Information on EC 1.1.1.37 - malate dehydrogenase

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The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea

EC NUMBER
COMMENTARY
1.1.1.37
-
RECOMMENDED NAME
GeneOntology No.
malate dehydrogenase
-
REACTION
REACTION DIAGRAM
COMMENTARY
ORGANISM
UNIPROT
LITERATURE
(S)-malate + NAD+ = oxaloacetate + NADH + H+
show the reaction diagram
also oxidizes some other 2-hydroxydicarboxylic acids
-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
oxidation
-
-
-
-
reduction
-
-
-
-
PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
anaerobic energy metabolism (invertebrates, cytosol)
-
-
C4 photosynthetic carbon assimilation cycle, NAD-ME type
-
-
formaldehyde assimilation I (serine pathway)
-
-
gluconeogenesis I
-
-
gluconeogenesis III
-
-
glyoxylate cycle
-
-
incomplete reductive TCA cycle
-
-
L-aspartate degradation II
-
-
methylaspartate cycle
-
-
mixed acid fermentation
-
-
pyruvate fermentation to propanoate I
-
-
reductive TCA cycle I
-
-
reductive TCA cycle II
-
-
superpathway of glyoxylate cycle and fatty acid degradation
-
-
TCA cycle I (prokaryotic)
-
-
TCA cycle II (plants and fungi)
-
-
TCA cycle III (animals)
-
-
TCA cycle IV (2-oxoglutarate decarboxylase)
-
-
TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)
-
-
TCA cycle VI (obligate autotrophs)
-
-
aspartate and asparagine metabolism
-
-
C4 and CAM-carbon fixation
-
-
citric acid cycle
-
-
Citrate cycle (TCA cycle)
-
-
Cysteine and methionine metabolism
-
-
Pyruvate metabolism
-
-
Glyoxylate and dicarboxylate metabolism
-
-
Methane metabolism
-
-
Carbon fixation in photosynthetic organisms
-
-
Carbon fixation pathways in prokaryotes
-
-
Metabolic pathways
-
-
Biosynthesis of secondary metabolites
-
-
Microbial metabolism in diverse environments
-
-
Biosynthesis of antibiotics
-
-
SYSTEMATIC NAME
IUBMB Comments
(S)-malate:NAD+ oxidoreductase
Also oxidizes some other 2-hydroxydicarboxylic acids.
SYNONYMS
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
(R)-2-hydroxyacid dehydrogenase
-
-
-
-
(S)-malate dehydrogenase
-
-
cMDH
-
-
cMDH
-
cytosolic isoenzyme
cytosolic malate dehydrogenase
-
cytosolic malate dehydrogenase
-
-
cytosolic malate dehydrogenase
-
cytosolic MDH
-
-
cytosolic NAD-dependent malate dehydrogenase
-
halophilic malate dehydrogenase
-
L-malate dehydrogenase
-
-
-
-
L-malate dehydrogenase
-
-
L-malate-NAD oxidoreductase
-
-
L-malate: NAD oxidoreductase
-
-
L-malate:NAD-oxidoreductase
-
m-MDH
-
-
malate (NAD) dehydrogenase
-
-
-
-
malate dehydrogenase
-
-
malate dehydrogenase
-
malate dehydrogenase
Pontonia pinnophylax
-
-
malate dehydrogenase
-
-
malate dehydrogenase
-
malate dehydrogenase
-
-
malate dehydrogenase (NAD)
-
-
-
-
malate dehydrogenase 1
-
-
malate dehydrogenase 2
-
malate: NAD oxidoreductase
-
-
MalDH
Haloarcula marismortui DSM 3752
-
-
malic acid dehydrogenase
-
-
-
-
malic dehydrogenase
-
-
-
-
mbNAD-MDH
-
-
-
-
MDH
Beggiatoa leptomitiformis D-402
-
-
-
MDH
Mucor circinelloides f. lusitanicus INMI
-
-
-
MDH
Pontonia pinnophylax
-
-
MDH
Rhodobacter sphaeroides 2R
-
-
-
MDH
Streptomyces avermitilis MA-4680
-
-
-
MDH
-
-
MDH A
-
isoform
MDH B1
-
isoform
MDH B2
-
isoform
mitochondrial malate dehydrogenase
-
mitochondrial malate dehydrogenase
-
mitochondrial malate dehydrogenase
-
-
mitochondrial malate dehydrogenase
-
-
mMDH
-
-
mMDH
mitochondrial isoenzyme
mMDH
-
-
mMDH
-
mitochondrial isoenzyme
NAD+-dependent malate dehydrogenase
-
-
NAD+-dependent MDH
-
-
NAD+-MDH enzymes
-
-
NAD-dependent malate dehydrogenase
-
-
-
-
NAD-dependent malic dehydrogenase
-
-
-
-
NAD-L-malate dehydrogenase
-
-
-
-
NAD-linked malate dehydrogenase
-
-
-
-
