Reference on EC 1.1.3.6 - cholesterol oxidase
Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Smith, A.G.; Brooks, C.J.W.
The substrate specificity and stereochemistry, reversibility and inhibition of the 3-oxo steroid DELTA 4-DELTA 5-isomerase component of cholesterol oxidase
Biochem. J.
167
121-129
1977
Nocardia erythropolis
Cheetham, P.S.J.; Dunnill, P.; Lilly, M.D.
The characterization and interconversion of three forms of cholesterol oxidase extracted from Nocardia rhodochrous
Biochem. J.
201
515-521
1982
Nocardia rhodochrous
Arima, K.; Nagasawa, M.; Bae, M.; Tamura, G.
Microbiol transformation of steroids. Part I. Decomposition of cholesterol by micro-organisms
Agric. Biol. Chem.
33
1636-1643
1969
Pimelobacter simplex
-
Smith, A.G.; Brooks, C.J.W.
Application of cholesterol oxidase in the analysis of steroids
J. Chromatogr.
101
373-378
1974
Nocardia erythropolis
Buckland, B.C.; Richmond, W.; Dunnill, P.; Lilly, M.D.
The large scale isolation of intrcellular microbial enzymes: cholesterol oxidase from Nocardia
Industrial Aspects of Biochemistry (Spencer, B. , ed. ) FEBS Amsterdam
2
65-79
1974
Nocardia rhodochrous
-
Uwajima, T.; Yagi, H.; Terado, O.
Properties of crystalline 3beta-hydroxysteroid oxidase of Brevibacterium sterolicum
Agric. Biol. Chem.
38
1149-1156
1974
Brevibacterium sterolicum
-
Tomioka, H.; Kagawa, M.; Nakamura, S.
Some enzymatic properties of 3beta-hydroxysteroid oxidase produced by Streptomyces violascens
J. Biochem.
79
903-915
1976
Streptomyces violascens
Petrova, L.Y.; Podsukhina, G.M.; Dikun, T.A.; Seleznava, A.A.
Conditions for isolation of cholesterol oxidase from Actinomyces lavendulae mycelia
Appl. Biochem. Microbiol.
15
125-144
1979
Streptomyces lavendulae
-
Shirokane, J.; Nakamura, K.; Mizusawa, K.
Purification and some properties of an extracellular 3-hydroxysteroid oxidase produced by Corynebacterium cholesterolicum
J. Ferment. Technol.
55
337-346
1977
Corynebacterium cholesterolicum
-
Smith, A.G.; Brooks, C.J.W.
Studies of the substrate specificity of cholesterol oxidase from Nocardia erythropolis in the oxidation of 3-hydroxy steroids
Biochem. Soc. Trans.
3
675-677
1975
Nocardia erythropolis
Fukuda, H.; Kawakami, Y.; Nakamura, S.
A method to screen anticholesterol substances produced by microbes and a new cholesterol oxidase produced by Streptomyces violascens
Chem. Pharm. Bull.
21
2057-2060
1973
Streptomyces violascens
Abe, T.; Nihira, T.; Tanaka, A.; Fukui, S.
Influence of long-chain primary alcohols on cholesterol oxidase from Schizophyllum commune
Biochim. Biophys. Acta
749
69-76
1983
Schizophyllum commune
-
Yoshimoto, T.; Ritani, A.; Ohwada, K.; Takahashi, K.; Kodera, Y.; Matsushima, A.; Saito, Y.; Inada, Y.
Polyethylene glycol derivative-modified cholesterol oxidase soluble and active in benzene
Biochem. Biophys. Res. Commun.
148
876-882
1987
Nocardia sp.
Uwajima, T.; Terada, O.
On the kinetics of cholesterol oxidase from Brevibacterium sterolicum in the presence of detergents
Agric. Biol. Chem.
42
1453-1454
1978
Brevibacterium sterolicum
-
Fukuyama, M.; Miyake, Y.
Purification and some properties of cholesterol oxidase from Schizophyllum commune with covalently bound flavin
J. Biochem.
85
1183-1193
1979
Schizophyllum commune
Liu, W.H.; Meng, M.H.; Chen, K.S.
Purification and some properties of cholesterol oxidases produced by an inducible and a constitutive mutant of Arthrobacter simplex
Agric. Biol. Chem.
52
413-418
1988
Pimelobacter simplex
-
Lee, S.; Rhee, H.; Tae, W.; Shin, J.; Park, B.
Purification and characterization of cholesterol oxidase from Pseudomonas sp. and taxonomic study of the strain
Appl. Microbiol. Biotechnol.
31
542-546
1989
Pseudomonas sp.
-
Cheillan, F.; Lafont, H.; Termine, E.; Fernandez, F.; Sauve, P.; Lesgards, G.
Molecular characteristics of the cholesterol oxidase and factors influencing its activity
Biochim. Biophys. Acta
999
233-238
1989
Pseudomonas sp.
-
Bru, R.; Sanchez-Ferrer, A.; Garcia-Carmona, F.
