of cystathionine ?-synthase-deficient homocystinuria.
Homocystinuria
The thermolabile variant 677C-->T can further reduce activity when expressed in cis with severe mutations for human methylenetetrahydrofolate reductase.
Homocystinuria
[Effect of folic acid for treatment of homocystinuria due to 5,10-methylenetetrahydrofolate reductase deficiency]
Hydatidiform Mole
667C>T and 1298A>C polymorphisms of MTHFR do not predict response to methotrexate in patients with gestational trophoblastic neoplasia.
Hydrocephalus
5,10-Methylenetetrahydrofolate reductase deficiency with progressive polyneuropathy in an infant.
Hydrocephalus
Hydrocephalus internus in two patients with 5,10-methylenetetrahydrofolate reductase deficiency.
Hydrocephalus
Multiloculated hydrocephalus of intrauterine-onset: a case report of an unexpected MTHFR A1298C positive test result.
Hyperalgesia
Investigation of MTHFR C677T Gene Polymorphism, Biochemical and Clinical Parameters in Turkish Migraine Patients: Association with Allodynia and Fatigue.
Hyperargininemia
Epidemiology of rare diseases detected by newborn screening in the Czech Republic.
Hypercholesterolemia
A comparison of the genetic and clinical risk factors for arterial hypertension between indigenous and non-indigenous people of the Shoria Mountain Region.
Hypercholesterolemia
Association of gene polymorphisms with myocardial infarction in individuals with or without conventional coronary risk factors.
Hypercholesterolemia
Genetic risk for atherothrombotic cerebral infarction in individuals stratified by sex or conventional risk factors for atherosclerosis.
Hypercholesterolemia
Individual and Joint Associations of Methylenetetrahydrofolate Reductase C677T Genotype and Plasma Homocysteine With Dyslipidemia in a Chinese Population With Hypertension.
Hypercholesterolemia
NONICHEMIC CENTRAL RETINAL VEIN OCCLUSION ASSOCIATED WITH HEREDITARY THROMBOPHYLIA.
Hypercholesterolemia
Thermolabile defect of methylenetetrahydrofolate reductase in coronary artery disease.
Hyperglycemia
MTHFR gene polymorphism is susceptible to diabetic retinopathy but not to diabetic nephropathy in Japanese type 2 diabetic patients.
Hyperglycemia
No association between MTHFR gene polymorphism and diabetic nephropathy in Japanese type II diabetic patients with proliferative diabetic retinopathy.
Hyperglycemia
Risk factors of cerebral ischemia in infants born to mothers with gestational diabetes.
Hyperglycinemia, Nonketotic
Diagnostic yield of genetic testing in epileptic encephalopathy in childhood.
Hyperhomocysteinemia
5-methyltetrahydrofolate administration is associated with prolonged survival and reduced inflammation in ESRD patients.
Hyperhomocysteinemia
A 31 year old woman with essential hypertension grade III and branch retinal vein occlusion with homozygous C677T MTHFR hyperhomocysteinemia and high Lp(a) levels.
Hyperhomocysteinemia
A case of vascular parkinsonism associated with hyperhomocysteinemia and methylenetetrahydrofolate reductase gene variant (C677T).
Hyperhomocysteinemia
A case-control study investigating the effect of MTHFR C677T variant on performance of elite athletes.
Hyperhomocysteinemia
A common mutation A1298C in human methylenetetrahydrofolate reductase gene: association with plasma total homocysteine and folate concentrations.
Hyperhomocysteinemia
A common mutation in the methylenetetrahydrofolate reductase gene (C677T) increases the risk for deep-vein thrombosis in patients with mutant factor V (factor V:Q506).
Hyperhomocysteinemia
A common mutation in the methylenetetrahydrofolate reductase gene is a determinant of hyperhomocysteinemia in epileptic patients receiving anticonvulsants.
Hyperhomocysteinemia
A novel multiplex PCR-RFLP method for simultaneous detection of the MTHFR 677 C > T, eNOS +894 G > T and - eNOS -786 T > C variants among Malaysian Malays.
Hyperhomocysteinemia
A possible synergistic effect of MTHFR C677T polymorphism on homocysteine level variations increased risk for ischemic stroke.
Hyperhomocysteinemia
A prospective cohort study of MTHFR C677T gene polymorphism and its influence on the therapeutic effect of homocysteine in stroke patients with hyperhomocysteinemia.
Hyperhomocysteinemia
A review on clotting disorders and retinal hemorrhages: Can they mimic abuse?
Hyperhomocysteinemia
A Systematic Review of Parkinson's Disease Pharmacogenomics: Is There Time for Translation into the Clinics?
Hyperhomocysteinemia
ACMG Practice Guideline: lack of evidence for MTHFR polymorphism testing.
Hyperhomocysteinemia
Acute adrenal failure associated with primary antiphospholipid syndrome and homozygosity for MTHFR C677T.
Hyperhomocysteinemia
Acute leukoencephalopathy possibly induced by phenytoin intoxication in an adult patient with methylenetetrahydrofolate reductase deficiency.
Hyperhomocysteinemia
Acute renal infarction associated with homozygous methylenetetrahydrofolate reductase mutation C677T and IgA beta-2-glycoprotein antibodies.
Hyperhomocysteinemia
Acute stroke in relation to homocysteine and methylenetetrahydrofolate reductase gene polymorphisms.
Hyperhomocysteinemia
Age and gender affect the relation between methylenetetrahydrofolate reductase C677T genotype and fasting plasma homocysteine concentrations in the Framingham Offspring Study Cohort.
Hyperhomocysteinemia
Age dependence of the influence of methylenetetrahydrofolate reductase genotype on plasma homocysteine level.
Hyperhomocysteinemia
Altered expression of methylenetetrahydrofolate reductase modifies response to methotrexate in mice.
Hyperhomocysteinemia
antiphospholipid antibodies syndrome associated with hyperhomocysteinemia related to MTHFR Gene C677T and A1298C heterozygous mutations in a young man with idiopathic hypoparathyroidism (DiGeorge syndrome).
Hyperhomocysteinemia
Association between 5,10-Methylenetetrahydrofolate Reductase C677T Gene Polymorphism and Risk of Ischemic Stroke: A Meta-analysis.
Hyperhomocysteinemia
Association between methylenetetrahydrofolate reductase (MTHFR) polymorphism and carotid intima medial thickness progression in post ischaemic stroke patient.
Hyperhomocysteinemia
Association between MTHFR 677C-T polymorphism and alcohol dependence according to Lesch and Babor typology.
Hyperhomocysteinemia
Association between thrombophilia gene polymorphisms and recurrent pregnancy loss risk in the Iranian population.
Hyperhomocysteinemia
Association of congenital cardiac defects and the C677T methylenetetrahydrofolate reductase polymorphism.
Hyperhomocysteinemia
Association of Genetic Variants with Hyperhomocysteinemia in Indian Patients with Thrombosis.
Hyperhomocysteinemia
Association of methylenetetrahydrofolate reductase (MTHFR 677C>T and 1298A>C) polymorphisms and haplotypes with silent brain infarction and homocysteine levels in a Korean population.
Hyperhomocysteinemia
Association of methylenetetrahydrofolate reductase (MTHFR) polymorphism with bone mineral density in postmenopausal Japanese women.
Hyperhomocysteinemia
Association of Methylenetetrahydrofolate Reductase C677T and Cystathionine β-Synthase Polymorphisms in Cardiovascular Disease in the Algerian Population.
Hyperhomocysteinemia
Association of Methylenetetrahydrofolate Reductase C677T Polymorphism with Hyperhomocysteinemia and Deep Vein Thrombosis in the Iranian Population.
Hyperhomocysteinemia
Association of MTHFR and RFC1 gene polymorphism with hyperhomocysteinemia and its modulation by vitamin B12 and folic acid in an Indian population.
Hyperhomocysteinemia
Association of MTRR 66A>G polymorphism with superoxide dismutase and disease activity in patients with Crohn's disease.
Hyperhomocysteinemia
Association of parental hyperhomocysteinemia and C677T Methylene tetrahydrofolate reductase (MTHFR) polymorphism with recurrent pregnancy loss.
Hyperhomocysteinemia
Association of plasma folate, plasma total homocysteine, but not methylenetetrahydrofolate reductase C667T polymorphism, with bone mineral density in postmenopausal Iranian women: a cross-sectional study.
Hyperhomocysteinemia
Association of polymorphism of methylene-tetrahydro-folate-reductase with urinary albumin excretion rate in type 1 diabetes mellitus but not with preeclampsia, retinopathy, and preterm delivery.
Hyperhomocysteinemia
Association of serum VLDL level with hyperhomocysteinemia in hypertensive patients: A cross-sectional study.
Hyperhomocysteinemia
Association of the methylene-tetrahydrofolate reductase gene rs1801133 C677T variant with serum homocysteine levels, and the severity of coronary artery disease.
Hyperhomocysteinemia
Association of Vitamin B12 Deficiency with Homozygosity of the TT MTHFR C677T Genotype, Hyperhomocysteinemia, and Endothelial Cell Dysfunction.
Hyperhomocysteinemia
Association study of methylenetetrahydrofolate reductase C677T mutation with cerebral venous thrombosis in an Iranian population.
Hyperhomocysteinemia
Association Study of MTHFR Polymorphisms with Nonarteritic Anterior Ischemic Optic Neuropathy in a Spanish Population.
Hyperhomocysteinemia
Blood S-adenosylmethionine concentrations and lymphocyte methylenetetrahydrofolate reductase activity in diabetes mellitus and diabetic nephropathy.
Hyperhomocysteinemia
C677T and A1298C polymorphisms of the methylenetetrahydrofolate reductase gene: incidence and effect of combined genotypes on plasma fasting and post-methionine load homocysteine in vascular disease.
Hyperhomocysteinemia
C677T methylenetetrahydrofolate reductase and plasma homocysteine levels among Thai vegans and omnivores.
Hyperhomocysteinemia
C677T methylenetetrahydrofolate reductase gene polymorphism as a risk factor involved in venous thromboembolism: a population-based case-control study.
Hyperhomocysteinemia
C677T MTHFR Gene Polymorphism is Contributing Factor in Development of Renal Impairment in Young Hypertensive Patients.
Hyperhomocysteinemia
C677T mutation of methylenetetrahydrofolate reductase gene and serum homocysteine levels in Turkish patients with coronary artery disease.
Hyperhomocysteinemia
C677T mutation of the methylenetetrahydrofolate reductase gene among the Korean infants in Seoul city.
Hyperhomocysteinemia
C677T variant in the methylentetrahydrofolate reductase gene is a genetic risk factor for primary open-angle glaucoma.
Hyperhomocysteinemia
Case-control Study of methylenetetrahydrofolate reductase mutations and hyperhomocysteinemia and risk of stroke.
Hyperhomocysteinemia
CBS mutations and MTFHR SNPs causative of hyperhomocysteinemia in Pakistani children.
Hyperhomocysteinemia
Cerebral Venous Thrombosis and Livedo Reticularis in a Case with MTHFR 677TT Homozygote.
Hyperhomocysteinemia
Cerebral Venous Thrombosis with Subarachnoid Hemorrhage: A Case Report.
Hyperhomocysteinemia
Characterization of mutations in severe methylenetetrahydrofolate reductase deficiency reveals an FAD-responsive mutation.
Hyperhomocysteinemia
Children with stroke: polymorphism of the MTHFR gene, mild hyperhomocysteinemia, and vitamin status.
Hyperhomocysteinemia
Clinical Impact of Thrombophilia Screening in Young Adults with Ischemic Stroke.
Hyperhomocysteinemia
Clinical utility of folate pathway genetic polymorphisms in the diagnosis of autism spectrum disorders.
Hyperhomocysteinemia
Clinical utility of genotyping the 677C>T variant of methylenetetrahydrofolate reductase in humans is decreased in the post-folic acid fortification era.
Hyperhomocysteinemia
Coenzyme Q10, Hyperhomocysteinemia and MTHFR C677T Polymorphism in Levodopa-treated Parkinson's Disease Patients.
Hyperhomocysteinemia
Coexistence of Neurofibromatosis Type-1 and MTHFR C677T Gene Mutation in a Young Stroke Patient: A Case Report.
Hyperhomocysteinemia
Combination of angiotensin-converting enzyme and methylenetetrahydrofolate reductase gene polymorphisms as determinant risk factors for chronic allograft dysfunction.
Hyperhomocysteinemia
Common C677T polymorphism of the methylenetetrahydrofolate reductase gene and the risk of venous thromboembolism: meta-analysis of 31 studies.
Hyperhomocysteinemia
Common methylenetetrahydrofolate reductase gene mutation leads to hyperhomocysteinemia but not to vascular disease: the result of a meta-analysis.
Hyperhomocysteinemia
Common mutation in the methylenetetrahydrofolate reductase gene offers no support for mild hyperhomocysteinemia being a causal risk factor for cardiovascular disease.
Hyperhomocysteinemia
Common polymorphisms in methylenetetrahydrofolate reductase (MTHFR): relationships with plasma homocysteine concentrations and cognitive status in elderly northern italian subjects.
Hyperhomocysteinemia
Compound heterozygosity for the C677T and A1298C mutations of the MTHFR gene in a case of hyperhomocysteinemia with recurrent deep thrombosis at young age.
Hyperhomocysteinemia
Congenital MTHFR deficiency causing early-onset cerebral stroke in a case homozygous for MTHFR thermolabile variant.
Hyperhomocysteinemia
Contribution of the cystathionine beta-synthase gene (844ins68) polymorphism to the risk of early-onset venous and arterial occlusive disease and of fasting hyperhomocysteinemia.
Hyperhomocysteinemia
Correlation between C677T MTHFR gene polymorphism, plasma homocysteine levels and the incidence of CAD.
Hyperhomocysteinemia
Correlation of a common mutation in the methylenetetrahydrofolate reductase gene with plasma homocysteine in patients with premature coronary artery disease.
Hyperhomocysteinemia
Correlation of the C677T MTHFR genotype with homocysteine levels in children with sickle cell disease.
Hyperhomocysteinemia
Cystathionine ?-synthase and methylenetetrahydrofolate reductase mutations in Mexican individuals with hyperhomocysteinemia.
Hyperhomocysteinemia
Differences in the frequency of the C677T mutation in the methylenetetrahydrofolate reductase (MTHFR) gene among the Lebanese population.
Hyperhomocysteinemia
Differential contribution of MTHFR C677T variant to the risk of diabetic nephropathy in Lebanese and Bahraini Arabs.
Hyperhomocysteinemia
Disturbed One-Carbon Metabolism Causing Adverse Reproductive Outcomes in Mice Is Associated with Altered Expression of Apolipoprotein AI and Inflammatory Mediators PPAR?, Interferon-?, and Interleukin-10.
Hyperhomocysteinemia
DNA methylation status of the methylenetetrahydrofolate reductase gene promoter in peripheral blood of end-stage renal disease patients.
Hyperhomocysteinemia
Early Thrombosis of a Mitral Annuloplasty Ring in a Patient with MTHFR and Factor V Leiden Mutations.
Hyperhomocysteinemia
Effect of methylenetetrahydrofolate reductase 677C-->T polymorphism on toxicity and homocysteine plasma level after chronic methotrexate treatment of ovarian cancer patients.
Hyperhomocysteinemia
Effect of Mthfr genotype on diet-induced hyperhomocysteinemia and vascular function in mice.
Hyperhomocysteinemia
Effect of MTHFR genotypes and hyperhomocysteinemia on patient and graft survival in kidney transplant recipients.
Hyperhomocysteinemia
Effect of MTHFR polymorphisms on hyperhomocysteinemia in levodopa-treated Parkinsonian patients.
Hyperhomocysteinemia
Effect of Vitamin B(12) and Folate on Homocysteine levels in colorectal cancer.
Hyperhomocysteinemia
Effects of MTHFR C677T polymorphism on vitamin D, homocysteine and natural killer cell cytotoxicity in women with recurrent pregnancy losses.
Hyperhomocysteinemia
Effects of MTHFR gene polymorphism on the clinical and electrophysiological characteristics of migraine.
Hyperhomocysteinemia
Effects of Periconceptional Multivitamin Supplementation on Folate and Homocysteine Levels Depending on Genetic Variants of Methyltetrahydrofolate Reductase in Infertile Japanese Women.
Hyperhomocysteinemia
Effects of polymorphisms of methionine synthase and methionine synthase reductase on total plasma homocysteine in the NHLBI Family Heart Study.
Hyperhomocysteinemia
Efficacy of Folic Acid in Children With Migraine, Hyperhomocysteinemia and MTHFR Polymorphisms.
Hyperhomocysteinemia
Elevated homocysteine reduces apolipoprotein A-I expression in hyperhomocysteinemic mice and in males with coronary artery disease.
Hyperhomocysteinemia
Evaluation of the relationship between C677T variants of methylenetetrahydrofolate reductase gene and hyperhomocysteinemia in children receiving antiepileptic drug therapy.
Hyperhomocysteinemia
Factor V G1691A, apo E4 allele, hyperhomocysteinemia and MTHFR C677T in a young patient with myocardial infarction.
Hyperhomocysteinemia
Factor V G1691A, prothrombin G20210A, and methylenetetrahydrofolate reductase [MTHFR] C677T gene polymorphism in angiographically documented coronary artery disease.
Hyperhomocysteinemia
Factor V Leiden, prothrombin 20210A, methylenetetrahydrofolate reductase 677T, and population genetics.
Hyperhomocysteinemia
Factor V Leiden, prothrombin 20210G>A, MTHFR 677C>T and 1298A>C, and homocysteinemia in Tunisian blood donors.
Hyperhomocysteinemia
Fasting plasma homocysteine levels are increased in young patients with acute myocardial infarction from Western India.
Hyperhomocysteinemia
Folate Deficiency and Gene Polymorphisms of MTHFR, MTR and MTRR Elevate the Hyperhomocysteinemia Risk.
Hyperhomocysteinemia
Folate status and a new repletion cut-off value in a group of healthy Majorcan women.
Hyperhomocysteinemia
Folate, homocysteine levels, methylenetetrahydrofolate reductase (MTHFR) 677C --> T variant, and the risk of myocardial infarction in young women: effect of female hormones on homocysteine levels.
Hyperhomocysteinemia
Folate, vitamin B12, homocysteine, and the MTHFR 677C->T polymorphism in anxiety and depression: the Hordaland Homocysteine Study.
Hyperhomocysteinemia
Frequency of methylenetetrahydrofolate reductase C677T polymorphism in patients with cardiovascular disease in Eastern Saudi Arabia.
Hyperhomocysteinemia
Frequency of the 677 C-->T mutation of the methylenetetrahydrofolate reductase gene among Kuwaiti sickle cell disease patients.
Hyperhomocysteinemia
Functional characterization of missense mutations in severe methylenetetrahydrofolate reductase deficiency using a human expression system.
Hyperhomocysteinemia
Further evidence that hyperhomocysteinemia and methylenetetrahydrofolate reductase C677T and A1289C polymorphisms are not risk factors for schizophrenia.
Hyperhomocysteinemia
G1793A polymorphisms in the methylene-tetrahydrofolate gene: effect of folic acid on homocysteine levels.
Hyperhomocysteinemia
Genetic and environmental influences on total plasma homocysteine and coronary artery disease (CAD) risk among South Indians.
Hyperhomocysteinemia
Genetic and nongenetic factors influencing plasma homocysteine levels in patients with ischemic cerebrovascular disease and in healthy control subjects.
Hyperhomocysteinemia
Genetic causes of mild hyperhomocysteinemia in patients with premature occlusive coronary artery diseases.
Hyperhomocysteinemia
Genetic determinants of fasting and post-methionine hyperhomocysteinemia in patients with retinal vein occlusion.
Hyperhomocysteinemia
Genetic effect of MTHFR C677T polymorphism on the structural covariance network and white-matter integrity in Alzheimer's disease.
Hyperhomocysteinemia
Genetic or nutritional disorders in homocysteine or folate metabolism increase protein N-homocysteinylation in mice.
Hyperhomocysteinemia
Genetic polymorphism of 5,10-MTHFR reductase gene in offspring of patients with myocardial infarction.
Hyperhomocysteinemia
Genetic polymorphism of methylenetetrahydrofolate reductase G1793A, hyperhomocysteinemia, and folate deficiency correlate with ulcerative colitis in central China.
Hyperhomocysteinemia
Genetic polymorphisms of methylenetetrahydrofolate reductase (MTHFR) and methionine synthase reductase (MTRR) in ethnic populations in Texas; a report of a novel MTHFR polymorphic site, G1793A.
Hyperhomocysteinemia
Genetic predisposition to hyperhomocysteinemia: deficiency of methylenetetrahydrofolate reductase (MTHFR).
Hyperhomocysteinemia
Genetic profile and determinants of homocysteine levels in Kazakhstan patients with breast cancer.
Hyperhomocysteinemia
Genetic variants in the MTHFR are not associated with fatty liver disease.
Hyperhomocysteinemia
Genetic variations observed in arterial and venous thromboembolism--relevance for therapy, risk prevention and prognosis.
Hyperhomocysteinemia
Genetic variations of MTHFR gene and their association with preterm birth in Korean women.
Hyperhomocysteinemia
Genetic, dietary, and other lifestyle determinants of serum homocysteine levels in young adults in Costa Rica.
Hyperhomocysteinemia
Genotype and allele frequencies of the polymorphic methylenetetrahydrofolate reductase gene in Turkey.
Hyperhomocysteinemia
Genotype and haplotype distributions of MTHFR677C>T and 1298A>C single nucleotide polymorphisms: a meta-analysis.
Hyperhomocysteinemia
Glycine and L-arginine treatment causes hyperhomocysteinemia in cerebral creatine transporter deficiency patients.
Hyperhomocysteinemia
Haplotypes of the MTHFR gene are associated with an increased risk of breast cancer in a Han Chinese population in Gansu province.
Hyperhomocysteinemia
Has enhanced folate status during pregnancy altered natural selection and possibly Autism prevalence? A closer look at a possible link.
Hyperhomocysteinemia
Heterozygous methylenetetrahydrofolate reductase 677C-T gene mutation with mild hyperhomocysteinemia associated with intrauterine iliofemoral artery thrombosis.
Hyperhomocysteinemia
Heterozygous prothrombin 20210G/A mutation, associated with hyperhomocysteinemia, and homozygous methylenetetrahydrofolate reductase 677C/T mutation, in a patient with portal and mesenteric venous thrombosis.
Hyperhomocysteinemia
High prevalence of hyperhomocysteinemia in chronic alcoholism: the importance of the thermolabile form of the enzyme methylenetetrahydrofolate reductase (MTHFR).
Hyperhomocysteinemia
High prevalence of hyperhomocysteinemia related to folate deficiency and the 677C-->T mutation of the gene encoding methylenetetrahydrofolate reductase in coastal West Africa.
Hyperhomocysteinemia
Homocysteine and cardiovascular disease: interactions between nutrition, genetics and lifestyle.
Hyperhomocysteinemia
Homocysteine and carotid intima-media thickness: a critical appraisal of the evidence.
Hyperhomocysteinemia
Homocysteine and methylenetetrahydrofolate reductase in subjects undergoing coronary angiography.
Hyperhomocysteinemia
Homocysteine and MTHFR and VEGF gene polymorphisms: impact on coronary artery disease.
Hyperhomocysteinemia
Homocysteine and the MTHFR 677C-->T allele in premature coronary artery disease. Case control and family studies.
Hyperhomocysteinemia
Homocysteine excess: delineating the possible mechanism of neurotoxicity and depression.
Hyperhomocysteinemia
Homocysteine levels and disease duration independently correlate with coronary artery calcification in patients with systemic lupus erythematosus.
Hyperhomocysteinemia
Homocysteine levels and MTHFR polymorphisms in young patients with acute myocardial infarction: a case control study.
Hyperhomocysteinemia
Homocysteine levels are associated with MTHFR A1298C polymorphism in Indian population.
Hyperhomocysteinemia
Homocysteine Levels in Chronic Gastritis and Other Conditions: Relations to Incident Cardiovascular Disease and Dementia.
Hyperhomocysteinemia
Homocysteine modulates the effect of simvastatin on expression of ApoA-I and NF-kappaB/iNOS.
Hyperhomocysteinemia
Homocysteine serum levels and MTHFR C677T genotype in patients with Parkinson's disease, with and without levodopa therapy.
Hyperhomocysteinemia
Homocysteine synthesis is elevated but total remethylation is unchanged by the methylenetetrahydrofolate reductase 677C->T polymorphism and by dietary folate restriction in young women.
Hyperhomocysteinemia
Homocysteine, endothelial dysfunction, and coronary artery disease: emerging strategy for secondary prevention.
Hyperhomocysteinemia
Homocysteine, methylenetetrahydrofolate reductase C677T polymorphism and the B-vitamins: a facet of nature-nurture interplay.
Hyperhomocysteinemia
Homocysteine, pharmacogenetics, and neurotoxicity in children with leukemia.
Hyperhomocysteinemia
Homocysteine, small-vessel disease, and atherosclerosis: an MRI study of 825 stroke patients.
Hyperhomocysteinemia
Homocysteine, vitamin B status and MTHFR polymorphisms in Italian infertile women.
Hyperhomocysteinemia
Homocysteine-betaine interactions in a murine model of 5,10-methylenetetrahydrofolate reductase deficiency.
Hyperhomocysteinemia
Homocysteinemia is inversely correlated with platelet count and directly correlated with sE- and sP-selectin levels in females homozygous for C677T methylenetetrahydrofolate reductase.
Hyperhomocysteinemia
Homozygous C677T mutation in the MTHFR gene as an independent risk factor for multiple small-artery occlusions.
Hyperhomocysteinemia
Homozygous C677T mutation of the 5,10 methylenetetrahydrofolate reductase gene and hyperhomocysteinemia in Italian patients with a history of early-onset ischemic stroke.
Hyperhomocysteinemia
Homozygous VN (677C to T) and d/D (2756G to A) variants in the methylenetetrahydrofolate and methionine synthase genes in a case of hyperhomocysteinemia with stroke at young age.
Hyperhomocysteinemia
Hydrogen sulphide pathway contributes to the enhanced human platelet aggregation in hyperhomocysteinemia.
Hyperhomocysteinemia
Hyperbaric oxygen therapy in branch retinal artery occlusion in a 15-year-old boy with methylenetetrahydrofolate reductase mutation.
Hyperhomocysteinemia
Hypercoagulable state and methylenetetrahydrofolate reductase (MTHFR) C677T mutation in patients with beta-thalassemia major in Kuwait.
Hyperhomocysteinemia
Hypercoagulable thrombophilic defects and hyperhomocysteinemia in patients with recurrent pregnancy loss.
Hyperhomocysteinemia
Hyperhomocysteinemia and C677T MTHFR Genotype in Patients With Retinal Vein Thrombosis.
Hyperhomocysteinemia
Hyperhomocysteinemia and homozygous MTHFR 677C>T mutation finding in an Alzheimer's disease case with metabolic syndrome diagnosis.
Hyperhomocysteinemia
HYPERHOMOCYSTEINEMIA AND ITS TREATMENT IN PATIENTS WITH PARKINSON'S DISEASE.
Hyperhomocysteinemia
Hyperhomocysteinemia and methylenetetrahydrofolate reductase 677C-->T and 1298A-->C mutations in patients with inflammatory bowel disease.
Hyperhomocysteinemia
Hyperhomocysteinemia and Methylenetetrahydrofolate Reductase C677T Polymorphism in Cerebral Veno-sinus Thrombosis.
Hyperhomocysteinemia
Hyperhomocysteinemia and methylenetetrahydrofolate reductase polymorphism in a patient with coronary artery disease and repetitive miscarriages.
Hyperhomocysteinemia
Hyperhomocysteinemia and methylenetetrahydrofolate reductase polymorphism in cervical artery dissection: a meta-analysis.
Hyperhomocysteinemia
Hyperhomocysteinemia and methylenetetrahydrofolate reductase polymorphism in patients with Parkinson's disease.
Hyperhomocysteinemia
Hyperhomocysteinemia and MTHFR C677T and A1298C polymorphisms are associated with chronic allograft nephropathy in renal transplant recipients.
Hyperhomocysteinemia
Hyperhomocysteinemia and MTHFR C677T homozygosity in a vegetarian male with sinovenous thrombosis of the brain.
Hyperhomocysteinemia
Hyperhomocysteinemia and MTHFR C677T polymorphism in patients with portal vein thrombosis complicating liver cirrhosis.
Hyperhomocysteinemia
Hyperhomocysteinemia and MTHFR polymorphisms as antenatal risk factors of white matter abnormalities in two cohorts of late preterm and full term newborns.
Hyperhomocysteinemia
Hyperhomocysteinemia and MTHFR polymorphisms in association with orofacial clefts and congenital heart defects: a meta-analysis.
Hyperhomocysteinemia
Hyperhomocysteinemia and of Methylenetetrahydrofolate Reductase (C677T) Genetic Polymorphism in Patients with Deep Vein Thrombosis.
Hyperhomocysteinemia
Hyperhomocysteinemia and polymorphisms of the methylenetetrahydrofolate gene in hemodialysis and peritoneal dialysis patients.
Hyperhomocysteinemia
Hyperhomocysteinemia and prevalence of polymorphisms of homocysteine metabolism-related enzymes in patients with inflammatory bowel disease.
Hyperhomocysteinemia
Hyperhomocysteinemia and the compound heterozygous state for methylene tetrahydrofolate reductase are independent risk factors for deep vein thrombosis among South Indians.
Hyperhomocysteinemia
Hyperhomocysteinemia and the methylenetetrahydrofolate reductase 677C-T mutation in patients under 50 years of age affected by central retinal vein occlusion.
Hyperhomocysteinemia
Hyperhomocysteinemia and the MTHFR C677T mutation in Budd-Chiari syndrome.
Hyperhomocysteinemia
Hyperhomocysteinemia and the MTHFR C677T mutation in central retinal vein occlusion.
Hyperhomocysteinemia
Hyperhomocysteinemia and the MTHFR C677T polymorphism promote steatosis and fibrosis in chronic hepatitis C patients.
Hyperhomocysteinemia
Hyperhomocysteinemia as an independent risk factor for silent brain infarction.
Hyperhomocysteinemia
Hyperhomocysteinemia but not MTHFR genotype is associated with young-onset essential hypertension.
Hyperhomocysteinemia
Hyperhomocysteinemia but not the C677T mutation of methylenetetrahydrofolate reductase is an independent risk determinant of carotid wall thickening. The Perth Carotid Ultrasound Disease Assessment Study (CUDAS)
Hyperhomocysteinemia
Hyperhomocysteinemia in central retinal vein occlusion in young adults.
Hyperhomocysteinemia
Hyperhomocysteinemia in high-aged subjects: relation of B-vitamins, folic acid, renal function and the methylenetetrahydrofolate reductase mutation.
Hyperhomocysteinemia
Hyperhomocysteinemia in men with a reproductive history of fetal neural tube defects: Three case reports and literature review.
Hyperhomocysteinemia
Hyperhomocysteinemia increases the risk of venous thrombosis independent of the C677T mutation of the methylenetetrahydrofolate reductase gene in selected Brazilian patients.
Hyperhomocysteinemia
Hyperhomocysteinemia is a risk factor of recurrent coronary event in young patients irrespective to the MTHFR C677T polymorphism.
Hyperhomocysteinemia
Hyperhomocysteinemia is associated with hypertriglyceridemia in mice with methylenetetrahydrofolate reductase deficiency.
Hyperhomocysteinemia
Hyperhomocysteinemia is Associated with Inflammation, Bone Resorption, Vitamin B12 and Folate Deficiency and MTHFR C677T Polymorphism in Postmenopausal Women with Decreased Bone Mineral Density.
Hyperhomocysteinemia
Hyperhomocysteinemia, antithrombin consumption, and early venous graft closure in surgical coronary revascularization.
Hyperhomocysteinemia
Hyperhomocysteinemia, C677T MTHFR polymorphism and ischemic stroke in Tunisian patients.
Hyperhomocysteinemia
Hyperhomocysteinemia, deep vein thrombosis and vitamin B12 deficiency in a metformin-treated diabetic patient.
Hyperhomocysteinemia
Hyperhomocysteinemia, intima-media thickness and C677T MTHFR gene polymorphism: A correlation study in patients with cognitive impairment.
Hyperhomocysteinemia
Hyperhomocysteinemia, low folate and vitamin B12 concentrations, and methylene tetrahydrofolate reductase mutation in cerebral venous thrombosis.
Hyperhomocysteinemia
Hyperhomocysteinemia, low folate status, homozygous C677T mutation of the methylene tetrahydrofolate reductase and renal arterial thrombosis.
Hyperhomocysteinemia
Hyperhomocysteinemia, methylenetetrahydrofolate reductase 677TT genotype, and the risk for schizophrenia: a Dutch population based case-control study.
Hyperhomocysteinemia
Hyperhomocysteinemia, methylenetetrahydrofolate reductase c.677C>T polymorphism, and risk of cancer: cross-sectional and prospective studies and meta-analyses of 75,000 cases and 93,000 controls.
Hyperhomocysteinemia
Hyperhomocysteinemia, MTHFR C677T genotype and low folate levels: a risk combination for acute coronary disease in a Portuguese population.
Hyperhomocysteinemia
Hyperhomocysteinemia: clinical and therapeutical involvement in venous thrombosis.
Hyperhomocysteinemia
Hypertrophy of IMC of carotid artery in Parkinson's disease is associated with L-DOPA, homocysteine, and MTHFR genotype.
Hyperhomocysteinemia
Impact of Genetic Polymorphism of methylenetetrahydrofolate reductase C677T on Development of Hyperhomocysteinemia and Related Oxidative Changes in Egyptian ?-Thalassemia Major Patients.
Hyperhomocysteinemia
Impact of MTHFR (C677T) gene polymorphism on antiepileptic drug monotherapy in North Indian epileptic population.
Hyperhomocysteinemia
Increased Factor V Leiden frequency is associated with venous thrombotic events among young Brazilian patients.
Hyperhomocysteinemia
Influence of 5,10-methylenetetrahydrofolate reductase gene polymorphism on plasma homocysteine concentration in patients with end-stage renal disease.
Hyperhomocysteinemia
Influence of combined methylenetetrahydrofolate reductase (MTHFR) and thymidylate synthase enhancer region (TSER) polymorphisms to plasma homocysteine levels in Korean patients with recurrent spontaneous abortion.
Hyperhomocysteinemia
Inherited and Acquired Thrombophilia in Adults with Retinal Vascular Occlusion: A Systematic Review and Meta-Analysis.
Hyperhomocysteinemia
Inherited thrombophilias in pregnant patients: detection and treatment paradigm.
Hyperhomocysteinemia
Insufficient S-sulfhydration of Methylenetetrahydrofolate Reductase Contribute to the Progress of Hyperhomocysteinemia.
Hyperhomocysteinemia
Interaction between hyperhomocysteinemia and inherited thrombophilic factors in venous thromboembolism.
Hyperhomocysteinemia
Interactions of Methylenetetrahydrofolate Reductase Gene Polymorphisms, Folate, and Homocysteine on Blood Pressure in a Chinese Hypertensive Population.
Hyperhomocysteinemia
Intermediate and severe hyperhomocysteinemia with thrombosis: a study of genetic determinants.
Hyperhomocysteinemia
Intermediate hyperhomocysteinemia resulting from compound heterozygosity of methylenetetrahydrofolate reductase mutations.
Hyperhomocysteinemia
Interplay between methylenetetrahydrofolate reductase gene polymorphism 677C-->T and serum folate levels in determining hyperhomocysteinemia in heart transplant recipients.
Hyperhomocysteinemia
Investigation of methylenetetrahydrofolate reductase C677T and factor V Leiden mutation as a genetic marker for retinal vein occlusion.
Hyperhomocysteinemia
Investigation of MTHFR gene C677T polymorphism in cardiac syndrome X patients.
Hyperhomocysteinemia
Is hyperhomocysteinemia a causal factor for heart failure? The impact of the functional variants of MTHFR and PON1 on ischemic and non-ischemic etiology.
Hyperhomocysteinemia
Is there an association between the development of metabolic syndrome in PCOS patients and the C677T MTHFR gene polymorphism?
Hyperhomocysteinemia
Ischemic stroke subtypes and thrombophilia in young and elderly Brazilian stroke patients admitted to a rehabilitation hospital.
Hyperhomocysteinemia
Lack of association between genetic polymorphisms in enzymes associated with folate metabolism and unexplained reduced sperm counts.
Hyperhomocysteinemia
Lack of association of methylenetetrahydrofolate reductase 677C>T mutation with coronary artery disease in a Pakistani population.
Hyperhomocysteinemia
Life-threatening methylenetetrahydrofolate reductase (MTHFR) deficiency with extremely early onset: Characterization of two novel mutations in compound heterozygous patients.
Hyperhomocysteinemia
Livedoid vasculopathy and hypercoagulability in a patient with primary Sjögren's syndrome.
Hyperhomocysteinemia
Livedoid vasculopathy associated with combined prothrombin G20210A and factor V (Leiden) heterozygosity and MTHFR C677T homozygosity.
Hyperhomocysteinemia
Low frequency of mutated methylenetetrahydrofolate reductase 677C-->T and 1298A-->C genetics single nucleotide polymorphisms (SNPs) in Sub-Saharan populations.
Hyperhomocysteinemia
Manifestations of neurological symptoms and thromboembolism in adults with MTHFR-deficiency.
Hyperhomocysteinemia
Maternal cerebral venous thrombosis, uncommon but serious disorder, pathologic predictors and contribution of prothrombotic abnormalities.
Hyperhomocysteinemia
Medical cost savings in Sakado City and worldwide achieved by preventing disease by folic acid fortification.
Hyperhomocysteinemia
MEK Inhibitor-Associated Central Retinal Vein Occlusion Associated with Hyperhomocysteinemia and MTHFR Variants.
Hyperhomocysteinemia
Mesenteric venous thrombosis with bowel infarction and hyperhomocysteinemia due to homozygous methylenetetrahydrofolate reductase C677T genotype.
Hyperhomocysteinemia
Meta-Prediction of MTHFR Gene Polymorphism Mutations and Associated Risk for Colorectal Cancer.
Hyperhomocysteinemia
Metabolic syndrome and insulin resistance in schizophrenia patients receiving antipsychotics genotyped for the methylenetetrahydrofolate reductase (MTHFR) 677C/T and 1298A/C variants.
Hyperhomocysteinemia
Methylenetetrahydrofolate reductase (C677T and A1298C) polymorphisms, hyperhomocysteinemia, and ischemic stroke in Tunisian patients.
Hyperhomocysteinemia
Methylenetetrahydrofolate reductase (MTHFR) 677C>T and methionine synthase reductase (MTRR) 66A>G polymorphisms: association with serum homocysteine and angiographic coronary artery disease in the era of flour products fortified with folic acid.
Hyperhomocysteinemia
Methylenetetrahydrofolate Reductase (MTHFR) C677T polymorphism and high plasma homocysteine in Chronic Hepatitis C (CHC) infected patients from the Northeast of Brazil.
Hyperhomocysteinemia
Methylenetetrahydrofolate reductase 677 C-->T mutation and coronary heart disease risk in UK Indian Asians.
Hyperhomocysteinemia
Methylenetetrahydrofolate reductase C677T and A1298C polymorphism and changes in homocysteine concentrations in women with idiopathic recurrent pregnancy losses.
Hyperhomocysteinemia
Methylenetetrahydrofolate reductase C677T gene mutation and hyperhomocysteinemia in Budd-Chiari syndrome and portal vein thrombosis: A systematic review and meta-analysis of observational studies.
Hyperhomocysteinemia
Methylenetetrahydrofolate reductase C677T genotype and venous thromboembolic disease.
Hyperhomocysteinemia
Methylenetetrahydrofolate reductase C677T mutation and risk of retinal vein thrombosis.
Hyperhomocysteinemia
Methylenetetrahydrofolate reductase C677T polymorphism, hypertension and risk of stroke: a prospective, nested case-control study.
Hyperhomocysteinemia
Methylenetetrahydrofolate reductase C677T variant and hyperhomocysteinemia in subarachnoid hemorrhage patients from India.
Hyperhomocysteinemia
Methylenetetrahydrofolate Reductase Gene C677T Polymorphism-Dietary Pattern Interaction on Hyperhomocysteinemia in a Chinese Population: A Cross-Sectional Study.
Hyperhomocysteinemia
Methylenetetrahydrofolate reductase gene mutation and hyperhomocysteinemia as a risk factor for coronary heart disease in the Indian population.
Hyperhomocysteinemia
Methylenetetrahydrofolate reductase gene polymorphism and childhood stroke.
Hyperhomocysteinemia
Methylenetetrahydrofolate Reductase Gene Polymorphism and Serum Homocysteine Levels in Nonalcoholic Fatty Liver Disease.
Hyperhomocysteinemia
Methylenetetrahydrofolate reductase gene polymorphism, homocysteine and risk of macroangiopathy in Type 2 diabetes mellitus.
Hyperhomocysteinemia
Methylenetetrahydrofolate reductase gene polymorphism, hyperhomocysteinemia and occlusive retinal vascular disease in type 2 diabetic and non-diabetic subjects.
Hyperhomocysteinemia
Methylenetetrahydrofolate reductase gene polymorphism, hyperhomocysteinemia, and cardiovascular diseases in chronic hemodialysis patients.
Hyperhomocysteinemia
Methylenetetrahydrofolate reductase gene polymorphisms in 13 Chinese ethnic populations.
Hyperhomocysteinemia
Methylenetetrahydrofolate reductase gene polymorphisms in patients with nonalcoholic steatohepatitis (NASH).
Hyperhomocysteinemia
Methylenetetrahydrofolate Reductase Gene-specific Methylation and Recurrent Miscarriages: A Case- Control Study from North India.
Hyperhomocysteinemia
Methylenetetrahydrofolate reductase genetic polymorphisms in patients with cataract.
Hyperhomocysteinemia
Methylenetetrahydrofolate reductase genetic polymorphisms in patients with primary open-angle glaucoma.
Hyperhomocysteinemia
Methylenetetrahydrofolate reductase genotypes and early-onset coronary artery disease.
Hyperhomocysteinemia
Methylenetetrahydrofolate reductase polymorphism (C677T), hyperhomocysteinemia, and risk of ischemic cardiovascular disease and venous thromboembolism: prospective and case-control studies from the Copenhagen City Heart Study.
Hyperhomocysteinemia
Methylenetetrahydrofolate Reductase Polymorphisms and Risk of Recurrent Pregnancy Loss: a Case-Control Study.
Hyperhomocysteinemia
Methylenetetrahydrofolate reductase TT genotype as a predictor of cardiovascular risk in hypertensive adolescents.
Hyperhomocysteinemia
Methyltetrahydrofolate reductase C677T gene mutation and hyperhomocysteinemia as a novel risk factor for diabetic nephropathy.
Hyperhomocysteinemia
Mice deficient in methylenetetrahydrofolate reductase exhibit hyperhomocysteinemia and decreased methylation capacity, with neuropathology and aortic lipid deposition.
Hyperhomocysteinemia
Microarray analysis of brain RNA in mice with methylenetetrahydrofolate reductase deficiency and hyperhomocysteinemia.
Hyperhomocysteinemia
Mild hyperhomocysteinemia and MTHFR C677T do not increase the risk for venous thrombosis in a Spanish population.
Hyperhomocysteinemia
Mild hyperhomocysteinemia and the common C677T polymorphism of methylene tetrahydrofolate reductase gene are not associated with the metabolic syndrome in Type 2 diabetes.
Hyperhomocysteinemia
Mild hyperhomocysteinemia, C677T polymorphism on methylenetetrahydrofolate reductase gene and the risk of macroangiopathy in type 2 diabetes: a prospective study.
Hyperhomocysteinemia
Molecular genetic analysis in mild hyperhomocysteinemia: a common mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for cardiovascular disease.
Hyperhomocysteinemia
Morton's foot and pyridoxal 5'-phosphate deficiency: genetically linked traits.
Hyperhomocysteinemia
MR and proton MR spectroscopy of the brain in hyperhomocysteinemia caused by methylenetetrahydrofolate reductase deficiency.
Hyperhomocysteinemia
MTHFR A1298C and C677T Polymorphisms Are Associated with Increased Risk of Venous Thromboembolism: A Retrospective Chart Review Study.
Hyperhomocysteinemia
MTHFR A1298C polymorphisms reduce the risk of congenital heart defects: a meta-analysis from 16 case-control studies.
Hyperhomocysteinemia
MTHFR C677T and A1298C gene polymorphisms and hyperhomocysteinemia as risk factors of diabetic nephropathy in type 2 diabetes patients.
Hyperhomocysteinemia
MTHFR C677T mutation in central retinal vein occlusion: a case-control study in Chinese population.
Hyperhomocysteinemia
MTHFR C677T polymorphism is associated with hyperlipidemia in women with polycystic ovary syndrome.
Hyperhomocysteinemia
MTHFR C677T polymorphism, folate, vitamin B12 and homocysteine in recurrent pregnancy losses: a case control study among north Indian women.
Hyperhomocysteinemia
MTHFR C677T polymorphism, folic acid and hyperhomocysteinemia in levodopa treated patients with Parkinson's disease.
Hyperhomocysteinemia
MTHFR C677T predisposes to POAG but not to PACG in a North Indian population: a case control study.
Hyperhomocysteinemia
MTHFR C677T, MTHFR A1298C, and OPG A163G polymorphisms in Mexican patients with rheumatoid arthritis and osteoporosis.
Hyperhomocysteinemia
MTHFR Gene Polymorphisms and Cardiovascular Risk Factors, Clinical-Imagistic Features and Outcome in Cerebral Venous Sinus Thrombosis.
Hyperhomocysteinemia
MTHFR homozygous mutation and additional risk factors for cerebral infarction in a large Italian family.
Hyperhomocysteinemia
MTHFR polymorphism and risk of periprocedural myocardial infarction after coronary stenting.
Hyperhomocysteinemia
MTHFR: Addressing Genetic Counseling Dilemmas Using Evidence-Based Literature.
Hyperhomocysteinemia
Multidisciplinary approach and anesthetic management of a surgical cancer patient with methylene tetrahydrofolate reductase deficiency: a case report and review of the literature.
Hyperhomocysteinemia
Multifactorial Painful Leg Ulcers Due to Hyperhomocysteinemia, Plasminogen Activator Inhibitor-1 4G/5G Heterozygote Gene Mutation, and Beta Thalassemia Minor: A Case Report.
Hyperhomocysteinemia
Mutation (677 C to T) in the methylenetetrahydrofolate reductase gene aggravates hyperhomocysteinemia in hemodialysis patients.
Hyperhomocysteinemia
Mutation A1298C of methylenetetrahydrofolate reductase: risk for early coronary disease not associated with hyperhomocysteinemia.
Hyperhomocysteinemia
Mutation Update and Review of Severe Methylenetetrahydrofolate Reductase Deficiency.
Hyperhomocysteinemia
Mutations in methylenetetrahydrofolate reductase or cystathionine beta-synthase gene, or a high-methionine diet, increase homocysteine thiolactone levels in humans and mice.
Hyperhomocysteinemia
Mutations in MTHFR and POLG impaired activity of the mitochondrial respiratory chain in 46-year-old twins with spastic paraparesis.
Hyperhomocysteinemia
Mutations in the gene for methylenetetrahydrofolate reductase, homocysteine levels, and vitamin status in women with a history of preeclampsia.
Hyperhomocysteinemia
Mutations of the MTHFR gene (428C>T and [458G>T+459C>T]) markedly decrease MTHFR enzyme activity.
Hyperhomocysteinemia
Myocardial infarction and venous thrombosis in a 42-year old woman with heterozygous methylenetetrahydrofolate reductase (MTHRF) gene mutation, hyperhomocysteinemia, and protein C deficiency.
Hyperhomocysteinemia
Na VPA-induced acute ischemic stroke in an epileptic patient with methylenetetrahydrofolate reductase gene polymorphism.
Hyperhomocysteinemia
Neonatal and fetal methylenetetrahydrofolate reductase genetic polymorphisms: an examination of C677T and A1298C mutations.
Hyperhomocysteinemia
No association between MTHFR gene polymorphism and diabetic nephropathy in Japanese type II diabetic patients with proliferative diabetic retinopathy.
Hyperhomocysteinemia
No association between the MTHFR A1298C and transcobalamin C776G genetic polymorphisms and hyperhomocysteinemia in thrombotic disease.
Hyperhomocysteinemia
No association of C677T methylenetetrahydrofolate reductase and an endothelial nitric oxide synthase polymorphism with recurrent pregnancy loss.
Hyperhomocysteinemia
No associations of Helicobacter pylori infection and gastric atrophy with plasma total homocysteine in Japanese.
Hyperhomocysteinemia
No interaction between factor V Leiden and hyperhomocysteinemia or MTHFR 677TT genotype in venous thrombosis. Results of a meta-analysis of published studies and a large case-only study.
Hyperhomocysteinemia
Non-alcoholic fatty liver disease (NAFLD) and MTHFR 1298A > C gene polymorphism.
Hyperhomocysteinemia
Novel insights into the development of portal vein thrombosis in cirrhosis patients.
Hyperhomocysteinemia
Nutri-epigenetics ameliorates blood-brain barrier damage and neurodegeneration in hyperhomocysteinemia: role of folic acid.
Hyperhomocysteinemia
Nutrigenetic impact of daily folate intake on plasma homocysteine and folate levels in patients with different methylenetetrahydrofolate reductase genotypes.
Hyperhomocysteinemia
Pediatric stroke and methylenetetrahydrofolate reductase polymorphisms: an examination of C677T and A1298C mutations.
Hyperhomocysteinemia
Phenotypic variability of cardiovascular manifestations in Marfan Syndrome. Possible role of hyperhomocysteinemia and C677T MTHFR gene polymorphism.
Hyperhomocysteinemia
Plasma homocysteine and the methylenetetrahydrofolate reductase C677T gene variant: lack of association with schizophrenia.
Hyperhomocysteinemia
Plasma homocysteine and vitamin B12 serum levels, red blood cell folate concentrations, C677T methylenetetrahydrofolate reductase gene mutation and risk of recurrent miscarriage: a case-control study in Spain.
Hyperhomocysteinemia
Plasma homocysteine concentration in children with chronic renal failure.
Hyperhomocysteinemia
Plasma homocysteine levels & 677C-->T methylenetetrahydrofolate reductase gene polymorphism in patients with coronary artery disease of different severity.
Hyperhomocysteinemia
Plasma homocysteine levels related to interactions between folate status and methylenetetrahydrofolate reductase: a study in 52 healthy subjects.
Hyperhomocysteinemia
Plasma homocysteine levels, methylene tetrahydrofolate reductase A1298C gene polymorphism and risk of retinal vein thrombosis.
Hyperhomocysteinemia
Plasma homocysteine, methylenetetrahydrofolate reductase genotypes, and age at onset of symptoms of myocardial ischemia.
Hyperhomocysteinemia
Plasma homocysteine, methylenetetrahydrofolate reductase mutation and carotid damage in elderly healthy women.
Hyperhomocysteinemia
Plasma hyperhomocysteinemia, MTHFR polymorphism and thromboembolic disease: an example of gene-nutrition interactions in chronic disease.
Hyperhomocysteinemia
Plasma Serotonin is Elevated in Adult Patients with Sudden Sensorineural Hearing Loss.
Hyperhomocysteinemia
Plasma total homocysteine level and methylenetetrahydrofolate reductase 677C>T genetic polymorphism in Japanese patients with rheumatoid arthritis.
Hyperhomocysteinemia
Plasma total homocysteine levels in children with type 1 diabetes: relationship with vitamin status, methylene tetrahydrofolate reductase genotype, disease parameters and coronary risk factors.
Hyperhomocysteinemia
Plasminogen activator inhibitor-1, factor V, factor II and methylenetetrahydrofolate reductase polymorphisms in women with recurrent miscarriage.
Hyperhomocysteinemia
Polymorphism in methylenetetrahydrofolate reductase gene: its impact on plasma homocysteine levels and carotid atherosclerosis in ESRD patients receiving hemodialysis.
Hyperhomocysteinemia
Polymorphism of MTHFR C677T, serum vitamin levels and cognition in subjects with hyperhomocysteinemia in China.
Hyperhomocysteinemia
Polymorphism of the methylenetetrahydrofolate reductase gene association with homocysteine and ischemic stroke in type 2 diabetes.
Hyperhomocysteinemia
Polymorphisms in MTHFR and MTRR genes associated with blood plasma homocysteine concentration and sperm counts.
Hyperhomocysteinemia
Polymorphisms in the CBS gene and homocysteine, folate and vitamin B12 levels: association with polymorphisms in the MTHFR and MTRR genes in Brazilian children.
Hyperhomocysteinemia
Polymorphisms in the methylenetetrahydrofolate reductase and methionine synthase reductase genes and homocysteine levels in Brazilian children.
Hyperhomocysteinemia
Polymorphisms of methylenetetrahydrofolate reductase gene as the genetic predispositions of coronary artery diseases in eastern India.
Hyperhomocysteinemia
POSITIVE EFFECT OF BETAINE-ARGININE SUPPLEMENT ON IMPROVED HYPERHOMOCYSTEINEMIA TREATMENT IN MARRIED COUPLES WITH REPRODUCTIVE DISORDERS.
Hyperhomocysteinemia
Posterior cerebral artery occlusion after Mycoplasma pneumoniae infection associated with genetic defect of MTHFR C677T.
Hyperhomocysteinemia
Predicting Hyperhomocysteinemia by Methylenetetrahydrofolate Reductase C677T Polymorphism in Chinese Patients With Hypertension.
Hyperhomocysteinemia
Prediction of ischemic stroke in young Indians: is thrombophilia profiling a way out?
Hyperhomocysteinemia
Premature arterial and venous events in three families. Effect of folate levels and MTHFR mutation mediated by family/generation and homocysteine levels.
Hyperhomocysteinemia
Prevalence of hyperhomocysteinemia and the MTHFR C677T polymorphism in patients with arterial and venous thrombosis from North Western Russia.
Hyperhomocysteinemia
Prevalence of methylenetetrahydrofolate reductase C677T and A1298C polymorphisms in Taiwanese patients with Type 2 diabetic mellitus.
Hyperhomocysteinemia
Prevalence of methylenetetrahydrofolate reductase gene polymorphisms (C677T, and A1298C) among Saudi children receiving dental treatment.
Hyperhomocysteinemia
Prevalence of myocardial infarction is related to hyperhomocysteinemia but not influenced by C677T methylenetetrahydrofolate reductase and A2756G methionine synthase polymorphisms in diabetic and non-diabetic subjects.
Hyperhomocysteinemia
Recurrent small-artery disease in hyperhomocysteinemia: widowers' stroke syndrome?
Hyperhomocysteinemia
Relation between folate status, a common mutation in methylenetetrahydrofolate reductase, and plasma homocysteine concentrations.
Hyperhomocysteinemia
Relation of a common methylenetetrahydrofolate reductase mutation and plasma homocysteine with intimal hyperplasia after coronary stenting.
Hyperhomocysteinemia
Relationship between thiolactonase activity and hyperhomocysteinemia according to MTHFR gene polymorphism in Tunisian Behçet's disease patients.
Hyperhomocysteinemia
Relationship of MTHFR gene polymorphisms with renal and cardiac disease.
Hyperhomocysteinemia
Renal Insufficiency in Non-Diabetic Subjects: Relationship of MTHFR C677t Gene Polymorphism and Left Ventricular Hypertrophy.
Hyperhomocysteinemia
Retinal ganglion cell loss and mild vasculopathy in methylene tetrahydrofolate reductase (Mthfr) deficient mice: a model of mild hyperhomocysteinemia.
Hyperhomocysteinemia
Retinal vein occlusion, homocysteine, and methylene tetrahydrofolate reductase genotype.
Hyperhomocysteinemia
Retinal vein occlusion: a form of venous thrombosis or a complication of atherosclerosis? A meta-analysis of thrombophilic factors.
Hyperhomocysteinemia
Risk of recurrent venous thrombosis in patients with G20210A mutation in the prothrombin gene or factor V Leiden mutation.
Hyperhomocysteinemia
Risk of Venous Thrombosis in Carriers of a Common Mutation in the Homocysteine Regulatory Enzyme Methylenetetrahydrofolate Reductase.
Hyperhomocysteinemia
Risk-factor profile in severe, generalized, obliterating vascular disease.
Hyperhomocysteinemia
Role of a common mutation in the homocysteine regulatory enzyme methylenetetrahydrofolate reductase in ischemic stroke.
Hyperhomocysteinemia
Role of Genetic and Acquired Prothrombotic Risk Factors in Genesis of Sudden Sensorineural Hearing Loss.
Hyperhomocysteinemia
Role of genetic changes in the progression of cardiovascular diseases.
Hyperhomocysteinemia
Role of Hyperhomocysteinemia and Methylene Tetrahydrofolate Reductase C677T Polymorphism in Idiopathic Portal Vein Thrombosis.
Hyperhomocysteinemia
Role of thrombotic vascular risk factors in inflammatory bowel disease.
Hyperhomocysteinemia
Screening for C677T and A1298C MTHFR polymorphisms in patients with epilepsy and risk of hyperhomocysteinemia.
Hyperhomocysteinemia
Segmental renal artery thrombosis secondary to methylene tetrahydrofolate reductase mutation: an unusual presentation.
Hyperhomocysteinemia
Severe and mild mutations in cis for the methylenetetrahydrofolate reductase (MTHFR) gene, and description of five novel mutations in MTHFR.
Hyperhomocysteinemia
Sex-specific effect of the thermolabile C677T mutation in the methylenetetrahydrofolate reductase gene on angiographically assessed coronary artery disease in Brazilians.
Hyperhomocysteinemia
Single nucleotide polymorphisms in homocysteine metabolism pathway genes: association of CHDH A119C and MTHFR C677T with hyperhomocysteinemia.
Hyperhomocysteinemia
Socio-economic disparities in preterm birth: causal pathways and mechanisms.
Hyperhomocysteinemia
Splenic thrombosis in three patients with moderate hyperhomocysteinemia, low folate and the C677T variant of the methylenetetrahydrofolate reductase (MTHFR) gene.
Hyperhomocysteinemia
Study on homocysteine levels and methylenetetrahydrofolate reductase gene variant (C677T) in a population of Buenos Aires city.
Hyperhomocysteinemia
Study on Maternal SNPs of MTHFR Gene and HCY Level Related to Congenital Heart Diseases.
Hyperhomocysteinemia
Sudden sensorineural hearing loss: A vascular cause? Analysis of prothrombotic risk factors in head and neck.
Hyperhomocysteinemia
Systemic risk factors correlated with hyperhomocysteinemia for specific MTHFR C677T genotypes and sex in the Chinese population.
Hyperhomocysteinemia
The 1298A-->C polymorphism in methylenetetrahydrofolate reductase (MTHFR): in vitro expression and association with homocysteine.
Hyperhomocysteinemia
The 5,10-methylenetetrahydrofolate reductase C677T polymorphism interacts with smoking to increase homocysteine.
Hyperhomocysteinemia
The 894G > T (Glu298Asp) Variant in the Endothelial NOS Gene and MTHFR Polymorphisms Influence Homocysteine Levels in Patients with Cognitive Decline.
Hyperhomocysteinemia
The active site of oxidative phosphorylation and the origin of hyperhomocysteinemia in aging and dementia.
Hyperhomocysteinemia
The association of the MTHFR C677T polymorphism with inflammatory bowel diseases in the Israeli Jewish population: An example of genetic heterogeneity.
Hyperhomocysteinemia
The C677T mutation in methylenetetrahydrofolate reductase gene, plasma homocysteine concentration and the risk of coronary artery disease.
Hyperhomocysteinemia
The C677T mutation in the methylenetetrahydrofolate reductase gene contributes to hyperhomocysteinemia in patients taking anticonvulsants.
Hyperhomocysteinemia
The C677T mutation in the methylenetetrahydrofolate reductase gene predisposes to hyperhomocysteinemia in children with familial hypercholesterolemia treated with cholestyramine.
Hyperhomocysteinemia
The C677T polymorphism of the methylenetetrahydrofolate reductase gene is associated with the level of decrease on diastolic blood pressure in essential hypertension patients treated by angiotensin-converting enzyme inhibitor.
Hyperhomocysteinemia
The C677T thermolabile variant of methylene tetrahydrofolate reductase on homocysteine, folate and vitamin B12 in a hemodialysis center.
Hyperhomocysteinemia
The common mutations C677T and A1298C in the human methylenetetrahydrofolate reductase gene are associated with hyperhomocysteinemia and cardiovascular disease in hemodialysis patients.
Hyperhomocysteinemia
The communal relation of MTHFR, MTR, ACE gene polymorphisms and hyperhomocysteinemia as conceivable risk of coronary artery disease.
Hyperhomocysteinemia
The effect of methylenetetrahydrofolate reductase C677T common variant on hypertensive risk is not solely explained by increased plasma homocysteine values.
Hyperhomocysteinemia
The effect of polymorphisms of MTHER gene and vitamin B on hyperhomocysteinemia.
Hyperhomocysteinemia
The frequency of Raynauds phenomenon in patients with methylenetetrahydrofolate reductase gene mutation and hyperhomocysteinemia
Hyperhomocysteinemia
The graded effect of hyperhomocysteinemia on the severity and extent of coronary atherosclerosis.
Hyperhomocysteinemia
The homozygous C677T mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for migraine.
Hyperhomocysteinemia
The importance of folate, vitamins B6 and B12 for the lowering of homocysteine concentrations for patients with recurrent pregnancy loss and MTHFR mutations.
Hyperhomocysteinemia
The methylenetetrahydrofolate reductase (MTHFR) 677C-->T mutation and cardiovascular risk--A case of ischemic stroke and acute myocardial infarction.
Hyperhomocysteinemia
The methylenetetrahydrofolate reductase C677T gene mutation is associated with hyperhomocysteinemia, cardiovascular disease and plasma B-type natriuretic peptide levels in Korea.
Hyperhomocysteinemia
The methylenetetrahydrofolate reductase C677T polymorphism is a major determinant of coffee-induced increase of plasma homocysteine: a randomized placebo controlled study.
Hyperhomocysteinemia
The methylenetetrahydrofolate reductase TT677 genotype is associated with venous thrombosis independently of the coexistence of the FV Leiden and the prothrombin A20210 mutation.
Hyperhomocysteinemia
The MTHFR 677 C/T polymorphism influences plasma levels of adhesion molecules and nitric oxide.
Hyperhomocysteinemia
The MTHFR C677T polymorphism modifies age at onset in Parkinson's disease.
Hyperhomocysteinemia
The pathophysiological hypothesis of homocysteine thiolactone-mediated vascular disease.
Hyperhomocysteinemia
The relation between erythrocyte volume and folate levels is influenced by a common mutation in the methylenetetrahydrofolate reductase (MTHFR) gene (C677T).
Hyperhomocysteinemia
The relationship between riboflavin and plasma total homocysteine in the Framingham Offspring cohort is influenced by folate status and the C677T transition in the methylenetetrahydrofolate reductase gene.
Hyperhomocysteinemia
The relationship of the methylenetetrahydrofolate reductase C677T gene polymorphism in Turkish type 2 diabetic patients with and without nephropathy.
Hyperhomocysteinemia
The role of hyperhomocysteinemia and methylenetetrahydrofolate reductase (MTHFR) C677T mutation in patients with retinal artery occlusion.
Hyperhomocysteinemia
The role of methylenetetrahydrofolate reductase C677T polymorphism on the peripheral blood natural killer cell proportion in women with unexplained recurrent miscarriages.
Hyperhomocysteinemia
The role of vitamin B12 in fasting hyperhomocysteinemia and its interaction with the homozygous C677T mutation of the methylenetetrahydrofolate reductase (MTHFR) gene. A case-control study of patients with early-onset thrombotic events.
Hyperhomocysteinemia
The roles of methylenetetrahydrofolate reductase 677C>T and 1298A>C polymorphisms in moyamoya disease patients.
Hyperhomocysteinemia
The structure and properties of methylenetetrahydrofolate reductase from Escherichia coli suggest how folate ameliorates human hyperhomocysteinemia.
Hyperhomocysteinemia
The thermolabile variant 677C-->T can further reduce activity when expressed in cis with severe mutations for human methylenetetrahydrofolate reductase.
Hyperhomocysteinemia
Thromboembolic tendency (TE) in IBD (Inflammatory bowel disease) patients.
Hyperhomocysteinemia
Thrombophilia in hemodialysis patients: Transfer to peritoneal dialysis is life saving.
Hyperhomocysteinemia
Thrombophilias as risk factors for disorders of pregnancy and fetal damage.
Hyperhomocysteinemia
Thrombophilic risk factors in patients with severe carotid atherosclerosis.
Hyperhomocysteinemia
Total homocysteine, folate, and cobalamin, and their relation to genetic polymorphisms, lifestyle and body mass index in healthy children and adolescents.
Hyperhomocysteinemia
Treatment of Erectile Dysfunction Due to C677T Mutation of the MTHFR Gene with Vitamin B6 and Folic acid in Patients Non Responders to PDE5i.
Hyperhomocysteinemia
Two siblings with a homozygous MTHFR C677T (G80A-RFC1) mutation and stroke.
Hyperhomocysteinemia
Unique holoenzyme dimers of the tetrameric enzyme Escherichia coli methylenetetrahydrofolate reductase: characterization of structural features associated with modulation of the enzyme's function.
Hyperhomocysteinemia
Vascular and cellular stress in inflammatory bowel disease: revisiting the role of homocysteine.
Hyperhomocysteinemia
Venous thromboembolism associated with hyperhomocysteinemia, homozygosity for the methylenetetrahydrofolate reductase 677C>T gene variant, and secondary polycythemia.
Hyperhomocysteinemia
Wandering spleen: 'presentation in adolescent with high thrombotic risk'
Hyperhomocysteinemia
[A clinical study of hyperhomocysteinemia in rheumatological diseases.]
Hyperhomocysteinemia
[A hyperhomocysteinemia study in a population with a familial factor for acute myocardial infarct and sudden cardiac death at a young age]
Hyperhomocysteinemia
[Acute cerebral sinus-thrombosis due to polyangiitis overlap syndrome with granulomatosis with polyangiitis (Wegener's granulomatosis) and eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome)].
Hyperhomocysteinemia
[Association of hyperhomocysteinemia with liver steatosis in patients with chronic hepatitis C].
Hyperhomocysteinemia
[C677T genetic polymorphism of methylenetetrahydrofolate reductase in premature coronary heart disease]
Hyperhomocysteinemia
[Cerebral vascular complication of hyperhomocysteinemia. Controlling thromboembolic complications with folates]
Hyperhomocysteinemia
[Effect of hyperhomocysteinemia and methylenetetrahydrofolate reductase 677C --> T mutation in venous thromboembolism risk of young adults]
Hyperhomocysteinemia
[Factors determining hyperhomocysteinemia in the chronic phase of strokes]
Hyperhomocysteinemia
[Features of allele polymorphism of genes involved in homocysteine and folate metabolism in patients with atherosclerosis of the lower extremity arteries]
Hyperhomocysteinemia
[Homocysteine, 5,10-methylenetetrahydrofolate reductase and deep venous thrombosis. Survey of 120 patients in internal medicine]
Hyperhomocysteinemia
[Homocysteinemia and its relationship with the methylentetrahydrofolate reductase polymorphism in various ethnic groups from western Venezuela]
Hyperhomocysteinemia
[Hyperhomocysteinemia and C677T mutation of methylenetetrahydrofolate reductase]
Hyperhomocysteinemia
[Hyperhomocysteinemia: an independent risk factor or a simple marker of vascular disease?. 1. Basic data]
Hyperhomocysteinemia
[Hyperhomocysteinemia: associated obstetric diabetes and fetal malformations]
Hyperhomocysteinemia
[Levels of homocysteine and polymorphisms of homocysteine metabolism-related enzymes in patients with type 2 diabetes mellitus and coronary heart disease]
Hyperhomocysteinemia
[Lowering high levels of fasting total homocysteine with folic acid and vitamins B in patients with venous thromboembolism: relationship between response and the C677T methylenetetrahydrofolate reductase (MTHRF) genotype]
Hyperhomocysteinemia
[Methylenetetrahydrofolate reductase deficiency-induced schizophrenia in a school-age boy].
Hyperhomocysteinemia
[Methylenetetrahydrofolate reductase gene polymorphism and plasma homocysteine levels in hemodialysing patients]
Hyperhomocysteinemia
[Methylenetetrahydrofolate reductase polymorphism C677T in patients with consolidated fractures and pseudarthrosis of long bones: relationship with homocystein and inflammatory mediators].
Hyperhomocysteinemia
[Portal and mesenteric vein thrombosis associated with hyperhomocysteinemia and pernicious anemia in a patient heterozygous for the MTHFR C677T mutation.]
Hyperhomocysteinemia
[Prevalence of methylenetetrahydrofolate reductase C677T mutation among patients with acute ischemic cerebrovascular disease in Aragon]
Hyperhomocysteinemia
[Promoters of genes MTHFR from patients with hyperhomocysteinemia and PTEN from patients with malignant and benign endometrial and ovarian tumors]
Hyperhomocysteinemia
[THE DIFFERENTIATED APPROACH TO PREVENTION OF NEURAL TUBE DEFECTS IN CHILDREN].
Hyperhomocysteinemia
[The relationship between the plasma homocysteine level and the polymorphism of MTHFR gene C667T in liver cirrhosis]
Hyperhomocysteinemia
[The role of homocysteine and methylenetetrahydrofolate reductase, methionine synthase, methionine synthase reductase polymorphisms in the development of cardiovascular diseases and hypertension].
Hyperinsulinism
Effects of a high-fat-sucrose diet on enzymes in homocysteine metabolism in the rat.
Hyperlipidemias
Association of MTHFR genetic polymorphisms with venous thromboembolism in Uyghur population in Xinjiang, China.
