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Information on EC 1.1.1.42 - isocitrate dehydrogenase (NADP+) and Organism(s) Pseudomonas aeruginosa

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IUBMB Comments
Requires Mn2+ or Mg2+ for activity. Unlike EC 1.1.1.41, isocitrate dehydrogenase (NAD+), oxalosuccinate can be used as a substrate. In eukaryotes, isocitrate dehydrogenase exists in two forms: an NAD+-linked enzyme found only in mitochondria and displaying allosteric properties, and a non-allosteric, NADP+-linked enzyme that is found in both mitochondria and cytoplasm . The enzyme from some species can also use NAD+ but much more slowly [6,7].
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This record set is specific for:
Pseudomonas aeruginosa
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Word Map
The taxonomic range for the selected organisms is: Pseudomonas aeruginosa
The enzyme appears in selected viruses and cellular organisms
Reaction Schemes
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Synonyms
isocitrate dehydrogenase 1, nadp-isocitrate dehydrogenase, nadp-dependent isocitrate dehydrogenase, isocitrate dehydrogenase-1, nadp-icdh, nadp-idh, nadp+-dependent isocitrate dehydrogenase, nadp-linked isocitrate dehydrogenase, nadp-specific isocitrate dehydrogenase, nadp+-specific isocitrate dehydrogenase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
CtIDP1
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CtIDP2
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IDH
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IDP
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isocitrate dehydrogenase (NADP)
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isocitrate dehydrogenase (NADP-dependent)
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isocitrate dehydrogenase (nicotinamide adenine dinucleotide phosphate)
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NADP isocitric dehydrogenase
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NADP+-linked isocitrate dehydrogenase
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NADP+-specific ICDH
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NADP-dependent isocitrate dehydrogenase
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NADP-dependent isocitric dehydrogenase
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NADP-linked isocitrate dehydrogenase
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NADP-specific isocitrate dehydrogenase
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oxalosuccinate decarboxylase
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oxalsuccinic decarboxylase
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PS-NADP-IDH
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
oxidative decarboxylation
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redox reaction
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reductive carboxylation
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SYSTEMATIC NAME
IUBMB Comments
isocitrate:NADP+ oxidoreductase (decarboxylating)
Requires Mn2+ or Mg2+ for activity. Unlike EC 1.1.1.41, isocitrate dehydrogenase (NAD+), oxalosuccinate can be used as a substrate. In eukaryotes, isocitrate dehydrogenase exists in two forms: an NAD+-linked enzyme found only in mitochondria and displaying allosteric properties, and a non-allosteric, NADP+-linked enzyme that is found in both mitochondria and cytoplasm [6]. The enzyme from some species can also use NAD+ but much more slowly [6,7].
CAS REGISTRY NUMBER
COMMENTARY hide
9028-48-2
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UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
A0A8G6GSW9_PSEAI
741
0
81682
TrEMBL
-
A0A8H0X771_PSEAI
741
0
81691
TrEMBL
-
A0A8G3VKS9_PSEAI
741
0
81634
TrEMBL
-
A0A8G4N4P4_PSEAI
741
0
81569
TrEMBL
-
A0A077JVI5_PSEAI
741
0
81622
TrEMBL
-
A0A5E5R9K3_PSEAI
741
0
81637
TrEMBL
-
A0A659BG16_PSEAI
741
0
81637
TrEMBL
-
A0A643EK55_PSEAI
741
0
81623
TrEMBL
-
A0A8G6W5T5_PSEAI
741
0
81674
TrEMBL
-
A0A8G5NVH5_PSEAI
741
0
81635
TrEMBL
-
A0A8G6YUV6_PSEAI
418
0
45489
TrEMBL
-
A0A8G3ZFX3_PSEAI
741
0
81652
TrEMBL
-
A0A2R3ILD3_PSEAI
418
0
45605
TrEMBL
-
A0A8G6W3H9_PSEAI
418
0
45558
TrEMBL
-
A0A643IS82_PSEAI
741
0
81596
TrEMBL
-
A0A8G4P6I4_PSEAI
741
0
81578
TrEMBL
-
A0A8G5FVK9_PSEAI
741
0
81635
TrEMBL
-
A0A7M3AST6_PSEAI
741
0
81638
TrEMBL
-
A0A8G7SJ43_PSEAI
741
0
81650
TrEMBL
-
A0A8G2RBC8_PSEAI
741
0
81632
TrEMBL
-
A0A8G3YLR1_PSEAI
418
0
45605
TrEMBL
-
A0A8G7EZ06_PSEAI
741
0
81650
TrEMBL
-
A0A8G3A4P7_PSEAI
741
0
81618
TrEMBL
-
A0A0F7QRI5_PSEAI
741
0
81622
TrEMBL
-
A0A8G3Y6L6_PSEAI
741
0
81664
TrEMBL
-
A0A8G2NG99_PSEAI
741
0
81592
TrEMBL
-
A0A8G4LJA7_PSEAI
418
0
45505
TrEMBL
-
A0A8G6Z3J7_PSEAI
741
0
81595
TrEMBL
-
A0A8G6V6Q2_PSEAI
741
0
81666
TrEMBL
-
A0A0A8RTF8_PSEAI
741
0
81820
TrEMBL
-
A0A8B4ZDE3_PSEAI
741
0
81623
TrEMBL
-
A0A8G4DYS8_PSEAI
741
0
81607
TrEMBL
-
A0A8G1JNE2_PSEAI
743
0
81900
TrEMBL
-
A0A4P0UF34_PSEAI
495
0
54765
TrEMBL
-
A0A8G3JD92_PSEAI
741
0
81594
TrEMBL
-
A0A3M5DBF8_PSEAI
741
0
81650
TrEMBL
-
A0A8G7DK78_PSEAI
741
0
81652
TrEMBL
-
A0A8G6C4Q5_PSEAI
418
0
45618
TrEMBL
-
A0A485F2Y0_PSEAI
451
0
49672
TrEMBL
-
A0A8G5Z7H5_PSEAI
417
0
45506
TrEMBL
-
A0A6A9JKV1_PSEAI
741
0
81664
TrEMBL
-
A0A367MCY4_PSEAI
615
0
68049
TrEMBL
-
A0A8G7KSA5_PSEAI
741
0
81710
TrEMBL
-
A0A0C7CY91_PSEAI
741
0
81636
TrEMBL
-
A0A8G3YMW5_PSEAI
741
0
81577
TrEMBL
-
A0A8F9J1W8_PSEAI
418
0
45607
TrEMBL
-
A0A8G8ERS1_PSEAI
418
0
45618
TrEMBL
-
A0A2R3IUM0_PSEAI
741
0
81664
TrEMBL
-
A0A8B5A404_PSEAI
741
0
81608
TrEMBL
-
A0A8G6KZC4_PSEAI
741
0
81610
TrEMBL
-
A0A8G7SJB9_PSEAI
418
0
45547
TrEMBL
-
A0A8G3QBB3_PSEAI
741
0
81656
TrEMBL
-
A0A8G5T8I1_PSEAI
741
0
81670
TrEMBL
-
A0A8G7TG62_PSEAI
741
0
81636
TrEMBL
-
A0A8G4P0R6_PSEAI
418
0
45549
TrEMBL
-
A0A367M880_PSEAI
132
0
13911
TrEMBL
-
A0A367M2C3_PSEAI
294
0
32653
TrEMBL
-
A0A069QAS5_PSEAI
418
0
45577
TrEMBL
-
A0A8G5QER8_PSEAI
418
0
45607
TrEMBL
-