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Aberrant Crypt Foci
Expression of vitamin D receptor and 25-hydroxyvitamin D3-1{alpha}-hydroxylase in normal and malignant human colon.
Abortion, Habitual
Women with Recurrent Miscarriage Have Decreased Expression of 25-Hydroxyvitamin D3-1?-Hydroxylase by the Fetal-Maternal Interface.
Abortion, Spontaneous
Altered decidual and placental catabolism of vitamin D may contribute to the aetiology of spontaneous miscarriage.
Abortion, Spontaneous
Women with Recurrent Miscarriage Have Decreased Expression of 25-Hydroxyvitamin D3-1?-Hydroxylase by the Fetal-Maternal Interface.
Acidosis
Acidosis inhibits 1,25-(OH)2D3 but not cAMP production in response to parathyroid hormone in the rat.
Acquired Immunodeficiency Syndrome
Vitamin-D pathway genes and HIV-1 disease progression in injection drug users.
Acute Coronary Syndrome
Contribution of CYP27B1 and CYP24A1 Genetic Variations to the Incidence of Acute Coronary Syndrome and to Vitamin D Serum Level.
Addison Disease
A haplotype of the CYP27B1 promoter is associated with autoimmune Addison's disease but not with Graves' disease in a UK population.
Addison Disease
A promoter polymorphism of the CYP27B1 gene is associated with Addison's disease, Hashimoto's thyroiditis, Graves' disease and type 1 diabetes mellitus in Germans.
Addison Disease
Association of Autoimmune Addison's Disease with Alleles of STAT4 and GATA3 in European Cohorts.
Addison Disease
Association of the CYP27B1 C(-1260)A Polymorphism with Autoimmune Addison's Disease.
Adenocarcinoma
Polymorphisms of Genes Related to Function and Metabolism of Vitamin D in Esophageal Adenocarcinoma.
Adenocarcinoma
Reduced 1alpha-hydroxylase activity in human prostate cancer cells correlates with decreased susceptibility to 25-hydroxyvitamin D3-induced growth inhibition.
Adenocarcinoma
Strategies and limitations associated with in vitro characterization of vitamin D receptor activators.
Adenocarcinoma
Vitamin D metabolic pathway genes and pancreatic cancer risk.
Adenoma
Altered expression of key players in vitamin D metabolism and signaling in malignant and benign thyroid tumors.
Adenoma
CYP24A1 and CYP27B1 Polymorphisms, Concentrations of Vitamin D Metabolites, and Odds of Colorectal Adenoma Recurrence.
Adenoma
Vitamin D Receptor Genotype, Vitamin D3 Supplementation, and Risk of Colorectal Adenomas: A Randomized Clinical Trial.
Alopecia
Disruption of the hedgehog signaling pathway contributes to the hair follicle cycling deficiency in Vdr knockout mice.
Alopecia
Study of gene expression alteration in male androgenetic alopecia: evidence of predominant molecular signaling pathways.
Amyotrophic Lateral Sclerosis
The vitamin D activator CYP27B1 is upregulated in muscle fibers in denervating disease and can track progression in amyotrophic lateral sclerosis.
Anemia
VDR gene polymorphisms impact on anemia at 2 weeks of anti-HCV therapy: a possible mechanism for early RBV-induced anemia.
Anemia
[Rickets/osteomalacia revisited. Drug-induced osteomalacia.]
Ascorbic Acid Deficiency
Ascorbic acid effects on vitamin D hormone metabolism and binding in guinea pigs.
Asthma
Allergen specific immunotherapy enhanced defense against bacteria via TGF-?1-induced CYP27B1 in asthma.
Asthma
Association of T-regulatory cells and CD23/CD21 expression with vitamin D in children with asthma.
Asthma
Associations of Genetic Polymorphisms Relevant to Metabolic Pathway of Vitamin D3 with Development and Prognosis of Childhood Bronchial Asthma.
Autoimmune Diseases
A promoter polymorphism of the CYP27B1 gene is associated with Addison's disease, Hashimoto's thyroiditis, Graves' disease and type 1 diabetes mellitus in Germans.
Autoimmune Diseases
Association between polymorphism of the vitamin D metabolism gene CYP27B1 and HLA-B27-associated uveitis. Is a state of relative immunodeficiency pathogenic in HLA B27-positive uveitis?
Autoimmune Diseases
Association study between vitiligo and autoimmune-related genes CYP27B1, REL, TNFAIP3, IL2 and IL21.
Autoimmune Diseases
Does vitamin D play a role in autoimmune endocrine disorders? A proof of concept.
Autoimmune Diseases
Polymorphisms in genetics of vitamin D metabolism confer susceptibility to ocular Behçet disease in a Chinese Han population.
Autoimmune Diseases
The CYP27B1 variant associated with an increased risk of autoimmune disease is underexpressed in tolerizing dendritic cells.
Bacterial Infections
Vitamin D receptor, vitamin D binding protein and CYP27B1 single nucleotide polymorphisms and susceptibility to viral infections in infants.
Barrett Esophagus
Polymorphisms of Genes Related to Function and Metabolism of Vitamin D in Esophageal Adenocarcinoma.
Bone Resorption
1,25-Dihydroxyvitamin D insufficiency accelerates age-related bone loss by increasing oxidative stress and cell senescence.
Bone Resorption
2,3,7,8-Tetrachlorodibenzo-p-dioxin dose-dependently increases bone mass and decreases marrow adiposity in juvenile mice.
Bone Resorption
Analysis of vitamin D metabolism gene expression in human bone: Evidence for autocrine control of bone remodelling.
Bone Resorption
Comparison of the biochemical responses to human parathyroid hormone-(1-31)NH2 and hPTH-(1-34) in healthy humans.
Bone Resorption
Effect of dietary phosphorus on circulating concentrations of 1,25-dihydroxyvitamin D and immunoreactive parathyroid hormone in children with moderate renal insufficiency.
Breast Neoplasms
25(OH)D3 and 1,25(OH)2D3 serum concentration and breast tissue expression of 1alpha-hydroxylase, 24-hydroxylase and Vitamin D receptor in women with and without breast cancer.
Breast Neoplasms
25-Hydroxyvitamin D(3) is an agonistic vitamin D receptor ligand.
Breast Neoplasms
25-Hydroxyvitamin D3 1alpha-hydroxylase expression in breast cancer and use of non-1alpha-hydroxylated vitamin D analogue.
Breast Neoplasms
25-Hydroxyvitamin D3 1alpha-hydroxylase splice variants in breast cell lines MCF-7 and MCF-10.
Breast Neoplasms
Alterations in Vitamin D signalling and metabolic pathways in breast cancer progression: a study of VDR, CYP27B1 and CYP24A1 expression in benign and malignant breast lesions Vitamin D pathways unbalanced in breast lesions.
Breast Neoplasms
Analysis of 25-hydroxyvitamin D3-1alpha-hydroxylase in normal and malignant breast tissue.
Breast Neoplasms
Analysis of the vitamin D system in cervical carcinomas, breast cancer and ovarian cancer.
Breast Neoplasms
Autocrine metabolism of vitamin D in normal and malignant breast tissue.
Breast Neoplasms
Biological actions of extra-renal 25-hydroxyvitamin D-1alpha-hydroxylase and implications for chemoprevention and treatment.
Breast Neoplasms
Equivalent anticancer activities of dietary vitamin D and calcitriol in an animal model of breast cancer: Importance of mammary CYP27B1 for treatment and prevention.
Breast Neoplasms
Expression of 25-hydroxyvitamin D-1-alpha-hydroxylase, and vitamin D receptor mRNA in normal and malignant breast tissue.
Breast Neoplasms
Expression of splice variants of 1alpha-hydroxylase in mcf-7 breast cancer cells.
Breast Neoplasms
Gene expression profiles of CYP24A1 and CYP27B1 in malignant and normal breast tissues.
Breast Neoplasms
Human mammary epithelial cells express CYP27B1 and are growth inhibited by 25-hydroxyvitamin D-3, the major circulating form of vitamin D-3.
Breast Neoplasms
MicroRNA-195 inhibits proliferation, invasion and metastasis in breast cancer cells by targeting FASN, HMGCR, ACACA and CYP27B1.
Breast Neoplasms
Multiple exposure to environmental factors and variations in CYP27B1 and the microRNA-binding site of IL-13 are associated with breast cancer risk.
Breast Neoplasms
Pharmacogenetics and aromatase inhibitor induced side effects in breast cancer patients.
Breast Neoplasms
Selective use of multiple vitamin D response elements underlies the 1 alpha,25-dihydroxyvitamin D3-mediated negative regulation of the human CYP27B1 gene.
Breast Neoplasms
Tumoral Vitamin D Synthesis by CYP27B1 1-?-Hydroxylase Delays Mammary Tumor Progression in the PyMT-MMTV Mouse Model and Its Action Involves NF-?B Modulation.
Breast Neoplasms
Vitamin D receptor (VDR) and metabolizing enzymes CYP27B1 and CYP24A1 in breast cancer.
Breast Neoplasms
Vitamin D status and breast cancer risk.
Breast Neoplasms
Vitamin D-1alpha-hydroxylase and vitamin D-24-hydroxylase in benign and malign breast tissue.
calcidiol 1-monooxygenase deficiency
1, 25-dihydroxy-vitamin D3 with tumor necrosis factor-alpha protects against rheumatoid arthritis by promoting p53 acetylation-mediated apoptosis via Sirt1 in synoviocytes.
calcidiol 1-monooxygenase deficiency
Genetic disorders and defects in vitamin d action.
calcidiol 1-monooxygenase deficiency
Genetics of vitamin D 1alpha-hydroxylase deficiency in 17 families.
calcidiol 1-monooxygenase deficiency
Human 25-hydroxyvitamin D-1alpha-hydroxylase: cloning, mutations, and gene expression.
calcidiol 1-monooxygenase deficiency
Novel gene mutations in patients with 1alpha-hydroxylase deficiency that confer partial enzyme activity in vitro.
calcidiol 1-monooxygenase deficiency
Vitamin D 1alpha-hydroxylase gene mutations in patients with 1alpha-hydroxylase deficiency.
calcidiol 1-monooxygenase deficiency
[Type 1 hypocalcemic pseudo-deficiency rickets caused by renal 25-hydroxycholecalciferol 1-hydroxylase deficiency (apropos of 1 case)]
Carcinogenesis
Analysis of 25-hydroxyvitamin D3-1alpha-hydroxylase in cervical tissue.
Carcinogenesis
CYP24A1 and CYP27B1 Polymorphisms Modulate Vitamin D Metabolism in Colon Cancer Cells.
Carcinogenesis
Dietary factors and polymorphisms in vitamin D metabolism genes: the risk and prognosis of colorectal cancer in northeast China.
Carcinogenesis
The 1,25-dihydroxyvitamin D(3)-independent actions of the vitamin D receptor in skin.
Carcinogenesis
Tumoral Vitamin D Synthesis by CYP27B1 1-?-Hydroxylase Delays Mammary Tumor Progression in the PyMT-MMTV Mouse Model and Its Action Involves NF-?B Modulation.
Carcinoma
25-hydroxy-vitamin d metabolism in human colon cancer cells during tumor progression.
Carcinoma
Alterations in Vitamin D signalling and metabolic pathways in breast cancer progression: a study of VDR, CYP27B1 and CYP24A1 expression in benign and malignant breast lesions Vitamin D pathways unbalanced in breast lesions.
Carcinoma
Analysis of the vitamin D system in cervical carcinomas, breast cancer and ovarian cancer.
Carcinoma
Analysis of the vitamin D system in cutaneous malignancies.
Carcinoma
Clonal differences in expression of 25-hydroxyvitamin D(3)-1alpha-hydroxylase, of 25-hydroxyvitamin D(3)-24-hydroxylase, and of the vitamin D receptor in human colon carcinoma cells: effects of epidermal growth factor and 1alpha,25-dihydroxyvitamin D(3).
Carcinoma
Decreased expression of CYP27B1 correlates with the increased aggressiveness of ovarian carcinomas.
Carcinoma
Expression and activity of vitamin D-metabolizing cytochrome P450s (CYP1alpha and CYP24) in human nonsmall cell lung carcinomas.
Carcinoma
Expression of 25-hydroxyvitamin D-1-alpha-hydroxylase mRNA in individuals with colorectal cancer.
Carcinoma
Metastatic growth of lung cancer cells is extremely reduced in Vitamin D receptor knockout mice.
Carcinoma
NNK-mediated upregulation of DEPDC1 stimulates the progression of oral squamous cell carcinoma by inhibiting CYP27B1 expression.
Carcinoma
Vitamin D hydroxylases CYP2R1, CYP27B1 and CYP24A1 in renal cell carcinoma.