Characterization of cholesterol oxidase activity in AOT-isooctane reverse micelles and its dependence on micelle size
Biotechnol. Lett.
11
237-242
1989
Nocardia erythropolis
-
Johnson, T.L.; Somkuti, G.A.
Isolation of cholesterol oxidases from Rhodococcus equi ATCC 33706
Biotechnol. Appl. Biochem.
13
196-204
1991
Rhodococcus equi
-
Uwajima, T.; Yagi, H.; Nakamura, S.; Terada, O.
Isolation and crystallization of extracellular 3beta-hydroxysteroid oxidase of Brevibacterium sterolicum nov. Sp.
Agric. Biol. Chem.
37
2345-2350
1973
Brevibacterium sterolicum
-
Brooks, C.J.W.; Smith, A.G.
Cholesterol oxidase. Further studies of substrate specificity in relation to the analytical characterisation of steroids
J. Chromatogr.
112
499-511
1975
Nocardia erythropolis
Smith, A.G.; Brooks, C.J.W.
Cholesterol oxidases: properties and applications
J. Steroid Biochem.
7
705-713
1976
Streptomyces violascens, Brevibacterium sterolicum, Nocardia erythropolis
Stadman, T.C.; Cherkes, A.; Anfinsen, C.B.
Studies on the microbiological degradation of cholesterol
J. Biol. Chem.
206
511-523
1953
Mycobacterium sp.
Li, J.; Vrielink, A.; Brick, P.; Blow, D.M.
Crystal structure of cholesterol oxidase complexed with a steroid substrate: implications for flavin adenine dinucleotide dependent alcohol oxidases
Biochemistry
32
11507-11515
1993
Brevibacterium sterolicum
Croteau, N.; Vrielink, A.
Crystallization and preliminary x-ray analysis of cholesterol oxidase from Brevibacterium sterolicum containing covalently bound FAD
J. Struct. Biol.
116
317-319
1996
Brevibacterium sterolicum
Nishiya, Y.; Harada, N.; Teshima, S-i.; Yamahita, M.; Fuji, I.; Hirayama, N.; Murooka, Y.
Improvement of thermal stability of Streptomyces cholesterol oxidase by random mutagenesis and a structural interpretation
Protein Eng.
10
231-235
1997
Streptomyces sp.
Gadda, G.; Wels, G.; Pollegioni, L.; Zucchelli, S.; Amrosius, D.; Pilone, M.S.; Ghisla, S.
Characterization of cholesterol oxidase from Streptomyces hygroscopicus and Brevibacterium sterolicum
Eur. J. Biochem.
250
369-376
1997
Brevibacterium sterolicum, Streptomyces hygroscopicus
Sojo, M.; Bru, R.; Lopez-Molina, D.; Garcia-Carmona, F.; Arguelles, J.C.
Cell-linked and extracellular cholesterol oxidase activities from Rhodococcus erythropolis. Isolation and physiological characterization
Appl. Microbiol. Biotechnol.
47
583-589
1997
Nocardia rhodochrous, Rhodococcus erythropolis
Kimberley Yue, Q.; Kass, I.J.; Sampson, N.S.; Vrielink, A.
Crystal structure determination of cholesterol oxidase from Streptomyces and structural characterization of key active site mutants
Biochemistry
38
4277-4286
1999
Streptomyces sp. (P12676)
Pollegioni, L.; Gadda, G.; Ambrosius, D.; Ghisla, S.; Pilone, M.S.
Cholesterol oxidase from Streptomyces hycroscopicus and Brevibacterium sterolicum: effect of surfactants and organic solvents on activity
Biotechnol. Appl. Biochem.
30
27-33
1999
Brevibacterium sterolicum, Streptomyces hygroscopicus
Pollegioni, L.; Wels, G.; Pilone, M.S.; Ghisla, S.
Kinetic mechanisms of cholesterol oxidase from Streptomyces hygroscopicus and Brevibacterium sterolicum
Eur. J. Biochem.
264
140-151
1999
Brevibacterium sterolicum, Streptomyces hygroscopicus
MacLachlan, J.; Wotherspoon, A.T.L.; Ansell, R.O.; Brooks, C.J.W.
Cholesterol oxidase: sources, physical properties and analytical applications
J. Steroid Biochem. Mol. Biol.
72
169-195
2000
Brevibacterium sterolicum, Comamonas testosteroni, Corynebacterium cholesterolicum, Mycobacterium sp., Nocardia erythropolis, Nocardia rhodochrous, Nocardia sp., Pimelobacter simplex, Pseudomonas sp., Rhodococcus equi, Rhodococcus erythropolis, Rhodococcus sp., Rhodococcus sp. GK1, Schizophyllum commune, Streptomyces griseocarneus, Streptomyces hygroscopicus, Streptomyces lavendulae, Streptomyces lividans, Streptomyces sp., Streptomyces violascens
Motteront, L.; Pilonet, M.S.; Molla, G.; Ghisla, S.; Pollegioni, L.