Hyperlipidemias
Effect of simvastatin on plasma homocysteine levels and its modification by MTHFR C677T polymorphism in Chinese patients with primary hyperlipidemia.
Hyperlipidemias
MTHFR C677T polymorphism is associated with hyperlipidemia in women with polycystic ovary syndrome.
Hyperlipidemias
Plasma homocysteine and gene polymorphisms associated with the risk of hyperlipidemia in northern Chinese subjects.
Hyperlipidemias
[Association of C677T gene polymorphisms of methylenetetrahydrofolate reductase and plasma homocysteine level with hyperlipidemia].
Hyperlipoproteinemia Type II
Association of C677T polymorphism in MTHFR gene, high homocysteine and low HDL cholesterol plasma values in heterozygous familial hypercholesterolemia.
Hyperlipoproteinemia Type II
Effect of common methylenetetrahydrofolate reductase gene mutation on coronary artery disease in familial hypercholesterolemia.
Hyperlipoproteinemia Type II
Serum homocysteine, methylenetetrahydrofolate reductase gene polymorphism and cardiovascular disease in heterozygous familial hypercholesterolemia.
Hyperlipoproteinemia Type II
The C677T mutation in the methylenetetrahydrofolate reductase gene predisposes to hyperhomocysteinemia in children with familial hypercholesterolemia treated with cholestyramine.
Hyperlipoproteinemias
The association of MTHFR C677T gene variants and lipid profiles or body mass index in patients with diabetic and nondiabetic coronary heart disease.
Hyperparathyroidism
Renal Insufficiency in Non-Diabetic Subjects: Relationship of MTHFR C677t Gene Polymorphism and Left Ventricular Hypertrophy.
Hypersensitivity
The association between mother and child MTHFR C677T polymorphisms, dietary folate intake and childhood atopy in a population-based, longitudinal birth cohort.
Hypersensitivity
[A case of acute lymphoblastic leukemia of MTHFR C677T gene positive with methotrexate hypersensitivity was successfully rescued by hemodialysis].
Hypertension
5,10-Methylenetetrahydrofolate reductase polymorphism and early organ damage in primary hypertension.
Hypertension
A case of vascular parkinsonism associated with hyperhomocysteinemia and methylenetetrahydrofolate reductase gene variant (C677T).
Hypertension
A common mutation in methylenetetrahydrofolate reductase gene among the Japanese population.
Hypertension
A meta-analysis of association between C677T polymorphism in the methylenetetrahydrofolate reductase gene and hypertension.
Hypertension
A prospective cohort study of MTHFR C677T gene polymorphism and its influence on the therapeutic effect of homocysteine in stroke patients with hyperhomocysteinemia.
Hypertension
Addressing optimal folate and related B-vitamin status through the lifecycle: health impacts and challenges.
Hypertension
Age and hypertension related changes in genotypes of MTHFR 677C>T, 1298A>C and PON1 -108C>T SNPs in men with coronary artery disease (CAD).
Hypertension
Analysis of genetic polymorphisms related to thrombosis and other risk factors in patients with retinal vein occlusion.
Hypertension
Analysis of metabolism-related indicators and MTHFR gene polymorphism in patients with H-type hypertension.
Hypertension
Analysis of polymorphisms in genes (AGT, MTHFR, GPIIIa, and GSTP1) associated with hypertension, thrombophilia and oxidative stress in Mestizo and Amerindian populations of México.
Hypertension
Association between the MTHFR C677T gene polymorphism and essential hypertension in South West Cameroon.
Hypertension
Association of 77 polymorphisms in 52 candidate genes with blood pressure progression and incident hypertension: the Women's Genome Health Study.
Hypertension
Association of a methylene tetrahydrofolate reductase C677T polymorphism with several blood chemical levels in a Chinese population.
Hypertension
Association of C677T polymorphism in the methylenetetrahydrofolate reductase gene with hypertension in pregnancy and pre-eclampsia: a meta-analysis.
Hypertension
Association of common variants in/near six genes (ATP2B1, CSK, MTHFR, CYP17A1, STK39 and FGF5) with blood pressure/hypertension risk in Chinese children.
Hypertension
Association of COMT G675A and MTHFR C677T polymorphisms with hypertensive disorders of pregnancy in Mexican mestizo population.
Hypertension
Association of gene polymorphisms with myocardial infarction in individuals with or without conventional coronary risk factors.
Hypertension
Association of Methylene Tetrahydrofolate Reductase C677T Genotype With Type 2 Diabetes Mellitus Patients With and Without Renal Complications.
Hypertension
Association of methylenetetrahydrofolate reductase gene (C677T) with the risk of hypertension in Morocco.
Hypertension
Association of Methylenetetrahydrofolate Reductase Gene 677C>T Polymorphism with Hypertension in Older Women in a Population of Buenos Aires City.
Hypertension
Association of methylenetetrahydrofolate reductase gene C677T polymorphism with polycystic ovary syndrome risk: a systematic review and meta-analysis update.
Hypertension
Association of methylenetetrahydrofolate reductase gene polymorphism with carotid atherosclerosis depending on smoking status in a Japanese general population.
Hypertension
Association of MTHFR genetic polymorphisms with venous thromboembolism in Uyghur population in Xinjiang, China.
Hypertension
Association of single nucleotide polymorphisms of MTHFR, TCN2, RNF213 with susceptibility to hypertension and blood pressure.
Hypertension
Associations of MTHFR and MTRR Polymorphisms With Serum Lipid Levels in Chinese Hypertensive Patients.
Hypertension
Associations of MTHFR Gene Polymorphisms with Hypertension and Hypertension in Pregnancy: A Meta-Analysis from 114 Studies with 15411 Cases and 21970 Controls.
Hypertension
Associations of plasma homocysteine and the methylenetetrahydrofolate reductase C677T polymorphism with carotid intima media thickness among South Asian, Chinese and European Canadians.
Hypertension
Blood pressure and hypertension are associated with 7 loci in the Japanese population.
Hypertension
Blood pressure in treated hypertensive individuals with the MTHFR 677TT genotype is responsive to intervention with riboflavin: findings of a targeted randomized trial.
Hypertension
C677T polymorphism of the 5,10 MTHFR gene in young Mexican subjects with ST-elevation myocardial infarction.
Hypertension
Case-control Study of methylenetetrahydrofolate reductase mutations and hyperhomocysteinemia and risk of stroke.
Hypertension
Clinical characteristics of H-type hypertension and its relationship with the MTHFR C677T polymorphism in a Zhuang population from Guangxi, China.
Hypertension
Common variants in or near FGF5, CYP17A1 and MTHFR genes are associated with blood pressure and hypertension in Chinese Hans.
Hypertension
Connection between small vessel disease related stroke and the MTHFR C677T polymorphism in a Hungarian population.
Hypertension
Critical review of nutrition, blood pressure and risk of hypertension through the lifecycle: do B vitamins play a role?
Hypertension
DNA methylation of hypertension-related genes and effect of riboflavin supplementation in adults stratified by genotype for the MTHFR C677T polymorphism.
Hypertension
Dynamic regulation of MTHFR mRNA expression and C677T genotype modulate mortality in coronary artery disease patients after revascularization.
Hypertension
Effects of methionine synthase and methionine synthase reductase polymorphisms on hypertension susceptibility.
Hypertension
Effects of MTHFR and MS gene polymorphisms on baseline blood pressure and Benazepril effectiveness in Chinese hypertensive patients.
Hypertension
Epistasis analysis of metabolic genes polymorphisms associated with ischemic heart disease in Yucatan.
Hypertension
Evidence of a Role for One-Carbon Metabolism in Blood Pressure: Can B Vitamin Intervention Address the Genetic Risk of Hypertension Owing to a Common Folate Polymorphism?
Hypertension
Evidence on the causal link between homocysteine and hypertension from a meta-analysis of 40 173 individuals implementing Mendelian randomization.
Hypertension
Functional Polymorphism rs13306560 of the MTHFR Gene Is Associated With Essential Hypertension in a Mexican-Mestizo Population.
Hypertension
Genetic and environmental influences on total plasma homocysteine and coronary artery disease (CAD) risk among South Indians.
Hypertension
Genetic polymorphism of 5,10-methylenetetrahydrofolate increases risk of myocardial infarction and is correlated to elevated levels of homocysteine in the Japanese general population.
Hypertension
Genetic thromobophilia in pregnancy: a case-control study among North Indian women.
Hypertension
Homocysteine and nitrite levels are modulated by MTHFR 677C>T polymorphism in obese women treated with simvastatin.
Hypertension
Homocysteine and the C677T Gene Polymorphism of Its Key Metabolic Enzyme MTHFR Are Risk Factors of Early Renal Damage in Hypertension in a Chinese Han Population.
Hypertension
Homocysteine, the MTHFR 677C>T polymorphism and hypertension: effect modifiers by lifestyle factors and population subgroups.
Hypertension
Homozygous methylentetrahydrofolate reductase C667T genotype anticipates age at venous thromboembolism by one decade.
Hypertension
Impact of the common MTHFR 677C?T polymorphism on blood pressure in adulthood and role of riboflavin in modifying the genetic risk of hypertension: evidence from the JINGO project.
Hypertension
Impact of the MTHFR C677T polymorphism on one-carbon metabolites: Evidence from a randomised trial of riboflavin supplementation.
Hypertension
Individual and Joint Associations of Methylenetetrahydrofolate Reductase C677T Genotype and Plasma Homocysteine With Dyslipidemia in a Chinese Population With Hypertension.
Hypertension
Interactions between the single nucleotide polymorphisms in the homocysteine pathway (MTHFR 677C>T, MTHFR 1298 A>C, and CBSins) and the efficacy of HMG-CoA reductase inhibitors in preventing cardiovascular disease in high-risk patients of hypertension: the GenHAT study.
Hypertension
Interactions of Methylenetetrahydrofolate Reductase C677T Polymorphism with Environmental Factors on Hypertension Susceptibility.
Hypertension
Interrelation of cardiovascular risk factors with high albuminury among patients with arterial hypertension living in Mountain Shoriya.
Hypertension
Investigation of homocysteine-pathway-related variants in essential hypertension.
Hypertension
Is there any genetic predisposition of MMP-9 gene C1562T and MTHFR gene C677T polymorphisms with essential hypertension?
Hypertension
Joint associations of folate, homocysteine and MTHFR, MTR and MTRR gene polymorphisms with dyslipidemia in a Chinese hypertensive population: a cross-sectional study.
Hypertension
Lack of association between methylenetetrahydrofolate reductase (MTHFR) C677T and ischaemic heart disease (IHD): family-based association study in a Spanish population.
Hypertension
Low plasma pyridoxal 5'-phosphate concentration and MTHFR 677C-->T genotypes are associated with increased risk of hypertension.
Hypertension
MAT1A variants are associated with hypertension, stroke, and markers of DNA damage and are modulated by plasma vitamin B-6 and folate.
Hypertension
Methylenetetrahydrofolate reductase (MTHFR) polymorphism A1298C (Glu429Ala) predicts decline in renal function over time in the African-American Study of Kidney Disease and Hypertension (AASK) Trial and Veterans Affairs Hypertension Cohort (VAHC).
Hypertension
Methylenetetrahydrofolate Reductase C677T Gene Polymorphism as a Risk Factor for Hypertension in a Rural Population.
Hypertension
Methylenetetrahydrofolate reductase C677T polymorphism, hypertension and risk of stroke: a prospective, nested case-control study.
Hypertension
Methylenetetrahydrofolate reductase gene polymorphism and risk of premature myocardial infarction.
Hypertension
Methylenetetrahydrofolate reductase gene polymorphism, global DNA methylation and blood pressure: a population based study from North India.
Hypertension
Methylenetetrahydrofolate reductase gene polymorphism: relation to blood pressure and cerebrovascular disease.
Hypertension
Methylenetetrahydrofolate reductase gene polymorphisms in essential hypertension relation: with the development of hypertensive end-stage renal disease.
Hypertension
Methylenetetrahydrofolate reductase polymorphism (C677T), hyperhomocysteinemia, and risk of ischemic cardiovascular disease and venous thromboembolism: prospective and case-control studies from the Copenhagen City Heart Study.
Hypertension
Methylenetetrahydrofolate reductase polymorphism 677C>T is associated with peripheral arterial disease in type 2 diabetes.
Hypertension
Methylenetetrahydrofolate reductase polymorphism, folate, and susceptibility to preeclampsia.
Hypertension
Methylenetetrahydrofolate reductase variants associated with hypertension and cardiovascular disease interact with dietary polyunsaturated Fatty acids to modulate plasma homocysteine in puerto rican adults.
Hypertension
Modeling premature occurrence of acute coronary syndrome with atherogenic and thrombogenic risk factors and gene markers in extended families.
Hypertension
MTHFR 677 CT/MTHFR 1298 CC genotypes are associated with increased risk of hypertension in Indians.
Hypertension
MTHFR C677T polymorphism affects normotensive diastolic blood pressure independently of blood lipids.
Hypertension
Plasma homocysteine, MTHFR C677T, CBS 844ins68bp, and MTHFD1 G1958A polymorphisms in spontaneous cervical artery dissections.
Hypertension
Plasma total homocysteine levels and methylenetetrahydrofolate reductase gene polymorphism in patients with type 2 diabetes mellitus.
Hypertension
Polymorphism of methylenetetrahydrofolate reductase gene (C677T MTHFR) is not a confounding factor of the relationship between serum uric acid level and the prevalence of hypertension in Japanese men.
Hypertension
Polymorphism of MTHFR C677T Gene and the Associations with the Severity of Essential Hypertension in Northern Chinese Population.
Hypertension
Postgraduate Symposium: The MTHFR C677T polymorphism, B-vitamins and blood pressure.
Hypertension
PP004. The polymorphism C677T of methylenetetrahydrofolate reductase (MTHFR), may increase risk for future higher blood pressure in women with previous hypertension in pregnancy.
Hypertension
Predicting Hyperhomocysteinemia by Methylenetetrahydrofolate Reductase C677T Polymorphism in Chinese Patients With Hypertension.
Hypertension
Prospective study of first stroke in relation to plasma homocysteine and MTHFR 677C>T and 1298A>C genotypes and haplotypes - evidence for an association with hemorrhagic stroke.
Hypertension
Recapitulation of four hypertension susceptibility genes (CSK, CYP17A1, MTHFR, and FGF5) in East Asians.
Hypertension
Relationship between two sequence variations in the gene for peroxisome proliferator-activated receptor-gamma and plasma homocysteine concentration. Health in men study.
Hypertension
Riboflavin offers a targeted strategy for managing hypertension in patients with the MTHFR 677TT genotype: a 4-y follow-up.
Hypertension
Riboflavin status, MTHFR genotype and blood pressure: current evidence and implications for personalised nutrition.
Hypertension
Riboflavin, MTHFR genotype and blood pressure: A personalized approach to prevention and treatment of hypertension.
Hypertension
Serum levels of miR-199a-5p correlates with blood pressure in premature cardiovascular disease patients homozygous for the MTHFR 677C?>?T polymorphism.
Hypertension
Signaling pathway genes for blood pressure, folate and cholesterol levels among hypertensives: an epistasis analysis.
Hypertension
Strong association of methylenetetrahydrofolate reductase gene C677T polymorphism with hypertension and hypertension-in-pregnancy in Chinese: a meta-analysis.
Hypertension
Study on homocysteine levels and methylenetetrahydrofolate reductase gene variant (C677T) in a population of Buenos Aires city.
Hypertension
Synergistic effects of the MTHFR C677T polymorphism and hypertension on spatial navigation.
Hypertension
The antihypertensive MTHFR gene polymorphism rs17367504-G is a possible novel protective locus for preeclampsia.
Hypertension
The association between inherited thrombophilias and pregnancy-related hypertension recurrence.
Hypertension
The common mutations C677T and A1298C in the human methylenetetrahydrofolate reductase gene are associated with hyperhomocysteinemia and cardiovascular disease in hemodialysis patients.
Hypertension
The effect of methylenetetrahydrofolate reductase C677T common variant on hypertensive risk is not solely explained by increased plasma homocysteine values.
Hypertension
The Hordaland Homocysteine Study: a community-based study of homocysteine, its determinants, and associations with disease.
Hypertension
The importance of MTHFR, MTR, MTRR and CSE expression levels in Caucasian women with preeclampsia.
Hypertension
The methylenetetrahydrofolate reductase (MTHFR) C677T gene polymorphism is associated with breast cancer subtype susceptibility in southwestern China.
Hypertension
The Methylenetetrahydrofolate Reductase C677T (rs1801133) and Apolipoprotein A5-1131T>C (rs662799) Polymorphisms, and Anemia Are Independent Risk Factors for Ischemic Stroke.
Hypertension
The modifying effect of the MTHFR genotype on the association between folic acid supplementation and pulse wave velocity: Findings from the CSPPT.
Hypertension
The prevalence, relative risk factors and MTHFR C677T genotype of H type hypertension of the elderly hypertensives in Shanghai, China: a cross-section study : Prevalence of H type hypertension.
Hypertension
The relationship between MTHFR C677T gene polymorphism and essential hypertension in a sample of an Algerian population of Oran city.
Hypertension
The Role of Polymorphism Gen Methylene Tetra Hydrofolate Reductase (MTHFR) C677T in Ischaemic Stroke Patients with and Without Hypertension.
Hypertension
Total plasma homocysteine is associated with hypertension in Type I diabetic patients.
Hypertension
Volume of white matter hyperintensities in healthy adults: Contribution of age, vascular risk factors, and inflammation-related genetic variants.
Hypertension
Zinc Finger 259 Gene Polymorphism rs964184 is Associated with Serum Triglyceride Levels and Metabolic Syndrome.
Hypertension
[Arterial Hypertension and Methylenetetrahydrofolate Reductase C677T Gene Polymorphism].
Hypertension
[FETAL LOSSES DURING THE MATURATION OF THE PLACENTA AND THE RELATIONSHIP WITH SOME PROCOAGULANT CONDITIONS.]
Hypertension
[Genetic determinants of hypertension in two national cohorts of Mountain Shoria].
Hypertension
[Left Ventricular Myocardial Hypertrophy as a Result of Arterial Hypertension Among Mountain Shoria Population. The Role of Genetic Polymorphism].
Hypertension
[New potential of MTHFR gene variations application as an individual sensitivity marker in evaluation of occupational risk of arterial hypertension under exposure to nose].
Hypertension
[Relationships between polymorphisms of angiotensin-converting enzyme and methylenetetrahydrofolate reductase genes and genetic susceptibility to pregnancy induced hypertension]
Hypertension
[Study on the relationship between methylenetetrahydrofolate reductase gene polymorphism and plasma homocysteine level in pregnancy induced hypertension patients]
Hypertension
[The normotensive carriers of the MTHFR 677T allele, displaying the increased risk of development of the abdominal aortic aneurysm (AAA), occur at the highest frequency among the smoking patients]
Hypertension
[The role of homocysteine and methylenetetrahydrofolate reductase, methionine synthase, methionine synthase reductase polymorphisms in the development of cardiovascular diseases and hypertension].
Hypertension, Pregnancy-Induced
Correlation between MTHFR gene polymorphism and homocysteine levels for prognosis in patients with pregnancy-induced hypertension.
Hypertension, Pregnancy-Induced
Genetic thromobophilia in pregnancy: a case-control study among North Indian women.
Hypertension, Pregnancy-Induced
Localization of folate metabolic enzymes, methionine synthase and 5,10-methylenetetrahydrofolate reductase in human placenta.
Hypertension, Pregnancy-Induced
Methylenetetrahydrofolate Reductase Enzyme Level and Antioxidant Activity in Women with Gestational Hypertension and Pre-eclampsia in Lagos, Nigeria.
Hypertension, Pregnancy-Induced
Methylenetetrahydrofolate reductase polymorphisms and the risk of gestational hypertension.
Hypertension, Pregnancy-Induced
The search for thrombophilic gene mutations in women with gestational hypertension does not help in predicting poor pregnancy outcome.
Hypertension, Pregnancy-Induced
[Relationships between polymorphisms of angiotensin-converting enzyme and methylenetetrahydrofolate reductase genes and genetic susceptibility to pregnancy induced hypertension]
Hypertension, Pregnancy-Induced
[Study on the relationship between methylenetetrahydrofolate reductase gene polymorphism and plasma homocysteine level in pregnancy induced hypertension patients]
Hypertension, Pulmonary
Prevalence of variants in methylenetetrahydrofolate reductase and the severity of pulmonary vascular disease.
Hypertension, Renovascular
Co-existence of renovascular hypertension, polyarteritis nodosa, antiphospholipid syndrome and methylenetetrahydrofolate reductase mutation.
Hypertension, Renovascular
Postoperative Symptomatic Cerebral Infarction in Pediatric Moyamoya Disease: Risk Factors and Clinical Outcome.
Hypertensive Retinopathy
Improving diabetic and hypertensive retinopathy with a medical food containing L-methylfolate: a preliminary report.
Hyperthyroidism
MTHFR gene polymorphisms in hypothyroidism and hyperthyroidism among Jordanian females.
Hyperthyroidism
Postoperative Symptomatic Cerebral Infarction in Pediatric Moyamoya Disease: Risk Factors and Clinical Outcome.
Hypertriglyceridemia
A comparison of the genetic and clinical risk factors for arterial hypertension between indigenous and non-indigenous people of the Shoria Mountain Region.
Hypertriglyceridemia
Associations of homocysteine status and homocysteine metabolism enzyme polymorphisms with hypertension and dyslipidemia in a Chinese hypertensive population.
Hypertriglyceridemia
Hyperhomocysteinemia is associated with hypertriglyceridemia in mice with methylenetetrahydrofolate reductase deficiency.
Hypertriglyceridemia
Joint associations of folate, homocysteine and MTHFR, MTR and MTRR gene polymorphisms with dyslipidemia in a Chinese hypertensive population: a cross-sectional study.
Hypertrophy, Left Ventricular
Relationship Between Gene Polymorphism of Methylenetetrahydrofolate Reductase C677T and Left Ventricular Hypertrophy in Chinese Patients with Chronic Kidney Disease.
Hypertrophy, Left Ventricular
Renal Insufficiency in Non-Diabetic Subjects: Relationship of MTHFR C677t Gene Polymorphism and Left Ventricular Hypertrophy.
Hypoparathyroidism
antiphospholipid antibodies syndrome associated with hyperhomocysteinemia related to MTHFR Gene C677T and A1298C heterozygous mutations in a young man with idiopathic hypoparathyroidism (DiGeorge syndrome).
Hypopituitarism
Combined choroidal neovascularization and hypopituitarism in a patient with homozygous mutation in methylenetetrahydrofolate reductase gene.
Hypoplastic Left Heart Syndrome
Methylenetetrahydrofolate Reductase C677T: Hypoplastic Left Heart and Thrombosis.
Hypospadias
Interaction between MTHFR 677C>T and periconceptional folic acid supplementation in the risk of Hypospadias.
Hypothyroidism
An unusually high plasma concentration of homocysteine resulting from a combination of so-called "secondary" etiologies.
Hypothyroidism
Methylenetetrahydrofolate Reductase (MTHFR) C677T and A1298C Polymorphisms in Georgian Females with Hypothyroidism.
Hypothyroidism
MTHFR GENE C677T POLYMORPHISM AND LEVELS OF DNA METHYLTRASFERASES IN SUBCLINICAL HYPOTHYROIDISM.
Hypothyroidism
MTHFR gene polymorphisms in hypothyroidism and hyperthyroidism among Jordanian females.
Hypoventilation
[Genotype and phenotype analysis of neonates with neonatal encephalopathy complicated with perinatal hypoxic event].
Ichthyosis Vulgaris
[ANALYSIS OF ONE-CARBON METABOLISM GENES AND EPIDERMAL DIFFERENTIATION COMPLEX IN PATIENTS WITH ICHTHYOSIS VULGARIS].
Infections
A systematic review of meta-analyses on gene polymorphisms and gastric cancer risk.
Infections
Association of MTHFR C677T polymorphism with severity and localization of chronic atrophic gastritis patients without Helicobacter pylori infection: a case control study.
Infections
Association of Mycobacterium infections in patients with Mendelian susceptibility to mycobacterial disease with venous thromboembolism.
Infections
Associations between MTHFR Ala222Val polymorphism and risks of hepatitis and hepatitis-related liver cancer: a meta-analysis.
Infections
COVID-19 spreading across world correlates with C677T allele of the methylenetetrahydrofolate reductase (MTHFR) gene prevalence.
Infections
Diagnostic factors identified in 1020 women with two versus three or more recurrent pregnancy losses.
Infections
Distribution of p53, GST, and MTHFR polymorphisms and risk of cervical intraepithelial lesions in sicily.
Infections
Genetic Polymorphism of MTHFR C677T Influences Susceptibility to HBV-Related Hepatocellular Carcinoma in a Chinese Population: a Case-Control Study.
Infections
Impact of methylenetetrahydrofolate reductase C677T polymorphism on the risk of gastric cancer and its interaction with Helicobacter pylori infection.
Infections
Impact of methylenetetrahydrofolate reductase polymorphisms and folate intake on the risk of gastric cancer and their association with Helicobacter pylori infection and tumor site.
Infections
Increased Resistance to Malaria in Mice with Methylenetetrahydrofolate Reductase (Mthfr) Deficiency Suggests a Mechanism for Selection of the MTHFR 677C>T (c.665C>T) Variant.
Infections
Investigation of Methylenetetrahydrofolate Reductase C677T Polymorphism and Human Papilloma Virus Genotypes in Iranian Breast Cancer.
Infections
Lack of association between methylenetetrahydrofolate reductase C677T polymorphism, HPV infection and cervical intraepithelial neoplasia in Brazilian women.
Infections
Methylene Tetrahydrofolate Reductase Gene Polymorphism is Associated with Severity of Liver Steatosis in Chronically Infected Patients with HCV Genotype 4.
Infections
Methylenetetrahydrofolate reductase (MTHFR) deficiency enhances resistance against cytomegalovirus infection.
Infections
Methylenetetrahydrofolate reductase (MTHFR) polymorphisms and promoter methylation in cervical oncogenic lesions and cancer.
Infections
Methylenetetrahydrofolate reductase 677 T allele protects against persistent HBV infection in West Africa.
Infections
Methylenetetrahydrofolate reductase polymorphisms and therapy response in pediatric acute lymphoblastic leukemia.
Infections
MTHFR C677T polymorphism and differential methylation status in gastric cancer: an association with Helicobacter pylori infection.
Infections
MTHFR Polymorphisms and Opisthorchis viverrini Infection: a Relationship with Increased Susceptibility to Cholangiocarcinoma in Thailand.
Infections
No associations of Helicobacter pylori infection and gastric atrophy with plasma total homocysteine in Japanese.
Infections
Possible roles of methylenetetrahydrofolate reductase polymorphism and folate status in patients with early hepatitis C virus genotype 4.
Infections
Posterior cerebral artery occlusion after Mycoplasma pneumoniae infection associated with genetic defect of MTHFR C677T.
Infections
Rapidly progressive psychotic symptoms triggered by infection in a patient with methylenetetrahydrofolate reductase deficiency: a case report.
Infections
The combination of methylenehydrofolate reductase C677T polymorphism screening and gastrointestinal tumor markers detection may be an early screening method for gastrointestinal cancer related to helicobacter pylori infection.
Infections
The effect of methylenetetrahydrofolate reductase polymorphisms on susceptibility to human papilloma virus infection and cervical cancer.
Infections
The Impact of MTHFR 1298 A?>?C and 677 C?>?T Gene Polymorphisms as Susceptibility Risk Factors in Cervical Intraepithelial Neoplasia Related to HPV and Sexually Transmitted Infections.
Infections
The incidence of severe intraventricular hemorrhage based on retrospective analysis of 35939 full-term newborns-report of two cases and review of literature.
Infections
The MTHFR C677T mutation is not a risk factor recognized for HBV-related HCC in a population with a high prevalence of this genetic marker.
Infections
Thrombogenic alleles, Escherichia coli O157:H7 infections, and hemolytic uremic syndrome.
Infections
[C677T polymorphism of the MTHFR gene and the risk of developing distal gastric cancer in a Mexican population]
Infections
[FETAL LOSSES DURING THE MATURATION OF THE PLACENTA AND THE RELATIONSHIP WITH SOME PROCOAGULANT CONDITIONS.]
Infertility
5-Methyltetrahydrofolate reduces blood homocysteine level significantly in C677T methyltetrahydrofolate reductase single-nucleotide polymorphism carriers consulting for infertility.
Infertility
A Association of MTHFR C677T and MTRR A66G Gene Polymorphisms with Iranian Male Infertility and Its Effect on Seminal Folate and Vitamin B12.
Infertility
Association of a miR-34b binding site single nucleotide polymorphism in the 3'-untranslated region of the methylenetetrahydrofolate reductase gene with susceptibility to male infertility.
Infertility
Association of the MTHFR C677T (rs1801133) polymorphism with idiopathic male infertility in a local Pakistani population.
Infertility
Associations of MTHFR DNMT3b 4977 bp deletion in mtDNA and GSTM1 deletion, and aberrant CpG island hypermethylation of GSTM1 in non-obstructive infertility in Indian men.
Infertility
C677T methylenetetrahydrofolate reductase polymorphism interferes with the effects of folic acid and zinc sulfate on sperm concentration.
Infertility
Effects of folic acid on oligozoospermia with MTHFR polymorphisms in term of seminal parameters, DNA fragmentation, and live birth rate: a double-blind, randomized, placebo-controlled trial.
Infertility
Folic acid supplementation and methylenetetrahydrofolate reductase (MTHFR) gene variations in relation to in vitro fertilization pregnancy outcome.
Infertility
Hyperhomocysteinemia in women with unexplained sterility or recurrent early pregnancy loss from Southern Italy: a preliminary report.
Infertility
Infertility in 5,10-methylenetetrahydrofolate reductase (MTHFR)-deficient male mice is partially alleviated by lifetime dietary betaine supplementation.
Infertility
Inherited thrombophilia in infertile women-implication in unexplained infertility.
Infertility
Interaction of thrombophilic SNPs in patients with unexplained infertility-multifactor dimensionality reduction (MDR) model analysis.
Infertility
Methylenetetrahydrofolate reductase C677T polymorphism is not associated with male infertility in a South Indian population.
Infertility
MTHFR (methylenetetrahydrofolate reductase: EC 1.5.1.20) SNPs (single-nucleotide polymorphisms) and homocysteine in patients referred for investigation of fertility.
Infertility
MTHFR C677T and A1298C Genotypes and Haplotypes in Slovenian Couples with Unexplained Infertility Problems and in Embryonic Tissues from Spontaneous Abortions.
Infertility
MTHFR C677T polymorphism, GSTM1 deletion and male infertility: a possible suggestion of a gene-gene interaction?
Infertility
MTHFR promoter hypermethylation in testicular biopsies of patients with non-obstructive azoospermia: the role of epigenetics in male infertility.
Infertility
Polymorphic variants of folate and choline metabolism genes and the risk of endometriosis-associated infertility.
Infertility
Polymorphisms in Folate-Related Enzyme Genes in Idiopathic Infertile Brazilian Men.
Infertility
Polymorphisms in the MTHFR gene influence embryo viability and the incidence of aneuploidy.
Infertility
Prospective study of MTHFR genetic polymorphisms as a possible etiology of male infertility.
Infertility
Relationship Between Genetic Polymorphisms of Methylenetetrahydrofolate Reductase (C677T, A1298C, and G1793A) as Risk Factors for Idiopathic Male Infertility.
Infertility
Role of 677C?T polymorphism a single substitution in methylenetetrahydrofolate reductase (MTHFR) gene in North Indian infertile men.
Infertility
Significant impact of the MTHFR polymorphisms and haplotypes on male infertility risk.
Infertility
Single nucleotide polymorphism C677T in the methylenetetrahydrofolate reductase gene might be a genetic risk factor for infertility for Chinese men with azoospermia or severe oligozoospermia.
Infertility
Spontaneous pregnancies in patients with at least one failed IVF cycle after the management of autoimmune disorders, hereditary thrombophilia, and methylation disorders.
Infertility
Stability of DNA Methylation Patterns in Mouse Spermatogonia Under Conditions of MTHFR Deficiency and Methionine Supplementation.
Infertility
Strain-Specific Defects in Testicular Development and Sperm Epigenetic Patterns in 5,10-Methylenetetrahydrofolate Reductase-Deficient Mice.
Infertility
The relationship between methylenetetrahydrofolate reductase c.677TT genotype and oligozoospermia in infertile male patients living in the Trakya region of Turkey.
Infertility
Thrombophilic mutations in Iranian patients with infertility and recurrent spontaneous abortion.
Infertility
Variations in folate pathway genes are associated with unexplained female infertility.
Infertility
[The occurence of genetic trombophilic markers in patients evaluated for infertility].
Infertility, Female
Hyperhomocysteinemia in women with unexplained sterility or recurrent early pregnancy loss from Southern Italy: a preliminary report.
Infertility, Male
A Association of MTHFR C677T and MTRR A66G Gene Polymorphisms with Iranian Male Infertility and Its Effect on Seminal Folate and Vitamin B12.
Infertility, Male
Association between C677T and A1298C polymorphisms of the MTHFR gene and risk of male infertility: a meta-analysis.
Infertility, Male
Association between genetic polymorphisms in folate-related enzyme genes and infertile men with non-obstructive azoospermia.
Infertility, Male
Association between methionine synthase reductase A66G polymorphism and primary infertility in Chinese males.
Infertility, Male
Association between methylenetetrahydrofolate reductase (MTHFR) gene promoter hypermethylation and the risk of idiopathic male infertility.
Infertility, Male
Association between MTHFR A1298C polymorphism and male infertility: A meta-analysis.
Infertility, Male
Association of a miR-34b binding site single nucleotide polymorphism in the 3'-untranslated region of the methylenetetrahydrofolate reductase gene with susceptibility to male infertility.
Infertility, Male
Association of C677T transition of the human methylenetetrahydrofolate reductase (MTHFR) gene with male infertility.
Infertility, Male
Association of MTHFR, NFKB1, NFKBIA, DAZL and CYP1A1 gene polymorphisms with risk of idiopathic male infertility in a Han Chinese population.
Infertility, Male
Association of the methylenetetrahydrofolate reductase gene A1298C polymorphism with male infertility: a meta-analysis.
Infertility, Male
Association of the methylenetetrahydrofolate reductase gene C677T polymorphism with the risk of male infertility: a meta-analysis.
Infertility, Male
Association of the MTHFR 677C>T and 1298A>C polymorphisms and male infertility risk: a meta-analysis.
Infertility, Male
Association of the MTHFR A1298C variant with unexplained severe male infertility.
Infertility, Male
Association of the MTHFR C677T (rs1801133) polymorphism with idiopathic male infertility in a local Pakistani population.
Infertility, Male
Association study of folate-related enzymes (MTHFR, MTR, MTRR) genetic variants with non-obstructive male infertility in a Polish population.
Infertility, Male
Association study of four polymorphisms in three folate-related enzyme genes with non-obstructive male infertility.
Infertility, Male
Associations of C677T polymorphism in methylenetetrahydrofolate reductase (MTHFR) gene with male infertility risk: A meta-analysis.
Infertility, Male
Associations of MTHFR DNMT3b 4977 bp deletion in mtDNA and GSTM1 deletion, and aberrant CpG island hypermethylation of GSTM1 in non-obstructive infertility in Indian men.
Infertility, Male
Associations of variants in MTHFR and MTRR genes with male infertility in the Jordanian population.
Infertility, Male
Correlation between methylenetetrahydrofolate reductase gene polymorphism and oligoasthenospermia and the effects of folic acid supplementation on semen quality.
Infertility, Male
Cystathionine B-Synthase 844ins68 Gene Variant and Idiopathic Male Infertility.
Infertility, Male
Homozygous methylenetetrahydrofolate reductase C677T mutation and male infertility.
Infertility, Male
Human MTHFR-G1793A transition may be a protective mutation against male infertility: a genetic association study and in silico analysis.
Infertility, Male
Idiopathic male infertility is strongly associated with aberrant promoter methylation of methylenetetrahydrofolate reductase (MTHFR).
Infertility, Male
Influence of Methylenetetrahydrofolate Reductase C677T Gene Polymorphisms in Algerian Infertile Men with Azoospermia or Severe Oligozoospermia.
Infertility, Male
Is methylenetetrahydrofolate reductase (MTHFR) gene A1298C polymorphism related with varicocele risk?
Infertility, Male
Lack of association between genetic polymorphisms in three folate-related enzyme genes and male infertility in the Chinese population.
Infertility, Male
Lack of association of MTHFR rs1801133 polymorphism and CTCFL mutations with sperm methylation errors in infertile patients.
Infertility, Male
Methylation pattern of methylene tetrahydrofolate reductase and small nuclear ribonucleoprotein polypeptide N promoters in oligoasthenospermia: a case-control study.
Infertility, Male
Methylation patterns of methylenetetrahydrofolate reductase gene promoter in infertile males.
Infertility, Male
Methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and male infertility risk: An updated meta-analysis.
Infertility, Male
Methylenetetrahydrofolate Reductase C677T Polymorphism and Risk for Male Infertility in Asian Population.
Infertility, Male
Methylenetetrahydrofolate reductase C677T polymorphism and the risk of male infertility: a meta-analysis.
Infertility, Male
Methylenetetrahydrofolate reductase C677T polymorphism is not associated with male infertility in a South Indian population.
Infertility, Male
Methylenetetrahydrofolate reductase gene promoter hypermethylation in semen samples of infertile couples correlates with recurrent spontaneous abortion.
Infertility, Male
Methylenetetrahydrofolate reductase polymorphisms are related to male infertility in Brazilian men.
Infertility, Male
MTHFR 677C>T and 1298A>C polymorphisms and male infertility risk: a meta-analysis.
Infertility, Male
MTHFR 677C>T polymorphism increases the male infertility risk: a meta-analysis involving 26 studies.
Infertility, Male
MTHFR C677T polymorphism associates with unexplained infertile male factors.
Infertility, Male
MTHFR C677T polymorphism, GSTM1 deletion and male infertility: a possible suggestion of a gene-gene interaction?
Infertility, Male
MTHFR C677T, A1298C and MS A2756G Gene Polymorphisms and Male Infertility Risk in a Chinese Population: A Meta-Analysis.
Infertility, Male
MTHFR polymorphisms as risk for male infertility in Pakistan and its comparison with socioeconomic status in the world.
Infertility, Male
MTHFR promoter hypermethylation in testicular biopsies of patients with non-obstructive azoospermia: the role of epigenetics in male infertility.
Infertility, Male
MTHFR-Ala222Val and male infertility: a study in Iranian men, an updated meta-analysis and an in silico-analysis.
Infertility, Male
Mutation C677T in the methylenetetrahydrofolate reductase gene is associated with male infertility in an Indian population.
Infertility, Male
Prospective study of MTHFR genetic polymorphisms as a possible etiology of male infertility.
Infertility, Male
Relationship Between Genetic Polymorphisms of Methylenetetrahydrofolate Reductase (C677T, A1298C, and G1793A) as Risk Factors for Idiopathic Male Infertility.
Infertility, Male
Role of genetic mutations in folate-related enzyme genes on Male Infertility.
Infertility, Male
Significant impact of the MTHFR polymorphisms and haplotypes on male infertility risk.
Infertility, Male
Single nucleotide polymorphism C677T in the methylenetetrahydrofolate reductase gene might be a genetic risk factor for infertility for Chinese men with azoospermia or severe oligozoospermia.
Infertility, Male
Strong Association of 677 C>T Substitution in the MTHFR Gene with Male Infertility - A Study on an Indian Population and a Meta-Analysis.
Infertility, Male
The methylenetethrahydrofolate reductase (MTHFR) C677T polymorphism and male infertility in Italy.
Infertility, Male
The relationship between the C677T polymorphism of the MTHFR gene and serum levels of luteinizing hormone in males with erectile dysfunction.
Infertility, Male
The relevance of MTHFR C677T, A1298C, and MTRR A66G polymorphisms with response to male infertility in Asians: A meta-analysis.
Infertility, Male
[The effect of polymorphisms C677T and 1298 gene MTHFR on the reproductive function of men].
Inflammatory Bowel Diseases
Factor V Leiden G1691A, prothrombin G20210A, and MTHFR C677T mutations in Turkish inflammatory bowel disease patients.
Inflammatory Bowel Diseases
Factor V Leiden, prothrombin G20210A and MTHFR gene mutations in inflammatory bowel disease.
Inflammatory Bowel Diseases
Hyperhomocysteinemia and methylenetetrahydrofolate reductase 677C-->T and 1298A-->C mutations in patients with inflammatory bowel disease.
Inflammatory Bowel Diseases
Increased prevalence of methylenetetrahydrofolate reductase C677T variant in patients with inflammatory bowel disease, and its clinical implications.
Inflammatory Bowel Diseases
Methylenetetrahydrofolate reductase C677T variant in Moroccan patients with inflammatory bowel disease.
Inflammatory Bowel Diseases
Prevalence of methylenetetrahydrofolate reductase polymorphisms in young patients with inflammatory bowel disease.
Inflammatory Bowel Diseases
The association of the MTHFR C677T polymorphism with inflammatory bowel diseases in the Israeli Jewish population: An example of genetic heterogeneity.
Inflammatory Bowel Diseases
The methylenetetrahydrofolate reductase 1298 A>C polymorphism is associated with an increased risk of inflammatory bowel disease: evidence from a meta-analysis.
Insulin Resistance
Association of homocysteinemia with high concentrations of serum insulin and uric acid in Brazilian subjects with metabolic syndrome genotyped for C677T polymorphism in the methylenetetrahydrofolate reductase gene.
Insulin Resistance
Associations of MTHFR C677T polymorphism with insulin resistance, results of NURSE Study (Nursing Unacquainted Related Stress Etiologies).
Insulin Resistance
C-reactive protein, vitamin B12 and C677T polymorphism of N-5,10-methylenetetrahydrofolate reductase gene are related to insulin resistance and risk factors for metabolic syndrome in Chinese population.
Insulin Resistance
Genetic polymorphism of Methylenetetrahydrofolate reductase is associated with insulin resistance in Egyptian women with polycystic ovary syndrome.
Insulin Resistance
Interactions between genetic variants involved in the folate metabolic pathway and serum lipid, homocysteine levels on the risk of recurrent spontaneous abortion.
Insulin Resistance
Metabolic syndrome and insulin resistance in schizophrenia patients receiving antipsychotics genotyped for the methylenetetrahydrofolate reductase (MTHFR) 677C/T and 1298A/C variants.
Insulin Resistance
Methylenetetrahydrofolate reductase 677 C->T polymorphism: A link between birth weight and insulin resistance in obese adolescents.
Insulin Resistance
The Insulin-like Growth Factor-1 (G>A) and 5,10-methylenetetrahydrofolate Reductase (C677T) Gene Variants and the Serum Levels of Insulin-like Growth Factor-1, Insulin, and Homeostasis Model Assessment in Patients with Acne Vulgaris.
Insulin Resistance
[Association of C677T gene polymorphism of methylenetetrahydrofolate reductase with insulin resistance among Kirghizes].
Insulin Resistance
[Smoking enhances the decrease of adiponectin level in patients with coronary artery disease, carriers of MTHFR 677T and PON1 55M alleles].
Intellectual Disability
Lack of association between MTHFR C677T and MTHFR A1298C genetic polymorphisms and mental retardation.
Intellectual Disability
Methylenetetrahydrofolate reductase deficiency in a patient with phenotypic findings of Angelman syndrome.
Intellectual Disability
Screening for methylenetetrahydrofolate reductase C677T and A1298C polymorphisms in Indian patients with idiopathic mental retardation.
Intellectual Disability
Spine and brain malformations in a patient obligate carrier of MTHFR with autism and mental retardation.
Intermittent Claudication
Methylenetetrahydrofolate reductase polymorphism 677C>T is associated with peripheral arterial disease in type 2 diabetes.
Intracranial Aneurysm
Polymorphisms of homocysteine metabolism are associated with intracranial aneurysms.
Intracranial Arteriosclerosis
Association of Homocysteine with Aysmptomatic Intracranial and Extracranial Arterial Stenosis in Hypertension Patients.
Intracranial Hemorrhages
Associations between MTHFR gene polymorphisms and the risk of intracranial hemorrhage: Evidence from a meta-analysis.
Intracranial Thrombosis
Significance of factor V, prothrombin, MTHFR, and PAI-1 genotypes in childhood cerebral thrombosis.
Ischemic Attack, Transient
C677T MTHFR mutation and factor V Leiden mutation in patients with TIA/minor stroke: a case-control study.
Ischemic Attack, Transient
Cerebral Venous Sinus Thrombosis Presenting as Transient Ischemic Attacks in a Case With Homozygous Mutations of MTHFR A1298C and CG677T.
Ischemic Attack, Transient
Genetic and nongenetic factors influencing plasma homocysteine levels in patients with ischemic cerebrovascular disease and in healthy control subjects.
Ischemic Attack, Transient
Inherited prothrombotic risk factors in children with stroke, transient ischemic attack, or migraine.
Ischemic Attack, Transient
Sequential multiple retinal vein occlusions and transient ischemic attack in MTHFR polymorphism and protein S deficiency.
Ischemic Attack, Transient
Successful treatment of brain ischemia with supplementation therapy in a patient with hyperhomocysteinemia.
Ischemic Attack, Transient
Transient ischemic attacks in a child with post-varicella arteriopathy and MTHFR homozigotic mutation C677T.
Ischemic Attack, Transient
[Hyperhomocysteine, methylenetetrahydrofolate reductase gene, and other risk factors in ischemic stroke]
Ischemic Stroke
5,10-methylenetetrahydrofolate reductase C677T gene polymorphism and peripheral arterial disease: A meta-analysis.
Ischemic Stroke
A case of vascular parkinsonism associated with hyperhomocysteinemia and methylenetetrahydrofolate reductase gene variant (C677T).
Ischemic Stroke
A methylenetetrahydrofolate reductase gene polymorphism in ischaemic stroke and in carotid artery stenosis.
Ischemic Stroke
A plasma proteomics method reveals links between ischemic stroke and MTHFR C677T genotype.
Ischemic Stroke
A possible synergistic effect of MTHFR C677T polymorphism on homocysteine level variations increased risk for ischemic stroke.
Ischemic Stroke
A potential epigenetic marker mediating serum folate and vitamin B 12 levels contributes to the risk of ischemic stroke.
Ischemic Stroke
An analysis of methylenetetrahydrofolate reductase and glutathione S-transferase omega-1 genes as modifiers of the cerebral response to ischemia.
Ischemic Stroke
An association between methylenetetrahydrofolate reductase (C677T) polymorphism and large-artery ischemic stroke.
Ischemic Stroke
An association of 5,10-Methylenetetrahydrofolate Reductase (MTHFR) gene polymorphism and ischemic stroke.
Ischemic Stroke
Antiphospholipid antibodies in neonates with stroke--a unique entity or variant of antiphospholipid syndrome?
Ischemic Stroke
Association between factor V Leiden, prothrombin G20210A, and methylenetetrahydrofolate reductase C677T mutations and events of the arterial circulatory system: a meta-analysis of published studies.
Ischemic Stroke
Association between Glu298Asp single nucleotide polymorphism in the eNOS/MTHRF gene and blood stasis syndrome of ischemic stroke.
Ischemic Stroke
Association between high homocyst(e)ine and ischemic stroke due to large- and small-artery disease but not other etiologic subtypes of ischemic stroke.
Ischemic Stroke
Association between methylene tetrahydrofolate reductase polymorphisms and risk of ischemic stroke.
Ischemic Stroke
Association between methylenetetrahydrofolate reductase (MTHFR) polymorphism and carotid intima medial thickness progression in post ischaemic stroke patient.
Ischemic Stroke
Association between the methylenetetrahydrofolate reductase (MTHFR) gene C677T polymorphism and ischemic stroke in the Chinese population: a meta-analysis.
Ischemic Stroke
Association of acute ischemic stroke with the MTHFR C677T polymorphism but not with NOS3 gene polymorphisms in a Singapore population.
Ischemic Stroke
Association of C677T polymorphism in the methylenetetrahydrofolate reductase gene (MTHFR gene) with ischemic stroke: a meta-analysis.
Ischemic Stroke
Association of CVD candidate gene polymorphisms with ischemic stroke and cerebral hemorrhage in Chinese individuals.
Ischemic Stroke
Association of methylenetetrahydrofolate reductase (MTHFR) gene polymorphism with ischemic stroke in the Eastern Chinese Han population.
Ischemic Stroke
Association of MTHFR C677T Genotype With Ischemic Stroke Is Confined to Cerebral Small Vessel Disease Subtype.
Ischemic Stroke
Association of the methylenetetrahydrofolate reductase gene A1298C polymorphism with stroke risk based on a meta-analysis.
Ischemic Stroke
Association studies of genetic polymorphism, environmental factors and their interaction in ischemic stroke.
Ischemic Stroke
Association study between genetic polymorphisms in folate metabolism and gastric cancer susceptibility in Chinese Han population: A case-control study.
Ischemic Stroke
C677T polymorphism of the methylenetetrahydrofolate reductase gene and the risk of ischemic stroke in Polish subjects.
Ischemic Stroke
Causal relationship of susceptibility genes to ischemic stroke: comparison to ischemic heart disease and biochemical determinants.
Ischemic Stroke
Clinical and Genetic Heterogeneity in a Large Family with Pseudoxanthoma Elasticum: MTHFR and SERPINE1 Variants as Possible Disease Modifiers in Developing Ischemic Stroke.
Ischemic Stroke
Clinical Relevance of MTHFR, eNOS, ACE, and ApoE Gene Polymorphisms and Serum Vitamin Profile among Malay Patients with Ischemic Stroke.
Ischemic Stroke
Coagulation factor V G1691A, factor II G20210A and methylenetetrahydrofolate reductase C677T gene mutations do not play a major role in symptomatic neonatal arterial ischaemic stroke.
Ischemic Stroke
Common genetic markers and prediction of recurrent events after ischemic stroke in young adults.
Ischemic Stroke
Common genetic variants of homocysteine metabolism in ischemic stroke: a case-control study.
Ischemic Stroke
Common Variations in Prothrombotic Genes and Susceptibility to Ischemic Stroke in Young Patients: A Case-Control Study in Southeast Iran.
Ischemic Stroke
Connection between genetically determined blood coagulation factors and haemorheology.
Ischemic Stroke
Correlation with Platelet Parameters and Genetic Markers of Thrombophilia Panel (Factor II g.20210G>A, Factor V Leiden, MTHFR (C677T, A1298C), PAI-1, ?-Fibrinogen, Factor XIIIA (V34L), Glycoprotein IIIa (L33P)) in Ischemic Strokes.
Ischemic Stroke
Detailed analysis of gene polymorphisms associated with ischemic stroke in South asians.
Ischemic Stroke
Dose-related association of MTHFR 677T allele with risk of ischemic stroke: evidence from a cumulative meta-analysis.
Ischemic Stroke
Early-onset ischaemic stroke: analysis of 58 polymorphisms in 17 genes involved in methionine metabolism.
Ischemic Stroke
Elevated plasma homocysteine was associated with hemorrhagic and ischemic stroke, but methylenetetrahydrofolate reductase gene C677T polymorphism was a risk factor for thrombotic stroke: a Multicenter Case-Control Study in China.
Ischemic Stroke
Endothelial Dysfunction May Link Interatrial Septal Abnormalities and MTHFR-Inherited Defects to Cryptogenic Stroke Predisposition.
Ischemic Stroke
Endothelial nitric oxide synthase gene interactions and the risk of ischaemic stroke.
Ischemic Stroke
Evaluation of MTHFR C677T polymorphism in ischemic and hemorrhagic stroke patients. A case-control study in a Northern Indian population.
Ischemic Stroke
Evaluation of the interactions of common genetic mutations in stroke subtypes.
Ischemic Stroke
Evaluation of the modifying effects of unfavourable genotypes on classical clinical risk factors for ischaemic stroke.
Ischemic Stroke
Factor V Leiden, prothrombin gene G20210A variant, and methylenetetrahydrofolate reductase C677T genotype in young adults with ischemic stroke.
Ischemic Stroke
Gene polymorphisms of homocysteine metabolism-related enzymes in Chinese patients with occlusive coronary artery or cerebral vascular diseases.
Ischemic Stroke
Gene-environment interactions between methylenetetrahydrofolate reductase (MTHFR) 677C>T and metabolic syndrome for the prevalence of ischemic stroke in Koreans.
Ischemic Stroke
Gene-gene and gene-environment interplay represent specific susceptibility for different types of ischaemic stroke and leukoaraiosis.
Ischemic Stroke
Genetic analysis of the thermolabile variant of 5, 10-methylenetetrahydrofolate reductase as a risk factor for ischemic stroke.
Ischemic Stroke
Genetic polymorphisms of Chinese patients with ischemic stroke and concurrent stenoses of extracranial and intracranial vessels.
Ischemic Stroke
Genetic polymorphisms of methylenetetrahydrofolate reductase C677T and risk of ischemic stroke in a southern Chinese Hakka population.
Ischemic Stroke
Genetic Risk Factors for Arterial Ischemic Stroke in Children: A Possible MTHFR and eNOS Gene-Gene Interplay?
Ischemic Stroke
High MTHFR promoter methylation levels in men confer protection against ischemic stroke.
Ischemic Stroke
Homocysteine, MTHFR 677C-->T polymorphism, and risk of ischemic stroke: results of a meta-analysis.
Ischemic Stroke
Homocysteine, MTHFR C677 T, vitamin B12, and folate levels in Thai children with ischemic stroke: a case-control study.
Ischemic Stroke
Homozygous C677T mutation in the MTHFR gene as an independent risk factor for multiple small-artery occlusions.
Ischemic Stroke
Homozygous C677T mutation of the 5,10 methylenetetrahydrofolate reductase gene and hyperhomocysteinemia in Italian patients with a history of early-onset ischemic stroke.
Ischemic Stroke
Homozygous thermolabile variant of the methylenetetrahydrofolate reductase gene: a potential risk factor for hyperhomocysteinaemia, CVD, and stroke in childhood.
Ischemic Stroke
Hyperhomocysteinemia and hypofibrinolysis in young adults with ischemic stroke.
Ischemic Stroke
Hyperhomocysteinemia, C677T MTHFR polymorphism and ischemic stroke in Tunisian patients.
Ischemic Stroke
Influence of combined methionine synthase (MTR 2756A > G) and methylenetetrahydrofolate reductase (MTHFR 677C > T) polymorphisms to plasma homocysteine levels in Korean patients with ischemic stroke.
Ischemic Stroke
Inherited prothrombotic conditions and premature ischemic stroke: sex difference in the association with factor V Leiden.
Ischemic Stroke
Inherited thrombophilia and stratification of ischaemic stroke risk among users of oral contraceptives.
Ischemic Stroke
Inherited thrombophilia as a risk factor for the development of ischemic stroke in young adults.
Ischemic Stroke
Interaction Between Methylenetetrahydrofolate Reductase (MTHFR) Gene Polymorphisms and Environment with Susceptibility to Ischemic Stroke in Chinese Population.
Ischemic Stroke
Interaction of serum vitamin B12 and folate with MTHFR genotypes on risk of ischemic stroke.
Ischemic Stroke
Interplay between 3'-UTR polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene and the risk of ischemic stroke.
Ischemic Stroke
Is the 1298A>C polymorphism in the MTHFR gene a risk factor for arterial ischaemic stroke in children? The results of meta-analysis.
Ischemic Stroke
Ischaemic stroke following tranexamic acid in young patients carrying heterozygosity of MTHFR C677T.
Ischemic Stroke
Ischemic Stroke in a 7-Month-Old Infant With Antiphospholipid Antibody and Homozygous C677T Methylenetetrahydrofolate Reductase (MTHFR) Polymorphism.
Ischemic Stroke
Ischemic Stroke in a Patient With Atrial Tachycardia, Methylenetetrahydrofolate Reductase Mutation and New-Onset Atrial Fibrillation: Is Early Initiation of Anticoagulation Therapy Indicated?
Ischemic Stroke
Lipoprotein (a) and genetic polymorphisms of clotting factor V, prothrombin, and methylenetetrahydrofolate reductase are risk factors of spontaneous ischemic stroke in childhood.
Ischemic Stroke
Longitudinal myelitis in patient with systemic lupus erythematosus, homozygous prothrombin G20210A and heterozygous MTHFR 677T.
Ischemic Stroke
Meta-analysis of genetic studies from journals published in China of ischemic stroke in the Han Chinese population.
Ischemic Stroke
Meta-analysis of genetic studies in ischemic stroke: thirty-two genes involving approximately 18,000 cases and 58,000 controls.
Ischemic Stroke
Meta-analysis study to evaluate the association of MTHFR C677T polymorphism with risk of ischemic stroke.
Ischemic Stroke
Methylene Tetrahydrofolate Reductase (MTHFR) rs868014 Polymorphism Regulated by miR-1203 Associates with Risk and Short Term Outcome of Ischemic Stroke.
Ischemic Stroke
Methylenehydrofolate reductase (C677T) polymorphism and large artery ischemic stroke subtypes.
Ischemic Stroke
Methylenetetrahydrofolate reductase (C677T and A1298C) polymorphisms, hyperhomocysteinemia, and ischemic stroke in Tunisian patients.
Ischemic Stroke
Methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms and susceptibility to ischemic stroke: a meta-analysis.
Ischemic Stroke
Methylenetetrahydrofolate reductase C677T polymorphism in Iraqi patients with ischemic stroke.
Ischemic Stroke
Methylenetetrahydrofolate reductase deficiency alters cellular response after ischemic stroke in male mice.
Ischemic Stroke
Methylenetetrahydrofolate reductase gene A1298C polymorphism in pediatric stroke--case-control and family-based study.
Ischemic Stroke
Methylenetetrahydrofolate reductase gene A222V polymorphism and risk of ischemic stroke.
Ischemic Stroke
Methylenetetrahydrofolate reductase gene polymorphism and childhood stroke.
Ischemic Stroke
Methylenetetrahydrofolate reductase gene polymorphism and ischemic stroke in Japanese.
Ischemic Stroke
Methylenetetrahydrofolate reductase gene polymorphism and ischemic stroke: sex difference in Japanese.
Ischemic Stroke
Methylenetetrahydrofolate reductase gene polymorphism in Indian stroke patients.
Ischemic Stroke
Methylenetetrahydrofolate reductase gene polymorphisms are associated with ischemic and hemorrhagic stroke: Dual effect of MTHFR polymorphisms C677T and A1298C.
Ischemic Stroke
Migraine mediates the influence of C677T MTHFR genotypes on ischemic stroke risk with a stroke-subtype effect.
Ischemic Stroke
MTHFR (C677T) CT genotype and CT-apoE3/3 genotypic combination predisposes the risk of ischemic stroke.
Ischemic Stroke
MTHFR (C677T, A1298C), FV Leiden polymorphisms, and the prothrombin G20210A mutation in arterial ischemic stroke among young tunisian adults.
Ischemic Stroke
MTHFR C677T mutation increased the risk of Ischemic Stroke, especially in large-artery atherosclerosis in adults: an updated meta-analysis from 38 researches.
Ischemic Stroke
MTHFR C677T polymorphism and its relation to ischemic stroke in the Black Sea Turkish population.
Ischemic Stroke
MTHFR Gene Polymorphisms Prevalence and Cardiovascular Risk Factors Involved in Cardioembolic Stroke Type and Severity.
Ischemic Stroke
Mutations and Polymorphisms in Genes Affecting Hemostasis Proteins and Homocysteine Metabolism in Children with Arterial Ischemic Stroke.
Ischemic Stroke
Na VPA-induced acute ischemic stroke in an epileptic patient with methylenetetrahydrofolate reductase gene polymorphism.
Ischemic Stroke
Ocular vascular thrombotic events: a diagnostic window to familial thrombophilia (compound factor v leiden and prothrombin gene heterozygosity) and thrombosis.
Ischemic Stroke
Plasma homocysteine concentration, C677T MTHFR genotype, and 844ins68bp CBS genotype in young adults with spontaneous cervical artery dissection and atherothrombotic stroke.
Ischemic Stroke
Plasma total homocysteine and the methylenetetrahydrofolate reductase 677C>T polymorphism do not contribute to the distribution of cervico-cerebral atherosclerosis in ischaemic stroke patients.
Ischemic Stroke
Polymorphism in the methylenetetrahydrofolate reductase (C677T) gene and homocysteine levels: a comparison in Brazilian patients with coronary arterial disease, ischemic stroke and peripheral arterial obstructive disease.
Ischemic Stroke
Polymorphism of the methylenetetrahydrofolate reductase gene association with homocysteine and ischemic stroke in type 2 diabetes.
Ischemic Stroke
Polymorphisms of MTHFR, eNOS, ACE, AGT, ApoE, PON1, PDE4D, and Ischemic Stroke: Meta-Analysis.
Ischemic Stroke
Prevalence of Thrombophilic Mutations and ACE ID Polymorphism in Turkish Ischemic Stroke Patients.
Ischemic Stroke
Prospective study of first stroke in relation to plasma homocysteine and MTHFR 677C>T and 1298A>C genotypes and haplotypes - evidence for an association with hemorrhagic stroke.
Ischemic Stroke
Prothrombotic conditions, oral contraceptives, and the risk of ischemic stroke.
Ischemic Stroke
Recurrent ischemic strokes in a young celiac woman with MTHFR gene mutation.
Ischemic Stroke
Recurrent thromboembolism in infants and children suffering from symptomatic neonatal arterial stroke: a prospective follow-up study.
Ischemic Stroke
Relationship between methylenetetrahydrofolate reductase (MTHFR) gene (A1298C) polymorphism with the risk of stroke: A systematic review and meta-analysis.
Ischemic Stroke
Role of a common mutation in the homocysteine regulatory enzyme methylenetetrahydrofolate reductase in ischemic stroke.
Ischemic Stroke
Sonographic evaluation of atherosclerosis burden in carotid arteries of ischemic stroke patients and its relation to paraoxonase 1 and 2, MTHFR and AT1R genetic variants.
Ischemic Stroke
Synergistic effect of MTHFR C677T and F2 G20210A polymorphisms on ischemic stroke.
Ischemic Stroke
Synergistic Effect of the MTHFR C677T and EPHX2 G860A Polymorphism on the Increased Risk of Ischemic Stroke in Chinese Type 2 Diabetic Patients.
Ischemic Stroke
Tagging Functional Polymorphism in 3' Untranslated Region of Methylene Tetrahydrofolate Reductase and Risk of Ischemic Stroke.
Ischemic Stroke
Tagging SNPs in the MTHFR gene and risk of ischemic stroke in a Chinese population.
Ischemic Stroke
The APOE E4 Allele Confers Increased Risk of Ischemic Stroke Among Greek Carriers.
Ischemic Stroke
The association of MTHFR C677T variant with increased risk of ischemic stroke in the elderly population: a meta-analysis of observational studies.
Ischemic Stroke
The C677T polymorphism of the methylenetetrahydrofolate reductase gene is associated with idiopathic ischemic stroke in the young Mexican-Mestizo population.
Ischemic Stroke
The combination of homozygous MTHFR 677T and angiotensin II type-1 receptor 1166C variants confers the risk of small-vessel-associated ischemic stroke.
Ischemic Stroke
The effect of polymorphisms of MTHFR C677T, A1298C, MS A2756G and CBS 844ins68bp on plasma total homocysteine level and the risk of ischemic stroke in Thai children.
Ischemic Stroke
The factor V Leiden, prothrombin gene 20210GA, methylenetetrahydrofolate reductase 677CT and platelet glycoprotein IIIa 1565TC mutations in patients with acute ischemic stroke and atrial fibrillation.
Ischemic Stroke
The methylenetetrahydrofolate reductase (MTHFR) 677C-->T mutation and cardiovascular risk--A case of ischemic stroke and acute myocardial infarction.
Ischemic Stroke
The Methylenetetrahydrofolate Reductase C677T (rs1801133) and Apolipoprotein A5-1131T>C (rs662799) Polymorphisms, and Anemia Are Independent Risk Factors for Ischemic Stroke.
Ischemic Stroke
The methylenetetrahydrofolate reductase gene C677T mutant and ischemic stroke in sickle cell disease.
Ischemic Stroke
The Methylenetetrahydrofolate Reductase Polymorphism (MTHFR c.677C>T) and Elevated Plasma Homocysteine Levels in a U.S. Pediatric Population with Incident Thromboembolism.
Ischemic Stroke
The Relationship of Methylenetetrahydrofolate Reductase Gene C677T Polymorphism and Ischemic Stroke in Chinese Han Population.
Ischemic Stroke
The role of genetic risk factors in arterial ischemic stroke in pediatric and adult patients: a critical review.
Ischemic Stroke
The Role of Polymorphism Gen Methylene Tetra Hydrofolate Reductase (MTHFR) C677T in Ischaemic Stroke Patients with and Without Hypertension.
Ischemic Stroke
The T allele of the 677C>T polymorphism of methylenetetrahydrofolate reductase gene is associated with an increased risk of ischemic stroke in Polish children.
Ischemic Stroke
The TT genotype of methylenetetrahydrofolate reductase 677C>T polymorphism increases the susceptibility to pediatric ischemic stroke: meta-analysis of the 822 cases and 1,552 controls.
Ischemic Stroke
The U-shaped relationship between serum methylene tetrahydrofolate reductase and large-artery atherosclerotic stroke.
Ischemic Stroke
TT genotype of the methylenetetrahydrofolate reductase C677T polymorphism is an important determinant for homocysteine levels in multi-ethnic Malaysian ischaemic stroke patients.
Ischemic Stroke
[A case-control study on the relationship between stroke and plasma homocysteine level and the mutation of MTHFR gene.]
Ischemic Stroke
[A clinical and genetic analysis of risk factors for the development of acute and chronic cerebral ischemia].
Ischemic Stroke
[A comparative analysis of allele frequencies of rs1801133 and rs1801131 of MTHFR in patients with stroke and healthy people from the Moscow region].
Ischemic Stroke
[A role of genetic factors and related disorder of the folate cycle in ischemic stroke].
Ischemic Stroke
[Association study of renin-angiotensin system genes and hemostasis system genes with ischemic stroke among Russians of Central Russia].
Ischemic Stroke
[Genetic mutations of homocysteine metabolism related enzymes in patients with ischemic stroke.]
Ischemic Stroke
[Hyperhomocysteine, methylenetetrahydrofolate reductase gene, and other risk factors in ischemic stroke]
Ischemic Stroke
[Interactions between the MTHFR C677T and MTHFR A1298C mutations in ischaemic stroke]
Ischemic Stroke
[Mutations of genes associated with thromboses in ischemic stroke in patients with primary antiphospholipid syndrome]
Ischemic Stroke
[Prevalence of methylenetetrahydrofolate reductase C677T mutation among patients with acute ischemic cerebrovascular disease in Aragon]
Ischemic Stroke
[Relationship between methylenetetrahydrofolate reductase gene C677T polymorphism and susceptibility of ischemic stroke: a meta-analysis].
Ischemic Stroke
[Relationship between methylenetrahydrofolate reductase gene and ischemic stroke]
Ischemic Stroke
[Role of methyltetrahydrofolate reductase (MTHFR) gene polymorphism in the development of ischemic stroke in the dwellers of the Kyrgyz Republic].
Ischemic Stroke
[Study on relationship between constitution and syndrome of MMP-9, IL-6 and MTHFR gene in patients with ischemic stroke].
isovaleryl-coa dehydrogenase deficiency
Epidemiology of rare diseases detected by newborn screening in the Czech Republic.
Joint Diseases
Genetic biomarkers related to hemarthrosis, inflammation, and cartilage structure in pediatric patients with hemophilic arthropathy.
Kidney Diseases
Methionine synthase reductase MTRR 66A > G has no effect on total homocysteine, folate, and Vitamin B12 concentrations in renal transplant patients.
Kidney Diseases
Methylenetetrahydrofolate reductase (MTHFR) polymorphism A1298C (Glu429Ala) predicts decline in renal function over time in the African-American Study of Kidney Disease and Hypertension (AASK) Trial and Veterans Affairs Hypertension Cohort (VAHC).
Kidney Failure, Chronic
An MTHFR variant, homocysteine, and cardiovascular comorbidity in renal disease.
Kidney Failure, Chronic
An unusually high plasma concentration of homocysteine resulting from a combination of so-called "secondary" etiologies.
Kidney Failure, Chronic
Cerebral vascular complication and hyperhomocysteinemia in a cystinotic uremic child.
Kidney Failure, Chronic
Contribution of GSTM1, GSTT1, and MTHFR polymorphisms to end-stage renal disease of unknown etiology in Mexicans.
Kidney Failure, Chronic
Correlations of MTHFR 677C>T polymorphism with cardiovascular disease in patients with end-stage renal disease: a meta-analysis.
Kidney Failure, Chronic
Decisive evidence corroborates a null relationship between MTHFR C677T and chronic kidney disease: A case-control study and a meta-analysis.
Kidney Failure, Chronic
DNA methylation status of the methylenetetrahydrofolate reductase gene promoter in peripheral blood of end-stage renal disease patients.
Kidney Failure, Chronic
Effect of MTHFR C677T genotype on survival in type 2 diabetes patients with end-stage diabetic nephropathy.
Kidney Failure, Chronic
Effect of the MTHFR C677T and A1298C polymorphisms on survival in patients with advanced CKD and ESRD: a prospective study.
Kidney Failure, Chronic
Hyperhomocysteinemia is related to residual glomerular filtration and folate, but not to methylenetetrahydrofolate-reductase and methionine synthase polymorphisms, in supplemented end-stage renal disease patients undergoing hemodialysis.
Kidney Failure, Chronic
Hyperhomocysteinemia, diabetes mellitus, and carotid atherosclerosis independently increase atherosclerotic vascular disease outcome in Japanese patients with end-stage renal disease.