Carcinoma
Vitamin D receptor, CYP27B1 and CYP24A1 genes polymorphisms association with oral cancer risk and survival.
Carcinoma 256, Walker
Evidence of 1,25-dihydroxyvitamin D synthesis by the rat Walker carcinosarcoma 256.
Carcinoma, Basal Cell
Analysis of the vitamin D system in cutaneous malignancies.
Carcinoma, Ductal
Vitamin D and the mammary gland: a review on its role in normal development and breast cancer.
Carcinoma, Hepatocellular
Marked increase of CYP24A1 mRNA level in hepatocellular carcinoma cell lines following vitamin D administration.
Carcinoma, Hepatocellular
[Vitamin D metabolism and signaling in human hepatocellular carcinoma and surrounding non-tumorous liver].
Carcinoma, Lewis Lung
Metastatic growth of lung cancer cells is extremely reduced in Vitamin D receptor knockout mice.
Carcinoma, Renal Cell
Vitamin D hydroxylases CYP2R1, CYP27B1 and CYP24A1 in renal cell carcinoma.
Carcinoma, Squamous Cell
Analysis of the vitamin D system in cutaneous malignancies.
Carcinoma, Squamous Cell
Targeted disruption of the 25-hydroxyvitamin D3 1alpha-hydroxylase gene in ras-transformed keratinocytes demonstrates that locally produced 1alpha,25-dihydroxyvitamin D3 suppresses growth and induces differentiation in an autocrine fashion.
Carcinosarcoma
Evidence of 1,25-dihydroxyvitamin D synthesis by the rat Walker carcinosarcoma 256.
Cardiomegaly
Targeted ablation of the vitamin D 1alpha-hydroxylase gene: getting to the heart of the matter.
Cardiomegaly
Vitamin D and Vitamin D Receptor Activators in Treatment of Hypertension and Cardiovascular Disease.
Chlamydia Infections
Specific polymorphisms in the vitamin D metabolism pathway are not associated with susceptibility to Chlamydia trachomatis infection in humans.
Choriocarcinoma
Metabolism of vitamin D in the human choriocarcinoma cell line JEG-3.
Colitis
Altered endocrine and autocrine metabolism of vitamin D in a mouse model of gastrointestinal inflammation.
Colitis
Microbiota-dependent induction of colonic Cyp27b1 is associated with colonic inflammation: Implication of locally produced 1,25-dihydroxyvitamin D in inflammatory regulation in the colon.
Colitis
Murine CD8+ T cells but not macrophages express the vitamin D 1?-hydroxylase.
Colitis, Ulcerative
Interleukin-13 Inhibits Expression of cyp27b1 in Peripheral CD14+ Cells That Is Correlated With Vertebral Bone Mineral Density of Patients With Ulcerative Colitis.
Colitis, Ulcerative
Microbiota-dependent induction of colonic Cyp27b1 is associated with colonic inflammation: Implication of locally produced 1,25-dihydroxyvitamin D in inflammatory regulation in the colon.
Colonic Neoplasms
Analysis of 25-hydroxyvitamin D3-1alpha-hydroxylase in cervical tissue.
Colonic Neoplasms
Analysis of 25-hydroxyvitamin D3-1alpha-hydroxylase in normal and malignant breast tissue.
Colonic Neoplasms
Biological actions of extra-renal 25-hydroxyvitamin D-1alpha-hydroxylase and implications for chemoprevention and treatment.
Colonic Neoplasms
CYP24A1 and CYP27B1 Polymorphisms Modulate Vitamin D Metabolism in Colon Cancer Cells.
Colonic Neoplasms
Expression of 25-hydroxyvitamin D-1alpha-hydroxylase (1alphaOHase, CYP27B1) splice variants in HaCaT keratinocytes and other skin cells: modulation by culture conditions and UV-B treatment in vitro.
Colonic Neoplasms
Genetic variation in calcium-sensing receptor and risk for colon cancer.
Colonic Neoplasms
Immunoglobulin E induces colon cancer cell apoptosis via enhancing cyp27b1 expression.
Colonic Neoplasms
Vitamin D related genes, CYP24A1 and CYP27B1, and colon cancer risk.
Colorectal Neoplasms
A randomized clinical trial of the effects of supplemental calcium and vitamin D3 on markers of their metabolism in normal mucosa of colorectal adenoma patients.
Colorectal Neoplasms
Colonic epithelial cell proliferation decreases with increasing levels of serum 25-hydroxy vitamin D.
Colorectal Neoplasms
CYP24A1 and CYP27B1 Polymorphisms Modulate Vitamin D Metabolism in Colon Cancer Cells.
Colorectal Neoplasms
CYP27B1 Gene Polymorphism rs10877012 in Patients Diagnosed with Colorectal Cancer.
Colorectal Neoplasms
Dysregulation of vitamin D synthesis pathway genes in colorectal cancer: A case-control study.
Colorectal Neoplasms
Expression of 25-hydroxyvitamin D-1-alpha-hydroxylase mRNA in individuals with colorectal cancer.
Colorectal Neoplasms
Expression of vitamin D receptor and 25-hydroxyvitamin D3-1{alpha}-hydroxylase in normal and malignant human colon.
Colorectal Neoplasms
Genetic polymorphisms of vitamin D metabolism genes and serum level of vitamin D in colorectal cancer.
Colorectal Neoplasms
Genetic polymorphisms of vitamin D receptor (VDR), CYP27B1 and CYP24A1 genes and the risk of colorectal cancer.
Colorectal Neoplasms
Phytoestrogens and vitamin D metabolism: a new concept for the prevention and therapy of colorectal, prostate, and mammary carcinomas.
Colorectal Neoplasms
Relative Expression of Vitamin D Hydroxylases, CYP27B1 and CYP24A1, and of Cyclooxygenase-2 and Heterogeneity of Human Colorectal Cancer in Relation to Age, Gender, Tumor Location, and Malignancy: Results from Factor and Cluster Analysis.
Colorectal Neoplasms
The Vitamin D endocrine system of the gut--its possible role in colorectal cancer prevention.
COVID-19
Evaluation of expression of VDR-associated lncRNAs in COVID-19 patients.
Cysts
Altered vitamin D metabolic system in follicular cysts of sows.
Diabetes Mellitus
A promoter polymorphism of the CYP27B1 gene is associated with Addison's disease, Hashimoto's thyroiditis, Graves' disease and type 1 diabetes mellitus in Germans.
Diabetes Mellitus
Association study of the vitamin D: 1alpha-hydroxylase (CYP1alpha) gene and type 2 diabetes mellitus in a Polish population.
Diabetes Mellitus
CYP27B1 polymorphisms variants are associated with type 1 diabetes mellitus in Germans.
Diabetes Mellitus
The Association between Polymorphisms of Vitamin D Metabolic-Related Genes and Vitamin D3 Supplementation in Type 2 Diabetic Patients.
Diabetes Mellitus
Vitamin D 1alpha-hydroxylase (CYP1alpha) polymorphism in Graves' disease, Hashimoto's thyroiditis and type 1 diabetes mellitus.
Diabetes Mellitus, Type 1
A promoter polymorphism of the CYP27B1 gene is associated with Addison's disease, Hashimoto's thyroiditis, Graves' disease and type 1 diabetes mellitus in Germans.
Diabetes Mellitus, Type 1
A rare haplotype of the vitamin D receptor gene is protective against diabetic nephropathy.
Diabetes Mellitus, Type 1
Association of the vitamin D metabolism gene CYP27B1 with type 1 diabetes.
Diabetes Mellitus, Type 1
CYP27B1 polymorphisms variants are associated with type 1 diabetes mellitus in Germans.
Diabetes Mellitus, Type 1
CYP2R1 (vitamin D 25-hydroxylase) gene is associated with susceptibility to type 1 diabetes and vitamin D levels in Germans.
Diabetes Mellitus, Type 1
CYP2R1-, CYP27B1- and CYP24-mRNA expression in German type 1 diabetes patients.
Diabetes Mellitus, Type 1
Inherited Variation in Vitamin D Genes Is Associated With Predisposition to Autoimmune Disease Type 1 Diabetes.
Diabetes Mellitus, Type 1
PTPN22, PDCD1 and CYP27B1 polymorphisms and susceptibility to type 1 diabetes in Polish patients.
Diabetes Mellitus, Type 1
Synergism of CYP2R1 and CYP27B1 polymorphisms and susceptibility to type 1 diabetes in Egyptian children.
Diabetes Mellitus, Type 1
Vitamin D 1alpha-hydroxylase (CYP1alpha) polymorphism in Graves' disease, Hashimoto's thyroiditis and type 1 diabetes mellitus.
Diabetes Mellitus, Type 2
Association study of the vitamin D: 1alpha-hydroxylase (CYP1alpha) gene and type 2 diabetes mellitus in a Polish population.
Diabetes, Gestational
Gestational diabetes mellitus and vitamin D deficiency: genetic contribution of CYP27B1 and CYP2R1 polymorphisms.
Diabetes, Gestational
Placenta expression of vitamin D and related genes in pregnant women with gestational diabetes mellitus.
Diabetes, Gestational
Vitamin D deficiency in gestational diabetes mellitus and the role of the placenta.
Dysgerminoma
Increased expression of 25-hydroxyvitamin D-1alpha-hydroxylase in dysgerminomas: a novel form of humoral hypercalcemia of malignancy.
Dysgerminoma
Prolonged hypercalcemia following resection of dysgerminoma: a case report.
Encephalomyelitis
Vitamin D3-mediated resistance to a multiple sclerosis model disease depends on myeloid cell 1,25-dihydroxyvitamin D3 synthesis and correlates with increased CD4+ T cell CTLA-4 expression.
Encephalomyelitis, Autoimmune, Experimental
Vitamin D3-mediated resistance to a multiple sclerosis model disease depends on myeloid cell 1,25-dihydroxyvitamin D3 synthesis and correlates with increased CD4+ T cell CTLA-4 expression.
Endocrine System Diseases
Association of Vitamin D Pathway Gene CYP27B1 and CYP2R1 Polymorphisms with Autoimmune Endocrine Disorders: A Meta-Analysis.
Endometrial Neoplasms
Expression of 25 hydroxyvitamin D3-1alpha-hydroxylase in human endometrial tissue.
Endometriosis
Cycling and early pregnant endometrium as a site of regulated expression of the vitamin D system.
Familial Hypophosphatemic Rickets
Abnormal regulation of renal 25-hydroxyvitamin D-1alpha-hydroxylase activity in X-linked hypophosphatemia: a translational or post-translational defect.
Familial Hypophosphatemic Rickets
Calcitonin stimulation of renal 25-hydroxyvitamin D-1 alpha-hydroxylase activity in hypophosphatemic mice. Evidence that the regulation of calcitriol production is not universally abnormal in X-linked hypophosphatemia.
Familial Hypophosphatemic Rickets
Normal calcitonin stimulation of serum calcitriol in patients with X-linked hypophosphatemic rickets.
Fatty Liver
Genetic Polymorphism of Vitamin D Family Genes CYP2R1, CYP24A1, and CYP27B1 Are Associated With a High Risk of Non-alcoholic Fatty Liver Disease: A Case-Control Study.
Fibrosarcoma
Increase in serum 1,25-dihydroxyvitamin D and hypercalcaemia in a patient with inflammatory myofibroblastic tumour.
Genetic Diseases, Inborn
[Long term follow up of a patient with type I vitamin D-dependent rickets].
Glioblastoma
Amplicons on chromosome 12q13-21 in glioblastoma recurrences.
Glioblastoma
Expression analysis of CYP27B1 in tumor biopsies and cell cultures.
Glioblastoma
Vitamin D(3) metabolism in human glioblastoma multiforme: functionality of CYP27B1 splice variants, metabolism of calcidiol, and effect of calcitriol.
Glioma
No evidence for amplification of 25-hydroxyvitamin D-1alpha-OHase (1alpha-OHase) or 1,25-dihydroxyvitamin D-24-OHase (24-OHase) genes in malignant melanoma (MM).
Gout
Decreased serum concentrations of 1,25(OH)2-vitamin D3 in patients with gout.
Granuloma
A Case of Hypercalcemia and Overexpression of CYP27B1 in Skeletal Muscle Lesions in a Patient with HIV Infection After Cosmetic Injections with Polymethylmethacrylate (PMMA) for Wasting.
Granuloma
Hypercalcemia after cosmetic oil injections: Unravelling etiology, pathogenesis and severity.
Granuloma
Hypercalcemia Associated with Mineral Oil-Induced Sclerosing Paraffinomas.
Granuloma
Synthol systemic complications: Hypercalcemia and pulmonary granulomatosis. A case report.
