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Information on EC 1.2.1.11 - aspartate-semialdehyde dehydrogenase and Organism(s) Pseudomonas aeruginosa

for references in articles please use BRENDA:EC1.2.1.11
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Pseudomonas aeruginosa
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The taxonomic range for the selected organisms is: Pseudomonas aeruginosa
The enzyme appears in selected viruses and cellular organisms
Synonyms
asadh, aspartate semialdehyde dehydrogenase, aspartate-beta-semialdehyde dehydrogenase, aspartate-semialdehyde dehydrogenase, aspartate beta-semialdehyde dehydrogenase, asa dh, aspartic semialdehyde dehydrogenase, l-aspartate-beta-semialdehyde dehydrogenase, asd enzyme, ecasadh, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
ASA dehydrogenase
-
-
-
-
ASA DH
-
-
-
-
ASADH
-
-
-
-
aspartate semialdehyde dehydrogenase
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-
-
-
aspartic beta-semialdehyde dehydrogenase
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-
-
-
aspartic semialdehyde dehydrogenase
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-
-
-
dehydrogenase, aspartate semialdehyde
-
-
-
-
L-aspartate-beta-semialdehyde:NADP oxidoreductase (phosphorylating)
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-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
oxidation
-
-
-
-
Phosphorylation
-
-
-
-
redox reaction
-
-
-
-
reduction
-
-
-
-
SYSTEMATIC NAME
IUBMB Comments
L-aspartate-4-semialdehyde:NADP+ oxidoreductase (phosphorylating)
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CAS REGISTRY NUMBER
COMMENTARY hide
9000-98-0
-
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
L-4-aspartyl phosphate + NADPH
L-aspartate 4-semialdehyde + phosphate + NADP+
show the reaction diagram
-
-
?
L-aspartate 4-semialdehyde + phosphate + NADP+
L-4-aspartyl phosphate + NADPH
show the reaction diagram
-
-
r
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
L-4-aspartyl phosphate + NADPH
L-aspartate 4-semialdehyde + phosphate + NADP+
show the reaction diagram
-
-
?
COFACTOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.12
L-aspartate 4-semialdehyde
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TURNOVER NUMBER [1/s]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
160
L-aspartate 4-semialdehyde
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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
additional information
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
A0A8G4KQ57_PSEAI
336
0
35275
TrEMBL
-
A0A367M9S0_PSEAI
336
0
35319
TrEMBL
-
A0A8G2NF08_PSEAI
336
0
35424
TrEMBL
-
A0A2R3J384_PSEAI
370
0
40553
TrEMBL
-
A0A8G4AV85_PSEAI
336
0
35402
TrEMBL
-
A0A5K1SBC7_PSEAI
336
0
35307
TrEMBL
-
A0A8G6RIM8_PSEAI
336
0
35365
TrEMBL
-
A0A071KXU0_PSEAI
336
0
35335
TrEMBL
-
A0A431XCH6_PSEAI
336
0
35416
TrEMBL
-
A0A7M3B5X4_PSEAI
370
0
40505
TrEMBL
-
A0A8G2VRY7_PSEAI
336
0
35270
TrEMBL
-
A0A8G7DK92_PSEAI
370
0
40435
TrEMBL
-
A0A8F9JKN8_PSEAI
336
0
35310
TrEMBL
-
A0A8G4KHV0_PSEAI
336
0
35333
TrEMBL
-
A0A643J0M9_PSEAI
370
0
40523
TrEMBL
-
A0A8G2WK34_PSEAI
370
0
40443
TrEMBL
-
A0A6B1Y2R1_PSEAI
336
0
35363
TrEMBL
-
A0A069QBZ2_PSEAI
336
0
35349
TrEMBL
-
A0A8H1ACQ0_PSEAI
336
0
35303
TrEMBL
-
A0A8B5BEV6_PSEAI
336
0
35363
TrEMBL
-
A0A8G6V7Q2_PSEAI
370
0
40521
TrEMBL
-
A0A0A8RGE8_PSEAI
370
0
40398
TrEMBL
-
A0A8G6Y8I2_PSEAI
370
0
40501
TrEMBL
-
A0A8G6VCX5_PSEAI
370
0
40507
TrEMBL
-
A0A8G2R4T3_PSEAI
336
0
35319
TrEMBL
-
A0A8G4ABG4_PSEAI
336
0
35349
TrEMBL
-
A0A8G3ZII6_PSEAI
370
0
40465
TrEMBL
-
A0A659BMN8_PSEAI
336
0
35349
TrEMBL
-
A0A8G3G2L9_PSEAI
370
0
40564
TrEMBL
-
A0A8G4LDS2_PSEAI
336
0
35395
TrEMBL
-
A0A0C6EQW5_PSEAI
370
0
40495
TrEMBL
-
A0A8G5UBV4_PSEAI
336
0
35368
TrEMBL
-
A0A8G4CYP2_PSEAI
336
0
35317
TrEMBL
-
A0A509JM09_PSEAI
336
0
35393
TrEMBL
-
A0A367MB72_PSEAI
370
0
40409
TrEMBL
-
A0A8G5N2B4_PSEAI
336
0
35296
TrEMBL
-
A0A8G5JQH8_PSEAI
336
0
35410
TrEMBL
-
A0A8G7BCS1_PSEAI
370
0
40481
TrEMBL
-
A0A8G7HPU1_PSEAI
336
0
35335
TrEMBL
-
A0A8G4AWQ0_PSEAI
370
0
40437
TrEMBL
-
A0A8G6B9D0_PSEAI
336
0
35407
TrEMBL
-
A0A8G2VRU5_PSEAI
370
0
40527
TrEMBL
-
O87013_PSEAI
391
0
42089
TrEMBL
-
A0A8G4TW39_PSEAI
336
0
35296
TrEMBL
-
PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
using column chromatography on Q Sepharose XL and phenyl-Sepharose
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expressed in Escherichia coli
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Moore, R.A.; Bocik, W.E.; Viola, R.E.
Expression and purification of aspartate beta-semialdehyde dehydrogenase from infectious microorganisms
Protein Expr. Purif.
25
189-194
2002
Haemophilus influenzae, Helicobacter pylori (O25801), Helicobacter pylori, Pseudomonas aeruginosa (Q51344), Pseudomonas aeruginosa, Vibrio cholerae (P23247), Vibrio cholerae
Manually annotated by BRENDA team