Kidney Failure, Chronic
Influence of 5,10-methylenetetrahydrofolate reductase gene polymorphism on plasma homocysteine concentration in patients with end-stage renal disease.
Kidney Failure, Chronic
Methylenetetrahydrofolate reductase gene C677T polymorphism, plasma homocysteine and folate in end-stage renal disease dialysis and non-dialysis patients.
Kidney Failure, Chronic
Methylenetetrahydrofolate reductase gene polymorphisms in essential hypertension relation: with the development of hypertensive end-stage renal disease.
Kidney Failure, Chronic
MTHFR A1298C polymorphism is associated with cardiovascular risk in end stage renal disease in North Indians.
Kidney Failure, Chronic
MTHFR and HFE, but not preproghrelin and LBP, polymorphisms as risk factors for all-cause end-stage renal disease development.
Kidney Failure, Chronic
Mutation (677 C to T) in the methylenetetrahydrofolate reductase gene aggravates hyperhomocysteinemia in hemodialysis patients.
Kidney Failure, Chronic
Phenotypic and genotypic risk factors for cardiovascular events in an incident dialysis cohort.
Kidney Failure, Chronic
Polymorphism in methylenetetrahydrofolate reductase gene: its impact on plasma homocysteine levels and carotid atherosclerosis in ESRD patients receiving hemodialysis.
Kidney Failure, Chronic
Polymorphism in methylenetetrahydrofolate reductase, plasminogen activator inhibitor-1, and apolipoprotein E in hemodialysis patients.
Kidney Failure, Chronic
Prediction of susceptible biomarkers for end stage renal disease among North Indians.
Kidney Failure, Chronic
The C677T methylenetetrahydrofolate reductase gene mutation does not influence cardiovascular risk in the dialysis population: results of a multicentre prospective study.
Kidney Failure, Chronic
The MTHFR 677TT and 677CT/1298AC genotypes in Cypriot patients may be predisposing to hypertensive nephrosclerosis and chronic renal failure.
Kidney Neoplasms
Comprehensive evaluation of one-carbon metabolism pathway gene variants and renal cell cancer risk.
Klinefelter Syndrome
Severe arterial thrombophilia associated with a homozygous MTHFR gene mutation (A1298C) in a young man with Klinefelter syndrome.
Laryngeal Neoplasms
Alterations in the expression pattern of MTHFR, DHFR, TYMS, and SLC19A1 genes after treatment of laryngeal cancer cells with high and low doses of methotrexate.
Laryngeal Neoplasms
Association of dietary intake of folate and MTHFR genotype with breast cancer risk.
Laryngeal Neoplasms
Polymorphic variants of folate metabolism genes and the risk of laryngeal cancer.
Lateral Sinus Thrombosis
Bilateral transverse sinus thrombosis secondary to a homozygous C677T MTHFR gene mutation.
Lateral Sinus Thrombosis
[Acute cerebral sinus-thrombosis due to polyangiitis overlap syndrome with granulomatosis with polyangiitis (Wegener's granulomatosis) and eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome)].
Legg-Calve-Perthes Disease
Association of MTHFR and TNF-? genes polymorphisms with susceptibility to Legg-Calve-Perthes disease in Iranian children: A case-control study.
Legg-Calve-Perthes Disease
Meta-analysis of hypercoagulability genetic polymorphisms in perthes disease.
Legg-Calve-Perthes Disease
PlA2 Polymorphism of Platelet Glycoprotein IIb/IIIa and C677T Polymorphism of Methylenetetrahydrofolate Reductase (MTHFR), but Not Factor V Leiden and Prothrombin G20210A Polymorphisms, Are Associated with More Severe Forms of Legg-Calvé-Perthes Disease.
Leiomyoma
Correlation Analysis Between MTHFR C677T Polymorphism and Uterine Fibroids: A Retrospective Cohort Study.
Lemierre Syndrome
Lemierre's syndrome with double heterozygote status in the methylenetetrahydrofolate reductase gene.
Lens Subluxation
CBS mutations and MTFHR SNPs causative of hyperhomocysteinemia in Pakistani children.
Lens Subluxation
Homocysteinemia due to MTHFR deficiency in a young adult presenting with bilateral lens subluxations.
Leukemia
5,10-Methylenetetrahydrofolate reductase polymorphisms and leukemia risk: a HuGE minireview.
Leukemia
A duplex polymerase chain reaction-restriction fragment length polymorphism for rapid screening of methylenetetrahydrofolate reductase gene variants: Genotyping in acute leukemia.
Leukemia
Association between the MTHFR A1298C polymorphism and increased risk of acute myeloid leukemia in Brazilian children.
Leukemia
Association of drug metabolism gene polymorphisms with toxicities, graft-versus-host disease and survival after HLA-identical sibling hematopoietic stem cell transplantation for patients with leukemia.
Leukemia
Association of methylenetetrahydrofolate reductase C677T-A1298C polymorphisms with risk for esophageal adenocarcinoma, Barrett's esophagus, and reflux esophagitis.
Leukemia
Association of the 5,10-methylenetetrahydrofolate reductase (MTHFR C677T and A1298C) polymorphisms in Korean patients with adult acute lymphoblastic leukemia.
Leukemia
Characterization of MTHFR, GSTM1, GSTT1, GSTP1, and CYP1A1 genotypes in childhood acute leukemia.
Leukemia
Deregulation of folate pathway gene expression correlates with poor prognosis in acute leukemia.
Leukemia
Folic acid supplementation, MTHFR and MTRR polymorphisms, and the risk of childhood leukemia: the ESCALE study (SFCE).
Leukemia
Genotyping of the MTHFR gene polymorphism, C677T in patients with leukemia by melting curve analysis.
Leukemia
Maternal and offspring genetic variants of AKR1C3 and the risk of childhood leukemia.
Leukemia
Meta-prediction of MTHFR gene polymorphism-mutations, air pollution, and risks of leukemia among world populations.
Leukemia
Methotrexate-induced mucositis in acute leukemia patients is not associated with the MTHFR 677T allele in Mexico.
Leukemia
Methylenetetrahydrofolate reductase (MTHFR) C677T and thymidylate synthase promoter (TSER) polymorphisms in Indonesian children with and without leukemia.
Leukemia
Methylenetetrahydrofolate reductase (MTHFR) polymorphisms and risk of molecularly defined subtypes of childhood acute leukemia.
Leukemia
Methylenetetrahydrofolate reductase and glutathione s-tranferase gene polymorphisms in secondary mixed phenotype acute leukemia: a case report.
Leukemia
Methylenetetrahydrofolate reductase gene polymorphisms and lung cancer: a meta-analysis.
Leukemia
Methylenetetrahydrofolate reductase gene polymorphisms: association with risk for pediatric acute lymphoblastic leukemia in north Indians.
Leukemia
MTHFR 677CC/1298CC genotypes are highly associated with chronic myelogenous leukemia: a case-control study in Korea.
Leukemia
MTHFR C677T polymorphisms and childhood acute lymphoblastic leukemia: A meta-analysis.
Leukemia
MTHFR Gene Polymorphisms and the Risk of Acute Lymphoblastic Leukemia in Adults and Children: A Case Control Study in India.
Leukemia
MTHFR single nucleotide polymorphism associated with working memory in pediatric medulloblastoma survivors.
Leukemia
No evidence of association of methylenetetrahydrofolate reductase polymorphism with occurrence of second neoplasms after treatment of childhood leukemia.
Leukemia
Polymorphisms in the methylenetetrahydrofolate reductase gene are associated with susceptibility to acute leukemia in adults.
Leukemia
Polymorphisms involved in folate metabolism pathways and the risk of the development of childhood acute leukemia.
Leukemia
Polymorphisms of 5,10-methylenetetrahydrofolate reductase and thymidylate synthase, dietary folate intake, and the risk of leukemia in adults.
Leukemia
Preponderance of methylenetetrahydrofolate reductase C677T homozygosity among leukemia patients intolerant to methotrexate.
Leukemia
Role of MTHFR (677, 1298) haplotype in the risk of developing secondary leukemia after treatment of breast cancer and hematological malignancies.
Leukemia
Role of MTHFR genetic polymorphisms in the susceptibility to childhood acute lymphoblastic leukemia.
Leukemia
The association of methylenetetrahydrofolate reductase genotypes with the risk of childhood leukemia in Taiwan.
Leukemia
The frequent 5,10-methylenetetrahydrofolate reductase C677T polymorphism is associated with a common haplotype in whites, Japanese, and Africans.
Leukemia
The potential effect of gender in combination with common genetic polymorphisms of drug-metabolizing enzymes on the risk of developing acute leukemia.
Leukemia
The role of methylenetetrahydrofolate reductase in acute lymphoblastic leukemia in a Brazilian mixed population.
Leukemia
Thiopurine S-Methyltransferase and Methylenetetrahydrofolate Reductase Polymorphisms in Leukemia.
Leukemia
[Detection of Single Nucleotide Polymorphisms of mthfr and dpyd Genes in Leukemia Cell Lines K562 and K562/A02.]
Leukemia, Lymphocytic, Chronic, B-Cell
Association of MTHFR C677T and A1298C Polymorphisms with Susceptibility to Chronic Lymphocytic Leukemia: A Systematic Review and Meta-Analysis.
Leukemia, Lymphocytic, Chronic, B-Cell
Methylenetetrahydrofolate reductase (MTHFR) gene 677C>T and 1298A>C polymorphisms are associated with differential apoptosis of leukemic B cells in vitro and disease progression in chronic lymphocytic leukemia.
Leukemia, Lymphocytic, Chronic, B-Cell
MTHFR polymorphisms and risk of chronic lymphocytic leukemia.
Leukemia, Lymphocytic, Chronic, B-Cell
The influence of MTHFR C677T polymorphism in chronic lymphocytic leukemia.
Leukemia, Lymphoid
5,10-Methylenetetrahydrofolate reductase polymorphisms and leukemia risk: a HuGE minireview.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Association between methylene tetrahydrofolate reductase and glutathione S-transferase M1 gene polymorphisms and chronic myeloid leukemia in a Brazilian population.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Association between methylenetetrahydrofolate reductase polymorphism C677T and risk of chronic myeloid leukemia in Serbian population.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Chronic Myeloid Leukemia with b3a3 (e14a3) Fusion: A Rare BCR/ABL Rearrangement Presenting with Thrombocytosis - Does MTHFR Polymorphism Matter.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Genotyping of the MTHFR gene polymorphism, C677T in patients with leukemia by melting curve analysis.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Haplotype analysis of the C677T and A1298C polymorphisms of MTHFR and susceptibility to chronic myeloid leukemia.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Meta-prediction of MTHFR gene polymorphism-mutations, air pollution, and risks of leukemia among world populations.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Methylenetetrahydrofolate reductase and thymidylate synthase genotypes and risk of acute graft-versus-host disease following hematopoietic cell transplantation for chronic myelogenous leukemia.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Methylenetetrahydrofolate Reductase Gene C677T and A1298C Polymorphic Sequence Variations Influences the Susceptibility to Chronic Myeloid Leukemia in Kashmiri Population.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Methylenetetrahydrofolate reductase gene polymorphism and risk of chronic myelogenous leukemia: a meta-analysis.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Methylenetetrahydrofolate reductase gene polymorphisms contribute to acute myeloid leukemia and chronic myeloid leukemia susceptibilities: appraisal of a recent meta-analysis.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Methylenetetrahydrofolate reductase gene polymorphisms contribute to acute myeloid leukemia and chronic myeloid leukemia susceptibilities: evidence from meta-analyses.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Methylenetetrahydrofolate reductase genotype affects risk of relapse after hematopoietic cell transplantation for chronic myelogenous leukemia.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
MTHFR 677CC/1298CC genotypes are highly associated with chronic myelogenous leukemia: a case-control study in Korea.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
MTHFR A1298C and C677T gene polymorphisms and susceptibility to chronic myeloid leukemia in Egypt.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
MTHFR genetic polymorphisms may contribute to the risk of chronic myelogenous leukemia in adults: a meta-analysis of 12 genetic association studies.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
The methylenetetrahydrofolate reductase (MTHFR) 677 C>T polymorphism increases the risk of developing chronic myeloid leukemia-a case-control study.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
[PROVISIONAL] The differential effects of the methylenetetrahydrofolate reductase polymorphisms (C677T and A1298C) on hematological malignancies among Latinos: a meta-analysis.
Leukemia, Myeloid
Genotyping of the MTHFR gene polymorphism, C677T in patients with leukemia by melting curve analysis.
Leukemia, Myeloid, Acute
Association between MTHFR polymorphisms and acute myeloid leukemia risk: a meta-analysis.
Leukemia, Myeloid, Acute
Association between the MTHFR A1298C polymorphism and increased risk of acute myeloid leukemia in Brazilian children.
Leukemia, Myeloid, Acute
Characterization of MTHFR, GSTM1, GSTT1, GSTP1, and CYP1A1 genotypes in childhood acute leukemia.
Leukemia, Myeloid, Acute
Genetic variation in the folate metabolic pathway and risk of childhood leukemia.
Leukemia, Myeloid, Acute
Meta-prediction of MTHFR gene polymorphism-mutations, air pollution, and risks of leukemia among world populations.
Leukemia, Myeloid, Acute
Methylenetetrahydrofolate reductase 677 C> T polymorphism is associated with acute myeloid leukemia.
Leukemia, Myeloid, Acute
Methylenetetrahydrofolate reductase gene polymorphisms contribute to acute myeloid leukemia and chronic myeloid leukemia susceptibilities: appraisal of a recent meta-analysis.
Leukemia, Myeloid, Acute
Methylenetetrahydrofolate reductase gene polymorphisms contribute to acute myeloid leukemia and chronic myeloid leukemia susceptibilities: evidence from meta-analyses.
Leukemia, Myeloid, Acute
MTHFR 677C-->T and 1298A-->C polymorphisms in children with Down syndrome and acute myeloid leukemia in Brazil.
Leukemia, Myeloid, Acute
Polymorphisms in the methylenetetrahydrofolate reductase gene (MTHFR) are associated with susceptibility to adult acute myeloid leukemia in a Chinese population.
Leukemia, Myeloid, Acute
Polymorphisms in the methylenetetrahydrofolate reductase gene are associated with susceptibility to acute leukemia in adults.
Leukemia, Myeloid, Acute
Polymorphisms of 5,10-methylenetetrahydrofolate reductase and thymidylate synthase, dietary folate intake, and the risk of leukemia in adults.
Leukemia, Myeloid, Acute
The potential effect of gender in combination with common genetic polymorphisms of drug-metabolizing enzymes on the risk of developing acute leukemia.
Leukemia, Myeloid, Acute
[A new method for 5, 10-methylenetetrahydrofolate reductase single nucleotide polymorphisms genotyping used to study susceptibility of hematological malignancy]
Leukemia, Myeloid, Acute
[Association of single nucleotide polymorphism of methylenetetrahydrofolate reductase gene with susceptibility to acute leukemia].
Leukemia, Myeloid, Acute
[PROVISIONAL] The differential effects of the methylenetetrahydrofolate reductase polymorphisms (C677T and A1298C) on hematological malignancies among Latinos: a meta-analysis.
Leukoencephalopathies
Acute leukoencephalopathy possibly induced by phenytoin intoxication in an adult patient with methylenetetrahydrofolate reductase deficiency.
Leukoencephalopathies
Intermittent encephalopathy, reversible nerve conduction slowing, and MRI evidence of cerebral white matter disease in methylenetetrahydrofolate reductase deficiency.
Leukoencephalopathies
Methylenetetrahydrofolate Reductase Deficiency as a Cause of Treatable Adult-onset Leukoencephalopathy and Myelopathy.
Leukoencephalopathies
MTHFR Gene Mutations Correlate with White Matter Disease Burden and Predict Cerebrovascular Disease and Dementia.
Leukoencephalopathies
Posterior-predominant leukoencephalopathy which was caused by methylenetetrahydrofolate reductase deficiency and successfully treated with folic acid.
Leukoencephalopathies
Rapidly progressive psychotic symptoms triggered by infection in a patient with methylenetetrahydrofolate reductase deficiency: a case report.
Leukoencephalopathies
Reversible leukoencephalopathy and cerebral atrophy in Homocystinuria due to MTHFR deficiency: A treatable metabolic disorder.
Leukopenia
Correlation Between Methylenetetrahydrofolate Reductase (MTHFR) C677T Polymorphisms and Pemetrexed Chemotherapy Efficacy/Toxicity in Non-Squamous Non-Small Cell Lung Cancer.
Leukopenia
Gene polymorphisms in folate metabolizing enzymes in adult acute lymphoblastic leukemia: effects on methotrexate-related toxicity and survival.
Leukopenia
Gene-Gene Interactions of Gemcitabine Metabolizing-Enzyme Genes hCNT3 and WEE1 for Preventing Severe Gemcitabine-Induced Hematological Toxicity.
Leukopenia
High dose methotrexate treatment in childhood ALL: pilot study on the impact of the MTHFR 677C>T and 1298A>C polymorphisms on MTX-related toxicity.
Leukopenia
Methotrexate-induced toxicity pharmacogenetics: an umbrella review of systematic reviews and meta-analyses.
Leukopenia
Methylenetetrahydrofolate reductase gene haplotypes affect toxicity during maintenance therapy for childhood acute lymphoblastic leukemia in Japanese patients.
Leukopenia
Pharmacogenetic studies in children with acute lymphoblastic leukemia in Argentina.
Lichen Planus
Studying the association between methylenetetrahydrofolate reductase (MTHFR) 677 gene polymorphism, cardiovascular risk and lichen planus.
Lichen Planus, Oral
Association of vdr, cyp27b1, cyp24a1 and mthfr gene polymorphisms with oral lichen planus risk.
Livedo Reticularis
Cerebral Venous Thrombosis and Livedo Reticularis in a Case with MTHFR 677TT Homozygote.
Livedoid Vasculopathy
Livedoid vasculopathy and hypercoagulability in a patient with primary Sjögren's syndrome.
Livedoid Vasculopathy
Livedoid vasculopathy associated with combined prothrombin G20210A and factor V (Leiden) heterozygosity and MTHFR C677T homozygosity.
Livedoid Vasculopathy
Livedoid vasculopathy in a patient with lupus anticoagulant and MTHFR mutation: treatment with low-molecular-weight heparin.
Livedoid Vasculopathy
Polymorphisms of MTHFR gene associated with livedoid vasculopathy in Taiwanese population.
Liver Cirrhosis
Hyperhomocysteinaemia in chronic liver diseases: role of disease stage, vitamin status and methylenetetrahydrofolate reductase genetics.
Liver Cirrhosis
Hyperhomocysteinemia and MTHFR C677T polymorphism in patients with portal vein thrombosis complicating liver cirrhosis.
Liver Cirrhosis
Hyperhomocysteinemia and the MTHFR C677T polymorphism promote steatosis and fibrosis in chronic hepatitis C patients.
Liver Cirrhosis
Methylenetetrahydrofolate reductase C677T polymorphism and liver fibrosis progression in patients with recurrent hepatitis C.
Liver Cirrhosis
Methylenetetrahydrofolate reductase homozygosis and low-density lipoproteins in patients with genotype 1 chronic hepatitis C.
Liver Cirrhosis
MTHFR C677T mutations in liver cirrhosis with and without portal vein thrombosis.
Liver Cirrhosis
MTHFR C677T polymorphism and risk of HCC in patients with liver cirrhosis: role of male gender and alcohol consumption.
Liver Cirrhosis
MTHFR C677TT, PAI1 4G-4G, V Leiden Q506, and prothrombin G20210A in hepatocellular carcinoma with and without portal vein thrombosis.
Liver Cirrhosis
MTHFR rs1801133 Polymorphism Is Associated With Liver Fibrosis Progression in Chronic Hepatitis C: A Retrospective Study.
Liver Cirrhosis
PAI-1 4G-4G and MTHFR 677TT in non-hepatitis C virus/hepatitis B virus-related liver cirrhosis.
Liver Cirrhosis
Portal vein thrombosis in Egyptian patients with liver cirrhosis: Role of methylenetetrahydrofolate reductase C677T gene mutation.
Liver Cirrhosis
Possible Association Between the Methylenetetrahydrofolate Reductase Gene C677T Polymorphism and Preexisting Portal Vein Thrombosis in Liver Transplant Recipients.
Liver Cirrhosis
Thrombophilic genetic factors PAI-1 4G-4G and MTHFR 677TT as risk factors of alcohol, cryptogenic liver cirrhosis and portal vein thrombosis, in a Caucasian population.
Liver Cirrhosis
[Mathematic Model for Prediction of Liver Fibrosis Progression Rate in Patients with Chronic Hepatitis C Based on Combination of Genomic Markers].
Liver Cirrhosis
[The relationship between the plasma homocysteine level and the polymorphism of MTHFR gene C667T in liver cirrhosis]
Liver Cirrhosis, Alcoholic
The MTHFR 677C > T polymorphism is associated with an increased risk of hepatocellular carcinoma in patients with alcoholic cirrhosis.
Liver Diseases
Alanine amino transferase concentrations are linked to folate intakes and methylenetetrahydrofolate reductase polymorphism in obese adolescent girls.
Liver Diseases
Associations between Methylenetetrahydrofolate Reductase (MTHFR) Polymorphisms and Non-Alcoholic Fatty Liver Disease (NAFLD) Risk: A Meta-Analysis.
Liver Diseases
Hyperhomocysteinaemia in chronic liver diseases: role of disease stage, vitamin status and methylenetetrahydrofolate reductase genetics.
Liver Diseases
Methylenetetrahydrofolate reductase C677T mutation and nonalcoholic fatty liver disease.
Liver Diseases
Methylenetetrahydrofolate Reductase Gene Polymorphism and Serum Homocysteine Levels in Nonalcoholic Fatty Liver Disease.
Liver Diseases
Mild Methylenetetrahydrofolate Reductase Deficiency Alters Inflammatory and Lipid Pathways in Liver.
Liver Diseases
MTHFR C677T polymorphism and risk of HCC in patients with liver cirrhosis: role of male gender and alcohol consumption.
Liver Diseases
MTHFR rs1801133 Polymorphism Is Associated With Liver Fibrosis Progression in Chronic Hepatitis C: A Retrospective Study.
Liver Diseases
Non-alcoholic fatty liver disease (NAFLD) and MTHFR 1298A > C gene polymorphism.
Liver Diseases
The methylenetetrahydrofolate reductase genotype 677CT and non-alcoholic fatty liver disease have a synergistic effect on the increasing homocysteine levels in subjects from Chongqing, China.
Liver Diseases
[C677T AND A1298C ALLELE POLYMORPHISM GENE OF METHYLENETETRAHYDRAFOLATEREDUCTASE IN PATIENTS WITH NONALCOHOLIC FATTY LIVER DISEASE AND TYPE 2 DIABETES].
Liver Diseases, Alcoholic
MTHFR C677T polymorphism and risk of HCC in patients with liver cirrhosis: role of male gender and alcohol consumption.
Liver Neoplasms
Association between the MTHFR C677T polymorphism and risk of cancer: evidence from 446 case-control studies.
Liver Neoplasms
Associations between MTHFR Ala222Val polymorphism and risks of hepatitis and hepatitis-related liver cancer: a meta-analysis.
Liver Neoplasms
Folate metabolism-related gene polymorphisms and susceptibility to primary liver cancer in North China.
Liver Neoplasms
Metabolomic study of the intervention effects of Shuihonghuazi Formula, a Traditional Chinese Medicinal formulae, on hepatocellular carcinoma (HCC) rats using performance HPLC/ESI-TOF-MS.
Liver Neoplasms
Methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms and the risk of primary hepatocellular carcinoma (HCC) in a Chinese population.
Liver Neoplasms
Quantitative assessment of the association between MTHFR rs1801131 polymorphism and risk of liver cancer.
Liver Neoplasms
Single nucleotide polymorphisms of one-carbon metabolism and cancers of the esophagus, stomach, and liver in a Chinese population.
Liver Neoplasms
The RFC1 80G>A, among Common One-Carbon Polymorphisms, Relates to Survival Rate According to DNA Global Methylation in Primary Liver Cancers.
long-chain acyl-coa dehydrogenase deficiency
Epidemiology of rare diseases detected by newborn screening in the Czech Republic.
long-chain-3-hydroxyacyl-coa dehydrogenase deficiency
Epidemiology of rare diseases detected by newborn screening in the Czech Republic.
Lung Neoplasms
A methylenetetrahydrofolate reductase polymorphism is associated with expression of p16 in human lung cancer.
Lung Neoplasms
A single-nucleotide polymorphism in the MTHFR (methylene tetrahydrofolate reductase) gene is associated with risk of radiation pneumonitis in lung cancer patients treated with thoracic radiation therapy.
Lung Neoplasms
Allele and Genotype Frequencies of the Polymorphic Methylenetetrahydrofolate Reductase and Lung Cancer in ther Jordanian Population: a Case Control Study.
Lung Neoplasms
Association between methylenetetrahydrofolate reductase (MTHFR) polymorphisms and lung cancer risk in Chinese people: An updated meta-analysis.
Lung Neoplasms
Association of deep venous thrombosis with prothrombotic gene polymorphism identified in lung cancer cases.
Lung Neoplasms
Association of polymorphisms in one-carbon metabolizing genes and lung cancer risk: a case-control study in Chinese population.
Lung Neoplasms
Combined Effect of MTHFR C677T and PAI-1 4G/5G Polymorphisms on the Risk of Venous Thromboembolism in Chinese Lung Cancer Patients.
Lung Neoplasms
Correlation Between Methylenetetrahydrofolate Reductase (MTHFR) C677T Polymorphisms and Pemetrexed Chemotherapy Efficacy/Toxicity in Non-Squamous Non-Small Cell Lung Cancer.
Lung Neoplasms
Development of lung cancer before the age of 50: the role of xenobiotic metabolizing genes.
Lung Neoplasms
Effect of the methylenetetrahydrofolate reductase C677T polymorphism on patients with cisplatin/gemcitabine-treated stage IV non-small-cell lung cancer.
Lung Neoplasms
Folate pathway gene MTHFR C677T polymorphism and risk of lung cancer in Asian populations.
Lung Neoplasms
Folate-related genes and the risk of tobacco-related cancers in Central Europe.
Lung Neoplasms
Genetic Polymorphisms and Platinum-Based Chemotherapy-Induced Toxicities in Patients With Lung Cancer: A Systematic Review and Meta-Analysis.
Lung Neoplasms
Heterozygote advantage of methylenetetrahydrofolate reductase polymorphisms on clinical outcomes in advanced non-small cell lung cancer (NSCLC) patients treated with platinum-based chemotherapy.
Lung Neoplasms
Hierarchical clustering of lung cancer cell lines using DNA methylation markers.
Lung Neoplasms
Impact of one-carbon metabolism-related gene polymorphisms on risk of lung cancer in Japan: a case control study.
Lung Neoplasms
Influence of methylenetetrahydrofolate reductase C677T polymorphism on the risk of lung cancer and the clinical response to platinum-based chemotherapy for advanced non-small cell lung cancer: an updated meta-analysis.
Lung Neoplasms
Influence of polymorphisms in MTHFR 677 C?T, TYMS 3R?2R and MTR 2756 A?G on NSCLC risk and response to platinum-based chemotherapy in advanced NSCLC.
Lung Neoplasms
Interaction of methylenetetrahydrofolate reductase genotype and smoking habit in Taiwanese lung cancer patients.
Lung Neoplasms
Lack of association between the MTHFRC677T polymorphism and lung cancer in a Turkish population.
Lung Neoplasms
Meta-analyses of the methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and risk of head and neck and lung cancer.
Lung Neoplasms
Meta-analysis of methylenetetrahydrofolate reductase polymorphism and lung cancer risk in Chinese.
Lung Neoplasms
Meta-analysis on MTHFR polymorphism and lung cancer susceptibility in East Asian populations.
Lung Neoplasms
Methylenetetrahydrofolate reductase 677TT genotype may be associated with an increased lung cancer risk in North China: an updated meta-analysis.
Lung Neoplasms
Methylenetetrahydrofolate reductase 677TT genotype might be associated with an increased lung cancer risk in Asians.
Lung Neoplasms
Methylenetetrahydrofolate reductase C677T polymorphism in patients with lung cancer in a Korean population.
Lung Neoplasms
Methylenetetrahydrofolate reductase C677T polymorphism predicts response and time to progression to gemcitabine-based chemotherapy for advanced non-small cell lung cancer in a Chinese Han population.
Lung Neoplasms
Methylenetetrahydrofolate reductase gene C677T and A1298C polymorphisms in patients with small cell and non-small cell lung cancer.
Lung Neoplasms
Methylenetetrahydrofolate Reductase Gene C677T Polymorphism and Lung Cancer: an Updated Meta-analysis.
Lung Neoplasms
Methylenetetrahydrofolate reductase gene polymorphisms and lung cancer: a meta-analysis.
Lung Neoplasms
Methylenetetrahydrofolate reductase polymorphisms and interaction with smoking and alcohol consumption in lung cancer risk: a case-control study in a Japanese population.
Lung Neoplasms
MTHFR C667T Polymorphism Association with Lung Cancer Risk in Henan Province: A Case-control Study.
Lung Neoplasms
MTHFR C677T and A1298C polymorphisms and lung cancer risk in a female Chinese population.
Lung Neoplasms
MTHFR C677T and A1298C polymorphisms and risk of lung cancer: a comprehensive evaluation.
Lung Neoplasms
Pharmacogenetics in cancer therapy - 8 years of experience at the Institute for Oncology and Radiology of Serbia.
Lung Neoplasms
Polymorphisms in folate metabolic genes and lung cancer risk in Xuan Wei, China.
Lung Neoplasms
Polymorphisms in thymidylate synthase and reduced folate carrier (SLC19A1) genes predict survival outcome in advanced non-small cell lung cancer patients treated with pemetrexed-based chemotherapy.
Lung Neoplasms
Polymorphisms of methylene-tetrahydrofolate reductase and risk of lung cancer: a case-control study.
Lung Neoplasms
Predicting chemosensitivity to gemcitabine and cisplatin based on gene polymorphisms and mRNA expression in non-small-cell lung cancer cells.
Lung Neoplasms
Prognostic significance of the polymorphisms in thymidylate synthase and methylenetetrahydrofolate reductase gene in lung cancer.
Lung Neoplasms
Quantitative analysis of DNA methylation profiles in lung cancer identifies aberrant DNA methylation of specific genes and its association with gender and cancer risk factors.
Lung Neoplasms
Quantitative assessment of the effect of MTHFR polymorphisms on the risk of lung carcinoma.
Lung Neoplasms
Sex differences in risk of lung cancer associated with methylene-tetrahydrofolate reductase polymorphisms.
Lung Neoplasms
The association between methylene-tetrahydrofolate reductase gene polymorphism and lung cancer risk.
Lung Neoplasms
The association between methylenetetrahydrofolate reductase 677C>T polymorphisms and breast cancer susceptibility: A meta-analysis based on Chinese Han population.
Lung Neoplasms
The influence of methylenetetrahydrofolate reductase and thymidylate synthetase gene polymorphisms on lung adenocarcinoma occurrence.
Lung Neoplasms
The methylenetetrahydrofolate reductase 677C-->T polymorphism and lung cancer risk in a Chinese population.
Lung Neoplasms
Variants in folate pathway genes as modulators of genetic instability and lung cancer risk.
Lung Neoplasms
[Association between genetic polymorphisms in methylentetrahydrofolate reductase and risk of lung cancer]
Lung Neoplasms
[Genetic polymorphisms in methylenetetrahydrofolate reductase and clinical response to chemotherapy in non-small cell lung cancer.]
Lupus Erythematosus, Systemic
Homocysteine, methylenetetrahydrofolate reductase polymorphism, antiphospholipid antibodies, and thromboembolic events in systemic lupus erythematosus: a retrospective cohort study.
Lupus Erythematosus, Systemic
Longitudinal myelitis in patient with systemic lupus erythematosus, homozygous prothrombin G20210A and heterozygous MTHFR 677T.
Lupus Erythematosus, Systemic
MTHFR polymorphisms (rs1801133) and systemic lupus erythematosus risk: A meta-analysis.
Lupus Erythematosus, Systemic
The 677C --> T mutation in the methylenetetrahydrofolate reductase (MTHFR) gene in epileptic patients affected by systemic lupus erythematosus.
Lupus Erythematosus, Systemic
The Association of MTHFR C677T and MTR A2756G Gene Polymorphisms With the Risk of Systemic Lupus Erythematosus: A Systematic Review and Meta-analysis.
Lupus Erythematosus, Systemic
[Prognostic value of allelic variants affecting the hemostatic system in the development of antiphospholipid syndrome and kidney lesion in patients with systemic lupus erythematosus].
Lyme Disease
Unilateral sequential papillophlebitis and central retinal artery occlusion in a young healthy patient.
Lymphatic Metastasis
The 677C > T mutation in 5,10-methylenetetrahydrofolate reductase and colorectal cancer risk.
Lymphoma
Association between the MTHFR A1298C polymorphism and risk of cancer: evidence from 265 case-control studies.
Lymphoma
Association of genetic polymorphism in the folate metabolic pathway with methotrexate pharmacokinetics and toxicity in childhood acute lymphoblastic leukaemia and malignant lymphoma.
Lymphoma
Association of MTHFR and ABCB1 polymorphisms with MTX-induced mucositis in Chinese paediatric patients with acute lymphoblastic leukaemia, lymphoma or osteosarcoma-A retrospective cohort study.
Lymphoma
Association of the methylenetetrahydrofolate reductase polymorphism in Korean patients with childhood acute lymphoblastic leukemia.
Lymphoma
Effects of methylenetetrahydrofolate reductase and reduced folate carrier 1 polymorphisms on high-dose methotrexate-induced toxicities in children with acute lymphoblastic leukemia or lymphoma.
Lymphoma
Genetic polymorphisms of methylenetetrahydrofolate reductase and promoter methylation of MGMT and FHIT genes in diffuse large B cell lymphoma risk in Middle East.
Lymphoma
Genetic polymorphisms predicting methotrexate blood levels and toxicity in adult non-Hodgkin lymphoma.
Lymphoma
High resolution array comparative genomic hybridization identifies copy number alterations in diffuse large B-cell lymphoma that predict response to immuno-chemotherapy.
Lymphoma
Influence of MTHFR and RFC1 polymorphisms on toxicities during maintenance chemotherapy for childhood acute lymphoblastic leukemia or lymphoma.
Lymphoma
Methotrexate elimination and toxicity: MTHFR 677C>T polymorphism in patients with primary CNS lymphoma treated with high-dose methotrexate.
Lymphoma
Methylenetetrahydrofolate reductase gene (MTHFR) polymorphisms and reduced risk of malignant lymphoma.
Lymphoma
Methylenetetrahydrofolate reductase gene polymorphisms association with the risk of diffuse large B cell lymphoma: a meta-analysis.
Lymphoma
Methylenetetrahydrofolate reductase genotype does not play a role in adult T-cell leukemia/lymphoma pathogenesis among human T-lymphotrophic virus type 1 carriers.
Lymphoma
Methylenetetrahydrofolate reductase genotype in diffuse large B-cell lymphomas with and without hypermethylation of the DNA repair gene O6-methylguanine DNA methyltransferase.
Lymphoma
MTHFR gene variants and non-MALT lymphoma development in primary Sjogren's syndrome.
Lymphoma, B-Cell
Association between folate-metabolizing pathway polymorphism and non-Hodgkin lymphoma.
Lymphoma, B-Cell
Genetic and epigenetic variants in the MTHFR gene are not associated with non-Hodgkin lymphoma.
Lymphoma, B-Cell
Genetic polymorphisms of methylenetetrahydrofolate reductase and promoter methylation of MGMT and FHIT genes in diffuse large B cell lymphoma risk in Middle East.
Lymphoma, B-Cell
Influence of MTHFR C677T Polymorphism on High-Dose Methotrexate-Related Toxicity in Patients With Primary Central Nervous System Diffuse Large B-Cell Lymphoma.
Lymphoma, B-Cell
Methylenetetrahydrofolate reductase gene polymorphisms association with the risk of diffuse large B cell lymphoma: a meta-analysis.
Lymphoma, B-Cell
Methylenetetrahydrofolate reductase genotype in diffuse large B-cell lymphomas with and without hypermethylation of the DNA repair gene O6-methylguanine DNA methyltransferase.
Lymphoma, B-Cell
The importance of negative results: methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms in diffuse large B-cell lymphomas (DLBCL).
Lymphoma, Follicular
Methylenetetrahydrofolate reductase gene polymorphisms association with the risk of follicular lymphoma: a meta-analysis.
Lymphoma, Follicular
Methylenetetrahydrofolate reductase genotype association with the risk of follicular lymphoma.
Lymphoma, Follicular
Polymorphisms and haplotypes in folate-metabolizing genes and risk of non-Hodgkin lymphoma.
Lymphoma, Large B-Cell, Diffuse
Association between folate-metabolizing pathway polymorphism and non-Hodgkin lymphoma.
Lymphoma, Large B-Cell, Diffuse
Genetic and epigenetic variants in the MTHFR gene are not associated with non-Hodgkin lymphoma.
Lymphoma, Large B-Cell, Diffuse
Genetic polymorphisms of methylenetetrahydrofolate reductase and promoter methylation of MGMT and FHIT genes in diffuse large B cell lymphoma risk in Middle East.
Lymphoma, Large B-Cell, Diffuse
Influence of MTHFR C677T Polymorphism on High-Dose Methotrexate-Related Toxicity in Patients With Primary Central Nervous System Diffuse Large B-Cell Lymphoma.
Lymphoma, Large B-Cell, Diffuse
Methylenetetrahydrofolate reductase gene polymorphisms association with the risk of diffuse large B cell lymphoma: a meta-analysis.
Lymphoma, Non-Hodgkin
Association of MTHFR C677T and A1298C polymorphisms with non-Hodgkin lymphoma susceptibility: evidence from a meta-analysis.
Lymphoma, Non-Hodgkin
Common gene polymorphisms in the metabolic folate and methylation pathway and the risk of acute lymphoblastic leukemia and non-Hodgkin's lymphoma in adults.
Lymphoma, Non-Hodgkin
Genetic and epigenetic variants in the MTHFR gene are not associated with non-Hodgkin lymphoma.
Lymphoma, Non-Hodgkin
Granulomatous reaction in mediastinal B-cell non-Hodgkin lymphoma and intracardiac thrombosis.
Lymphoma, Non-Hodgkin
Influence of Methylenetetrahydrofolate Reductase C677T and A1298C Polymorphism on High-Dose Methotrexate-Related Toxicities in Pediatric Non-Hodgkin Lymphoma Patients.
Lymphoma, Non-Hodgkin
Influence of MTHFR C677T and A1298C polymorphisms on the survival of pediatric patients with non-Hodgkin lymphoma.
Lymphoma, Non-Hodgkin
Methionine synthase genetic polymorphism MS A2756G alters susceptibility to follicular but not diffuse large B-cell non-Hodgkin's lymphoma or multiple myeloma.
Lymphoma, Non-Hodgkin
Methylenetetrahydrofolate reductase (MTHFR) 677C>T polymorphism and risk of pediatric non-Hodgkin lymphoma in a German study population.
Lymphoma, Non-Hodgkin
Methylenetetrahydrofolate reductase C677T and A1298C gene polymorphisms and therapy-related toxicity in children treated for acute lymphoblastic leukemia and non-Hodgkin lymphoma.
Lymphoma, Non-Hodgkin
Methylenetetrahydrofolate reductase C677T and A1298C gene variants in adult non-Hodgkin's lymphoma patients: association with toxicity and survival.
Lymphoma, Non-Hodgkin
Methylenetetrahydrofolate reductase gene polymorphisms (677C > T and 1298A > C) in Egyptian patients with non-Hodgkin lymphoma.
Lymphoma, Non-Hodgkin
MTHFR 677 (C-->T) polymorphism is not relevant for prognosis or therapy-associated toxicity in pediatric NHL: results from 484 patients of multicenter trial NHL-BFM 95.
Lymphoma, Non-Hodgkin
Polymorphisms in folate-metabolizing genes and risk of non-Hodgkin's lymphoma.
Lymphoma, Non-Hodgkin
Polymorphisms in methylenetetrahydrofolate reductase gene and risk of non-Hodgkin lymphoma in a multi-ethnic population.
Lymphoma, Non-Hodgkin
The Influence of MTHFR Gene Polymorphisms on the Outcome of Pediatric Non-Hodgkin Lymphoma Patients Treated with High-Dose Methotrexate.
Lymphoma, Non-Hodgkin
[A new method for 5, 10-methylenetetrahydrofolate reductase single nucleotide polymorphisms genotyping used to study susceptibility of hematological malignancy]
Lymphoma, T-Cell
Association between folate-metabolizing pathway polymorphism and non-Hodgkin lymphoma.
Lymphoproliferative Disorders
Methylenetetrahydrofolate reductase C677T polymorphism in adult patients with lymphoproliferative disorders and its effect on chemotherapy.
Lymphoproliferative Disorders
Normal frequencies of the C677T genotypes on the methylenetetrahydrofolate reductase (MTHFR) gene among lymphoproliferative disorders but not in multiple myeloma.
Macular Degeneration
Homocysteine, B Vitamins, MTHFR Genotype, and Incident Age-related Macular Degeneration.
Macular Degeneration
Impact of methylenetetrahydrofolate reductase C677T polymorphism on the efficacy of photodynamic therapy in patients with neovascular age-related macular degeneration.
Macular Degeneration
Predictive role of C677T MTHFR polymorphism in variable efficacy of photodynamic therapy for neovascular age-related macular degeneration.
Malaria
Environmental influence on the worldwide prevalence of a 776C->G variant in the transcobalamin gene (TCN2).
Malaria
Increased Resistance to Malaria in Mice with Methylenetetrahydrofolate Reductase (Mthfr) Deficiency Suggests a Mechanism for Selection of the MTHFR 677C>T (c.665C>T) Variant.
Malaria
Possible selection of host folate pathway gene polymorphisms in patients with malaria from a malaria endemic region in North East India.
Malaria, Cerebral
Increased Resistance to Malaria in Mice with Methylenetetrahydrofolate Reductase (Mthfr) Deficiency Suggests a Mechanism for Selection of the MTHFR 677C>T (c.665C>T) Variant.
Malnutrition
Methylenetetrahydrofolate reductase gene C677T polymorphism, homocysteine, vitamin B12, and DNA damage in coronary artery disease.
Malnutrition
Methylenetetrahydrofolate reductase gene, homocysteine and coronary artery disease: The A1298C polymorphism does matter. Inferences from a case study (Madeira, Portugal).
Malnutrition
MTHFR deficiency or reduced intake of folate or choline in pregnant mice results in impaired short-term memory and increased apoptosis in the hippocampus of wild-type offspring.
Malnutrition
Vascular and cellular stress in inflammatory bowel disease: revisiting the role of homocysteine.
Mania
A prospective study to explore the relationship between MTHFR C677T genotype, physiological folate levels, and postpartum psychopathology in at-risk women.
Maple Syrup Urine Disease
Epidemiology of rare diseases detected by newborn screening in the Czech Republic.
Marfan Syndrome
Phenotypic variability of cardiovascular manifestations in Marfan Syndrome. Possible role of hyperhomocysteinemia and C677T MTHFR gene polymorphism.
Mastitis
Relationship between granulomatous lobular mastitis and methylene tetrahydrofolate reductase gene polymorphism.
medium-chain acyl-coa dehydrogenase deficiency
Epidemiology of rare diseases detected by newborn screening in the Czech Republic.
Medulloblastoma
MTHFR single nucleotide polymorphism associated with working memory in pediatric medulloblastoma survivors.
Memory Disorders
Epigenetic Factors in Late-Onset Alzheimer's Disease: MTHFR and CTH Gene Polymorphisms, Metabolic Transsulfuration and Methylation Pathways, and B Vitamins.
Memory Disorders
High homocysteine and epistasis between MTHFR and APOE: association with cognitive performance in the elderly.
Memory Disorders
MTHFR deficiency or reduced intake of folate or choline in pregnant mice results in impaired short-term memory and increased apoptosis in the hippocampus of wild-type offspring.
Meningioma
5,10-Methylenetetrahydrofolate reductase (MTHFR), methionine synthase (MTRR), and methionine synthase reductase (MTR) gene polymorphisms and adult meningioma risk.
Meningioma
Association of MTHFR, MTRR and RAD54L Gene Variations with Meningioma and Correlation with Tumor's Histopathological Characteristics on Turkish Cohort.
Meningioma
Association of Single Nucleotide Polymorphisms (SNPs) in Genes Encoding for Folate Metabolising Enzymes with Glioma and Meningioma in Indian Population
Meningioma
C677T gene polymorphism of methylenetetrahydrofolate reductase (MTHFR) in meningiomas and high-grade gliomas.
Meningioma
Folate metabolism genetic polymorphisms and meningioma and glioma susceptibility in adults.
Meningioma
Functional polymorphisms in folate metabolism genes influence the risk of meningioma and glioma.
Meningioma
Risk association of meningiomas with MTHFR C677T and GSTs polymorphisms: a meta-analysis.
Meningomyelocele
Deep sequencing study of the MTHFR gene to identify variants associated with myelomeningocele.
Meningomyelocele
Folate metabolism gene 5,10-methylenetetrahydrofolate reductase (MTHFR) is associated with ADHD in myelomeningocele patients.
Meningomyelocele
Homocysteine, folate, lipid profile and MTHFR genotype and disability in children with myelomeningocele.
Meningomyelocele
No evidence for heterozygote advantage at MTHFR in patients with lumbosacral myelomeningocele or their relatives.
Meningomyelocele
Possible interaction of genotypes at cystathionine beta-synthase and methylenetetrahydrofolate reductase (MTHFR) in neural tube defects. NTD Collaborative Group.
Meningomyelocele
The effect of C677T mutation of methylene tetrahydrofolate reductase gene and plasma folate level on hyperhomocysteinemia in patients with meningomyelocele.
Menkes Kinky Hair Syndrome
Diagnostic yield of genetic testing in epileptic encephalopathy in childhood.
Mesenteric Ischemia
Combined portal, splenic and mesenteric venous thrombosis in inactive ulcerative colitis with heterozygous mutation in MTHFR gene: A rare case of thrombophilia.
Mesenteric Ischemia
Heterozygous prothrombin 20210G/A mutation, associated with hyperhomocysteinemia, and homozygous methylenetetrahydrofolate reductase 677C/T mutation, in a patient with portal and mesenteric venous thrombosis.
Mesenteric Ischemia
Mesenteric venous thrombosis with bowel infarction and hyperhomocysteinemia due to homozygous methylenetetrahydrofolate reductase C677T genotype.
Mesothelioma
Correlation between TS, MTHFR, and ERCC1 gene polymorphisms and the efficacy of platinum in combination with pemetrexed first-line chemotherapy in mesothelioma patients.
Metabolic Syndrome
A Genetic Association Study of MTHFR C677T Polymorphism with Risk of Metabolic Syndrome: A Systematic Review and Meta-Analysis.
Metabolic Syndrome
Association between folate metabolism-related polymorphisms and colorectal cancer risk.
Metabolic Syndrome
Association Between Polymorphisms in MTHFR and APOA5 and Metabolic Syndrome in the Greek Population.
Metabolic Syndrome
Association of FTO, LEPR and MTHFR gene polymorphisms with metabolic syndrome in schizophrenia patients receiving antipsychotics.
Metabolic Syndrome
Association of homocysteinemia with high concentrations of serum insulin and uric acid in Brazilian subjects with metabolic syndrome genotyped for C677T polymorphism in the methylenetetrahydrofolate reductase gene.
Metabolic Syndrome
Association of Methylenetetrahydrofolate Reductase (MTHFR) A1298C Polymorphism with Lower High-Density Lipoprotein Cholesterol Level.
Metabolic Syndrome
Association of MTHFR C677T gene polymorphism with metabolic syndrome in a Chinese population: a case-control study.
Metabolic Syndrome
Association of uricemia with biochemical and dietary factors in human adults with metabolic syndrome genotyped to C677T polymorphism in the methylenetetrahydrofolate reductase gene.
Metabolic Syndrome
Associations of MTHFR C677T and MTRR A66G gene polymorphisms with metabolic syndrome: a case-control study in Northern China.
Metabolic Syndrome
C677T gene polymorphism of MTHFR and metabolic syndrome: response to dietary intervention.
Metabolic Syndrome
Cyclic supplementation of 5-MTHF is effective for the correction of hyperhomocysteinemia.
Metabolic Syndrome
Detection of metabolic syndrome in schizophrenia and implications for antipsychotic therapy : is there a role for folate?
Metabolic Syndrome
Gene-environment interactions between methylenetetrahydrofolate reductase (MTHFR) 677C>T and metabolic syndrome for the prevalence of ischemic stroke in Koreans.
Metabolic Syndrome
Hyperhomocysteinemia and homozygous MTHFR 677C>T mutation finding in an Alzheimer's disease case with metabolic syndrome diagnosis.
Metabolic Syndrome
Investigation of potential biomarkers for thrombosis related diseases in Turkish Cypriot population.
Metabolic Syndrome
Is there an association between the development of metabolic syndrome in PCOS patients and the C677T MTHFR gene polymorphism?
Metabolic Syndrome
Metabolic syndrome and insulin resistance in schizophrenia patients receiving antipsychotics genotyped for the methylenetetrahydrofolate reductase (MTHFR) 677C/T and 1298A/C variants.
Metabolic Syndrome
Polymorphisms of genes for brain-derived neurotrophic factor, methylenetetrahydrofolate reductase, tyrosine hydroxylase, and endothelial nitric oxide synthase in depression and metabolic syndrome.
Metabolic Syndrome
Relationship between Metabolic Syndrome and MTHFR Polymorphism in Colorectal Cancer.
Metabolic Syndrome
Risk factors associated with metabolic syndrome in bipolar and schizophrenia subjects treated with antipsychotics: the role of folate pharmacogenetics.
Metabolic Syndrome
[Remodeling of the cardiovascular system and development of chronic kidney disease in patients with metabolic syndrome and obesity: role of eNOS, subunit p22-phox of NADPH-oxidase and MTHFR genes].
Metabolism, Inborn Errors
Inborn Errors of Metabolism Associated With Autism Spectrum Disorders: Approaches to Intervention.
methionine adenosyltransferase deficiency
Reversible leukoencephalopathy with acute neurological deterioration and permanent residua in classical homocystinuria: A case report.
methionine synthase deficiency
Comparison of folic acid coenzyme distribution patterns in patients with methylenetetrahydrofolate reductase and methionine synthetase deficiencies.
methionine synthase deficiency
Methionine and serine formation in control and mutant human cultured fibroblasts: evidence for methyl trapping and characterization of remethylation defects.
methionine synthase deficiency
Methionine synthase deficiency without megaloblastic anaemia.
methionine synthase deficiency
Update and new concepts in vitamin responsive disorders of folate transport and metabolism.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
5,10-Methylenetetrahydrofolate reductase (MTHFR) assay in the forward direction: residual activity in MTHFR deficiency.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
5,10-Methylenetetrahydrofolate reductase deficiency with progressive polyneuropathy in an infant.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
A genetic deficiency in folic acid metabolism impairs recovery after ischemic stroke.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
A Novel Homozygous Non-sense Mutation in the Catalytic Domain of MTHFR Causes Severe 5,10-Methylenetetrahydrofolate Reductase Deficiency.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
A rationale for cystine supplementation in severe homocystinuria.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Acquired and inherited disorders of cobalamin and folate in children.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Acute leukoencephalopathy possibly induced by phenytoin intoxication in an adult patient with methylenetetrahydrofolate reductase deficiency.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Adolescence/adult onset MTHFR deficiency may manifest as isolated and treatable distinct neuro-psychiatric syndromes.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Adolescent/adult-onset homocysteine remethylation disorders characterized by gait disturbance with/without psychiatric symptoms and cognitive decline: a series of seven cases.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Adult-onset methylenetetrahydrofolate reductase deficiency.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Adult-onset severe methylenetetrahydrofolate reductase deficiency characterized by reversible spastic paraplegia with a novel mutation.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Altered protein phosphatase 2A methylation and Tau phosphorylation in the young and aged brain of methylenetetrahydrofolate reductase (MTHFR) deficient mice.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
An early onset form of methylenetetrahydrofolate reductase deficiency: a report of a family from Kuwait.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Anesthesia for cesarean section in a patient with placenta previa and methylenetetrahydrofolate reductase deficiency.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
B-vitamin and choline supplementation increases neuroplasticity and recovery after stroke.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Betaine for treatment of homocystinuria caused by methylenetetrahydrofolate reductase deficiency.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Betaine rescue of an animal model with methylenetetrahydrofolate reductase deficiency.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Betaine supplementation improves the atherogenic risk factor profile in a transgenic mouse model of hyperhomocysteinemia.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Characterization of a pseudogene for murine methylenetetrahydrofolate reductase.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Characterization of mutations in severe methylenetetrahydrofolate reductase deficiency reveals an FAD-responsive mutation.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Characterization of six novel mutations in the methylenetetrahydrofolate reductase (MTHFR) gene in patients with homocystinuria.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Clinical and molecular characterization of adult patients with late-onset MTHFR deficiency.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Clinical pattern, mutations and in vitro residual activity in 33 patients with severe 5, 10 methylenetetrahydrofolate reductase (MTHFR) deficiency.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Clinical presentation of seven patients with Methylenetetrahydrofolate reductase deficiency.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Clinical, fluorine-18 labeled 2-fluoro-2-deoxyglucose positron emission tomography of the brain, MR spectroscopy, and therapeutic attempts in methylenetetrahydrofolate reductase deficiency.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Complete deficiency of methylenetetrahydrofolate reductase in mice is associated with impaired retinal function and variable mortality, hematological profiles, and reproductive outcomes.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Congenital errors of folate metabolism.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Congenital MTHFR deficiency causing early-onset cerebral stroke in a case homozygous for MTHFR thermolabile variant.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Defects in homocysteine metabolism: diversity among hyperhomocyst(e)inemias.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Detection of homozygotes and heterozygotes with methylenetetrahydrofolate reductase deficiency.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Determination of CSF 5-methyltetrahydrofolate in children and its application for defects of folate transport and metabolism.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Diagnostic yield of genetic testing in epileptic encephalopathy in childhood.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Diffuse multicystic encephalomalacia in a preterm baby due to homozygous methylenetetrahydrofolate reductase 677 C-->T mutation.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Disorders of intermediary metabolism: toxic leukoencephalopathies.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Disturbed One-Carbon Metabolism Causing Adverse Reproductive Outcomes in Mice Is Associated with Altered Expression of Apolipoprotein AI and Inflammatory Mediators PPAR?, Interferon-?, and Interleukin-10.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Early Manifestations of Brain Aging in Mice Due to Low Dietary Folate and Mild MTHFR Deficiency.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Early treatment using betaine and methionine for a neonate with MTHFR deficiency.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Effect of betaine on S-adenosylmethionine levels in the cerebrospinal fluid in a patient with methylenetetrahydrofolate reductase deficiency and peripheral neuropathy.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Epidemiology of rare diseases detected by newborn screening in the Czech Republic.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Erratum to: Treatment with Mefolinate (5-Methyltetrahydrofolate), but Not Folic Acid or Folinic Acid, Leads to Measurable 5-Methyltetrahydrofolate in Cerebrospinal Fluid in Methylenetetrahydrofolate Reductase Deficiency.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Ethnogeographic prevalence and implications of the 677C>T and 1298A>C MTHFR polymorphisms in US primary care populations.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Expanded carrier screening in gamete donors of Venezuela.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Folate Insufficiency Due to MTHFR Deficiency Is Bypassed by 5-Methyltetrahydrofolate.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Folic acid nonresponsive homocystinuria due to methylenetetrahydrofolate reductase deficiency.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Functional characterization of human methylenetetrahydrofolate reductase in Saccharomyces cerevisiae.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Functional characterization of missense mutations in severe methylenetetrahydrofolate reductase deficiency using a human expression system.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Gender-specific effect of Mthfr genotype and neonatal vigabatrin interaction on synaptic proteins in mouse cortex.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Gene structure of human and mouse methylenetetrahydrofolate reductase (MTHFR)
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
General anesthesia and methylenetetrahydrofolate reductase deficiency.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Genome-wide Hypomethylation in Human Glioblastomas Associated with Specific Copy Number Alteration, Methylenetetrahydrofolate Reductase Allele Status, and Increased Proliferation.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Genomic structure and transcript variants of the human methylenetetrahydrofolate reductase gene.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Glutamatergic synapse protein composition of wild-type mice is sensitive to in utero MTHFR genotype and the timing of neonatal vigabatrin exposure.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Guidelines for diagnosis and management of the cobalamin-related remethylation disorders cblC, cblD, cblE, cblF, cblG, cblJ and MTHFR deficiency.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
High dietary folate in pregnant mice leads to pseudo-MTHFR deficiency and altered methyl metabolism, with embryonic growth delay and short-term memory impairment in offspring.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
High intake of folic acid disrupts embryonic development in mice.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Homocysteinemia due to MTHFR deficiency in a young adult presenting with bilateral lens subluxations.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Human methylenetetrahydrofolate reductase: isolation of cDNA, mapping and mutation identification.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Hydrocephalus internus in two patients with 5,10-methylenetetrahydrofolate reductase deficiency.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Hyperhomocysteinaemia and associated disease.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Hyperhomocysteinemia and arterial aneurysm.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Hyperhomocysteinemia is associated with hypertriglyceridemia in mice with methylenetetrahydrofolate reductase deficiency.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Identification and origin of N?-homocysteinyl-lysine isopeptide in humans and mice.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Identification of four novel mutations in severe methylenetetrahydrofolate reductase deficiency.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Identification of small molecule allosteric modulators of 5,10-methylenetetrahydrofolate reductase (MTHFR) by targeting its unique regulatory domain.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Impact of methylenetetrahydrofolate reductase deficiency and low dietary folate on the development of neural tube defects in splotch mice.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Increased neurotoxicity of arsenic in methylenetetrahydrofolate reductase deficiency.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Increased Resistance to Malaria in Mice with Methylenetetrahydrofolate Reductase (Mthfr) Deficiency Suggests a Mechanism for Selection of the MTHFR 677C>T (c.665C>T) Variant.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Increased susceptibility to mild neonatal stress in MTHFR deficient mice.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Infertility in 5,10-methylenetetrahydrofolate reductase (MTHFR)-deficient male mice is partially alleviated by lifetime dietary betaine supplementation.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Insidious peripheral neuropathy occurring under treatment in infantile MTHFR deficiency.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Intermediate hyperhomocysteinaemia and compound heterozygosity for the common variant c.677C>T and a MTHFR gene mutation.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Intermediate hyperhomocysteinemia resulting from compound heterozygosity of methylenetetrahydrofolate reductase mutations.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Intermittent encephalopathy, reversible nerve conduction slowing, and MRI evidence of cerebral white matter disease in methylenetetrahydrofolate reductase deficiency.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Intrauterine vascular deficiency secondary to methylenetetrahydrofolate reductase deficiency: 2 case reports.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Isolated remethylation disorders: do our treatments benefit patients?
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Life-threatening methylenetetrahydrofolate reductase (MTHFR) deficiency with extremely early onset: Characterization of two novel mutations in compound heterozygous patients.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Long term treatment with betaine in methylenetetrahydrofolate reductase deficiency.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Low dietary choline and low dietary riboflavin during pregnancy influence reproductive outcomes and heart development in mice.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Low dietary folate and methylenetetrahydrofolate reductase deficiency may lead to pregnancy complications through modulation of ApoAI and IFN-? in spleen and placenta, and through reduction of methylation potential.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Manifestations of neurological symptoms and thromboembolism in adults with MTHFR-deficiency.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Maternal methylenetetrahydrofolate reductase deficiency and low dietary folate lead to adverse reproductive outcomes and congenital heart defects in mice.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Mefolinate (5-methyltetrahydrofolate), but not folic acid, decreases mortality in an animal model of severe methylenetetrahydrofolate reductase deficiency.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Methotrexate-induced apoptosis is enhanced by altered expression of methylenetetrahydrofolate reductase.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Methylene Tetrahydrofolate Reductase Deficiency.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Methylene Tetrahydrofolate Reductase Deficiency: the Hidden Risk in Paediatric Anaesthesia.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Methylenetetrahydrofolate reductase (MTHFR) deficiency and infantile epilepsy.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Methylenetetrahydrofolate reductase (MTHFR) deficiency enhances resistance against cytomegalovirus infection.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Methylenetetrahydrofolate reductase (MTHFR) deficiency presenting as a rash.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Methylenetetrahydrofolate reductase deficiency (homocystinuria type II) as a rare cause of rapidly progressive tetraspasticity and psychosis in a previously healthy adult.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Methylenetetrahydrofolate reductase deficiency alters cellular response after ischemic stroke in male mice.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Methylenetetrahydrofolate reductase deficiency alters levels of glutamate and ?-aminobutyric acid in brain tissue.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Methylenetetrahydrofolate reductase deficiency and low dietary folate increase embryonic delay and placental abnormalities in mice.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Methylenetetrahydrofolate reductase deficiency and low dietary folate reduce tumorigenesis in Apc min/+ mice.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Methylenetetrahydrofolate Reductase Deficiency as a Cause of Treatable Adult-onset Leukoencephalopathy and Myelopathy.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Methylenetetrahydrofolate Reductase Deficiency Deregulates Regional Brain Amyloid-? Protein Precursor Expression and Phosphorylation Levels.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Methylenetetrahydrofolate reductase deficiency in a patient with phenotypic findings of Angelman syndrome.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Methylenetetrahydrofolate reductase deficiency in four siblings: a clinical, biochemical, and molecular study of the family.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Methylenetetrahydrofolate reductase deficiency revealed by a neuropathy in a psychotic adult.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Methylenetetrahydrofolate Reductase Deficiency: A Case Report.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Methylenetetrahydrofolate reductase deficiency: importance of early diagnosis.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Methylenetetrahydrofolate reductase deficiency: prenatal diagnosis and family studies.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Methylenetetrahydrofolate Reductase Deficiency: Rare but Considerable.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Methylenetetrahydrofolate reductase in cultured human cells. II. Genetic and biochemical studies of methylenetetrahydrofolate reductase deficiency.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Mice deficient in methylenetetrahydrofolate reductase exhibit hyperhomocysteinemia and decreased methylation capacity, with neuropathology and aortic lipid deposition.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Mice deficient in methylenetetrahydrofolate reductase exhibit tissue-specific distribution of folates.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Microarray analysis of brain RNA in mice with methylenetetrahydrofolate reductase deficiency and hyperhomocysteinemia.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Mild Methylenetetrahydrofolate Reductase Deficiency Alters Inflammatory and Lipid Pathways in Liver.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Molecular biology of 5,10-methylenetetrahydrofolate reductase.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Molecular characterization of five patients with homocystinuria due to severe methylenetetrahydrofolate reductase deficiency.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Molecular genetics of methylenetetrahydrofolate reductase deficiency.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
MR and proton MR spectroscopy of the brain in hyperhomocysteinemia caused by methylenetetrahydrofolate reductase deficiency.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Mthfr as a modifier of the retinal phenotype of Crb1(rd8/rd8) mice.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
MTHFR C677T polymorphism is associated with hyperlipidemia in women with polycystic ovary syndrome.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Mthfr deficiency induces endothelial progenitor cell senescence via uncoupling of eNOS and downregulation of SIRT1.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
MTHFR deficiency or reduced intake of folate or choline in pregnant mice results in impaired short-term memory and increased apoptosis in the hippocampus of wild-type offspring.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
MTHFR: Addressing Genetic Counseling Dilemmas Using Evidence-Based Literature.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Multiple transcription start sites and alternative splicing in the methylenetetrahydrofolate reductase gene result in two enzyme isoforms.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Mutation Update and Review of Severe Methylenetetrahydrofolate Reductase Deficiency.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Mutations of the MTHFR gene (428C>T and [458G>T+459C>T]) markedly decrease MTHFR enzyme activity.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Newborn screening for homocystinurias and methylation disorders: systematic review and proposed guidelines.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Newborn screening for homocystinurias: recent recommendations versus current practice.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Newborn screening for homocystinurias: Recent recommendations versus current practice.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Outcomes of four patients with homocysteine remethylation disorders detected by newborn screening.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Paternal MTHFR deficiency leads to hypomethylation of young retrotransposons and reproductive decline across two successive generations.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Pathogenicity of thermolabile methylenetetrahydrofolate reductase for vascular dementia.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Pearls & oy-sters: familial epileptic encephalopathy due to methylenetetrahydrofolate reductase deficiency.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Phenotype, treatment practice and outcome in the cobalamin-dependent remethylation disorders and MTHFR deficiency: data from the E-HOD registry.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Phenotype, treatment practice and outcome in the cobalamin-dependent remethylation disorders and MTHFR deficiency: Data from the E-HOD registry.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Posterior-predominant leukoencephalopathy which was caused by methylenetetrahydrofolate reductase deficiency and successfully treated with folic acid.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Postnatal cerebellar defects in mice deficient in methylenetetrahydrofolate reductase.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Pregnancy outcomes in women with epilepsy and MTHFR mutations supplemented with methylated folate and methylcobalamin (methylated B12).
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Prenatal diagnosis for methylenetetrahydrofolate reductase deficiency.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Prenatal diagnosis for severe methylenetetrahydrofolate reductase deficiency by linkage analysis and enzymatic assay.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Prenatal Nutritional Intervention Reduces Autistic-Like Behavior Rates Among Mthfr-Deficient Mice.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Protein-bound homocyst(e)ine in normal subjects and in patients with homocystinuria.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Psychosis, paraplegia and coma revealing methylenetetrahydrofolate reductase deficiency in a 56-year-old woman.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Psychotic symptoms in severe MTHFR deficiency and their successful treatment with betaine.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Quantitative proteomics reveals differentially expressed proteins in murine preneoplastic intestine in a model of intestinal tumorigenesis induced by low dietary folate and MTHFR deficiency.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Rapidly progressive psychotic symptoms triggered by infection in a patient with methylenetetrahydrofolate reductase deficiency: a case report.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
RE: Methylenetetrahydrofolate Reductase Deficiency: Rare but Considerable.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Relations between molecular and biological abnormalities in 11 families from siblings affected with methylenetetrahydrofolate reductase deficiency.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Remethylation defects: guidelines for clinical diagnosis and treatment.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Retinal ganglion cell loss and mild vasculopathy in methylene tetrahydrofolate reductase (Mthfr) deficient mice: a model of mild hyperhomocysteinemia.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Retinal vein occlusion associated with methylenetetrahydrofolate reductase mutation.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Reversible leukoencephalopathy and cerebral atrophy in Homocystinuria due to MTHFR deficiency: A treatable metabolic disorder.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Reversible leukoencephalopathy with acute neurological deterioration and permanent residua in classical homocystinuria: A case report.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Sequence Variation of the Methylene Tetrahydrofolate Reductase Gene (677C>T and 1298?A>C) and Traditional Risk Factors in a South Indian Population.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Seven novel mutations in the methylenetetrahydrofolate reductase gene and genotype/phenotype correlations in severe methylenetetrahydrofolate reductase deficiency.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Severe 5,10-methylenetetrahydrofolate reductase deficiency and two MTHFR variants in an adolescent with progressive myoclonic epilepsy.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Severe 5,10-methylenetetrahydrofolate reductase deficiency: a rare, treatable cause of complicated hereditary spastic paraplegia.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Severe and mild mutations in cis for the methylenetetrahydrofolate reductase (MTHFR) gene, and description of five novel mutations in MTHFR.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Severe atherosclerosis in rheumatoid arthritis and hyperhomocysteinemia: is there a link?
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Severe methylenetetrahydrofolate reductase (MTHFR) deficiency: a case report of nonclassical homocystinuria.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Severe methylenetetrahydrofolate reductase deficiency in mice results in behavioral anomalies with morphological and biochemical changes in hippocampus.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Severe methylenetetrahydrofolate reductase deficiency revealed by a pulmonary embolism in a young adult.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Severe methylenetetrahydrofolate reductase deficiency, methionine synthase, and nitrous oxide--a cautionary tale.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Severe methylenetetrahydrofolate reductase deficiency: clinical clues to a potentially treatable cause of adult-onset hereditary spastic paraplegia.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Severe scoliosis in a patient with severe methylenetetrahydrofolate reductase deficiency.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Severe skin necrosis after breast reconstruction with a transverse rectus abdominis musculocutaneous flap in methylenetetrahydrofolate reductase deficiency.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Sex-dependent behavioral effects of Mthfr deficiency and neonatal GABA potentiation in mice.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Shifting landscapes of human MTHFR missense-variant effects.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Stability of DNA Methylation Patterns in Mouse Spermatogonia Under Conditions of MTHFR Deficiency and Methionine Supplementation.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Strain-Specific Defects in Testicular Development and Sperm Epigenetic Patterns in 5,10-Methylenetetrahydrofolate Reductase-Deficient Mice.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Supplementation with apple juice can compensate for folate deficiency in a mouse model deficient in methylene tetra hydrofoate reductase activity.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Survival and psychomotor development with early betaine treatment in patients with severe methylenetetrahydrofolate reductase deficiency.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Symptomatic and asymptomatic methylenetetrahydrofolate reductase deficiency in two adult brothers.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Targeted cerebrospinal fluid analysis for inborn errors of metabolism on an LC-MS/MS analysis platform.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Targeted insertion of two Mthfr promoters in mice reveals temporal- and tissue-specific regulation.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Testicular MTHFR deficiency may explain sperm DNA hypomethylation associated with high dose folic acid supplementation.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
The 1316T>C missenses mutation in MTHFR contributes to MTHFR deficiency by targeting MTHFR to proteasome degradation.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
The clinical presentation of cobalamin-related disorders: From acquired deficiencies to inborn errors of absorption and intracellular pathways.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
The Effect of in Vitro Homocystinuria on the Suckling Rat Hippocampal Acetylcholinesterase.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
The effect of in vitro homocystinuria on the suckling rat hippocampal acetylcholinesterase.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
The thermolabile variant 677C-->T can further reduce activity when expressed in cis with severe mutations for human methylenetetrahydrofolate reductase.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Thermolabile methylenetetrahydrofolate reductase: an inherited risk factor for coronary artery disease.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Treatment of inherited homocystinurias.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Treatment with Mefolinate (5-Methyltetrahydrofolate), but Not Folic Acid or Folinic Acid, Leads to Measurable 5-Methyltetrahydrofolate in Cerebrospinal Fluid in Methylenetetrahydrofolate Reductase Deficiency.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Two-Tier Approach to the Newborn Screening of Methylenetetrahydrofolate Reductase Deficiency and Other Remethylation Disorders with Tandem Mass Spectrometry.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Update and new concepts in vitamin responsive disorders of folate transport and metabolism.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
Valproic acid increases expression of methylenetetrahydrofolate reductase (MTHFR) and induces lower teratogenicity in MTHFR deficiency.