Graves Disease
A haplotype of the CYP27B1 promoter is associated with autoimmune Addison's disease but not with Graves' disease in a UK population.
Graves Disease
A promoter polymorphism of the CYP27B1 gene is associated with Addison's disease, Hashimoto's thyroiditis, Graves' disease and type 1 diabetes mellitus in Germans.
Graves Disease
CYP27B1 gene polymorphism is associated with Graves' disease in a Polish population study.
Graves Disease
Vitamin D 1alpha-hydroxylase (CYP1alpha) polymorphism in Graves' disease, Hashimoto's thyroiditis and type 1 diabetes mellitus.
Heart Failure
Genetic variation in CYP27B1 is associated with congestive heart failure in patients with hypertension.
Hepatitis C
Impact of CYP2R1, CYP27A1 and CYP27B1 genetic polymorphisms controlling vitamin D metabolism on susceptibility to hepatitis C virus infection in a high-risk Chinese population.
Hepatitis C, Chronic
Vitamin D pathway gene variants and HCV-2/3 therapy outcomes.
HIV Infections
A Case of Hypercalcemia and Overexpression of CYP27B1 in Skeletal Muscle Lesions in a Patient with HIV Infection After Cosmetic Injections with Polymethylmethacrylate (PMMA) for Wasting.
Hypercalcemia
1alpha-Hydroxylase transactivation by gamma-interferon in murine macrophages requires enhanced C/EBPbeta expression and activation.
Hypercalcemia
25-Hydroxyvitamin D3 1alpha-hydroxylase expression in breast cancer and use of non-1alpha-hydroxylated vitamin D analogue.
Hypercalcemia
A Case of Hypercalcemia and Overexpression of CYP27B1 in Skeletal Muscle Lesions in a Patient with HIV Infection After Cosmetic Injections with Polymethylmethacrylate (PMMA) for Wasting.
Hypercalcemia
A case with severe hypercalcemia in multiple organ dysfunction syndrome: Role of elevated circulating 1alpha,25(OH)(2)VitD levels.
Hypercalcemia
A novel vitamin D gene therapy for acute myeloid leukemia.
Hypercalcemia
Conflicting actions of parathyroid hormone-related protein and serum calcium as regulators of 25-hydroxyvitamin D(3)-1 alpha-hydroxylase expression in a nude rat model of humoral hypercalcemia of malignancy.
Hypercalcemia
Expression and activity of vitamin D-metabolizing cytochrome P450s (CYP1alpha and CYP24) in human nonsmall cell lung carcinomas.
Hypercalcemia
Function in athymic nude mice of parathyroid heterografts from patients with primary hyperparathyroidism and secondary hyperparathyroidism.
Hypercalcemia
Hepatocellular carcinoma cells express 25(OH)D-1?-hydroxylase and are able to convert 25(OH)D to 1?,25(OH)?D, leading to the 25(OH)D-induced growth inhibition.
Hypercalcemia
Hypercalcemia and Overexpression of CYP27B1 in a Patient with Nephrogenic Systemic Fibrosis: Clinical Vignette and Literature Review.
Hypercalcemia
Hypercalcemia Associated with Mineral Oil-Induced Sclerosing Paraffinomas.
Hypercalcemia
Hypercalcemia produced by parathyroid hormone suppresses experimental autoimmune encephalomyelitis in female but not male mice.
Hypercalcemia
Identification of 25-hydroxyvitamin D3 1alpha-hydroxylase gene expression in macrophages.
Hypercalcemia
In silico identification of novel transcription factors associated with CYP27B1 transcriptional regulation in LPS-challenged mononuclear phagocytes.
Hypercalcemia
Increased expression of 25-hydroxyvitamin D-1alpha-hydroxylase in dysgerminomas: a novel form of humoral hypercalcemia of malignancy.
Hypercalcemia
Rare Causes of Calcitriol-Mediated Hypercalcemia: A Case Report and Literature Review.
Hypercalcemia
Reduced 1alpha-hydroxylase activity in human prostate cancer cells correlates with decreased susceptibility to 25-hydroxyvitamin D3-induced growth inhibition.
Hypercalcemia
Synthol systemic complications: Hypercalcemia and pulmonary granulomatosis. A case report.
Hypercalcemia
The in vitro evaluation of 25-hydroxyvitamin D3 and 19-nor-1alpha,25-dihydroxyvitamin D2 as therapeutic agents for prostate cancer.
Hypercalcemia
The phosphatonins and the regulation of phosphate transport and vitamin D metabolism.
Hypercalcemia
Vitamin D-mediated hypercalcemia in slack skin disease: evidence for involvement of extrarenal 25-hydroxyvitamin D 1alpha-hydroxylase.
Hyperparathyroidism
Analysis of CYP27B1, encoding 25-hydroxyvitamin D-1alpha-hydroxylase, as a candidate tumor suppressor gene in primary and severe secondary/tertiary hyperparathyroidism.
Hyperparathyroidism
Calcitonin is a major regulator for the expression of renal 25-hydroxyvitamin D3-1alpha-hydroxylase gene in normocalcemic rats.
Hyperparathyroidism
Effect of dietary phosphorus on circulating concentrations of 1,25-dihydroxyvitamin D and immunoreactive parathyroid hormone in children with moderate renal insufficiency.
Hyperparathyroidism
Hypercalcemic hyperparathyroidism complicating oncogenic osteomalacia. Effect of successful tumor resection on mineral homeostasis.
Hyperparathyroidism
Hypervitaminosis D mediates compensatory Ca2+ hyperabsorption in TRPV5 knockout mice.
Hyperparathyroidism
Increased 25-hydroxyvitamin D3 1alpha-hydroxylase and reduced 25-hydroxyvitamin D3 24-hydroxylase expression in parathyroid tumors--new prospects for treatment of hyperparathyroidism with vitamin d.
Hyperparathyroidism
Regulation of the epithelial Ca2+ channels in small intestine as studied by quantitative mRNA detection.
Hyperparathyroidism
Skeletal toxicity resulting from exposure of growing male rats to coplanar PCB 126 is associated with disruption of calcium homeostasis and the GH-IGF-1 axis and direct effects on bone formation.
Hyperparathyroidism
Vitamin D insufficiency and hyperparathyroidism in children with chronic kidney disease.
Hyperparathyroidism, Primary
Function in athymic nude mice of parathyroid heterografts from patients with primary hyperparathyroidism and secondary hyperparathyroidism.
Hyperparathyroidism, Secondary
25-Hydroxyvitamin D3 1alpha-hydroxylase expression in breast cancer and use of non-1alpha-hydroxylated vitamin D analogue.
Hyperparathyroidism, Secondary
Absence of Calcitriol Causes Increased Lactational Bone Loss and Lower Milk Calcium but Does Not Impair Post-lactation Bone Recovery in Cyp27b1 Null Mice.
Hyperparathyroidism, Secondary
Cardiovascular disease in chronic kidney failure: the role of VDR activators.
Hyperparathyroidism, Secondary
Role of the vitamin D-endocrine system in the pathophysiology of postmenopausal osteoporosis.
Hyperparathyroidism, Secondary
Vitamin D and Vitamin D Receptor Activators in Treatment of Hypertension and Cardiovascular Disease.
Hyperphosphatemia
FGF receptors control vitamin D and phosphate homeostasis by mediating renal FGF23 signaling and regulating FGF23 expression in bone.
Hyperphosphatemia
The phosphatonins and the regulation of phosphate transport and vitamin D metabolism.
Hyperphosphatemia
Ubiquitin COOH-terminal hydrolase L1 deletion is associated with urinary ?-klotho deficiency and perturbed phosphate homeostasis.
Hypertension
Genetic variation in CYP27B1 is associated with congestive heart failure in patients with hypertension.
Hypertension
Targeted ablation of the vitamin D 1alpha-hydroxylase gene: getting to the heart of the matter.
Hypertension
Vitamin D and Vitamin D Receptor Activators in Treatment of Hypertension and Cardiovascular Disease.
Hyperthyroidism
Thyroid hormones decrease plasma 1?,25-dihydroxyvitamin D levels through transcriptional repression of the renal 25-hydroxyvitamin D3 1?-hydroxylase gene (CYP27B1).
Hypocalcemia
Absence of Calcitriol Causes Increased Lactational Bone Loss and Lower Milk Calcium but Does Not Impair Post-lactation Bone Recovery in Cyp27b1 Null Mice.
Hypocalcemia
Bone marrow ablation demonstrates that excess endogenous parathyroid hormone plays distinct roles in trabecular and cortical bone.
Hypocalcemia
High dietary vitamin D prevents hypocalcemia and osteomalacia in CYP27B1 knockout mice.
Hypocalcemia
Inactivating mutations in the 25-hydroxyvitamin D3 1alpha-hydroxylase gene in patients with pseudovitamin D-deficiency rickets.
Hypocalcemia
Metabolism of 25-hydroxyvitamin D3 in renal slices from the X-linked hypophosphatemic (Hyp) mouse: abnormal response to fall in serum calcium.
Hypocalcemia
Novel gene mutations in patients with 1alpha-hydroxylase deficiency that confer partial enzyme activity in vitro.
Hypocalcemia
Regulation of renal vitamin D receptor is an important determinant of 1alpha,25-dihydroxyvitamin D(3) levels in vivo.
Hypocalcemia
Regulation of the epithelial Ca2+ channels in small intestine as studied by quantitative mRNA detection.
Hypocalcemia
Survival of vitamin D-deficient embryos: time and choice of cholecalciferol or its metabolites for treatment in ovo.
Hypocalcemia
Thyroid hormones decrease plasma 1?,25-dihydroxyvitamin D levels through transcriptional repression of the renal 25-hydroxyvitamin D3 1?-hydroxylase gene (CYP27B1).
Hypocalcemia
Vitamin D 1alpha-hydroxylase gene mutations in patients with 1alpha-hydroxylase deficiency.
Hypoparathyroidism
Genetic models show that parathyroid hormone and 1,25-dihydroxyvitamin D3 play distinct and synergistic roles in postnatal mineral ion homeostasis and skeletal development.
Hypophosphatemia
1alpha-Hydroxylase gene ablation and Pi supplementation inhibit renal calcification in mice homozygous for the disrupted Npt2a gene.
Hypophosphatemia
Abnormal parathyroid hormone stimulation of 25-hydroxyvitamin D-1 alpha-hydroxylase activity in the hypophosphatemic mouse. Evidence for a generalized defect of vitamin D metabolism.
Hypophosphatemia
Absence of Calcitriol Causes Increased Lactational Bone Loss and Lower Milk Calcium but Does Not Impair Post-lactation Bone Recovery in Cyp27b1 Null Mice.
Hypophosphatemia
Calcitonin stimulation of renal 25-hydroxyvitamin D-1 alpha-hydroxylase activity in hypophosphatemic mice. Evidence that the regulation of calcitriol production is not universally abnormal in X-linked hypophosphatemia.
Hypophosphatemia
Dietary phosphorus deprivation induces 25-hydroxyvitamin D(3) 1alpha-hydroxylase gene expression.
Hypophosphatemia
Disordered regulation of renal 25-hydroxyvitamin D-1alpha-hydroxylase gene expression by phosphorus in X-linked hypophosphatemic (hyp) mice.
Hypophosphatemia
Klotho gene, phosphocalcic metabolism, and survival in dialysis.
Hypophosphatemia
Marked hypophosphatemia with decreased serum 1,25-dihydroxyvitamin D in a patient with hepatocellular carcinoma complicating liver cirrhosis.
Hypophosphatemia
Media calcium attenuates mitochondrial 1,25(OH)2D production in phosphorus or vitamin D-deprived rats.
Hypophosphatemia
Normal calcitonin stimulation of serum calcitriol in patients with X-linked hypophosphatemic rickets.
Hypophosphatemia
Renal calcitriol synthesis and serum phosphorus in response to dietary phosphorus restriction and anabolic agents.
Hypophosphatemia
Secreted frizzled-related protein-4 reduces sodium-phosphate co-transporter abundance and activity in proximal tubule cells.
Hypophosphatemia
The phosphatonins and the regulation of phosphate transport and vitamin D metabolism.
Hypophosphatemia
[Bone mineral metabolism: recent data and perspectives related to osteogenesis]
Hypophosphatemia
[The role of phosphatonin in phosphate metabolism]
Hypophosphatemia, Familial
A case of X-linked hypophosphatemic rickets: complications and the therapeutic use of cinacalcet.
Hypophosphatemia, Familial
Secreted frizzled-related protein-4 reduces sodium-phosphate co-transporter abundance and activity in proximal tubule cells.
Infections
Altered decidual and placental catabolism of vitamin D may contribute to the aetiology of spontaneous miscarriage.
Infections
Calcitriol increases nitric oxide production and modulates microbicidal capacity against Mycobacterium bovis in bovine macrophages.
