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Information on EC 1.2.4.2 - oxoglutarate dehydrogenase (succinyl-transferring) and Organism(s) Caenorhabditis elegans

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EC Tree
IUBMB Comments
Contains thiamine diphosphate. It is a component of the multienzyme 2-oxoglutarate dehydrogenase complex, EC 1.2.1.105, in which multiple copies of it are bound to a core of molecules of EC 2.3.1.61, dihydrolipoyllysine-residue succinyltransferase, which also binds multiple copies of EC 1.8.1.4, dihydrolipoyl dehydrogenase. It does not act on free lipoamide or lipoyllysine, but only on the lipoyllysine residue in EC 2.3.1.61.
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This record set is specific for:
Caenorhabditis elegans
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Word Map
The taxonomic range for the selected organisms is: Caenorhabditis elegans
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
Synonyms
alpha-ketoglutarate dehydrogenase, 2-oxoglutarate dehydrogenase, kgdhc, alpha-ketoglutarate dehydrogenase complex, 2-oxoglutarate dehydrogenase complex, oxoglutarate dehydrogenase, kgdh, dhtkd1, ogdhl, ogdhc, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
2-ketoglutarate dehydrogenase
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2-OGDH
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2-oxoglutarate dehydrogenase
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2-oxoglutarate:lipoate oxidoreductase
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AKGDH
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alpha-ketoglutarate dehydrogenase
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alpha-ketoglutaric acid dehydrogenase
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alpha-ketoglutaric dehydrogenase
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alpha-KGD
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alpha-oxoglutarate dehydrogenase
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dehydrogenase, oxoglutarate
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ketoglutaric dehydrogenase
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OGDC
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oxoglutarate decarboxylase
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oxoglutarate dehydrogenase
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
oxidation
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oxidative decarboxylation
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redox reaction
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reduction
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SYSTEMATIC NAME
IUBMB Comments
2-oxoglutarate:[dihydrolipoyllysine-residue succinyltransferase]-lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-succinylating)
Contains thiamine diphosphate. It is a component of the multienzyme 2-oxoglutarate dehydrogenase complex, EC 1.2.1.105, in which multiple copies of it are bound to a core of molecules of EC 2.3.1.61, dihydrolipoyllysine-residue succinyltransferase, which also binds multiple copies of EC 1.8.1.4, dihydrolipoyl dehydrogenase. It does not act on free lipoamide or lipoyllysine, but only on the lipoyllysine residue in EC 2.3.1.61.
CAS REGISTRY NUMBER
COMMENTARY hide
9031-02-1
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UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
ODO1_CAEEL
1029
0
115661
Swiss-Prot
Mitochondrion (Reliability: 1)
DHTK1_CAEEL
911
0
102731
Swiss-Prot
Mitochondrion (Reliability: 3)