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
[Case of juvenile stroke caused by methylenetetrahydrofolate reductase deficiency]
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
[Cystathionine betasynthase and MTHFR deficiencies in adults]
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
[Diet therapy and coenzyme therapy in hereditary metabolic diseases]
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
[Effect of folic acid for treatment of homocystinuria due to 5,10-methylenetetrahydrofolate reductase deficiency]
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
[Hyperhomocysteinemia--a risk factor for development of occlusive vascular diseases]
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
[Methylenetetrahydrofolate reductase deficiency-induced schizophrenia in a school-age boy].
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
[Methylenetetrahydrofolate reductase deficiency]
methylenetetrahydrofolate dehydrogenase (nad+) deficiency
[Molecular genetics of MTHFR: polymorphisms are not all benign]
Micrognathism
A Bibliometric Analysis of Cleft Lip and Palate-Related Publication Trends From 2000 to 2017.
Microvascular Angina
Endothelial cell dysfunction in women with cardiac syndrome X and MTHFR C677T mutation.
Migraine Disorders
Aberrant DNA methylation pattern may enhance susceptibility to migraine: A novel perspective.
Migraine Disorders
Are the methylenetetrahydrofolate reductase 1298 and 677 gene polymorphisms related to optic glioma and hamartoma risk in neurofibromatosis type 1 patients?
Migraine Disorders
Association of MTHFR C677T polymorphism with susceptibility to migraine in the Chinese population.
Migraine Disorders
Association of MTHFR gene polymorphisms with migraine in North Indian population.
Migraine Disorders
Association of the C677T and A1298C polymorphisms in the 5,10 methylenetetrahydrofolate reductase gene in patients with migraine risk.
Migraine Disorders
Association of the C677T polymorphism in the MTHFR gene with migraine: a meta-analysis.
Migraine Disorders
Association of von Willebrand factor activity with ACE I/D and MTHFR C677T polymorphisms in migraine.
Migraine Disorders
Comment on Rubino et al., 'Association of the C677T polymorphism in the MTHFR gene with migraine: a meta-analysis'.
Migraine Disorders
Do Folate, Vitamins B6 and B12 Play a Role in the Pathogenesis of Migraine? The Role of Pharmacoepigenomics.
Migraine Disorders
Effects of MTHFR C677T and A1298C Polymorphisms on Migraine Susceptibility: A Meta-Analysis of 26 Studies.
Migraine Disorders
Effects of MTHFR gene polymorphism on the clinical and electrophysiological characteristics of migraine.
Migraine Disorders
Efficacy of Folic Acid in Children With Migraine, Hyperhomocysteinemia and MTHFR Polymorphisms.
Migraine Disorders
Emerging Role of Polymorphisms of the MTHFR Gene in Systemic Carcinogenesis Besides Their Role in Migraines.
Migraine Disorders
Frequency of the C677T variant of the methylenetetrahydrofolate reductase (MTHFR) gene in patients with migraine with or without aura - a preliminary report.
Migraine Disorders
Genetic variants of angiotensin converting enzyme and methylenetetrahydrofolate reductase may act in combination to increase migraine susceptibility.
Migraine Disorders
Genotypes of the MTHFR C677T and MTRR A66G genes act independently to reduce migraine disability in response to vitamin supplementation.
Migraine Disorders
Haplotype analysis of the folate-related genes MTHFR, MTRR, and MTR and migraine with aura.
Migraine Disorders
Influence of MTHFR genotype on contingent negative variation and MRI abnormalities in migraine.
Migraine Disorders
Inherited prothrombotic risk factors in children with stroke, transient ischemic attack, or migraine.
Migraine Disorders
Interrelationships among the MTHFR 677C>T polymorphism, migraine, and cardiovascular disease.
Migraine Disorders
Investigation of MTHFR C677T Gene Polymorphism, Biochemical and Clinical Parameters in Turkish Migraine Patients: Association with Allodynia and Fatigue.
Migraine Disorders
Is an "Epigenetic Diet" for Migraines Justified? The Case of Folate and DNA Methylation.
Migraine Disorders
Joint Metabonomic and Instrumental Analysis for the Classification of Migraine Patients with 677-MTHFR Mutations.
Migraine Disorders
Lack of association between the MTHFR C677T variant and migraine with aura in an older population: Could selective survival play a role?
Migraine Disorders
MAOA, MTHFR, and TNF-? genes polymorphisms and personality traits in the pathogenesis of migraine.
Migraine Disorders
Methylenetetrahydrofolate reductase (MTHFR) gene polymorphism and migraine.
Migraine Disorders
Methylenetetrahydrofolate reductase gene variant (MTHFR C677T) and migraine: a case control study and meta-analysis.
Migraine Disorders
Methylenetetrahydrofolate reductase polymorphism (MTHFR C677T) and headache in children: a retrospective study from a tertiary level outpatient service.
Migraine Disorders
Migraine and coronary artery disease: an open study on the genetic polymorphism of the 5, 10 methylenetetrahydrofolate (MTHFR) and angiotensin I-converting enzyme (ACE) genes.
Migraine Disorders
Migraine mediates the influence of C677T MTHFR genotypes on ischemic stroke risk with a stroke-subtype effect.
Migraine Disorders
MTHFR 677C-->T and ACE D/I polymorphisms and migraine attack frequency in women.
Migraine Disorders
MTHFR 677C>T and ACE D/I Polymorphisms in Migraine: A Systematic Review and Meta-Analysis.
Migraine Disorders
MTHFR and ACE Polymorphisms Do Not Increase Susceptibility to Migraine Neither Alone Nor in Combination.
Migraine Disorders
Predictive index for the onset of medication overuse headache in migraine patients.
Migraine Disorders
Role of Methylenetetrahydrofolate Reductase Gene (MTHFR) 677C>T Polymorphism in Pediatric Cerebrovascular Disorders.
Migraine Disorders
Role of the ACE ID and MTHFR C677T polymorphisms in genetic susceptibility of migraine in a north Indian population.
Migraine Disorders
Search for correlations between genotypes and electrophysiological patterns in migraine: the MTHFR C677T polymorphism and visual evoked potentials.
Migraine Disorders
Testing of variants of the MTHFR and ESR1 genes in 1798 Finnish individuals fails to confirm the association with migraine with aura.
Migraine Disorders
The C677T polymorphism in MTHFR is not associated with migraine in Portugal.
Migraine Disorders
The effects of vitamin supplementation and MTHFR (C677T) genotype on homocysteine-lowering and migraine disability.
Migraine Disorders
The homozygous C677T mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for migraine.
Migraine Disorders
The methylenetetrahydrofolate reductase gene variant C677T influences susceptibility to migraine with aura.
Migraine Disorders
The Relationship Between Homocysteine and Genes of Folate-Related Enzymes in Migraine Patients.
Migraine Disorders
Thymidylate synthase promoter tandem repeat and MTHFD1 R653Q polymorphisms modulate the risk for migraine conferred by the MTHFR T677 allele.
Migraine Disorders
[Mutation of MTHFR gene as marker of endothelial dysfunction in patients diagnosed of migraine with aura.]
Migraine with Aura
Association of MTHFR gene polymorphisms with migraine in North Indian population.
Migraine with Aura
Association of the C677T and A1298C polymorphisms in the 5,10 methylenetetrahydrofolate reductase gene in patients with migraine risk.
Migraine with Aura
Association of the C677T polymorphism in the MTHFR gene with migraine: a meta-analysis.
Migraine with Aura
Effects of MTHFR gene polymorphism on the clinical and electrophysiological characteristics of migraine.
Migraine with Aura
Haplotype analysis of the folate-related genes MTHFR, MTRR, and MTR and migraine with aura.
Migraine with Aura
Influence of MTHFR genotype on contingent negative variation and MRI abnormalities in migraine.
Migraine with Aura
Interrelationships among the MTHFR 677C>T polymorphism, migraine, and cardiovascular disease.
Migraine with Aura
Lack of association between the MTHFR C677T variant and migraine with aura in an older population: Could selective survival play a role?
Migraine with Aura
Migraine mediates the influence of C677T MTHFR genotypes on ischemic stroke risk with a stroke-subtype effect.
Migraine with Aura
MTHFR 677C>T and ACE D/I Polymorphisms in Migraine: A Systematic Review and Meta-Analysis.
Migraine with Aura
Testing of variants of the MTHFR and ESR1 genes in 1798 Finnish individuals fails to confirm the association with migraine with aura.
Migraine with Aura
The C677T polymorphism in MTHFR is not associated with migraine in Portugal.
Migraine with Aura
The methylenetetrahydrofolate reductase gene variant C677T influences susceptibility to migraine with aura.
Migraine with Aura
[Mutation of MTHFR gene as marker of endothelial dysfunction in patients diagnosed of migraine with aura.]
Migraine without Aura
Association of the C677T and A1298C polymorphisms in the 5,10 methylenetetrahydrofolate reductase gene in patients with migraine risk.
Migraine without Aura
Migraine mediates the influence of C677T MTHFR genotypes on ischemic stroke risk with a stroke-subtype effect.
Mitochondrial Diseases
Inborn Errors of Metabolism Associated With Autism Spectrum Disorders: Approaches to Intervention.
Mouth Neoplasms
Are factor V and prothrombin mutations associated with increased risk of oral cancer?
Mouth Neoplasms
Association of MTHFR C677T and A1298C polymorphisms with oral cancer susceptibility: evidence from a meta-analysis.
Mouth Neoplasms
Folate intake, serum homocysteine and methylenetetrahydrofolate reductase (MTHFR) C677T genotype are not associated with oral cancer risk in Puerto Rico.
Mouth Neoplasms
Folate supplementation induces differential dose-dependent modulation of proliferative phenotypes among cancerous and noncancerous oral cell lines in vitro.
Mouth Neoplasms
Influence of methylenetetrahydrofolate reductase polymorphisms in oral cancer patients.
Mouth Neoplasms
Interaction between the MTHFR C677T Polymorphism and Alcohol: Impact on Oral Cancer Risk and Multiple DNA Methylation of Tumor-related Genes.
Mouth Neoplasms
Methylenetetrahydrofolate reductase (MTHFR) genotype, smoking habit, metastasis and oral cancer in Taiwan.
Mouth Neoplasms
Methylenetetrahydrofolate reductase polymorphism and minor increase of risk for oral cancer.
Mouth Neoplasms
Polymorphisms in methylenetetrahydrofolate reductase and cystathionine beta-synthase in oral cancer - a case-control study in southeastern Brazilians.
Mouth Neoplasms
Positive association between MTHFR C677T polymorphism and oral cancer risk: a meta-analysis.
Mouth Neoplasms
Tyms double (2R) and triple repeat (3R) confers risk for human oral squamous cell carcinoma.
Moyamoya Disease
The roles of methylenetetrahydrofolate reductase 677C>T and 1298A>C polymorphisms in moyamoya disease patients.
Mucocutaneous Lymph Node Syndrome
METHYLENETETRAHYDROFOLATE REDUCTASE C677T POLYMORPHISM IN PATIENTS WITH HENOCH-SCHÖNLEIN PURPURA.
Mucocutaneous Lymph Node Syndrome
Methylenetetrahydrofolate reductase polymorphism in Kawasaki disease.
Mucocutaneous Lymph Node Syndrome
Polymorphisms of methylenetetrahydrofolate reductase are not a risk factor for Kawasaki disease in the Korean population.
Mucositis
Association of genetic polymorphism in the folate metabolic pathway with methotrexate pharmacokinetics and toxicity in childhood acute lymphoblastic leukaemia and malignant lymphoma.
Mucositis
Association of MTHFR and ABCB1 polymorphisms with MTX-induced mucositis in Chinese paediatric patients with acute lymphoblastic leukaemia, lymphoma or osteosarcoma-A retrospective cohort study.
Mucositis
Associations between the C677T and A1298C polymorphisms of MTHFR and the toxicity of methotrexate in childhood malignancies: a meta-analysis.
Mucositis
DPYD*2A and MTHFR C677T predict toxicity and efficacy, respectively, in patients on chemotherapy with 5-fluorouracil for colorectal cancer.
Mucositis
Genetic variants associated with methotrexate-induced mucositis in cancer treatment: A systematic review and meta-analysis.
Mucositis
Identifying novel genes and biological processes relevant to the development of cancer therapy-induced mucositis: An informative gene network analysis.
Mucositis
Impact of thrombophilic gene mutations and graft-versus-host disease on thromboembolic complications after allogeneic hematopoietic stem-cell transplantation.
Mucositis
Influence of plasma methotrexate level and MTHFR genotype in Korean paediatric patients with acute lymphoblastic leukaemia.
Mucositis
Methotrexate-induced mucositis in acute leukemia patients is not associated with the MTHFR 677T allele in Mexico.
Mucositis
Mexican Childhood Acute Lymphoblastic Leukemia: A Pilot Study of the MDR1 and MTHFR Gene Polymorphisms and Their Associations with Clinical Outcomes.
Mucositis
MTHFR gene polymorphisms and methotrexate toxicity in adult patients with hematological malignancies: a meta-analysis.
Mucositis
Pharmacogenetic Variants in MTHFR Gene are Significant Predictors of Methotrexate Toxicities in Bangladeshi Patients With Acute Lymphoblastic Leukemia.
Mucositis
Role of folate status and methylenetetrahydrofolate reductase genotype on the toxicity and outcome of induction chemotherapy in children with acute lymphoblastic leukemia.
Multiple Chemical Sensitivity
Case-control study of genotypes in multiple chemical sensitivity: CYP2D6, NAT1, NAT2, PON1, PON2 and MTHFR.
Multiple Myeloma
Analysis of MTHFR polymorphisms and P16 methylation and their correlation with clinical-biological features of multiple myeloma.
Multiple Myeloma
Association between the MTHFR C677T polymorphism and risk of cancer: evidence from 446 case-control studies.
Multiple Myeloma
Meta-analysis of the association of MTHFR polymorphisms with multiple myeloma risk.
Multiple Myeloma
Methionine synthase genetic polymorphism MS A2756G alters susceptibility to follicular but not diffuse large B-cell non-Hodgkin's lymphoma or multiple myeloma.
Multiple Myeloma
Methylenetetrahydrofolate reductase 677CC normal genotype may protect against multiple myeloma.
Multiple Myeloma
Methylenetetrahydrofolate reductase genotype does not play a role in multiple myeloma pathogenesis.
Multiple Myeloma
Normal frequencies of the C677T genotypes on the methylenetetrahydrofolate reductase (MTHFR) gene among lymphoproliferative disorders but not in multiple myeloma.
Multiple Myeloma
Polymorphisms of methylenetetrahydrofolate reductase (MTHFR), methionine synthase (MTR), methionine synthase reductase (MTRR), and thymidylate synthase (TYMS) in multiple myeloma risk.
Multiple Myeloma
Should we screen patients for inherited thrombophilia before starting thalidomide?
Multiple Myeloma
[A new method for 5, 10-methylenetetrahydrofolate reductase single nucleotide polymorphisms genotyping used to study susceptibility of hematological malignancy]
Multiple Myeloma
[PROVISIONAL] The differential effects of the methylenetetrahydrofolate reductase polymorphisms (C677T and A1298C) on hematological malignancies among Latinos: a meta-analysis.
Multiple Sclerosis
A methylenetetrahydrofolate reductase gene polymorphism in multiple sclerosis.
Multiple Sclerosis
Association Between MTHFR Genetic Variants and Multiple Sclerosis in a Southern Iranian Population.
Multiple Sclerosis
Association of methylenetetrahydrofolate reductase A1298C polymorphism but not of C677T with multiple sclerosis in Tunisian patients.
Multiple Sclerosis
Association of methylenetetrahydrofolate reductase gene C677T polymorphism with multiple sclerosis in Turkish patients.
Multiple Sclerosis
Genetic investigation of methylenetetrahydrofolate reductase (MTHFR) and catechol-O-methyl transferase (COMT) in multiple sclerosis.
Multiple Sclerosis
Genetic variants of homocysteine metabolism and multiple sclerosis: a case-control study.
Multiple Sclerosis
Inflammatory Profile, Age of Onset, and the MTHFR Polymorphism in Patients with Multiple Sclerosis.
Multiple Sclerosis
Meta-analysis of associations between MTHFR and GST polymorphisms and susceptibility to multiple sclerosis.
Multiple Sclerosis
Relationship between genetic polymorphisms MTHFR (C677T, A1298C), MTR (A2756G) and MTRR (A66G) genes and multiple sclerosis: a case-control study.
Multiple Sclerosis
The variant methylenetetrahydrofolate reductase c.1298A>C (p.E429A) is associated with multiple sclerosis in a German case-control study.
Multiple Sclerosis, Relapsing-Remitting
Genetic variants of homocysteine metabolism and multiple sclerosis: a case-control study.
Muscle Cramp
Sacroiliitis and muscle cramps in a healthy young man: some spearhead on MTHFR mutations.
Muscle Hypotonia
Severe scoliosis in a patient with severe methylenetetrahydrofolate reductase deficiency.
Muscle Weakness
Mutations in MTHFR and POLG impaired activity of the mitochondrial respiratory chain in 46-year-old twins with spastic paraparesis.
Muscular Diseases
Betaine for treatment of homocystinuria caused by methylenetetrahydrofolate reductase deficiency.
Muscular Diseases
[Genotype and phenotype analysis of neonates with neonatal encephalopathy complicated with perinatal hypoxic event].
Musculoskeletal Pain
Epistasis between polymorphisms in COMT, ESR1, and GCH1 influences COMT enzyme activity and pain.
Myelitis
Longitudinal myelitis in patient with systemic lupus erythematosus, homozygous prothrombin G20210A and heterozygous MTHFR 677T.
Myelodysplastic Syndromes
MTHFR polymorphysms in myelodysplastic syndromes and therapy-related myeloid neoplasms.
Myelodysplastic Syndromes
MTHFR, TS and XRCC1 genetic variants may affect survival in patients with myelodysplastic syndromes treated with supportive care or azacitidine.
Myelodysplastic Syndromes
The genetics of pyoderma gangrenosum and implications for treatment: a systematic review.
Myocardial Infarction
A case report of myocardial infarction in young patient with a parental history of premature cardiovascular death: combination of prothrombotic gene mutations.
Myocardial Infarction
A common mutation in methylenetetrahydrofolate reductase gene is not a major risk of coronary artery disease or myocardial infarction.
Myocardial Infarction
A mutation in the methylenetetrahydrofolate reductase gene is not associated with increased risk for coronary artery disease or myocardial infarction.
Myocardial Infarction
Acute renal infarction associated with homozygous methylenetetrahydrofolate reductase mutation C677T and IgA beta-2-glycoprotein antibodies.
Myocardial Infarction
An association analysis between genetic polymorphisms of matrix metalloproteinase-3 and methylenetetrahydrofolate reductase and myocardial infarction in Japanese.
Myocardial Infarction
Association between factor V Leiden, prothrombin G20210A, and methylenetetrahydrofolate reductase C677T mutations and events of the arterial circulatory system: a meta-analysis of published studies.
Myocardial Infarction
Association Between Methylenetetrahydrofolate Reductase (MTHFR) C677T Polymorphism and Risk of Myocardial Infarction: Need for Clarification of Data in a Recent Meta-analysis.
Myocardial Infarction
Association Between Polymorphism of Methylenetetrahydrofolate Reductase (MTHFR) C677T and Risk of Myocardial Infarction: A Meta-analysis for 8,140 Cases and 10,522 Controls.
Myocardial Infarction
Association of C677T MTHFR and G20210A FII prothrombin polymorphisms with susceptibility to myocardial infarction.
Myocardial Infarction
Association of Genetic Variants of MTHFR, ENPP1, and ADIPOQ with Myocardial Infarction in Egyptian Patients.
Myocardial Infarction
Association of methylenetetrahydrofolate reductase gene polymorphism with carotid arterial wall thickening and myocardial infarction risk in NIDDM.
Myocardial Infarction
C667T and A1298C polymorphisms of methylenetetrahydrofolate reductase gene and susceptibility to myocardial infarction: A systematic review and meta-analysis.
Myocardial Infarction
C677T polymorphism of the 5,10 MTHFR gene in young Mexican subjects with ST-elevation myocardial infarction.
Myocardial Infarction
Case report: Acute myocardial infarction in a 32-year-old white male found to have antiphospholipid antibody syndrome and MTHFR mutation homozygosity.
Myocardial Infarction
Coexistence of prothrombic risk factors and its relation to left ventricular thrombus in acute myocardial infarction.
Myocardial Infarction
Combination of factor V Leiden and MTHFR mutations in myocardial infarction.
Myocardial Infarction
Common polymorphisms and cardiovascular factors in patients with myocardial infarction of Costa Rica.
Myocardial Infarction
Compound heterozygous MTHFR (C677T and A1298C) variants and anterior STEMI: cause or bystander?
Myocardial Infarction
D allele of the angiotensin-converting enzyme gene is a risk factor for secondary cardiac events after myocardial infarction.
Myocardial Infarction
Factor V G1691A, apo E4 allele, hyperhomocysteinemia and MTHFR C677T in a young patient with myocardial infarction.
Myocardial Infarction
Folate, homocysteine levels, methylenetetrahydrofolate reductase (MTHFR) 677C --> T variant, and the risk of myocardial infarction in young women: effect of female hormones on homocysteine levels.
Myocardial Infarction
Gene polymorphisms of homocysteine metabolism-related enzymes in Chinese patients with occlusive coronary artery or cerebral vascular diseases.
Myocardial Infarction
Genetic analysis of thermolabile methylenetetrahydrofolate reductase as a risk factor for myocardial infarction.
Myocardial Infarction
Genetic polymorphism of 5,10-methylenetetrahydrofolate increases risk of myocardial infarction and is correlated to elevated levels of homocysteine in the Japanese general population.
Myocardial Infarction
Genetic polymorphism of 5,10-MTHFR reductase gene in offspring of patients with myocardial infarction.
Myocardial Infarction
Genetic polymorphism of methylenetetrahydrofolate reductase and myocardial infarction. A case-control study.
Myocardial Infarction
Genetic polymorphisms and the risk of myocardial infarction in patients under 45 years of age.
Myocardial Infarction
Genetic polymorphisms, Biochemical Factors, and Conventional Risk Factors in Young and Elderly North Indian Patients With Acute Myocardial Infarction.
Myocardial Infarction
Homocyst(e)ine and the C677T mutation of methylenetetrahydrofolate reductase in survivors of premature myocardial infarction.
Myocardial Infarction
Homocysteine levels and MTHFR polymorphisms in young patients with acute myocardial infarction: a case control study.
Myocardial Infarction
Homozygosity for the C677-->T mutation of 5,10-methylenetetrahydrofolate reductase and total plasma homocyst(e) ine are not associated with greater than normal risk of a first myocardial infarction in northern Sweden.
Myocardial Infarction
Homozygosity of the TT methylenetetrahydrofolate reductase C677T genotype is an independent long-term predictor of cardiac death in patients with premature myocardial infarction.
Myocardial Infarction
Lack of association of methylenetetrahydrofolate reductase 677C>T mutation with coronary artery disease in a Pakistani population.
Myocardial Infarction
Meta-analysis of MTHFR 677C->T polymorphism and coronary heart disease: does totality of evidence support causal role for homocysteine and preventive potential of folate?
Myocardial Infarction
Methylenetetrahydrofolate reductase gene polymorphism and risk of premature myocardial infarction.
Myocardial Infarction
Methylenetetrahydrofolate Reductase Polymorphism and Premature Coronary Artery Disease.
Myocardial Infarction
Methylenetetrahydrofolate reductase polymorphism, plasma folate, homocysteine, and risk of myocardial infarction in US physicians.
Myocardial Infarction
Methylentetrahydrofolate Reductase and Nitric Oxide Synthase Polymorphism in Patients with Atherosclerosis and Diabetes.
Myocardial Infarction
Migraine and coronary artery disease: an open study on the genetic polymorphism of the 5, 10 methylenetetrahydrofolate (MTHFR) and angiotensin I-converting enzyme (ACE) genes.
Myocardial Infarction
MTHFR (Ala 222 Val) polymorphism and AMI in patients with type II diabetes mellitus.
Myocardial Infarction
MTHFR C677T Polymorphism and Its Relationship to Myocardial Infarction in the Eastern Black Sea Region of Turkey.
Myocardial Infarction
MTHFR Gene polymorphisms, B-vitamins and hyperhomocystinemia in young and middle-aged acute myocardial infarction patients.
Myocardial Infarction
MTHFR polymorphism and risk of periprocedural myocardial infarction after coronary stenting.
Myocardial Infarction
Mutations in the genes regulating methylene tetrahydrofolate reductase (MTHFR C-->T677) and cystathione beta-synthase (CBS G-->A919, CBS T-->c833) are not associated with myocardial infarction in African Americans.
Myocardial Infarction
Myocardial infarction and venous thrombosis in a 42-year old woman with heterozygous methylenetetrahydrofolate reductase (MTHRF) gene mutation, hyperhomocysteinemia, and protein C deficiency.
Myocardial Infarction
Myocardial Infarction in a Newborn Heterozygous for the MTHFR C677T Mutation.
Myocardial Infarction
Myocardial infarction in young women in relation to plasma total homocysteine, folate, and a common variant in the methylenetetrahydrofolate reductase gene.
Myocardial Infarction
No evidence of association between prothrombotic gene polymorphisms and the development of acute myocardial infarction at a young age.
Myocardial Infarction
Polymorphisms in MTHFR, MS and CBS genes and premature acute myocardial infarction in a Pakistani population.
Myocardial Infarction
Prevalence of myocardial infarction is related to hyperhomocysteinemia but not influenced by C677T methylenetetrahydrofolate reductase and A2756G methionine synthase polymorphisms in diabetic and non-diabetic subjects.
Myocardial Infarction
Prothrombotic gene polymorphisms and plasma factors in young north Indian survivors of acute myocardial infarction.
Myocardial Infarction
Prothrombotic genetic risk factors in young survivors of myocardial infarction.
Myocardial Infarction
Recurrent Myocardial Infarction Despite Normal C-reactive Protein in a Patient with Behcet's Disease and Compound Heterozygous Methylenetetrahydrofolate Reductase (MTHFR) Mutations (C677T and A1298C).
Myocardial Infarction
Reply: Association Between Methylenetetrahydrofolate Reductase (MTHFR) C677T Polymorphism and Risk of Myocardial Infarction: Need for Clarification of Data in a Recent Meta-analysis.
Myocardial Infarction
Risk factors and methylenetetrahydrofolate reductase gene polymorphisms in a young South African Indian-based population with acute myocardial infarction.
Myocardial Infarction
Role of methylenetetrahydrofolate reductase 677C->T polymorphism in the development of premature myocardial infarction.
Myocardial Infarction
Sequence Variation of the Methylene Tetrahydrofolate Reductase Gene (677C>T and 1298?A>C) and Traditional Risk Factors in a South Indian Population.
Myocardial Infarction
ST-elevation myocardial infarction, pulmonary embolism, and cerebral ischemic stroke in a patient with critically low levels of natural anticoagulants.
Myocardial Infarction
Successful conservative treatment of myocardial infarction in a teenager with MTHFR mutation.
Myocardial Infarction
Synergistic effects of prothrombotic polymorphisms and atherogenic factors on the risk of myocardial infarction in young males.
Myocardial Infarction
The C677T mutation of the methylenetetrahydrofolate reductase gene is not associated with the risk of coronary artery disease or venous thrombosis among Chinese in Taiwan.
Myocardial Infarction
The genotype interactions of methylenetetrahydrofolate reductase and renin-angiotensin system genes are associated with myocardial infarction.
Myocardial Infarction
The methylenetetrahydrofolate reductase (MTHFR) 677C-->T mutation and cardiovascular risk--A case of ischemic stroke and acute myocardial infarction.
Myocardial Infarction
The role and importance of gene polymorphisms in the development of atherosclerosis.
Myocardial Infarction
The rs1801133 polymorphism of methylenetetrahydrofolate reductase gene- the association with 5-year survival in patients with ST-elevation myocardial infarction.
Myocardial Infarction
The TT genotype of the methylenetetrahydrofolate reductase C677T gene polymorphism is associated with the extent of coronary atherosclerosis in patients at high risk for coronary artery disease.
Myocardial Infarction
[Allelic variants of genes: angiotensin I-converting enzyme (ACE), angiotensin-II type 1 receptor (AT1R), methylenetetrahydrofolate reductase and left ventricular mass in patients with myocardial infarction]
Myocardial Infarction
[Association of methylenetetrahydrofolate reductase gene polymorphism with the development of myocardial infarction in patients with type 2 diabetes].
Myocardial Infarction
[C677T gene polymorphism of methylenetetrahydrofolate reductase (MTHFR) in patients with myocardial infarction]
Myocardial Infarction
[Gene Polymorphism of 5, 10-methylenetetrahydrofolate reductase as a coronary risk factor]
Myocardial Infarction
[Polymorphism of genes coding for angiotensin I converting enzyme and methylenetetrahydrofolate reductase in patients with ischemic heart disease]
Myocardial Infarction
[Study on homocysteine metabolism related enzymes gene mutations in Chinese patients with ischemic cardiovascular and cerebrovascular diseases]
Myocardial Ischemia
Epistasis analysis of metabolic genes polymorphisms associated with ischemic heart disease in Yucatan.
Myocardial Ischemia
Family history, plasma homocysteine, and age at onset of symptoms of myocardial ischemia in patients with different methylenetetrahydrofolate reductase genotypes.
Myocardial Ischemia
Plasma homocysteine, methylenetetrahydrofolate reductase genotypes, and age at onset of symptoms of myocardial ischemia.
Myocardial Ischemia
Polymorphisms C677T and A1298C of MTHFR Gene: Homocysteine Levels and Prothrombotic Biomarkers in Coronary and Pulmonary Thromboembolic Disease.
Myocardial Ischemia
[Distributions of polymorphisms of genes of some components of hemostasis in patients with ischemic heart disease]
Myocardial Ischemia
[Polymorphism of genes coding for angiotensin I converting enzyme and methylenetetrahydrofolate reductase in patients with ischemic heart disease]
Myoclonic Epilepsies, Progressive
Severe 5,10-methylenetetrahydrofolate reductase deficiency and two MTHFR variants in an adolescent with progressive myoclonic epilepsy.
nadh:ubiquinone reductase (h+-translocating) deficiency
Recessive spastic paraparesis associated with complex I deficiency due to MTHFR mutations.
Nasopharyngeal Carcinoma
Polymorphisms of methylenetetrahydrofolate reductase are associated with a high risk of nasopharyngeal carcinoma in a smoking population from Southern China.
Neoplasm Metastasis
Genetic polymorphisms and response to 5-fluorouracil, doxorubicin and cyclophosphamide chemotherapy in breast cancer patients.
Neoplasm Metastasis
Genetic variants in 3'-UTRs of methylenetetrahydrofolate reductase (MTHFR) predict colorectal cancer susceptibility in Koreans.
Neoplasm Metastasis
K-Ras mutations and treatment outcome in colorectal cancer patients receiving exclusive fluoropyrimidine therapy.
Neoplasm Metastasis
Methylenetetrahydrofolate reductase (MTHFR) genotype, smoking habit, metastasis and oral cancer in Taiwan.
Neoplasm Metastasis
Methylenetetrahydrofolate reductase C677T gene polymorphism in osteosarcoma and chondrosarcoma patients.
Neoplasm Metastasis
Methylenetetrahydrofolate reductase gene polymorphisms and response to fluorouracil-based treatment in advanced colorectal cancer patients.
Neoplasm Metastasis
The 677C > T mutation in 5,10-methylenetetrahydrofolate reductase and colorectal cancer risk.
Neoplasm Metastasis
Which gene is a dominant predictor of response during FOLFOX chemotherapy for the treatment of metastatic colorectal cancer, the MTHFR or XRCC1 gene?
Neoplasm Metastasis
[Association between genetic variations in methylenetetrahydrofolate reductase and risk of colorectal cancer in a Chinese population]
Neoplasm, Residual
Germline genetic variations in methotrexate candidate genes are associated with pharmacokinetics, toxicity, and outcome in childhood acute lymphoblastic leukemia.
Neoplasms
5,10-methylenetetrahydrofolate reductase 677 and 1298 polymorphisms, folate intake, and microsatellite instability in colon cancer.
Neoplasms
5,10-Methylenetetrahydrofolate reductase polymorphisms and pharmacogenetics: a new role of single nucleotide polymorphisms in the folate metabolic pathway in human health and disease.
Neoplasms
667C>T and 1298A>C polymorphisms of MTHFR do not predict response to methotrexate in patients with gestational trophoblastic neoplasia.
Neoplasms
A common variant of the methylenetetrahydrofolate reductase gene (1p36) is associated with an increased risk of cancer.
Neoplasms
A Daily Dose of 5 mg Folic Acid for 90 Days Is Associated with Increased Serum Unmetabolized Folic Acid and Reduced Natural Killer Cell Cytotoxicity in Healthy Brazilian Adults.
Neoplasms
A haplotype of the methylenetetrahydrofolate reductase gene predicts poor tumor response in rectal cancer patients receiving preoperative chemoradiation.
Neoplasms
A lower degree of PBMC L1 methylation in women with lower folate status may explain the MTHFR C677T polymorphism associated higher risk of CIN in the US post folic acid fortification era.
Neoplasms
A methylenetetrahydrofolate reductase polymorphism is associated with expression of p16 in human lung cancer.
Neoplasms
A novel single nucleotide polymorphism of the human methylenetetrahydrofolate reductase gene in Japanese individuals.
Neoplasms
A polymorphism in the methylenetetrahydrofolate reductase gene predisposes to colorectal cancers with microsatellite instability.
Neoplasms
A prospective study of methylenetetrahydrofolate reductase and methionine synthase gene polymorphisms, and risk of colorectal adenoma.
Neoplasms
A retrospective comparative exploratory study on two Methylentetrahydrofolate Reductase (MTHFR) polymorphisms in esophagogastric cancer: the A1298C MTHFR polymorphism is an independent prognostic factor only in neoadjuvantly treated gastric cancer patients.
Neoplasms
A systematic review and meta-analysis of somatic and germline DNA sequence biomarkers of esophageal cancer survival, therapy response and stage.
Neoplasms
Aberrant DNA Methylation associated with MTHFR C677T Genetic Polymorphism in cutaneous squamous cell carcinoma in renal transplant patients.
Neoplasms
Aberrant DNA Methylation of P16, MGMT, and hMLH1 Genes in Combination with MTHFR C677T Genetic Polymorphism in gastric cancer.
Neoplasms
Aberrant DNA Methylation of P16, MGMT, hMLH1 and hMSH2 Genes in Combination with the MTHFR C677T Genetic Polymorphism in Gastric Cancer.
Neoplasms
Aberrant DNA methylation of the P16, MGMT, and hMLH1 genes in combination with the methylenetetrahydrofolate reductase C677T genetic polymorphism and folate intake in gastric cancer.
Neoplasms
ACE I/D sequence variants but not MTHFR C677T, is strongly linked to malignant glioma risk and its variant DD genotype may act as a promising predictive biomarker for overall survival of glioma patients.
Neoplasms
Allelic variations in 5, 10-methylenetetrahydrofolate reductase gene and susceptibility to cervical cancer in Indian women.
Neoplasms
Analysis of the methylation patterns of the p16 (INK4A) , p15 (INK4B) , and APC genes in gastric adenocarcinoma patients from a Brazilian population.
Neoplasms
Analysis of the MTHFR (methylenetetrahydrofolate reductase) 677 C>T and 1298 A>C polymorphisms in BCR-ABL-negative myeloproliferative neoplasms.
Neoplasms
Antisense inhibition of methylenetetrahydrofolate reductase reduces cancer cell survival in vitro and tumor growth in vivo.
Neoplasms
Antisense inhibition of methylenetetrahydrofolate reductase reduces survival of methionine-dependent tumour lines.
Neoplasms
Are the methylenetetrahydrofolate reductase 1298 and 677 gene polymorphisms related to optic glioma and hamartoma risk in neurofibromatosis type 1 patients?
Neoplasms
Association between 11 genetic polymorphisms in folate-metabolising genes and head and neck cancer risk.
Neoplasms
Association between methylenetetrahydrofolate reductase gene rs1801131 A/C polymorphism and urinary tumors' susceptibility.
Neoplasms
Association between methylenetetrahydrofolate reductase polymorphisms, alcohol intake and oropharyngolaryngeal carcinoma in northern Italy.
Neoplasms
Association between MTHFR C677T, MTHFR A1298C and MS A2756G polymorphisms and risk of cervical intraepithelial neoplasia II/III and cervical cancer: A meta-analysis.
Neoplasms
Association between MTHFR Gene Polymorphism and the Risk of Ovarian Cancer: A Meta-analysis of the Literature.
Neoplasms
Association between MTHFR Gene Polymorphisms and the Risk of Autism Spectrum Disorders: A Meta-Analysis.
Neoplasms
Association between polymorphisms of folate-metabolizing enzymes and risk of prostate cancer.
Neoplasms
Association between the 1793G> A MTHFR polymorphism and sporadic colorectal cancer in Iran.
Neoplasms
Association between the methylenetetrahydrofolate reductase polymorphisms and risk of acute lymphoblastic leukemia in serbian children.
Neoplasms
Association between the MTHFR A1298C polymorphism and risk of cancer: evidence from 265 case-control studies.
Neoplasms
Association between the MTHFR C677T polymorphism and risk of cancer: evidence from 446 case-control studies.
Neoplasms
Association of Folate and Vitamins Involved in the 1-Carbon Cycle with Polymorphisms in the Methylenetetrahydrofolate Reductase Gene (MTHFR) and Global DNA Methylation in Patients with Colorectal Cancer.
Neoplasms
Association of Methylenetetrahydrafolate Reductase Gene Polymorphism (MTHFR) in Patients with Gallbladder Cancer.
Neoplasms
Association of methylenetetrahydrofolate reductase and thymidylate synthase promoter polymorphisms with genetic susceptibility to esophageal and cardia cancer in a Chinese high-risk population.
Neoplasms
Association of methylenetetrahydrofolate reductase gene polymorphisms & colorectal cancer in India.
Neoplasms
Association of methylenetetrahydrofolate reductase gene polymorphisms and sex-specific survival in patients with metastatic colon cancer.
Neoplasms
Association of MTHFR 677C>T, 1298A>C and MTR 2756A>G Polymorphisms with Risk of Retinoblastoma.
Neoplasms
Association of MTHFR 677C>T Polymorphism with Susceptibility to Ovarian and Cervical Cancers: A Systematic Review and Meta-Analysis.
Neoplasms
Association of Polymorphisms in Genes Involved in One-Carbon Metabolism with MTHFR Methylation Levels.
Neoplasms
Association of polymorphisms MTHFR C677T and A1298C with risk of colorectal cancer, genetic and epigenetic characteristic of tumors, and response to chemotherapy.
Neoplasms
Association of the 5,10-methylenetetrahydrofolate reductase (MTHFR C677T and A1298C) polymorphisms in Korean patients with adult acute lymphoblastic leukemia.
Neoplasms
Association of the 677C -->T polymorphism in the MTHFR gene with colorectal cancer in Mexican patients.
Neoplasms
Association of the C677T polymorphism in the methylenetetrahydrofolate reductase gene with breast cancer in a Mexican population.
Neoplasms
Association of the functional polymorphism C677T in the methylenetetrahydrofolate reductase gene with colorectal, thyroid, breast, ovarian, and cervical cancers.
Neoplasms
Association of the MTHFR Gene C677T Polymorphism with Breast Cancer in a Turkish Population.
Neoplasms
Association of the polymorphisms of MTHFR C677T, VDR C352T, and MPO G463A with risk for esophageal squamous cell dysplasia and carcinoma.
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Associations between family history of cancer and genes coding for metabolizing enzymes (United States).
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Associations between methylenetetrahydrofolate reductase polymorphisms and hepatocellular carcinoma risk in Chinese population.
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Associations between the C677T and A1298C polymorphisms of MTHFR and the toxicity of methotrexate in childhood malignancies: a meta-analysis.
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Associations of plasma homocysteine and the methylenetetrahydrofolate reductase C677T polymorphism with carotid intima media thickness among South Asian, Chinese and European Canadians.
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Breast cancer risk, dietary intake, and methylenetetrahydrofolate reductase (MTHFR)single nucleotide polymorphisms.
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C677T gene polymorphism of methylenetetrahydrofolate reductase (MTHFR) in meningiomas and high-grade gliomas.
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CDA and MTHFR polymorphisms are associated with clinical outcomes in gastroenteric cancer patients treated with capecitabine-based chemotherapy.
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Chapter 13 methylenetetrahydrofolate reductase, common polymorphisms, and relation to disease.
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Colorectal carcinomas with microsatellite instability display increased thymidylate synthase gene expression levels.
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Common polymorphisms in methylenetetrahydrofolate reductase gene are associated with risks of cervical intraepithelial neoplasia and cervical cancer in women with low serum folate and vitamin B12.
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Comparison of Capillary Electrophoresis, AGE, and PAGE for MTHFR Polymorphism Analysis in FFPE Cervical Samples.
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Comparison of standard PCR and the LightCycler technique to determine the thrombophilic mutations: an efficiency and cost study.
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Comprehensive analysis of Methylenetetrahydrofolate reductase C677T in younger acute lymphoblastic leukemia patients: A single-center experience.
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Comprehensive evaluation of one-carbon metabolism pathway gene variants and renal cell cancer risk.
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Dietary folate intake in combination with MTHFR C677T genotype and promoter methylation of tumor suppressor and DNA repair genes in sporadic colorectal adenomas.
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Different roles of MTHFR C677T and A1298C polymorphisms in colorectal adenoma and colorectal cancer: a meta-analysis.
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Dihydropyrimidine Dehydrogenase 85T>C Mutation Is Associated With Ocular Toxicity of 5-Fluorouracil: A Case Report.
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DNA methylation changes associated with cancer risk factors and blood levels of vitamin metabolites in a prospective study.
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DNA methylation changes associated with risk factors in tumors of the upper aerodigestive tract.
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DNA methylation profiles in diffuse large B-cell lymphoma and their relationship to gene expression status.
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Easy detection of 5,10-methylenetetrahydrofolate reductase 1298A/C genotype by mutagenically separated PCR assay.
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Effect of cystathionine beta-synthase variant 844ins68bp and methylenetetrahydrofolate reductase A1298C polymorphisms in xenografts on 5-FU efficacy and doubling time.
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Effect of folic acid supplementation on cancer risk among adults with hypertension in China: A randomized clinical trial.
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Effect of the methylenetetrahydrofolate reductase C677T polymorphism on chemosensitivity of colon and breast cancer cells to 5-fluorouracil and methotrexate.
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Effect of the methylenetetrahydrofolate reductase gene C677T polymorphism on C-erbB-2 methylation status and its association with cancer.
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Effects of methylenetetrahydrofolate reductase single-nucleotide polymorphisms on breast, cervical, ovarian, and endometrial cancer susceptibilities.
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Effects of the MTHFR C677T Polymorphism on Prostate Specific Antigen and Prostate Cancer.
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Endoplasmic reticulum stress increases the expression of methylenetetrahydrofolate reductase through the IRE1 transducer.
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Epigenetics in Clinical Practice: Characterizing Patient and Provider Experiences with MTHFR Polymorphisms and Methylfolate.
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Epithelial-Mesenchymal Transition and MicroRNAs in Colorectal Cancer Chemoresistance to FOLFOX.
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Esophageal and gastric cardia cancer risk and folate- and vitamin B(12)-related polymorphisms in Linxian, China.
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Evaluation of the contribution of methylenetetrahydrofolate reductase genotypes to Taiwan breast cancer.
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Evaluation of the MTHFR C677T Polymorphism as a Risk Factor for Colorectal Cancer in Asian Populations.
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Expression and clinical significance of methylenetetrahydrofolate reductase in patients with colorectal cancer.
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Fission Yeast Methylenetetrahydrofolate Reductase Ensures Mitotic and Meiotic Chromosome Segregation Fidelity.
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Folate intake and methylenetetrahydrofolate reductase gene polymorphisms as predictive and prognostic biomarkers for ovarian cancer risk.
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Folate intake, methylenetetrahydrofolate reductase polymorphisms, and breast cancer risk in women from the Malmö Diet and Cancer cohort.
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Folate pathway genetic polymorphisms and susceptibility of central nervous system tumors in Thai children.
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Folate restriction and methylenetetrahydrofolate reductase 677T polymorphism decreases adoMet synthesis via folate-dependent remethylation in human-transformed lymphoblasts.
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Folate status among patients with non-small cell lung cancer: a case-control study.
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Folate status, genomic DNA hypomethylation, and risk of colorectal adenoma and cancer: a case control study.
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Folate, homocysteine, interleukin-6, and tumor necrosis factor alfa levels, but not the methylenetetrahydrofolate reductase C677T polymorphism, are risk factors for schizophrenia.
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Folate, methyl-related nutrients, alcohol, and the MTHFR 677C-->T polymorphism affect cancer risk: intake recommendations.
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Food Intervention with Folate Reduces TNF-? and Interleukin Levels in Overweight and Obese Women with the MTHFR C677T Polymorphism: A Randomized Trial.
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Frequencies of poor metabolizer alleles of 12 pharmacogenomic actionable genes in Punjabi Sikhs of Indian Origin.
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FV Leiden mutation and risk of recurrent venous thromboembolism in Serbian population.
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Gender-specific association of methylenetetrahydrofolate reductase genotype and haplotype with the aggressiveness and prognosis of clear cell renal cell carcinoma in Japanese patients.
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Gene polymorphisms involved in folate and methionine metabolism and increased risk of sporadic colorectal adenocarcinoma.
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Gene polymorphisms of folate metabolizing enzymes and the risk of gastric cancer.
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Gene-Specific Methylation Analysis in Thymomas of Patients with Myasthenia Gravis.
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Genetic and epigenetic variants in the MTHFR gene are not associated with non-Hodgkin lymphoma.
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Genetic and epigenetic variation in the DNMT3B and MTHFR genes and colorectal adenoma risk.
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Genetic polymorphisms in folate- metabolizing enzymes and risk of gastroesophageal cancers: a potential nutrient-gene interaction in cancer development.
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Genetic polymorphisms in methylenetetrahydrofolate reductase and thymidylate synthase and risk of pancreatic cancer.
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Genetic polymorphisms in MTHFR 677 and 1298, GSTM1 and T1, and metabolism of arsenic.
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Genetic polymorphisms of methylenetetrahydrofolate reductase and promoter methylation of MGMT and FHIT genes in diffuse large B cell lymphoma risk in Middle East.
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Genetic polymorphisms of the methylenetetrahydrofolate reductase gene, plasma folate levels and breast cancer susceptibility: a case-control study in Taiwan.
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Genetic variants in 3'-UTRs of methylenetetrahydrofolate reductase (MTHFR) predict colorectal cancer susceptibility in Koreans.
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Genetic variation in the folate metabolic pathway and risk of childhood leukemia.
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Genetic variations in MTHFR and gastric cardia adenocarcinoma susceptibility in the Chinese Han population.
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Genome-wide Hypomethylation in Human Glioblastomas Associated with Specific Copy Number Alteration, Methylenetetrahydrofolate Reductase Allele Status, and Increased Proliferation.
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Genomic DNA hypomethylation, a characteristic of most cancers, is present in peripheral leukocytes of individuals who are homozygous for the C677T polymorphism in the methylenetetrahydrofolate reductase gene.
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Geographical and ethnic distribution of MTHFR gene polymorphisms and their associations with diseases among Chinese population.
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Green tea intake, MTHFR/TYMS genotype and breast cancer risk: the Singapore Chinese Health Study.
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Heterozygote advantage of methylenetetrahydrofolate reductase polymorphisms on clinical outcomes in advanced non-small cell lung cancer (NSCLC) patients treated with platinum-based chemotherapy.
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High resolution array comparative genomic hybridization identifies copy number alterations in diffuse large B-cell lymphoma that predict response to immuno-chemotherapy.
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High-resolution melting curve analysis for genotyping of common SNP in MTHFR gene using fixed-cell suspension.
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How folate metabolism affects colorectal cancer development and treatment; a story of heterogeneity and pleiotropy.
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Hyperhomocysteinemia and MTHFR C677T polymorphism in patients with portal vein thrombosis complicating liver cirrhosis.
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Hyperhomocysteinemia, methylenetetrahydrofolate reductase c.677C>T polymorphism, and risk of cancer: cross-sectional and prospective studies and meta-analyses of 75,000 cases and 93,000 controls.
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Identification of a panel of sensitive and specific DNA methylation markers for squamous cell lung cancer.
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Identification of microRNAs associated with abdominal aortic aneurysms and peripheral arterial disease.
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Immunohistochemical and genetic prognostic factors of neoadjuvant chemoradiotherapy effic?cy in personalized treatment of local advanced rectal cancer.
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Impact of methylenetetrahydrofolate reductase polymorphisms and folate intake on the risk of gastric cancer and their association with Helicobacter pylori infection and tumor site.
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Impact of thrombophilic genes mutations on thrombosis risk in Egyptian nonmetastatic cancer patients.
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Implication of the folate-methionine metabolism pathways in susceptibility to follicular lymphomas.
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Improved real-time multiplex polymerase chain reaction detection of methylenetetrahydrofolate reductase (MTHFR) 677C>T and 1298A>C polymorphisms using nearest neighbor model-based probe design.
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In human alleles specific variation of MTHFR C677T and A1298C associated "risk factor" for the development of ovarian cancer.
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Increased breast cancer risk at high plasma folate concentrations among women with the MTHFR 677T allele.
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Influence of cancer-related gene polymorphisms on clinicopathological features in colorectal cancer.
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Influence of MTHFR Genetic Background on p16 and MGMT Methylation in Oral Squamous Cell Cancer.
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Interaction among folate, riboflavin, genotype, and cancer, with reference to colorectal and cervical cancer.
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Interaction between alcohol consumption and methylenetetrahydrofolate reductase polymorphisms in thyroid cancer risk: National Cancer Center cohort in Korea.
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Interaction of methylenetetrahydrofolate reductase genotype and smoking habit in Taiwanese lung cancer patients.
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Interactions Between MTHFR C677T - A1298C Variants and Folic Acid Deficiency Affect Breast Cancer Risk in a Chinese Population.
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Intraindividual somatic variations in MTHFR gene polymorphisms in relation to colon cancer.
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Involvement of gene polymorphisms of the folate pathway enzymes in gene expression and anticancer drug sensitivity using the NCI-60 panel as a model.
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Is genetic screening necessary for determining the possibility of venous thromboembolism in cancer patients?
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K-Ras mutations and treatment outcome in colorectal cancer patients receiving exclusive fluoropyrimidine therapy.
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Lack of association between methylenetetrahydrofolate reductase C677T polymorphism, HPV infection and cervical intraepithelial neoplasia in Brazilian women.
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Lack of association between the C677T MTHFR polymorphism and colorectal hyperplastic polyps.
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Lack of replication of association findings in complex disease: an analysis of 15 polymorphisms in prior candidate genes for sporadic Alzheimer's disease.
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Loss of heterozygosity at the 5,10-methylenetetrahydrofolate reductase locus in human ovarian carcinomas.
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Loss of heterozygosity of methylenetetrahydrofolate reductase in colon carcinomas.
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Low dietary folate initiates intestinal tumors in mice, with altered expression of G2-M checkpoint regulators polo-like kinase 1 and cell division cycle 25c.
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MAOA, MTHFR, and TNF-? genes polymorphisms and personality traits in the pathogenesis of migraine.
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Meta-analyses of the methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and risk of head and neck and lung cancer.
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Meta-Prediction of MTHFR Gene Polymorphism Mutations and Associated Risk for Colorectal Cancer.
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Methyl group metabolism gene polymorphisms and susceptibility to prostatic carcinoma.
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Methylene tetrahydrofolate reductase (MTHFR) gene polymorphisms in chronic myeloid leukemia: an Egyptian study.
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Methylene tetrahydrofolate reductase genotype modifies the chemopreventive effect of folate in colorectal adenoma, but not colorectal cancer.
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Methylenetetrahydrofolate reductase (MTHFR) and methionine synthase reductase (MTRR) gene polymorphisms as risk factors for hepatocellular carcinoma in a Korean population.
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Methylenetetrahydrofolate reductase (MTHFR) and susceptibility for (pre)neoplastic cervical disease.
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Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism: epidemiology, metabolism and the associated diseases.
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Methylenetetrahydrofolate Reductase (MTHFR) Gene C677T, A1298C and G1793A Polymorphisms: Association with Risk for Clear Cell Renal Cell Carcinoma and Tumour Behaviour in Men.
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Methylenetetrahydrofolate reductase (MTHFR) polymorphism increases the risk of cervical intraepithelial neoplasia.
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Methylenetetrahydrofolate reductase (MTHFR) polymorphisms and promoter methylation in cervical oncogenic lesions and cancer.
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Methylenetetrahydrofolate reductase (MTHFR) polymorphisms and risk of molecularly defined subtypes of childhood acute leukemia.
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Methylenetetrahydrofolate reductase (MTHFR) variants and bladder cancer: a population-based case-control study.
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Methylenetetrahydrofolate reductase (MTHFR) variants and fluorouracil-based treatments in colorectal cancer.
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Methylenetetrahydrofolate reductase 677 C-->T polymorphism and risk of proximal colon cancer in north Italy.
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Methylenetetrahydrofolate reductase 677C->T polymorphism and folate status affect one-carbon incorporation into human DNA deoxynucleosides.
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Methylenetetrahydrofolate Reductase A1298C Polymorphism and Breast Cancer Risk: A Meta-analysis of 33 Studies.
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Methylenetetrahydrofolate reductase and thymidylate synthase polymorphisms are not associated with breast cancer risk or phenotype.
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Methylenetetrahydrofolate reductase C667T polymorphism is associated with increased risk of coronary artery disease in a Chinese population.
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Methylenetetrahydrofolate reductase C677T and A1298C gene polymorphisms in oral squamous cell carcinoma in south-east Iran.
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Methylenetetrahydrofolate reductase C677T and A1298C gene variants in adult non-Hodgkin's lymphoma patients: association with toxicity and survival.
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Methylenetetrahydrofolate reductase C677T gene polymorphism in osteosarcoma and chondrosarcoma patients.
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Methylenetetrahydrofolate reductase C677T genotype affects promoter methylation of tumor-specific genes in sporadic colorectal cancer through an interaction with folate/vitamin B12 status.
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Methylenetetrahydrofolate reductase C677T is not associated with expression of pyrimidine metabolic enzyme genes in colorectal cancer.
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Methylenetetrahydrofolate reductase C677T polymorphism and susceptibility to cervical cancer and cervical intraepithelial neoplasia: a meta-analysis.
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Methylenetetrahydrofolate reductase gene polymorphisms and lung cancer: a meta-analysis.
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Methylenetetrahydrofolate reductase gene polymorphisms and response to fluorouracil-based treatment in advanced colorectal cancer patients.
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Methylenetetrahydrofolate reductase gene polymorphisms in 13 Chinese ethnic populations.
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Methylenetetrahydrofolate reductase gene polymorphisms: association with risk for pediatric acute lymphoblastic leukemia in north Indians.
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Methylenetetrahydrofolate reductase genotype does not play a role in multiple myeloma pathogenesis.
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Methylenetetrahydrofolate reductase genotypes and haplotypes associated with susceptibility to colorectal cancer in an eastern Chinese Han population.
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Methylenetetrahydrofolate reductase polymorphism C677T is not associated to the risk of cervical dysplasia.
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Methylenetetrahydrofolate reductase polymorphism in advanced colorectal cancer: a novel genomic predictor of clinical response to fluoropyrimidine-based chemotherapy.
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Methylenetetrahydrofolate reductase polymorphism, diet, and breast cancer in Korean women.
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Methylenetetrahydrofolate reductase polymorphisms and risk of squamous cell carcinoma of the head and neck: a case-control analysis.
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Methylenetetrahydrofolate reductase polymorphisms and susceptibility to gastric cancer in Chinese populations: a meta-analysis.
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Methylenetetrahydrofolate reductase polymorphisms modify BRCA1-associated breast and ovarian cancer risks.
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Methylenetetrahydrofolate reductase polymorphisms, folate, and cancer risk: a paradigm of gene-nutrient interactions in carcinogenesis.
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Molecular phylogenetic analysis of methylenetetrahydrofolate reductase family of proteins.
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MTHFR 677 (C-->T) polymorphism is not relevant for prognosis or therapy-associated toxicity in pediatric NHL: results from 484 patients of multicenter trial NHL-BFM 95.
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MTHFR and MTRR genotype and haplotype analysis and colorectal cancer susceptibility in a case-control study from the Czech Republic.
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MTHFR C677T and A1298C polymorphisms and cervical carcinoma susceptibility: meta-analyses based on 4421 individuals.
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MTHFR C677T and A1298C Polymorphisms in Breast Cancer, Gliomas and Gastric Cancer: A Review.
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MTHFR C677T and A1298C variant genotypes and the risk of microsatellite instability among Iranian colorectal cancer patients.
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MTHFR C677T polymorphism and anatomopathological characteristics with prognostic significance in sporadic colorectal cancer.
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MTHFR C677T polymorphism and differential methylation status in gastric cancer: an association with Helicobacter pylori infection.
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MTHFR C677T polymorphism interaction with heavy alcohol consumption increases head and neck carcinoma risk.
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MTHFR C677T Polymorphism is Associated with Tumor Response to Preoperative Chemoradiotherapy: A Result Based on Previous Reports.
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MTHFR C677T polymorphism: association with lymphoid neoplasm and effect on methotrexate therapy.
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MTHFR Gene Polymorphisms and Bladder Cancer Susceptibility: a Meta-Analysis Including Race, Smoking Status and Tumour Stage.
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MTHFR Gene variants C677T, A1298C and association with Down syndrome: A Case-control study from South India.
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MTHFR Knockdown Assists Cell Defense against Folate Depletion Induced Chromosome Segregation and Uracil Misincorporation in DNA.
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MTHFR polymorphism and the risk of prostate cancer: a meta-analysis of case-control studies.
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MTHFR polymorphysms in myelodysplastic syndromes and therapy-related myeloid neoplasms.
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MTHFR single nucleotide polymorphism associated with working memory in pediatric medulloblastoma survivors.
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MTHFR variants reduce the risk of G:C->A:T transition mutations within the p53 tumor suppressor gene in colon tumors.
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MTHFR/p53 polymorphisms as genetic factors for cervical intraepithelial neoplasia and cervical cancer in HPV-infected Mexican women.
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Multiple transcription start sites and alternative splicing in the methylenetetrahydrofolate reductase gene result in two enzyme isoforms.
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Multiplex PCR for simultaneous detection of 677 C-->T and 1298 A-->C polymorphisms in methylenetetrahydrofolate reductase gene for population studies of cancer risk.
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Murine diet/tissue and human brain tumorigenesis alter Mthfr/MTHFR 5'-end methylation.
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Mutational analysis of the MTHFR gene in breast cancer patients of Pakistani population.
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NAD-dependent methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase from ascites tumor cells. Purification and properties.
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No evidence of association of methylenetetrahydrofolate reductase polymorphism with occurrence of second neoplasms after treatment of childhood leukemia.
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Novel insights into the development of portal vein thrombosis in cirrhosis patients.
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One-carbon genetic variants and the role of MTHFD1 1958G>A in liver and colon cancer risk according to global DNA methylation.
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Pancreaticobiliary cancers with deficient methylenetetrahydrofolate reductase genotypes.
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Personalized Nutrition-Genes, Diet, and Related Interactive Parameters as Predictors of Cancer in Multiethnic Colorectal Cancer Families.
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Pharmacogenetic Predictors of Outcome in Patients with Stage II and III Colon Cancer Treated with Oxaliplatin and Fluoropyrimidine-Based Adjuvant Chemotherapy.
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Plasma B-vitamins and one-carbon metabolites and the risk of breast cancer in younger women.
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Polymorphic methyl group metabolism genes in patients with transitional cell carcinoma of the urinary bladder.
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Polymorphisms in Genes Involved in Folate Metabolism Modify the Association of Dietary and Circulating Folate and Vitamin B-6 with Cervical Neoplasia.
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Polymorphisms in methylenetetrahydrofolate reductase and cystathionine beta-synthase in oral cancer - a case-control study in southeastern Brazilians.
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Polymorphisms in MTHFR, MTR, RFC1 and CßS genes involved in folate metabolism and thyroid cancer: a case-control study.
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Polymorphisms in the methylenetetrahydrofolate reductase gene and prostate cancer risk.
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Polymorphisms in the MTHFR gene are associated with recurrence risk in lymph node-positive breast cancer patients.
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Polymorphisms in thymidylate synthase and methylenetetrahydrofolate reductase genes and the susceptibility to esophageal and stomach cancer with smoking.
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Polymorphisms of 5,10-methylenetetralydrofolate reductase (MTHFR), fruit and vegetable intake, and the risk of stomach cancer.
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Polymorphisms of Folate Pathway Enzymes (Methylenetetrahydrofolate Reductase and Thymidylate Synthase) and Their Relationship with Thymidylate Synthase Expression in Human Astrocytic Tumors.
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Polymorphisms of methylenetetrahydrofolate reductase (MTHFR) and susceptibility to pediatric acute lymphoblastic leukemia in a German study population.
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Polymorphisms of methylenetetrahydrofolate reductase and the risk of prostate cancer: a nested case-control study.
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Polymorphisms of MTHFR and susceptibility to oesophageal adenocarcinoma in a Caucasian United Kingdom population.
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Polymorphisms of MTHFR Associated with Higher Relapse/Death Ratio and Delayed Weekly MTX Administration in Pediatric Lymphoid Malignancies.
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Preliminary assessment of differential expression of candidate genes associated with atherosclerosis.
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Presence of the methylenetetrahydrofolate reductase gene polymorphism MTHFR C677T in molar tissue but not maternal blood predicts failure of methotrexate treatment for low-risk gestational trophoblastic neoplasia.
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Prevalence of factor V Leiden, FII G20210A, FXIII Val34Leu and MTHFR C677T polymorphisms in cancer patients with and without venous thrombosis.
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Prevalence of thrombophilic genetic factors among patients with retinitis pigmentosa.
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Preventive medical services not covered by public health insurance at Daiko Medical Center in Japan, 2004-2011.
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Protective association of MTHFR polymorphism on cervical intraepithelial neoplasia is modified by riboflavin status.
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Quantitative analysis of associations between DNA hypermethylation, hypomethylation, and DNMT RNA levels in ovarian tumors.
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Quantitative analysis of DNA methylation profiles in lung cancer identifies aberrant DNA methylation of specific genes and its association with gender and cancer risk factors.
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Quantitative proteomics reveals differentially expressed proteins in murine preneoplastic intestine in a model of intestinal tumorigenesis induced by low dietary folate and MTHFR deficiency.
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Regulation of Folate-Mediated One-Carbon Metabolism by Glycine N-Methyltransferase (GNMT) and Methylenetetrahydrofolate Reductase (MTHFR).
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Relationship between methylenetetrahydrofolate reductase C677T and A1298C genotypes and haplotypes and prostate cancer risk and aggressiveness.
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Relationship between MTHFR Gene Polymorphisms and Gastrointestinal Tumors Development: Perspective from Eastern Part of Turkey.
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Relevance of MTHFR polymorphisms with response to fluoropyrimidine-based chemotherapy in oesophagogastric cancer: a meta-analysis.
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Risk association of meningiomas with MTHFR C677T and GSTs polymorphisms: a meta-analysis.
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Risk factors for colon cancer in Northeastern Thailand: interaction of MTHFR codon 677 and 1298 genotypes with environmental factors.
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Risk factors for rectal cancer and methylenetetrahydrofolate reductase polymorphisms in a population in Northeast Thailand.
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Risk of colorectal cancer associated with the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism in the Kashmiri population.
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Role of MTHFR (677, 1298) haplotype in the risk of developing secondary leukemia after treatment of breast cancer and hematological malignancies.
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Role of MTHFR polymorphisms and folate levels in different phenotypes of sporadic colorectal cancers.
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Search for low penetrance alleles for colorectal cancer through a scan of 1467 non-synonymous SNPs in 2575 cases and 2707 controls with validation by kin-cohort analysis of 14 704 first-degree relatives.
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Severe encephalopathy induced by the first but not the second course of high-dose methotrexate mirrored by plasma homocysteine elevations and preceded by extreme differences in pretreatment plasma folate.
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Statistical Correlations of the Spontaneous Abortion with Trombophilia and Other Associated Pathologies.
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Study on Relationships of Tumor Status and Gene Polymorphism With Blood Concentration of MTX and Toxicities in 63 Pediatric Mature B Cell Lymphoma in Chinese Population.
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The 19-bp deletion of dihydrofolate reductase (DHFR), methylenetetrahydrofolate reductase (MTHFR) C677T, Factor V Leiden, prothrombin G20210A polymorphisms in cancer patients with and without thrombosis.
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The activities of the NAD-dependent methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase from ascites tumor cells are kinetically independent.
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The association between methylenetetrahydrofolate reductase polymorphism and promoter methylation in proximal colon cancer.
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The association between MTHFR 677C>T genotype and folate status and genomic and gene-specific DNA methylation in the colon of individuals without colorectal neoplasia.
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The association between MTHFR C677T polymorphism and ovarian cancer risk: a meta-analysis of 18, 628 individuals.
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The association between the C677T polymorphism in MTHFR gene and the risk of thyroid cancer: a meta-analysis.
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The association of gastric cancer risk with plasma folate, cobalamin, and methylenetetrahydrofolate reductase polymorphisms in the European Prospective Investigation into Cancer and Nutrition.
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The Association of Protease Activated Receptor 1 gene -506 I/D Polymorphism with Disease-Free Survival in Breast Cancer Patients.
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The combination of methylenehydrofolate reductase C677T polymorphism screening and gastrointestinal tumor markers detection may be an early screening method for gastrointestinal cancer related to helicobacter pylori infection.
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The common 677C>T gene polymorphism of methylenetetrahydrofolate reductase gene is not associated with breast cancer risk.
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The effect of folate-related SNPs on clinicopathological features, response to neoadjuvant treatment and survival in pre- and postmenopausal breast cancer patients.
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The effect of methylenetetrahydrofolate reductase polymorphism C677T on cervical cancer in Korean women.
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The effects of polymorphisms in methylenetetrahydrofolate reductase (MTHFR), methionine synthase (MTR), and methionine synthase reductase (MTRR) on the risk of cervical intraepithelial neoplasia and cervical cancer in Korean women.
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The expression of mitochondrial methylenetetrahydrofolate dehydrogenase-cyclohydrolase supports a role in rapid cell growth.
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The folate pool in colorectal cancers is associated with DNA hypermethylation and with a polymorphism in methylenetetrahydrofolate reductase.
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The human and mouse methylenetetrahydrofolate reductase (MTHFR) genes: genomic organization, mRNA structure and linkage to the CLCN6 gene.
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The IL6 gene polymorphism -634C>G and IL17F gene polymorphism 7488T>C influence bone mineral density in young and elderly Japanese women.
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The Impact of MTHFR 1298 A?>?C and 677 C?>?T Gene Polymorphisms as Susceptibility Risk Factors in Cervical Intraepithelial Neoplasia Related to HPV and Sexually Transmitted Infections.
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The methionine synthase polymorphism c.2756A>G alters susceptibility to glioblastoma multiforme.
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The methylenetetrahydrofolate reductase (MTHFR) 677 C>T polymorphism increases the risk of developing chronic myeloid leukemia-a case-control study.
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The methylenetetrahydrofolate reductase (MTHFR) C677T gene polymorphism is associated with breast cancer subtype susceptibility in southwestern China.
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The methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and cancer risk: the Croatian case-control study.
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The methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and tumor risk: evidence from 134 case-control studies.
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The methylenetetrahydrofolate reductase (MTHFR) gene in colorectal cancer: role in tumor development and significance of allelic loss in tumor progression.
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The methylenetetrahydrofolate reductase 677C-->T polymorphism and lung cancer risk in a Chinese population.
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The methylenetetrahydrofolate reductase 677T-1298C haplotype is a risk factor for acute lymphoblastic leukemia in children.
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The methylenetetrahydrofolate reductase C677T mutation induces cell-specific changes in genomic DNA methylation and uracil misincorporation: a possible molecular basis for the site-specific cancer risk modification.
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The MTHFR 677C-->T polymorphism and risk of prostate cancer: results from the CAPS study.
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The MTHFR C677T and DeltaDNMT3B C-149T polymorphisms confer different risks for right- and left-sided colorectal cancer.
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The NADP-dependent trifunctional methylenetetrahydrofolate dehydrogenase purified from mouse liver is immunologically distinct from the mouse NAD-dependent [corrected] bifunctional enzyme.
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The protective effect of methylenetetrahydrofolate reductase C677T polymorphism against prostate cancer risk: Evidence from 23 case-control studies.