Cholesterol oxidase from Brevibacterium sterolicum
J. Biol. Chem.
276
18024-18030
2001
Brevibacterium sterolicum
Doukyu, N.; Aono, R.
Cloning, sequence analysis and expression of a gene encoding an organic solvent- and detergent-tolerant cholesterol oxidase of Burkholderia cepacia strain ST-200
Appl. Microbiol. Biotechnol.
57
146-152
2001
Brevibacterium sterolicum, Burkholderia cepacia, Streptomyces sp., Nocardia erythropolis, Pseudomonas sp., Burkholderia cepacia ST-200
Ghoshroy, K.B.; Zhu, W.; Sampson, N.S.
Investigation of membrane disruption in the reaction catalyzed by cholesterol oxidase
Biochemistry
36
6133-6140
1997
Streptomyces sp., Streptomyces sp. A19249
Doukyu, N.; Aono, R.
Purification of extracellular cholesterol oxidase with high activity in the presence of organic solvents from Pseudomonas sp. strain ST-200
Appl. Environ. Microbiol.
64
1929-1932
1998
Pseudomonas sp., Pseudomonas sp. ST-200
Kerenyi, G.; Szentirmai, A.; Natonek, M.
Properties of delta5-3beta-hydroxysteroid oxidoreductase isolated from Streptomyces griseocarneus
Acta Microbiol. Acad. Sci. Hung.
22
487-496
1975
Streptomyces griseocarneus
Aunpad, R.; Muench, S.P.; Baker, P.J.; Sedelnikova, S.; Panbangred, W.; Doukyu, N.; Aono, R.; Rice, D.W.
Crystallization and preliminary X-ray crystallographic studies on the class II cholesterol oxidase from Burkholderia cepacia containing bound flavin
Acta Crystallogr. Sect. D
58
2182-2183
2002
Burkholderia cepacia
Bokoch, M.P.; Devadoss, A.; Palencsar, M.S.; Burgess, J.D.
Steady-state oxidation of cholesterol catalyzed by cholesterol oxidase in lipid bilayer membranes on platinum electrodes
Anal. Chim. Acta
519
47-55
2004
Pseudomonas sp.
-
Yin, Y.; Liu, P.; Anderson, R.G.; Sampson, N.S.
Construction of a catalytically inactive cholesterol oxidase mutant: investigation of the interplay between active site-residues glutamate 361 and histidine 447
Arch. Biochem. Biophys.
402
235-242
2002
Streptomyces sp.
Rhee, C.H.; Kim, K.P.; Park, H.D.
Two novel extracellular cholesterol oxidases of Bacillus sp. isolated from fermented flatfish
Biotechnol. Lett.
24
1385-1389
2002
Bacillus sp. (in: Bacteria), Bacillus sp. (in: Bacteria) SFF34
Lin, C.C.; Yang, M.C.
Cholesterol oxidation using hollow fiber dialyzer immobilized with cholesterol oxidase: preparation and properties
Biotechnol. Prog.
19
361-364
2003
Pseudomonas sp.
Sojo, M.M.; Bru, R.R.; Garcia-Carmona, F.F.
Rhodococcus erythropolis ATCC 25544 as a suitable source of cholesterol oxidase: cell-linked and extracellular enzyme synthesis, purification and concentration
BMC Biotechnol.
2
3
2002
Rhodococcus erythropolis
Fujishiro, K.; Uchida, H.; Shimokawa, K.; Nakano, M.; Sano, F.; Ohta, T.; Kayahara, N.; Aisaka, K.; Uwajima, T.
Purification and properties of a new Brevibacterium sterolicum cholesterol oxidase produced by E. coli MM294/pnH10
FEMS Microbiol. Lett.
215
243-248
2002
Brevibacterium sterolicum
Isobe, K.; Shoji, K.; Nakanishi, Y.; Yokoe, M.; Wakao, N.
Purification and some properties of cholesterol oxidase stable in detergents from gamma-Proteobacterium Y-134
J. Biosci. Bioeng.
95
257-263
2003
gamma proteobacterium Y-134
Isobe, K.; Mori, N.; Wakao, N.
The second cholesterol oxidase produced by gamma-Proteobacterium Y-134
J. Biosci. Bioeng.
96
257-261
2003
gamma proteobacterium Y-134
Lario, P.I.; Sampson, N.; Vrielink, A.
Sub-atomic resolution crystal structure of cholesterol oxidase: what atomic resolution crystallography reveals about enzyme mechanism and the role of the FAD cofactor in redox activity
J. Mol. Biol.
326
1635-1650
2003
Streptomyces sp. (P12676)
Toyama, M.; Yamashita, M.; Yoneda, M.; Zaborowski, A.; Nagato, M.; Ono, H.; Hirayama, N.; Murooka, Y.
Alteration of substrate specificity of cholesterol oxidase from Streptomyces sp. by site-directed mutagenesis
Protein Eng.
15
477-484
2002
Streptomyces sp.