NAD-malate dehydrogenase
-
-
-
-
NAD-malic dehydrogenase
-
-
-
-
NAD-specific malate dehydrogenase
-
-
-
-
peroxisomal NAD+-malate dehydrogenase 1
-
-
peroxisomal NAD+-malate dehydrogenase 2
-
-
regulatory subunit of nucleic acid-conducting channel
-
-
VEG69
-
-
-
-
Vegetative protein 69
-
-
-
-
[LDH-like] MDH
-
-
mNAD-MDH
-
-
-
-
additional information
-
MDH belongs to the superfamily of 2-ketoacid NAD(P)+-dependent dehydrogenases
CAS REGISTRY NUMBER
COMMENTARY
9001-64-3
-
ORGANISM
COMMENTARY
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
-
Uniprot
Manually annotated by BRENDA team
pineapple, cv. Havaiano
-
-
Manually annotated by BRENDA team
mMDH1; isozymes mMDH1 and mMDH2, eight genes encoding isoforms of NAD-dependent MDH
UniProt
Manually annotated by BRENDA team
mMDH2; isozymes mMDH1 and mMDH2, eight genes encoding isoforms of NAD-dependent MDH
UniProt
Manually annotated by BRENDA team
the Arabidopsis genome encodes eight putative NAD+-MDH enzymes
-
-
Manually annotated by BRENDA team
strain B60
-
-
Manually annotated by BRENDA team
Aspergillus niger B60
strain B60
-
-
Manually annotated by BRENDA team
moderate thermophile, designated BI
-
-
Manually annotated by BRENDA team
Beggiatoa leptomitiformis D-402
strain D-402
-
-
Manually annotated by BRENDA team
bovine
-
-
Manually annotated by BRENDA team
3I1B-143 bacteroids
-
-
Manually annotated by BRENDA team
two isozymes
-
-
Manually annotated by BRENDA team
Bryophyllum calycinum
-
-
-
Manually annotated by BRENDA team
Citrus sp.
lemon fruit
-
-
Manually annotated by BRENDA team
Coccochloris peniocystis
no. 1548
-
-
Manually annotated by BRENDA team
Coccochloris peniocystis 1548
no. 1548
-
-
Manually annotated by BRENDA team
Stanier strain 78, ATCC 11996
-
-
Manually annotated by BRENDA team
strain NC4 (ATCC 24697)
-
-
Manually annotated by BRENDA team
Dictyostelium discoideum NC4
strain NC4 (ATCC 24697)
-
-
Manually annotated by BRENDA team
Drosophila melanogaster Oregon K
Oregon K
-
-
Manually annotated by BRENDA team
Texmelucan
-
-
Manually annotated by BRENDA team
Drosophila virilis Texmelucan
Texmelucan
-
-
Manually annotated by BRENDA team
horse
-
-
Manually annotated by BRENDA team
gene mdh
UniProt
Manually annotated by BRENDA team
strain K-12
UniProt
Manually annotated by BRENDA team
strain MG1655, gene mdh
UniProt
Manually annotated by BRENDA team
Escherichia coli MG1655
strain MG1655, gene mdh
UniProt
Manually annotated by BRENDA team
Euglena gracilis SM-ZK
SM-ZK
-
-
Manually annotated by BRENDA team
brown shrimp
-
-
Manually annotated by BRENDA team
Flavobacterium frigidimaris KUC-1
strain KUC-1
-
-
Manually annotated by BRENDA team
Flavobacterium frigidimaris KUC-1
strain KUC-1
Uniprot
Manually annotated by BRENDA team
Duch. cv. Elsanta
-
-
Manually annotated by BRENDA team
N.C.A 1503, N.C.A. 1518 Ra2, 2184
-
-
Manually annotated by BRENDA team
soybean, Williams 79 cultivar
-
-
Manually annotated by BRENDA team
Haloarcula marismortui DSM 3752
-
UniProt
Manually annotated by BRENDA team
Halobacterium salinarum NRC 36014
-
-
-
Manually annotated by BRENDA team
isoforms A1, A2 and B
-
-
Manually annotated by BRENDA team
marine snail
-
-
Manually annotated by BRENDA team
N.C.I.B. 10486
-
-
Manually annotated by BRENDA team
Laceyella sacchari NCIB 10486
N.C.I.B. 10486
-
-
Manually annotated by BRENDA team
strain D-405
-
-
Manually annotated by BRENDA team
Macromonas bipunctata D-405
strain D-405
-
-
Manually annotated by BRENDA team
; gene MdcyMDH
UniProt
Manually annotated by BRENDA team
Orin apple
UniProt
Manually annotated by BRENDA team
type strain JF1, strain GP1
-
-
Manually annotated by BRENDA team
Methanospirillum hungatei GPI