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The protective effects of the methylenetetrahydrofolate reductase rs1801131 variant among Saudi smokers.
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The role of MTHFR and RFC1 polymorphisms on toxicity and outcome of adult patients with hematological malignancies treated with high-dose methotrexate followed by leucovorin rescue.
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The role of the MTHFR 677C>T polymorphism in methotrexate-induced liver toxicity: a meta-analysis in patients with cancer.
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Thymidylate synthase and methylenetetrahy-drofolate reductase gene polymorphisms and gastric cancer susceptibility in a population of Northern Brazil.
Neoplasms
Thymidylate synthase and methylenetetrahydrofolate reductase gene polymorphisms: relationships with 5-fluorouracil sensitivity.
Neoplasms
TYMS, MTHFR, p53 and MDR1 gene polymorphisms in breast cancer patients treated with adjuvant therapy.
Neoplasms
Women with polymorphisms of methylenetetrahydrofolate reductase (MTHFR) and methionine synthase (MS) are less likely to have cervical intraepithelial neoplasia (CIN) 2 or 3.
Neoplasms
[Association between genetic polymorphisms in methylenetetrahydrofolate reductase and risk of breast cancer]
Neoplasms
[Association between genetic variations in methylenetetrahydrofolate reductase and risk of colorectal cancer in a Chinese population]
Neoplasms
[Clinical significance of thymidylate synthase and methylenetetrahydrofolate reductase gene polymorphism in Korean patients with gastric cancer]
Neoplasms
[Justifying genetic and immune markers of efficiency and sensitivity under combined exposure to risk factors in mining industry workers].
Neoplasms
[Polymorphic variants of folate metabolizing genes (C677T and A1298C MTHFR, C1420T SHMT1 and G1958A MTHFD) are not associated with the risk of breast cancer in West Siberian Region of Russia].
Neoplasms
[Prediction of response to neoadjuvant chemotherapy in Barrett's carcinoma by quantitative gene expression analysis]
Neoplasms
[Promoters of genes MTHFR from patients with hyperhomocysteinemia and PTEN from patients with malignant and benign endometrial and ovarian tumors]
Neoplasms
[Single nucleotide polymorphisms in methylenetetrahydrofolate reductase gene and susceptibility to cancer of the gastric cardia in Chinese population]
Neoplasms
[The relationship between methylenetetrahydrofolate reductase gene polymorphism and microsatellite instability in gastric cancer]
Neoplasms, Second Primary
No evidence of association of methylenetetrahydrofolate reductase polymorphism with occurrence of second neoplasms after treatment of childhood leukemia.
Neoplasms, Squamous Cell
Influence of MTHFR Genetic Background on p16 and MGMT Methylation in Oral Squamous Cell Cancer.
Nephritis
[Prognostic value of allelic variants affecting the hemostatic system in the development of antiphospholipid syndrome and kidney lesion in patients with systemic lupus erythematosus].
Nephrosclerosis
Methylenetetrahydrofolate reductase (MTHFR) polymorphism A1298C (Glu429Ala) predicts decline in renal function over time in the African-American Study of Kidney Disease and Hypertension (AASK) Trial and Veterans Affairs Hypertension Cohort (VAHC).
Nephrosclerosis
The MTHFR 677TT and 677CT/1298AC genotypes in Cypriot patients may be predisposing to hypertensive nephrosclerosis and chronic renal failure.
Nephrotic Syndrome
Arterial thrombosis associated with factor V Leiden and methylenetetrahydrofolate reductase C677T mutation in childhood membranous glomerulonephritis.
Nephrotic Syndrome
Cerebral sinovenous thrombosis associated with factor V Leiden and methylenetetrahydrofolate reductase A1298C mutation in adult membranous glomerulonephritis.
Nephrotic Syndrome
Methylenetetrahydrofolate reductase gene polymorphisms in patients with nephrotic syndrome.
Nervous System Diseases
Association between MTHFR Gene Polymorphisms and the Risk of Autism Spectrum Disorders: A Meta-Analysis.
Nervous System Diseases
Methylenetetrahydrofolate Reductase A1298C Polymorphism and Breast Cancer Risk: A Meta-analysis of 33 Studies.
Nervous System Diseases
Microarray analysis of brain RNA in mice with methylenetetrahydrofolate reductase deficiency and hyperhomocysteinemia.
Nervous System Diseases
The effects of diet, genetics and chemicals on toxicity and aberrant DNA methylation: an introduction.
Neural Tube Defects
"Polymorphisms in folate metabolism genes as maternal risk factor for neural tube defects: an updated meta-analysis"
Neural Tube Defects
5,10 Methylenetetrahydrofolate reductase genetic polymorphism as a risk factor for neural tube defects.
Neural Tube Defects
677-->CT mutation on the methylenetetrahydrofolate reductase gene is not a risk factor for neural tube defects in Turkey.
Neural Tube Defects
A genetic defect in 5,10 methylenetetrahydrofolate reductase in neural tube defects.
Neural Tube Defects
A1298C polymorphism of the MTHFR gene and neural tube defects in the state of Yucatan, Mexico.
Neural Tube Defects
Abnormal folate metabolism and genetic polymorphism of the folate pathway in a child with Down syndrome and neural tube defect.
Neural Tube Defects
Adaptive developmental plasticity in methylene tetrahydrofolate reductase (MTHFR) C677T polymorphism limits its frequency in South Indians.
Neural Tube Defects
Amniotic fluid homocysteine levels, 5,10-methylenetetrahydrafolate reductase genotypes, and neural tube closure sites.
Neural Tube Defects
Analysis of MTHFR 1298A>C in addition to MTHFR 677C>T polymorphism as a risk factor for neural tube defects in the Turkish population.
Neural Tube Defects
Analysis of the MTHFR 1298A-->C and 677C-->T polymorphisms as risk factors for neural tube defects.
Neural Tube Defects
Assessing the association between the methylenetetrahydrofolate reductase (MTHFR) 677C>T polymorphism and blood folate concentrations: a systematic review and meta-analysis of trials and observational studies.
Neural Tube Defects
Association between Fetal MTHFR A1298C (rs1801131) Polymorphism and Neural Tube Defects Risk: A Systematic Review and Meta-Analysis.
Neural Tube Defects
Association between MTHFR A1298C polymorphism and neural tube defect susceptibility: a metaanalysis.
Neural Tube Defects
Association between MTHFR C677T polymorphism and neural tube defect risks: A comprehensive evaluation in three groups of NTD patients, mothers, and fathers.
Neural Tube Defects
Association of congenital cardiac defects and the C677T methylenetetrahydrofolate reductase polymorphism.
Neural Tube Defects
Association of Fetal MTHFR C677T Polymorphism with Susceptibility to Neural Tube Defects: A Systematic Review and Update Meta-Analysis.
Neural Tube Defects
Association of FOLH1, DHFR, and MTHFR gene polymorphisms with susceptibility of Neural Tube Defects: A case control study from Eastern India.
Neural Tube Defects
Association of methylenetetrahydrofolate reductase genetic polymorphisms with atlantoaxial dislocation.
Neural Tube Defects
Association of MTHFR C677T, MTHFR A1298C, and MTRR A66G Polymorphisms with Neural Tube Defects in Tunisian Parents.
Neural Tube Defects
Association of neural tube defects in children of mothers with MTHFR 677TT genotype and abnormal carbohydrate metabolism risk: a case-control study.
Neural Tube Defects
Association of the 677C-->T mutation on the methylenetetrahydrofolate reductase gene in Turkish patients with neural tube defects.
Neural Tube Defects
Association of the C677T methylenetetrahydrofolate reductase mutation and elevated homocysteine levels with congenital cardiac malformations.
Neural Tube Defects
Association of the maternal MTHFR C677T polymorphism with susceptibility to neural tube defects in offsprings: evidence from 25 case-control studies.
Neural Tube Defects
Associations between prenatal exposure to cadmium and lead with neural tube defect risks are modified by single-nucleotide polymorphisms of fetal MTHFR and SOD2: a case-control study.
Neural Tube Defects
Bladder exstrophy-epispadias complex and the role of methylenetetrahydrofolate reductase C677T polymorphism: A case control study.
Neural Tube Defects
Bringing clarity to the role of MTHFR variants in neural tube defect prevention.
Neural Tube Defects
C677T mutation in methylenetetrahydrofolate reductase gene and neural tube defects: should Japanese women undergo gene screening before pregnancy?
Neural Tube Defects
C677T mutation of the methylenetetrahydrofolate reductase gene among the Korean infants in Seoul city.
Neural Tube Defects
C677T polymorphism in methylenetetrahydrofolate reductase gene and psychoses.
Neural Tube Defects
C677T polymorphism of the methylenetetrahydrofolate reductase gene does not affect folic acid, vitamin B12, and homocysteine serum levels in Turkish children with neural tube defects.
Neural Tube Defects
Characterization of a pseudogene for murine methylenetetrahydrofolate reductase.
Neural Tube Defects
Correction to: Associations between prenatal exposure to cadmium and lead with neural tube defect risks are modified by single-nucleotide polymorphisms of fetal MTHFR and SOD2: a case-control study.
Neural Tube Defects
Determining the association between methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms and genomic DNA methylation level: A meta-analysis.
Neural Tube Defects
Drug and environmental factors associated with adverse pregnancy outcomes. Part III: Folic acid: pharmacology, therapeutic recommendations, and economics.
Neural Tube Defects
Easy detection of 5,10-methylenetetrahydrofolate reductase 1298A/C genotype by mutagenically separated PCR assay.
Neural Tube Defects
Effects of Periconceptional Multivitamin Supplementation on Folate and Homocysteine Levels Depending on Genetic Variants of Methyltetrahydrofolate Reductase in Infertile Japanese Women.
Neural Tube Defects
Epigenetic profiles in children with a neural tube defect; a case-control study in two populations.
Neural Tube Defects
Erratum to: Variants in maternal COMT and MTHFR genes and risk of neural tube defects in offspring.
Neural Tube Defects
Erythrocyte volume, folate levels, and the presence of methylenetetrahydrofolate reductase polymorphism.
Neural Tube Defects
Evaluation of maternal serum folate, vitamin B12, and homocysteine levels andfactor V Leiden, factor II g.20210G>A, and MTHFR variations in prenatallydiagnosed neural tube defects.
Neural Tube Defects
Folate supplementation, MTHFR gene polymorphism and neural tube defects: a community based case control study in North India.
Neural Tube Defects
Frequency of the thermolabile variant C677T in the MTHFR gene and lack of association with neural tube defects in the State of Yucatan, Mexico.
Neural Tube Defects
Functional characterization of human methylenetetrahydrofolate reductase in Saccharomyces cerevisiae.
Neural Tube Defects
Gene-gene interaction between the cystathionine beta-synthase 31 base pair variable number of tandem repeats and the methylenetetrahydrofolate reductase 677C > T polymorphism on homocysteine levels and risk for neural tube defects.
Neural Tube Defects
Genetic polymorphisms in methylenetetrahydrofolate reductase and methionine synthase, folate levels in red blood cells, and risk of neural tube defects.
Neural Tube Defects
High prevalence of the thermolabile methylenetetrahydrofolate reductase variant in Mexico: a country with a very high prevalence of neural tube defects.
Neural Tube Defects
Hyperhomocysteinemia in men with a reproductive history of fetal neural tube defects: Three case reports and literature review.
Neural Tube Defects
Imaging and genetic investigations of neural tube defect in a calf: case report and review of the literature.
Neural Tube Defects
Impact of methylenetetrahydrofolate reductase deficiency and low dietary folate on the development of neural tube defects in splotch mice.
Neural Tube Defects
Impact of the MTHFR C677T polymorphism on risk of neural tube defects: case-control study.
Neural Tube Defects
In human alleles specific variation of MTHFR C677T and A1298C associated "risk factor" for the development of ovarian cancer.
Neural Tube Defects
Infant C677T mutation in MTHFR, maternal periconceptional vitamin use, and cleft lip.
Neural Tube Defects
Infant methylenetetrahydrofolate reductase 677TT genotype is a risk factor for congenital heart disease.
Neural Tube Defects
Insights on the structural perturbations in human MTHFR Ala222Val mutant by protein modeling and molecular dynamics.
Neural Tube Defects
Lifestyle, metabolite, and genetic determinants of formate concentrations in a cross-sectional study in young, healthy adults.
Neural Tube Defects
Low maternal folate concentrations and maternal MTHFR C677T polymorphism are associated with an increased risk for neural tube defects in offspring: a case-control study among Pakistani case and control mothers.
Neural Tube Defects
Maternal one-carbon metabolism, MTHFR and TCN2 genotypes and neural tube defects in India.
Neural Tube Defects
Metabolic effects and the methylenetetrahydrofolate reductase (MTHFR) polymorphism associated with neural tube defects in southern Brazil.
Neural Tube Defects
Metabolic effects of C677T and A1298C mutations at the MTHFR gene in Brazilian children with neural tube defects.
Neural Tube Defects
Methylenetetrahydrofolate reductase (MTHFR) deficiency enhances resistance against cytomegalovirus infection.
Neural Tube Defects
Methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms resulting in suboptimal oocyte maturation: a discussion of folate status, neural tube defects, schizophrenia, and vasculopathy.
Neural Tube Defects
Methylenetetrahydrofolate reductase (MTHFR) polymorphisms and risk of molecularly defined subtypes of childhood acute leukemia.
Neural Tube Defects
Methylenetetrahydrofolate reductase gene polymorphisms and neural tube defects epidemiology in the Slovak population.
Neural Tube Defects
Methylenetetrahydrofolate reductase gene polymorphisms and the risk of anencephaly in Mexico.
Neural Tube Defects
Methylenetetrahydrofolate reductase mutations, a genetic cause for familial recurrent neural tube defects.
Neural Tube Defects
Methylenetetrahydrofolate reductase thermolabile variant and oral clefts.
Neural Tube Defects
Molecular phylogenetic analysis of methylenetetrahydrofolate reductase family of proteins.
Neural Tube Defects
MTHFR 677 TT genotype in a mother and her child with Down syndrome, atrioventricular canal and exstrophy of the bladder: implications of a mutual genetic risk factor?
Neural Tube Defects
MTHFR 677C-->T and 1298A-->C polymorphisms: evaluation of maternal genotypic risk and association with level of neural tube defect.
Neural Tube Defects
MTHFR 677C->T genotype is associated with folate and homocysteine concentrations in a large, population-based, double-blind trial of folic acid supplementation.
Neural Tube Defects
MTHFR C677T and A1298C variants in Mexican Mestizo infants with neural tube defects from Western Mexico.
Neural Tube Defects
MTHFR C677T polymorphism as a risk factor of neural tube defects in Malay: a case control study.
Neural Tube Defects
Multiple transcription start sites and alternative splicing in the methylenetetrahydrofolate reductase gene result in two enzyme isoforms.
Neural Tube Defects
Mutational landscape screening of methylene tetrahydrofolate reductase to predict homocystinuria associated variants: An integrative computational approach.
Neural Tube Defects
Neonatal and fetal methylenetetrahydrofolate reductase genetic polymorphisms: an examination of C677T and A1298C mutations.
Neural Tube Defects
Neural tube defects, methylenetetrahydrofolate reductase mutation, and north/south dietary differences in China.
Neural Tube Defects
Polymorphisms in the methylenetetrahydrofolate reductase gene: clinical consequences.
Neural Tube Defects
Polymorphisms of methylenetetrahydrofolate reductase (MTHFR) and susceptibility to pediatric acute lymphoblastic leukemia in a German study population.
Neural Tube Defects
Possible interaction of genotypes at cystathionine beta-synthase and methylenetetrahydrofolate reductase (MTHFR) in neural tube defects. NTD Collaborative Group.
Neural Tube Defects
Presence of the 5,10-methylenetetrahydrofolate reductase C677T mutation in Puerto Rican patients with neural tube defects.
Neural Tube Defects
Retrospective approach to methylenetetrahydrofolate reductase mutations in children.
Neural Tube Defects
Role of amniotic fluid homocysteine level and of fetal 5, 10-methylenetetrahydrafolate reductase genotype in the etiology of neural tube defects.
Neural Tube Defects
Role of parental folate pathway single nucleotide polymorphisms in altering the susceptibility to neural tube defects in South India.
Neural Tube Defects
Screening of the C677T mutation on the methylenetetrahydrofolate reductase gene in French patients with neural tube defects.
Neural Tube Defects
Semiautomated DNA mutation analysis using a robotic workstation and molecular beacons.
Neural Tube Defects
Sequential multiple retinal vein occlusions and transient ischemic attack in MTHFR polymorphism and protein S deficiency.
Neural Tube Defects
Severe and mild mutations in cis for the methylenetetrahydrofolate reductase (MTHFR) gene, and description of five novel mutations in MTHFR.
Neural Tube Defects
Study of MTHFR and MS polymorphisms as risk factors for NTD in the Italian population.
Neural Tube Defects
Targeted insertion of two Mthfr promoters in mice reveals temporal- and tissue-specific regulation.
Neural Tube Defects
The "thermolabile" variant of methylenetetrahydrofolate reductase and neural tube defects: An evaluation of genetic risk and the relative importance of the genotypes of the embryo and the mother.
Neural Tube Defects
The association between maternal methylenetetrahydrofolate reductase C677T and A1298C polymorphism and birth defects and adverse pregnancy outcomes.
Neural Tube Defects
The C677T mutation in the methylenetetrahydrofolate reductase gene among the Indonesian Javanese population.
Neural Tube Defects
The curly-tail (ct) mouse, an animal model of neural tube defects, displays altered homocysteine metabolism without folate responsiveness or a defect in Mthfr.
Neural Tube Defects
The influence of 5,10 methylenetetrahydrofolate reductase genotypes on enzyme activity in placental tissue.
Neural Tube Defects
The methylenetetrahydrofolate reductase gene variant (C677T) as a susceptibility gene for tetralogy of Fallot.
Neural Tube Defects
The relation between erythrocyte volume and folate levels is influenced by a common mutation in the methylenetetrahydrofolate reductase (MTHFR) gene (C677T).
Neural Tube Defects
The thermolabile variant 677C-->T can further reduce activity when expressed in cis with severe mutations for human methylenetetrahydrofolate reductase.
Neural Tube Defects
The thermolabile variant of methylenetetrahydrofolate reductase (MTHFR) is not a major risk factor for neural tube defect in American Caucasians. The NTD Collaborative Group.
Neural Tube Defects
Transcobalamin and methionine synthase reductase mutated polymorphisms aggravate the risk of neural tube defects in humans.
Neural Tube Defects
Unique holoenzyme dimers of the tetrameric enzyme Escherichia coli methylenetetrahydrofolate reductase: characterization of structural features associated with modulation of the enzyme's function.
Neural Tube Defects
Updated investigations of the role of methylenetetrahydrofolate reductase in human neural tube defects.
Neural Tube Defects
Variants in maternal COMT and MTHFR genes and risk of neural tube defects in offspring.
Neural Tube Defects
Variants in MTHFR gene and neural tube defects susceptibility in China.
Neural Tube Defects
[C677T and A1298C MTHFR polymorphisms in the etiology of neural tube defects in Spanish population]
Neural Tube Defects
[Geographical distribution characteristics of one carbon metabolic pathway related single nucleotide polymorphisms].
Neural Tube Defects
[Meta-analysis on relationship between the Chinese maternal MTHFR gene polymorphism(C677T) and neural tube defects in offspring].
Neural Tube Defects
[Mutations of MTHFR, MTR, MTRR genes as high risk factors for neural tube defects]
Neural Tube Defects
[Polymorphism of the methylenetetrahydrofolate reductase gene (MTHFR) and incidence of hyperhomocysteinemia-related diseases]
Neural Tube Defects
[The common C677T polymorphism in the methylenetetrahydrofolate reductase gene is associated with neural tube defects and preeclampsia]
Neural Tube Defects
[The significance of folate metabolism in complications of pregnant women].
Neuroblastoma
Antisense inhibition of methylenetetrahydrofolate reductase reduces cancer cell survival in vitro and tumor growth in vivo.
Neuroblastoma
MTHFR and VDR Polymorphisms Improve the Prognostic Value of MYCN Status on Overall Survival in Neuroblastoma Patients.
Neuroblastoma
Reduced folate carrier-1 G80a gene polymorphism is associated with neuroblastoma's development.
Neuroblastoma
RFC-1 80G>A Polymorphism in Case-Mother/Control-Mother Dyads Is Associated with Risk of Nephroblastoma and Neuroblastoma.
Neurodegenerative Diseases
Association of the C677T and A1298C polymorphisms of methylenetetrahydrofolate reductase gene in patients with essential tremor in Turkey.
Neurodegenerative Diseases
Association of the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism with primary glaucoma in Saudi population.
Neurodegenerative Diseases
Genetic variation in the methylenetetrahydrofolate reductase gene, MTHFR, does not alter the risk of visual failure in Leber's hereditary optic neuropathy.
Neurodegenerative Diseases
Genetics and Epigenetics of One-Carbon Metabolism Pathway in Autism Spectrum Disorder: A Sex-Specific Brain Epigenome?
Neurodegenerative Diseases
Mthfr as a modifier of the retinal phenotype of Crb1(rd8/rd8) mice.
Neurofibroma
Are the methylenetetrahydrofolate reductase 1298 and 677 gene polymorphisms related to optic glioma and hamartoma risk in neurofibromatosis type 1 patients?
Neurofibromatoses
Are the methylenetetrahydrofolate reductase 1298 and 677 gene polymorphisms related to optic glioma and hamartoma risk in neurofibromatosis type 1 patients?
Neurofibromatoses
Coexistence of Neurofibromatosis Type-1 and MTHFR C677T Gene Mutation in a Young Stroke Patient: A Case Report.
Neurofibromatosis 1
Are the methylenetetrahydrofolate reductase 1298 and 677 gene polymorphisms related to optic glioma and hamartoma risk in neurofibromatosis type 1 patients?
Neurologic Manifestations
A newborn case with perinatal-lethal Gaucher disease due to R463H homozygosity complicated by C677T homozygosity in the MTHFR gene.
Neurologic Manifestations
Methylenetetrahydrofolate reductase (MTHFR) deficiency and infantile epilepsy.
Neuronal Ceroid-Lipofuscinoses
Inborn Errors of Metabolism Associated With Autism Spectrum Disorders: Approaches to Intervention.
Neurotoxicity Syndromes
Toxic encephalopathy and delayed MTX clearance after high-dose methotrexate therapy in a child homozygous for the MTHFR C677T polymorphism.
Neutropenia
Association of C677T and A1298C MTHFR Polymorphisms and Fluoropyrimidine-induced Toxicity in Mestizo Patients With Metastatic Colorectal Cancer.
Neutropenia
Correlation Between Methylenetetrahydrofolate Reductase (MTHFR) C677T Polymorphisms and Pemetrexed Chemotherapy Efficacy/Toxicity in Non-Squamous Non-Small Cell Lung Cancer.
Neutropenia
DPYD*2A and MTHFR C677T predict toxicity and efficacy, respectively, in patients on chemotherapy with 5-fluorouracil for colorectal cancer.
Neutropenia
Folate pathway genetic polymorphisms modulate methotrexate-induced toxicity in childhood acute lymphoblastic leukemia.
Neutropenia
Gene-Gene Interactions of Gemcitabine Metabolizing-Enzyme Genes hCNT3 and WEE1 for Preventing Severe Gemcitabine-Induced Hematological Toxicity.
Neutropenia
Influence of chemotherapeutic drug-related gene polymorphisms on toxicity and survival of early breast cancer patients receiving adjuvant chemotherapy.
Neutropenia
Pharmacogenetic studies in children with acute lymphoblastic leukemia in Argentina.
Neutropenia
Study on Relationships of Tumor Status and Gene Polymorphism With Blood Concentration of MTX and Toxicities in 63 Pediatric Mature B Cell Lymphoma in Chinese Population.
Niemann-Pick Diseases
Inborn Errors of Metabolism Associated With Autism Spectrum Disorders: Approaches to Intervention.
Non-alcoholic Fatty Liver Disease
Associations between Methylenetetrahydrofolate Reductase (MTHFR) Polymorphisms and Non-Alcoholic Fatty Liver Disease (NAFLD) Risk: A Meta-Analysis.
Non-alcoholic Fatty Liver Disease
Methylenetetrahydrofolate reductase C677T mutation and nonalcoholic fatty liver disease.
Non-alcoholic Fatty Liver Disease
Methylenetetrahydrofolate Reductase Gene Polymorphism and Serum Homocysteine Levels in Nonalcoholic Fatty Liver Disease.
Non-alcoholic Fatty Liver Disease
Methylenetetrahydrofolate reductase gene polymorphisms in patients with nonalcoholic steatohepatitis (NASH).
Non-alcoholic Fatty Liver Disease
MiR-149 Compromises the Reactions of Liver Cells to Fatty Acid via its Polymorphism and Increases Non-Alcoholic Fatty Liver Disease (NAFLD) Risk by Targeting Methylene Tetrahydrofolate Reductase (MTHFR).
Non-alcoholic Fatty Liver Disease
MTHFR 677C/T and 1298A/C mutations and non-alcoholic fatty liver disease.
Non-alcoholic Fatty Liver Disease
Non-alcoholic fatty liver disease (NAFLD) and MTHFR 1298A > C gene polymorphism.
Non-alcoholic Fatty Liver Disease
Plasmatic higher levels of homocysteine in non-alcoholic fatty liver disease (NAFLD).
Non-alcoholic Fatty Liver Disease
The methylenetetrahydrofolate reductase genotype 677CT and non-alcoholic fatty liver disease have a synergistic effect on the increasing homocysteine levels in subjects from Chongqing, China.
Non-alcoholic Fatty Liver Disease
[C677T AND A1298C ALLELE POLYMORPHISM GENE OF METHYLENETETRAHYDRAFOLATEREDUCTASE IN PATIENTS WITH NONALCOHOLIC FATTY LIVER DISEASE AND TYPE 2 DIABETES].
Obesity
A comparison of the genetic and clinical risk factors for arterial hypertension between indigenous and non-indigenous people of the Shoria Mountain Region.
Obesity
A systematic review of genetic variants associated with metabolic syndrome in patients with schizophrenia.
Obesity
Are genetic variants of the methyl group metabolism enzymes risk factors predisposing to obesity?
Obesity
Association of Methylene Tetrahydrofolate Reductase C677T Genotype With Type 2 Diabetes Mellitus Patients With and Without Renal Complications.
Obesity
Association of MTHFR genetic polymorphisms with venous thromboembolism in Uyghur population in Xinjiang, China.
Obesity
Association of the MTHFR 677C>T Polymorphism with Obesity and Biochemical Variables in a Young Population of Mexico.
Obesity
C677T gene polymorphism of MTHFR and metabolic syndrome: response to dietary intervention.
Obesity
Common polymorphisms in six genes of the methyl group metabolism pathway and obesity in European adolescents.
Obesity
Effect of maternal folic acid supplementation on hepatic one-carbon unit associated gene expressions in newborn piglets.
Obesity
Effect of MTHFR (rs1801133) and FTO (rs9939609) genetic polymorphisms and obesity in T2DM: a study among Bengalee Hindu caste population of West Bengal, India.
Obesity
Effects of a high-fat-sucrose diet on enzymes in homocysteine metabolism in the rat.
Obesity
Elite athletes¿ genetic predisposition for altered risk of complex metabolic traits.
Obesity
Gene-gene interactions and associations of six hypertension related single nucleotide polymorphisms with obesity risk in a Chinese children population.
Obesity
Influence of the C677T Polymorphism of the MTHFR Gene on Oxidative Stress in Women With Overweight or Obesity: Response to a Dietary Folate Intervention.
Obesity
Interrelation of cardiovascular risk factors with high albuminury among patients with arterial hypertension living in Mountain Shoriya.
Obesity
Low folate intake and serum levels are associated with higher body mass index and abdominal fat accumulation: a case control study.
Obesity
Methylene tetrahydrofolate reductase and angiotensin converting enzyme gene polymorphisms related to overweight/obesity among Saudi subjects from Qassim Region.
Obesity
Plausible relationship between homocysteine and obesity risk via MTHFR gene: a meta-analysis of 38,317 individuals implementing Mendelian randomization.
Obesity
Polymorphisms of the FTO and MTHFR genes and vascular, inflammatory and metabolic marker levels in postmenopausal women.
Obesity
Recurrent cerebral venous thrombosis associated with heterozygote methylenetetrahydrofolate reductase C677T mutation and sickle cell trait without homocysteinemia: an autopsy case report and review of literature.
Obesity
Single Nucleotide Polymorphisms in PEMT and MTHFR Genes are Associated with Omega 3 and 6 Fatty Acid Levels in the Red Blood Cells of Children with Obesity.
Obesity
The association of MTHFR C677T gene variants and lipid profiles or body mass index in patients with diabetic and nondiabetic coronary heart disease.
Obesity
The methylenetetrahydrofolate reductase C677T genotype and the risk of obesity in three large population-based cohorts.
Obesity
The MTHFR gene polymorphism is associated with lean body mass but not fat body mass.
Obesity
Variant alleles in factor V, prothrombin, plasminogen activator inhibitor-1, methylenetetrahydrofolate reductase and risk of thromboembolism in metastatic colorectal cancer patients treated with first-line chemotherapy plus bevacizumab.
Obesity
[Arterial Hypertension and Methylenetetrahydrofolate Reductase C677T Gene Polymorphism].
Obesity
[FETAL LOSSES DURING THE MATURATION OF THE PLACENTA AND THE RELATIONSHIP WITH SOME PROCOAGULANT CONDITIONS.]
Obesity
[Remodeling of the cardiovascular system and development of chronic kidney disease in patients with metabolic syndrome and obesity: role of eNOS, subunit p22-phox of NADPH-oxidase and MTHFR genes].
Obesity, Abdominal
Hyperhomocysteinemia and methylenetetrahydrofolate reductase polymorphism in a patient with coronary artery disease and repetitive miscarriages.
Obesity, Abdominal
Interrelation of cardiovascular risk factors with high albuminury among patients with arterial hypertension living in Mountain Shoriya.
Obesity, Morbid
Thrombosis Related ABO, F5, MTHFR, and FGG Gene Polymorphisms in Morbidly Obese Patients.
Obstetric Labor, Premature
Pulmonary embolism and premature labor in a patient with both factor V Leiden mutation and methylenetetrahydrofolate reductase gene C677T mutation.
Oligospermia
Association of the MTHFR A1298C variant with unexplained severe male infertility.
Oligospermia
Association study of four polymorphisms in three folate-related enzyme genes with non-obstructive male infertility.
Oligospermia
Correlation between methylenetetrahydrofolate reductase gene polymorphism and oligoasthenospermia and the effects of folic acid supplementation on semen quality.
Oligospermia
Effect of B9 and B12 vitamin intake on semen parameters and fertility of men with MTHFR polymorphisms.
Oligospermia
Effects of folic acid on oligozoospermia with MTHFR polymorphisms in term of seminal parameters, DNA fragmentation, and live birth rate: a double-blind, randomized, placebo-controlled trial.
Oligospermia
Influence of Methylenetetrahydrofolate Reductase C677T Gene Polymorphisms in Algerian Infertile Men with Azoospermia or Severe Oligozoospermia.
Oligospermia
Methylation Status of MTHFR Promoter and Oligozoospermia Risk: An Epigenetic Study and in Silico Analysis.
Oligospermia
Methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and male infertility risk: An updated meta-analysis.
Oligospermia
Methylenetetrahydrofolate reductase polymorphisms are related to male infertility in Brazilian men.
Oligospermia
Single nucleotide polymorphism C677T in the methylenetetrahydrofolate reductase gene might be a genetic risk factor for infertility for Chinese men with azoospermia or severe oligozoospermia.
Oligospermia
The relationship between methylenetetrahydrofolate reductase c.677TT genotype and oligozoospermia in infertile male patients living in the Trakya region of Turkey.
Opisthorchiasis
MTHFR Polymorphisms and Opisthorchis viverrini Infection: a Relationship with Increased Susceptibility to Cholangiocarcinoma in Thailand.
Optic Atrophy, Hereditary, Leber
Genetic variation in the methylenetetrahydrofolate reductase gene, MTHFR, does not alter the risk of visual failure in Leber's hereditary optic neuropathy.
Optic Nerve Diseases
Genetic variation in the methylenetetrahydrofolate reductase gene, MTHFR, does not alter the risk of visual failure in Leber's hereditary optic neuropathy.
Optic Nerve Diseases
Hyperhomocyst(e)inaemia, but not MTHFR C677T mutation, as a risk factor for non-arteritic ischaemic optic neuropathy.
Optic Nerve Glioma
Are the methylenetetrahydrofolate reductase 1298 and 677 gene polymorphisms related to optic glioma and hamartoma risk in neurofibromatosis type 1 patients?
Optic Neuropathy, Ischemic
Anterior ischemic optic neuropathy in a patient with Crohn's disease and aberrant MTHFR and GPIIIa gene variants.
Optic Neuropathy, Ischemic
Association Study of MTHFR Polymorphisms with Nonarteritic Anterior Ischemic Optic Neuropathy in a Spanish Population.
Optic Neuropathy, Ischemic
Hyperhomocyst(e)inaemia, but not MTHFR C677T mutation, as a risk factor for non-arteritic ischaemic optic neuropathy.
Optic Neuropathy, Ischemic
Nonarteritic anterior ischemic optic neuropathy: associations with homozygosity for the C677T methylenetetrahydrofolate reductase mutation.
Optic Neuropathy, Ischemic
Ocular vascular thrombotic events: a diagnostic window to familial thrombophilia (compound factor v leiden and prothrombin gene heterozygosity) and thrombosis.
Oral Ulcer
Association of MTHFR gene C677T mutation with recurrent aphthous stomatitis and number of oral ulcers.
ornithine aminotransferase deficiency
Targeted cerebrospinal fluid analysis for inborn errors of metabolism on an LC-MS/MS analysis platform.
Osteoarthritis
MTHFR gene C677T mutation and ACE gene I/D polymorphism in Turkish patients with osteoarthritis.
Osteonecrosis
A PAI-1 (SERPINE1) polymorphism predicts osteonecrosis in children with acute lymphoblastic leukemia: a report from the Children's Oncology Group.
Osteonecrosis
Association between MTHFR C677T polymorphism and osteonecrosis of the femoral head: a meta-analysis.
Osteonecrosis
Association of corticosteroids and factor V, prothrombin, and MTHFR gene mutations with avascular osteonecrosis in renal allograft recipients.
Osteonecrosis
Genetic Association between Methylenetetrahydrofolate Reductase Gene Polymorphism and Risk of Osteonecrosis of the Femoral Head.
Osteonecrosis
Genetic background of nontraumatic osteonecrosis of the femoral head in the korean population.
Osteonecrosis
Genetic risk factors for glucocorticoid-induced osteonecrosis: A meta-analysis.
Osteonecrosis
Lack of association of MTHFR gene polymorphisms with the risk of osteonecrosis of the femoral head in a Korean population.
Osteonecrosis
Methylenetetrahydrofolate reductase gene polymorphism and glucocorticoid intake in children with ALL and aseptic osteonecrosis.
Osteoporosis
A common methylenetetrahydrofolate reductase (C677T) polymorphism is associated with low bone mineral density and increased fracture incidence after menopause: longitudinal data from the Danish osteoporosis prevention study.
Osteoporosis
Are effects of MTHFR (C677T) genotype on BMD confined to women with low folate and riboflavin intake? Analysis of food records from the Danish osteoporosis prevention study.
Osteoporosis
Association of MTHFR C677T polymorphism with bone mineral density of osteoporosis in postmenopausal Thai women.
Osteoporosis
Association of plasma folate, plasma total homocysteine, but not methylenetetrahydrofolate reductase C667T polymorphism, with bone mineral density in postmenopausal Iranian women: a cross-sectional study.
Osteoporosis
Association of the methylenetetrahydrofolate reductase C677T polymorphism and fracture risk in Chinese postmenopausal women.
Osteoporosis
Effect of MTHFR, TGF?1, and TNFB polymorphisms on osteoporosis in rheumatoid arthritis patients.
Osteoporosis
Genome-wide association with bone mass and geometry in the Framingham Heart Study.
Osteoporosis
MTHFR C677T, MTHFR A1298C, and OPG A163G polymorphisms in Mexican patients with rheumatoid arthritis and osteoporosis.
Osteoporosis
Pregnancy-associated osteoporosis with a heterozygous deactivating LDL receptor-related protein 5 (LRP5) mutation and a homozygous methylenetetrahydrofolate reductase (MTHFR) polymorphism.
Osteoporosis
The effects of homocysteine and MTHFR genotype on hip bone loss and fracture risk in elderly women.
Osteoporosis
[Polymorphisms in xenobiotic-metabolizing genes in the pathogenesis of glucocorticoid-induced osteoporosis in patients with bronchial asthma].
Osteoporosis, Postmenopausal
Association of the MTHFR C677T polymorphism and bone mineral density in postmenopausal women: a meta-analysis.
Osteosarcoma
Association of MTHFR and ABCB1 polymorphisms with MTX-induced mucositis in Chinese paediatric patients with acute lymphoblastic leukaemia, lymphoma or osteosarcoma-A retrospective cohort study.
Osteosarcoma
ATIC Gene Polymorphism and Histologic Response to Chemotherapy in Pediatric Osteosarcoma.
Osteosarcoma
Impact of genetic variants of RFC1, DHFR and MTHFR in osteosarcoma patients treated with high-dose methotrexate.
Osteosarcoma
Methylenetetrahydrofolate reductase C677T gene polymorphism in osteosarcoma and chondrosarcoma patients.
Osteosarcoma
More severe toxicity of genetic polymorphisms on MTHFR activity in osteosarcoma patients treated with high-dose methotrexate.
Osteosarcoma
MTHFR variant is associated with high-dose methotrexate-induced toxicity in the Chinese osteosarcoma patients.
Osteosarcoma
Pharmacogenetics in cancer therapy - 8 years of experience at the Institute for Oncology and Radiology of Serbia.
Osteosarcoma
The role of the MTHFR C677T polymorphism in methotrexate-induced toxicity in pediatric osteosarcoma patients.
Ovarian Hyperstimulation Syndrome
A case of ovarian hyperstimulation syndrome associated with the methylenetetrahydrofolate reductase mutation gene.
Ovarian Neoplasms
Association between MTHFR Gene Polymorphism and the Risk of Ovarian Cancer: A Meta-analysis of the Literature.
Ovarian Neoplasms
Association of MTHFR 677C>T Polymorphism with Susceptibility to Ovarian and Cervical Cancers: A Systematic Review and Meta-Analysis.
Ovarian Neoplasms
ASSOCIATION OF MTHFR A1298C POLYMORPHISM WITH BREAST CANCER AND/OR OVARIAN CANCER RISK: AN UPDATED META-ANALYSIS.
Ovarian Neoplasms
Association of PHB 1630 C>T and MTHFR 677 C>T polymorphisms with breast and ovarian cancer risk in BRCA1/2 mutation carriers: results from a multicenter study.
Ovarian Neoplasms
Association of the C677T polymorphism in the MTHFR gene with breast and/or ovarian cancer risk in Jewish women.
Ovarian Neoplasms
Effect of methylenetetrahydrofolate reductase 677C-->T polymorphism on toxicity and homocysteine plasma level after chronic methotrexate treatment of ovarian cancer patients.
Ovarian Neoplasms
Effects of methylenetetrahydrofolate reductase single-nucleotide polymorphisms on breast, cervical, ovarian, and endometrial cancer susceptibilities.
Ovarian Neoplasms
Folate and choline metabolism gene variants in relation to ovarian cancer risk in the Polish population.
Ovarian Neoplasms
Folate intake and methylenetetrahydrofolate reductase gene polymorphisms as predictive and prognostic biomarkers for ovarian cancer risk.
Ovarian Neoplasms
Folate intake and MTHFR polymorphism C677T is not associated with ovarian cancer risk: evidence from the meta-analysis.
Ovarian Neoplasms
Genetic polymorphisms of methylenetetrahydrofolate reductase (MTHFR) gene Ala222Val and susceptibility to ovary cancer: a systematic review and meta-analysis.
Ovarian Neoplasms
Homocysteinemia is inversely correlated with platelet count and directly correlated with sE- and sP-selectin levels in females homozygous for C677T methylenetetrahydrofolate reductase.
Ovarian Neoplasms
In human alleles specific variation of MTHFR C677T and A1298C associated "risk factor" for the development of ovarian cancer.
Ovarian Neoplasms
Lack of Significance of the BRCA2 Promoter Methylation Status in Different Genotypes of the MTHFR a1298c Polymorphism in Ovarian Cancer Cases in Iran.
Ovarian Neoplasms
Methylenetetrahydrofolate reductase gene polymorphisms as predictive and prognostic biomarkers in ovarian cancer risk.
Ovarian Neoplasms
Methylenetetrahydrofolate reductase gene polymorphisms in the risk of polycystic ovary syndrome and ovarian cancer.
Ovarian Neoplasms
Methylenetetrahydrofolate reductase polymorphisms modify BRCA1-associated breast and ovarian cancer risks.
Ovarian Neoplasms
The association between MTHFR C677T polymorphism and ovarian cancer risk: a meta-analysis of 18, 628 individuals.
Ovarian Neoplasms
[No association between MTHFR 677C>T polymorphism and ovarian cancer risk in BRCA1 mutation carriers in Wielkopolska region].
Overweight
Association of the MTHFR 677C>T Polymorphism with Obesity and Biochemical Variables in a Young Population of Mexico.
Overweight
Food Intervention with Folate Reduces TNF-? and Interleukin Levels in Overweight and Obese Women with the MTHFR C677T Polymorphism: A Randomized Trial.
Overweight
Influence of the C677T Polymorphism of the MTHFR Gene on Oxidative Stress in Women With Overweight or Obesity: Response to a Dietary Folate Intervention.
Overweight
Lack of association between methylenetetrahydrofolate reductase (MTHFR) C677T and ischaemic heart disease (IHD): family-based association study in a Spanish population.
Overweight
Methylene tetrahydrofolate reductase and angiotensin converting enzyme gene polymorphisms related to overweight/obesity among Saudi subjects from Qassim Region.
Overweight
Methylenetetrahydrofolate reductase (MTHFR) polymorphism (C677T) in relation to homocysteine concentration in overweight and obese Thais.
Overweight
Personalized Nutrition-Genes, Diet, and Related Interactive Parameters as Predictors of Cancer in Multiethnic Colorectal Cancer Families.
Pancreatic Neoplasms
Alcohol drinking and one-carbon metabolism-related gene polymorphisms on pancreatic cancer risk.
Pancreatic Neoplasms
Association of MTHFR gene polymorphisms with pancreatic cancer: meta-analysis of 17 case-control studies.
Pancreatic Neoplasms
Associations between polymorphisms in folate-metabolizing genes and pancreatic cancer risk in Japanese subjects.
Pancreatic Neoplasms
Effect of MTHFR Polymorphisms on Gastrointestinal Cancer Risk in Italy.
Pancreatic Neoplasms
Folate intake, MTHFR polymorphisms, and risk of esophageal, gastric, and pancreatic cancer: a meta-analysis.
Pancreatic Neoplasms
Genetic polymorphisms in methylenetetrahydrofolate reductase and thymidylate synthase and risk of pancreatic cancer.
Pancreatic Neoplasms
MTHFR gene polymorphisms are not involved in pancreatic cancer risk: a meta-analysis.
Pancreatic Neoplasms
MTHFR Polymorphisms and Pancreatic Cancer Risk: Lack of Evidence from a Meta-analysis.
Pancreatic Neoplasms
Pancreaticobiliary cancers with deficient methylenetetrahydrofolate reductase genotypes.
Pancreatic Neoplasms
[Study on the relations between genetic polymorphisms in methylenetetrahydrofolate reductase, methionine synthase and the risk of pancreatic cancer]
Pancreatitis, Chronic
Association of 5, 10- methylenetetrahydrofolate reductase C677T polymorphism in susceptibility to tropical chronic pancreatitis in north Indian population.
Pancreatitis, Chronic
MTHFR C677T polymorphism in chronic pancreatitis and pancreatic adenocarcinoma.
Papilloma
Investigation of Methylenetetrahydrofolate Reductase C677T Polymorphism and Human Papilloma Virus Genotypes in Iranian Breast Cancer.
Papilloma
Protective association of MTHFR polymorphism on cervical intraepithelial neoplasia is modified by riboflavin status.
Papilloma
The effect of methylenetetrahydrofolate reductase polymorphisms on susceptibility to human papilloma virus infection and cervical cancer.
Papilloma
Women with polymorphisms of methylenetetrahydrofolate reductase (MTHFR) and methionine synthase (MS) are less likely to have cervical intraepithelial neoplasia (CIN) 2 or 3.
Papillomavirus Infections
Lack of association between methylenetetrahydrofolate reductase C677T polymorphism, HPV infection and cervical intraepithelial neoplasia in Brazilian women.
Papillomavirus Infections
Methylenetetrahydrofolate reductase (MTHFR) polymorphism increases the risk of cervical intraepithelial neoplasia.
Paralysis
5,10-Methylenetetrahydrofolate reductase deficiency with progressive polyneuropathy in an infant.
Paraparesis
Complete clinical and functional recovery following low-dose methotrexate related paraparesis in a patient with compound c.1298A>C AND c.677C>T MTHFR polymorphism: A case report.
Paraparesis, Spastic
Mutations in MTHFR and POLG impaired activity of the mitochondrial respiratory chain in 46-year-old twins with spastic paraparesis.
Paraparesis, Spastic
Recessive spastic paraparesis associated with complex I deficiency due to MTHFR mutations.
Paraparesis, Spastic
Severe methylenetetrahydrofolate reductase deficiency: clinical clues to a potentially treatable cause of adult-onset hereditary spastic paraplegia.
Paraplegia
Adult-onset severe methylenetetrahydrofolate reductase deficiency characterized by reversible spastic paraplegia with a novel mutation.
Paraplegia
Psychosis, paraplegia and coma revealing methylenetetrahydrofolate reductase deficiency in a 56-year-old woman.
Paresis
A case of portal vein thrombosis after laparoscopy-assisted splenectomy and cholecystectomy in a child.
Paresis
MTHFR homozygous mutation and additional risk factors for cerebral infarction in a large Italian family.
Parkinson Disease
5,10-methylenetetrahydrofolate reductase C677T gene polymorphism can influence age at onset of Parkinson's disease.
Parkinson Disease
Association Between MTHFR Genetic Polymorphism and Parkinson's Disease Susceptibility: A Meta-analysis.
Parkinson Disease
Association of COMT, MTHFR, and SLC19A1(RFC-1) polymorphisms with homocysteine blood levels and cognitive impairment in Parkinson's disease.
Parkinson Disease
Association of MTHFR C677T with total homocysteine plasma levels and susceptibility to Parkinson's disease: a meta-analysis.
Parkinson Disease
Association of MTHFR, MTR, and MTRR polymorphisms with Parkinson's disease among ethnic Chinese in Taiwan.
Parkinson Disease
Association of the MTHFR rs1801131 and rs1801133 variants in sporadic Parkinson's disease patients.
Parkinson Disease
Association of the rs1801133 variant in the MTHFR gene and sporadic Parkinson's disease.
Parkinson Disease
Coenzyme Q10, Hyperhomocysteinemia and MTHFR C677T Polymorphism in Levodopa-treated Parkinson's Disease Patients.
Parkinson Disease
Differences in MTHFR and LRRK2 variant's association with sporadic Parkinson's disease in Mexican Mestizos correlated to Native American ancestry.
Parkinson Disease
Genetic causes of Parkinson's disease in the Maltese: a study of selected mutations in LRRK2, MTHFR, QDPR and SPR.
Parkinson Disease
Homocysteine Level and Mechanisms of Injury in Parkinson's Disease as Related to MTHFR, MTR, and MTHFD1 Genes Polymorphisms and L-Dopa Treatment.
Parkinson Disease
Homocysteine serum levels and MTHFR C677T genotype in patients with Parkinson's disease, with and without levodopa therapy.
Parkinson Disease
Hyperhomocysteinemia and methylenetetrahydrofolate reductase polymorphism in patients with Parkinson's disease.
Parkinson Disease
Hypertrophy of IMC of carotid artery in Parkinson's disease is associated with L-DOPA, homocysteine, and MTHFR genotype.
Parkinson Disease
Meta-analysis supports association of a functional SNP (rs1801133) in the MTHFR gene with Parkinson's disease.
Parkinson Disease
Methylenetetrahydrofolate reductase (MTHFR) C677T/A1298C polymorphisms and susceptibility to Parkinson's disease: A meta-analysis.
Parkinson Disease
Methylenetetrahydrofolate reductase polymorphisms and plasma homocysteine in levodopa-treated and non-treated Parkinson's disease patients.
Parkinson Disease
MTHFR C677T and A1298C polymorphisms may contribute to the risk of Parkinson's disease: A meta-analysis of 19 studies.
Parkinson Disease
MTHFR C677T polymorphism, folic acid and hyperhomocysteinemia in levodopa treated patients with Parkinson's disease.
Parkinson Disease
MTHFR C677T variant reduces risk of sporadic Parkinson's disease in ethnic Chinese.
Parkinson Disease
The MTHFR C677T polymorphism modifies age at onset in Parkinson's disease.
Parkinsonian Disorders
A case of vascular parkinsonism associated with hyperhomocysteinemia and methylenetetrahydrofolate reductase gene variant (C677T).
Pediatric Obesity
Common polymorphisms in six genes of the methyl group metabolism pathway and obesity in European adolescents.
Periodontitis
miR-9-1 gene methylation and DNMT3B (rs2424913) polymorphism may contribute to periodontitis.
Peripheral Arterial Disease
5,10-methylenetetrahydrofolate reductase C677T gene polymorphism and peripheral arterial disease: A meta-analysis.
Peripheral Arterial Disease
A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase.
Peripheral Arterial Disease
Factor V Leiden, prothrombin G20210A, and methylenetetrahydrofolate reductase C677T mutations are not associated with chronic limb ischemia: the Linz Peripheral Arterial Disease (LIPAD) study.
Peripheral Arterial Disease
Hyperhomocysteinaemia is an independent risk factor of abdominal aortic aneurysm in a Chinese Han population.
Peripheral Arterial Disease
Methylene tetrahydrofolate reductase (MTHFR) and nitric oxide synthase (ecNOS) genes and risks of peripheral arterial disease and coronary heart disease: Edinburgh Artery Study.
Peripheral Arterial Disease
Methylenetetrahydrofolate reductase polymorphism 677C>T is associated with peripheral arterial disease in type 2 diabetes.
Peripheral Arterial Disease
Peripheral arterial disease and methylenetetrahydrofolate reductase (MTHFR) C677T mutations: A case-control study and meta-analysis.
Peripheral Nervous System Diseases
Association of MTHFR gene C677T mutation with diabetic peripheral neuropathy and diabetic retinopathy.
Peripheral Nervous System Diseases
Effect of betaine on S-adenosylmethionine levels in the cerebrospinal fluid in a patient with methylenetetrahydrofolate reductase deficiency and peripheral neuropathy.
Peripheral Nervous System Diseases
Effects of Common Polymorphisms in the MTHFR and ACE Genes on Diabetic Peripheral Neuropathy Progression: a Meta-Analysis.
Peripheral Nervous System Diseases
Insidious peripheral neuropathy occurring under treatment in infantile MTHFR deficiency.
Peripheral Nervous System Diseases
Is the C677T polymorphism in methylenetetrahydrofolate reductase gene or plasma homocysteine a risk factor for diabetic peripheral neuropathy in Chinese individuals?
Peripheral Nervous System Diseases
Role of treatment-modifying MTHFR677C>T and 1298A>C polymorphisms in metformin-treated Puerto Rican patients with type-2 diabetes mellitus and peripheral neuropathy.
Peripheral Vascular Diseases
Association between factor V Leiden, prothrombin G20210A, and methylenetetrahydrofolate reductase C677T mutations and events of the arterial circulatory system: a meta-analysis of published studies.
Peripheral Vascular Diseases
Methylenetetrahydrofolate reductase gene and coronary artery disease.
Peripheral Vascular Diseases
MTHFR C677T Polymorphism as a Risk Factor for Vascular Calcification in Chronic Hemodialysis Patients.
Peripheral Vascular Diseases
Peripheral Vascular Disease Susceptibility Based on Diabetes Mellitus and rs17367504 Polymorphism of the MTHFR Gene.
Phenylketonurias
Subacute onset leukodystrophy and visual-spatial disorders revealing phenylketonuria combined with homocysteinmia in adulthood: A case report.
Placenta Accreta
Severe toxic effects of low-dose methotrexate treatment for placenta accreta in a patient with methylenetetrahydrofolate reductase mutations.
Placenta Previa
Anesthesia for cesarean section in a patient with placenta previa and methylenetetrahydrofolate reductase deficiency.
plasmin deficiency
Protein C and protein S deficiencies are the most important risk factors associated with thrombosis in Chinese venous thrombophilic patients in Taiwan.
Pneumonia, Mycoplasma
Posterior cerebral artery occlusion after Mycoplasma pneumoniae infection associated with genetic defect of MTHFR C677T.
Polyarteritis Nodosa
Co-existence of renovascular hypertension, polyarteritis nodosa, antiphospholipid syndrome and methylenetetrahydrofolate reductase mutation.
Polycystic Ovary Syndrome
A meta-analysis on associations of FTO, MTHFR and TCF7L2 polymorphisms with polycystic ovary syndrome.
Polycystic Ovary Syndrome
Association between a single nucleotide polymorphism in MTHFR gene and polycystic ovary syndrome.
Polycystic Ovary Syndrome
Association of methylenetetrahydrofolate reductase C677T and A1298C polymorphisms with genetic susceptibility to polycystic ovary syndrome: A PRISMA-compliant meta-analysis.
Polycystic Ovary Syndrome
Association of methylenetetrahydrofolate reductase gene C677T polymorphism with polycystic ovary syndrome risk: a systematic review and meta-analysis update.
Polycystic Ovary Syndrome
Association of three missense mutations in the homocysteine-related MTHFR and MTRR gene with risk of polycystic ovary syndrome in Southern Chinese women.
Polycystic Ovary Syndrome
Can the genetic polymorphisms of the folate metabolism have an influence in the polycystic ovary syndrome?
Polycystic Ovary Syndrome
Genetic polymorphism of Methylenetetrahydrofolate reductase is associated with insulin resistance in Egyptian women with polycystic ovary syndrome.
Polycystic Ovary Syndrome
Homocysteine levels and C677T polymorphism of methylenetetrahydrofolate reductase in women with polycystic ovary syndrome.
Polycystic Ovary Syndrome
Is MTHFR 677 C>T Polymorphism Clinically Important in Polycystic Ovarian Syndrome (PCOS)? A Case-Control Study, Meta-Analysis and Trial Sequential Analysis.
Polycystic Ovary Syndrome
Methylenetetrahydrofolate reductase C677T gene polymorphism in turkish patients with polycystic ovary syndrome.
Polycystic Ovary Syndrome
Methylenetetrahydrofolate reductase C677T polymorphism and the risks of polycystic ovary syndrome: an updated meta-analysis of 14 studies.
Polycystic Ovary Syndrome
Methylenetetrahydrofolate reductase gene polymorphisms in the risk of polycystic ovary syndrome and ovarian cancer.
Polycystic Ovary Syndrome
MTHFR C 677T mutation and 4G/5G PAI-1 polymorphism in patient with polycystic ovarian syndrome.
Polycystic Ovary Syndrome
MTHFR C677T polymorphism is associated with hyperlipidemia in women with polycystic ovary syndrome.
Polycystic Ovary Syndrome
Note of clarification of data in the meta-analysis of methylenetetrahydrofolate reductase C677T polymorphisms in polycystic ovary syndrome.
Polycystic Ovary Syndrome
Plasminogen Activator Inhibitor 1 and Methylenetetrahydrofolate Reductase Gene mutations in Iranian Women with Polycystic Ovary Syndrome.
Polycystic Ovary Syndrome
Plasminogen activator inhibitor-1 4G/5G and the MTHFR 677C/T polymorphisms and susceptibility to polycystic ovary syndrome: a meta-analysis.
Polycystic Ovary Syndrome
Polycystic ovary syndrome and the single nucleotide polymorphisms of methylenetetrahydrofolate reductase: a pilot observational study.
Polycystic Ovary Syndrome
Prevalence of Methylenetetrahydrofolate Reductase C677T Polymorphism in women with Polycystic Ovary Syndrome in southeast of Iran.
Polycystic Ovary Syndrome
Role of methylenetetrahydrofolate reductase C677T and A1298C polymorphisms in polycystic ovary syndrome risk.
Polycystic Ovary Syndrome
Significant association between methylenetetrahydrofolate reductase gene C677T polymorphism with polycystic ovary syndrome risk: A meta-analysis update.
Polycystic Ovary Syndrome
Thyroid vein thrombosis in a young woman with methylenetetrahydrofolate reductase gene mutation receiving cyproterone acetate/ethinylestradiol treatment for polycystic ovary syndrome: a case report.
Polycystic Ovary Syndrome
Variant Alleles of the ESR1, PPARG, HMGA2, and MTHFR Genes Are Associated With Polycystic Ovary Syndrome Risk in a Chinese Population: A Case-Control Study.
Polycystic Ovary Syndrome
[Association of methylenetetrahydrofolate reductase gene polymorphisms with polycystic ovary syndrome].
Polycythemia
Venous thromboembolism associated with hyperhomocysteinemia, homozygosity for the methylenetetrahydrofolate reductase 677C>T gene variant, and secondary polycythemia.
Polycythemia Vera
The relationship between factor V Leiden, prothrombin G20210A, and MTHFR mutations and the first major thrombotic episode in polycythemia vera and essential thrombocythemia.
Polyneuropathies
5,10-Methylenetetrahydrofolate reductase deficiency with progressive polyneuropathy in an infant.
Porphyrias
Inborn Errors of Metabolism Associated With Autism Spectrum Disorders: Approaches to Intervention.
Pre-Eclampsia
5,10 methylenetetrahydrofolate reductase polymorphism in black South African women with pre-eclampsia.
Pre-Eclampsia
677 C-->T polymorphism of the methylenetetrahydrofolate reductase gene and preeclampsia.
Pre-Eclampsia
Absence of association between a common mutation in the methylenetetrahydrofolate reductase gene and preeclampsia in Japanese women.
Pre-Eclampsia
Analysis of polymorphisms and haplotypes in genes associated with vascular tone, hypertension and oxidative stress in Mexican-Mestizo women with severe preeclampsia.
Pre-Eclampsia
Association between plasminogen activator inhibitor 1 gene polymorphisms and preeclampsia.
Pre-Eclampsia
Association between the methylenetetrahydrofolate reductase C677T polymorphism and susceptibility to preeclampsia: the need for data clarification in a recent meta-analysis.
Pre-Eclampsia
Association of C677T polymorphism in the methylenetetrahydrofolate reductase gene with hypertension in pregnancy and pre-eclampsia: a meta-analysis.
Pre-Eclampsia
Association of gene polymorphisms of FV, FII, MTHFR, SERPINE1, CTLA4, IL10, and TNFalpha with pre-eclampsia in Chinese women.
Pre-Eclampsia
Association of methylenetetrahydrofolate reductase C677T and reduced-f carrier-1 G80A gene polymorphism with preeclampsia in Sudanese women.
Pre-Eclampsia
Association of methylenetetrahydrofolate reductase C677T polymorphism with the pre-eclampsia risk in Hakka pregnant women in Southern China.
Pre-Eclampsia
Association of MTHFR A1298C polymorphism (but not of MTHFR C677T) with elevated homocysteine levels and placental vasculopathies.
Pre-Eclampsia
Association of MTHFR C677T Polymorphism with Preeclampsia in North East of Iran (Khorasan Province).
Pre-Eclampsia
Association of pre-eclampsia with hyperhomocysteinaemia and methylenetetrahydrofolate reductase gene C677T polymorphism in a Turkish population.
Pre-Eclampsia
Candidate gene study of genetic thrombophilic polymorphisms in pre-eclampsia and recurrent pregnancy loss in Sinhalese women.
Pre-Eclampsia
Carriage of the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism does not influence the first and second trimester uterine artery Doppler flow.
Pre-Eclampsia
Correlation between MTHFR gene methylation and pre-eclampsia, and its clinical significance.
Pre-Eclampsia
Differential global and MTHFR gene specific methylation patterns in preeclampsia and recurrent miscarriages: A case-control study from North India.
Pre-Eclampsia
Epigenetic Modification in Methylene Tetrahydrofolate Reductase (MTHFR) Gene of Women with Pre-eclampsia.
Pre-Eclampsia
Epistasis between COMT and MTHFR in maternal-fetal dyads increases risk for preeclampsia.
Pre-Eclampsia
Ethnic differences in the association of factor V Leiden mutation and the C677T methylenetetrahydrofolate reductase gene polymorphism with preeclampsia.
Pre-Eclampsia
Evaluation of methylenetetrahydrofolate reductase (MTHFR) activity and the levels of homocysteine and malondialdehyde (MDA) in the serum of women with preeclampsia.
Pre-Eclampsia
Factor V Leiden and thermolabile methylenetetrahydrofolate reductase gene variants in an East Anglian preeclampsia cohort.
Pre-Eclampsia
Factor V Leiden, C > T MTHFR polymorphism and genetic susceptibility to preeclampsia.
Pre-Eclampsia
Factor V Leiden, Prothrombin and MTHFR Mutation in Patients with Preeclamsia, Intrauterine Growth Restriction and Placental Abruption.
Pre-Eclampsia
Fetal genotype for specific inherited thrombophilias is not associated with severe preeclampsia.
Pre-Eclampsia
Fetal Val108/158Met catechol-O-methyltransferase (COMT) polymorphism and placental COMT activity are associated with the development of preeclampsia.
Pre-Eclampsia
Folate metabolism gene polymorphisms MTHFR C677T and A1298C and risk for preeclampsia: a meta-analysis.
Pre-Eclampsia
Folic acid and homocyst(e)ine metabolic defects and the risk of placental abruption, pre-eclampsia and spontaneous pregnancy loss: A systematic review.
Pre-Eclampsia
Frequency of factor V, prothrombin and methylenetetrahydrofolate reductase gene variants in preeclampsia.
Pre-Eclampsia
Gene-environment interactions: a review of effects on reproduction and development.
Pre-Eclampsia
Genetic susceptibility to preeclampsia: roles of cytosineto-thymine substitution at nucleotide 677 of the gene for methylenetetrahydrofolate reductase, 68-base pair insertion at nucleotide 844 of the gene for cystathionine beta-synthase, and factor V Leiden mutation.
Pre-Eclampsia
Genetic thrombophilias and uterine artery Doppler velocimetry and preeclampsia.
Pre-Eclampsia
Genetic variants in 3'-UTRs of MTHFR in the pregnancies complicated with preeclampsia and bioinformatics analysis.
Pre-Eclampsia
Hyperhomocysteinemia is not sufficient to cause preeclampsia in an animal model: the importance of folate intake.
Pre-Eclampsia
Maternal and fetal variants of genetic thrombophilias and the risk of preeclampsia.
Pre-Eclampsia
Maternal and neonatal outcome of preeclamptic pregnancies: the potential roles of factor V Leiden mutation and 5,10 methylenetetrahydrofolate reductase.
Pre-Eclampsia
Maternal factor V Leiden mutation is associated with HELLP syndrome in Caucasian women.
Pre-Eclampsia
Meta-analysis of the methylenetetrahydrofolate reductase C677T polymorphism and susceptibility to pre-eclampsia.
Pre-Eclampsia
Methylene tetrahydrofolate reductase and methionine synthase gene polymorphisms as genetic determinants of pre-eclampsia.
Pre-Eclampsia
Methylenetetrahydrofolate Reductase (MTHFR) Gene C677T Polymorphism and Risk of Preeclampsia: An Updated Meta-analysis Based on 51 Studies.
Pre-Eclampsia
Methylenetetrahydrofolate reductase 677 C --> T polymorphism, plasma folate, vitamin B(12) concentrations, and risk of preeclampsia among black African women from Zimbabwe.
Pre-Eclampsia
Methylenetetrahydrofolate reductase 677 C-->T polymorphism and plasma folate in relation to pre-eclampsia risk among Peruvian women.
Pre-Eclampsia
Methylenetetrahydrofolate reductase C677T and glutathione S-transferase P1 A313G are associated with a reduced risk of preeclampsia in Maya-Mestizo women.
Pre-Eclampsia
Methylenetetrahydrofolate reductase C677T polymorphism and pregnancy complications.
Pre-Eclampsia
Methylenetetrahydrofolate Reductase Enzyme Level and Antioxidant Activity in Women with Gestational Hypertension and Pre-eclampsia in Lagos, Nigeria.
Pre-Eclampsia
Methylenetetrahydrofolate reductase gene C677T, A1298C polymorphisms and pre-eclampsia risk: a meta-analysis.
Pre-Eclampsia
Methylenetetrahydrofolate reductase gene polymorphisms in black South Africans and the association with preeclampsia.
Pre-Eclampsia
Methylenetetrahydrofolate reductase polymorphism, folate, and susceptibility to preeclampsia.
Pre-Eclampsia
Methylenetetrahydrofolate reductase polymorphisms in preeclampsia and the HELLP syndrome.
Pre-Eclampsia
MTHFR and F5 genetic variations have association with preeclampsia in Pakistani patients: a case control study.
Pre-Eclampsia
MTHFR C677T and eNOS G894T variants in preeclamptic women: Contribution to lipid peroxidation and oxidative stress.
Pre-Eclampsia
MTHFR C677T polymorphism is not associated with placental abruption or preeclampsia in Finnish women.
Pre-Eclampsia
Mutations in the gene for methylenetetrahydrofolate reductase, homocysteine levels, and vitamin status in women with a history of preeclampsia.
Pre-Eclampsia
Polymorphisms of the methylenetetrahydrofolate reductase gene (C677T and A1298C) in nulliparous women complicated with preeclampsia.
Pre-Eclampsia
Polymorphisms of the methylenetetrahydrofolate reductase gene (C677T and A1298C) in the placenta of pregnancies complicated with preeclampsia.
Pre-Eclampsia
Preeclampsia and its interaction with common variants in thrombophilia genes.
Pre-Eclampsia
Preeclampsia in North Indian women: the contribution of genetic polymorphisms.
Pre-Eclampsia
Relationship between polymorphisms in thrombophilic genes and preeclampsia in a Brazilian population.
Pre-Eclampsia
The 677 C-T methylenetetrahydrofolate reductase mutation does not predict increased maternal homocysteine during pregnancy.
Pre-Eclampsia
The antihypertensive MTHFR gene polymorphism rs17367504-G is a possible novel protective locus for preeclampsia.
Pre-Eclampsia
The association between maternal methylenetetrahydrofolate reductase C677T and A1298C polymorphism and birth defects and adverse pregnancy outcomes.
Pre-Eclampsia
The association between methylenetetrahydrofolate reductase C677T polymorphism and pre-eclampsia risk: appraisal of a recent meta-analysis.
Pre-Eclampsia
The association of the Placental MTHFR 3'-UTR polymorphisms, promoter methylation and MTHFR expression with Preeclampsia.
Pre-Eclampsia
The importance of MTHFR, MTR, MTRR and CSE expression levels in Caucasian women with preeclampsia.
Pre-Eclampsia
The methylenetetrahydrofolate reductase 677 C-->T polymorphism and preeclampsia in two populations.
Pre-Eclampsia
Thrombophilia is significantly associated with severe preeclampsia: results of a large-scale, case-controlled study.
Pre-Eclampsia
[Carriers of thrombophilic factor among women with preeclampsia (preliminary report)]
Pre-Eclampsia
[Folate-related processes in human placenta: gene expression, aminothiols, proliferation and apoptosis].
Pre-Eclampsia
[Folic acid levels, homocysteine and polymorphism of methylenetetrahydrofolate reductase enzyme (MTHFR) in patients with pre-eclampsia and eclampsia]
Pre-Eclampsia
[Genetic trombophilia and markers of endotelial activation in patients with preeclampsia]
Pre-Eclampsia
[Occurrence of gene mutations in factor V Leiden, prothrombin and methylenetetrahydrofolate reductase in patients with pre-eclampsia]
Pre-Eclampsia
[Screening for pre-eclampsia in a low-risk population at 24 weeks: uterine artery Doppler flow velocimetry and genetic variants of factor V, prothrombin and methylenetetrahydrofolate reductase]
Pre-Eclampsia
[The common C677T polymorphism in the methylenetetrahydrofolate reductase gene is associated with neural tube defects and preeclampsia]
Precursor Cell Lymphoblastic Leukemia-Lymphoma
5,10-Methylenetetrahydrofolate reductase polymorphisms and acute lymphoblastic leukemia risk: a meta-analysis.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
A meta-analysis of genotypes and haplotypes of methylenetetrahydrofolate reductase gene polymorphisms in acute lymphoblastic leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
A meta-analysis of MTHFR C677T and A1298C polymorphisms and risk of acute lymphoblastic leukemia in children.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
A systematic review and meta-analysis of MTHFR polymorphisms in methotrexate toxicity prediction in pediatric acute lymphoblastic leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Additional genetic risk factor for death in children with acute lymphoblastic leukemia: a common polymorphism of the MTHFR gene.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Assessment of the relationship between methylenetetrahydrofolate reductase polymorphism and acute lymphoblastic leukemia: Evidence from an updated meta-analysis.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Association between Methylenetetrahydrofolate Reductase (MTHFR) Gene Polymorphisms and Susceptibility to Childhood Acute Lymphoblastic Leukemia in an Iranian Population.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Association between methylenetetrahydrofolate reductase polymorphisms and the relapse of acute lymphoblastic leukemia: a meta-analysis.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Association between MTHFR C677T Polymorphism and Risk of Acute Lymphoblastic Leukemia: A Meta-Analysis Based on 51 Case-Control Studies.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Association between MTHFR microRNA binding site polymorphisms and methotrexate concentrations in Chinese pediatric patients with acute lymphoblastic leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Association between plasma homocysteine and riboflavin status in Acute Lymphoblastic Leukemia in children.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Association between the methylenetetrahydrofolate reductase polymorphisms and risk of acute lymphoblastic leukemia in serbian children.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Association of methylenetetrahydrofolate reductase gene-gene interaction and haplotype with susceptibility to acute lymphoblastic leukemia in Chinese children.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Association of the 5,10-methylenetetrahydrofolate reductase (MTHFR C677T and A1298C) polymorphisms in Korean patients with adult acute lymphoblastic leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Association of the methylenetetrahydrofolate reductase polymorphism in Korean patients with childhood acute lymphoblastic leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Cerebral venous sinus thrombosis in children with acute lymphoblastic leukemia carrying the MTHFR TT677 genotype and further prothrombotic risk factors.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Chapter 13 methylenetetrahydrofolate reductase, common polymorphisms, and relation to disease.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Combined 677CC/1298AC genotypes of methylenetetrahydrofolate reductase (MTHFR ) reduce susceptibility to precursor B lymphoblastic leukemia in a Chinese population.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Common gene polymorphisms in the metabolic folate and methylation pathway and the risk of acute lymphoblastic leukemia and non-Hodgkin's lymphoma in adults.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Comparative pharmacogenetic analysis of risk polymorphisms in Caucasian and Vietnamese children with acute lymphoblastic leukemia: prediction of therapeutic outcome?