Basu, A.K.; Chattopadhyay, P.; Roychoudhuri, U.; Chakraborty, R.
Development of cholesterol biosensor based on immobilized cholesterol esterase and cholesterol oxidase on oxygen electrode for the determination of total cholesterol in food samples
Bioelectrochemistry
70
375-379
2006
Brevibacterium sterolicum
Srisawasdi, P.; Jearanaikoon, P.; Wetprasit, N.; Sriwanthana, B.; Kroll, M.H.; Lolekha, P.H.
Application of Streptomyces and Brevibacterium cholesterol oxidase for total serum cholesterol assay by the enzymatic kinetic method
Clin. Chim. Acta
372
103-111
2006
Brevibacterium sp., Streptomyces sp.
Chen, Y.; Huang, H.; Cheng, Y.; Tang, T.; Liu, W.
Expression of a cholesterol oxidase gene from Arthrobacter simplex in Escherichia coli and Pichia pastoris
Enzyme Microb. Technol.
39
854-860
2006
Pimelobacter simplex (Q56DL0), Pimelobacter simplex F2 (Q56DL0)
-
Caldinelli, L.; Iametti, S.; Barbiroli, A.; Bonomi, F.; Fessas, D.; Molla, G.; Pilone, M.S.; Pollegioni, L.
Dissecting the structural determinants of the stability of cholesterol oxidase containing covalently bound flavin
J. Biol. Chem.
280
22572-22581
2005
Brevibacterium sterolicum
Singh, S.; Singhal, R.; Malhotra, B.D.
Immobilization of cholesterol esterase and cholesterol oxidase onto sol-gel films for application to cholesterol biosensor
Anal. Chim. Acta
582
335-343
2007
Pseudomonas sp.
Mahmoud, A.E.; Abdou, H.M.; Jwanny, E.W.
Extracellular Pleurotus ostreatus cholesterol oxidase. Purification and characterization
Adv. Food Sci.
29
12-20
2007
Pleurotus ostreatus
-
Hejazi, M.S.; Tabar, K.K.; Azarbaijani, R.; Nobar, L.Z.
Cloning and sequencing of partial segment of cholesterol oxidase encoding gene from Streptomyces luridus
Ann. Microbiol.
57
259-263
2007
Streptomyces luridus (Q1HKZ6)
-
Doukyu, N.; Shibata, K.; Ogino, H.; Sagermann, M.
Purification and characterization of Chromobacterium sp. DS-1 cholesterol oxidase with thermal, organic solvent, and detergent tolerance
Appl. Microbiol. Biotechnol.
80
59-70
2008
Chromobacterium sp. DS-1
Chen, L.; Lyubimov, A.Y.; Brammer, L.; Vrielink, A.; Sampson, N.S.
The binding and release of oxygen and hydrogen peroxide are directed by a hydrophobic tunnel in cholesterol oxidase
Biochemistry
47
5368-5377
2008
Streptomyces sp. (P12676)
Wang, L.; Wang, W.
Coenzyme precursor-assisted expression of a cholesterol oxidase from Brevibacterium sp. in Escherichia coli
Biotechnol. Lett.
29
761-766
2007
Brevibacterium sp. DGCDC-82 (Q2I2N2), Brevibacterium sp. DGCDC-82 CCTCC M201008 (Q2I2N2)
Park, M.S.; Kwon, B.; Shim, J.J.; Huh, C.S.; Ji, G.E.
Heterologous expression of cholesterol oxidase in Bifidobacterium longum under the control of 16S rRNA gene promoter of bifidobacteria
Biotechnol. Lett.
30
165-172
2008
Streptomyces coelicolor
Nesbitt, N.M.; Sampson, N.S.
Antifungal tradecraft by cholesterol oxidase
Chem. Biol.
14
238-241
2007
Streptomyces natalensis
Mendes, M.V.; Recio, E.; Anton, N.; Guerra, S.M.; Santos-Aberturas, J.; Martin, J.F.; Aparicio, J.F.
Cholesterol oxidases act as signaling proteins for the biosynthesis of the polyene macrolide pimaricin
Chem. Biol.
14
279-290
2007
Streptomyces natalensis
Oezer, B.C.; Oezyoeruek, H.; Celebi, S.S.; Yildiz, A.
Amperometric enzyme electrode for free cholesterol determination prepared with cholesterol oxidase immobilized in poly(vinylferrocenium) film
Enzyme Microb. Technol.
40
262-265
2007
Streptomyces sp.
-
Brzostek, A.; Dziadek, B.; Rumijowska-Galewicz, A.; Pawelczyk, J.; Dziadek, J.
Cholesterol oxidase is required for virulence of Mycobacterium tuberculosis
FEMS Microbiol. Lett.
275
106-112
2007
Mycobacterium tuberculosis
Piubelli, L.; Pedotti, M.; Molla, G.; Feindler-Boeckh, S.; Ghisla, S.; Pilone, M.S.; Pollegioni, L.