strain GPI
-
-
Manually annotated by BRENDA team
Methanothermobacter thermautotrophicum
-
-
-
Manually annotated by BRENDA team
strain 2D2
SwissProt
Manually annotated by BRENDA team
strain 5710
-
-
Manually annotated by BRENDA team
strain 2D2
SwissProt
Manually annotated by BRENDA team
strain 5710
-
-
Manually annotated by BRENDA team
Mucor circinelloides f. lusitanicus INMI
strain INMI
-
-
Manually annotated by BRENDA team
H37Rv, H37Ra, BCG
-
-
Manually annotated by BRENDA team
marine diatom
-
-
Manually annotated by BRENDA team
no activity in Chromatium sp.
-
-
-
Manually annotated by BRENDA team
no activity in Mycobacterium fortuitum
-
-
-
Manually annotated by BRENDA team
no activity in Mycobacterium smegmatis
-
-
-
Manually annotated by BRENDA team
no activity in Mycobacterium smegmatis 607
-
-
-
Manually annotated by BRENDA team
lamb
-
-
Manually annotated by BRENDA team
wild-type strain NRRL 1555 (-)
-
-
Manually annotated by BRENDA team
Pontonia pinnophylax
inhabiting the mantle cavity of host Pinna nobilis
-
-
Manually annotated by BRENDA team
; a hyperthermophilic archaeon, strain DSM 4184
-
-
Manually annotated by BRENDA team
m-MDH chromosomal DNA sequence
SwissProt
Manually annotated by BRENDA team
mitochondrial malate dehydrogenase cDNA sequence
SwissProt
Manually annotated by BRENDA team
rat; Sprague-Dawley
-
-
Manually annotated by BRENDA team
Rattus norvegicus Sprague-Dawley
Sprague-Dawley
-
-
Manually annotated by BRENDA team
B100; formerly Rhodopseudomonas capsulata
-
-
Manually annotated by BRENDA team
B100; formerly Rhodopseudomonas capsulata; strain 37b4
-
-
Manually annotated by BRENDA team
strain 37b, strain number DSM 938
-
-
Manually annotated by BRENDA team
Rhodobacter capsulatus 37b4
strain 37b4
-
-
Manually annotated by BRENDA team
Rhodobacter capsulatus B100
B100
-
-
Manually annotated by BRENDA team
Rhodobacter sphaeroides 2R
strain 2R
-
-
Manually annotated by BRENDA team
Rhodocyclus purpureus 6770
strain 6770
-
-
Manually annotated by BRENDA team
Rhodomicrobium vannielii EY33
strain EY33
-
-
Manually annotated by BRENDA team
Rhodopseudomonas palustris f8pt
strain f8pt
-
-
Manually annotated by BRENDA team
Rhodospirillum rubrum 1.1.1
strain 1.1.1
-
-
Manually annotated by BRENDA team
castor bean
-
-
Manually annotated by BRENDA team
Mdh2; isozyme Mdh2
UniProt
Manually annotated by BRENDA team
This UniProt-ID has been deleted; isozyme Mdh1
-
-
Manually annotated by BRENDA team
DSM 13855
-
-
Manually annotated by BRENDA team
salmon
-
-
Manually annotated by BRENDA team
salmonid fish
-
-
Manually annotated by BRENDA team
isoenzyme cMDH-L; Pelican barracuda
SwissProt
Manually annotated by BRENDA team
isoenzyme cMDH-S; Pelican barracuda
SwissProt
Manually annotated by BRENDA team
isoenzyme mMDH; Pelican barracuda
SwissProt
Manually annotated by BRENDA team
Streptomyces avermitilis MA-4680
-
-
-
Manually annotated by BRENDA team
strain 6803 CF
-
-
Manually annotated by BRENDA team
Synechocystis sp. 6803 CF
strain 6803 CF
-
-
Manually annotated by BRENDA team
N.C.I.B. 11185
-
-
Manually annotated by BRENDA team
Thermobifida fusca NCIB 11185
N.C.I.B. 11185
-
-
Manually annotated by BRENDA team
strain B
-
-
Manually annotated by BRENDA team
strain YT-1
-
-
Manually annotated by BRENDA team
Thermus aquaticus B
strain B
-
-
Manually annotated by BRENDA team
Thermus aquaticus YT-1
strain YT-1
-
-
Manually annotated by BRENDA team
wild-type enzyme and mutant EX7 (with altered coenzyme specificity from NADH towards NADPH)
Uniprot
Manually annotated by BRENDA team
Thermus thermophilus AT-62
AT-62
-
-
Manually annotated by BRENDA team
strain TV 10-02, strain Tv-1961, strain Tv-1973
-
-
