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Information on EC 1.14.14.53 - (R)-limonene 6-monooxygenase and Organism(s) Homo sapiens

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EC Tree
IUBMB Comments
The reaction is stereospecific with over 95% yield of (+)-trans-carveol from (R)-limonene. (S)-Limonene, the substrate for EC 1.14.14.51, (S)-limonene 6-monooxygenase, is not a substrate. Forms part of the carvone biosynthesis pathway in Carum carvi (caraway) seeds.
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This record set is specific for:
Homo sapiens
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The taxonomic range for the selected organisms is: Homo sapiens
The enzyme appears in selected viruses and cellular organisms
Synonyms
(+)-limonene 6-monooxygenase, (+)-limonene,NADPH:oxygen oxidoreductase (6-hydroxylating), (+)-limonene-6-hydroxylase, (R)-limonene,NADPH:oxygen oxidoreductase (6-hydroxylating), EC 1.14.13.80, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
(+)-limonene 6-monooxygenase
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(+)-limonene,NADPH:oxygen oxidoreductase (6-hydroxylating)
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(+)-limonene-6-hydroxylase
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(R)-limonene,NADPH:oxygen oxidoreductase (6-hydroxylating)
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
oxidation
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redox reaction
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reduction
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SYSTEMATIC NAME
IUBMB Comments
(R)-limonene,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase (6-hydroxylating)
The reaction is stereospecific with over 95% yield of (+)-trans-carveol from (R)-limonene. (S)-Limonene, the substrate for EC 1.14.14.51, (S)-limonene 6-monooxygenase, is not a substrate. Forms part of the carvone biosynthesis pathway in Carum carvi (caraway) seeds.
CAS REGISTRY NUMBER
COMMENTARY hide
221461-49-0
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UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
CP2C9_HUMAN
490
0
55628
Swiss-Prot
Secretory Pathway (Reliability: 1)
CP2CJ_HUMAN
490
0
55945
Swiss-Prot
Secretory Pathway (Reliability: 1)
CP2C9_HUMAN
490
0
55628
Swiss-Prot
-
CP2CJ_HUMAN
490
0
55945
Swiss-Prot
Mitochondrion (Reliability: 4)