On the oxygen reactivity of flavoprotein oxidases: An oxygen access tunnel and gate in Brevibacterium sterolicum cholesterol oxidase
J. Biol. Chem.
283
24738-24747
2008
Brevibacterium sterolicum
Srisawasdi, P.; Chaichanajarernkul, U.; Teerakranjana, N.; Kroll, M.H.
Implementation of cellulomonas cholesterol oxidase for total serum cholesterol determination by the endpoint method
J. Clin. Lab. Anal.
22
50-58
2008
Cellulomonas sp.
Bhattacharyya, S.; Stankovich, M.T.; Truhlar, D.G.; Gao, J.
Combined quantum mechanical and molecular mechanical simulations of one- and two-electron reduction potentials of flavin cofactor in water, medium-chain acyl-CoA dehydrogenase, and cholesterol oxidase
J. Phys. Chem. A
111
5729-5742
2007
Streptomyces sp. (P12676)
Aparicio, J.F.; Martin, J.F.
Microbial cholesterol oxidases: bioconversion enzymes or signal proteins?
Mol. Biosyst.
4
804-809
2008
Arthrobacter sp., Streptomyces sp., Rhodococcus equi, Rhodococcus erythropolis, Rhodococcus rhodochrous, Schizophyllum commune, Brevibacterium sterolicum (P22637)
Lyubimov, A.Y.; Heard, K.; Tang, H.; Sampson, N.S.; Vrielink, A.
Distortion of flavin geometry is linked to ligand binding in cholesterol oxidase
Protein Sci.
16
2647-2656
2007
Streptomyces sp.
Caldinelli, L.; Iametti, S.; Barbiroli, A.; Fessas, D.; Bonomi, F.; Piubelli, L.; Molla, G.; Pollegioni, L.
Relevance of the flavin binding to the stability and folding of engineered cholesterol oxidase containing noncovalently bound FAD
Protein Sci.
17
409-419
2008
Brevibacterium sterolicum
Parra, A.; Casero, E.; Pariente, F.; Vazquez, L.; Lorenzo, E.
Cholesterol oxidase modified gold electrodes as bioanalytical devices
Sens. Actuators B Chem.
B124
30-37
2007
Streptomyces sp.
-
Vrielink, A.; Ghisla, S.
Cholesterol oxidase: biochemistry and structural features
FEBS J.
276
6826-6843
2009
Brevibacterium sterolicum, Streptomyces hygroscopicus
Pollegioni, L.; Piubelli, L.; Molla, G.
Cholesterol oxidase: biotechnological applications
FEBS J.
276
6857-6870
2009
Streptomyces violascens, Arthrobacter sp., Rhodococcus equi, Mycobacterium sp., Nocardia erythropolis, Nocardia rhodochrous, Pseudomonas spp., Schizophyllum commune, uncultured Gammaproteobacteria bacterium, Streptoverticillum cholesterolicum, Brevibacterium sterolicum (P22637), uncultured Gammaproteobacteria bacterium Y-134
Lyubimov, A.Y.; Chen, L.; Sampson, N.S.; Vrielink, A.
A hydrogen-bonding network is important for oxidation and isomerization in the reaction catalyzed by cholesterol oxidase
Acta Crystallogr. Sect. D
65
1222-1231
2009
Streptomyces sp. (P12676)
Saxena, U.; Goswami, P.
Silk mat as bio-matrix for the immobilization of cholesterol oxidase
Appl. Biochem. Biotechnol.
162
1122-1131
2010
Pseudomonas fluorescens
Doukyu, N.
Characteristics and biotechnological applications of microbial cholesterol oxidases
Appl. Microbiol. Biotechnol.
83
825-837
2009
Streptomyces violascens, Pimelobacter simplex, Arthrobacter sp., Arthrobacter sp. (Q56DL0), Burkholderia pseudomallei, Corynebacterium cholesterolicum, Nocardia rhodochrous, Nocardia sp., Pseudomonas sp., Pseudomonas aeruginosa, Schizophyllum commune, Streptomyces fradiae, uncultured Gammaproteobacteria bacterium, Streptoverticillium cholesterolieum, Rhodococcus equi (A0A3S5YA89), Streptomyces griseus (A7RA76), Rhodococcus erythropolis (A9QAE7), Corynebacterium urealyticum (B1VGH1), Chromobacterium sp. (B5MGF8), Streptomyces sp. (P12676), Streptomyces sp. (Q55020), Brevibacterium sterolicum (P22637), Mycobacterium tuberculosis (P9WMV9), Paraburkholderia xenovorans (Q13UN0), Burkholderia thailandensis (Q2T0X3), Mycobacterium leprae (Q59530), Nocardia farcinica (Q5YRJ2), Streptomyces avermitilis (Q93H76), Burkholderia cepacia (Q93RE1), Streptomyces natalensis (Q9EW96), Streptomyces coelicolor (Q9L0H6), Burkholderia cepacia ST-200 (Q93RE1), Rhodococcus equi 103S (A0A3S5YA89), Nocardia farcinica IFM 10152 (Q5YRJ2), Pseudomonas sp. COX629, Corynebacterium urealyticum DSM 7109 (B1VGH1), Mycobacterium tuberculosis H37Rv (P9WMV9), Arthrobacter sp. IM79, uncultured Gammaproteobacteria bacterium Y-134
Li, B.; Wang, W.; Wang, F.; Wei, D.