Manually annotated by BRENDA team
L. cv. H4564
UniProt
Manually annotated by BRENDA team
black gram, mung bean
-
-
Manually annotated by BRENDA team
Viola sp.
-
-
-
Manually annotated by BRENDA team
gene YlMDH2; several strains, overview, gene YALI0E14190g or YlMDH2
UniProt
Manually annotated by BRENDA team
isozyme YlMDH1; gene YALI0D16753g or YlMDH1
UniProt
Manually annotated by BRENDA team
corn
-
-
Manually annotated by BRENDA team
Zea mays Goldener Badischer Landmais
-
-
-
Manually annotated by BRENDA team
Zea mays VA35
-
-
-
Manually annotated by BRENDA team
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
evolution
the three different enzyme forms in cytosol, peroxisome and mitochondrion are encoded by three different genes in Saccharomyces cerevisiae, but by only two genes in Yarrowia lipolytica, where the second gene is differentiated into cytosolic and peroxisomal isozymes by alternative splicing, overview
evolution
-
the plasma membrane-associated isozyme belongs belongs to the lactate dehydrogenase/MDH superfamily, MDH type 2 family
evolution
Zea mays Goldener Badischer Landmais
-
the plasma membrane-associated isozyme belongs belongs to the lactate dehydrogenase/MDH superfamily, MDH type 2 family
-
malfunction
absence of either the peroxisomal or the cytosolic form of the MDH does not affect growth rate, irrespective of the carbon source
malfunction
-
exposure of maize plants to excess concentrations of Zn2+ and Cu2+ in the hydroponic solution inhibited lateral root growth, decreased malate dehydrogenase activity and changed isoform profiles
malfunction
-
knockdown of MDH1 in young human dermal fibroblasts and the IMR90 human fibroblast cell line results in the appearance of significant cellular senescence features, including senescence-associated beta-galactosidase staining, flattened and enlarged morphology, increased population doubling time, and elevated p16INK4A and p21CIP1 protein levels. The NAD/NADH ratio is decreased by 90% in MDH1 knockdown dermal fibroblasts but only by about 30% in MDH2 knockdown dermal fibroblasts
physiological function
mitochondrial and cytosolic MDH isozymes are required for maintaining the balance of NAD+ and NADH in mitochondria and cytosol
physiological function
-
MDH is an essential enzyme in the tricarboxylic acid cycle. Inhibition of mMDH activity affects cell energy production, probably leading to the inhibition of proliferation. Inhibition of mMDH activity by DIF-1 and 2-MIDIF-1 can be one of the mechanisms to induce anti-proliferative effects, independent of the inhibition of the Wnt/beta-catenin signaling pathway
physiological function
cyMDH is an enzyme crucial for malate synthesis in the cytosol. Involvement of MdcyMDH directly in malate synthesis and indirectly in malate accumulation through the regulation of genes/enzymes associated with malate degradation and transportation, gluconeogenesis and the tricarboxylic acid cycle.; cytosolic NAD-dependent malate dehydrogenase is an enzyme crucial for malate synthesis in the cytosol
physiological function
cyMDH is an enzyme crucial for malic acid synthesis in the cytosol. Role of the apple cyMDH gene in growth and tolerance to cold and salt stresses. cyMDH was sensitive to cold and salt stresses. cyMDH overexpression favourably contributes to cell and plant growth and confers stress tolerance in the apple
physiological function