Infections
Effect of 25-hydroxyvitamin D3 on rotavirus replication and gene expressions of RIG-I signalling molecule in porcine rotavirus-infected IPEC-J2 cells.
Infections
Human Metapneumovirus Infection Inhibits Cathelicidin Antimicrobial Peptide Expression in Human Macrophages.
Infections
Impact of CYP2R1, CYP27A1 and CYP27B1 genetic polymorphisms controlling vitamin D metabolism on susceptibility to hepatitis C virus infection in a high-risk Chinese population.
Infections
Intrinsic activation of the vitamin D antimicrobial pathway by M. leprae infection is inhibited by type I IFN.
Infections
Regulation of intracrine production of 1,25-dihydroxyvitamin D and its role in innate immune defense against infection.
Infections
Short communication: Vitamin D status and responses in dairy cows naturally infected with Mycobacterium avium ssp. paratuberculosis.
Infections
Vitamin D Is Required for ILC3 Derived IL-22 and Protection From Citrobacter rodentium Infection.
Infections
Vitamin D mediates the relationship between placental cathelicidin and group B streptococcus colonization during pregnancy.
Infections
Vitamin D, infections and immunity.
Infections
Vitamin D-related gene polymorphism predict treatment response to pegylated interferon-based therapy in Thai chronic hepatitis C patients.
Infections
Vitamin-D pathway genes and HIV-1 disease progression in injection drug users.
Insulin Resistance
Role of vitamin d in insulin resistance.
Kidney Diseases
Use of vitamin D in chronic kidney disease patients.
Kidney Failure, Chronic
A rare haplotype of the vitamin D receptor gene is protective against diabetic nephropathy.
Kidney Failure, Chronic
Gene expression of vitamin D hydroxylase and megalin in the remnant kidney of nephrectomized rats.
Kidney Failure, Chronic
Impaired Vitamin D Signaling Is Associated With Frequent Development of Renal Cell Tumor in End-stage Kidney Disease.
Kidney Failure, Chronic
Positive and negative regulations of the renal 25-hydroxyvitamin D3 1alpha-hydroxylase gene by parathyroid hormone, calcitonin, and 1alpha,25(OH)2D3 in intact animals.
Leiomyoma
Human uterine leiomyoma contains low levels of 1, 25 dihdroxyvitamin D3, and shows dysregulated expression of vitamin D metabolizing enzymes.
Leprosy
Intrinsic activation of the vitamin D antimicrobial pathway by M. leprae infection is inhibited by type I IFN.
Leprosy
Reanalysis and integration of public microarray datasets reveals novel host genes modulated in leprosy.
Lichen Planus, Oral
Association of vdr, cyp27b1, cyp24a1 and mthfr gene polymorphisms with oral lichen planus risk.
Lichen Planus, Oral
Single Nucleotide Polymorphisms in 25-Hydroxyvitamin D3 1-Alpha-Hydroxylase (CYP27B1) Gene: The Risk of Malignant Tumors and Other Chronic Diseases.
Liver Diseases
Genetic Polymorphism of Vitamin D Family Genes CYP2R1, CYP24A1, and CYP27B1 Are Associated With a High Risk of Non-alcoholic Fatty Liver Disease: A Case-Control Study.
Lung Neoplasms
Increased expression of the 25-hydroxyvitamin D(3)-1alpha-hydroxylase gene in alveolar macrophages of patients with lung cancer.
Lymphatic Metastasis
Vitamin D receptor and progesterone receptor protein and gene expression in papillary thyroid carcinomas: associations with histological features.
Lymphoma
Methotrexate-induced iatrogenic immunodeficiency-associated lymphoproliferative disorder causing hypercalcaemia.
Lymphoma
Vitamin D-mediated hypercalcemia in lymphoma: evidence for hormone production by tumor-adjacent macrophages.
Lymphoma, Non-Hodgkin
Single Nucleotide Polymorphisms in 25-Hydroxyvitamin D3 1-Alpha-Hydroxylase (CYP27B1) Gene: The Risk of Malignant Tumors and Other Chronic Diseases.
Lymphoma, T-Cell, Cutaneous
Vitamin D-mediated hypercalcemia in slack skin disease: evidence for involvement of extrarenal 25-hydroxyvitamin D 1alpha-hydroxylase.
Malnutrition
Reduced fetal vitamin D status by maternal undernutrition during discrete gestational windows in sheep.
Malnutrition
Role of the vitamin D-endocrine system in the pathophysiology of postmenopausal osteoporosis.
Melanoma
Antiproliferative Activity of Non-Calcemic Vitamin D Analogs on Human Melanoma Lines in Relation to VDR and PDIA3 Receptors.
Melanoma
CYP24A1 expression inversely correlates with melanoma progression: clinic-pathological studies.
Melanoma
Differential biological effects of 1,25-dihydroxyVitamin D3 on melanoma cell lines in vitro.
Melanoma
Expression of the vitamin D-activating enzyme 1?-hydroxylase (CYP27B1) decreases during melanoma progression.
Melanoma
No association of vitamin D metabolism-related polymorphisms and melanoma risk as well as melanoma prognosis: a case-control study.
Melanoma
On the relationship between VDR, ROR? and ROR? receptors expression and HIF1-? levels in human melanomas.
Melanoma
On the role of classical and novel forms of vitamin D in melanoma progression and management.
Melanoma
Vitamin D receptors (VDR), hydroxylases CYP27B1 and CYP24A1 and retinoid-related orphan receptors (ROR) level in human uveal tract and ocular melanoma with different melanization levels.
Melanoma
Vitamin D signaling and melanoma: role of vitamin D and its receptors in melanoma progression and management.
Mouth Neoplasms
Vitamin D receptor, CYP27B1 and CYP24A1 genes polymorphisms association with oral cancer risk and survival.
Multiple Sclerosis
Analysis of CYP27B1 in multiple sclerosis.
Multiple Sclerosis
Association between age at onset of multiple sclerosis and vitamin D level-related factors.
Multiple Sclerosis
Confirmation of association between multiple sclerosis and CYP27B1.
Multiple Sclerosis
No evidence for a role of rare CYP27B1 functional variations in multiple sclerosis.
Multiple Sclerosis
No evidence for a role of rare CYP27B1 variants in Austrian multiple sclerosis patients.
Multiple Sclerosis
No evidence of association between mutant alleles of the CYP27B1 gene and multiple sclerosis.
Multiple Sclerosis
Rare variants in the CYP27B1 gene are associated with multiple sclerosis.
Multiple Sclerosis
Single Nucleotide Polymorphisms in 25-Hydroxyvitamin D3 1-Alpha-Hydroxylase (CYP27B1) Gene: The Risk of Malignant Tumors and Other Chronic Diseases.
Multiple Sclerosis
The Association Between Genetic Polymorphism rs703842 in CYP27B1 and Multiple Sclerosis: A Meta-Analysis.
Multiple Sclerosis
The association of rs703842 variants in CYP27B1 with multiple sclerosis susceptibility is influenced by the HLA-DRB1*15:01 allele in Slovaks.
Multiple Sclerosis
Variants of CYP27B1 are associated with both multiple sclerosis and neuromyelitis optica patients in Han Chinese population.
Multiple Sclerosis
VDBP, CYP27B1, and 25-Hydroxyvitamin D Gene Polymorphism Analyses in a Group of Sicilian Multiple Sclerosis Patients.
Multiple Sclerosis
Vitamin D Regulates MerTK-Dependent Phagocytosis in Human Myeloid Cells.
Multiple Sclerosis
[Association between vitamin D status and CYP27b1 and CYP24A1 gene polymorphisms in patients with multiple sclerosis in the Altai region].
Multiple Sclerosis
[Association of vitamin D metabolism enzyme gene polymorphisms with multiple sclerosis risk: pilot study].
Multiple Sclerosis, Relapsing-Remitting
Down-regulation of CYP27B1 gene expression in Iranian patients with relapsing-remitting multiple sclerosis.
Muscle Cramp
Increased brain vitamin D receptor expression and decreased expression of cathelicidin antimicrobial peptide in individuals who died by suicide.
Muscular Atrophy
Modified expression of vitamin D receptor and CYP27B1 in denervation-induced muscle atrophy.
Muscular Diseases
The vitamin D activator CYP27B1 is upregulated in muscle fibers in denervating disease and can track progression in amyotrophic lateral sclerosis.
Neoplasm Metastasis
CYP27A1 and CYP24 expression as a function of malignant transformation in the colon.
Neoplasm Metastasis
Decreased expression of CYP27B1 correlates with the increased aggressiveness of ovarian carcinomas.
Neoplasm Metastasis
Expression of the vitamin D-activating enzyme 1?-hydroxylase (CYP27B1) decreases during melanoma progression.
Neoplasm Metastasis
Expression of vitamin D receptor and 25-hydroxyvitamin D3-1{alpha}-hydroxylase in normal and malignant human colon.
Neoplasm Metastasis
MicroRNA-195 inhibits proliferation, invasion and metastasis in breast cancer cells by targeting FASN, HMGCR, ACACA and CYP27B1.
Neoplasm Metastasis
No evidence for amplification of 25-hydroxyvitamin D-1alpha-OHase (1alpha-OHase) or 1,25-dihydroxyvitamin D-24-OHase (24-OHase) genes in malignant melanoma (MM).
Neoplasm Metastasis
On the relationship between VDR, ROR? and ROR? receptors expression and HIF1-? levels in human melanomas.
Neoplasm Metastasis
Vitamin D receptor and progesterone receptor protein and gene expression in papillary thyroid carcinomas: associations with histological features.
Neoplasms
25(OH)D Is Effective to Repress Human Cholangiocarcinoma Cell Growth through the Conversion of 25(OH)D to 1?,25(OH)?D?.
Neoplasms
25(OH)D3 and 1,25(OH)2D3 serum concentration and breast tissue expression of 1alpha-hydroxylase, 24-hydroxylase and Vitamin D receptor in women with and without breast cancer.
Neoplasms
25-hydroxy-vitamin d metabolism in human colon cancer cells during tumor progression.
Neoplasms
25-Hydroxyvitamin D-1 alpha-hydroxylase (CYP27B1) is a new class of tumor suppressor in the prostate.
Neoplasms
25-hydroxyvitamin D3-1alpha-hydroxylase expression in normal and malignant human colon.
Neoplasms
Additional clues for a protective role of vitamin d in neurodegenerative diseases: 1,25-dihydroxyvitamin d3 triggers an anti-inflammatory response in brain pericytes.
Neoplasms
Altered expression of the vitamin D metabolizing enzymes CYP27B1 and CYP24A1 under the context of prostate aging and pathologies.
Neoplasms
Analysis of CYP27B1, encoding 25-hydroxyvitamin D-1alpha-hydroxylase, as a candidate tumor suppressor gene in primary and severe secondary/tertiary hyperparathyroidism.
Neoplasms
Association of the vitamin D metabolism gene GC and CYP27B1 polymorphisms with cancer susceptibility: a meta-analysis and trial sequential analysis.
Neoplasms
Autocrine metabolism of vitamin D in normal and malignant breast tissue.
Neoplasms
Biological actions of extra-renal 25-hydroxyvitamin D-1alpha-hydroxylase and implications for chemoprevention and treatment.
Neoplasms
Chronic moderate ethanol intake differentially regulates vitamin D hydroxylases gene expression in kidneys and xenografted breast cancer cells in female mice.
Neoplasms
CYP24A1 and CYP27B1 Polymorphisms, Concentrations of Vitamin D Metabolites, and Odds of Colorectal Adenoma Recurrence.
Neoplasms
Decreased expression of CYP27B1 correlates with the increased aggressiveness of ovarian carcinomas.
Neoplasms
Dietary vitamin D? and 1,25-dihydroxyvitamin D? (calcitriol) exhibit equivalent anticancer activity in mouse xenograft models of breast and prostate cancer.
Neoplasms
Differential Expression of Prostaglandin I2 Synthase Associated with Arachidonic Acid Pathway in the Oral Squamous Cell Carcinoma.
Neoplasms
Endocrine actions of vitamin D in skin: Relevance for photocarcinogenesis of non-melanoma skin cancer, and beyond.
Neoplasms
Epigenetic regulation of vitamin D hydroxylase expression and activity in normal and malignant human prostate cells.
Neoplasms
Equivalent anticancer activities of dietary vitamin D and calcitriol in an animal model of breast cancer: Importance of mammary CYP27B1 for treatment and prevention.
Neoplasms
Expression analysis of CYP27B1 in tumor biopsies and cell cultures.
Neoplasms
Expression and activity of vitamin D-metabolizing cytochrome P450s (CYP1alpha and CYP24) in human nonsmall cell lung carcinomas.