Cholesterol oxidase ChoL is a critical enzyme that catalyzes the conversion of diosgenin to 4-ene-3-keto steroids in Streptomyces virginiae IBL-14
Appl. Microbiol. Biotechnol.
85
1831-1838
2010
Streptomyces virginiae (A7LGL0), Streptomyces virginiae, Streptomyces virginiae IBL-14 (A7LGL0), Streptomyces virginiae IBL-14
Volonte, F.; Pollegioni, L.; Molla, G.; Frattini, L.; Marinelli, F.; Piubelli, L.
Production of recombinant cholesterol oxidase containing covalently bound FAD in Escherichia coli
BMC Biotechnol.
10
33
2010
Brevibacterium sterolicum
Sagermann, M.; Ohtaki, A.; Newton, K.; Doukyu, N.
Structural characterization of the organic solvent-stable cholesterol oxidase from Chromobacterium sp. DS-1
J. Struct. Biol.
170
32-40
2010
Chromobacterium sp. (B5MGF8), Chromobacterium sp.
Fernandez de Las Heras, L.; Mascaraque, V.; Garcia Fernandez, E.; Navarro-Llorens, J.M.; Perera, J.; Drzyzga, O.
ChoG is the main inducible extracellular cholesterol oxidase of Rhodococcus sp. strain CECT3014
Microbiol. Res.
166
403-418
2011
Rhodococcus sp. (C5II17), Rhodococcus sp., Rhodococcus sp. CECT 3014 (C5II17)
Ghasemian, A.; Yazdi, M.; Sepehrizadeh, Z.; Yazdi, Z.; Zarrini, G.
Overexpression, one-step purification, and characterization of a type II cholesterol oxidase from a local isolate Rhodococcus sp. PTCC 1633
World J. Microbiol. Biotechnol.
25
773-779
2009
Rhodococcus sp. (Q157H4), Rhodococcus sp. PTCC 1633 (Q157H4)
-
Xin, Y.; Yang, H.; Xia, X.; Zhang, L.; Zhang, Y.; Tong, Y.; Chen, Y.; Wang, W.
Expression and comparison of recombinant cholesterol oxidases (COD) in Escherichia coli with native cholesterol oxidase expressed in Brevibacterium sp
Afr. J. Biotechnol.
10
14968-14976
2011
Brevibacterium sp., Brevibacterium sp. M201008
-
Praveen, V.; Srivastava, A.; Tripathi, C.K.
Purification and characterization of the enzyme cholesterol oxidase from a new isolate of Streptomyces sp.
Appl. Biochem. Biotechnol.
165
1414-1426
2011
Streptomyces parvus, Streptomyces parvus 13647 J
Kojima, K.; Kobayashi, T.; Tsugawa, W.; Ferri, S.; Sode, K.
Mutational analysis of the oxygen-binding site of cholesterol oxidase and its impact on dye-mediated dehydrogenase activity
J. Mol. Catal. B
88
41-46
2013
Streptomyces sp.
-
Yao, K.; Wang, F.; Zhang, H.; Wei, D.
Identification and engineering of cholesterol oxidases involved in the initial step of sterols catabolism in Mycobacterium neoaurum
Metab. Eng.
15
75-87
2013
Mycolicibacterium neoaurum (H9NJ43), Mycolicibacterium neoaurum (H9NJ52), Mycolicibacterium neoaurum
Lin, Y.; Fu, J.; Song, X.
Purification and characterization of an extracellular cholesterol oxidase from a Bordetella species
Process Biochem.
45
1563-1569
2010
Bordetella sp., Bordetella sp. B4
-
Niwas, R.; Singh, V.; Singh, R.; Tripathi, D.; Tripathi, C.K.
Production, purification and characterization of cholesterol oxidase from a newly isolated Streptomyces sp.
World J. Microbiol. Biotechnol.
29
2077-2085
2013
Streptomyces sp., Streptomyces sp. R-6
Golden, E.; Karton, A.; Vrielink, A.
High-resolution structures of cholesterol oxidase in the reduced state provide insights into redox stabilization
Acta Crystallogr. Sect. D
70
3155-3166
2014
Streptomyces sp. SA-COO (P12676)
Kumari, L.; Kanwar, S.S.
Purification and characterization of an extracellular cholesterol oxidase of Bacillus subtilis isolated from Tiger excreta
Appl. Biochem. Biotechnol.
178
353-367
2016
Bacillus subtilis
Reiss, R.; Faccio, G.; Thoeny-Meyer, L.; Richter, M.
Cloning, expression and biochemical characterization of the cholesterol oxidase CgChoA from Chryseobacterium gleum
BMC Biotechnol.
