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Information on EC 1.4.3.16 - L-aspartate oxidase and Organism(s) Pseudomonas aeruginosa

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EC Tree
     1 Oxidoreductases
         1.4 Acting on the CH-NH2 group of donors
             1.4.3 With oxygen as acceptor
                1.4.3.16 L-aspartate oxidase
IUBMB Comments
A flavoprotein (FAD). L-Aspartate oxidase catalyses the first step in the de novo biosynthesis of NAD+ in some bacteria. O2 can be replaced by fumarate as electron acceptor, yielding succinate . The ability of the enzyme to use both O2 and fumarate in cofactor reoxidation enables it to function under both aerobic and anaerobic conditions . Iminosuccinate can either be hydrolysed to form oxaloacetate and NH3 or can be used by EC 2.5.1.72, quinolinate synthase, in the production of quinolinate. The enzyme is a member of the succinate dehydrogenase/fumarate-reductase family of enzymes .
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Pseudomonas aeruginosa
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Word Map
The taxonomic range for the selected organisms is: Pseudomonas aeruginosa
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
Reaction Schemes
Synonyms
l-aspartate oxidase, laspo, tl-laspo, stlaspo, l-asp oxidase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
LASPO
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oxidase, L-aspartate
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
oxidation
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oxidative deamination
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redox reaction
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reduction
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SYSTEMATIC NAME
IUBMB Comments
L-aspartate:oxygen oxidoreductase
A flavoprotein (FAD). L-Aspartate oxidase catalyses the first step in the de novo biosynthesis of NAD+ in some bacteria. O2 can be replaced by fumarate as electron acceptor, yielding succinate [5]. The ability of the enzyme to use both O2 and fumarate in cofactor reoxidation enables it to function under both aerobic and anaerobic conditions [5]. Iminosuccinate can either be hydrolysed to form oxaloacetate and NH3 or can be used by EC 2.5.1.72, quinolinate synthase, in the production of quinolinate. The enzyme is a member of the succinate dehydrogenase/fumarate-reductase family of enzymes [5].
CAS REGISTRY NUMBER
COMMENTARY hide
69106-47-4
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UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
A0A8I0ZJ91_PSEAI
538
0
59947
TrEMBL
-
A0A8G6CD92_PSEAI
538
0
60014
TrEMBL
-
A0A8G5MYQ1_PSEAI
538
0
60033
TrEMBL
-
A0A0C6F056_PSEAI
538
0
60019
TrEMBL
-
A0A7M3ERK9_PSEAI
538
0
60019
TrEMBL
-
A0A8G2R746_PSEAI
538
0
60005
TrEMBL
-
A0A6A9K082_PSEAI
538
0
60023
TrEMBL
-
A0A8G7H7H6_PSEAI
538
0
60005
TrEMBL
-
A0A2R3J4Q3_PSEAI
538
0
59982
TrEMBL
-
A0A7M3ATW3_PSEAI
538
0
60022
TrEMBL
-
A0A8B5A1Q1_PSEAI
538
0
60033
TrEMBL
-
A0A8G2RT78_PSEAI
538
0
59979
TrEMBL
-
A0A8G6CMT6_PSEAI
538
0
60067
TrEMBL
-
A0A8G1Q3C0_PSEAI
538
0
59906
TrEMBL
-
A0A5K1SHJ4_PSEAI
538
0
60079
TrEMBL
-
A0A0A8RMV5_PSEAI
538
0
59946
TrEMBL
-
A0A4P0TG24_PSEAI
488
0
54756
TrEMBL
-
A0A485GLJ9_PSEAI
277
0
31494
TrEMBL
-
A0A8G2Q2R0_PSEAI
538
0
60072
TrEMBL
-
A0A8G6ZBY2_PSEAI
538
0
60049
TrEMBL
-
A0A8G3ZFF2_PSEAI
538
0
60033
TrEMBL
-
A0A3S0IZF3_PSEAI
538
0
59955
TrEMBL
-
A0A0F6UGH5_PSEAI
538
0
60005
TrEMBL
-