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Comprehensive analysis of Methylenetetrahydrofolate reductase C677T in younger acute lymphoblastic leukemia patients: A single-center experience.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Do polymorphisms of 5,10-methylenetetrahydrofolate reductase (MTHFR) gene affect the risk of childhood acute lymphoblastic leukemia?
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Effect of folate status and methylenetetrahydrofolate reductase genotypes on the complications and outcome of high dose methotrexate chemotherapy in north Indian children with acute lymphoblastic leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Effects of methylenetetrahydrofolate reductase and reduced folate carrier 1 polymorphisms on high-dose methotrexate-induced toxicities in children with acute lymphoblastic leukemia or lymphoma.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Effects of methylenetetrahydrofolate reductase gene polymorphisms on toxicities during consolidation therapy in pediatric acute lymphoblastic leukemia in a Chinese population.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Folate pathway genetic polymorphisms are related to attention disorders in childhood leukemia survivors.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Folate related gene polymorphisms and susceptibility to develop childhood acute lymphoblastic leukaemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Functional variants of gene encoding folate metabolizing enzyme and methotrexate-related toxicity in children with acute lymphoblastic leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Genetic variation in the folate metabolic pathway and risk of childhood leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Genotyping of the MTHFR gene polymorphism, C677T in patients with leukemia by melting curve analysis.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Genotyping of two single nucleotide polymorphisms in 5,10-methylenetetrahydrofolate reductase by multiplex polymerase chain reaction and capillary electrophoresis.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Germline variation in the MTHFR and MTRR genes determines the nadir of bone density in pediatric acute lymphoblastic leukemia: A prospective study.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Heterozygosity at the TPMT gene locus, augmented by mutated MTHFR gene, predisposes to 6-MP related toxicities in childhood ALL patients.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
High dose methotrexate treatment in childhood ALL: pilot study on the impact of the MTHFR 677C>T and 1298A>C polymorphisms on MTX-related toxicity.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Impact of methylenetetrahydrofolate reductase (MTHFR) polymorphisms on methotrexate-induced toxicities in acute lymphoblastic leukemia: a meta-analysis.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Influence of genetic polymorphisms of FPGS, GGH, and MTHFR on serum methotrexate levels in Chinese children with acute lymphoblastic leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Influence of genetic polymorphisms on the risk of developing leukemia and on disease progression.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Influence of Methylenetetrahydrofolate Reductase C677T, A1298C, and G80A Polymorphisms on the Survival of Pediatric Patients with Acute Lymphoblastic Leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Influence of MTHFR and RFC1 polymorphisms on toxicities during maintenance chemotherapy for childhood acute lymphoblastic leukemia or lymphoma.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Influence of plasma methotrexate level and MTHFR genotype in Korean paediatric patients with acute lymphoblastic leukaemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Influence of variants in folate metabolism genes on 6-mercaptopurine induced toxicity during treatment for childhood acute lymphocytic leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Involvement of C677T MTHFR variant but not A1298C in methotrexate-induced toxicity in acute lymphoblastic leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Involvement of MTHFR and TPMT genes in susceptibility to childhood acute lymphoblastic leukemia (ALL) in Mexicans.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Involvement of MTHFR rs1801133 in the Susceptibility of Acute Lymphoblastic Leukemia: A Preliminary Study.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Lack of Association Between MTHFR C677T and A1298C Polymorphisms and Risk of Childhood Acute Lymphoblastic Leukemia in the Kurdish Population from Western Iran.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Lack of association between polymorphisms in genes MTHFR and MDR1 with risk of childhood acute lymphoblastic leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Maternal Haplotypes in DHFR Promoter and MTHFR Gene in Tuning Childhood Acute Lymphoblastic Leukemia Onset-Latency: Genetic/Epigenetic Mother/Child Dyad Study (GEMCDS).
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Meta-analyzing the link between MTHFR C677T genotype and susceptibility to childhood ALL.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Meta-prediction of MTHFR gene polymorphism-mutations, air pollution, and risks of leukemia among world populations.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Methotrexate consolidation treatment according to pharmacogenetics of MTHFR ameliorates event-free survival in childhood acute lymphoblastic leukaemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Methylene tetrahydrofolate reductase gene polymorphism in Egyptian children with acute lymphoblastic leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Methylenetetrahydrofolate reductase C677T and A1298C gene polymorphisms and therapy-related toxicity in children treated for acute lymphoblastic leukemia and non-Hodgkin lymphoma.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Methylenetetrahydrofolate reductase C677T and A1298C polymorphism and susceptibility to acute lymphoblastic leukemia in a cohort of Egyptian children.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Methylenetetrahydrofolate reductase C677T and overall survival in pediatric acute lymphoblastic leukemia: a systematic review.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Methylenetetrahydrofolate reductase C677T polymorphism does not alter folic acid deficiency-induced uracil incorporation into primary human lymphocyte DNA in vitro.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Methylenetetrahydrofolate reductase C677T polymorphism: association with risk for childhood acute lymphoblastic leukemia and response during the initial phase of chemotherapy in greek patients.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Methylenetetrahydrofolate reductase gene haplotypes affect toxicity during maintenance therapy for childhood acute lymphoblastic leukemia in Japanese patients.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Methylenetetrahydrofolate reductase gene polymorphisms and acute lymphoblastic leukemia risk: a meta-analysis based on 28case-control studies.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Methylenetetrahydrofolate reductase gene polymorphisms and risk of acute lymphoblastic leukemia in children.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Methylenetetrahydrofolate reductase gene polymorphisms: association with risk for pediatric acute lymphoblastic leukemia in north Indians.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Methylenetetrahydrofolate reductase genotypes do not play a role in acute lymphoblastic leukemia pathogenesis in the Italian population.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Methylenetetrahydrofolate reductase polymorphism C677T is a protective factor for pediatric acute lymphoblastic leukemia in the Chinese population: a meta-analysis.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Methylenetetrahydrofolate reductase polymorphisms and susceptibility to acute lymphoblastic leukemia in a Chinese population: a meta-analysis.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Methylenetetrahydrofolate reductase polymorphisms and therapy response in pediatric acute lymphoblastic leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Methylenetetrahydrofolate reductase polymorphisms, serum methylenetetrahydrofolate reductase levels, and risk of childhood acute lymphoblastic leukemia in a Chinese population.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Mexican Childhood Acute Lymphoblastic Leukemia: A Pilot Study of the MDR1 and MTHFR Gene Polymorphisms and Their Associations with Clinical Outcomes.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
MTHFR 677 (C-->T) polymorphism is not relevant for prognosis or therapy-associated toxicity in pediatric NHL: results from 484 patients of multicenter trial NHL-BFM 95.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
MTHFR 677 C>T genotype and adverse outcomes in treatment of childhood ALL: is the jury in?
Precursor Cell Lymphoblastic Leukemia-Lymphoma
MTHFR 677CC/1298CC genotypes are highly associated with chronic myelogenous leukemia: a case-control study in Korea.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
MTHFR 677T-1298C haplotype in acute lymphoblastic leukemia: Impact on methotrexate therapy.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
MTHFR C677T polymorphisms and childhood acute lymphoblastic leukemia: A meta-analysis.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
MTHFR gene polymorphism in acute lymphoblastic leukemia among North Indian children: a case-control study and meta-analysis updated from 2011.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
MTHFR Gene Polymorphisms and the Risk of Acute Lymphoblastic Leukemia in Adults and Children: A Case Control Study in India.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
MTHFR genetic polymorphisms and susceptibility to childhood acute lymphoblastic leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
MTHFR polymorphisms in childhood acute lymphoblastic leukemia: influence on methotrexate therapy.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
MTHFR polymorphisms' influence on outcome and toxicity in acute lymphoblastic leukemia patients.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
MTHFR single nucleotide polymorphism associated with working memory in pediatric medulloblastoma survivors.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
MTHFR-C677T Gene Polymorphism and Susceptibility to Acute Lymphoblastic Leukemia in Children: A Meta-Analysis.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
No evidence of association of methylenetetrahydrofolate reductase polymorphism with occurrence of second neoplasms after treatment of childhood leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Pharmacogenetic studies in children with acute lymphoblastic leukemia in Argentina.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Pharmacogenetic Variants in MTHFR Gene are Significant Predictors of Methotrexate Toxicities in Bangladeshi Patients With Acute Lymphoblastic Leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Polymorphisms in methylenetetrahydrofolate reductase and methotrexate sensitivity in childhood acute lymphoblastic leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Polymorphisms in the methylenetetrahydrofolate reductase gene are associated with susceptibility to acute leukemia in adults.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Polymorphisms in the MTHFR gene and their possible association with susceptibility to childhood acute lymphocytic leukemia in an Indian population.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Polymorphisms of 5,10-methylenetetrahydrofolate reductase and thymidylate synthase, dietary folate intake, and the risk of leukemia in adults.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Polymorphisms of methylenetetrahydrofolate reductase (MTHFR) and susceptibility to pediatric acute lymphoblastic leukemia in a German study population.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Polymorphisms of MTHFR and MTR genes are not related to susceptibility to childhood ALL in North India.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Polymorphisms of SLC19A1 80 G>A, MTHFR 677 C>T, and Tandem TS Repeats Influence Pharmacokinetics, Acute Liver Toxicity, and Vomiting in Children With Acute Lymphoblastic Leukemia Treated With High Doses of Methotrexate.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Prospective evaluation of the thrombotic risk in children with acute lymphoblastic leukemia carrying the MTHFR TT 677 genotype, the prothrombin G20210A variant, and further prothrombotic risk factors.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Reduced folate carrier and methylenetetrahydrofolate reductase gene polymorphisms: associations with clinical outcome in childhood acute lymphoblastic leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Role of folate status and methylenetetrahydrofolate reductase genotype on the toxicity and outcome of induction chemotherapy in children with acute lymphoblastic leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Role of MTHFR genetic polymorphisms in the susceptibility to childhood acute lymphoblastic leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Role of polymorphisms in MTHFR and MTHFD1 genes in the outcome of childhood acute lymphoblastic leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Rs4846049 Polymorphism at the 3'-UTR of MTHFR Gene: Association with Susceptibility to Childhood Acute Lymphoblastic Leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Subacute methotrexate neurotoxicity and cerebral venous sinus thrombosis in a 12-year-old with acute lymphoblastic leukemia and methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism: homocysteine-mediated methotrexate neurotoxicity via direct endothelial injury.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Synergistic effect of methyltetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphism as risk modifiers of pediatric acute lymphoblastic leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
The association between methylenetetrahydrofolate reductase C677 > T polymorphisms and risk of pediatric acute lymphoblastic leukemia in Asia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
The association of methylenetetrahydrofolate reductase genotypes with the risk of childhood leukemia in Taiwan.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
The Effect of RFC G80A Polymorphism in Cretan children with acute lymphoblastic leukemia and its interaction with MTHFR C677T and A1298C polymorphisms.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
The Influence of Genetic RFC1, MS and MTHFR Polymorphisms on the Risk of Acute Lymphoblastic Leukemia Relapse in Children and the Adverse Effects of Methotrexate.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
The methylenetetrahydrofolate reductase 677T-1298C haplotype is a risk factor for acute lymphoblastic leukemia in children.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
The methylenetetrahydrofolate reductase C677T gene polymorphism decreases the risk of childhood acute lymphocytic leukaemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
The MTHFR C677T and A1298C polymorphisms and susceptibility to childhood acute lymphoblastic leukemia in Portugal.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
The MTHFR C677T polymorphism and risk of acute lymphoblastic leukemia: an updated meta-analysis based on 37 case-control studies.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
The MTHFR polymorphism C677T in adult patients with acute lymphoblastic leukemia is associated with an increased prevalence of cytogenetic abnormalities.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
The potential effect of gender in combination with common genetic polymorphisms of drug-metabolizing enzymes on the risk of developing acute leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
The role of methylenetetrahydrofolate reductase in acute lymphoblastic leukemia in a Brazilian mixed population.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
The role of the methylenetetrahydrofolate reductase 677 and 1298 polymorphisms in Cretan children with acute lymphoblastic leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Thrombosis in children with hematologic malignancies.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
TPMT and MTHFR genotype is not associated with altered risk of thioguanine-related sinusoidal obstruction syndrome in pediatric acute lymphoblastic leukemia: A report from the Children's Oncology Group.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
TS Gene Polymorphisms Correlate with Susceptibility to Acute Lymphocytic Leukemia in Children.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Use of MTHFR C677T polymorphism and plasma pharmacokinetics to predict methotrexate toxicity in patients with acute lymphoblastic leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Variants of the MTHFR gene and susceptibility to acute lymphoblastic leukemia in children: A synthesis of genetic association studies.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
[A case of acute lymphoblastic leukemia of MTHFR C677T gene positive with methotrexate hypersensitivity was successfully rescued by hemodialysis].
Precursor Cell Lymphoblastic Leukemia-Lymphoma
[A new method for 5, 10-methylenetetrahydrofolate reductase single nucleotide polymorphisms genotyping used to study susceptibility of hematological malignancy]
Precursor Cell Lymphoblastic Leukemia-Lymphoma
[Association between mthfr gene polymorphisms and toxicity of HDMTX chemotherapy in acute lymphocytic leukemia]
Precursor Cell Lymphoblastic Leukemia-Lymphoma
[Association between the methylenetetrahydrofolate reductase gene polymorphisms and haplotype with toxicity response of high dose methotrexate chemotherapy].
Precursor Cell Lymphoblastic Leukemia-Lymphoma
[Association of single nucleotide polymorphism of methylenetetrahydrofolate reductase gene with susceptibility to acute leukemia].
Precursor Cell Lymphoblastic Leukemia-Lymphoma
[PROVISIONAL] The differential effects of the methylenetetrahydrofolate reductase polymorphisms (C677T and A1298C) on hematological malignancies among Latinos: a meta-analysis.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
[Relationship between the methylenetetrahydrofolate reductase gene polymorphism and adverse reactions of high-dose methotrexate in children with acute lymphocytic leukemia].
Pregnancy Complications
Association of MTHFR A1298C polymorphism (but not of MTHFR C677T) with elevated homocysteine levels and placental vasculopathies.
Pregnancy Complications
Association of Plasminogen Activator Inhibitor-1 Gene Polymorphisms and Methylene Tetrahydrofolate Reductase Polymorphisms with Spontaneous Miscarriages.
Pregnancy Complications
Associations between maternal methylenetetrahydrofolate reductase polymorphisms and adverse outcomes of pregnancy: the Hordaland Homocysteine Study.
Pregnancy Complications
Characterization of a pseudogene for murine methylenetetrahydrofolate reductase.
Pregnancy Complications
Detection of human genome mutations associated with pregnancy complications using 3-D microarray based on macroporous polymer monoliths.
Pregnancy Complications
Ethnic differences in the association of thrombophilic polymorphisms with obstetric complications in slovak and roma (gypsy) populations.
Pregnancy Complications
Evaluation of Factor V Leiden, Prothrombin and Methylenetetrahydrofolate Reductase Gene Mutations in Patients with Severe Pregnancy Complications in Northern Finland.
Pregnancy Complications
Factor V Leiden, pregnancy complications and adverse outcomes: the Hordaland Homocysteine Study.
Pregnancy Complications
Genetic thromobophilia in pregnancy: a case-control study among North Indian women.
Pregnancy Complications
Individualized Supplementation of Folic Acid According to Polymorphisms of Methylenetetrahydrofolate Reductase (MTHFR), Methionine Synthase Reductase (MTRR) Reduced Pregnant Complications.
Pregnancy Complications
Inherited thrombophilia and anticoagulant therapy for women with reproductive failure.
Pregnancy Complications
Low dietary folate and methylenetetrahydrofolate reductase deficiency may lead to pregnancy complications through modulation of ApoAI and IFN-? in spleen and placenta, and through reduction of methylation potential.
Pregnancy Complications
Methylenetetrahydrofolate reductase C677T polymorphism and pregnancy complications.
Pregnancy Complications
Methylenetetrahydrofolate reductase deficiency and low dietary folate increase embryonic delay and placental abnormalities in mice.
Pregnancy Complications
Methylenetetrahydrofolate reductase gene A1298C polymorphism and susceptibility to recurrent pregnancy loss: a meta-analysis.
Pregnancy Complications
MTHFR Gene variants C677T, A1298C and association with Down syndrome: A Case-control study from South India.
Pregnancy Complications
Multiple transcription start sites and alternative splicing in the methylenetetrahydrofolate reductase gene result in two enzyme isoforms.
Pregnancy Complications
Physiologic changes in homocysteine metabolism in pregnancy: A longitudinal study in Spain.
Pregnancy Complications
Polymorphisms in the methylenetetrahydrofolate reductase gene: clinical consequences.
Pregnancy Complications
Prevalence of the methylenetetrahydrofolate reductase 677C>T polymorphism in the pregnant women of Yunnan Province, China.
Pregnancy Complications
Pronto ThromboRisk--a novel primer-extension ELISA based assay for the detection of mutations associated with increased risk for thrombophilia.
Pregnancy Complications
The association between maternal methylenetetrahydrofolate reductase C677T and A1298C polymorphism and birth defects and adverse pregnancy outcomes.
Pregnancy Complications
The C677T methylenetetrahydrofolate reductase variant and third trimester obstetrical complications in women with unexplained elevations of maternal serum alpha-fetoprotein.
Pregnancy Complications
[Genetic mutations, acquired coagulation system disorders and obstetric pathology. Personal experience]
Pregnancy, High-Risk
The role of maternal homocysteine concentration in placenta-mediated complications: findings from the Ottawa and Kingston birth cohort.
Pregnancy, Tubal
Common Methylenetetrahydrofolate Reductase Polymorphisms (A1298C & C677T) in Ectopic Trophoblasts and Methotrexate Treatment Failure in Tubal Pregnancies.
Pregnancy, Tubal
Contribution of genetic polymorphism of methylene tetrahydrofolate reductase on the effect of methotrexate in ectopic pregnancy patients.
Premature Birth
Genetic polymorphism of MTHFR C677T with preterm birth and low birth weight susceptibility: a meta-analysis.
Premature Birth
Genetic variations of MTHFR gene and their association with preterm birth in Korean women.
Premature Birth
Methylenetetrahydrofolate reductase polymorphisms at 3'-untranslated region are associated with susceptibility to preterm birth.
Premature Birth
Thrombophilic polymorphisms--factor V Leiden, prothrombin G20210A, and methylenetetrahydrofolate reductase C677T mutations--and preterm birth.
Presbycusis
Polymorphisms in folate metabolism genes are associated with susceptibility to presbycusis.
Primary Ovarian Insufficiency
Association between premature ovarian failure, polymorphisms in MTHFR and MTRR genes and serum homocysteine concentration.
Primary Ovarian Insufficiency
Association of methylenetetrahydrofolate reductase (MTHFR 677C>T) and thymidylate synthase (TSER and TS 1494del6) polymorphisms with premature ovarian failure in Korean women.
Primary Ovarian Insufficiency
[Correlation Between MTHFR Mutation and Idiopathic Premature Ovarian Failure in Chinese Han Women].
Proctitis
Methionine synthase A2756G polymorphism may predict ulcerative colitis and methylenetetrahydrofolate reductase C677T pancolitis, in Central China.
Prostatic Diseases
MTHFR polymorphism and the risk of prostate cancer: a meta-analysis of case-control studies.
Prostatic Hyperplasia
Polymorphisms in the methylenetetrahydrofolate reductase gene and prostate cancer risk.
Prostatic Neoplasms
Analysis of relation between C677T genotype in MTHFR gene and prostatic cancer in Iranian males.
Prostatic Neoplasms
Association between MTHFR C677T Polymorphism and Risk of Prostate Cancer: Evidence from 22 Studies with 10,832 Cases and 11,993 Controls.
Prostatic Neoplasms
Association between MTHFR gene polymorphisms (C677T, A1298C) and genetic susceptibility to prostate cancer: a meta-analysis.
Prostatic Neoplasms
Associations between Intake of Folate, Methionine, and Vitamins B-12, B-6 and Prostate Cancer Risk in American Veterans.
Prostatic Neoplasms
Complex interaction between serum folate levels and genetic polymorphisms in folate pathway genes: biomarkers of prostate cancer aggressiveness.
Prostatic Neoplasms
Effects of the MTHFR C677T Polymorphism on Prostate Specific Antigen and Prostate Cancer.
Prostatic Neoplasms
Folate intake, alcohol consumption, and the methylenetetrahydrofolate reductase (MTHFR) C677T gene polymorphism: influence on prostate cancer risk and interactions.
Prostatic Neoplasms
Genetic Polymorphisms in MTHFR (C677T, A1298C), MTR (A2756G) and MTRR (A66G) Genes Associated With Pathological Characteristics of Prostate Cancer in the Ecuadorian Population.
Prostatic Neoplasms
Genetic variants in metabolizing genes NQO1, NQO2, MTHFR and risk of prostate cancer: a study from North India.
Prostatic Neoplasms
MTHFR c.677C>T Inhibits Cell Proliferation and Decreases Prostate Cancer Susceptibility in the Han Chinese Population in Shanghai.
Prostatic Neoplasms
MTHFR C677T polymorphism contributes to prostate cancer risk among Caucasians: A meta-analysis of 3511 cases and 2762 controls.
Prostatic Neoplasms
MTHFR polymorphism and the risk of prostate cancer: a meta-analysis of case-control studies.
Prostatic Neoplasms
No association of the MTHFR gene A1298C polymorphism with the risk of prostate cancer: A meta-analysis.
Prostatic Neoplasms
Polymorphisms in the methylenetetrahydrofolate reductase gene and prostate cancer risk.
Prostatic Neoplasms
Polymorphisms of methylenetetrahydrofolate reductase and the risk of prostate cancer: a nested case-control study.
Prostatic Neoplasms
Prognostic Relevance of Methylenetetrahydrofolate Reductase Polymorphisms for Prostate Cancer.
Prostatic Neoplasms
Relationship between methylenetetrahydrofolate reductase C677T and A1298C genotypes and haplotypes and prostate cancer risk and aggressiveness.
Prostatic Neoplasms
Relationship between three polymorphisms of methylenetetrahydrofolate reductase (MTHFR C677T, A1298C, and G1793A) gene and risk of prostate cancer: a case-control study.
Prostatic Neoplasms
Serum folate and vitamin B12 concentrations in relation to prostate cancer risk--a Norwegian population-based nested case-control study of 3000 cases and 3000 controls within the JANUS cohort.
Prostatic Neoplasms
Significant association of methylenetetrahydrofolate reductase single nucleotide polymorphisms with prostate cancer susceptibility in taiwan.
Prostatic Neoplasms
The analysis of the relationship between A1298C and C677T polymorphisms of the MTHFR gene with prostate cancer in Eskisehir population.
Prostatic Neoplasms
The methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and cancer risk: the Croatian case-control study.
Prostatic Neoplasms
The MTHFR 677C-->T polymorphism and risk of prostate cancer: results from the CAPS study.
Prostatic Neoplasms
The MTHFR C677T Polymorphism and Prostate Cancer Risk: New Findings from a Meta-analysis of 7306 Cases and 8062 Controls.
Prostatic Neoplasms
The protective effect of methylenetetrahydrofolate reductase C677T polymorphism against prostate cancer risk: Evidence from 23 case-control studies.
Protein C Deficiency
Does thrombophilia play an aetiological role in Legg-Calvé-Perthes disease?
Protein C Deficiency
Etiology of hypercoagulable state in women with recurrent fetal loss without other causes of miscarriage from Southern Italy: new clinical target for antithrombotic therapy.
Protein C Deficiency
Evaluation of cerebral venous thrombosis secondary to oral contraceptive use in adolescents.
Protein C Deficiency
How strong is the association between maternal thrombophilia and adverse pregnancy outcome? A systematic review.
Protein C Deficiency
Impact of thrombophilia on risk of arterial ischemic stroke or cerebral sinovenous thrombosis in neonates and children: a systematic review and meta-analysis of observational studies.
Protein C Deficiency
Ischemic stroke subtypes and thrombophilia in young and elderly Brazilian stroke patients admitted to a rehabilitation hospital.
Protein C Deficiency
Lipoprotein (a) and genetic polymorphisms of clotting factor V, prothrombin, and methylenetetrahydrofolate reductase are risk factors of spontaneous ischemic stroke in childhood.
Protein C Deficiency
Livedoid vasculopathy and hypercoagulability in a patient with primary Sjögren's syndrome.
Protein C Deficiency
Myocardial infarction and venous thrombosis in a 42-year old woman with heterozygous methylenetetrahydrofolate reductase (MTHRF) gene mutation, hyperhomocysteinemia, and protein C deficiency.
Protein C Deficiency
Prospective evaluation of the thrombotic risk in children with acute lymphoblastic leukemia carrying the MTHFR TT 677 genotype, the prothrombin G20210A variant, and further prothrombotic risk factors.
Protein C Deficiency
Recurrent miscarriage syndrome and infertility due to blood coagulation protein/platelet defects: a review and update.
Protein C Deficiency
Review of Management and Outcomes in Women with Thrombophilia Risk during Pregnancy at a Single Institution.
Protein C Deficiency
Severe purpura fulminans due to coexistence of homozygous protein C deficiency and homozygous methylenetetrahydrofolate reductase mutation.
Protein C Deficiency
The relationship of the factor V Leiden mutation and pregnancy outcomes for mother and fetus.
Protein C Deficiency
Thrombophilia and first arterial ischaemic stroke: a systematic review.
Protein C Deficiency
Thrombophilic risk factors in hemodialysis: Association with early vascular access occlusion and patient survival in long-term follow-up.
Protein C Deficiency
Treatment of adverse perinatal outcome in inherited thrombophilias: a clinical study.
Protein Deficiency
Lack of Association between Recurrent Pregnancy Loss and Inherited Thrombophilia in a Group of Colombian Patients.
Protein Deficiency
Primary thrombophilia in Mexico: a single tertiary referral hospital experience.
Protein S Deficiency
Association of hereditary thrombophilia with intrauterine growth restriction.
Protein S Deficiency
Etiology of hypercoagulable state in women with recurrent fetal loss without other causes of miscarriage from Southern Italy: new clinical target for antithrombotic therapy.
Protein S Deficiency
FV Leiden mutation and risk of recurrent venous thromboembolism in Serbian population.
Protein S Deficiency
How strong is the association between maternal thrombophilia and adverse pregnancy outcome? A systematic review.
Protein S Deficiency
Impact of thrombophilia on risk of arterial ischemic stroke or cerebral sinovenous thrombosis in neonates and children: a systematic review and meta-analysis of observational studies.
Protein S Deficiency
Implantation of left ventricular assist device complicated by undiagnosed thrombophilia.
Protein S Deficiency
Inherited thrombophilia and anticoagulant therapy for women with reproductive failure.
Protein S Deficiency
Ischemic stroke subtypes and thrombophilia in young and elderly Brazilian stroke patients admitted to a rehabilitation hospital.
Protein S Deficiency
Outcome of kidney transplantation in patients with inherited thrombophilia: data of a prospective study.
Protein S Deficiency
Recurrent miscarriage syndrome and infertility due to blood coagulation protein/platelet defects: a review and update.
Protein S Deficiency
Review article: the aetiology of primary Budd-Chiari syndrome - differences between the West and China.
Protein S Deficiency
Review of Management and Outcomes in Women with Thrombophilia Risk during Pregnancy at a Single Institution.
Protein S Deficiency
Sequential multiple retinal vein occlusions and transient ischemic attack in MTHFR polymorphism and protein S deficiency.
Protein S Deficiency
The relationship between pregnancy induced hypertension and congenital thrombophilia.
Protein S Deficiency
The relationship of the factor V Leiden mutation and pregnancy outcomes for mother and fetus.
Protein S Deficiency
Thrombophilia and first arterial ischaemic stroke: a systematic review.
Protein S Deficiency
Thrombophilic risk factors in hemodialysis: Association with early vascular access occlusion and patient survival in long-term follow-up.
Protein S Deficiency
Treatment of adverse perinatal outcome in inherited thrombophilias: a clinical study.
Protein S Deficiency
Use of hyperbaric oxygen therapy of purpura fulminans in an extremely low birth weight preterm: A case report.
Protein S Deficiency
Warfarin skin necrosis associated with protein S deficiency and a mutation in the methylenetetrahydrofolate reductase gene.
Proteinuria
Association of methylenetetrahydrofolate reductase T677 allele with early development of chronic allograft nephropathy.
Proteinuria
Fingertips ischemia, nephroangiosclerosis, and focal segmental glomerulosclerosis: is genetic thrombophilia the unique explanation?
Pseudarthrosis
[Methylenetetrahydrofolate reductase polymorphism C677T in patients with consolidated fractures and pseudarthrosis of long bones: relationship with homocystein and inflammatory mediators].
Pseudoxanthoma Elasticum
Can APOE and MTHFR polymorphisms have an influence on the severity of cardiovascular manifestations in Italian Pseudoxanthoma elasticum affected patients?
Pseudoxanthoma Elasticum
Clinical and Genetic Heterogeneity in a Large Family with Pseudoxanthoma Elasticum: MTHFR and SERPINE1 Variants as Possible Disease Modifiers in Developing Ischemic Stroke.
Psoriasis
Association between methylenetetrahydrofolate reductase C677T polymorphism and psoriasis: A meta-analysis.
Psoriasis
Association between MTHFR 677C/T polymorphism and psoriasis risk: a meta-analysis.
Psoriasis
Goeckerman Therapy of Psoriasis: Genotoxicity, Dietary Micronutrients, Homocysteine, and MTHFR Gene Polymorphisms.
Psoriasis
Homocysteine: A Potential Common Route for Cardiovascular Risk and DNA Methylation in Psoriasis.
Psoriasis
Interaction of MTHFR gene with smoking and alcohol use and haplotype combination susceptibility to psoriasis in Chinese population.
Psoriasis
Methylenetetrahydrofolate reductase (MTHFR) 677C>T gene polymorphism as a possible factor for reducing clinical severity of psoriasis.
Psoriasis
Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism in psoriasis in southern Turkey.
Psoriasis
Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism: epidemiology, metabolism and the associated diseases.
Psoriasis
Methylenetetrahydrofolate Reductase C677T Gene Polymorphism as Risk Factor for Psoriasis in Saudis.
Psoriasis
Outcomes of methotrexate therapy for psoriasis and relationship to genetic polymorphisms.
Psoriasis
Possible association between germline methylenetetrahydrofolate reductase gene polymorphisms and psoriasis risk in a Turkish population.
Psoriasis
Study of the relationship between psoriasis and the polymorphic site C677T of methylenetetrahydrofolate reductase.
Psoriasis
The methylenetetrahydrofolate reductase 677C>T gene polymorphism is not associated with chronic plaque psoriasis.
Pulmonary Embolism
Aortic Thrombus and Acute Pulmonary Embolism in an Individual Heterozygous for the MTHFR C677-T Mutation.
Pulmonary Embolism
Aortic thrombus and acute pulmonary embolism in an individual heterozygous for the MTHFR C677T mutation.
Pulmonary Embolism
Association of folate metabolism gene polymorphisms and haplotype combination with pulmonary embolism risk in Chinese Han population.
Pulmonary Embolism
Association of folate metabolism gene polymorphisms and pulmonary embolism: A case-control study of West-Siberian population.
Pulmonary Embolism
Contraception-related deep venous thrombosis and pulmonary embolism in a 17-Year-old girl heterozygous for factor V leiden, prothrombin G20210A mutation, MTHFR C677T and homozygous for PAI-1 mutation: report of a family with multiple genetic risk factors and review of the literature.
Pulmonary Embolism
Correlations between methylenetetrahydrofolate reductase gene polymorphisms and venous thromboembolism: A meta-analysis of 99 genetic association studies.
Pulmonary Embolism
Factor V gene G1691A mutation, prothrombin gene G20210A mutation, and MTHFR gene C677T mutation are not risk factors for pulmonary thromboembolism in Chinese population.
Pulmonary Embolism
Frequency of thrombophilia-related genetic variations in patients with idiopathic pulmonary embolism in an urban emergency department.
Pulmonary Embolism
Massive Pulmonary Embolism Associated With Factor V Leiden, Prothrombin, and Methylenetetrahydrofolate Reductase Gene Mutations in a Young Patient on Oral Contraceptive Pills: A Case Report.
Pulmonary Embolism
Massive pulmonary embolism in a Lebanese patient doubly heterozygous for MTHFR and Factor V Leiden presenting with syncope and treated with tenecteplase.
Pulmonary Embolism
Molecular Analysis of Prothrombotic Gene Variants in Venous Thrombosis: A Potential Role for Sex and Thrombotic Localization.
Pulmonary Embolism
Polymorphisms C677T and A1298C of MTHFR Gene: Homocysteine Levels and Prothrombotic Biomarkers in Coronary and Pulmonary Thromboembolic Disease.
Pulmonary Embolism
Pulmonary embolism and premature labor in a patient with both factor V Leiden mutation and methylenetetrahydrofolate reductase gene C677T mutation.
Pulmonary Embolism
Pulmonary Embolism in a Sarcoidosis Patient Double Heterozygous for Methylenetetrahydrofolate Reductase Gene Polymorphisms and Factor V Leiden and Homozygous for the D-Allele of Angiotensin Converting Enzyme Gene.
Pulmonary Embolism
Pulmonary Thromboembolism Following Radio-Frequency Ablation of the Atrioventricular Node in a Patient Heterozygous for the Factor V Leiden and the Mthfr C677T Mutations.
Pulmonary Embolism
Rare variants in MTHFR predispose to occurrence and recurrence of pulmonary embolism.
Pulmonary Embolism
Severe methylenetetrahydrofolate reductase deficiency revealed by a pulmonary embolism in a young adult.
Pulmonary Embolism
ST-elevation myocardial infarction, pulmonary embolism, and cerebral ischemic stroke in a patient with critically low levels of natural anticoagulants.
Pulmonary Embolism
The importance of MTHFR C677T/A1298C combined polymorphisms in pulmonary embolism in Turkish population.
Pulmonary Embolism
Thrombophilia-related genetic variations in patients with pulmonary embolism in the main teaching hospital in Jordan.
Purpura
METHYLENETETRAHYDROFOLATE REDUCTASE C677T POLYMORPHISM IN PATIENTS WITH HENOCH-SCHÖNLEIN PURPURA.
Purpura Fulminans
Purpura Fulminans as the presenting manifestation in a patient with homozygous methylenetetrahydrofolate reductase gene mutation.
Purpura Fulminans
Severe purpura fulminans due to coexistence of homozygous protein C deficiency and homozygous methylenetetrahydrofolate reductase mutation.
Pyoderma
Pyoderma gangrenosum-like lesion secondary to methylenetetrahydrofolate reductase mutation: an unusual presentation of a rare disease.
Pyoderma Gangrenosum
Hydroxyurea-Induced Leg Ulceration in a Patient With a Homozygous MTHFR Polymorphism Misdiagnosed as Pyoderma Gangrenosum.
Pyoderma Gangrenosum
Pyoderma gangrenosum-like lesion secondary to methylenetetrahydrofolate reductase mutation: an unusual presentation of a rare disease.
Pyoderma Gangrenosum
Skin ulcers mimicking pyoderma gangrenosum in a patient with MTHFR polymorphism.
Pyoderma Gangrenosum
The use of B vitamins for cutaneous ulcerations mimicking pyoderma gangrenosum in patients with MTHFR polymorphism.
Pyruvate Dehydrogenase Complex Deficiency Disease
Diagnostic yield of genetic testing in epileptic encephalopathy in childhood.
pyruvate kinase deficiency
Moya moya syndrome in a child with pyruvate kinase deficiency and combined prothrombotic factors.
Quadriplegia
Associations between inherited thrombophilias, gestational age, and cerebral palsy.
Radiation Pneumonitis
A single-nucleotide polymorphism in the MTHFR (methylene tetrahydrofolate reductase) gene is associated with risk of radiation pneumonitis in lung cancer patients treated with thoracic radiation therapy.
Radiation Pneumonitis
Genetic Variants in MTHFR Gene Predict ? 2 Radiation Pneumonitis in Esophageal Squamous Cell Carcinoma Patients Treated with Thoracic Radiotherapy.
Rectal Neoplasms
A common variant in MTHFR influences response to chemoradiotherapy and recurrence of rectal cancer.
Rectal Neoplasms
A haplotype of the methylenetetrahydrofolate reductase gene predicts poor tumor response in rectal cancer patients receiving preoperative chemoradiation.
Rectal Neoplasms
Associations between 5,10-methylenetetrahydrofolate reductase codon 677 and 1298 genetic polymorphisms and environmental factors with reference to susceptibility to colorectal cancer: a case-control study in an Indian population.
Rectal Neoplasms
Candidate pathway polymorphisms in one-carbon metabolism and risk of rectal tumor mutations.
Rectal Neoplasms
Dietary intake of folate and co-factors in folate metabolism, MTHFR polymorphisms, and reduced rectal cancer.
Rectal Neoplasms
Diets, polymorphisms of methylenetetrahydrofolate reductase, and the susceptibility of colon cancer and rectal cancer.
Rectal Neoplasms
Gene polymorphisms involved in folate and methionine metabolism and increased risk of sporadic colorectal adenocarcinoma.
Rectal Neoplasms
Genetic polymorphisms of methylenetetrahydrofolate reductase and susceptibility to colorectal cancer.
Rectal Neoplasms
Germline and somatic genetic predictors of pathological response in neoadjuvant settings of rectal and esophageal cancers: systematic review and meta-analysis.
Rectal Neoplasms
Glutathione S-transferase P1 Ile105Val polymorphism is associated with haematological toxicity in elderly rectal cancer patients receiving preoperative chemoradiotherapy.
Rectal Neoplasms
Immunohistochemical and genetic prognostic factors of neoadjuvant chemoradiotherapy effic?cy in personalized treatment of local advanced rectal cancer.
Rectal Neoplasms
Methylenetetrahydrofolate reductase genetic polymorphisms and toxicity to 5-FU-based chemoradiation in rectal cancer.
Rectal Neoplasms
Methylenetetrahydrofolate reductase polymorphism, alcohol intake, and risks of colon and rectal cancers in Korea.
Rectal Neoplasms
MTHFR, TSER and DPYD gene mutation is associated with toxicity and response in pre-operative chemo-radiotherapy for local advanced rectal cancer.
Rectal Neoplasms
Nutrients in Folate-Mediated, One-Carbon Metabolism and the Risk of Rectal Tumors in Men and Women.
Rectal Neoplasms
Polymorphisms of MTHFR C677T and A1298C associated with survival in patients with colorectal cancer treated with 5-fluorouracil-based chemotherapy.
Rectal Neoplasms
Risk factors for rectal cancer and methylenetetrahydrofolate reductase polymorphisms in a population in Northeast Thailand.
Rectal Neoplasms
SHMT1 1420 and MTHFR 677 variants are associated with rectal but not colon cancer.
Renal Artery Obstruction
Genetic variants in hypertensive patients with coronary artery disease and coexisting atheromatous renal artery stenosis.
Renal Insufficiency
Genetic Predisposition for Development of Nephropathy in Type 2 Diabetes Mellitus.
Renal Insufficiency
Homocysteine, endothelial dysfunction, and coronary artery disease: emerging strategy for secondary prevention.
Renal Insufficiency
Homocysteine, folate, vitamin B12 levels, and C677T MTHFR mutation in children with renal failure.
Renal Insufficiency
Homocysteine, methylenetetrahydrofolate reductase polymorphism, antiphospholipid antibodies, and thromboembolic events in systemic lupus erythematosus: a retrospective cohort study.
Renal Insufficiency
Hyperhomocysteinemia and polymorphisms of the methylenetetrahydrofolate gene in hemodialysis and peritoneal dialysis patients.
Renal Insufficiency
Methylenetetrahydrofolate Reductase gene polymorphism in patients receiving hemodialysis.
Renal Insufficiency
Methylenetetrahydrofolate reductase gene polymorphisms in essential hypertension relation: with the development of hypertensive end-stage renal disease.
Renal Insufficiency
Methylenetetrahydrofolate-reductase gene C677T variant and kidney-transplant survival.
Renal Insufficiency
Relationship of MTHFR gene polymorphisms with renal and cardiac disease.
Renal Insufficiency
Renal failure after high-dose methotrexate in a child homozygous for MTHFR C677T polymorphism.
Renal Insufficiency
Renal Insufficiency in Non-Diabetic Subjects: Relationship of MTHFR C677t Gene Polymorphism and Left Ventricular Hypertrophy.
Renal Insufficiency
Severe atherosclerosis in rheumatoid arthritis and hyperhomocysteinemia: is there a link?
Renal Insufficiency
The association between end-stage diabetic nephropathy and methylenetetrahydrofolate reductase genotype with macroangiopathy in type 2 diabetes mellitus.
Renal Insufficiency
The C677T methylenetetrahydrofolate reductase gene mutation in hemodialysis patients.
Renal Insufficiency
The common mutations C677T and A1298C in the human methylenetetrahydrofolate reductase gene are associated with hyperhomocysteinemia and cardiovascular disease in hemodialysis patients.
Renal Insufficiency, Chronic
Decisive evidence corroborates a null relationship between MTHFR C677T and chronic kidney disease: A case-control study and a meta-analysis.
Renal Insufficiency, Chronic
Effect of the MTHFR C677T and A1298C polymorphisms on survival in patients with advanced CKD and ESRD: a prospective study.
Renal Insufficiency, Chronic
Effects of Italian Mediterranean organic diet vs. low-protein diet in nephropathic patients according to MTHFR genotypes.
Renal Insufficiency, Chronic
Endothelial nitric oxide synthetase, methylenetetrahydrofolate reductase polymorphisms, and cardiovascular complications in Tunisian patients with nondiabetic renal disease.
Renal Insufficiency, Chronic
Methylenetetrahydrofolate reductase C677T polymorphism is associated with estimated glomerular filtration rate in hypertensive Chinese males.
Renal Insufficiency, Chronic
MTHFR, MTR and MTRR polymorphisms and risk of chronic kidney disease in Japanese: cross-sectional data from the J-MICC Study.
Renal Insufficiency, Chronic
Relationship Between Gene Polymorphism of Methylenetetrahydrofolate Reductase C677T and Left Ventricular Hypertrophy in Chinese Patients with Chronic Kidney Disease.
Renal Insufficiency, Chronic
[Remodeling of the cardiovascular system and development of chronic kidney disease in patients with metabolic syndrome and obesity: role of eNOS, subunit p22-phox of NADPH-oxidase and MTHFR genes].
Retinal Artery Occlusion
Branch retinal artery occlusion associated with compound heterozygous genotype for methylenetetrahydrofolate reductase.
Retinal Artery Occlusion
Cumulative visual impact of two coagulability disorders: A case report.
Retinal Artery Occlusion
Hyperbaric oxygen therapy in branch retinal artery occlusion in a 15-year-old boy with methylenetetrahydrofolate reductase mutation.
Retinal Artery Occlusion
The role of hyperhomocysteinemia and methylenetetrahydrofolate reductase (MTHFR) C677T mutation in patients with retinal artery occlusion.
Retinal Vein Occlusion
A 31 year old woman with essential hypertension grade III and branch retinal vein occlusion with homozygous C677T MTHFR hyperhomocysteinemia and high Lp(a) levels.
Retinal Vein Occlusion
Association of methylenetetrahydrofolate reductase (A1298C and C677T) polymorphisms with retinal vein occlusion in Tunisian patients.
Retinal Vein Occlusion
Association of retinal vein occlusion, homocysteine, and the thrombophilic mutations in a Turkish population: A case-control study.
Retinal Vein Occlusion
Association study of high-frequency variants of MTHFR gene with retinal vein occlusion in a Spanish population.
Retinal Vein Occlusion
Bilateral retinal vein occlusion associated with 5,10-methylenetetrahydrofolate reductase mutation.
Retinal Vein Occlusion
Genetic determinants of fasting and post-methionine hyperhomocysteinemia in patients with retinal vein occlusion.
Retinal Vein Occlusion
Homocysteine, methylenetetrahydrofolate reductase C677T polymorphism, and risk of retinal vein occlusion: a meta-analysis.
Retinal Vein Occlusion
Homocysteine, methylenetetrahydrofolate reductase C677T polymorphism, and risk of retinal vein occlusion: an updated meta-analysis.
Retinal Vein Occlusion
Homocysteine, MTHFR C677T gene polymorphism, folic acid and vitamin B 12 in patients with retinal vein occlusion.
Retinal Vein Occlusion
Hyperhomocyst(e)inemia and MTHFR C677T genotypes in patients with central retinal vein occlusion.
Retinal Vein Occlusion
Hyperhomocyst(e)inemia, but not methylenetetrahydrofolate reductase C677T mutation, as a risk factor in branch retinal vein occlusion.
Retinal Vein Occlusion
Hyperhomocysteinemia and C677T MTHFR Genotype in Patients With Retinal Vein Thrombosis.
Retinal Vein Occlusion
Hyperhomocysteinemia and the methylenetetrahydrofolate reductase 677C-T mutation in patients under 50 years of age affected by central retinal vein occlusion.
Retinal Vein Occlusion
Hyperhomocysteinemia and the MTHFR C677T mutation in central retinal vein occlusion.
Retinal Vein Occlusion
Hyperhomocysteinemia in central retinal vein occlusion in young adults.
Retinal Vein Occlusion
Investigation of methylenetetrahydrofolate reductase C677T and factor V Leiden mutation as a genetic marker for retinal vein occlusion.
Retinal Vein Occlusion
MEK Inhibitor-Associated Central Retinal Vein Occlusion Associated with Hyperhomocysteinemia and MTHFR Variants.
Retinal Vein Occlusion
Methylenetetrahydrofolate reductase C677T mutation and risk of retinal vein thrombosis.
Retinal Vein Occlusion
Methylenetetrahydrofolate reductase polymorphisms as risk factors for retinal venous occlusive disease: A literature review.
Retinal Vein Occlusion
Molecular Analysis of Prothrombotic Gene Variants in Venous Thrombosis: A Potential Role for Sex and Thrombotic Localization.
Retinal Vein Occlusion
MTHFR C677T homozygous mutation in a patient with pigmentary glaucoma and central retinal vein occlusion.
Retinal Vein Occlusion
MTHFR C677T mutation in central retinal vein occlusion: a case-control study in Chinese population.
Retinal Vein Occlusion
MTHFR C677T mutation, factor II G20210A mutation and factor V Leiden as risks factor for youth retinal vein occlusion.
Retinal Vein Occlusion
PO-57 - Problems of diagnostics of rare localizations thrombosis in cancer patients.
Retinal Vein Occlusion
Retinal vein occlusion associated with methylenetetrahydrofolate reductase mutation.
Retinal Vein Occlusion
Sequential multiple retinal vein occlusions and transient ischemic attack in MTHFR polymorphism and protein S deficiency.
Retinoblastoma
Association of MTHFR 677C>T, 1298A>C and MTR 2756A>G Polymorphisms with Risk of Retinoblastoma.
Retinoblastoma
Association of MTHFR 677C?>?T, 1298A?>?C and MTR 2756A?>?G Polymorphisms with Susceptibility to Childhood Retinoblastoma: A Systematic Review and Met-Analysis.
Retinoblastoma
Association study of the common polymorphisms in the folate-methionine pathway with retinoblastoma.
Retinoblastoma
MTR polymorphic variant A2756G and retinoblastoma risk in Brazilian children.
Retinoblastoma
Oxidative Stress and Polymorphism in MTHFR SNPs (677 and 1298) in Paternal Sperm DNA is Associated with an Increased Risk of Retinoblastoma in Their Children: A Case-Control Study.
Retinoblastoma
Polymorphism in MTHFR (at SNPs 677 and 1298) in Paternal Sperm DNA and Risk of Retinoblastoma in their Children.
Retinoblastoma
Risk of retinoblastoma is associated with a maternal polymorphism in dihydrofolatereductase (DHFR) and prenatal folic acid intake.
Retinopathy of Prematurity
Evaluation of Factor V Leiden, Prothrombin G20210A, MTHFR C677T and MTHFR A1298C gene polymorphisms in retinopathy of prematurity in a Turkish cohort.
Rheumatic Heart Disease
The MTHFR C677T polymorphism is associated with mitral valve rheumatic heart disease.
Rhinitis, Allergic
Methylenetetrahydrofolate Reductase gene polymorphism in children with allergic rhinitis.
Riboflavin Deficiency
Methylenetetrahydrofolate reductase C677T polymorphism, folic acid and riboflavin are important determinants of genome stability in cultured human lymphocytes.
Sacroiliitis
Sacroiliitis and muscle cramps in a healthy young man: some spearhead on MTHFR mutations.
Sarcoidosis
Pulmonary Embolism in a Sarcoidosis Patient Double Heterozygous for Methylenetetrahydrofolate Reductase Gene Polymorphisms and Factor V Leiden and Homozygous for the D-Allele of Angiotensin Converting Enzyme Gene.
Sarcoma
Methylenetetrahydrofolate reductase C677T gene polymorphism in osteosarcoma and chondrosarcoma patients.
Sarcopenia
The MTHFR gene polymorphism is associated with lean body mass but not fat body mass.
Scleroderma, Systemic
Plasma homocysteine levels, the prevalence of methylenetetrahydrofolate reductase gene C677T polymorphism and macrovascular disorders in systemic sclerosis: risk factors for accelerated macrovascular damage?
Scoliosis
Severe scoliosis in a patient with severe methylenetetrahydrofolate reductase deficiency.
Seizures
Adolescence/adult onset MTHFR deficiency may manifest as isolated and treatable distinct neuro-psychiatric syndromes.
Seizures
Complete deficiency of methylenetetrahydrofolate reductase in mice is associated with impaired retinal function and variable mortality, hematological profiles, and reproductive outcomes.
Seizures
Interictal epileptiform discharges on electroencephalography in children with methylenetetrahydrofolate reductase (MTHFR) polymorphisms.
Seizures
Methylenetetrahydrofolate reductase C677T-polymorphism and its association with alcohol withdrawal seizure.
Seizures
Methylenetetrahydrofolate reductase deficiency in a patient with phenotypic findings of Angelman syndrome.
Seizures
Neonatal sinovenous thrombosis associated with homozygous thermolabile methylenetetrahydrofolate reductase in both mother and infant.
Seizures
Prenatal diagnosis for severe methylenetetrahydrofolate reductase deficiency by linkage analysis and enzymatic assay.
Sepsis
Portal Vein Thrombosis in a Preterm Newborn with Mutation of the MTHFR and PAI-1 Genes and Sepsis by Candida parapsilosis.
Sexually Transmitted Diseases
The Impact of MTHFR 1298 A?>?C and 677 C?>?T Gene Polymorphisms as Susceptibility Risk Factors in Cervical Intraepithelial Neoplasia Related to HPV and Sexually Transmitted Infections.
Shoulder Pain
Avascular Necrosis of the Humeral Head in a Patient with Methylenetetrahydrofolate Reductase 1 Gene Polymorphism: A Case Report.
Sickle Cell Trait
Recurrent cerebral venous thrombosis associated with heterozygote methylenetetrahydrofolate reductase C677T mutation and sickle cell trait without homocysteinemia: an autopsy case report and review of literature.
Sinus Thrombosis, Intracranial
Bilateral transverse sinus thrombosis secondary to a homozygous C677T MTHFR gene mutation.
Sinus Thrombosis, Intracranial
Cerebral Venous and Sinus Thrombosis and Thrombophilic Mutations in Western Iran: Association With Factor V Leiden.
Sinus Thrombosis, Intracranial
Cerebral venous sinus thrombosis in children with acute lymphoblastic leukemia carrying the MTHFR TT677 genotype and further prothrombotic risk factors.
Sinus Thrombosis, Intracranial
Cerebral Venous Sinus Thrombosis Presenting as Transient Ischemic Attacks in a Case With Homozygous Mutations of MTHFR A1298C and CG677T.
Sinus Thrombosis, Intracranial
Factor V Leiden, factor V Cambridge, factor II GA20210, and methylenetetrahydrofolate reductase in cerebral venous and sinus thrombosis: A case-control study.
Sinus Thrombosis, Intracranial
Heterozygous MTHFR A1298C Mutation causing Cerebral Venous Sinus Thrombosis.
Sinus Thrombosis, Intracranial
Inherited thrombophilic factors do not increase central venous catheter blockage in children with malignancy.
Sinus Thrombosis, Intracranial
MTHFR Gene Polymorphisms and Cardiovascular Risk Factors, Clinical-Imagistic Features and Outcome in Cerebral Venous Sinus Thrombosis.
Sinus Thrombosis, Intracranial
Subacute methotrexate neurotoxicity and cerebral venous sinus thrombosis in a 12-year-old with acute lymphoblastic leukemia and methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism: homocysteine-mediated methotrexate neurotoxicity via direct endothelial injury.
Sjogren's Syndrome
MTHFR gene variants and non-MALT lymphoma development in primary Sjogren's syndrome.
Skin Abnormalities
A newborn case with perinatal-lethal Gaucher disease due to R463H homozygosity complicated by C677T homozygosity in the MTHFR gene.
Skin Diseases
Global and gene-specific DNA methylation and hydroxymethylation in human skin exposed and not exposed to sun radiation.
Skin Neoplasms
Methylenetetrahydrofolate reductase gene polymorphisms and skin cancer risk: a meta-analysis.
Skin Neoplasms
Polymorphisms of 5,10-methylenetetrahydrofolate reductase and thymidylate synthase in squamous cell carcinoma and basal cell carcinoma of the skin.
Skin Ulcer
Skin ulcers mimicking pyoderma gangrenosum in a patient with MTHFR polymorphism.
Sleep Apnea, Obstructive
Nutrigenetic genotyping study in relation to Sleep Apnea Clinical Score.
Sleep Initiation and Maintenance Disorders
Interaction between methylenetetrahydrofolate reductase C677T gene polymorphism and sleep duration on risk of stroke pathogenesis.
Small Cell Lung Carcinoma
Hierarchical clustering of lung cancer cell lines using DNA methylation markers.
Small Cell Lung Carcinoma
Methylenetetrahydrofolate reductase gene C677T and A1298C polymorphisms in patients with small cell and non-small cell lung cancer.
Spastic Paraplegia, Hereditary
Severe 5,10-methylenetetrahydrofolate reductase deficiency: a rare, treatable cause of complicated hereditary spastic paraplegia.
Spastic Paraplegia, Hereditary
Severe methylenetetrahydrofolate reductase deficiency: clinical clues to a potentially treatable cause of adult-onset hereditary spastic paraplegia.
Spina Bifida Occulta
677C>T and 1298A>C polymorphisms of methylenetetrahydropholate reductase gene and biochemical parameters in Turkish population with spina bifida occulta.
Spinal Cord Diseases
Methylenetetrahydrofolate Reductase Deficiency as a Cause of Treatable Adult-onset Leukoencephalopathy and Myelopathy.
Spinal Cord Diseases
MTHFR C677T polymorphism is associated with methotrexate-induced myelopathy risk.
Spinal Cord Diseases
Reversible nitrous oxide myelopathy and a polymorphism in the gene encoding 5,10-methylenetetrahydrofolate reductase.
Spinal Dysraphism
118 SNPs of folate-related genes and risks of spina bifida and conotruncal heart defects.
Spinal Dysraphism
5,10 Methylenetetrahydrofolate reductase genetic polymorphism as a risk factor for neural tube defects.
Spinal Dysraphism
Altered folate metabolism and disposition in mothers affected by a spina bifida pregnancy: influence of 677c --> t methylenetetrahydrofolate reductase and 2756a --> g methionine synthase genotypes.
Spinal Dysraphism
Association of Fetal MTHFR C677T Polymorphism with Susceptibility to Neural Tube Defects: A Systematic Review and Update Meta-Analysis.
Spinal Dysraphism
Association of neural tube defects in children of mothers with MTHFR 677TT genotype and abnormal carbohydrate metabolism risk: a case-control study.
Spinal Dysraphism
C677T mutation in methylenetetrahydrofolate reductase gene and neural tube defects: should Japanese women undergo gene screening before pregnancy?
Spinal Dysraphism
Distribution of alleles of the methylenetetrahydrofolate reductase (MTHFR) C677T gene polymorphism in familial spina bifida.
Spinal Dysraphism
Elevated plasma total homocysteine and C677T mutation of the methylenetetrahydrofolate reductase gene in patients with spina bifida.
Spinal Dysraphism
Evaluation of 64 candidate single nucleotide polymorphisms as risk factors for neural tube defects in a large Irish study population.
Spinal Dysraphism
Evaluation of infant methylenetetrahydrofolate reductase genotype, maternal vitamin use, and risk of high versus low level spina bifida defects.
Spinal Dysraphism
Evaluation of the MTHFR C677T allele and the MTHFR gene locus in a German spina bifida population.
Spinal Dysraphism
Genetic and biochemical determinants of serum concentrations of monocyte chemoattractant protein-1, a potential neural tube defect risk factor.
Spinal Dysraphism
Genetic association analyses of nitric oxide synthase genes and neural tube defects vary by phenotype.
Spinal Dysraphism
Genetic variation associated with the occurrence and progression of neurological disorders.
Spinal Dysraphism
Genomic structure and transcript variants of the human methylenetetrahydrofolate reductase gene.
Spinal Dysraphism
Maternal vitamin use, genetic variation of infant methylenetetrahydrofolate reductase, and risk for spina bifida.
Spinal Dysraphism
Methylenetetrahydrofolate reductase (MTHFR): incidence of mutations C677T and A1298C in Brazilian population and its correlation with plasma homocysteine levels in spina bifida.
Spinal Dysraphism
Methylenetetrahydrofolate reductase (MTHFR): the incidence of mutations C677T and A1298C in the Ashkenazi Jewish population.
Spinal Dysraphism
Methylenetetrahydrofolate reductase and spina bifida: evaluation of level of defect and maternal genotypic risk in Hispanics.
Spinal Dysraphism
Molecular genetic analysis of the gene encoding the trifunctional enzyme MTHFD (methylenetetrahydrofolate-dehydrogenase, methenyltetrahydrofolate-cyclohydrolase, formyltetrahydrofolate synthetase) in patients with neural tube defects.
Spinal Dysraphism
Mutated methylenetetrahydrofolate reductase as a risk factor for spina bifida.
Spinal Dysraphism
Spina bifida, folate metabolism, and dietary folate intake in a Northern Canadian aboriginal population.
Spinal Dysraphism
The 894G>T variant in the endothelial nitric oxide synthase gene and spina bifida risk.
Spinal Dysraphism
The C677T mutation of the 5,10-methylenetetrahydrofolate reductase gene is a moderate risk factor for spina bifida in Italy.
Spinal Dysraphism
Transcobalamin and methionine synthase reductase mutated polymorphisms aggravate the risk of neural tube defects in humans.
Spinal Dysraphism
[Frequency of C677T polymorphism of 5, 10-methylenetetrahydrofolate reductase (MTHFR) in Chilean mothers of spina bifida cases and controls ]
Spinal Dysraphism
[Vascular diseases, spina bifida and schizophrenia in a single family associated with the heterozygote mutation of the heat-sensitive variant of methylenetetrahydrofolate reductase]
Spinocerebellar Ataxias
One?carbon metabolism factor MTHFR variant is associated with saccade latency in Spinocerebellar Ataxia type 2.
Splenic Infarction
Acute complete splenic infarction in a patient with Hirschsprung's disease and literature review of complete splenic infarction.
Spondylitis, Ankylosing
Atherosclerosis in male patients with ankylosing spondylitis: the relation with methylenetetrahydrofolate reductase (C677T) gene polymorphism and plasma homocysteine levels.
Spondylitis, Ankylosing
The effect of IL-4 and MTHFR gene variants in ankylosing spondylitis.
Squamous Cell Carcinoma of Head and Neck
Association between 11 genetic polymorphisms in folate-metabolising genes and head and neck cancer risk.
Squamous Cell Carcinoma of Head and Neck
Association between dietary folate intake and clinical outcome in head and neck squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Dietary folate is associated with p16(INK4A) methylation in head and neck squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Methylenetetrahydrofolate reductase C677T and A1298C gene polymorphisms in oral squamous cell carcinoma in south-east Iran.
Squamous Cell Carcinoma of Head and Neck
MTHFR C677T and A1298C polymorphisms as predictors of radiotherapy response in head and neck squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
One-carbon metabolism-related gene polymorphisms and risk of head and neck squamous cell carcinoma: case-control study.
Squamous Cell Carcinoma of Head and Neck
Polymorphism in ADH and MTHFR genes in oral squamous cell carcinoma of Indians.
Squamous Cell Carcinoma of Head and Neck
Polymorphism of methylenetetrahydrofolate reductase (MTHFR) gene and risk of head and neck squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Polymorphisms and haplotypes in methylenetetrahydrofolate reductase gene and head and neck squamous cell carcinoma risk.
Squamous Cell Carcinoma of Head and Neck
The association between MTHFR gene polymorphisms (C677T, A1298C) and oral squamous cell carcinoma: A systematic review and meta-analysis.
Squamous Cell Carcinoma of Head and Neck
[Association between genetic polymorphisms in methylenetetrahydrofolate reductase and risk of laryngeal squamous cell carcinoma]
ST Elevation Myocardial Infarction
C677T polymorphism of the 5,10 MTHFR gene in young Mexican subjects with ST-elevation myocardial infarction.
ST Elevation Myocardial Infarction
Characteristics and Long-Term Prognosis of Patients ?35 Years of Age with ST Segment Elevation Myocardial Infarction and "Normal or Near Normal" Coronary Arteries.
ST Elevation Myocardial Infarction
Homozygosity of the TT methylenetetrahydrofolate reductase C677T genotype is an independent long-term predictor of cardiac death in patients with premature myocardial infarction.
ST Elevation Myocardial Infarction
Multiple gene polymorphisms predisposing to the prothrombotic state in an adolescent with acute myocardial infarction.
ST Elevation Myocardial Infarction
The Association of Hereditary Prothrombotic Risk Factors with ST-Elevation Myocardial Infarction.
Stillbirth
Factor V Leiden, pregnancy complications and adverse outcomes: the Hordaland Homocysteine Study.
Stomach Neoplasms
A Functional Variant at the miR-214 Binding Site in the Methylenetetrahydrofolatereductase Gene Alters Susceptibility to Gastric Cancer in a Chinese Han Population.
Stomach Neoplasms
A Meta-Analysis: Methylenetetrahydrofolate Reductase C677T Polymorphism in Gastric Cancer Patients Treated with 5-Fu Based Chemotherapy Predicts Serious Hematologic Toxicity but Not Prognosis.
Stomach Neoplasms
A retrospective comparative exploratory study on two Methylentetrahydrofolate Reductase (MTHFR) polymorphisms in esophagogastric cancer: the A1298C MTHFR polymorphism is an independent prognostic factor only in neoadjuvantly treated gastric cancer patients.
Stomach Neoplasms
A systematic review of meta-analyses on gene polymorphisms and gastric cancer risk.
Stomach Neoplasms
Aberrant DNA Methylation of P16, MGMT, and hMLH1 Genes in Combination with MTHFR C677T Genetic Polymorphism in gastric cancer.
Stomach Neoplasms
Aberrant DNA Methylation of P16, MGMT, hMLH1 and hMSH2 Genes in Combination with the MTHFR C677T Genetic Polymorphism in Gastric Cancer.
Stomach Neoplasms
Aberrant DNA methylation of the P16, MGMT, and hMLH1 genes in combination with the methylenetetrahydrofolate reductase C677T genetic polymorphism and folate intake in gastric cancer.
Stomach Neoplasms
Association between the MTHFR C677T polymorphism and gastric cancer susceptibility: A meta-analysis of 5,757 cases and 8,501 controls.
Stomach Neoplasms
Association between the MTHFR C677T polymorphism and risk of cancer: evidence from 446 case-control studies.
Stomach Neoplasms
Association of methylenetetrahydrofolate reductase (MTHFR) polymorphisms with genetic susceptibility to gastric cancer: a meta-analysis.
Stomach Neoplasms
Association of MTHFR C677T polymorphism with severity and localization of chronic atrophic gastritis patients without Helicobacter pylori infection: a case control study.
Stomach Neoplasms
Association of the methylenetetrahydrofolate reductase polymorphism in Korean patients with childhood acute lymphoblastic leukemia.
Stomach Neoplasms
Association Study between Folate Pathway Gene Single Nucleotide Polymorphisms and Gastric Cancer in Koreans.
Stomach Neoplasms
Associations of the MTHFR rs1801133 polymorphism with gastric cancer risk in the Chinese Han population.
Stomach Neoplasms
Decrease in gastric cancer susceptibility by MTHFR C677T polymorphism in Ardabil Province, Iran.
Stomach Neoplasms
Diet folate, DNA methylation and polymorphisms in methylenetetrahydrofolate reductase in association with the susceptibility to gastric cancer.
Stomach Neoplasms
Dietary folate and vitamin B12 intake before diagnosis decreases gastric cancer mortality risk among susceptible MTHFR 677TT carriers.
Stomach Neoplasms
Dietary folate, one-carbon metabolism-related genes, and gastric cancer risk in Korea.
Stomach Neoplasms
DNA Repair Gene and MTHFR Gene Polymorphisms as Prognostic Markers in Locally Advanced Adenocarcinoma of the Esophagus or Stomach Treated with Cisplatin and 5-Fluorouracil-Based Neoadjuvant Chemotherapy.
Stomach Neoplasms
Evaluation of an Association of Blood Homocysteine Levels With Gastric Cancer Risk From 27 Case-Control Studies.
Stomach Neoplasms
Folate intake along with genetic polymorphisms in methylenetetrahydrofolate reductase and thymidylate synthase in patients with advanced gastric cancer.
Stomach Neoplasms
Folate intake, MTHFR polymorphisms, and risk of esophageal, gastric, and pancreatic cancer: a meta-analysis.
Stomach Neoplasms
Folate levels in mucosal tissue but not methylenetetrahydrofolate reductase polymorphisms are associated with gastric carcinogenesis.
Stomach Neoplasms
Gastric cancer in relation to the intake of nutrients involved in one-carbon metabolism among MTHFR 677 TT carriers.
Stomach Neoplasms
Genetic polymorphisms in folate metabolism and the risk of stomach cancer.
Stomach Neoplasms
Genetic polymorphisms in folate-metabolizing genes associated with gastric cancer prognosis in northwest China subjects.
Stomach Neoplasms
Genetic susceptibility to cancer: the role of polymorphisms in candidate genes.
Stomach Neoplasms
Hyperhomocysteinemia, methylenetetrahydrofolate reductase c.677C>T polymorphism, and risk of cancer: cross-sectional and prospective studies and meta-analyses of 75,000 cases and 93,000 controls.
Stomach Neoplasms
Impact of methylenetetrahydrofolate reductase C677T polymorphism on the risk of gastric cancer and its interaction with Helicobacter pylori infection.
Stomach Neoplasms
Impact of methylenetetrahydrofolate reductase polymorphisms and folate intake on the risk of gastric cancer and their association with Helicobacter pylori infection and tumor site.
Stomach Neoplasms
Impacts of excision repair cross-complementing gene 1 (ERCC1), dihydropyrimidine dehydrogenase, and epidermal growth factor receptor on the outcomes of patients with advanced gastric cancer.
Stomach Neoplasms
Influences of ERCC1, ERCC2, XRCC1, GSTP1, GSTT1, and MTHFR polymorphisms on clinical outcomes in gastric cancer patients treated with EOF chemotherapy.
Stomach Neoplasms
Involvement of genetic factors and lifestyle on the occurrence of colorectal and gastric cancer.
Stomach Neoplasms
Knock-down of methylenetetrahydrofolate reductase reduces gastric cancer cell survival: an in vitro study.
Stomach Neoplasms
Meta- and pooled analyses of the methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and gastric cancer risk: a huge-GSEC review.
Stomach Neoplasms
Methylenetetrahydrofolate reductase 677C/T gene polymorphism, gastric cancer susceptibility and genomic DNA hypomethylation in an at-risk Italian population.
Stomach Neoplasms
Methylenetetrahydrofolate reductase 677C>T polymorphism and gastric cancer susceptibility in Mexico.
Stomach Neoplasms
Methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and gastric cancer susceptibility.
Stomach Neoplasms
Methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and gastric cancer: a meta-analysis.
Stomach Neoplasms
Methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and susceptibility to gastric adenocarcinoma in an Italian population.
Stomach Neoplasms
Methylenetetrahydrofolate reductase C677T polymorphism in patients with gastric and colorectal cancer in a Korean population.