14
46
2014
Chryseobacterium gleum (A0A3S4PHH6), Chryseobacterium gleum, Chryseobacterium gleum DSM 16776 (A0A3S4PHH6)
Yehia, H.M.; Hassanein, W.A.; Ibraheim, S.M.
Purification and characterisation of the extracellular cholesterol oxidase enzyme from Enterococcus hirae
BMC Microbiol.
15
178
2015
Enterococcus hirae, Enterococcus hirae Mil-31
Liu, J.; Xian, G.; Li, M.; Zhang, Y.; Yang, M.; Yu, Y.; Lv, H.; Xuan, S.; Lin, Y.; Gao, L.
Cholesterol oxidase from Bordetella species promotes irreversible cell apoptosis in lung adenocarcinoma by cholesterol oxidation
Cell Death Dis.
5
e1372
2014
Bordetella sp.
Kaur, S.; Kaur, H.; Prasad, B.; Prasher, M.
Production and optimization of cholesterol oxidase from Rhodococcus species
Int. J. Pharm. Pharm. Sci.
7
265-268
2015
Rhodococcus sp., Rhodococcus sp. COP 2
-
Niwas, R.; Singh, V.; Singh, R.; Pant, G.; Mitra, K.; Tripathi, C.K.
Cholesterol oxidase production from entrapped cells of Streptomyces sp.
J. Basic Microbiol.
54
1233-1239
2014
Streptomyces sp.
Doukyu, N.; Nihei, S.
Cholesterol oxidase with high catalytic activity from Pseudomonas aeruginosa Screening, molecular genetic analysis, expression and characterization
J. Biosci. Bioeng.
120
24-30
2015
Pseudomonas aeruginosa (X5IDD2), Pseudomonas aeruginosa, Pseudomonas aeruginosa PA157 (X5IDD2)
Shao, M.; Rao, Z.; Zhang, X.; Xu, M.; Yang, T.; Li, H.; Xu, Z.; Yang, S.
Bioconversion of cholesterol to 4-cholesten-3-one by recombinant Bacillus subtilis expressing choM gene encoding cholesterol oxidase from Mycobacterium neoaurum JC-12
J. Chem. Technol. Biotechnol.
90
1811-1820
2015
Mycolicibacterium neoaurum (H9NJ43), Mycolicibacterium neoaurum (H9NJ52), Mycolicibacterium neoaurum JC-12 (H9NJ43), Mycolicibacterium neoaurum JC-12 (H9NJ52)
-
Pathak, L.; Singh, V.; Niwas, R.; Osama, K.; Khan, S.; Haque, S.; Tripathi, C.K.; Mishra, B.N.
Artificial intelligence versus statistical modeling and optimization of cholesterol oxidase production by using Streptomyces sp.
PLoS ONE
10
e0137268
2015
Streptomyces sp. NCIM 5500
Klink, M.; Brzezinska, M.; Szulc, I.; Brzostek, A.; Kielbik, M.; Sulowska, Z.; Dziadek, J.
Cholesterol oxidase is indispensable in the pathogenesis of Mycobacterium tuberculosis
PLoS ONE
8
e73333
2013
Mycobacterium tuberculosis
Kasabe, P.J.; Mali, G.T.; Dandge, P.B.
Assessment of alkaline cholesterol oxidase purified from Rhodococcus sp. PKPD-CL for its halo tolerance, detergent and organic solvent stability
Protein Expr. Purif.
116
30-41
2015
Rhodococcus sp., Rhodococcus sp. PKPD-CL
Fazaeli, A.; Golestani, A.; Lakzaei, M.; Rasi Varaei, S.S.; Aminian, M.
Expression optimization of recombinant cholesterol oxidase in Escherichia coli and its purification and characterization
AMB Express
8
183
2018
Streptomyces sp. SA-COO (P12676)
Hejazi, M.S.; Tabar, K.K.; Azarbaijani, R.; Nobar, L.Z.
Cloning and sequencing of partial segment of cholesterol oxidase encoding gene from Streptomyces luridus
Ann. Microbiol.
57
259-263
2007
Streptomyces luridus (Q1HKZ6), Streptomyces luridus ATCC 19782 (Q1HKZ6)
-
Gadbery, J.E.; Sampson, N.S.
Use of an isotope-coded mass tag (ICMT) method to determine the orientation of cholesterol oxidase on model membranes
Biochemistry
57
5370-5378
2018
Streptomyces sp. SA-COO (P12676)
Wali, H.; Rehman, F.U.; Umar, A.; Ahmed, S.
Cholesterol degradation and production of extracellular cholesterol oxidase from Bacillus pumilus W1 and Serratia marcescens W8
BioMed Res. Int.
2019
1359528
2019
Bacillus pumilus, Serratia marcescens, Bacillus pumilus W1, Serratia marcescens W8
El-Naggar, N.E.; Deraz, S.F.; Soliman, H.M.; El-Deeb, N.M.; El-Shweihy, N.M.