Neoplasms
Expression of 25-hydroxyvitamin D-1-alpha-hydroxylase, and vitamin D receptor mRNA in normal and malignant breast tissue.
Neoplasms
Expression of CYP2R1 and VDR in human brain pericytes: the neurovascular vitamin D autocrine/paracrine model.
Neoplasms
Expression of the vitamin D receptor, 25-hydroxylases, 1alpha-hydroxylase and 24-hydroxylase in the human kidney and renal clear cell cancer.
Neoplasms
Expression of the vitamin D-activating enzyme 1?-hydroxylase (CYP27B1) decreases during melanoma progression.
Neoplasms
Expression of Vitamin D Receptor (VDR) Positively Correlates with Survival of Urothelial Bladder Cancer Patients.
Neoplasms
Expression of vitamin D receptor and 25-hydroxyvitamin D3-1{alpha}-hydroxylase in normal and malignant human colon.
Neoplasms
Expression of vitamin D receptor and metabolizing enzymes in multiple sclerosis-affected brain tissue.
Neoplasms
Extra-renal 25-hydroxyvitamin D3-1alpha-hydroxylase in human health and disease.
Neoplasms
Function of the vitamin D endocrine system in mammary gland and breast cancer.
Neoplasms
Gene expression of vitamin D metabolic enzymes at baseline and in response to vitamin D treatment in thyroid cancer cell lines.
Neoplasms
Gene expression profiles of CYP24A1 and CYP27B1 in malignant and normal breast tissues.
Neoplasms
Genetic polymorphisms in the vitamin D pathway in relation to lung cancer risk and survival.
Neoplasms
Genetic sequence variants in vitamin D metabolism pathway genes, serum vitamin D level and outcome in head and neck cancer patients.
Neoplasms
Genistein and 17beta-estradiol, but not equol, regulate vitamin D synthesis in human colon and breast cancer cells.
Neoplasms
Hemangiopericytoma-induced osteomalacia: tumor transplantation in nude mice causes hypophosphatemia and tumor extracts inhibit renal 25-hydroxyvitamin D 1-hydroxylase activity.
Neoplasms
Hepatocellular carcinoma cells express 25(OH)D-1?-hydroxylase and are able to convert 25(OH)D to 1?,25(OH)?D, leading to the 25(OH)D-induced growth inhibition.
Neoplasms
How would serum 25(OH)D level change in patients with inflammatory bowel disease depending on intestinal mucosa vitamin D receptor (VDR) and vitamin D1-? hydroxylase (CYP27B1)?
Neoplasms
Hypercalcemia in non-Hodgkin's lymphoma due to cosecretion of PTHrP and 1,25-dihydroxyvitamin D.
Neoplasms
Hypercalcemia of malignancy with simultaneous elevation in serum parathyroid hormone--related peptide and 1,25-dihydroxyvitamin d in a patient with metastatic renal cell carcinoma.
Neoplasms
Hypercalcemic hyperparathyroidism complicating oncogenic osteomalacia. Effect of successful tumor resection on mineral homeostasis.
Neoplasms
Identification of growth factor independent-1 (GFI1) as a repressor of 25-hydroxyvitamin D 1-alpha hydroxylase (CYP27B1) gene expression in human prostate cancer cells.
Neoplasms
Impact of vitamin D metabolism on clinical epigenetics.
Neoplasms
Increase in serum 1,25-dihydroxyvitamin D and hypercalcaemia in a patient with inflammatory myofibroblastic tumour.
Neoplasms
Increased expression of 25-hydroxyvitamin D-1alpha-hydroxylase in dysgerminomas: a novel form of humoral hypercalcemia of malignancy.
Neoplasms
Is Vitamin D Deficiency Related to Increased Cancer Risk in Patients with Type 2 Diabetes Mellitus?
Neoplasms
Losartan and Vitamin D Inhibit Colonic Tumor Development in a Conditional Apc-Deleted Mouse Model of Sporadic Colon Cancer.
Neoplasms
Metabolism of vitamin D in the human choriocarcinoma cell line JEG-3.
Neoplasms
Methotrexate-induced iatrogenic immunodeficiency-associated lymphoproliferative disorder causing hypercalcaemia.
Neoplasms
Modulation of vitamin D synthesis and catabolism in colorectal mucosa: a new target for cancer prevention.
Neoplasms
Nutritional regulation of extrarenal vitamin D hydroxylase expression - potential application in tumor prevention and therapy.
Neoplasms
On the relationship between VDR, ROR? and ROR? receptors expression and HIF1-? levels in human melanomas.
Neoplasms
Phosphaturic mesenchymal tumor, mixed connective tissue variant (oncogenic osteomalacia).
Neoplasms
Phytoestrogens and vitamin D metabolism: a new concept for the prevention and therapy of colorectal, prostate, and mammary carcinomas.
Neoplasms
Potentiating effects of nonactive/active vitamin D analogues and ketoconazole in parathyroid cells.
Neoplasms
Regulation of 25-hydroxyvitamin D-1alpha-hydroxylase by epidermal growth factor in prostate cells.
Neoplasms
Regulation of extrarenal synthesis of 1,25-dihydroxyvitamin D3--relevance for colonic cancer prevention and therapy.
Neoplasms
Regulation of extrarenal vitamin D metabolism as a tool for colon and prostate cancer prevention.
Neoplasms
Relative Expression of Vitamin D Hydroxylases, CYP27B1 and CYP24A1, and of Cyclooxygenase-2 and Heterogeneity of Human Colorectal Cancer in Relation to Age, Gender, Tumor Location, and Malignancy: Results from Factor and Cluster Analysis.
Neoplasms
Role of oncoprotein growth factor independent-1 (GFI1) in repression of 25-hydroxyvitamin D 1alpha-hydroxylase (CYP27B1): a comparative analysis in human prostate cancer and kidney cells.
Neoplasms
Targeted disruption of the 25-hydroxyvitamin D3 1alpha-hydroxylase gene in ras-transformed keratinocytes demonstrates that locally produced 1alpha,25-dihydroxyvitamin D3 suppresses growth and induces differentiation in an autocrine fashion.
Neoplasms
The Vitamin D endocrine system of the gut--its possible role in colorectal cancer prevention.
Neoplasms
The vitamin D receptor: a tumor suppressor in skin.
Neoplasms
Tumoral Vitamin D Synthesis by CYP27B1 1-?-Hydroxylase Delays Mammary Tumor Progression in the PyMT-MMTV Mouse Model and Its Action Involves NF-?B Modulation.
Neoplasms
Vitamin D Analogs Potentiate the Antitumor Effect of Imatinib Mesylate in a Human A549 Lung Tumor Model.
Neoplasms
Vitamin D autocrine system and prostate cancer.
Neoplasms
Vitamin D deficiency enhances the growth of MC-26 colon cancer xenografts in Balb/c mice.
Neoplasms
Vitamin D in normal and pathological parathyroid glands: new prospects for treating hyperparathyroidism (review).
Neoplasms
Vitamin D metabolism in mammary gland and breast cancer.
Neoplasms
Vitamin D Receptor Expression in Plasmablastic Lymphoma and Myeloma Cells Confers Susceptibility to Vitamin D.
Neoplasms
Vitamin D signaling and melanoma: role of vitamin D and its receptors in melanoma progression and management.
Neoplasms
[The influence of isoflavonoids on the antitumor activity of vitamin D3]
Neoplasms
[The role of phosphatonin in phosphate metabolism]
Neoplasms, Second Primary
Genetic sequence variants in vitamin D metabolism pathway genes, serum vitamin D level and outcome in head and neck cancer patients.
Nephrocalcinosis
1alpha-Hydroxylase gene ablation and Pi supplementation inhibit renal calcification in mice homozygous for the disrupted Npt2a gene.
Nephrogenic Fibrosing Dermopathy
Hypercalcemia and Overexpression of CYP27B1 in a Patient with Nephrogenic Systemic Fibrosis: Clinical Vignette and Literature Review.
Neuromyelitis Optica
Variants of CYP27B1 are associated with both multiple sclerosis and neuromyelitis optica patients in Han Chinese population.
Nevus
Expression of the vitamin D-activating enzyme 1?-hydroxylase (CYP27B1) decreases during melanoma progression.
Non-alcoholic Fatty Liver Disease
Association of vitamin D levels and vitamin D-related gene polymorphisms with liver fibrosis in patients with biopsy-proven nonalcoholic fatty liver disease.
Non-alcoholic Fatty Liver Disease
Genetic Polymorphism of Vitamin D Family Genes CYP2R1, CYP24A1, and CYP27B1 Are Associated With a High Risk of Non-alcoholic Fatty Liver Disease: A Case-Control Study.
Obesity
CYP27B1 as an instrument gene to investigate the causal relationship between vitamin D deficiency and obesity: a family-based study.
Obesity
Genetic association analysis of vitamin D pathway with obesity traits.
Obesity
Methylation Status of CYP27B1 and IGF2 Correlate to BMI SDS in Children with Obesity.
Obesity
Vitamin D pathway-related gene polymorphisms and their association with metabolic diseases: A literature review.
Obesity, Maternal
Role of pregnancy and obesity on vitamin D status, transport, and metabolism in baboons.
Osteomalacia
High dietary vitamin D prevents hypocalcemia and osteomalacia in CYP27B1 knockout mice.
Osteomalacia
Klotho gene, phosphocalcic metabolism, and survival in dialysis.
Osteomalacia
Saccharated ferric oxide-induced osteomalacia in Japan: iron-induced osteopathy due to nephropathy.
Osteomalacia
Vitamin D and bone.
Osteomalacia
[Rickets/osteomalacia revisited. Drug-induced osteomalacia.]
Osteoporosis, Postmenopausal
Effects of one-year treatment with estrogens on bone mass, intestinal calcium absorption, and 25-hydroxyvitamin D-1 alpha-hydroxylase reserve in postmenopausal osteoporosis.
Osteosarcoma
RNAi-mediated silencing of CYP27B1 abolishes 1,25(OH)2D3 synthesis and reduces osteocalcin and CYP24 mRNA expression in human osteosarcoma (HOS) cells.
Ovarian Neoplasms
Analysis of the vitamin D system in cervical carcinomas, breast cancer and ovarian cancer.
Ovarian Neoplasms
CYP27B1 Downregulation: A New Molecular Mechanism Regulating EZH2 in Ovarian Cancer Tumorigenicity.
Ovarian Neoplasms
Decreased expression of CYP27B1 correlates with the increased aggressiveness of ovarian carcinomas.
Ovarian Neoplasms
Role of 24-hydroxylase in vitamin D3 growth response of OVCAR-3 ovarian cancer cells.
Ovarian Neoplasms
Vitamin D-related genes, serum vitamin D concentrations and prostate cancer risk.
Pancreatic Neoplasms
Pancreatic cancer cells express 25-hydroxyvitamin D-1 alpha-hydroxylase and their proliferation is inhibited by the prohormone 25-hydroxyvitamin D3.
Pancreatic Neoplasms
Single Nucleotide Polymorphisms in 25-Hydroxyvitamin D3 1-Alpha-Hydroxylase (CYP27B1) Gene: The Risk of Malignant Tumors and Other Chronic Diseases.
Parathyroid Neoplasms
25-hydroxyvitamin D(3)-1alpha-hydroxylase expression in normal and pathological parathyroid glands.
Parathyroid Neoplasms
A Possible Link Between Parathyroid Hormone Secretion and Local Regulation of GABA in Human Parathyroid Adenomas.
Parathyroid Neoplasms
Analysis of CYP27B1, encoding 25-hydroxyvitamin D-1alpha-hydroxylase, as a candidate tumor suppressor gene in primary and severe secondary/tertiary hyperparathyroidism.
Parathyroid Neoplasms
Increased 25-hydroxyvitamin D3 1alpha-hydroxylase and reduced 25-hydroxyvitamin D3 24-hydroxylase expression in parathyroid tumors--new prospects for treatment of hyperparathyroidism with vitamin d.
Polycystic Kidney, Autosomal Dominant
Association of Vitamin D Levels With Kidney Volume in Autosomal Dominant Polycystic Kidney Disease (ADPKD).
Polymyositis
Rare Causes of Calcitriol-Mediated Hypercalcemia: A Case Report and Literature Review.
Pre-Eclampsia
First trimester vitamin D status and placental epigenomics in preeclampsia among Northern Plains primiparas.
Pre-Eclampsia
Maternal vitamin D status in preeclampsia: seasonal changes are not influenced by placental gene expression of vitamin D metabolizing enzymes.
Premature Birth
Lower placental 25-hydroxyvitamin D3 (25(OH)D3) and higher placental CYP27B1 and 25(OH)D3 ratio in preterm birth.