mMDH has a role in maximizing photorespiratory rate. The slow-growing mmdh1mmdh2 mutant has elevated leaf respiration rate in the dark and light, without loss of photosynthetic capacity, suggesting that mMDH normally uses NADH to reduce oxaloacetate to malate, which is then exported to the cytosol, rather than to drive mitochondrial respiration. Increased respiratory rate in leaves can account in part for the low net CO2 assimilation and slow growth rate of mmdh1mmdh2. Loss of mMDH also affects photorespiration with alterations in CO2 assimilation/intercellular CO2 at low CO2, and the light-dependent elevated concentration of photorespiratory metabolites; mMDH has a role in maximizing the photorespiratory rate. The slow-growing mmdh1mmdh2 mutant has elevated leaf respiration rate in the dark and light, without loss of photosynthetic capacity, suggesting that mMDH normally uses NADH to reduce oxaloacetate to malate, which is then exported to the cytosol, rather than to drive mitochondrial respiration. Increased respiratory rate in leaves can account in part for the low net CO2 assimilation and slow growth rate of mmdh1mmdh2. Loss of mMDH also affects photorespiration with alterations in CO2 assimilation/intercellular CO2 at low CO2, and the light-dependent elevated concentration of photorespiratory metabolites
physiological function
-
besides its function in malate synthesis, MDH is responsible for the exchange of reducing equivalents between metabolic pathways in distinct cell compartments
physiological function
-
MDH1 plays a critical role in the cellular senescence of human fibroblasts. MDH1 is the major regulator of the cofactor NAD, the loss of which induces cellular senescence
physiological function
Zea mays Goldener Badischer Landmais
-
besides its function in malate synthesis, MDH is responsible for the exchange of reducing equivalents between metabolic pathways in distinct cell compartments
-
malfunction
Zea mays VA35
-
exposure of maize plants to excess concentrations of Zn2+ and Cu2+ in the hydroponic solution inhibited lateral root growth, decreased malate dehydrogenase activity and changed isoform profiles
-
additional information
-
mMDH inhibition is of minor relevance for the growth inhibition caused by paullones
additional information
inverse correlation between mMDH and ascorbate content; inverse correlation between mMDH and ascorbate content
additional information
possible role for alternative splicing in the regulation of MDH compartmentalization in this yeast, gene YlMDH2 encodes the cytosolic and peroxisomal forms of MDH
additional information
-
a significant decrease of both mass and elongation of maize roots and shoots, as well as loss of root turgor and completely repressed lateral root growth were demonstrated in 0.1 mM Cu2+ and 5 mM Zn2+ treatments, overview
additional information
Zea mays VA35
-
a significant decrease of both mass and elongation of maize roots and shoots, as well as loss of root turgor and completely repressed lateral root growth were demonstrated in 0.1 mM Cu2+ and 5 mM Zn2+ treatments, overview
-
SUBSTRATE
PRODUCT                      
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
LITERATURE
(Substrate)
COMMENTARY
(Product)
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(2S,3S)-tartrate + NAD+
? + NADH
show the reaction diagram
-
-
-
r
(2S,3S)-tartrate + NAD+
? + NADH
show the reaction diagram
-
-
-
r
(S)-2-hydroxyglutarate + NAD+
2-oxoglutarate + NADH + H+
show the reaction diagram
-
oxidized at an extremely slow rate, less than 0.001% of the rate of L-malate oxidation
-
r
(S)-malate + 3-acetylpyridine-adenine dinucleotide
oxaloacetate + reduced 3-acetylpyridine-adenine dinucleotide + H+
show the reaction diagram
-
can also use 3-acetylpyridine-adenine as cofactor
-
r
(S)-malate + acetylpyridine adenine dinucleotide
oxaloacetate + reduced acetylpyridine adenine dinucleotide
show the reaction diagram
-
-
?