Purification, characterization and amino acid content of cholesterol oxidase produced by Streptomyces aegyptia NEAE 102
BMC Microbiol.
17
76
2017
Streptomyces aegyptia, Streptomyces aegyptia NEAE 102
Szulc-Kielbik, I.; Brzostek, A.; Gatkowska, J.; Kielbik, M.; Klink, M.
Determination of in vitro and in vivo immune response to recombinant cholesterol oxidase from Mycobacterium tuberculosis
Immunol. Lett.
228
103-111
2020
Mycobacterium tuberculosis
Hao, M.; Fan, G.; Zhang, Y.; Xin, Y.; Zhang, L.
Preparation and characterization of copper-Brevibacterium cholesterol oxidase hybrid nanoflowers
Int. J. Biol. Macromol.
126
539-548
2019
Brevibacterium sp. DGCDC-82 (Q2I2N2)
Devi, S.; Sharma, B.; Kumar, R.; Singh Kanwar, S.
Purification, characterization, and biological cytotoxic activity of the extracellular cholesterol oxidase produced by Castellaniella sp. COX
J. Basic Microbiol.
60
253-267
2020
Castellaniella sp.
Chernov, K.G.; Neuvonen, M.; Brock, I.; Ikonen, E.; Verkhusha, V.V.
Introducing inducible fluorescent split cholesterol oxidase to mammalian cells
J. Biol. Chem.
292
8811-8822
2017
Chromobacterium sp. DS-1 (B5MGF8)
Szulc-Kielbik, I.; Kielbik, M.; Przygodzka, P.; Brzostek, A.; Dziadek, J.; Klink, M.
Mycobacterium tuberculosis requires cholesterol oxidase to disrupt TLR2 signalling in human macrophages
Mediators Inflamm.
2019
2373791
2019
Mycobacterium tuberculosis (P9WMV9), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (P9WMV9)
Fazaeli, A.; Golestani, A.; Lakzaei, M.; Rasi Varaei, S.S.; Aminian, M.
Expression optimization, purification, and functional characterization of cholesterol oxidase from Chromobacterium sp. DS1
PLoS ONE
14
e0212217
2019
Chromobacterium sp. DS1 (B5MGF8)
Doukyu, N.; Ishikawa, M.
Cholesterol oxidase from Rhodococcus erythropolis with high specificity toward beta-cholestanol and pytosterols
PLoS ONE
15
e0241126
2020
Rhodococcus erythropolis (C0ZNA9), Rhodococcus erythropolis (C0ZPW5), Rhodococcus erythropolis, Rhodococcus erythropolis PR4 (C0ZNA9), Rhodococcus erythropolis PR4 (C0ZPW5), Rhodococcus erythropolis PR4
Alapati, K.; Handanahal, S.
Characterization of cholesterol oxidase from a marine Streptomyces sp. and its cytotoxicity
Process Biochem.
89
175-185
2020
Streptomyces sp. AKHSS
-
Qin, H.M.; Wang, J.W.; Guo, Q.; Li, S.; Xu, P.; Zhu, Z.; Sun, D.; Lu, F.
Refolding of a novel cholesterol oxidase from Pimelobacter simplex reveals dehydrogenation activity
Protein Expr. Purif.
139
1-7
2017
Pimelobacter simplex (A0A0A1DJ35), Pimelobacter simplex
Harb, L.H.; Arooj, M.; Vrielink, A.; Mancera, R.L.
Computational site-directed mutagenesis studies of the role of the hydrophobic triad on substrate binding in cholesterol oxidase
Proteins
85
1645-1655
2017
Streptomyces sp. SA-COO (P12676)
Qin, H.M.; Zhu, Z.; Ma, Z.; Xu, P.; Guo, Q.; Li, S.; Wang, J.W.; Mao, S.; Liu, F.; Lu, F.
Rational design of cholesterol oxidase for efficient bioresolution of cholestane skeleton substrates
Sci. Rep.
7
16375
2017
Pimelobacter simplex
Yu, L.J.; Golden, E.; Chen, N.; Zhao, Y.; Vrielink, A.; Karton, A.
Computational insights for the hydride transfer and distinctive roles of key residues in cholesterol oxidase
Sci. Rep.
7
17265
2017
Streptomyces sp. SA-COO (P12676)
Srivastava, A.; Singh, V.; Haque, S.; Pandey, S.; Mishra, M.; Jawed, A.; Shukla, P.K.; Singh, P.K.; Tripathi, C.K.M.
Response surface methodology-genetic algorithm based medium optimization, purification, and characterization of cholesterol oxidase from Streptomyces rimosus
Sci. Rep.
8
10913
2018
Streptomyces rimosus, Streptomyces rimosus MTCC 10792
Parra, A.; Casero, E.; Pariente, F.; Vazquez, L.; Lorenzo, E.
Cholesterol oxidase modified gold electrodes as bioanalytical devices
Sens. Actuators B Chem.
B124
30-37
2007
Streptomyces sp.
-
html completed