Stomach Neoplasms
Methylenetetrahydrofolate reductase C677T polymorphism in patients with gastric and colorectal cancer.
Stomach Neoplasms
Methylenetetrahydrofolate reductase gene polymorphisms and lung cancer: a meta-analysis.
Stomach Neoplasms
Methylenetetrahydrofolate reductase polymorphisms and susceptibility to gastric cancer in Chinese populations: a meta-analysis.
Stomach Neoplasms
Methylenetetrahydrofolate reductase polymorphisms/haplotypes and risk of gastric cancer: a case-control analysis in China.
Stomach Neoplasms
MiR-22, regulated by MeCP2, suppresses gastric cancer cell proliferation by inducing a deficiency in endogenous S-adenosylmethionine.
Stomach Neoplasms
MTHFR C677T and A1298C Polymorphisms in Breast Cancer, Gliomas and Gastric Cancer: A Review.
Stomach Neoplasms
MTHFR C677T polymorphism and differential methylation status in gastric cancer: an association with Helicobacter pylori infection.
Stomach Neoplasms
MTHFR C677T polymorphisms and childhood acute lymphoblastic leukemia: A meta-analysis.
Stomach Neoplasms
MTHFR polymorphisms in gastric cancer and in first-degree relatives of patients with gastric cancer.
Stomach Neoplasms
MTHFR polymorphisms involved in vitamin B12 deficiency associated with atrophic gastritis.
Stomach Neoplasms
Polymorphism of methylenetetrahydrofolate reductase gene is associated with response to fluorouracil-based chemotherapy in Chinese patients with gastric cancer.
Stomach Neoplasms
Polymorphism of TS 3'-UTR predicts survival of Chinese advanced gastric cancer patients receiving first-line capecitabine plus paclitaxel.
Stomach Neoplasms
Polymorphisms in ERCC1, GSTs, TS and MTHFR predict clinical outcomes of gastric cancer patients treated with platinum/5-Fu-based chemotherapy: a systematic review.
Stomach Neoplasms
Polymorphisms in thymidylate synthase and methylenetetrahydrofolate reductase genes and the susceptibility to esophageal and stomach cancer with smoking.
Stomach Neoplasms
Polymorphisms of 5,10-methylenetetrahydrofolate reductase and risk of stomach cancer in a Korean population.
Stomach Neoplasms
Polymorphisms of 5,10-methylenetetralydrofolate reductase (MTHFR), fruit and vegetable intake, and the risk of stomach cancer.
Stomach Neoplasms
Polymorphisms of MTHFD, plasma homocysteine levels, and risk of gastric cancer in a high-risk Chinese population.
Stomach Neoplasms
Single nucleotide polymorphisms of one-carbon metabolism and cancers of the esophagus, stomach, and liver in a Chinese population.
Stomach Neoplasms
The association of gastric cancer risk with plasma folate, cobalamin, and methylenetetrahydrofolate reductase polymorphisms in the European Prospective Investigation into Cancer and Nutrition.
Stomach Neoplasms
The methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and tumor risk: evidence from 134 case-control studies.
Stomach Neoplasms
The polymorphism of methylenetetrahydrofolate reductase C677T but not A1298C contributes to gastric cancer.
Stomach Neoplasms
The polymorphisms of TS and MTHFR predict survival of gastric cancer patients treated with fluorouracil-based adjuvant chemotherapy in Chinese population.
Stomach Neoplasms
Thymidylate synthase and methylenetetrahy-drofolate reductase gene polymorphisms and gastric cancer susceptibility in a population of Northern Brazil.
Stomach Neoplasms
Vitamins B2 and B6 and genetic polymorphisms related to one-carbon metabolism as risk factors for gastric adenocarcinoma in the European prospective investigation into cancer and nutrition.
Stomach Neoplasms
[C677T polymorphism of the MTHFR gene and the risk of developing distal gastric cancer in a Mexican population]
Stomach Neoplasms
[Clinical significance of thymidylate synthase and methylenetetrahydrofolate reductase gene polymorphism in Korean patients with gastric cancer]
Stomach Neoplasms
[Polymorphism of methylenetetrahydrofolate reductase and sensitivity of stomach cancer to fluoropyrimidine-based chemotherapy]
Stomach Neoplasms
[Polymorphisms of methylenetetrahydrofolate reductase C677T and the risk of stomach cancer]
Stomach Neoplasms
[The relationship between methylenetetrahydrofolate reductase gene polymorphism and microsatellite instability in gastric cancer]
Stomatitis
Methotrexate-induced toxicity pharmacogenetics: an umbrella review of systematic reviews and meta-analyses.
Stomatitis
Methylenetetrahydrofolate reductase and thymidylate synthase genotypes modify oral mucositis severity following hematopoietic stem cell transplantation.
Stomatitis
PACSIN2 polymorphism is associated with thiopurine-induced hematological toxicity in children with acute lymphoblastic leukaemia undergoing maintenance therapy.
Stomatitis
Predictors of oral mucositis in patients receiving hematopoietic cell transplants for chronic myelogenous leukemia.
Stomatitis, Aphthous
Association of MTHFR gene C677T mutation with recurrent aphthous stomatitis and number of oral ulcers.
Stroke
A child with Diamond-Blackfan anemia, methylenetetrahydrofolate reductase mutation, and perinatal stroke.
Stroke
A common polymorphism in the methylenetetrahydrofolate reductase gene, homocysteine, and ischemic cerebrovascular disease.
Stroke
A genetic deficiency in folic acid metabolism impairs recovery after ischemic stroke.
Stroke
A magnetic nanoparticles-based method for DNA extraction from the saliva of stroke patients.
Stroke
A meta-analysis of the relationship between MTHFR gene A1298C polymorphism and the risk of adult stroke.
Stroke
A novel multiplex PCR-RFLP method for simultaneous detection of the MTHFR 677 C > T, eNOS +894 G > T and - eNOS -786 T > C variants among Malaysian Malays.
Stroke
A prospective cohort study of MTHFR C677T gene polymorphism and its influence on the therapeutic effect of homocysteine in stroke patients with hyperhomocysteinemia.
Stroke
Acute stroke in relation to homocysteine and methylenetetrahydrofolate reductase gene polymorphisms.
Stroke
Addressing optimal folate and related B-vitamin status through the lifecycle: health impacts and challenges.
Stroke
Analysis of genetic polymorphisms related to thrombosis and other risk factors in patients with retinal vein occlusion.
Stroke
Anesthesia for cesarean section in a patient with placenta previa and methylenetetrahydrofolate reductase deficiency.
Stroke
Association between 5,10-Methylenetetrahydrofolate Reductase C677T Gene Polymorphism and Risk of Ischemic Stroke: A Meta-analysis.
Stroke
Association between methylene tetrahydrofolate reductase polymorphisms and risk of ischemic stroke.
Stroke
Association of gene polymorphism with genetic susceptibility to stroke in Asian populations: a meta-analysis.
Stroke
Association of Homocysteine with Aysmptomatic Intracranial and Extracranial Arterial Stenosis in Hypertension Patients.
Stroke
Association of methylenetetrahydrofolate reductase gene C677T polymorphism with polycystic ovary syndrome risk: a systematic review and meta-analysis update.
Stroke
Association of MTHFR C677T Genotype With Ischemic Stroke Is Confined to Cerebral Small Vessel Disease Subtype.
Stroke
Association of the APOE, MTHFR and ACE Genes Polymorphisms and Stroke in Zambian Patients.
Stroke
Association of the methylenetetrahydrofolate reductase gene A1298C polymorphism with stroke risk based on a meta-analysis.
Stroke
Associations between 2 polymorphisms in the methylenetetrahydrofolate reductase gene and placental abruption.
Stroke
B-vitamin and choline supplementation increases neuroplasticity and recovery after stroke.
Stroke
C677T MTHFR mutation and factor V Leiden mutation in patients with TIA/minor stroke: a case-control study.
Stroke
C677T polymorphism of the methylenetetrahydrofolate reductase gene and the risk of ischemic stroke in Polish subjects.
Stroke
Case-control Study of methylenetetrahydrofolate reductase mutations and hyperhomocysteinemia and risk of stroke.
Stroke
Causal relationship of susceptibility genes to ischemic stroke: comparison to ischemic heart disease and biochemical determinants.
Stroke
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) in a Greek family.
Stroke
Children with stroke: polymorphism of the MTHFR gene, mild hyperhomocysteinemia, and vitamin status.
Stroke
Clinical presentation, etiology, and outcome of stroke in children: A hospital-based study.
Stroke
Coexistence of Neurofibromatosis Type-1 and MTHFR C677T Gene Mutation in a Young Stroke Patient: A Case Report.
Stroke
Common genetic variants of homocysteine metabolism in ischemic stroke: a case-control study.
Stroke
Congenital MTHFR deficiency causing early-onset cerebral stroke in a case homozygous for MTHFR thermolabile variant.
Stroke
Connection between small vessel disease related stroke and the MTHFR C677T polymorphism in a Hungarian population.
Stroke
Correlation of polymorphisms to coagulation and biochemical risk factors for cardiovascular diseases.
Stroke
Correlation of the C677T MTHFR genotype with homocysteine levels in children with sickle cell disease.
Stroke
Cumulative effect of predisposing genotypes and their interaction with modifiable factors on the risk of ischemic stroke in young adults.
Stroke
Detailed analysis of gene polymorphisms associated with ischemic stroke in South asians.
Stroke
Dose-related association of MTHFR 677T allele with risk of ischemic stroke: evidence from a cumulative meta-analysis.
Stroke
Effect modification by population dietary folate on the association between MTHFR genotype, homocysteine, and stroke risk: a meta-analysis of genetic studies and randomised trials.
Stroke
Effect of folic acid supplementation on cancer risk among adults with hypertension in China: A randomized clinical trial.
Stroke
Effect of gene-gene and gene-environment interaction on the risk of first-ever stroke and poststroke death.
Stroke
Elevated plasma homocysteine was associated with hemorrhagic and ischemic stroke, but methylenetetrahydrofolate reductase gene C677T polymorphism was a risk factor for thrombotic stroke: a Multicenter Case-Control Study in China.
Stroke
Factor V Leiden and antiphospholipid antibodies are significant risk factors for ischemic stroke in children.
Stroke
Factor V Leiden, prothrombin 20210G-->A and the MTHFR C677T mutations in childhood stroke.
Stroke
Folate, vitamin B12, and risk of ischemic and hemorrhagic stroke: a prospective, nested case-referent study of plasma concentrations and dietary intake.
Stroke
Genetic analysis of the thermolabile variant of 5, 10-methylenetetrahydrofolate reductase as a risk factor for ischemic stroke.
Stroke
Genetic and nongenetic factors influencing plasma homocysteine levels in patients with ischemic cerebrovascular disease and in healthy control subjects.
Stroke
Genetic polymorphisms of Chinese patients with ischemic stroke and concurrent stenoses of extracranial and intracranial vessels.
Stroke
Genetic Risk Factors for Arterial Ischemic Stroke in Children: A Possible MTHFR and eNOS Gene-Gene Interplay?
Stroke
Heterogeneity of Association Between MTHFR and Stroke Among European Regions: Additional Population Studies Are Needed in Italy.
Stroke
High plasma homocysteine levels contribute to the risk of stroke recurrence and all-cause mortality in a large prospective stroke population.
Stroke
Homocysteine and Stroke Risk: Modifying Effect of Methylenetetrahydrofolate Reductase C677T Polymorphism and Folic Acid Intervention.
Stroke
Homocysteine, small-vessel disease, and atherosclerosis: an MRI study of 825 stroke patients.
Stroke
Homocystine levels, polymorphisms and the risk of ischemic stroke in young Asian Indians.
Stroke
Homozygous thermolabile variant of the methylenetetrahydrofolate reductase gene: a potential risk factor for hyperhomocysteinaemia, CVD, and stroke in childhood.
Stroke
Homozygous VN (677C to T) and d/D (2756G to A) variants in the methylenetetrahydrofolate and methionine synthase genes in a case of hyperhomocysteinemia with stroke at young age.
Stroke
Identification of genetic contribution to ischemic stroke by screening of single nucleotide polymorphisms in stroke patients by using a case control study design (Study protocol).
Stroke
Inherited DNA mutations contributing to thrombotic complications in patients with sickle cell disease.
Stroke
Inherited prothrombotic risk factors in children with stroke, transient ischemic attack, or migraine.
Stroke
Inherited thrombophilia and stratification of ischaemic stroke risk among users of oral contraceptives.
Stroke
Interaction between methylenetetrahydrofolate reductase C677T gene polymorphism and sleep duration on risk of stroke pathogenesis.
Stroke
Interaction of genetic risk factors confers higher risk for thrombotic stroke in male Chinese: a multicenter case-control study.
Stroke
Interaction of homocysteine and conventional predisposing factors on risk of ischaemic stroke in young people: consistency in phenotype-disease analysis and genotype-disease analysis.
Stroke
Interplay between 3'-UTR polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene and the risk of ischemic stroke.
Stroke
Lipoprotein (a) and genetic polymorphisms of clotting factor V, prothrombin, and methylenetetrahydrofolate reductase are risk factors of spontaneous ischemic stroke in childhood.
Stroke
Malignant stroke in an adolescent with a homozygous MTHFR 677CT mutation and intake of hormonal contraceptives.
Stroke
MAT1A variants are associated with hypertension, stroke, and markers of DNA damage and are modulated by plasma vitamin B-6 and folate.
Stroke
Methylenetetrahydrofolate reductase C677T polymorphism, hypertension and risk of stroke: a prospective, nested case-control study.
Stroke
Methylenetetrahydrofolate reductase gene polymorphisms are associated with ischemic and hemorrhagic stroke: Dual effect of MTHFR polymorphisms C677T and A1298C.
Stroke
Methylenetetrahydrofolate reductase polymorphisms and homocysteine-lowering effect of vitamin therapy in Singaporean stroke patients.
Stroke
Methylentetrahydrofolate Reductase and Nitric Oxide Synthase Polymorphism in Patients with Atherosclerosis and Diabetes.
Stroke
Microarray analysis of brain RNA in mice with methylenetetrahydrofolate reductase deficiency and hyperhomocysteinemia.
Stroke
Migraine mediates the influence of C677T MTHFR genotypes on ischemic stroke risk with a stroke-subtype effect.
Stroke
Moderately elevated plasma homocysteine, methylenetetrahydrofolate reductase genotype, and risk for stroke, vascular dementia, and Alzheimer disease in Northern Ireland.
Stroke
MTHFR 677 TT genotype and hyperhomocysteinaemia: an underestimated risk TANDEM for patients with stroke.
Stroke
MTHFR C677T gene mutation as a risk factor for arterial stroke: a hospital based study.
Stroke
MTHFR C677T polymorphism and its relation to ischemic stroke in the Black Sea Turkish population.
Stroke
MTHFR C677T Polymorphism as a Risk Factor for Vascular Calcification in Chronic Hemodialysis Patients.
Stroke
MTHFR gene polymorphism as a risk factor for silent brain infarcts and white matter lesions in the Japanese general population: The NILS-LSA Study.
Stroke
Neonatal stroke associated with de novo antiphospholipid antibody and homozygous 1298C/C methylenetetrahydrofolate reductase mutation.
Stroke
Pediatric stroke and methylenetetrahydrofolate reductase polymorphisms: an examination of C677T and A1298C mutations.
Stroke
Plasma homocysteine concentration, C677T MTHFR genotype, and 844ins68bp CBS genotype in young adults with spontaneous cervical artery dissection and atherothrombotic stroke.
Stroke
Polymorphism of apoprotein E (APOE), methylenetetrahydrofolate reductase (MTHFR) and paraoxonase (PON1) genes in patients with cerebrovascular disease.
Stroke
Posterior cerebral artery occlusion after Mycoplasma pneumoniae infection associated with genetic defect of MTHFR C677T.
Stroke
Prospective study of first stroke in relation to plasma homocysteine and MTHFR 677C>T and 1298A>C genotypes and haplotypes - evidence for an association with hemorrhagic stroke.
Stroke
Prothrombotic Genetic Risk Factors in Stroke : A Possible Different Role in Pediatric and Adult Patients.
Stroke
Prothrombotic polymorphisms, mutations, and their association with pediatric non-cardioembolic stroke in Asian-Indian patients.
Stroke
Quantitative assessment of association between rs1801133 polymorphism and susceptibility to stroke.
Stroke
Red cell N5-methyltetrahydrofolate concentrations and C677T methylenetetrahydrofolate reductase genotype in patients with stroke.
Stroke
Relationship between methylenetetrahydrofolate reductase (MTHFR) gene (A1298C) polymorphism with the risk of stroke: A systematic review and meta-analysis.
Stroke
Relationship of MTHFR Gene 677C?T Polymorphism, Homocysteine, and Estimated Glomerular Filtration Rate Levels With the Risk of New-Onset Diabetes.
Stroke
Role of a common mutation in the homocysteine regulatory enzyme methylenetetrahydrofolate reductase in ischemic stroke.
Stroke
Role of Methylenetetrahydrofolate Reductase Gene (MTHFR) 677C>T Polymorphism in Pediatric Cerebrovascular Disorders.
Stroke
ST-elevation myocardial infarction, pulmonary embolism, and cerebral ischemic stroke in a patient with critically low levels of natural anticoagulants.
Stroke
Stroke in Young Military Men With Heterozygous for MTHFR Gene Mutation or Factor V Leiden Gene Mutation Associated With Patent Foramen Ovale: Report of Two Cases and Therapeutic Strategy.
Stroke
Symptomatic ischemic stroke in full-term neonates : role of acquired and genetic prothrombotic risk factors.
Stroke
The Connotation of Variances in the Risk Predictors, Medications, Homocysteine, and Homocysteine Pathway Gene Polymorphisms with CVA/Stroke.
Stroke
The Methylenetetrahydrofolate Reductase C677T (rs1801133) and Apolipoprotein A5-1131T>C (rs662799) Polymorphisms, and Anemia Are Independent Risk Factors for Ischemic Stroke.
Stroke
The methylenetetrahydrofolate reductase gene C677T polymorphism in patients with homozygous sickle cell disease and stroke.
Stroke
The model homologue of the partially defective human 5,10-methylenetetrahydrofolate reductase, considered as a risk factor for stroke due to increased homocysteine level, can be protected and reactivated by heat shock proteins.
Stroke
The modifying effect of the MTHFR genotype on the association between folic acid supplementation and pulse wave velocity: Findings from the CSPPT.
Stroke
The MTHFR CT polymorphism confers a high risk for stroke in both homozygous and heterozygous T allele carriers with Type 2 diabetes.
Stroke
The role of classic risk factors and prothrombotic factor gene mutations in ischemic stroke risk development in young and middle-aged individuals.
Stroke
The T allele of the 677C>T polymorphism of methylenetetrahydrofolate reductase gene is associated with an increased risk of ischemic stroke in Polish children.
Stroke
The TT genotype of methylenetetrahydrofolate reductase 677C>T polymorphism increases the susceptibility to pediatric ischemic stroke: meta-analysis of the 822 cases and 1,552 controls.
Stroke
The U-shaped relationship between serum methylene tetrahydrofolate reductase and large-artery atherosclerotic stroke.
Stroke
Thrombophilic predisposition in stroke and venous thromboembolism in Danish patients.
Stroke
Zinc Finger 259 Gene Polymorphism rs964184 is Associated with Serum Triglyceride Levels and Metabolic Syndrome.
Stroke
[A case-control study on the relationship between stroke and plasma homocysteine level and the mutation of MTHFR gene.]
Stroke
[A comparative analysis of allele frequencies of rs1801133 and rs1801131 of MTHFR in patients with stroke and healthy people from the Moscow region].
Stroke
[Association study of renin-angiotensin system genes and hemostasis system genes with ischemic stroke among Russians of Central Russia].
Stroke
[Hereditary thrombophilia with ischemiC stroke and sinus thrombosis. Diagnosis, therapy and meta-analysis]
Stroke
[Hyperhomocysteine, methylenetetrahydrofolate reductase gene, and other risk factors in ischemic stroke]
Stroke, Lacunar
Association of MTHFR C677T Genotype With Ischemic Stroke Is Confined to Cerebral Small Vessel Disease Subtype.
Subacute Combined Degeneration
Methylenetetrahydrofolate Reductase (MTHFR) C677T Polymorphism and Subacute Combined Degeneration: Revealing a Genetic Predisposition.
Subarachnoid Hemorrhage
Methylenetetrahydrofolate reductase C677T variant and hyperhomocysteinemia in subarachnoid hemorrhage patients from India.
Syncope
Massive pulmonary embolism in a Lebanese patient doubly heterozygous for MTHFR and Factor V Leiden presenting with syncope and treated with tenecteplase.
t-plasminogen activator deficiency
Recurrent miscarriage syndrome and infertility due to blood coagulation protein/platelet defects: a review and update.
Tachycardia
Ischemic Stroke in a Patient With Atrial Tachycardia, Methylenetetrahydrofolate Reductase Mutation and New-Onset Atrial Fibrillation: Is Early Initiation of Anticoagulation Therapy Indicated?
Takayasu Arteritis
Takayasu arteritis with high titre of antiphospholipid antibodies and MTHFR Polymorphism.
Temporomandibular Joint Disorders
Association of Functional Polymorphisms in Matrix Metalloproteinase-9 and Glutathione S-Transferase T1 Genes with Temporomandibular Disorders.
Tension-Type Headache
The homozygous C677T mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for migraine.
Tetralogy of Fallot
Genomics and Epigenomics of Congenital Heart Defects: Expert Review and Lessons Learned in Africa.
Tetralogy of Fallot
Methylenetetrahydrofolate reductase C677T and reduced folate carrier 80 G>A polymorphisms are associated with an increased risk of conotruncal heart defects.
Tetralogy of Fallot
MTHFR rs1801133 C>T polymorphism is associated with an increased risk of tetralogy of Fallot.
Tetralogy of Fallot
The methylenetetrahydrofolate reductase gene variant (C677T) as a susceptibility gene for tetralogy of Fallot.
Thrombasthenia
Glanzmann Thrombasthenia in a Newborn with Heterozygous Factor V Leiden and Heterozygous MTHFR C677T Gene Mutations.
Thromboangiitis Obliterans
A case of Buerger's disease associated with MTHFR C677T mutation homozygosity: a possible therapeutic support.
Thromboangiitis Obliterans
Stromelysin-1 5A/6A and eNOS T-786C Polymorphisms, MTHFR C677T and A1298C Mutations, and Cigarette-Cannabis Smoking: A Pilot, Hypothesis-Generating Study of Gene-Environment Pathophysiological Associations With Buerger's Disease.
Thrombocythemia, Essential
The relationship between factor V Leiden, prothrombin G20210A, and MTHFR mutations and the first major thrombotic episode in polycythemia vera and essential thrombocythemia.
Thrombocythemia, Essential
Thrombophilic Risk of Factor V Leiden, Prothrombin G20210A, MTHFR, and Calreticulin Mutations in Essential Thrombocythemia Egyptian Patients.
Thrombocytopenia
A newborn case with perinatal-lethal Gaucher disease due to R463H homozygosity complicated by C677T homozygosity in the MTHFR gene.
Thrombocytopenia
Association of C677T and A1298C MTHFR Polymorphisms and Fluoropyrimidine-induced Toxicity in Mestizo Patients With Metastatic Colorectal Cancer.
Thrombocytopenia
Complete deficiency of methylenetetrahydrofolate reductase in mice is associated with impaired retinal function and variable mortality, hematological profiles, and reproductive outcomes.
Thrombocytopenia
Gene-Gene Interactions of Gemcitabine Metabolizing-Enzyme Genes hCNT3 and WEE1 for Preventing Severe Gemcitabine-Induced Hematological Toxicity.
Thrombocytopenia
Methylenetetrahydrofolate reductase C677T and A1298C gene polymorphisms and therapy-related toxicity in children treated for acute lymphoblastic leukemia and non-Hodgkin lymphoma.
Thrombocytopenia
Platelet receptor and clotting factor polymorphisms as genetic risk factors for thromboembolic complications in heparin-induced thrombocytopenia.
Thrombocytopenia
Possible roles of methylenetetrahydrofolate reductase polymorphism and folate status in patients with early hepatitis C virus genotype 4.
Thrombocytopenia
Prognostic Genetic Markers for Thrombosis in COVID-19 Patients: A Focused Analysis on D-Dimer, Homocysteine and Thromboembolism.
Thrombocytopenia
[Acute cerebral sinus-thrombosis due to polyangiitis overlap syndrome with granulomatosis with polyangiitis (Wegener's granulomatosis) and eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome)].
Thrombocytosis
Chronic Myeloid Leukemia with b3a3 (e14a3) Fusion: A Rare BCR/ABL Rearrangement Presenting with Thrombocytosis - Does MTHFR Polymorphism Matter.
Thrombocytosis
Statistical Correlations of the Spontaneous Abortion with Trombophilia and Other Associated Pathologies.
Thromboembolism
Arterial thrombosis associated with factor V Leiden and methylenetetrahydrofolate reductase C677T mutation in childhood membranous glomerulonephritis.
Thromboembolism
Case-control study of the frequency of thrombophilic disorders in couples with late foetal loss and no thrombotic antecedent--the Nîmes Obstetricians and Haematologists Study5 (NOHA5).
Thromboembolism
Classical familial homocystinuria in an adult presenting as an isolated lens subluxation.
Thromboembolism
Factor V Leiden, factor V Cambridge, factor II GA20210, and methylenetetrahydrofolate reductase in cerebral venous and sinus thrombosis: A case-control study.
Thromboembolism
Factor V Leiden, prothrombin G20210A and methylenetetrahydrofolate reductase (MTHFR) C677T polymorphisms and the risk of tamoxifen-associated thromboembolism in breast cancer patients.
Thromboembolism
Genetic risk factors in young adults with 'cryptogenic' ischemic cerebrovascular disease.
Thromboembolism
Red blood cell methylfolate and plasma homocysteine as risk factors for venous thromboembolism: a matched case-control study.
Thromboembolism
Role of soluble P-selectin and methylenetetrahydrofolate reductase gene polymorphisms (677C>T) in Egyptian patients with venous thromboembolism.
Thromboembolism
Sequential multiple retinal vein occlusions and transient ischemic attack in MTHFR polymorphism and protein S deficiency.
Thromboembolism
The methylenetetrahydrofolate reductase gene polymorphism (C677T) is associated with increased cardiovascular mortality in Hungary.
Thromboembolism
The Methylenetetrahydrofolate Reductase Polymorphism (MTHFR c.677C>T) and Elevated Plasma Homocysteine Levels in a U.S. Pediatric Population with Incident Thromboembolism.
Thromboembolism
Thermolabile methylenetetrahydrofolate reductase: an inherited risk factor for coronary artery disease.
Thromboembolism
Variant alleles in factor V, prothrombin, plasminogen activator inhibitor-1, methylenetetrahydrofolate reductase and risk of thromboembolism in metastatic colorectal cancer patients treated with first-line chemotherapy plus bevacizumab.
Thromboembolism
[Effect of hyperhomocysteinemia and methylenetetrahydrofolate reductase 677C --> T mutation in venous thromboembolism risk of young adults]
Thromboembolism
[Factor V Leiden, FII G20210A, MTHFR C677T mutations as risk factors for venous thrombosis during pregnancy and puerperium]
Thromboembolism
[Venous thromboembolism in a young patient. Diagnosis: Retinal vein thromboembolism in mutation of the methylenetetrahydrofolate reductase gene]
Thrombophilia
A 17-year-old male with pseudotumor cerebri secondary to performance-enhancing steroids triggering venous thrombosis in the brain.
Thrombophilia
A new PCR-SSP typing method for six single-nucleotide polymorphisms impairing the blood-clotting cascade as well as T-cell stimulation.
Thrombophilia
A review on clotting disorders and retinal hemorrhages: Can they mimic abuse?
Thrombophilia
Absence of factor V Arg306--Thr and low factor V Arg306->Gly mutation prevalence in Thai blood donors.
Thrombophilia
Acute ischemic stroke in a 7-month-old infant, risk factors, and diagnosis peculiarities: A case report.
Thrombophilia
Age and homocysteine plasma levels are risk factors for thrombotic complications after ovarian stimulation.
Thrombophilia
An uncommon clinical condition: chronic thrombosis of the inferior vena cava. A case report and review of literature.
Thrombophilia
Analysis of polymorphisms in genes (AGT, MTHFR, GPIIIa, and GSTP1) associated with hypertension, thrombophilia and oxidative stress in Mestizo and Amerindian populations of México.
Thrombophilia
Antiphospholipid antibodies in neonates with stroke--a unique entity or variant of antiphospholipid syndrome?
Thrombophilia
Association between in vitro fertilization outcomes and inherited thrombophilias: a meta-analysis.
Thrombophilia
Association of homocysteine, vitamin B12, folic acid, and MTHFR C677T in patients with a thrombotic event or recurrent fetal loss.
Thrombophilia
Association of MTHFR gene C677T mutation with recurrent aphthous stomatitis and number of oral ulcers.
Thrombophilia
Associations between Maternal and Fetal Inherited Thrombophilias, Placental Characteristics Associated with Vascular Malperfusion, and Fetal Growth.
Thrombophilia
Clinical Impact of Thrombophilia Screening in Young Adults with Ischemic Stroke.
Thrombophilia
Coagulation Biomarkers in Women with Recurrent Miscarriage and Polycystic Ovarian Syndrome: Systematic Review and Meta-Analysis.
Thrombophilia
Coexistence of the methylenetetrahydrofolate reductase single-nucleotide polymorphism (C677T) in patients with the factor V Leiden or prothrombin G20210A polymorphisms.
Thrombophilia
Combination of thrombophilia markers in acute myocardial infarction of the young.
Thrombophilia
Combined portal, splenic and mesenteric venous thrombosis in inactive ulcerative colitis with heterozygous mutation in MTHFR gene: A rare case of thrombophilia.
Thrombophilia
Common C677T polymorphism in the methylenetetrahydrofolate reductase gene increases the risk for deep vein thrombosis in patients with predisposition of thrombophilia.
Thrombophilia
Common C677T polymorphism of the methylenetetrahydrofolate reductase gene and the risk of venous thromboembolism: meta-analysis of 31 studies.
Thrombophilia
Comparison of thrombophilic gene mutations among patients experiencing recurrent miscarriage and deep vein thrombosis.
Thrombophilia
Complicated Lemierre Syndrome Caused by Streptococcus gordonii and Possible Rickettsial Co-Infection in a Patient with Thrombophilia Predisposition.
Thrombophilia
Correlation with Platelet Parameters and Genetic Markers of Thrombophilia Panel (Factor II g.20210G>A, Factor V Leiden, MTHFR (C677T, A1298C), PAI-1, ?-Fibrinogen, Factor XIIIA (V34L), Glycoprotein IIIa (L33P)) in Ischemic Strokes.
Thrombophilia
Dalteparin and low-dose aspirin in the prevention of adverse obstetric outcomes in women with inherited thrombophilia.
Thrombophilia
Defect of methylenetetrahydrofolate reductase in a patient with ten habitual misscarriages: a case report.
Thrombophilia
Detection of 677CT/1298AC "double variant" chromosomes: implications for interpretation of MTHFR genotyping results.
Thrombophilia
Development of a three-biosensor panel for the visual detection of thrombophilia-associated mutations.
Thrombophilia
Differentiation of antemortem pulmonary thromboembolism and postmortem clot with unenhanced MRI: a case report.
Thrombophilia
Do placental lesions reflect thrombophilia state in women with adverse pregnancy outcome?
Thrombophilia
Duplication of inferior vena cava and coagulation mutations with left-sided iliofemoral venous thrombosis.
Thrombophilia
Efficacy and safety of nadroparin and unfractionated heparin for the treatment of venous thromboembolism during pregnancy and puerperium.
Thrombophilia
Etiology of hypercoagulable state in women with recurrent fetal loss without other causes of miscarriage from Southern Italy: new clinical target for antithrombotic therapy.
Thrombophilia
Evaluation of Factor V Leiden, Prothrombin and Methylenetetrahydrofolate Reductase Gene Mutations in Patients with Severe Pregnancy Complications in Northern Finland.
Thrombophilia
Evaluation of GenoFlow Thrombophilia Array Test Kit in its detection of mutations in Factor V Leiden (G1691A), prothrombin G20210A, MTHFR C677T and A1298C in blood samples from 113 Turkish female patients.
Thrombophilia
Factor V Leiden, Prothrombin and MTHFR Mutation in Patients with Preeclamsia, Intrauterine Growth Restriction and Placental Abruption.
Thrombophilia
Free functional muscle transfer failure and thrombophilic gene mutations as a potential risk factor: a case report.
Thrombophilia
Frequency of triple mutations involving factor v, prothrombin, and methylenetetrahydrofolate reductase genes among patients referred for molecular thrombophilia workup in a tertiary care center in Lebanon.
Thrombophilia
Genetic thrombophilia in patients with VTE in eastern Mediterranean located tertiary care center; is it time to change the algorithm for thrombophilia work up decision making?
Thrombophilia
Glanzmann Thrombasthenia in a Newborn with Heterozygous Factor V Leiden and Heterozygous MTHFR C677T Gene Mutations.
Thrombophilia
Hereditary thrombophilia, anti-beta2 glycoprotein 1 IgM, and anti-annexin V antibodies in recurrent pregnancy loss.
Thrombophilia
Hyperhomocysteinemia increases the risk of venous thrombosis independent of the C677T mutation of the methylenetetrahydrofolate reductase gene in selected Brazilian patients.
Thrombophilia
Impact of Factor V Leiden, prothrombin and methylenetetrahydrofolate reductase gene mutations on infant birth weight in women with recurrent fetal loss and women with successful pregnancies.
Thrombophilia
Impact of inherited thrombophilia on the risk of recurrent venous thromboembolism onset in georgian population.
Thrombophilia
Impact of thrombophilia on risk of arterial ischemic stroke or cerebral sinovenous thrombosis in neonates and children: a systematic review and meta-analysis of observational studies.
Thrombophilia
Implantation of left ventricular assist device complicated by undiagnosed thrombophilia.
Thrombophilia
Inherited and acquired thrombophilias and poor pregnancy outcome: should we be treating with heparin?
Thrombophilia
Inherited risk factors for thrombophilia among children with Legg-Calvé-Perthes disease.
Thrombophilia
Inherited thrombophilia and anticoagulant therapy for women with reproductive failure.
Thrombophilia
Inherited thrombophilia and preeclampsia within a multicenter cohort: the Montreal Preeclampsia Study.
Thrombophilia
Inherited thrombophilia as a risk factor for the development of ischemic stroke in young adults.
Thrombophilia
Inherited thrombophilia in infertile women-implication in unexplained infertility.
Thrombophilia
Inherited thrombophilia with recurrent pregnancy loss in Turkish women--a real phenomenon?
Thrombophilia
Inherited thrombophilias are not increased in "idiopathic" small-for-gestational-age pregnancies.
Thrombophilia
Is thrombophilia a major risk factor for deep vein thrombosis of the lower extremities among Lebanese patients?
Thrombophilia
Ischemic stroke subtypes and thrombophilia in young and elderly Brazilian stroke patients admitted to a rehabilitation hospital.
Thrombophilia
Lack of Association between Recurrent Pregnancy Loss and Inherited Thrombophilia in a Group of Colombian Patients.
Thrombophilia
Management and the pregnancy outcomes of patients positive for anti-parietal cell antibody.
Thrombophilia
Management of hereditary angioedema type I and homozygous MTHFR mutation during pregnancy.
Thrombophilia
May the morphological findings in the first-trimester abortion materials be indicative of inherited thrombophilia?
Thrombophilia
Meta-analysis of hypercoagulability genetic polymorphisms in perthes disease.
Thrombophilia
Methylenetetrahydrofolate Reductase C677T Polymorphism and Recurrent Pregnancy Loss Risk in Asian Population: A Meta-analysis.
Thrombophilia
Molecular pathophysiology of thrombotic states and their impact to laboratory diagnostics.
Thrombophilia
MTHFR C677T and Factor V Leiden in Recurrent Pregnancy Loss: A Study Among an Endogamous Group in North India.
Thrombophilia
MTHFR Gene Polymorphisms and Cardiovascular Risk Factors, Clinical-Imagistic Features and Outcome in Cerebral Venous Sinus Thrombosis.
Thrombophilia
Multifactorial Painful Leg Ulcers Due to Hyperhomocysteinemia, Plasminogen Activator Inhibitor-1 4G/5G Heterozygote Gene Mutation, and Beta Thalassemia Minor: A Case Report.
Thrombophilia
Multiplex primer extension reaction and capillary electrophoresis to study the frequency of thrombophilia-related mutations in a spanish population.
Thrombophilia
NONICHEMIC CENTRAL RETINAL VEIN OCCLUSION ASSOCIATED WITH HEREDITARY THROMBOPHYLIA.
Thrombophilia
Ocular vascular thrombotic events: a diagnostic window to familial thrombophilia (compound factor v leiden and prothrombin gene heterozygosity) and thrombosis.
Thrombophilia
Ocular vascular thrombotic events: central retinal vein and central retinal artery occlusions.
Thrombophilia
Outcome after kidney transplantation in children with thrombotic risk factors.
Thrombophilia
PAI-1 4G-4G and MTHFR 677TT in non-hepatitis C virus/hepatitis B virus-related liver cirrhosis.
Thrombophilia
PAI-1 4G-4G, MTHFR 677TT, V Leiden 506Q, and Prothrombin 20210A in Splanchnic Vein Thrombosis: Analysis of Individual Patient Data From Three Prospective Studies.
Thrombophilia
Pathologic features of the placenta in women with severe pregnancy complications and thrombophilia.
Thrombophilia
PlA2 Polymorphism of Platelet Glycoprotein IIb/IIIa and C677T Polymorphism of Methylenetetrahydrofolate Reductase (MTHFR), but Not Factor V Leiden and Prothrombin G20210A Polymorphisms, Are Associated with More Severe Forms of Legg-Calvé-Perthes Disease.
Thrombophilia
Polymorphism for mutation of cytosine to thymine at location 677 in the methylenetetrahydrofolate reductase gene is associated with recurrent early fetal loss.
Thrombophilia
Population study of thrombophilic markers and pharmacogenetic markers of warfarin prevalence in Bosnia and Herzegovina.
Thrombophilia
Portal and mesenteric vein thromboses in a patient with prothrombin G20210 mutation, elevated lipoprotein (a), and high factor VIII.
Thrombophilia
Preeclampsia and its interaction with common variants in thrombophilia genes.
Thrombophilia
Pregnancy outcome in patients with a history of recurrent spontaneous miscarriages and documented thrombophilias.
Thrombophilia
Prevalence and Multiplicity of Thrombophilia Genetic Polymorphisms of F V, MTHFR, F II, and PAI -I: A Cross-Sectional Study on a Healthy Jordanian Population.
Thrombophilia
Prevalence of factor V Leiden, prothrombin G20210A, and MTHFR G677A among 594 thrombotic Jordanian patients.
Thrombophilia
Primary thrombophilia in Mexico. II. Factor V G1691A (Leiden), prothrombin G20210A, and methylenetetrahydrofolate reductase C677T polymorphism in thrombophilic Mexican mestizos.
Thrombophilia
Primary thrombophilia in Mexico: a single tertiary referral hospital experience.
Thrombophilia
Primer-engineered multiplex PCR-RFLP for detection of MTHFR C677T, prothrombin G20210A and factor V Leiden mutations.
Thrombophilia
Protein C and protein S deficiencies are the most important risk factors associated with thrombosis in Chinese venous thrombophilic patients in Taiwan.
Thrombophilia
Prothrombin 20210 G-->A, MTHFR C677T mutations in women with venous thromboembolism associated with pregnancy.
Thrombophilia
Prothrombotic inherited abnormalities other than factor V Leiden mutation do not play a role in venous thrombosis in inflammatory bowel disease.
Thrombophilia
Recurrent cerebral venous thrombosis associated with heterozygote methylenetetrahydrofolate reductase C677T mutation and sickle cell trait without homocysteinemia: an autopsy case report and review of literature.
Thrombophilia
Recurrent miscarriage syndrome and infertility due to blood coagulation protein/platelet defects: a review and update.
Thrombophilia
Recurrent pregnancy loss in a subject with heterozygote factor V Leiden mutation; a case report.
Thrombophilia
Retinal vein occlusion in child with rare mutations in genes for thrombophilia.
Thrombophilia
Role of Polymorphisms in Factor V (FV Leiden), Prothrombin, Plasminogen Activator Inhibitor Type-1 (PAI-1), Methylenetetrahydrofolate Reductase (MTHFR) and Cystathionine ?-Synthase (CBS) Genes as Risk Factors for Thrombophilias.
Thrombophilia
Sequence variations within the genes related to hemostatic imbalance and their impact on coronary artery disease in Turkish population.
Thrombophilia
Severe 5,10-methylenetetrahydrofolate reductase deficiency and two MTHFR variants in an adolescent with progressive myoclonic epilepsy.
Thrombophilia
Severe arterial thrombophilia associated with a homozygous MTHFR gene mutation (A1298C) in a young man with Klinefelter syndrome.
Thrombophilia
Simultaneous genotyping of four single nucleotide polymorphisms associated with risk factors of hemostasis disorders.
Thrombophilia
Spontaneous pregnancies in patients with at least one failed IVF cycle after the management of autoimmune disorders, hereditary thrombophilia, and methylation disorders.
Thrombophilia
ST-elevation myocardial infarction, pulmonary embolism, and cerebral ischemic stroke in a patient with critically low levels of natural anticoagulants.
Thrombophilia
Statistical Correlations of the Spontaneous Abortion with Trombophilia and Other Associated Pathologies.
Thrombophilia
Sudden infant death syndrome, childhood thrombosis, and presence of genetic risk factors for thrombosis.
Thrombophilia
The 5, 10 methylenetetrahydrofolate reductase C677T mutation and risk of fetal loss: a case series and review of the literature.
Thrombophilia
The association between IUGR and maternal inherited thrombophilias: A case-control study.
Thrombophilia
The Association of Hereditary Prothrombotic Risk Factors with ST-Elevation Myocardial Infarction.
Thrombophilia
The prevalence of C677T mutation in the methylenetetrahydrofolate reductase gene and its association with venous thrombophilia in Taiwanese Chinese.
Thrombophilia
The Prevalence of Methylenetetrahydrofolate Reductase 677 C-T, Factor V 1691 G-A, and Prothrombin 20210 G-A Mutations in Healthy Populations in Setif, Algeria.
Thrombophilia
The relationship of mutations in the MTHFR, prothrombin, and PAI-1 genes to plasma levels of homocysteine, prothrombin, and PAI-1 in children and adults.
Thrombophilia
The role of point mutations in the genes, predisposing inherited thrombophilia in the pathogeneses of proximal and distal deep vein thrombosis in georgian population.
Thrombophilia
The use of B vitamins for cutaneous ulcerations mimicking pyoderma gangrenosum in patients with MTHFR polymorphism.
Thrombophilia
Thermolabile methylenetetrahydrofolate reductase and factor V Leiden in the risk of deep-vein thrombosis.
Thrombophilia
Thrombophilia in infancy: factor V Leiden and MTHFR or factor II double heterozygocity as a risk factor.
Thrombophilia
Thrombophilia in Patients With Lower Limbs Deep Veins Thrombosis (LDVT) Results of a Monocentric Survey on 103 Consecutive Outpatients.
Thrombophilia
Thrombophilia is common in women with idiopathic pregnancy loss and is associated with late pregnancy wastage.
Thrombophilia
Thrombophilia is significantly associated with severe preeclampsia: results of a large-scale, case-controlled study.
Thrombophilia
Thrombophilia Profile in Budd-Chiari Syndrome and Splanchnic Vein Thrombosis: A Study from Western India.
Thrombophilia
Thrombophilic genotypes in subjects with idiopathic antiphospholipid antibodies--prevalence and significance.
Thrombophilia
Thrombophilic mutations in Iranian patients with infertility and recurrent spontaneous abortion.
Thrombophilia
Thrombosis of sinus sagitalis during puerperium caused by thrombophilic gene mutation.
Thrombophilia
Treatable high homocysteine alone or in concert with five other thrombophilias in 1014 patients with thrombotic events.
Thrombophilia
Unusual presentation of a sarcoid patient: multiple arterial and venous thrombosis with chest lymphadenopathy.
Thrombophilia
Venous Thromboembolism after Allogeneic Pediatric Hematopoietic Stem Cell Transplantation: A Single-Center Study.
Thrombophilia
Vocal Cord Paralysis as the First Sign of Spontaneous Carotid Dissection in a Patient With Extracranial Internal Carotid Artery Aneurysm.
Thrombophilia
[Allele polymorphism analysis in coagulation factors F2, F5 and folate metabolism gene MTHFR by using microchip-based multiplex real time PCR].
Thrombophilia
[Cerebral sinovenous thrombosis in a newborn with mutation of MTHFR C677T treated with enoxaparin].
Thrombophilia
[FETAL LOSSES DURING THE MATURATION OF THE PLACENTA AND THE RELATIONSHIP WITH SOME PROCOAGULANT CONDITIONS.]
Thrombophilia
[Genetic thrombophilic defects (Factor V Leiden, prothrombin G20210A, MTHFR C677T) in women with recurrent fetal loss]
Thrombophilia
[Greater saphenous vein thrombosis and testosterone replacement therapy: an occasional association?]
Thrombophilia
[Massive pulmonary embolism in a patient with ulcerative colitis and hyperhomocysteinaemia -- a case report]
Thrombophilia
[Neonatal arterial ischemic stroke: Which thrombotic biological risk factors to investigate and which practical consequences?]
Thrombophilia
[Occurrence of gene mutations in factor V Leiden, prothrombin and methylenetetrahydrofolate reductase in patients with pre-eclampsia]
Thrombophilia
[Prevalence of methylenetetrahydrofolate reductase C677T mutation among patients with acute ischemic cerebrovascular disease in Aragon]
Thrombophilia
[The C677T mutation in the methylenetetrahydrofolate reductase gene and its association with deep vein thrombophilia in Shandong Hans]
Thrombophilia
[The role of 1691G>A (Leiden) mutation in Factor V gene, 20210G>A in prothrombin gene and 677C>T in MTHFR gene in etiology of early pregnancy loss].
Thrombophlebitis
Recurrent thrombophlebitis in a colon cancer patient with C677T heterozygous genotype for MTHFR treated with 5-fluorouracil-based adjuvant chemotherapy.
Thrombophlebitis
Superficial thrombophlebitis in varicose vein disease: the particular role of methylenetetrahydrofolate reductase.
Thrombosis
A common mutation in the methylenetetrahydrofolate reductase gene (C677T) increases the risk for deep-vein thrombosis in patients with mutant factor V (factor V:Q506).
Thrombosis
A new PCR-SSP typing method for six single-nucleotide polymorphisms impairing the blood-clotting cascade as well as T-cell stimulation.
Thrombosis
A newborn case with perinatal-lethal Gaucher disease due to R463H homozygosity complicated by C677T homozygosity in the MTHFR gene.
Thrombosis
Abdominal venous thrombosis in neonates and infants: role of prothrombotic risk factors - a multicentre case-control study. For the Childhood Thrombophilia Study Group.
Thrombosis
ABO blood groups and genetic risk factors for thrombosis in Croatian population.
Thrombosis
Acquired activated protein C resistance, thrombophilia and adverse pregnancy outcomes: a study performed in an irish cohort of pregnant women.
Thrombosis
Acute complete splenic infarction in a patient with Hirschsprung's disease and literature review of complete splenic infarction.
Thrombosis
Adaptive developmental plasticity in methylene tetrahydrofolate reductase (MTHFR) C677T polymorphism limits its frequency in South Indians.
Thrombosis
Anesthesia for cesarean section in a patient with placenta previa and methylenetetrahydrofolate reductase deficiency.
Thrombosis
Antiphospholipid antibodies in neonates with stroke--a unique entity or variant of antiphospholipid syndrome?
Thrombosis
Aortic Thrombus and Acute Pulmonary Embolism in an Individual Heterozygous for the MTHFR C677-T Mutation.
Thrombosis
Aortic thrombus and acute pulmonary embolism in an individual heterozygous for the MTHFR C677T mutation.
Thrombosis
Are factor V and prothrombin mutations associated with increased risk of oral cancer?
Thrombosis
Arterial thrombosis associated with factor V Leiden and methylenetetrahydrofolate reductase C677T mutation in childhood membranous glomerulonephritis.
Thrombosis
Assessment of genetic risk factors for thromboembolic complications in adults with idiopathic nephrotic syndrome.
Thrombosis
Association between polymorphism of MTHFR c.677C>T and risk of cardiovascular disease in Turkish population: a meta-analysis for 2.780 cases and 3.022 controls.
Thrombosis
Association between the methylene tetrahydrofolate reductase gene C677T mutation and colchicine unresponsiveness in Behcet's disease.
Thrombosis
Association between the methylenetetrahydrofolate reductase 677C>T polymorphism and the risk of secondary lymphoproliferative disease in patients with a first idiopathic thrombosis.
Thrombosis
Association of allelic variants of factor V Leiden, prothrombin and methylenetetrahydrofolate reductase with thrombosis or ocular involvement in Behçet's disease: A systematic review and meta-analysis.
Thrombosis
Association of Genetic Variants with Hyperhomocysteinemia in Indian Patients with Thrombosis.
Thrombosis
Association of Methylenetetrahydrofolate Reductase C677T Polymorphism with Hyperhomocysteinemia and Deep Vein Thrombosis in the Iranian Population.
Thrombosis
Association of various point mutations as risk factors for synthetic graft thrombosis in African American hemodialysis patients.
Thrombosis
AXILLARY ARTERY THROMBOSIS IN A NEWBORN HOMOZYGOUS FOR METHYLENETETRAHYDROFOLATE REDUCTASE (A1298C) MUTATION AND HETEROZYGOUS FOR FACTOR V LEIDEN (G506A) MUTATION.
Thrombosis
Biventricular Thrombi in a Patient With Heart Failure With Severely Reduced Ejection Fraction and Heterozygous Prothrombin 20210G/A and Homozygous Methylenetetrahydrofolate Reductase 677C/T Mutations.
Thrombosis
C677T substitution in the methylenetetrahydrofolate reductase gene as a risk factor for venous thrombosis and arterial disease in selected patients.
Thrombosis
Calcified thrombosis of the inferior vena cava extending to renal veins in a newborn with homozygous MTHFR a1298c mutation.
Thrombosis
Cardiology patient pages. Homocysteine and MTHFR mutations: relation to thrombosis and coronary artery disease.
Thrombosis
Cerebral sinovenous thrombosis associated with factor V Leiden and methylenetetrahydrofolate reductase A1298C mutation in adult membranous glomerulonephritis.
Thrombosis
Cerebral sinovenous thrombosis associated with MTHFR A1298C mutation in the newborn: a case report.
Thrombosis
Cilioretinal artery: Vasculogenesis might be promoted by plasminogen activator inhibitor-1 5G allele.
Thrombosis
Clinical significance of determining plasma homocysteine: case-control study on arterial and venous thrombotic patients.
Thrombosis
Coexistence of prothrombic risk factors and its relation to left ventricular thrombus in acute myocardial infarction.
Thrombosis
Coexistence of the methylenetetrahydrofolate reductase single-nucleotide polymorphism (C677T) in patients with the factor V Leiden or prothrombin G20210A polymorphisms.
Thrombosis
Common C677T polymorphism in the methylenetetrahydrofolate reductase gene increases the risk for deep vein thrombosis in patients with predisposition of thrombophilia.
Thrombosis
Compound heterozygosity for the C677T and A1298C mutations of the MTHFR gene in a case of hyperhomocysteinemia with recurrent deep thrombosis at young age.
Thrombosis
Congenital prothrombotic disorders in children with peripheral venous and arterial thromboses.
Thrombosis
Correlations between methylenetetrahydrofolate reductase gene polymorphisms and venous thromboembolism: A meta-analysis of 99 genetic association studies.
Thrombosis
Could genetic analysis be useful in reducing cerebrovascular risk in hypertensive subjects with hyperhomocysteinemia and patent foramen ovale? A 2-year follow-up study.
Thrombosis
Deep vein thrombosis after orthopedic surgery in a patient with type 1 von Willebrand disease and mutations in the MTHFR and beta-fibrinogen genes.
Thrombosis
Deep venous thrombosis and thrombophilic mutations in western Iran: association with factor V Leiden.
Thrombosis
Deletion polymorphism in the angiotensin-converting enzyme gene as a thrombophilic risk factor after hip arthroplasty.
Thrombosis
Differences in the frequency of the C677T mutation in the methylenetetrahydrofolate reductase (MTHFR) gene among the Lebanese population.
Thrombosis
Do thrombophilic gene mutations have a role on thromboembolic events in cancer patients?
Thrombosis
Dual mutation (MTHFR A1298C with PAI (4G) mutation) manifesting with bilateral lower limb gangrene in a neonate.
Thrombosis
Early Thrombosis of a Mitral Annuloplasty Ring in a Patient with MTHFR and Factor V Leiden Mutations.
Thrombosis
Easy, accurate and reliable screening for SNPs by ion pair/reverse phase HPLC: simultaneous detection of factor V G1691A, prothrombin G20210A and methylenetetrahydrofolate reductase C677T variants.
Thrombosis
Effect of methylenetetrahydrofolate reductase 677 C-T, 1298 A-C, and 1317 T-C on factor V 1691 mutation in Turkish deep vein thrombosis patients.
Thrombosis
Factor V Leiden and increased risk for arterial thrombotic disease in young Brazilian patients.
Thrombosis
Free-floating thrombus of the carotid artery with a homozygous methylenetetrahydrofolate reductase gene mutation: a case report.
Thrombosis
Frequency and association of 1691 (G>A) FVL, 20210 (G>A) PT and 677 (C>T) MTHFR with deep vein thrombosis in the population of Bosnia and Herzegovina.
Thrombosis
Genetic determinants of heritable venous thrombosis: genotyping methods for factor V(Leiden)A1691G, methylenetetrahydrofolate reductase C677T, prothrombin G20210A mutation, and algorithms for venous thrombosis investigations.
Thrombosis
Genetic factors associated with thrombosis in pregnancy in a United States population.
Thrombosis
Genetic polymorphism of 5,10-MTHFR reductase gene in offspring of patients with myocardial infarction.
Thrombosis
Genetic variations observed in arterial and venous thromboembolism--relevance for therapy, risk prevention and prognosis.
Thrombosis
Granulomatous reaction in mediastinal B-cell non-Hodgkin lymphoma and intracardiac thrombosis.
Thrombosis
Heterozygous methylenetetrahydrofolate reductase 677C-T gene mutation with mild hyperhomocysteinemia associated with intrauterine iliofemoral artery thrombosis.
Thrombosis
Heterozygous prothrombin 20210G/A mutation, associated with hyperhomocysteinemia, and homozygous methylenetetrahydrofolate reductase 677C/T mutation, in a patient with portal and mesenteric venous thrombosis.
Thrombosis
High prevalence of thrombophilic genotypes in patients with acute mesenteric vein thrombosis.
Thrombosis
Homocysteine, methylenetetrahydrofolate reductase polymorphism, antiphospholipid antibodies, and thromboembolic events in systemic lupus erythematosus: a retrospective cohort study.
Thrombosis
Hyperhomocysteinemia and C677T MTHFR Genotype in Patients With Retinal Vein Thrombosis.
Thrombosis
Hyperhomocysteinemia and Methylenetetrahydrofolate Reductase C677T Polymorphism in Cerebral Veno-sinus Thrombosis.
Thrombosis
Hyperhomocysteinemia and MTHFR C677T homozygosity in a vegetarian male with sinovenous thrombosis of the brain.
Thrombosis
Hyperhomocysteinemia and MTHFR C677T polymorphism in patients with portal vein thrombosis complicating liver cirrhosis.
Thrombosis
Hyperhomocysteinemia and of Methylenetetrahydrofolate Reductase (C677T) Genetic Polymorphism in Patients with Deep Vein Thrombosis.
Thrombosis
Hyperhomocysteinemia and the compound heterozygous state for methylene tetrahydrofolate reductase are independent risk factors for deep vein thrombosis among South Indians.
Thrombosis
Hyperhomocysteinemia, deep vein thrombosis and vitamin B12 deficiency in a metformin-treated diabetic patient.
Thrombosis
Hyperhomocysteinemia, low folate status, homozygous C677T mutation of the methylene tetrahydrofolate reductase and renal arterial thrombosis.
Thrombosis
Impact of maternal methylenetetrahydrofolate reductase C677T polymorphism on intervillous and decidual pathology with pregnancy loss.
Thrombosis
Impact of thrombophilic gene mutations on thrombosis risk in patients with gastrointestinal carcinoma.
Thrombosis
Influence of genetic predisposition to thrombosis on natural history of acute promyelocytic leukaemia. MRC Adult Leukaemia Working Party.
Thrombosis
Inherited thrombophilia: a possible cause of in utero vascular thrombosis in children with intestinal atresia.
Thrombosis
Inherited thrombophilias in pregnant patients: detection and treatment paradigm.
Thrombosis
Intra-operative detection of carotid free-floating thrombus in a symptomatic patient with a methylenetetrahydrofolate reductase gene mutation. Case report and literature review.
Thrombosis
Intracardiac Thrombosis Involving All Four Cardiac Chambers after Extracardiac Membranous Oxygenation Associated with MTHFR Mutations.
Thrombosis
Intrauterine upper limb ischemia associated with fetal thrombophilia: a case report and review of the literature.
Thrombosis
Investigation of potential biomarkers for thrombosis related diseases in Turkish Cypriot population.
Thrombosis
Methylenetetrahydrofolate reductase (MTHFR) C677T mutation in Turkish patients with thrombosis.
Thrombosis
Methylenetetrahydrofolate reductase C677T gene mutation and hyperhomocysteinemia in Budd-Chiari syndrome and portal vein thrombosis: A systematic review and meta-analysis of observational studies.
Thrombosis
Methylenetetrahydrofolate reductase C677T mutation and risk of retinal vein thrombosis.
Thrombosis
Methylenetetrahydrofolate Reductase C677T: Hypoplastic Left Heart and Thrombosis.
Thrombosis
Methylenetetrahydrofolate Reductase Gene Polymorphism (C677T) as a Risk Factor for Arterial Thrombosis in Georgian Patients.
Thrombosis
Methylenetetrahydrofolate reductase gene polymorphism: relation to blood pressure and cerebrovascular disease.
Thrombosis
Methylenetetrahydrofolate reductase homozygous mutation in a young boy with cerebellar infarction.
Thrombosis
Methylenetetrahydrofolate reductase polymorphism in healthy volunteers and its correlation with homocysteine levels in patients with thrombosis.
Thrombosis
Mobile right heart thrombus as a manifestation of homozygous mutation of MTHFR 1298 A>C.
Thrombosis
Molecular analysis of factor V Leiden, factor V Hong Kong, factor II G20210A, methylenetetrahydrofolate reductase C677T, and A1298C mutations related to Turkish thrombosis patients.
Thrombosis
Molecular Analysis of Prothrombotic Gene Variants in Venous Thrombosis: A Potential Role for Sex and Thrombotic Localization.
Thrombosis
MTHFR C677T mutations in liver cirrhosis with and without portal vein thrombosis.
Thrombosis
MTHFR C677TT, PAI1 4G-4G, V Leiden Q506, and prothrombin G20210A in hepatocellular carcinoma with and without portal vein thrombosis.
Thrombosis
Neonatal sinovenous thrombosis associated with homozygous thermolabile methylenetetrahydrofolate reductase in both mother and infant.
Thrombosis
No evidence for an increased risk of venous thrombosis in patients with factor V Leiden by the homozygous 677 C to T mutation in the methylenetetrahydrofolate-reductase gene.
Thrombosis
Outcome of primary glomerular disease in pediatric renal transplantation: a single-center experience.
Thrombosis
PAI-1 4G-4G and MTHFR 677TT in non-hepatitis C virus/hepatitis B virus-related liver cirrhosis.
Thrombosis
PAI-1 4G-4G, MTHFR 677TT, V Leiden 506Q, and Prothrombin 20210A in Splanchnic Vein Thrombosis: Analysis of Individual Patient Data From Three Prospective Studies.
Thrombosis
PAI-1 4G÷5G and MTHFR C677T polymorphisms increased the accuracy of two prediction scores for the risk of acute lower extremity deep vein thrombosis.
Thrombosis
PO-57 - Problems of diagnostics of rare localizations thrombosis in cancer patients.
Thrombosis
Polymorphisms in the methylenetetrahydrofolate reductase and methionine synthase reductase genes and homocysteine levels in Brazilian children.
Thrombosis
Portal Vein Thrombosis in a Preterm Newborn with Mutation of the MTHFR and PAI-1 Genes and Sepsis by Candida parapsilosis.
Thrombosis
Portal vein thrombosis in Egyptian patients with liver cirrhosis: Role of methylenetetrahydrofolate reductase C677T gene mutation.
Thrombosis
Possible Association Between the Methylenetetrahydrofolate Reductase Gene C677T Polymorphism and Preexisting Portal Vein Thrombosis in Liver Transplant Recipients.
Thrombosis
Prenatal diagnosis for severe methylenetetrahydrofolate reductase deficiency by linkage analysis and enzymatic assay.
Thrombosis
Prevalence of factor V G1691A (Leiden), prothrombin G20210A, and methylene tetrahydrofolate reductase C677T thrombophilic mutations in children with inflammatory bowel disease.
Thrombosis
Prevalence of factor V Leiden, FII G20210A, FXIII Val34Leu and MTHFR C677T polymorphisms in cancer patients with and without venous thrombosis.
Thrombosis
Prevalence of factor V leiden, MTHFR C677T and MTHFR A1298C polymorphisms in patients with deep vein thrombosis in Central Iran.
Thrombosis
Prevalence of factor V Leiden, prothrombin G20210A, and MTHFR G677A among 594 thrombotic Jordanian patients.
Thrombosis
Prevalence of hyperhomocysteinemia and the MTHFR C677T polymorphism in patients with arterial and venous thrombosis from North Western Russia.
Thrombosis
Prevalence of methylenetetrahydrofolate reductase C677T and its association with arterial and venous thrombosis in the Chinese population.
Thrombosis
Prevalence of prothrombin G20210A, factor V G1691A (Leiden), and methylenetetrahydrofolate reductase (MTHFR) C677T in seven different populations determined by multiplex allele-specific PCR.
Thrombosis
Primary thrombophilia in Mexico. II. Factor V G1691A (Leiden), prothrombin G20210A, and methylenetetrahydrofolate reductase C677T polymorphism in thrombophilic Mexican mestizos.
Thrombosis
Prospective evaluation of the risk conferred by factor V Leiden and thermolabile methylenetetrahydrofolate reductase polymorphisms in pregnancy.
Thrombosis
Prothrombin 20210A and oral contraceptive use as risk factors for cerebral venous thrombosis.
Thrombosis
Prothrombotic factors in neonates with cerebral thrombosis and intraventricular hemorrhage.
Thrombosis
Prothrombotic gene polymorphisms: possible contributors to hepatic artery thrombosis after orthotopic liver transplantation.
Thrombosis
Pulmonary Embolism in a Sarcoidosis Patient Double Heterozygous for Methylenetetrahydrofolate Reductase Gene Polymorphisms and Factor V Leiden and Homozygous for the D-Allele of Angiotensin Converting Enzyme Gene.
Thrombosis
Recurrent cerebral venous thrombosis associated with heterozygote methylenetetrahydrofolate reductase C677T mutation and sickle cell trait without homocysteinemia: an autopsy case report and review of literature.
Thrombosis
Recurrent thrombosis in a patient with pseudohomozygous activated protein C resistance and homozygosity for MTHFR gene polymorphism C677T.
Thrombosis
Reduced in vivo oxidative stress following 5-methyltetrahydrofolate supplementation in patients with early-onset thrombosis and 677TT methylenetetrahydrofolate reductase genotype.
Thrombosis
Role of Polymorphisms in Factor V (FV Leiden), Prothrombin, Plasminogen Activator Inhibitor Type-1 (PAI-1), Methylenetetrahydrofolate Reductase (MTHFR) and Cystathionine ?-Synthase (CBS) Genes as Risk Factors for Thrombophilias.
Thrombosis
Screening for inherited thrombophilia might be warranted among Eastern Mediterranean sickle-beta-0 thalassemia patients.
Thrombosis
Segmental renal artery thrombosis secondary to methylene tetrahydrofolate reductase mutation: an unusual presentation.
Thrombosis
Significance of the use of the ViennaLab "Cardiovascular Disease panel" (CVD) Assay as a reflex test for the "Factor V/II/MTHFR Assay".
Thrombosis
Splenic thrombosis in three patients with moderate hyperhomocysteinemia, low folate and the C677T variant of the methylenetetrahydrofolate reductase (MTHFR) gene.
Thrombosis
Sudden infant death syndrome, childhood thrombosis, and presence of genetic risk factors for thrombosis.
Thrombosis
The 19-bp deletion of dihydrofolate reductase (DHFR), methylenetetrahydrofolate reductase (MTHFR) C677T, Factor V Leiden, prothrombin G20210A polymorphisms in cancer patients with and without thrombosis.
Thrombosis
The 677T genotype of the common MTHFR thermolabile variant and fasting homocysteine in childhood venous thrombosis.
Thrombosis
The dose-response relation between serum homocysteine and cardiovascular disease: implications for treatment and screening.
Thrombosis
The End of a Long Debate: Methylenetetrahydrofolate Reductase Gene Polymorphisms do not Increase Thrombosis Risk.
Thrombosis
The frequency of factor V Leiden and concomitance of factor V Leiden with prothrombin G20210A mutation and methylene tetrahydrofolate reductase C677T gene mutation in healthy population of Denizli, Aegean region of Turkey.
Thrombosis
The impact of the search for thrombophilia risk factors among antiphospholipid syndrome patients with thrombosis.
Thrombosis
The influence of age, sex, vitamin B(12), folate levels and methylenetetrahydrofolate reductase C677T genetic mutations on plasma homocysteine in the Chinese population.
Thrombosis
The Methylenetetrahydrofolate Reductase Polymorphism (MTHFR c.677C>T) and Elevated Plasma Homocysteine Levels in a U.S. Pediatric Population with Incident Thromboembolism.
Thrombosis
The MTHFR 677TT and 677CT/1298AC genotypes in Cypriot patients may be predisposing to hypertensive nephrosclerosis and chronic renal failure.
Thrombosis
The prevalence of C677T mutation in the methylenetetrahydrofolate reductase gene and its association with venous thrombophilia in Taiwanese Chinese.
Thrombosis
The prevalence of factor V (G1691A), MTHFR (C677T) and PT (G20210A) gene mutations in arterial thrombosis.
Thrombosis
The relationship between factor V Leiden, prothrombin G20210A, and MTHFR mutations and the first major thrombotic episode in polycythemia vera and essential thrombocythemia.
Thrombosis
The relationship of mutations in the MTHFR, prothrombin, and PAI-1 genes to plasma levels of homocysteine, prothrombin, and PAI-1 in children and adults.
Thrombosis
The Role of Factor V Leiden, Prothrombin G20210A, and MTHFR C677T Mutations in Neonatal Cerebral Sinovenous Thrombosis.
Thrombosis
The role of point mutations in the genes, predisposing inherited thrombophilia in the pathogeneses of proximal and distal deep vein thrombosis in georgian population.
Thrombosis
The role of vitamin B12 in fasting hyperhomocysteinemia and its interaction with the homozygous C677T mutation of the methylenetetrahydrofolate reductase (MTHFR) gene. A case-control study of patients with early-onset thrombotic events.
Thrombosis
Thrombophilic factors are not the leading cause of thrombosis in Behçet's disease.
Thrombosis
Thrombophilic genetic factors PAI-1 4G-4G and MTHFR 677TT as risk factors of alcohol, cryptogenic liver cirrhosis and portal vein thrombosis, in a Caucasian population.
Thrombosis
Thrombophilic genotypes in subjects with idiopathic antiphospholipid antibodies--prevalence and significance.
Thrombosis
Thrombophilic predisposition in stroke and venous thromboembolism in Danish patients.
Thrombosis
Thrombosis Related ABO, F5, MTHFR, and FGG Gene Polymorphisms in Morbidly Obese Patients.
Thrombosis
Thrombotic genetic risk factors and warfarin pharmacogenetic variants in São Miguel's healthy population (Azores).
Thrombosis
Thrombus obstructing the right ventricle outflow tract in a neonate with methylenetetrahydrofolate reductase 677TT genotype.
Thrombosis
Thyroid vein thrombosis in a young woman with methylenetetrahydrofolate reductase gene mutation receiving cyproterone acetate/ethinylestradiol treatment for polycystic ovary syndrome: a case report.
Thrombosis
Tricuspid valve thrombus and pulmonary embolus in an infant with homozygous thermolabile methylenetetrahydrofolate reductase and heterozygous prothrombin G20210A variant.
Thrombosis
Venous thromboembolism, factor V Leiden, and methylenetetrahydrofolate reductase in a sickle cell anemia patient.
Thrombosis
[Allele polymorphism analysis in coagulation factors F2, F5 and folate metabolism gene MTHFR by using microchip-based multiplex real time PCR].
Thrombosis
[Cerebral sinovenous thrombosis in a newborn with mutation of MTHFR C677T treated with enoxaparin].
Thrombosis
[Genetic trombophilia and markers of endotelial activation in patients with preeclampsia]
Thrombosis
[Homocysteine, 5,10-methylenetetrahydrofolate reductase and deep venous thrombosis. Survey of 120 patients in internal medicine]
Thrombosis
[Modern approaches to treatment of thrombosis in pregnant women, carriers of hereditary anomalies - f-v-leiden and g20210a mutation.]
Thrombosis
[Mutation of a 5,10-methylenetetrahydrofolate reductase gene in systemic lupus erythematosis and antiphospholipid syndrome]
Thrombosis
[Neonatal renal vein thrombosis in a heterozygous carrier of both factor V Leiden and the MTHFR gene mutation.]