(S)-malate + NAD(P)+
oxaloacetate + NAD(P)H
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
?
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
?
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
?
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
?
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
Methanothermobacter thermautotrophicum
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
Methanothermobacter thermautotrophicum
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
?
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
Citrus sp.
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
Coccochloris peniocystis
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
?
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
Bryophyllum calycinum
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
?
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
?
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
Pontonia pinnophylax
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
?
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
?
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
?
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
?
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
?
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
?
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
?
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
?
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
?
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
mitochondrial enzyme form mMDH functions in citric acid cycle and in the malate-aspartate shuttle
-
?
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
mitochondrial enzyme, Krebs cycle
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
NAD+ binds first to the enzyme and then oxaloacetate is consequently released randomly via an ordered via an ordered bi-bi mechanism
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
low activity in this direction
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
malate dehydrogenase is an oligomeric enzyme that catalyzes the reversible oxidation of malate to oxaloacetate in the presence of NAD+, MDH is an essential metabolic enzyme in the citric acid cycle
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
the NAD-dependent mitochondrial malate dehydrogenase plays pivotal roles in tricarboxylic acid and is crucial for the survival and pathogenecity of parasites
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
the peroxisomal malate dehydrogenase functions in beta-oxidation, serving to reoxidize NADH, but not in the glyoxylate cycle
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
Pontonia pinnophylax
-
enzyme activity and electrophoretic pattern of MDH and lactate dehydrogenase, EC 1.1.1.27, compared in relation to heat and urea inactivation, overview
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
mitochondrial isozyme Mdh1 preferably catalyzes the oxaloacetate formation, overview
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
residues I12, R81, M85, G210, and V214 determine the enzyme's substrate specificity
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
the cytoplasmic isozyme Mdh2 catalyzes preferably the malate formation, overview
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
highly specific for oxaloacetate and malate
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
the envelope- and plasma membrane-bound NAD-MDH exhibit the highest affinities for OAA, leaf plasma membrane-bound MDH exhibits a high capacity for both reaction directions (malate oxidation and oxaloacetate reduction), while the two chloroplast isoforms (stromal and envelope-bound) preferentially reduce oxaloacetate
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
the reverse reaction is highly preferred, with a 1050fold higher kcat/Km value
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
1246fold preference for oxaloacetate reduction over L-malate oxidation
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
the reduction of oxaloacetate with NADH is preferred. Malate is oxidized by NAD+ at 10% of the maximal velocity for the reduction of oxaloacetate with NADH. No oxidation of malate with NADP+ as coenzyme
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
Rhodobacter capsulatus B100
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
Rhodobacter capsulatus B100
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
Drosophila melanogaster Oregon K
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
Streptomyces avermitilis MA-4680
-
1246fold preference for oxaloacetate reduction over L-malate oxidation
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
Rattus norvegicus Sprague-Dawley
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
Rattus norvegicus Sprague-Dawley
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
Mucor circinelloides f. lusitanicus INMI
-
-
-
?
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
Rhodomicrobium vannielii EY33
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
Rhodomicrobium vannielii EY33
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
Beggiatoa leptomitiformis D-402
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
Thermus aquaticus YT-1
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
Aspergillus niger B60
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
Drosophila virilis Texmelucan
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
Synechocystis sp. 6803 CF
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
Zea mays Goldener Badischer Landmais
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
Dictyostelium discoideum NC4
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
Rhodospirillum rubrum 1.1.1
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
Rhodospirillum rubrum 1.1.1
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
Thermus thermophilus AT-62
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
Rhodobacter capsulatus 37b4
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
Flavobacterium frigidimaris KUC-1
-
NAD+ binds first to the enzyme and then oxaloacetate is consequently released randomly via an ordered via an ordered bi-bi mechanism
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
Rhodocyclus purpureus 6770
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
Rhodocyclus purpureus 6770
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
Thermobifida fusca NCIB 11185
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
Coccochloris peniocystis 1548
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
Thermus aquaticus B
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
Laceyella sacchari NCIB 10486
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
Zea mays VA35
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
Euglena gracilis SM-ZK
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
Rhodobacter sphaeroides 2R
-
-
-
?
(S)-malate + NAD+
acetate + CO2 + H2 + NADH
show the reaction diagram
-
-
-
?
