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Information on EC 1.14.19.20 - DELTA7-sterol 5(6)-desaturase

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IUBMB Comments
This enzyme, found in eukaryotic organisms, catalyses the introduction of a double bond between the C5 and C6 carbons of the B ring of Delta7-sterols, to yield the corresponding Delta5,7-sterols. The enzymes from yeast, plants and vertebrates act on avenasterol, episterol, and lathosterol, respectively. The enzyme is located at the endoplasmic reticulum and is membrane bound.
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Word Map
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
Synonyms
erg3p, c-5 sterol desaturase, 5-des, fvc5sd, erg 3, lathosterol 5-desaturase, sterol c5-desaturase, sterol-c5-desaturase, des5a, delta7-sterol-c5(6)-desaturase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
a DELTA7-sterol + 2 ferrocytochrome b5 + O2 + 2 H+ = a DELTA5,7-sterol + 2 ferricytochrome b5 + 2 H2O
show the reaction diagram
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