Prostatic Hyperplasia
25-Hydroxyvitamin D-1alpha-hydroxylase activity is diminished in human prostate cancer cells and is enhanced by gene transfer.
Prostatic Hyperplasia
Reduced 1alpha-hydroxylase activity in human prostate cancer cells correlates with decreased susceptibility to 25-hydroxyvitamin D3-induced growth inhibition.
Prostatic Hyperplasia
Vitamin D autocrine system and prostate cancer.
Prostatic Neoplasms
25-Hydroxyvitamin D-1 alpha-hydroxylase (CYP27B1) is a new class of tumor suppressor in the prostate.
Prostatic Neoplasms
25-Hydroxyvitamin D-1alpha-hydroxylase activity is diminished in human prostate cancer cells and is enhanced by gene transfer.
Prostatic Neoplasms
Comprehensive association analysis of the vitamin D pathway genes, VDR, CYP27B1, and CYP24A1, in prostate cancer.
Prostatic Neoplasms
Genistein inhibits vitamin D hydroxylases CYP24 and CYP27B1 expression in prostate cells.
Prostatic Neoplasms
Human prostate cells synthesize 1,25-dihydroxyvitamin D3 from 25-hydroxyvitamin D3.
Prostatic Neoplasms
Identification of growth factor independent-1 (GFI1) as a repressor of 25-hydroxyvitamin D 1-alpha hydroxylase (CYP27B1) gene expression in human prostate cancer cells.
Prostatic Neoplasms
Mechanisms of decreased Vitamin D 1alpha-hydroxylase activity in prostate cancer cells.
Prostatic Neoplasms
Prostatic 25-hydroxyvitamin D-1alpha-hydroxylase and its implication in prostate cancer.
Prostatic Neoplasms
Reduced 1alpha-hydroxylase activity in human prostate cancer cells correlates with decreased susceptibility to 25-hydroxyvitamin D3-induced growth inhibition.
Prostatic Neoplasms
Role of oncoprotein growth factor independent-1 (GFI1) in repression of 25-hydroxyvitamin D 1alpha-hydroxylase (CYP27B1): a comparative analysis in human prostate cancer and kidney cells.
Prostatic Neoplasms
Sequence variants in the human 25-hydroxyvitamin D3 1-alpha-hydroxylase (CYP27B1) gene are not associated with prostate cancer risk.
Prostatic Neoplasms
Single and multigenic analysis of the association between variants in 12 steroid hormone metabolism genes and risk of prostate cancer.
Prostatic Neoplasms
The prostate 25-hydroxyvitamin D-1 alpha-hydroxylase is not influenced by parathyroid hormone and calcium: implications for prostate cancer chemoprevention by vitamin D.
Prostatic Neoplasms
The roles of cytochrome P450 enzymes in prostate cancer development and treatment.
Prostatic Neoplasms
Vitamin D autocrine system and prostate cancer.
Prostatic Neoplasms
Vitamin D Pathway and Other Related Polymorphisms and Risk of Prostate Cancer: Results from the Prostate Cancer Prevention Trial.
Prostatic Neoplasms
Vitamin D-related genes, serum vitamin D concentrations and prostate cancer risk.
Proteinuria
Active vitamin D and its analogue, 22-oxacalcitriol, ameliorate puromycin aminonucleoside-induced nephrosis in rats.
Pseudoxanthoma Elasticum
Hypophosphatemic osteosclerosis, hyperostosis, and enthesopathy associated with novel homozygous mutations of DMP1 encoding dentin matrix protein 1 and SPP1 encoding osteopontin: The first digenic SIBLING protein osteopathy?
Psoriasis
Mast cells express CYP27A1 and CYP27B1 in epithelial skin cancers and psoriasis.
Pulmonary Fibrosis
Vitamin D deficiency exacerbates bleomycin-induced pulmonary fibrosis partially through aggravating TGF-?/Smad2/3-mediated epithelial-mesenchymal transition.
Renal Insufficiency
Calcium, phosphate, and vitamin D.
Renal Insufficiency
Constitutive expression of 25-hydroxyvitamin D3-1alpha-hydroxylase in a transformed human proximal tubule cell line: evidence for direct regulation of vitamin D metabolism by calcium.
Renal Insufficiency
Effect of dietary phosphorus on circulating concentrations of 1,25-dihydroxyvitamin D and immunoreactive parathyroid hormone in children with moderate renal insufficiency.
Renal Insufficiency
Management of disturbed calcium metabolism in uraemic patients: 1. Use of vitamin D metabolites.
Renal Insufficiency, Chronic
Chronic kidney disease and diabetes mellitus predict resistance to vitamin d replacement therapy.
Renal Insufficiency, Chronic
Dysregulation of renal vitamin D metabolism in the uremic rat.
Renal Insufficiency, Chronic
Expanding role for vitamin D in chronic kidney disease: importance of blood 25-OH-D levels and extra-renal 1alpha-hydroxylase in the classical and nonclassical actions of 1alpha,25-dihydroxyvitamin D(3).
Renal Insufficiency, Chronic
Vitamin D insufficiency and hyperparathyroidism in children with chronic kidney disease.
Renal Insufficiency, Chronic
Vitamin D-regulated osteocytic sclerostin and BMP2 modulate uremic extraskeletal calcification.
Respiratory Tract Infections
Human Metapneumovirus Infection Inhibits Cathelicidin Antimicrobial Peptide Expression in Human Macrophages.
Retrognathia
Parathyroid Hormone Gene and Genes Involved in the Maintenance of Vitamin D Levels Association with Mandibular Retrognathism.
Rickets
1alpha-Hydroxylase and the action of vitamin D.
Rickets
25-hydroxyvitamin D 1alpha-hydroxylase: structure of the mouse gene, chromosomal assignment, and developmental expression.
Rickets
A case of vitamin D hydroxylation-deficient rickets type 1A caused by 2 novel pathogenic variants in CYP27B1 gene.
Rickets
A Case of Vitamin-D-Dependent Rickets Type 1A with Normal 1,25-Dihydroxyvitamin D Caused by Two Novel Mutations of the CYP27B1 Gene.
Rickets
A novel compound mutation of CYP27B1 in a Chinese family with vitamin D-dependent rickets type 1A.
Rickets
A novel CYP27B1 mutation causes a feline vitamin D-dependent rickets type IA.
Rickets
A novel G102E mutation of CYP27B1 in a large family with vitamin D-dependent rickets type 1.
Rickets
A novel pathogenic mutation of the CYP27B1 gene in a patient with vitamin D-dependent rickets type 1: a case report.
Rickets
A novel splicing defect (IVS6+1G>T) in a patient with pseudovitamin D deficiency rickets.
Rickets
Absence of Calcitriol Causes Increased Lactational Bone Loss and Lower Milk Calcium but Does Not Impair Post-lactation Bone Recovery in Cyp27b1 Null Mice.
Rickets
Absence of renal 25-hydroxycholecalciferol-1-hydroxylase activity in a pig strain with vitamin D-dependent rickets.
Rickets
Case report: vitamin D-dependent rickets type 1 caused by a novel CYP27B1 mutation.
Rickets
Clinical and genetic analysis of patients with vitamin D-dependent rickets type 1A.
Rickets
Cloning of human 25-hydroxyvitamin D-1 alpha-hydroxylase and mutations causing vitamin D-dependent rickets type 1.
Rickets
Correction of the abnormal mineral ion homeostasis with a high-calcium, high-phosphorus, high-lactose diet rescues the PDDR phenotype of mice deficient for the 25-hydroxyvitamin D-1alpha-hydroxylase (CYP27B1).
Rickets
CYP27B1 null mice with LacZreporter gene display no 25-hydroxyvitamin D3-1alpha-hydroxylase promoter activity in the skin.
Rickets
Does Genotype-Phenotype Correlation Exist in Vitamin D-Dependent Rickets Type IA: Report of 13 New Cases and Review of the Literature.
Rickets
Effect of parathyroid hormone on cAMP and 1,25-dihydroxyvitamin D formation and renal handling of phosphate in vitamin D-dependent rickets.
Rickets
Enzymatic properties of human 25-hydroxyvitamin D3 1alpha-hydroxylase coexpression with adrenodoxin and NADPH-adrenodoxin reductase in Escherichia coli.
Rickets
Enzymes involved in the activation and inactivation of vitamin D.
Rickets
Genetic disorders of Vitamin D biosynthesis and degradation.
Rickets
Genetic models show that parathyroid hormone and 1,25-dihydroxyvitamin D3 play distinct and synergistic roles in postnatal mineral ion homeostasis and skeletal development.
Rickets
Genetic mutation in the human 25-hydroxyvitamin D3 1alpha-hydroxylase gene causes vitamin D-dependent rickets type I.
Rickets
Genetics of vitamin D 1alpha-hydroxylase deficiency in 17 families.
Rickets
Genetics of vitamin D biosynthesis and its disorders.
Rickets
Homology modeling of human 25-hydroxyvitamin D3 1alpha-hydroxylase (CYP27B1) based on the crystal structure of rabbit CYP2C5.
Rickets
Human 25-hydroxyvitamin D-1alpha-hydroxylase: cloning, mutations, and gene expression.
Rickets
Hypervitaminosis D mediates compensatory Ca2+ hyperabsorption in TRPV5 knockout mice.
Rickets
Hypophosphatemic osteosclerosis, hyperostosis, and enthesopathy associated with novel homozygous mutations of DMP1 encoding dentin matrix protein 1 and SPP1 encoding osteopontin: The first digenic SIBLING protein osteopathy?
Rickets
Identification of the amino acid residue of CYP27B1 responsible for binding of 25-hydroxyvitamin D3 whose mutation causes vitamin D-dependent rickets type 1.
Rickets
In vivo function of VDR in gene expression-VDR knock-out mice.
Rickets
Inactivating mutations in the 25-hydroxyvitamin D3 1alpha-hydroxylase gene in patients with pseudovitamin D-deficiency rickets.
Rickets
Long-term clinical outcome and the identification of homozygous CYP27B1 gene mutations in a patient with vitamin D hydroxylation-deficient rickets type 1A.
Rickets
Metabolism of vitamin D3 by cytochromes P450.
Rickets
Molecular Analysis of CYP27B1 Mutations in Vitamin D-Dependent Rickets Type 1A: c.590G > A (p.G197D) Missense Mutation Causes a RNA Splicing Error.
Rickets
Mutation of the CYP2R1 Vitamin D 25-Hydroxylase in a Saudi Arabian Family with Severe Vitamin D Deficiency.
Rickets
Mutation prediction by PolyPhen or functional assay, a detailed comparison of CYP27B1 missense mutations.
Rickets
Mutation update and long-term outcome after treatment with active vitamin D3 in Chinese patients with pseudovitamin D-deficiency rickets (PDDR).
Rickets
No enzyme activity of 25-hydroxyvitamin D3 1alpha-hydroxylase gene product in pseudovitamin D deficiency rickets, including that with mild clinical manifestation.
Rickets
No evidence for a role of rare CYP27B1 functional variations in multiple sclerosis.
Rickets
No evidence of association between mutant alleles of the CYP27B1 gene and multiple sclerosis.
Rickets
Novel Compound Heterozygous Mutations in the CYP27B1 Gene Lead to Pseudovitamin D-Deficient Rickets.
Rickets
Novel CYP27B1 Gene Mutations in Patients with Vitamin D-Dependent Rickets Type 1A.
Rickets
Novel gene mutations in patients with 1alpha-hydroxylase deficiency that confer partial enzyme activity in vitro.
Rickets
Novel mutations in the 1alpha-hydroxylase (P450c1) gene in three families with pseudovitamin D-deficiency rickets resulting in loss of functional enzyme activity in blood-derived macrophages.
Rickets
Pseudo vitamin D deficiency rickets in pigs: in vitro measurements of renal 25-hydroxycholecalciferol-1-hydroxylase activity.
Rickets
Pseudovitamin D deficiency rickets--a report from the Indian subcontinent.
Rickets
Regulation of the epithelial Ca2+ channels in small intestine as studied by quantitative mRNA detection.
Rickets
Rescue of the phenotype of CYP27B1 (1alpha-hydroxylase)-deficient mice.
Rickets
Rescue of the pseudo-vitamin D deficiency rickets phenotype of CYP27B1-deficient mice by treatment with 1,25-dihydroxyvitamin D3: biochemical, histomorphometric, and biomechanical analyses.
Rickets
Short- and Long-Term Outcome of Patients with Pseudo-Vitamin D Deficiency Rickets Treated with Calcitriol.
Rickets
Stronger bonds between 25-hydroxyvitamin D 1alpha-hydroxylase and pseudovitamin D-deficiency rickets.