Thrombosis
[Portal and mesenteric vein thrombosis associated with hyperhomocysteinemia and pernicious anemia in a patient heterozygous for the MTHFR C677T mutation.]
Thrombosis
[Study of the genetic markers of thrombosis in hypertensive patients of the title population in the Republic of Mordovia]
Thrombosis
[Thrombophilic disorders in children and adolescents with portal vein thrombosis]
Thrombosis
[Type I antithrombin deficiency as a cause of arterial and venous thrombosis in a family with severe thrombophilia]
Thrombotic Microangiopathies
The TT genotype of the C677T polymorphism in the methylentetrahydrofolate reductase as a risk factor in thrombotic microangiopathies: results from a pilot study.
Thrombotic Stroke
Association of three-gene interaction among MTHFR, ALOX5AP and NOTCH3 with thrombotic stroke: a multicenter case-control study.
Thrombotic Stroke
Elevated plasma homocysteine was associated with hemorrhagic and ischemic stroke, but methylenetetrahydrofolate reductase gene C677T polymorphism was a risk factor for thrombotic stroke: a Multicenter Case-Control Study in China.
Thrombotic Stroke
Interaction of genetic risk factors confers higher risk for thrombotic stroke in male Chinese: a multicenter case-control study.
Thyroid Cancer, Papillary
Polymorphisms of methylenetetrahydrofolate reductase and glutathione S-transferase are not associated with the risk of papillary thyroid cancer in Korean population.
Thyroid Cancer, Papillary
Polymorphisms of selected xenobiotic genes contribute to the development of papillary thyroid cancer susceptibility in Middle Eastern population.
Thyroid Diseases
Association of polymorphisms in DNMT1, DNMT3A, DNMT3B, MTHFR and MTRR genes with global DNA methylation levels and prognosis of autoimmune thyroid disease.
Thyroid Diseases
MTHFR gene polymorphisms in hypothyroidism and hyperthyroidism among Jordanian females.
Thyroid Diseases
Significant Association Between MTHFR C677T Polymorphism and Thyroid Cancer Risk: Evidence from a Meta-Analysis.
Thyroid Neoplasms
An increased risk of differentiated thyroid carcinoma in Iran with the 677C?T homozygous polymorphism in the MTHFR Gene.
Thyroid Neoplasms
Association between MTHFR C677T polymorphism and thyroid cancer risk: a meta-analysis.
Thyroid Neoplasms
Association of the functional polymorphism C677T in the methylenetetrahydrofolate reductase gene with colorectal, thyroid, breast, ovarian, and cervical cancers.
Thyroid Neoplasms
Increased T-allele frequency of 677 C>T polymorphism in the methylenetetrahydrofolate reductase gene in differentiated thyroid carcinoma.
Thyroid Neoplasms
Interaction between alcohol consumption and methylenetetrahydrofolate reductase polymorphisms in thyroid cancer risk: National Cancer Center cohort in Korea.
Thyroid Neoplasms
Polymorphisms in MTHFR, MTR, RFC1 and CßS genes involved in folate metabolism and thyroid cancer: a case-control study.
Thyroid Neoplasms
Significant Association Between MTHFR C677T Polymorphism and Thyroid Cancer Risk: Evidence from a Meta-Analysis.
Thyroid Neoplasms
The association between the C677T polymorphism in MTHFR gene and the risk of thyroid cancer: a meta-analysis.
Thyroiditis, Autoimmune
Statistical Correlations of the Spontaneous Abortion with Trombophilia and Other Associated Pathologies.
Thyrotoxicosis
Cerebral sinus venous thrombosis in a subject with thyrotoxicosis and MTHFR gene polymorphism.
Triple Negative Breast Neoplasms
The methylenetetrahydrofolate reductase (MTHFR) C677T gene polymorphism is associated with breast cancer subtype susceptibility in southwestern China.
Trisomy 18 Syndrome
Maternal folate polymorphisms and the etiology of human nondisjunction.
Trisomy 18 Syndrome
[Association of MTHFR and MTRR genes polymorphisms with non-disjunctions of chromosomes 18 and 21].
Turner Syndrome
C677T and A1298C Polymorphisms of MTHFR Gene and Their Relation to Homocysteine Levels in Turner Syndrome.
Turner Syndrome
Methylenetetrahydrofolate reductase gene polymorphisms in Egyptian Turner Syndrome patients.
Turner Syndrome
Prevalence of the polymorphism MTHFR A1298C and not MTHFR C677T is related to chromosomal aneuploidy in Brazilian Turner Syndrome patients.
Urea Cycle Disorders, Inborn
Inborn Errors of Metabolism Associated With Autism Spectrum Disorders: Approaches to Intervention.
Uremia
Mutation (677 C to T) in the methylenetetrahydrofolate reductase gene aggravates hyperhomocysteinemia in hemodialysis patients.
Uremia
[Methylenetetrahydrofolate reductase gene polymorphism and plasma homocysteine levels in hemodialysing patients]
Urinary Bladder Neoplasms
Association between methylenetetrahydrofolate reductase gene rs1801131 A/C polymorphism and urinary tumors' susceptibility.
Urinary Bladder Neoplasms
Association between MTHFR Ala222Val (rs1801133) polymorphism and bladder cancer susceptibility: a systematic review and meta-analysis.
Urinary Bladder Neoplasms
Combined effect of NAT2, MTR and MTHFR genotypes and tobacco on bladder cancer susceptibility in Tunisian population.
Urinary Bladder Neoplasms
Genetic polymorphisms of MTHFR and aberrant promoter hypermethylation of the RASSF1A gene in bladder cancer risk in a Chinese population.
Urinary Bladder Neoplasms
Genetic susceptibility of methylenetetrahydrofolate reductase (MTHFR) gene C677T, A1298C, and G1793A polymorphisms with risk for bladder transitional cell carcinoma in men.
Urinary Bladder Neoplasms
Genetic susceptibility to cancer: the role of polymorphisms in candidate genes.
Urinary Bladder Neoplasms
Genetic variation in Glutathione S-Transferase Omega-1, Arsenic Methyltransferase and Methylene-tetrahydrofolate Reductase, arsenic exposure and bladder cancer: a case-control study.
Urinary Bladder Neoplasms
Investigation of genetic polymorphisms and smoking in a bladder cancer case-control study in Argentina.
Urinary Bladder Neoplasms
Lack of association between MTHFR Ala222Val and Glu429Ala polymorphisms and bladder cancer risk: A meta-analysis of case-control studies.
Urinary Bladder Neoplasms
Methylenetetrahydrofolate reductase (MTHFR) variants and bladder cancer: a population-based case-control study.
Urinary Bladder Neoplasms
Methylenetetrahydrofolate reductase and methionine synthase polymorphisms and risk of bladder cancer in a Tunisian population.
Urinary Bladder Neoplasms
MTHFR C677T and A1298C polymorphisms were associated with bladder cancer risk and disease progression: a meta-analysis.
Urinary Bladder Neoplasms
MTHFR Gene Polymorphisms and Bladder Cancer Susceptibility: a Meta-Analysis Including Race, Smoking Status and Tumour Stage.
Urinary Bladder Neoplasms
MTHFR Gene Polymorphisms in Bladder Cancer in the Turkish Population.
Urinary Bladder Neoplasms
Polymorphisms in DNA repair and metabolic genes in bladder cancer.
Urinary Bladder Neoplasms
Polymorphisms in NQO1 and the clinical course of urinary bladder neoplasms.
Urinary Bladder Neoplasms
Polymorphisms in one-carbon metabolism and trans-sulfuration pathway genes and susceptibility to bladder cancer.
Urinary Bladder Neoplasms
Polymorphisms in one-carbon metabolism pathway genes and risk for bladder cancer in a Tunisian population.
Urinary Bladder Neoplasms
Polymorphisms of folate metabolic genes and susceptibility to bladder cancer: a case-control study.
Urinary Bladder Neoplasms
Polymorphisms of methylenetetrahydrofolate reductase and methionine synthase genes and bladder cancer risk: a case-control study with meta-analysis.
Urinary Bladder Neoplasms
Quantitative assessment of the association between MHTFR C677T (rs1801133, Ala222Val) polymorphism and susceptibility to bladder cancer.
Urinary Bladder Neoplasms
Smoking and polymorphisms in folate metabolizing genes and their effects on the histological stage and grade for bladder tumors.
Urolithiasis
Relationship of Cholelithiasis and Urolithiasis with Methylenetetrahydrofolate Reductase Polymorphisms.
Uterine Cervical Neoplasms
A case-control nutrigenomic study on the synergistic activity of folate and vitamin B12 in cervical cancer progression.
Uterine Cervical Neoplasms
A relationship between methylenetetrahydrofolate reductase variants and the development of invasive cervical cancer.
Uterine Cervical Neoplasms
Allelic variations in 5, 10-methylenetetrahydrofolate reductase gene and susceptibility to cervical cancer in Indian women.
Uterine Cervical Neoplasms
Association between Methylenetetrahydrofolate Reductase C677T Polymorphism and Susceptibility to Cervical Cancer: A Meta-Analysis.
Uterine Cervical Neoplasms
Association between MTHFR C677T, MTHFR A1298C and MS A2756G polymorphisms and risk of cervical intraepithelial neoplasia II/III and cervical cancer: A meta-analysis.
Uterine Cervical Neoplasms
Association between the MTHFR A1298C polymorphism and risk of cancer: evidence from 265 case-control studies.
Uterine Cervical Neoplasms
C677T polymorphism of methylenetetrahydrofolate reductase may contribute to cervical cancer risk in complete over-dominant model.
Uterine Cervical Neoplasms
Cervical cancer with polymorphism in MTHFR C677T gene: a systematic review and meta-analysis.
Uterine Cervical Neoplasms
Common polymorphisms in methylenetetrahydrofolate reductase gene are associated with risks of cervical intraepithelial neoplasia and cervical cancer in women with low serum folate and vitamin B12.
Uterine Cervical Neoplasms
Effects of methylenetetrahydrofolate reductase single-nucleotide polymorphisms on breast, cervical, ovarian, and endometrial cancer susceptibilities.
Uterine Cervical Neoplasms
Folate and choline metabolism gene variants and development of uterine cervical carcinoma.
Uterine Cervical Neoplasms
Homocysteine levels are associated with cervical cancer independent of methylene tetrahydrofolate reductase gene (MTHFR) polymorphisms in Indian population.
Uterine Cervical Neoplasms
Impact of methylenetetrahydrofolate reductase (MTHFR) codon (677) and methionine synthase (MS) codon (2756) on risk of cervical carcinogenesis in North Indian population.
Uterine Cervical Neoplasms
Increase in the prevalence of the MTHFR 677 TT polymorphism in women born since 1959: potential implications for folate requirements.
Uterine Cervical Neoplasms
Lack of association between methylenetetrahydrofolate reductase C677T polymorphism, HPV infection and cervical intraepithelial neoplasia in Brazilian women.
Uterine Cervical Neoplasms
Methylenetetrahydrofolate reductase (MTHFR) and susceptibility for (pre)neoplastic cervical disease.
Uterine Cervical Neoplasms
Methylenetetrahydrofolate reductase (MTHFR) polymorphism increases the risk of cervical intraepithelial neoplasia.
Uterine Cervical Neoplasms
Methylenetetrahydrofolate Reductase C677T Polymorphism and Cervical Cancer Risk: a Meta-Analysis.
Uterine Cervical Neoplasms
Methylenetetrahydrofolate reductase C677T polymorphism and susceptibility to cervical cancer and cervical intraepithelial neoplasia: a meta-analysis.
Uterine Cervical Neoplasms
Methylenetetrahydrofolate reductase polymorphism C677T is not associated to the risk of cervical dysplasia.
Uterine Cervical Neoplasms
MTHFR C677T and A1298C polymorphisms and cervical carcinoma susceptibility: meta-analyses based on 4421 individuals.
Uterine Cervical Neoplasms
MTHFR C677T polymorphism was an ethnicity-dependent risk factor for cervical cancer development: evidence based on a meta-analysis.
Uterine Cervical Neoplasms
MTHFR/p53 polymorphisms as genetic factors for cervical intraepithelial neoplasia and cervical cancer in HPV-infected Mexican women.
Uterine Cervical Neoplasms
Polymorphism in folate- and methionine-metabolizing enzyme and aberrant CpG island hypermethylation in uterine cervical cancer.
Uterine Cervical Neoplasms
The association between MTHFR 677C>T polymorphism and cervical cancer: evidence from a meta-analysis.
Uterine Cervical Neoplasms
The association between MTHFR polymorphisms and cervical cancer risk: a system review and meta analysis.
Uterine Cervical Neoplasms
The effect of methylenetetrahydrofolate reductase polymorphism C677T on cervical cancer in Korean women.
Uterine Cervical Neoplasms
The effect of methylenetetrahydrofolate reductase polymorphisms on susceptibility to human papilloma virus infection and cervical cancer.
Uterine Cervical Neoplasms
The effects of polymorphisms in methylenetetrahydrofolate reductase (MTHFR), methionine synthase (MTR), and methionine synthase reductase (MTRR) on the risk of cervical intraepithelial neoplasia and cervical cancer in Korean women.
Uterine Cervical Neoplasms
The SNP rs4846048 of MTHFR enhances the cervical cancer risk through association with miR-522: A preliminary report.
Uterine Cervical Neoplasms
[Study on the relationship between the MTHFR polymorphism, the level of the folic acid and the cervical cancer susceptibility].
Uterine Cervical Neoplasms
[The effect of MTHFR polymorphisms, pregnancy and first intercourse on cervical cancer in a population from the Northeastern Mexico]
Vaginosis, Bacterial
Polymorphisms in the MTHRF, VDR, MMP-9 and IL-? genes and the risk of premature rupture of membranes.
Vaginosis, Bacterial
Socio-economic disparities in preterm birth: causal pathways and mechanisms.
Varicocele
Is methylenetetrahydrofolate reductase (MTHFR) gene A1298C polymorphism related with varicocele risk?
Varicose Veins
Morphology and Progression in Primary Varicose Vein Disorder Due to 677C>T and 1298A>C Variants of MTHFR.
Varicose Veins
Polymorphisms in the MTHFR and MTR genes and the risk of varicose veins in ethnical Russians.
Varicose Veins
Prevalence of the methylenetetrahydrofolate reductase (MTHFR) C677T mutation in patients with varicose veins of lower limbs.
Varicose Veins
Superficial thrombophlebitis in varicose vein disease: the particular role of methylenetetrahydrofolate reductase.
Vascular Calcification
MTHFR C677T Polymorphism as a Risk Factor for Vascular Calcification in Chronic Hemodialysis Patients.
Vascular Diseases
A C677T methylenetetrahydrofolate reductase (MTHFR) polymorphism and G20210A mutation in the prothrombin gene of sickle cell anemia patients from Northeast Brazil.
Vascular Diseases
A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase.
Vascular Diseases
A common haplotype for the 677T thermolabile variant of the 5,10-methylenetetrahydrofolate reductase gene in thrombophilic patients and controls.
Vascular Diseases
A second common variant in the methylenetetrahydrofolate reductase (MTHFR) gene and its relationship to MTHFR enzyme activity, homocysteine, and cardiovascular disease risk.
Vascular Diseases
A Structured-based Model for the Decreased Activity of Ala222Val and Glu429Ala Methylenetetrahydrofolate Reductase (MTHFR) Mutants.
Vascular Diseases
Analysis of genetic polymorphism of methylenetetrahydrofolate reductase in a large ethnic Hakka population in southern China.
Vascular Diseases
Analysis of the 677 C-->T mutation of the methylenetetrahydrofolate reductase gene in different ethnic groups.
Vascular Diseases
C677T and A1298C polymorphisms of the methylenetetrahydrofolate reductase gene: incidence and effect of combined genotypes on plasma fasting and post-methionine load homocysteine in vascular disease.
Vascular Diseases
C677T MTHFR mutation and factor V Leiden mutation in patients with TIA/minor stroke: a case-control study.
Vascular Diseases
C677T substitution in the methylenetetrahydrofolate reductase gene as a risk factor for venous thrombosis and arterial disease in selected patients.
Vascular Diseases
Cardiac allograft vascular disease after orthotopic heart transplantation: methylenetetrahydrofolate reductase gene polymorphism C677T does not account for rapidly progressive forms.
Vascular Diseases
Carriage of the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism does not influence the first and second trimester uterine artery Doppler flow.
Vascular Diseases
Case-control study of the frequency of thrombophilic disorders in couples with late foetal loss and no thrombotic antecedent--the Nîmes Obstetricians and Haematologists Study5 (NOHA5).
Vascular Diseases
Cerebral sinovenous thrombosis associated with MTHFR A1298C mutation in the newborn: a case report.
Vascular Diseases
Combined heterozygosity for methylenetetrahydrofolate reductase (MTHFR) mutations C677T and A1298C is associated with abruptio placentae but not with intrauterine growth restriction.
Vascular Diseases
Common methylenetetrahydrofolate reductase gene mutation leads to hyperhomocysteinemia but not to vascular disease: the result of a meta-analysis.
Vascular Diseases
Common mutation in methylenetetrahydrofolate reductase. Correlation with homocysteine and other risk factors for vascular disease.
Vascular Diseases
Common mutation in methylenetetrahydrofolate reductase. Correlation with homocysteine metabolism and late-onset vascular disease.
Vascular Diseases
Determinants of fasting and post-methionine homocysteine levels in families predisposed to hyperhomocysteinemia and premature vascular disease.
Vascular Diseases
Does the polymorphism 677C-T of the 5,10-methylenetetrahydrofolate reductase gene contribute to homocysteine-related vascular disease?
Vascular Diseases
Effect of Mthfr genotype on diet-induced hyperhomocysteinemia and vascular function in mice.
Vascular Diseases
Effect of MTHFR genotypes and hyperhomocysteinemia on patient and graft survival in kidney transplant recipients.
Vascular Diseases
Endoplasmic reticulum stress increases the expression of methylenetetrahydrofolate reductase through the IRE1 transducer.
Vascular Diseases
Ethnic differences in the frequency of the C677T mutation in the methylenetetrahydrofolate reductase (MTHFR) gene in healthy Israeli populations.
Vascular Diseases
Factor V Leiden and thermolabile methylenetetrahydrofolate reductase in extreme old age.
Vascular Diseases
Fasting, postprandial, and post-methionine-load homocysteinaemia and methylenetetrahydrofolate reductase polymorphism in vascular disease.
Vascular Diseases
Frequency of MTHFR G1793A polymorphism in individuals with early coronary artery disease: cross-sectional study.
Vascular Diseases
Frequency of the 677 C-->T mutation of the methylenetetrahydrofolate reductase gene among Kuwaiti sickle cell disease patients.
Vascular Diseases
Functional characterization of human methylenetetrahydrofolate reductase in Saccharomyces cerevisiae.
Vascular Diseases
Genetic determinants of hyperhomocysteinaemia: the roles of cystathionine beta-synthase and 5,10-methylenetetrahydrofolate reductase.
Vascular Diseases
Genetic investigation of methylenetetrahydrofolate reductase (MTHFR) and catechol-O-methyl transferase (COMT) in multiple sclerosis.
Vascular Diseases
Genetic polymorphism of methylenetetrahydrofolate reductase as a risk factor for diabetic nephropathy in Chinese type 2 diabetic patients.
Vascular Diseases
Higher incidence of C677T polymorphism of the MTHFR gene in North Indian patients with vascular disease.
Vascular Diseases
Homocysteine, folate, methylene tetrahydrofolate reductase genotype and vascular morbidity in diabetic subjects.
Vascular Diseases
Hyperhomocysteinemia and polymorphisms of the methylenetetrahydrofolate gene in hemodialysis and peritoneal dialysis patients.
Vascular Diseases
Hyperhomocysteinemia but not the C677T mutation of methylenetetrahydrofolate reductase is an independent risk determinant of carotid wall thickening. The Perth Carotid Ultrasound Disease Assessment Study (CUDAS)
Vascular Diseases
Methylenetetrahydrofolate reductase (MTHFR) C677T mutation in Turkish patients with thrombosis.
Vascular Diseases
Methylenetetrahydrofolate reductase (MTHFR) polymorphisms and risk of molecularly defined subtypes of childhood acute leukemia.
Vascular Diseases
Methylenetetrahydrofolate reductase (MTHFR): the incidence of mutations C677T and A1298C in the Ashkenazi Jewish population.
Vascular Diseases
METHYLENETETRAHYDROFOLATE REDUCTASE C677T POLYMORPHISM IN PATIENTS WITH HENOCH-SCHÖNLEIN PURPURA.
Vascular Diseases
Methylenetetrahydrofolate reductase gene A222V polymorphism and risk of ischemic stroke.
Vascular Diseases
Methylenetetrahydrofolate reductase gene polymorphism, homocysteine and risk of macroangiopathy in Type 2 diabetes mellitus.
Vascular Diseases
Methylenetetrahydrofolate reductase gene polymorphism, hyperhomocysteinemia and occlusive retinal vascular disease in type 2 diabetic and non-diabetic subjects.
Vascular Diseases
Methylenetetrahydrofolate reductase gene polymorphisms in 13 Chinese ethnic populations.
Vascular Diseases
Methylenetetrahydrofolate reductase polymorphisms as risk factors for retinal venous occlusive disease: A literature review.
Vascular Diseases
Migraine and coronary artery disease: an open study on the genetic polymorphism of the 5, 10 methylenetetrahydrofolate (MTHFR) and angiotensin I-converting enzyme (ACE) genes.
Vascular Diseases
Molecular and clinical characterisation of homocystinuria in two Austrian families with cystathionine beta-synthase deficiency.
Vascular Diseases
MTHFR gene variant is not associated with diabetic nephropathy in Japanese.
Vascular Diseases
Mutations of the MTHFR gene (428C>T and [458G>T+459C>T]) markedly decrease MTHFR enzyme activity.
Vascular Diseases
Na VPA-induced acute ischemic stroke in an epileptic patient with methylenetetrahydrofolate reductase gene polymorphism.
Vascular Diseases
Plasma homocysteine levels related to interactions between folate status and methylenetetrahydrofolate reductase: a study in 52 healthy subjects.
Vascular Diseases
Polymorphism of the methylenetetrahydrofolate reductase gene association with homocysteine and ischemic stroke in type 2 diabetes.
Vascular Diseases
Polymorphisms of methylenetetrahydrofolate reductase (MTHFR) and susceptibility to pediatric acute lymphoblastic leukemia in a German study population.
Vascular Diseases
Prevalence of hyperhomocysteinemia and the MTHFR C677T polymorphism in patients with arterial and venous thrombosis from North Western Russia.
Vascular Diseases
Prevalence of the mutation C677 --> T in the methylene tetrahydrofolate reductase gene among distinct ethnic groups in Brazil.
Vascular Diseases
Prevalence of variants in methylenetetrahydrofolate reductase and the severity of pulmonary vascular disease.
Vascular Diseases
Role of Inherited Thrombophilia Risk Factors in Patients with CKD-5 Receiving Haemodialysis.
Vascular Diseases
Sequential multiple retinal vein occlusions and transient ischemic attack in MTHFR polymorphism and protein S deficiency.
Vascular Diseases
Serum folate, total homocysteine levels and methylenetetrahydrofolate reductase 677C>T polymorphism in young healthy female Japanese.
Vascular Diseases
Serum homocysteine, MTHFR gene polymorphism, and carotid intimal-medial thickness in NIDDM subjects.
Vascular Diseases
Study on homocysteine levels and methylenetetrahydrofolate reductase gene variant (C677T) in a population of Buenos Aires city.
Vascular Diseases
Targeted insertion of two Mthfr promoters in mice reveals temporal- and tissue-specific regulation.
Vascular Diseases
The (Ala-Val) mutation of methylenetetrahydrofolate reductase as a genetic risk factor for vascular disease in non-insulin-dependent diabetic patients.
Vascular Diseases
The 1298A-->C polymorphism in methylenetetrahydrofolate reductase (MTHFR): in vitro expression and association with homocysteine.
Vascular Diseases
The common 'thermolabile' variant of methylene tetrahydrofolate reductase is a major determinant of mild hyperhomocysteinaemia.
Vascular Diseases
The effect of MTHFR c.677C>T on plasma homocysteine levels depends on health, age and smoking.
Vascular Diseases
The high prevalence of thermolabile 5-10 methylenetetrahydrofolate reductase (MTHFR) in Italians is not associated to an increased risk for coronary artery disease (CAD).
Vascular Diseases
The influence of genetic and environmental factors on plasma homocysteine concentrations in a population at high risk for coronary artery disease.
Vascular Diseases
The methylenetetrahydrofolate reductase 677 C-->T polymorphism and preeclampsia in two populations.
Vascular Diseases
The methylenetetrahydrofolate reductase gene variant C677T influences susceptibility to migraine with aura.
Vascular Diseases
The MTHFR C677T Polymorphism and Risk of Intracerebral Hemorrhage in a Chinese Han Population.
Vascular Diseases
The relationship between the C677T polymorphism of the MTHFR gene and serum levels of luteinizing hormone in males with erectile dysfunction.
Vascular Diseases
The thermolabile variant 677C-->T can further reduce activity when expressed in cis with severe mutations for human methylenetetrahydrofolate reductase.
Vascular Diseases
Thermolabile 5,10-methylenetetrahydrofolate reductase as a cause of mild hyperhomocysteinemia.
Vascular Diseases
Thermolabile methylenetetrahydrofolate reductase in patients with coronary artery disease.
Vascular Diseases
Thermolabile methylenetetrahydrofolate reductase, homocysteine, and cardiovascular disease risk: the European Concerted Action Project.
Vascular Diseases
Thermolabile methylenetetrahydrofolate reductase: an inherited risk factor for coronary artery disease.
Vascular Diseases
[Genetic polymorphisms of methylenetetrahydrofolate reductase and methionine synthase: association with homocysteine metabolism and late-onset vascular diseases in the Japanese population]
Vascular Diseases
[Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism in ischemic vascular disease]
Vascular Diseases
[Polymorphism of the methylenetetrahydrofolate reductase gene (MTHFR) and incidence of hyperhomocysteinemia-related diseases]
Vascular Diseases
[Polymorphisms in cystathionine beta-synthase and methylenetetrahydrofolate reductase genes as risk factors for cerebral vascular disease]
Vascular Diseases
[Vascular diseases, spina bifida and schizophrenia in a single family associated with the heterozygote mutation of the heat-sensitive variant of methylenetetrahydrofolate reductase]
Vasculitis
Co-existence of renovascular hypertension, polyarteritis nodosa, antiphospholipid syndrome and methylenetetrahydrofolate reductase mutation.
Vasculitis
Prediction of features of the course of chronic hepatitis C using Bayesian networks.
Venous Thromboembolism
A case control study on the contribution of factor V-Leiden, prothrombin G20210A, and MTHFR C677T mutations to the genetic susceptibility of deep venous thrombosis.
Venous Thromboembolism
ACMG Practice Guideline: lack of evidence for MTHFR polymorphism testing.
Venous Thromboembolism
Association between MTHFR C677T polymorphism and venous thromboembolism risk in the Chinese population: a meta-analysis of 24 case-controlled studies.
Venous Thromboembolism
Association of MTHFR genetic polymorphisms with venous thromboembolism in Uyghur population in Xinjiang, China.
Venous Thromboembolism
Association of Mycobacterium infections in patients with Mendelian susceptibility to mycobacterial disease with venous thromboembolism.
Venous Thromboembolism
C677T methylenetetrahydrofolate reductase gene polymorphism as a risk factor involved in venous thromboembolism: a population-based case-control study.
Venous Thromboembolism
C677T substitution in the methylenetetrahydrofolate reductase gene as a risk factor for venous thrombosis and arterial disease in selected patients.
Venous Thromboembolism
Combined Effect of MTHFR C677T and PAI-1 4G/5G Polymorphisms on the Risk of Venous Thromboembolism in Chinese Lung Cancer Patients.
Venous Thromboembolism
Common C677T polymorphism of the methylenetetrahydrofolate reductase gene and the risk of venous thromboembolism: meta-analysis of 31 studies.
Venous Thromboembolism
Correlations between methylenetetrahydrofolate reductase gene polymorphisms and venous thromboembolism: A meta-analysis of 99 genetic association studies.
Venous Thromboembolism
Factor V G1691A, prothrombin G20210A, and methylenetetrahydrofolate reductase [MTHFR] C677T gene polymorphism in angiographically documented coronary artery disease.
Venous Thromboembolism
Factor V Leiden, prothrombin 20210G --> A, methylenetetrahydrofolate reductase 677C --> T and plasminogen activator inhibitor 4G/5G polymorphism in women with pregnancy-related venous thromboembolism.
Venous Thromboembolism
Factor V Leiden, prothrombin G20210A, and methylenetetrahydrofolate reductase C677T mutations are not associated with chronic limb ischemia: the Linz Peripheral Arterial Disease (LIPAD) study.
Venous Thromboembolism
Genetic polymorphism of methylenetetrahydrofolate reductase and venous thromboembolism: a case-control study.
Venous Thromboembolism
Genetic polymorphisms associated with acute pulmonary embolism and deep venous thrombosis.
Venous Thromboembolism
Genetic susceptibility to pregnancy-related venous thromboembolism: roles of factor V Leiden, prothrombin G20210A, and methylenetetrahydrofolate reductase C677T mutations.
Venous Thromboembolism
High prevalence of three prothrombotic polymorphisms among Palestinians: factor V G1691A, factor II G20210A and methylenetetrahydrofolate reductase C677T.
Venous Thromboembolism
Homozygous methylentetrahydrofolate reductase C667T genotype anticipates age at venous thromboembolism by one decade.
Venous Thromboembolism
Hyperhomocysteinemia increases the risk of venous thrombosis independent of the C677T mutation of the methylenetetrahydrofolate reductase gene in selected Brazilian patients.
Venous Thromboembolism
Impact of inherited thrombophilia on the risk of recurrent venous thromboembolism onset in georgian population.
Venous Thromboembolism
Inherited and acquired thrombophilias and poor pregnancy outcome: should we be treating with heparin?
Venous Thromboembolism
Interaction between hyperhomocysteinemia and inherited thrombophilic factors in venous thromboembolism.
Venous Thromboembolism
Is genetic screening necessary for determining the possibility of venous thromboembolism in cancer patients?
Venous Thromboembolism
Lack of association between the C677T mutation in the 5,10-methylenetetrahydrofolate reductase gene and venous thromboembolism in Northwestern Greece.
Venous Thromboembolism
Massive Pulmonary Embolism Associated With Factor V Leiden, Prothrombin, and Methylenetetrahydrofolate Reductase Gene Mutations in a Young Patient on Oral Contraceptive Pills: A Case Report.
Venous Thromboembolism
Meta-analysis of the relationship between methylenetetrahydrofolate reductase C677T and A1298C polymorphism and venous thromboembolism in the Caucasian and Asian.
Venous Thromboembolism
Methionine synthase A2756G and methylenetetrahydrofolate reductase A1298C polymorphisms are not risk factors for idiopathic venous thromboembolism.
Venous Thromboembolism
Methylenetetrahydrofolate reductase polymorphism (C677T), hyperhomocysteinemia, and risk of ischemic cardiovascular disease and venous thromboembolism: prospective and case-control studies from the Copenhagen City Heart Study.
Venous Thromboembolism
MTHFR A1298C and C677T Polymorphisms Are Associated with Increased Risk of Venous Thromboembolism: A Retrospective Chart Review Study.
Venous Thromboembolism
No association of factor V Leiden, prothrombin G20210A, and MTHFR C677T gene polymorphisms with kidney allograft survival: a multicenter study.
Venous Thromboembolism
Plasma homocysteine level and 677C-->T mutation on the MTHFR gene in patients with venous thromboembolism.
Venous Thromboembolism
Prevalence of MTHFR C677T Single Nucleotide Polymorphism in Genetically Isolated Populations in Jordan.
Venous Thromboembolism
Prothrombin 20210 G-->A, MTHFR C677T mutations in women with venous thromboembolism associated with pregnancy.
Venous Thromboembolism
Prothrombotic risk factors in children with spontaneous venous thrombosis and their asymptomatic parents: a family study.
Venous Thromboembolism
Role of soluble P-selectin and methylenetetrahydrofolate reductase gene polymorphisms (677C>T) in Egyptian patients with venous thromboembolism.
Venous Thromboembolism
The 677C>T Mutation of the MTHFR Gene Increases the Risk of Venous Thromboembolism in Koreans and a Meta-Analysis From Asian Population.
Venous Thromboembolism
The importance of homozygous polymorphisms of methylenetetrahydrofolate reductase gene in romanian patients with idiopathic venous thromboembolism.
Venous Thromboembolism
The Methylenetetrahydrofolate Reductase Polymorphism (MTHFR c.677C>T) and Elevated Plasma Homocysteine Levels in a U.S. Pediatric Population with Incident Thromboembolism.
Venous Thromboembolism
The prevalence of Factor V Leiden, prothrombin G20210A, MTHFR C677T and MTHFR A1298C mutations in healthy Turkish population.
Venous Thromboembolism
The VITA project: C677T mutation in the methylene-tetrahydrofolate reductase gene and risk of venous thromboembolism.
Venous Thromboembolism
Thrombophilia and venous thromboembolism in pregnancy: a meta-analysis of genetic risk.
Venous Thromboembolism
Thrombotic events revisited in children with acute lymphoblastic leukemia: impact of concomitant Escherichia coli asparaginase/prednisone administration.
Venous Thromboembolism
Thyroid vein thrombosis in a young woman with methylenetetrahydrofolate reductase gene mutation receiving cyproterone acetate/ethinylestradiol treatment for polycystic ovary syndrome: a case report.
Venous Thromboembolism
Venous thromboembolism associated with hyperhomocysteinemia, homozygosity for the methylenetetrahydrofolate reductase 677C>T gene variant, and secondary polycythemia.
Venous Thromboembolism
Venous thromboembolism during pregnancy is not associated with persistent elevated activated protein C (APC) sensitivity ratio based on the endogenous thrombin potential.
Venous Thromboembolism
Venous thromboembolism, factor V Leiden, and methylenetetrahydrofolate reductase in a sickle cell anemia patient.
Venous Thromboembolism
[Association between gene polymorphisms of methylenetetrahydrofolate reductase and plasma homocysteine in Uygur patients with venous thromboembolism].
Venous Thromboembolism
[Effect of hyperhomocysteinemia and methylenetetrahydrofolate reductase 677C --> T mutation in venous thromboembolism risk of young adults]
Venous Thromboembolism
[Lowering high levels of fasting total homocysteine with folic acid and vitamins B in patients with venous thromboembolism: relationship between response and the C677T methylenetetrahydrofolate reductase (MTHRF) genotype]
Venous Thromboembolism
[Relationship of plasma homocysteine and folic acid levels and 5,10-methylenetetrahydrofolate reductase gene mutation with venous thromboembolism]
Venous Thromboembolism
[Venous thromboembolism in a young patient. Diagnosis: Retinal vein thromboembolism in mutation of the methylenetetrahydrofolate reductase gene]
Venous Thrombosis
A 17-year-old male with pseudotumor cerebri secondary to performance-enhancing steroids triggering venous thrombosis in the brain.
Venous Thrombosis
A boy with venous thrombosis, homozygous for factor V Leiden, prothrombin G20210A and MTHFR C667t mutations, but belonging to an asymptomatic family.
Venous Thrombosis
A case control study on the contribution of factor V-Leiden, prothrombin G20210A, and MTHFR C677T mutations to the genetic susceptibility of deep venous thrombosis.
Venous Thrombosis
A common mutation in the methylenetetrahydrofolate reductase gene (C677T) increases the risk for deep-vein thrombosis in patients with mutant factor V (factor V:Q506).
Venous Thrombosis
A second mutation in the methylenetetrahydrofolate reductase gene and the risk of venous thrombotic disease.
Venous Thrombosis
Abdominal venous thrombosis in neonates and infants: role of prothrombotic risk factors - a multicentre case-control study. For the Childhood Thrombophilia Study Group.
Venous Thrombosis
Adaptive developmental plasticity in methylene tetrahydrofolate reductase (MTHFR) C677T polymorphism limits its frequency in South Indians.
Venous Thrombosis
An unfavorable combination of Factor V Leiden with age, weight, and blood group causes high risk of pregnancy-associated venous thrombosis: a population-based nested case-control study.
Venous Thrombosis
Arterial thrombosis associated with factor V Leiden and methylenetetrahydrofolate reductase C677T mutation in childhood membranous glomerulonephritis.
Venous Thrombosis
Association between polymorphism of MTHFR c.677C>T and risk of cardiovascular disease in Turkish population: a meta-analysis for 2.780 cases and 3.022 controls.
Venous Thrombosis
Association of methylenetetrahydrofolate reductase (MTHFR-677 and MTHFR-1298) genetic polymorphisms with occlusive artery disease and deep venous thrombosis in Macedonians.
Venous Thrombosis
Association of Methylenetetrahydrofolate Reductase C677T Polymorphism with Hyperhomocysteinemia and Deep Vein Thrombosis in the Iranian Population.
Venous Thrombosis
Association study of methylenetetrahydrofolate reductase A1298C mutation with cerebral venous thrombosis risk in an Iranian population.
Venous Thrombosis
Association study of methylenetetrahydrofolate reductase C677T mutation with cerebral venous thrombosis in an Iranian population.
Venous Thrombosis
C677T substitution in the methylenetetrahydrofolate reductase gene as a risk factor for venous thrombosis and arterial disease in selected patients.
Venous Thrombosis
CBS 844ins68, MTHFR TT677 and EPCR 4031ins23 genotypes in patients with deep-vein thrombosis.
Venous Thrombosis
Cerebral sinovenous thrombosis associated with factor V Leiden and methylenetetrahydrofolate reductase A1298C mutation in adult membranous glomerulonephritis.
Venous Thrombosis
Cerebral sinus venous thrombosis in a subject with thyrotoxicosis and MTHFR gene polymorphism.
Venous Thrombosis
Cerebral Venous Thrombosis and Livedo Reticularis in a Case with MTHFR 677TT Homozygote.
Venous Thrombosis
Clinical Implications of Methylenetetrahydrofolate Reductase Mutations and Plasma Homocysteine Levels in Patients with Thromboembolic Occlusion.
Venous Thrombosis
Coexistence of left-sided inferior vena cava, deep vein thrombosis of the upper and lower extremities and prothrombotic polymorphisms in a young patient: a case report.
Venous Thrombosis
Common C677T polymorphism in the methylenetetrahydrofolate reductase gene increases the risk for deep vein thrombosis in patients with predisposition of thrombophilia.
Venous Thrombosis
Contraception-related deep venous thrombosis and pulmonary embolism in a 17-Year-old girl heterozygous for factor V leiden, prothrombin G20210A mutation, MTHFR C677T and homozygous for PAI-1 mutation: report of a family with multiple genetic risk factors and review of the literature.
Venous Thrombosis
Correlations between methylenetetrahydrofolate reductase gene polymorphisms and venous thromboembolism: A meta-analysis of 99 genetic association studies.
Venous Thrombosis
Deep vein thrombosis after orthopedic surgery in a patient with type 1 von Willebrand disease and mutations in the MTHFR and beta-fibrinogen genes.
Venous Thrombosis
Deep venous thrombosis and thrombophilic mutations in western Iran: association with factor V Leiden.
Venous Thrombosis
Deletion polymorphism in the angiotensin-converting enzyme gene as a thrombophilic risk factor after hip arthroplasty.
Venous Thrombosis
Detection of genomic polymorphisms associated with venous thrombosis using the invader biplex assay.
Venous Thrombosis
Easy, accurate and reliable screening for SNPs by ion pair/reverse phase HPLC: simultaneous detection of factor V G1691A, prothrombin G20210A and methylenetetrahydrofolate reductase C677T variants.
Venous Thrombosis
Effect of methylenetetrahydrofolate reductase 677 C-T, 1298 A-C, and 1317 T-C on factor V 1691 mutation in Turkish deep vein thrombosis patients.
Venous Thrombosis
Endocrine treatment of male-to-female transsexuals using gonadotropin-releasing hormone agonist.
Venous Thrombosis
Evaluation of electronic microarrays for genotyping factor V, factor II, and MTHFR.
Venous Thrombosis
Factor V Leiden, prothrombin 20210A, methylenetetrahydrofolate reductase 677T, and population genetics.
Venous Thrombosis
Frequency and association of 1691 (G>A) FVL, 20210 (G>A) PT and 677 (C>T) MTHFR with deep vein thrombosis in the population of Bosnia and Herzegovina.
Venous Thrombosis
Genetic determinants of heritable venous thrombosis: genotyping methods for factor V(Leiden)A1691G, methylenetetrahydrofolate reductase C677T, prothrombin G20210A mutation, and algorithms for venous thrombosis investigations.
Venous Thrombosis
Genetic factors associated with thrombosis in pregnancy in a United States population.
Venous Thrombosis
Genetic polymorphisms and risk of recurrent deep venous thrombosis in young people: prospective cohort study.
Venous Thrombosis
Genetic variations observed in arterial and venous thromboembolism--relevance for therapy, risk prevention and prognosis.
Venous Thrombosis
High prevalence of factor V Leiden and prothrombin G20101A mutations in Kashmiri patients with venous thromboembolism.
Venous Thrombosis
High prevalence of thrombophilic genotypes in patients with acute mesenteric vein thrombosis.
Venous Thrombosis
Homocysteine, MTHFR and risk of venous thrombosis: a meta-analysis of published epidemiological studies.
Venous Thrombosis
Homozygous cystathionine beta-synthase deficiency, combined with factor V Leiden or thermolabile methylenetetrahydrofolate reductase in the risk of venous thrombosis.
Venous Thrombosis
Hyperhomocysteinemia and of Methylenetetrahydrofolate Reductase (C677T) Genetic Polymorphism in Patients with Deep Vein Thrombosis.
Venous Thrombosis
Hyperhomocysteinemia increases the risk of venous thrombosis independent of the C677T mutation of the methylenetetrahydrofolate reductase gene in selected Brazilian patients.
Venous Thrombosis
Hyperhomocysteinemia, deep vein thrombosis and vitamin B12 deficiency in a metformin-treated diabetic patient.
Venous Thrombosis
Hyperhomocysteinemia: clinical and therapeutical involvement in venous thrombosis.
Venous Thrombosis
Improved real-time multiplex polymerase chain reaction detection of methylenetetrahydrofolate reductase (MTHFR) 677C>T and 1298A>C polymorphisms using nearest neighbor model-based probe design.
Venous Thrombosis
Influence of Amerindian mitochondrial DNA haplogroups on thrombosis susceptibility and frequency of four genetic prothrombotic variants in Southern Chilean subjects.
Venous Thrombosis
Inherited coagulation disorders in cirrhotic patients with portal vein thrombosis.
Venous Thrombosis
Inherited Thrombophilia in a Lebanese Family of Four Generations: A Case Report of Recurrent Miscarriage.
Venous Thrombosis
Interactions among methylenetetrahydrofolate reductase (MTHFR) and cystathionine ?-synthase (CBS) polymorphisms - a cross-sectional study: multiple heterozygosis as a risk factor for higher homocysteine levels and vaso-occlusive episodes.
Venous Thrombosis
Livedoid vasculopathy and hypercoagulability in a patient with primary Sjögren's syndrome.
Venous Thrombosis
Low folate levels and thermolabile methylenetetrahydrofolate reductase as primary determinant of mild hyperhomocystinemia in normal and thromboembolic subjects.
Venous Thrombosis
Lupus anticoagulant, factor V Leiden, and methylenetetrahydrofolate reductase gene mutation in a lupus patient with cerebral venous thrombosis.
Venous Thrombosis
Major and potential prothrombotic genotypes in patients with venous thrombosis and in healthy subjects from Slovenia.
Venous Thrombosis
Management of hereditary angioedema type I and homozygous MTHFR mutation during pregnancy.
Venous Thrombosis
Methylenetetrahydrofolate reductase (MTHFR-677 and MTHFR-1298) genotypes and haplotypes and plasma homocysteine levels in patients with occlusive artery disease and deep venous thrombosis.
Venous Thrombosis
Methylenetetrahydrofolate reductase C677T polymorphism, venous thrombosis, cardiovascular risk, and other effects.
Venous Thrombosis
Methylenetetrahydrofolate Reductase Gene Polymorphism (C677T) as a Risk Factor for Arterial Thrombosis in Georgian Patients.
Venous Thrombosis
Methylenetetrahydrofolate reductase polymorphism in healthy volunteers and its correlation with homocysteine levels in patients with thrombosis.
Venous Thrombosis
Mild hyperhomocysteinemia and MTHFR C677T do not increase the risk for venous thrombosis in a Spanish population.
Venous Thrombosis
Molecular Analysis of Prothrombotic Gene Variants in Venous Thrombosis: A Potential Role for Sex and Thrombotic Localization.
Venous Thrombosis
MTHFR C677T polymorphism and its relation to ischemic stroke in the Black Sea Turkish population.
Venous Thrombosis
Mutations in coagulation factors in women with unexplained late fetal loss.
Venous Thrombosis
Myocardial infarction and venous thrombosis in a 42-year old woman with heterozygous methylenetetrahydrofolate reductase (MTHRF) gene mutation, hyperhomocysteinemia, and protein C deficiency.
Venous Thrombosis
No association between the common MTHFR 677C->T polymorphism and venous thrombosis: results from the MEGA study.
Venous Thrombosis
No evidence for an increased risk of venous thrombosis in patients with factor V Leiden by the homozygous 677 C to T mutation in the methylenetetrahydrofolate-reductase gene.
Venous Thrombosis
No interaction between factor V Leiden and hyperhomocysteinemia or MTHFR 677TT genotype in venous thrombosis. Results of a meta-analysis of published studies and a large case-only study.
Venous Thrombosis
PAI-1 4G÷5G and MTHFR C677T polymorphisms increased the accuracy of two prediction scores for the risk of acute lower extremity deep vein thrombosis.
Venous Thrombosis
Possible Association Between the Methylenetetrahydrofolate Reductase Gene C677T Polymorphism and Preexisting Portal Vein Thrombosis in Liver Transplant Recipients.
Venous Thrombosis
Prevalence of factor V Leiden, FII G20210A, FXIII Val34Leu and MTHFR C677T polymorphisms in cancer patients with and without venous thrombosis.
Venous Thrombosis
Prevalence of factor V leiden, MTHFR C677T and MTHFR A1298C polymorphisms in patients with deep vein thrombosis in Central Iran.
Venous Thrombosis
Prevalence of genetic markers for thrombophilia in recurrent pregnancy loss.
Venous Thrombosis
Prevalence of genetic prothrombotic risk factors: 1691G > A FV, 20210G > A PT and 677C > T MTHFR mutations in the Bosnian population.
Venous Thrombosis
Prevalence of hyperhomocysteinemia and the MTHFR C677T polymorphism in patients with arterial and venous thrombosis from North Western Russia.
Venous Thrombosis
Prevalence of methylenetetrahydrofolate reductase C677T and its association with arterial and venous thrombosis in the Chinese population.
Venous Thrombosis
Prevalence of methylenetetrahydrofolate reductase mutations in patients with venous thrombosis.
Venous Thrombosis
Prevalence of prothrombin 20210A allele and methylenetetrahydrofolate reductase C677T genetic mutations in the Chinese population.
Venous Thrombosis
Prevalence of prothrombin G20210A, factor V G1691A (Leiden), and methylenetetrahydrofolate reductase (MTHFR) C677T in seven different populations determined by multiplex allele-specific PCR.
Venous Thrombosis
Prevalence of thrombophilic mutations in patients with unprovoked thromboembolic disease. A comparative analysis regarding arterial and venous disease.
Venous Thrombosis
Prospective study of homocysteine and MTHFR 677TT genotype and risk for venous thrombosis in a general population--results from the HUNT 2 study.
Venous Thrombosis
Prothrombin 20210 G-->A, MTHFR C677T mutations in women with venous thromboembolism associated with pregnancy.
Venous Thrombosis
Prothrombotic inherited abnormalities other than factor V Leiden mutation do not play a role in venous thrombosis in inflammatory bowel disease.
Venous Thrombosis
Recurrent cerebral venous thrombosis associated with heterozygote methylenetetrahydrofolate reductase C677T mutation and sickle cell trait without homocysteinemia: an autopsy case report and review of literature.
Venous Thrombosis
Relation of three genetic traits to venous thrombosis in an African-American population.
Venous Thrombosis
Relationship between genetic polymorphism of MTHFR C677T and lower extremities deep venous thrombosis.
Venous Thrombosis
Risk of Venous Thrombosis in Carriers of a Common Mutation in the Homocysteine Regulatory Enzyme Methylenetetrahydrofolate Reductase.
Venous Thrombosis
Role of methylenetetrahydrofolate reductase A1298C polymorphism in cerebral venous thrombosis.
Venous Thrombosis
Subacute methotrexate neurotoxicity and cerebral venous sinus thrombosis in a 12-year-old with acute lymphoblastic leukemia and methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism: homocysteine-mediated methotrexate neurotoxicity via direct endothelial injury.
Venous Thrombosis
The 677T genotype of the common MTHFR thermolabile variant and fasting homocysteine in childhood venous thrombosis.
Venous Thrombosis
The C677T mutation of the methylenetetrahydrofolate reductase gene is not associated with the risk of coronary artery disease or venous thrombosis among Chinese in Taiwan.
Venous Thrombosis
The dose-response relation between serum homocysteine and cardiovascular disease: implications for treatment and screening.
Venous Thrombosis
The G1691 --> A mutation of factor V, but not the G20210 --> A mutation of factor II or the C677 --> T mutation of methylenetetrahydrofolate reductase genes, is associated with venous thrombosis in patients with lupus anticoagulants.
Venous Thrombosis
The G20210A mutation of the prothrombin gene in patients with previous first episodes of deep-vein thrombosis: prevalence and association with factor V G1691A, methylenetetrahydrofolate reductase C677T and plasma prothrombin levels.
Venous Thrombosis
The methylenetetrahydrofolate reductase TT677 genotype is associated with venous thrombosis independently of the coexistence of the FV Leiden and the prothrombin A20210 mutation.
Venous Thrombosis
The MTHFR 677TT and 677CT/1298AC genotypes in Cypriot patients may be predisposing to hypertensive nephrosclerosis and chronic renal failure.
Venous Thrombosis
The prevalence of C677T mutation in the methylenetetrahydrofolate reductase gene and its association with venous thrombophilia in Taiwanese Chinese.
Venous Thrombosis
The prevalence of factor V (G1691A), MTHFR (C677T) and PT (G20210A) gene mutations in arterial thrombosis.
Venous Thrombosis
The role of genetics in coronary artery bypass surgery patients under 30 years of age.
Venous Thrombosis
The role of point mutations in the genes, predisposing inherited thrombophilia in the pathogeneses of proximal and distal deep vein thrombosis in georgian population.
Venous Thrombosis
Thermolabile methylenetetrahydrofolate reductase and factor V Leiden in the risk of deep-vein thrombosis.
Venous Thrombosis
Thrombophilic polymorphisms - factor V Leiden G1691A, prothrombin G20210A and MTHFR C677T - in Tunisian patients with cerebral venous thrombosis.
Venous Thrombosis
Thrombophilic predisposition in stroke and venous thromboembolism in Danish patients.
Venous Thrombosis
Venous thromboembolism, factor V Leiden, and methylenetetrahydrofolate reductase in a sickle cell anemia patient.
Venous Thrombosis
[A common mutation C677T in the 5,10-methyltetrahydrofolate reductase gene is associated to idiopathic deep venous thrombosis]
Venous Thrombosis
[Antiphospholipid syndrome in the structure of hematogenic thrombophilia in young and middle-aged patients with venous thrombosis]
Venous Thrombosis
[C677T mutation in methylentetrahydrofolatereductase gene in patients with venous thromboses from the central region of Russia correlates with a high risk of pulmonary artery thromboembolism]
Venous Thrombosis
[Factor V Leiden, FII G20210A, MTHFR C677T mutations as risk factors for venous thrombosis during pregnancy and puerperium]
Venous Thrombosis
[Homocysteine levels and polymorphisms of MTHFR and CBS genes in Colombian patients with superficial and deep venous thrombosis]
Venous Thrombosis
[Homocysteine, 5,10-methylenetetrahydrofolate reductase and deep venous thrombosis. Survey of 120 patients in internal medicine]
Venous Thrombosis
[Study on the association of polymorphisms in homocysteine metabolism related enzymes with deep venous thrombosis]
Venous Thrombosis
[The C677T mutation in the methylenetetrahydrofolate reductase gene and its association with deep vein thrombophilia in Shandong Hans]
Vertebral Artery Dissection
Spontaneous Bilateral Vertebral Artery Dissection Secondary to PAI-1, MTHFR C677T and ACE Gene Mutations in a Young Man.
Virus Diseases
Lack of association between methylenetetrahydrofolate reductase C677T polymorphism, HPV infection and cervical intraepithelial neoplasia in Brazilian women.
Virus Diseases
The effect of methylenetetrahydrofolate reductase polymorphisms on susceptibility to human papilloma virus infection and cervical cancer.
Vitamin B 12 Deficiency
Association between MTHFR 677C>T Polymorphism and Vitamin B12 Deficiency: A Case-control Study.
Vitamin B 12 Deficiency
Association between the MTHFR C677T polymorphism, blood folate and vitamin B12 deficiency, and elevated serum total homocysteine in healthy individuals in Yunnan Province, China.
Vitamin B 12 Deficiency
Association of Vitamin B12 Deficiency with Homozygosity of the TT MTHFR C677T Genotype, Hyperhomocysteinemia, and Endothelial Cell Dysfunction.
Vitamin B 12 Deficiency
Folate, folic acid and 5-methyltetrahydrofolate are not the same thing.
Vitamin B 12 Deficiency
Hemolysis and hyperhomocysteinemia caused by cobalamin deficiency: three case reports and review of the literature.
Vitamin B 12 Deficiency
High frequency of vitamin B12 deficiency in asymptomatic individuals homozygous to MTHFR C677T mutation is associated with endothelial dysfunction and homocysteinemia.
Vitamin B 12 Deficiency
Homocysteine, methylenetetrahydrofolate reductase C677T polymorphism and the B-vitamins: a facet of nature-nurture interplay.
Vitamin B 12 Deficiency
Hyperhomocysteinaemia, folate and vitamin B12 in unsupplemented haemodialysis patients: effect of oral therapy with folic acid and vitamin B12.
Vitamin B 12 Deficiency
Hyperhomocysteinemia, deep vein thrombosis and vitamin B12 deficiency in a metformin-treated diabetic patient.
Vitamin B 12 Deficiency
Methylenetetrahydrofolate Reductase Gene-specific Methylation and Recurrent Miscarriages: A Case- Control Study from North India.
Vitamin B 12 Deficiency
Modulator Effects of the Methylenetetrahydrofolate Reductase C677T Polymorphism on Response to Vitamin B12 Therapy and Homocysteine Metabolism.
Vitamin B 12 Deficiency
MTHFR polymorphisms involved in vitamin B12 deficiency associated with atrophic gastritis.
Vitamin B 12 Deficiency
Recurrent stroke in a patient with vitamin B12 deficiency and MTHFR mutation.
Vitamin B 12 Deficiency
Severe atherosclerosis in rheumatoid arthritis and hyperhomocysteinemia: is there a link?
Vitamin B 12 Deficiency
Venous thromboembolism due to hyperhomocysteinaemia and tuberculosis.
Vitiligo
Association Between Methylenetetrahydrofolate Reductase Gene Polymorphisms and Risk of Vitiligo: A Systematic Review and Meta-Analysis.
Vitiligo
Association of elevated homocysteine levels and Methylenetetrahydrofolate reductase (MTHFR) 1298 A?>?C polymorphism with Vitiligo susceptibility in Gujarat.
Vitiligo
Association of MTHFR C677T polymorphism with elevated homocysteine level and disease development in vitiligo.
Vitiligo
Associations of methylenetetrahydrofolate reductase gene (MTHFR) rs1801131 and rs1801133 polymorphisms with susceptibility to vitiligo: A meta-analysis.
Vitiligo
Estimation of Homocysteine Level and Methylenetetrahydrofolate Reductase (MTHFR) Gene and Cystathionine B Synthase (CBS) Gene Polymorphisms in Vitiligo Patients.
Vitiligo
Evaluation of genotyping methods and costs for MTHFR, CBS and MTRR polymorphisms in patients with vitiligo.
Vitiligo
Genetic polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene and risk of vitiligo in Han Chinese populations: a genotype-phenotype correlation study.
Vitiligo
High incidence of MTHFR, CBS, and MTRR polymorphisms in vitiligo patients. Preliminary report in a retrospective study.
Vitiligo
Methylenetetrahydrofolate reductase (MTHFR): could it be a small piece in vitiligo jigsaw puzzle?
Vitiligo
Serum homocysteine, vitamin B12, folic acid levels and methylenetetrahydrofolate reductase (MTHFR) gene polymorphism in vitiligo.
von Willebrand Disease, Type 1
Deep vein thrombosis after orthopedic surgery in a patient with type 1 von Willebrand disease and mutations in the MTHFR and beta-fibrinogen genes.
von Willebrand Diseases
Deep vein thrombosis after orthopedic surgery in a patient with type 1 von Willebrand disease and mutations in the MTHFR and beta-fibrinogen genes.
Wilms Tumor
Impact of the MTHFR C677T polymorphism on risk of Wilms tumor: case-control study.
Wilms Tumor
RFC-1 80G>A Polymorphism in Case-Mother/Control-Mother Dyads Is Associated with Risk of Nephroblastoma and Neuroblastoma.
Xanthomatosis, Cerebrotendinous
Inborn Errors of Metabolism Associated With Autism Spectrum Disorders: Approaches to Intervention.
Xeroderma Pigmentosum
Pharmacogenetic profiling in patients with advanced colorectal cancer treated with first-line FOLFIRI chemotherapy.
Xeroderma Pigmentosum
Pharmacogenetic profiling in patients with advanced colorectal cancer treated with first-line FOLFOX-4 chemotherapy.
[methionine synthase] reductase deficiency
Defects in homocysteine metabolism: diversity among hyperhomocyst(e)inemias.
[pyruvate dehydrogenase (acetyl-transferring)]-phosphatase deficiency
Diagnostic yield of genetic testing in epileptic encephalopathy in childhood.
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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
0.123
5,10-methylenetetrahydropteroylglutamate
pH 8.0, 30°C, at saturating concentrations of NADP+ (6.0 mM)
0.133
5,10-methylenetetrahydropteroylglutamate
pH 8.0, 30°C, at saturating concentrations of NAD+ (1.0 mM)
0.302
5,10-methylenetetrahydropteroylpentaglutamate
pH 8.0, 30°C, at saturating concentrations of NADP+ (6.0 mM)
0.359
5,10-methylenetetrahydropteroylpentaglutamate
pH 8.0, 30°C, at saturating concentrations of NAD+ (1.0 mM)
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TURNOVER NUMBER [1/s]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
1.5
5,10-methylenetetrahydropteroylglutamate
pH 8.0, 30°C, at saturating concentrations of NADP+ (6.0 mM)
12.4
5,10-methylenetetrahydropteroylglutamate
pH 8.0, 30°C, at saturating concentrations of NAD+ (1.0 mM)
6.4
5,10-methylenetetrahydropteroylpentaglutamate
pH 8.0, 30°C, at saturating concentrations of NADP+ (6.0 mM)
15.4
5,10-methylenetetrahydropteroylpentaglutamate
pH 8.0, 30°C, at saturating concentrations of NAD+ (1.0 mM)
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kcat/KM VALUE [1/mMs-1]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
12
5,10-methylenetetrahydropteroylglutamate
pH 8.0, 30°C, at saturating concentrations of NADP+ (6.0 mM)
93
5,10-methylenetetrahydropteroylglutamate
pH 8.0, 30°C, at saturating concentrations of NAD+ (1.0 mM)
21
5,10-methylenetetrahydropteroylpentaglutamate
pH 8.0, 30°C, at saturating concentrations of NADP+ (6.0 mM)
43
5,10-methylenetetrahydropteroylpentaglutamate
pH 8.0, 30°C, at saturating concentrations of NAD+ (1.0 mM)
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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
0.0003
2.4
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ORGANISM
COMMENTARY
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
normal human fibroblasts MCH-39, EBV-transformed normal human lymphoblast lines TL3 and TL4, human tumor lines MNNG/HOS(TE85 clone F-5), MCF-7, CCRF-CEM, osteosarcoma MG-63(ATCC CRL 1427), human chronic myeolitic leukemia line K562, Burkitt lymphoma line Raji, human choriocarcinoma BeWo, human intestinal carcinoma HCT
-
-
brenda
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SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
SOURCE
both Mthfd2 and Mthfd2l are expressed during embryogenesis but differ in timing of expression. Mthfd2l expression is low in early developmental stages but begins to increase at embryonic day 10.5 and remains elevated through birth while Mthfd2 is expressed more abundantly during early developmental stages and begins to taper off, with little or no expression observed in most adult tissues
brenda
additional information
upregulation and overexpression in cancer cells
brenda
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LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY
GeneOntology No.
LITERATURE
SOURCE
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GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
metabolism
metabolism
the enzyme is involved in folate pathway. It is involved in mitochondrial NADPH production. It is proposed that isoenzyme MTHFD2 may be expressed to boost flux through the mitochondrial folate pathway during early periods of embryogenesis when isoenzyme MTHFD2L alone is not sufficient to support high rates of cell proliferation
metabolism
the mitochondrial methylenetetrahydrofolate dehydrogenase/cyclohydrolase(MTHFD2)-controlled cluster redirects metabolism to glycine synthesis to replenish purine nucleotides. Since endothelial cells secrete purines in response to oxPAPC, the MTHFD2-controlled response maintains endothelial ATP. Accordingly, MTHFD2-dependent glycine synthesis is a prerequisite for angiogenesis. It is proposed that endothelial cells undergo MTHFD2-mediated reprogramming toward serine-glycine and mitochondrial one-carbon metabolism to compensate for the loss of ATP in response to oxidized phospholipids during atherosclerosis
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UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION
The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable).
The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable). MTD2L_HUMAN
347
0
37315
Swiss-Prot
Mitochondrion (Reliability: 1)
MTDC_HUMAN
350
0
37895
Swiss-Prot
Mitochondrion (Reliability: 2)
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PDB
SCOP
CATH
UNIPROT
ORGANISM
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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
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CRYSTALLIZATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
crystal structure of the enzyme (MTHFD2) in complex with a substrate-based inhibitor and the enzyme cofactors NAD+ and inorganic phosphate
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PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
C677T
-
one of several polymorphisms, leads to increased risk of hepatocellular carcinoma in patients with alcoholic cirrhosis, determination of genotypes in liver transplant patients with cirrhosis with and without hepatocellular carcinoma and in healthy persons
D133A
cosubstrate NAD+, 1.7% of wild-type activity, cosubstrate NADP+, 5.5% of wild-type activity
D133N
cosubstrate NAD+, 20.4% of wild-type activity, cosubstrate NADP+, 82.2% of wild-type activity
D133S
cosubstrate NAD+, 17.8% of wild-type activity, cosubstrate NADP+, 34.5% of wild-type activity
R198A
cosubstrate NAD+, 0.7% of wild-type activity, cosubstrate NADP+, 5.3% of wild-type activity
R198K
cosubstrate NAD+, 56% of wild-type activity, cosubstrate NADP+, 42% of wild-type activity
R198S
cosubstrate NAD+, 0.9% of wild-type activity, cosubstrate NADP+, 53% of wild-type activity
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STORAGE STABILITY
ORGANISM
UNIPROT
LITERATURE
-80°C, enzyme is stable in 20-30% glycerol buffer and can be frozen for months without loss of activity
-
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PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
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EXPRESSION
ORGANISM
UNIPROT
LITERATURE
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APPLICATION
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Mejia, N.; Mackenzie, R.E.
NAD-dependent methylenetetrahydrofolate dehydrogenase is expressed by immortal cells
J. Biol. Chem.
260
14616-14620
1985
Cricetulus griseus, Cricetus cricetus, Homo sapiens, Mesocricetus auratus, Mus musculus, Rattus norvegicus
brenda
Mackenzie, R.E.; Mejia, N.; Yang, X.M.
Methylenetetrahydrofolate dehydrogenases in normal and transformed mammalian cells
Adv. Enzyme Regul.
27
31-39
1988
Saccharomyces cerevisiae, Homo sapiens, Mus musculus
brenda
Barlowe, C.K.; Appling, D.R.
Isolation and characterization of a novel eukaryotic monofunctional NAD+-dependent 5,10-methylenetetrahydrofolate dehydrogenase
Biochemistry
29
7089-7094
1990
Acetobacterium woodii, Saccharomyces cerevisiae, Clostridium formicaceticum, Homo sapiens, Rattus norvegicus, Saccharomyces cerevisiae KSY8
brenda
Smith, G.K.; Banks, S.D.; Monaco, T.J.; Rigual, R.; Duch, D.S.; Mullin, R.J.; Huber, B.E.
Activity of an NAD-dependent 5,10-methylenetetrahydrofolate dehydrogenase in normal tissue, neoplastic cells, and oncogene-transformed cells
Arch. Biochem. Biophys.
283
367-371
1990
Bos taurus, Homo sapiens, Mus musculus, Rattus norvegicus, Rattus norvegicus Fischer
brenda
Peri, K.G.; Mackenzie, R.E.
NAD(+)-dependent methylenetetrahydrofolate dehydrogenase-cyclohydrolase: detection of the mRNA in normal murine tissues and transcriptional regulation of the gene in cell lines
Biochim. Biophys. Acta
1171
281-287
1993
Homo sapiens, Mus musculus, Rattus norvegicus
brenda
Price, B.D.; Laughon, A.
The isolation and characterization of a Drosophila gene encoding a putative NAD-dependent methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase
Biochim. Biophys. Acta
1173
94-98
1993
Drosophila melanogaster, Homo sapiens, Mus musculus
brenda
Yang, X.M.; Mackenzie, R.E.
NAD-dependent methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase is the mammalian homolog of the mitochondrial enzyme encoded by the yeast MIS1 gene
Biochemistry
32
11118-11123
1993
Saccharomyces cerevisiae, Homo sapiens, Mus musculus
brenda
Tremblay, G.B.; Sohi, S.S.; Retnakaran, A.; Mackenzie, R.E.
NAD-dependent methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase is targeted to the cytoplasm in insect cell lines
FEBS Lett.
368
177-182
1995
Antheraea eucalypti, Choristoneura fumiferana, Drosophila melanogaster, Homo sapiens, Malacosoma disstria, Mus musculus, Spodoptera frugiperda
brenda
Appling, D.R.; West, M.G.
Monofunctional NAD-dependent 5,10-methylenetetrahydrofolate dehydrogenase from Saccharomyces cerevisiae
Methods Enzymol.
281
178-188
1997
Acetobacterium woodii, Saccharomyces cerevisiae, Clostridium formicaceticum, Drosophila melanogaster, Homo sapiens, Mus musculus
brenda
Mackenzie, R.E.
Mitochondrial NAD-dependent methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase
Methods Enzymol.
281
171-177
1997
Saccharomyces cerevisiae, Drosophila melanogaster, Homo sapiens, Mus musculus, Spodoptera frugiperda
brenda
Patel, H.; Christensen, K.E.; Mejia, N.; Mackenzie, R.E.
Mammalian mitochondrial methylenetetrahydrofolate dehydrogenase-cyclohydrolase
Arch. Biochem. Biophys.
403
145-148
2002
Drosophila melanogaster, Homo sapiens, Mus musculus
brenda
Saffroy, R.; Pham, P.; Chiappini, F.; Gross-Goupil, M.; Castera, L.; Azoulay, D.; Barrier, A.; Samuel, D.; Debuire, B.; Lemoine, A.
The MTHFR 677C > T polymorphism is associated with an increased risk of hepatocellular carcinoma in patients with alcoholic cirrhosis
Carcinogenesis
25
1443-1448
2004
Homo sapiens
brenda
Christensen, K.E.; Mirza, I.A.; Berghuis, A.M.; Mackenzie, R.E.
Magnesium and phosphate ions enable NAD binding to methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase
J. Biol. Chem.
280
34316-34323
2005
Homo sapiens (P13995), Homo sapiens
brenda
Shin, M.; Momb, J.; Appling, D.R.
Human mitochondrial MTHFD2 is a dual redox cofactor-specific methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase
Cancer Metab.
5
11
2017
Homo sapiens (P13995), Homo sapiens (Q9H903)
brenda
Gustafsson, R.; Jemth, A.S.; Gustafsson, N.M.; Faernegardh, K.; Loseva, O.; Wiita, E.; Bonagas, N.; Dahllund, L.; Llona-Minguez, S.; Haeggblad, M.; Henriksson, M.; Andersson, Y.; Homan, E.; Helleday, T.; Stenmark, P.
Crystal structure of the emerging cancer target MTHFD2 in complex with a substrate-based inhibitor
Cancer Res.
77
937-948
2017
Homo sapiens (P13995)
brenda
Hitzel, J.; Lee, E.; Zhang, Y.; Bibli, S.I.; Li, X.; Zukunft, S.; Pflueger, B.; Hu, J.; Schuermann, C.; Vasconez, A.E.; Oo, J.A.; Kratzer, A.; Kumar, S.; Rezende, F.; Josipovic, I.; Thomas, D.; Giral, H.; Schreiber, Y.; Geisslinger, G.; Fork, C.; Yang, X.; Sigala, F.; Romanoski, C.E.; Kroll, J.; Jo, H.; Lan, L.a.n.d.
Oxidized phospholipids regulate amino acid metabolism through MTHFD2 to facilitate nucleotide release in endothelial cells
Nat. Commun.
9
2292
2018
Homo sapiens (P13995)
brenda
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