Rickets
Structure-function analysis of CYP27B1 and CYP27A1. Studies on mutants from patients with vitamin D-dependent rickets type I (VDDR-I) and cerebrotendinous xanthomatosis (CTX).
Rickets
Targeted inactivation of the 25-hydroxyvitamin D(3)-1(alpha)-hydroxylase gene (CYP27B1) creates an animal model of pseudovitamin D-deficiency rickets.
Rickets
The 25-hydroxyvitamin D 1-alpha-hydroxylase gene maps to the pseudovitamin D-deficiency rickets (PDDR) disease locus.
Rickets
The first case of vitamin D dependent rickets type 1A from Uzbek population with a novel mutation.
Rickets
The genetics and clinical manifestations of patients with vitamin D dependent rickets type 1A.
Rickets
Two novel 1alpha-hydroxylase mutations in French-Canadians with vitamin D dependency rickets type I1.
Rickets
Vestibular dysfunction in vitamin D receptor mutant mice.
Rickets
Vitamin D 1alpha-hydroxylase gene mutations in patients with 1alpha-hydroxylase deficiency.
Rickets
Vitamin D 1alpha-hydroxylase knockout mice as a hereditary rickets animal model.
Rickets
Vitamin D and bone.
Rickets
Vitamin D dependent rickets, diagnostic and therapeutic difficulties: two case reports.
Rickets
Vitamin D-dependent rickets (VDDR) type 1: case series of two siblings with a CYP27B1 mutation and review of the literature.
Rickets
Vitamin D-dependent rickets as a possible risk factor for multiple sclerosis.
Rickets
Vitamin D-Dependent Rickets Type 1 Caused by Mutations in CYP27B1 Affecting Protein Interactions With Adrenodoxin.
Rickets
Vitamin D/dietary calcium deficiency rickets and pseudo-vitamin D deficiency rickets.
Rickets
[Genetic basis for skeletal disease. Hereditary rickets].
Rickets
[Long term follow up of a patient with type I vitamin D-dependent rickets].
Rickets
[Type 1 hypocalcemic pseudo-deficiency rickets caused by renal 25-hydroxycholecalciferol 1-hydroxylase deficiency (apropos of 1 case)]
Rickets
[Vitamin D dependency and vitamin D resistance]
Rickets, Hypophosphatemic
Pathogenic role of Fgf23 in Dmp1-null mice.
Sarcoidosis
Expression of 25-hydroxyvitamin D3-1alpha-hydroxylase in subcutaneous fat necrosis.
Sarcoidosis
Extrarenal expression of 25-hydroxyvitamin d(3)-1 alpha-hydroxylase.
Sarcoidosis
Genes and metabolic pathway of sarcoidosis: identification of key players and risk modifiers.
Sarcoidosis
Identification of 25-hydroxyvitamin D3 1alpha-hydroxylase gene expression in macrophages.
Sarcoidosis
Lack of association of immune-response-gene polymorphisms with susceptibility to sarcoidosis in Slovenian patients.
Skin Diseases
Expression of 25-hydroxyvitamin D3-1alpha-hydroxylase in subcutaneous fat necrosis.
Skin Diseases
Vitamin D-mediated hypercalcemia in slack skin disease: evidence for involvement of extrarenal 25-hydroxyvitamin D 1alpha-hydroxylase.
Skin Neoplasms
Endocrine actions of vitamin D in skin: Relevance for photocarcinogenesis of non-melanoma skin cancer, and beyond.
Skin Neoplasms
Mast cells express CYP27A1 and CYP27B1 in epithelial skin cancers and psoriasis.
Skin Neoplasms
Vitamin D enzymes (CYP27A1, CYP27B1, and CYP24A1) and receptor expression in non-melanoma skin cancer.
Spondylitis, Ankylosing
Polymorphisms in genetics of vitamin D metabolism confer susceptibility to ocular Behçet disease in a Chinese Han population.
Squamous Cell Carcinoma of Head and Neck
NNK-mediated upregulation of DEPDC1 stimulates the progression of oral squamous cell carcinoma by inhibiting CYP27B1 expression.
Squamous Cell Carcinoma of Head and Neck
Prognostic value of lipid metabolism-related genes in head and neck squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Vitamin D receptor, CYP27B1 and CYP24A1 genes polymorphisms association with oral cancer risk and survival.
Starvation
Hypergravity modulates vitamin D receptor target gene mRNA expression in mice.
Thyroid Carcinoma, Anaplastic
Altered expression of key players in vitamin D metabolism and signaling in malignant and benign thyroid tumors.
Thyroid Diseases
[Relevance of CYP27B1 gene promoter polymorphism to autoimmune thyroid diseases]
Thyroid Neoplasms
Altered expression of key players in vitamin D metabolism and signaling in malignant and benign thyroid tumors.
Thyroiditis
A promoter polymorphism of the CYP27B1 gene is associated with Addison's disease, Hashimoto's thyroiditis, Graves' disease and type 1 diabetes mellitus in Germans.
Thyroiditis
Low bone mineral density and renal malformation in Mexican patients with Turner syndrome are associated with single nucleotide variants in vitamin D-metabolism genes.
Thyroiditis
Vitamin D 1alpha-hydroxylase (CYP1alpha) polymorphism in Graves' disease, Hashimoto's thyroiditis and type 1 diabetes mellitus.
Thyroiditis, Autoimmune
[Vitamin D in the etiopathogenesis of autoimmune thyroiditis].
Tooth Resorption
Increased vitamin D-driven signalling and expression of the vitamin D receptor, MSX2, and RANKL in tooth resorption in cats.
Tuberculosis
In silico identification of novel transcription factors associated with CYP27B1 transcriptional regulation in LPS-challenged mononuclear phagocytes.
Tuberculosis
Role Of Vitamin-D Supplementation In TB/HIV Co-Infected Patients.
Uremia
Fibroblast Growth Factor 23 Regulation by Systemic and Local Osteoblast-Synthesized 1,25-Dihydroxyvitamin D.
Uremia
Uremia suppresses immune signal-induced CYP27B1 expression in human monocytes.
Ureteral Obstruction
Changes of renal vitamin D metabolic enzyme expression and calcium transporter abundance in obstructive nephropathy.
Urinary Bladder Neoplasms
Expression of Vitamin D Receptor (VDR) Positively Correlates with Survival of Urothelial Bladder Cancer Patients.
Uterine Cervical Neoplasms
Analysis of 25-hydroxyvitamin D3-1alpha-hydroxylase in cervical tissue.
Uterine Cervical Neoplasms
Calcitriol down-regulates human ether a go-go 1 potassium channel expression in cervical cancer cells.
Uveitis
Association between polymorphism of the vitamin D metabolism gene CYP27B1 and HLA-B27-associated uveitis. Is a state of relative immunodeficiency pathogenic in HLA B27-positive uveitis?
Uveitis
Polymorphisms in genetics of vitamin D metabolism confer susceptibility to ocular Behçet disease in a Chinese Han population.
Uveitis, Anterior
Polymorphisms in genetics of vitamin D metabolism confer susceptibility to ocular Behçet disease in a Chinese Han population.
Virus Diseases
Impact of CYP2R1, CYP27A1 and CYP27B1 genetic polymorphisms controlling vitamin D metabolism on susceptibility to hepatitis C virus infection in a high-risk Chinese population.
Virus Diseases
Vitamin D receptor, vitamin D binding protein and CYP27B1 single nucleotide polymorphisms and susceptibility to viral infections in infants.
Vitamin D Deficiency
1alpha,24(S)(OH)2D2 normalizes bone morphology and serum parathyroid hormone without hypercalcemia in 25-hydroxyvitamin D-1-hydroxylase (CYP27B1)-deficient mice, an animal model of vitamin D deficiency with secondary hyperparathyroidism.
Vitamin D Deficiency
Altered endocrine and autocrine metabolism of vitamin D in a mouse model of gastrointestinal inflammation.
Vitamin D Deficiency
Characterization of an animal model of pregnancy-induced vitamin D deficiency due to metabolic gene dysregulation.
Vitamin D Deficiency
Correction of the abnormal mineral ion homeostasis with a high-calcium, high-phosphorus, high-lactose diet rescues the PDDR phenotype of mice deficient for the 25-hydroxyvitamin D-1alpha-hydroxylase (CYP27B1).
Vitamin D Deficiency
CYP27B1 as an instrument gene to investigate the causal relationship between vitamin D deficiency and obesity: a family-based study.
Vitamin D Deficiency
Effects of Cholecalciferol on Key Components of Vitamin D-Endo/Para/Autocrine System in Experimental Type 1 Diabetes.
Vitamin D Deficiency
Family-based Association between Allele T of rs4646536 in CYP27B1 and vitamin D deficiency.
Vitamin D Deficiency
Gestational diabetes mellitus and vitamin D deficiency: genetic contribution of CYP27B1 and CYP2R1 polymorphisms.
Vitamin D Deficiency
Long-term vitamin D deficiency in older adult C57BL/6 mice does not affect bone structure, remodeling and mineralization.
Vitamin D Deficiency
Mutation of the CYP2R1 Vitamin D 25-Hydroxylase in a Saudi Arabian Family with Severe Vitamin D Deficiency.
Vitamin D Deficiency
Pseudo vitamin D deficiency rickets in pigs: in vitro measurements of renal 25-hydroxycholecalciferol-1-hydroxylase activity.
Vitamin D Deficiency
Rescue of the phenotype of CYP27B1 (1alpha-hydroxylase)-deficient mice.
Vitamin D Deficiency
Response of the 5'-flanking region of the human 25-hydroxyvitamin D 1alpha-hydroxylase gene to physiological stimuli using a transgenic mouse model.
Vitamin D Deficiency
Role of the vitamin D-endocrine system in the pathophysiology of postmenopausal osteoporosis.
Vitamin D Deficiency
Role of vitamin d in insulin resistance.
Vitamin D Deficiency
The deficiency and the supplementation of vitamin D and liver: Lessons of chronic fructose-rich diet in mice.
Vitamin D Deficiency
The prevalence of headache may be related with the latitude: a possible role of Vitamin D insufficiency?
Vitamin D Deficiency
Vitamin D and bone.
Vitamin D Deficiency
Vitamin D Deficiency in the Gulf Cooperation Council: Exploring the Triad of Genetic Predisposition, the Gut Microbiome and the Immune System.
Vitamin D Deficiency
Vitamin D status and gene transcription in immune cells.
Vitamin D Deficiency
[Association between vitamin D status and CYP27b1 and CYP24A1 gene polymorphisms in patients with multiple sclerosis in the Altai region].
Vitiligo
Association study between vitiligo and autoimmune-related genes CYP27B1, REL, TNFAIP3, IL2 and IL21.
Xanthomatosis
Structure-function analysis of CYP27B1 and CYP27A1. Studies on mutants from patients with vitamin D-dependent rickets type I (VDDR-I) and cerebrotendinous xanthomatosis (CTX).
Xanthomatosis, Cerebrotendinous
Structure-function analysis of CYP27B1 and CYP27A1. Studies on mutants from patients with vitamin D-dependent rickets type I (VDDR-I) and cerebrotendinous xanthomatosis (CTX).
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Delvin, E.E.; Arabian, A.
Kinetics and regulation of 25-hydroxycholecalciferol 1 alpha-hydroxylase from cells isolated from human term decidua
Eur. J. Biochem.
163
659-662
1987
Homo sapiens
brenda
Sawada, N.; Sakaki, T.; Kitanaka, S.; Takeyama, K.i.; Kato, S.; Inouye, K.
Enzymatic properties of human 25-hydroxyvitamin D3 1alpha-hydroxylase: coexpression with adrenodoxin and NADPH-adrenodoxin reductase in Escherichia coli
Eur. J. Biochem.
265
950-956
1999
Homo sapiens
brenda
Hagenfeldt, Y.; Berlin, T.
The human renal 25-hydroxyvitamin D3-1a-hydroxylase: properties studied by isotope-dilution mass spectrometry
Eur. J. Clin. Invest.
22
223-228
1992
Homo sapiens
brenda
Bareis, P.; Kallay, E.; Bischof, M.G.; Bises, G.; Hofer, H.; Potzi, C.; Manhardt, T.; Bland, R.; Cross, H.S.
Clonal differences in expression of 25-hydroxyvitamin D(3)-1alpha-hydroxylase, of 25-hydroxyvitamin D(3)-24-hydroxylase, and of the vitamin D receptor in human colon carcinoma cells: effects of epidermal growth factor and 1alpha,25-dihydroxyvitamin D(3)
Exp. Cell Res.
276
320-327
2002
Homo sapiens
brenda
Inouye, K.; Sakaki, T.
Enzymatic studies on the key enzymes of vitamin D metabolism; 1alpha-hydroxylase (CYP27B1) and 24-hydroxylase (CYP24)
Biotechnol. Annu. Rev.
7
179-194
2001
Homo sapiens, Mus musculus
brenda
Diaz, L.; Arranz, C.; Avila, E.; Halhali, A.; Vilchis, F.; Larrea, F.
Expression and activity of 25-hydroxyvitamin D-1alpha-hydroxylase are restricted in cultures of human syncytiotrophoblast cells from preeclamptic pregnancies
J. Clin. Endocrinol. Metab.
87
3876-3882
2002
Homo sapiens
brenda
Somjen, D.; Weisman, Y.; Kohen, F.; Gayer, B.; Limor, R.; Sharon, O.; Jaccard, N.; Knoll, E.; Stern, N.
25-Hydroxyvitamin D3-1alpha-hydroxylase is expressed in human vascular smooth muscle cells and is upregulated by parathyroid hormone and estrogenic compounds
Circulation
111
1666-1671
2005
Homo sapiens
brenda
Eyles, D.W.; Smith, S.; Kinobe, R.; Hewison, M.; McGrath, J.J.
Distribution of the vitamin D receptor and 1alpha-hydroxylase in human brain
J. Chem. Neuroanat.
29
21-30
2005
Homo sapiens
brenda
Diesel, B.; Seifert, M.; Radermacher, J.; Fischer, U.; Tilgen, W.; Reichrath, J.; Meese, E.
Towards a complete picture of splice variants of the gene for 25-hydroxyvitamin D3 1alpha-hydroxylase in brain and skin cancer
J. Steroid Biochem. Mol. Biol.
89-90
527-532
2004
Homo sapiens
brenda
Khorchide, M.; Lechner, D.; Cross, H.S.
Epigenetic regulation of vitamin D hydroxylase expression and activity in normal and malignant human prostate cells
J. Steroid Biochem. Mol. Biol.
93
167-172
2005
Homo sapiens
brenda
Ma, J.F.; Nonn, L.; Campbell, M.J.; Hewison, M.; Feldman, D.; Peehl, D.M.
Mechanisms of decreased Vitamin D 1alpha-hydroxylase activity in prostate cancer cells
Mol. Cell. Endocrinol.
221
67-74
2004
Homo sapiens
brenda
Friedrich, M.; Diesing, D.; Cordes, T.; Fischer, D.; Becker, S.; Chen, T.C.; Flanagan, J.N.; Tangpricha, V.; Gherson, I.; Holick, M.F.; Reichrath, J.
Analysis of 25-hydroxyvitamin D3-1alpha-hydroxylase in normal and malignant breast tissue
Anticancer Res.
26
2615-2620
2006
Homo sapiens
brenda
Segersten, U.; Holm, P.K.; Bjrklund, P.; Hessman, O.; Nordgren, H.; Binderup, L.; Akerstrm, G.; Hellman, P.; Westin, G.
25-Hydroxyvitamin D3 1alpha-hydroxylase expression in breast cancer and use of non-1alpha-hydroxylated vitamin D analogue
Breast Cancer Res.
7
R980-R986
2005
Homo sapiens (O15528)
brenda
Matusiak, D.; Murillo, G.; Carroll, R.E.; Mehta, R.G.; Benya, R.V.
Expression of vitamin D receptor and 25-hydroxyvitamin D3-1{alpha}-hydroxylase in normal and malignant human colon
Cancer Epidemiol. Biomarkers Prev.
14
2370-2376
2005
Homo sapiens
brenda
Kallay, E.; Bises, G.; Bajna, E.; Bieglmayer, C.; Gerdenitsch, W.; Steffan, I.; Kato, S.; Armbrecht, H.J.; Cross, H.S.
Colon-specific regulation of vitamin D hydroxylases - a possible approach for tumor prevention
Carcinogenesis
26
1581-1589
2005
Homo sapiens
brenda
Stoffels, K.; Overbergh, L.; Giulietti, A.; Verlinden, L.; Bouillon, R.; Mathieu, C.
Immune regulation of 25-hydroxyvitamin-D3-1alpha-hydroxylase in human monocytes
J. Bone Miner. Res.
21
37-47
2006
Homo sapiens
brenda
Overbergh, L.; Stoffels, K.; Waer, M.; Verstuyf, A.; Bouillon, R.; Mathieu, C.
Immune regulation of 25-hydroxyvitamin D-1alpha-hydroxylase in human monocytic THP1 cells: mechanisms of interferon-gamma-mediated induction
J. Clin. Endocrinol. Metab.
91
3566-3574
2006
Homo sapiens (O15528), Homo sapiens
brenda
Khadzkou, K.; Buchwald, P.; Westin, G.; Dralle, H.; Akerstroem, G.; Hellman, P.
25-hydroxyvitamin D3 1alpha-hydroxylase and vitamin D receptor expression in papillary thyroid carcinoma
J. Histochem. Cytochem.
54
355-361
2006
Homo sapiens
brenda
Hendrix, I.; Anderson, P.H.; Omdahl, J.L.; May, B.K.; Morris, H.A.
Response of the 5-flanking region of the human 25-hydroxyvitamin D 1alpha-hydroxylase gene to physiological stimuli using a transgenic mouse model
J. Mol. Endocrinol.
34
237-245
2005
Homo sapiens
brenda
Carneiro de Lyra, E.; Amorim da Silva, I.; Katayama, M.L.; Brentani, M.M.; Nonogaki, S.; Goes, J.C.; Folgueira, M.A.
25(OH)D3 and 1,25(OH)2D3 serum concentration and breast tissue expression of 1alpha-hydroxylase, 24-hydroxylase and Vitamin D receptor in women with and without breast cancer
J. Steroid Biochem. Mol. Biol.
100
184-192
2006
Homo sapiens
brenda
Townsend, K.; Evans, K.N.; Campbell, M.J.; Colston, K.W.; Adams, J.S.; Hewison, M.
Biological actions of extra-renal 25-hydroxyvitamin D-1alpha-hydroxylase and implications for chemoprevention and treatment
J. Steroid Biochem. Mol. Biol.
97
103-109
2005
Homo sapiens
brenda
Schroeder, O.; Turak, S.; Daniel, C.; Gaschott, T.; Stein, J.
Upregulation of 25-hydroxyvitamin D3-1alpha-hydroxylase by butyrate in Caco-2 cells
World J. Gastroenterol.
11
7136-7141
2005
Homo sapiens
brenda
Wang, L.; Persons, K.S.; Jamieson, D.; Flanagan, J.N.; Hsu, H.H.; Holick, M.F.; Luo, Z.; Sakaki, T.; Urushino, N.; Faller, D.V.; Chen, T.C.
Prostate 25-hydroxyvitamin D-1alpha-hydroxylase is up-regulated by suberoylanilide hydroxamic acid (SAHA), a histone deacetylase inhibitor
Anticancer Res.
28
2009-2013
2008
Homo sapiens
brenda
Chen, T.C.
25-Hydroxyvitamin D-1 alpha-hydroxylase (CYP27B1) is a new class of tumor suppressor in the prostate
Anticancer Res.
28
2015-2017
2008
Homo sapiens
brenda
Fischer, D.; Seifert, M.; Becker, S.; Ludders, D.; Cordes, T.; Reichrath, J.; Friedrich, M.
25-Hydroxyvitamin D3 1alpha-hydroxylase splice variants in breast cell lines MCF-7 and MCF-10
Cancer Genomics Proteomics
4
295-300
2007
Homo sapiens
brenda
Wu, S.; Ren, S.; Nguyen, L.; Adams, J.S.; Hewison, M.
Splice variants of the CYP27b1 gene and the regulation of 1,25-dihydroxyvitamin D3 production
Endocrinology
148
3410-3418
2007
Homo sapiens
brenda
Hewison, M.; Burke, F.; Evans, K.N.; Lammas, D.A.; Sansom, D.M.; Liu, P.; Modlin, R.L.; Adams, J.S.
Extra-renal 25-hydroxyvitamin D3-1alpha-hydroxylase in human health and disease
J. Steroid Biochem. Mol. Biol.
103
316-321
2007
Homo sapiens
brenda
Somjen, D.; Katzburg, S.; Stern, N.; Kohen, F.; Sharon, O.; Limor, R.; Jaccard, N.; Hendel, D.; Weisman, Y.
25 hydroxy-vitamin D(3)-1alpha hydroxylase expression and activity in cultured human osteoblasts and their modulation by parathyroid hormone, estrogenic compounds and dihydrotestosterone
J. Steroid Biochem. Mol. Biol.
107
238-244
2007
Homo sapiens
brenda
McCarthy, K.; Laban, C.; Bustin, S.A.; Ogunkolade, W.; Khalaf, S.; Carpenter, R.; Jenkins, P.J.
Expression of 25-hydroxyvitamin D-1-alpha-hydroxylase, and vitamin D receptor mRNA in normal and malignant breast tissue
Anticancer Res.
29
155-157
2009
Homo sapiens
brenda
Fischer, D.; Thome, M.; Becker, S.; Cordes, T.; Diedrich, K.; Friedrich, M.; Thill, M.
25-Hydroxyvitamin D3 1alpha-hydroxylase splice variants in benign and malignant ovarian cell lines and tissue
Anticancer Res.
29
3627-3633
2009
Homo sapiens
brenda
Fischer, D.; Becker, S.; Cordes, T.; Buecker, B.; Diedrich, K.; Friedrich, M.; Salehin, D.; Thill, M.
Vitamin D-24-hydroxylase in benign and malignant breast tissue and cell lines
Anticancer Res.
29
3641-3645
2009
Homo sapiens
brenda
Seifert, M.; Tilgen, W.; Reichrath, J.
Expression of 25-hydroxyvitamin D-1alpha-hydroxylase (1alphaOHase, CYP27B1) splice variants in HaCaT keratinocytes and other skin cells: modulation by culture conditions and UV-B treatment in vitro
Anticancer Res.
29
3659-3667
2009
Homo sapiens
brenda
Cross, H.S.; Nittke, T.; Peterlik, M.
Modulation of vitamin D synthesis and catabolism in colorectal mucosa: a new target for cancer prevention
Anticancer Res.
29
3705-3712
2009
Homo sapiens
brenda
Farooque, A.; Moss, C.; Zehnder, D.; Hewison, M.; Shaw, N.J.
Expression of 25-hydroxyvitamin D3-1alpha-hydroxylase in subcutaneous fat necrosis
Br. J. Dermatol.
160
423-425
2009
Homo sapiens
brenda
Novakovic, B.; Sibson, M.; Ng, H.K.; Manuelpillai, U.; Rakyan, V.; Down, T.; Beck, S.; Fournier, T.; Evain-Brion, D.; Dimitriadis, E.; Craig, J.M.; Morley, R.; Saffery, R.
Placenta-specific methylation of the vitamin D 24-hydroxylase gene: implications for feedback autoregulation of active vitamin D levels at the fetomaternal interface
J. Biol. Chem.
284
14838-14848
2009
Homo sapiens
brenda
Lauter, K.; Arnold, A.
Analysis of CYP27B1, encoding 25-hydroxyvitamin D-1alpha-hydroxylase, as a candidate tumor suppressor gene in primary and severe secondary/tertiary hyperparathyroidism
J. Bone Miner. Res.
24
102-104
2009
Homo sapiens
brenda
Dhawan, P.; Christakos, S.
Novel regulation of 25-hydroxyvitamin D3 24-hydroxylase (24(OH)ase) transcription by glucocorticoids: cooperative effects of the glucocorticoid receptor, C/EBP beta, and the vitamin D receptor in 24(OH)ase transcription
J. Cell. Biochem.
110
1314-1323
2010
Homo sapiens
brenda
Lagishetty, V.; Chun, R.F.; Liu, N.Q.; Lisse, T.S.; Adams, J.S.; Hewison, M.
1alpha-hydroxylase and innate immune responses to 25-hydroxyvitamin D in colonic cell lines
J. Steroid Biochem. Mol. Biol.
121
228-233
2010
Homo sapiens
brenda
Urbschat, A.; Paulus, P.; von Quernheim, Q.F.; Brueck, P.; Badenhoop, K.; Zeuzem, S.; Ramos-Lopez, E.
Vitamin D hydroxylases CYP2R1, CYP27B1 and CYP24A1 in renal cell carcinoma
Eur. J. Clin. Invest.
43
1282-1290
2013
Homo sapiens
brenda
Ritter, C.S.; Haughey, B.H.; Armbrecht, H.J.; Brown, A.J.
Distribution and regulation of the 25-hydroxyvitamin D3 1alpha-hydroxylase in human parathyroid glands
J. Steroid Biochem. Mol. Biol.
130
73-80
2012
Homo sapiens
brenda
1.14.15.18 calcidiol 1-monooxygenase
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The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable). 