(S)-malate + NADP+
oxaloacetate + NADPH + H+
show the reaction diagram
-
-
r
(S)-malate + NADP+
oxaloacetate + NADPH + H+
show the reaction diagram
Flavobacterium frigidimaris, Flavobacterium frigidimaris KUC-1
-
-
-
ir
1,4,5,6-tetrahydronicotinamide + L-malate
?
show the reaction diagram
-
-
-
-
?
2-oxobutyrate + NADH
2-hydroxybutyrate + NAD+
show the reaction diagram
-
-
-
?
3-acetylpyridine adenine dinucleotide + L-malate
?
show the reaction diagram
-
-
-
-
?
3-bromopyruvate + NADH
3-bromo-2-hydroxypropanoate + NAD+
show the reaction diagram
about 10% of the activity with oxaloacetate at pH 6.8
-
?
alpha-keto-malonate + NADH
? + NAD+
show the reaction diagram
-
-
-
-
alpha-keto-malonate + NADH
? + NAD+
show the reaction diagram
-
-
-
?
alpha-keto-malonate + NADH
? + NAD+
show the reaction diagram
-
-
-
?
alpha-keto-malonate + NADH
? + NAD+
show the reaction diagram
-
-
-
ir
alpha-keto-malonate + NADH
? + NAD+
show the reaction diagram
-
reduced by m-MDH with half of the turnover number observed with oxaloacetate
-
?
alpha-ketoglutarate + NADH
2-hydroxyglutarate + NAD+
show the reaction diagram
about 10% of the activity with oxaloacetate at pH 6.8 and at pH 8.2
-
?
alpha-ketoisovalerate + NADH
2-hydroxyisovalerate + NAD+
show the reaction diagram
about 10% of the activity with oxaloacetate at pH 8.2
-
?
alpha-ketomalonate + NADH
?
show the reaction diagram
-
-
-
?
citrate + NAD+
? + NADH
show the reaction diagram
-
-
-
?
hydroxymalonate + NAD+
? + NADH
show the reaction diagram
-
-
-
?
hydroxymalonate + NAD+
? + NADH
show the reaction diagram
-
tartronic acid
-
r
L-lactate + NAD+
? + NADH
show the reaction diagram
-
cMDH less catalytically efficient than against its natural substrate malate
-
?
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
Methanothermobacter thermautotrophicum
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
Methanothermobacter thermautotrophicum
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
Citrus sp.
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
Coccochloris peniocystis
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
Bryophyllum calycinum
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
-
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
Rhodobacter capsulatus B100
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
Rhodobacter capsulatus B100
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
Drosophila melanogaster Oregon K
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
Rattus norvegicus Sprague-Dawley
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
Rattus norvegicus Sprague-Dawley
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
Rhodomicrobium vannielii EY33
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
Rhodomicrobium vannielii EY33
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
Thermus aquaticus YT-1
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
Aspergillus niger B60
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
Drosophila virilis Texmelucan
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
Synechocystis sp. 6803 CF
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
Dictyostelium discoideum NC4
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
Rhodospirillum rubrum 1.1.1
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
Rhodospirillum rubrum 1.1.1
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
Thermus thermophilus AT-62
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
Rhodobacter capsulatus 37b4
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
Rhodocyclus purpureus 6770
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
Rhodocyclus purpureus 6770
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
Thermobifida fusca NCIB 11185
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
Coccochloris peniocystis 1548
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
Thermus aquaticus B
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
Laceyella sacchari NCIB 10486
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
Euglena gracilis SM-ZK
-
-
-
r
meso-tartrate + NAD+
? + NADH
show the reaction diagram
-
-
-
r
meso-tartrate + NAD+
? + NADH
show the reaction diagram
-
-
-
r
nicotinamide 1-N6-ethenoadenine dinucleotide + L-malate
?
show the reaction diagram
-
-
-
-
?
nicotinamide hypoxanthine dinucleotide + L-malate
?
show the reaction diagram
-
-
-
-
?
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
?
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
?
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
Methanothermobacter thermautotrophicum
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
Methanothermobacter thermautotrophicum
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
Citrus sp.
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
-
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
-
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
-
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
-
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
-
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
ir
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
Coccochloris peniocystis
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
?
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
Bryophyllum calycinum
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
?
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
?
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
?
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
?
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
?
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
the ratio of oxaloacetate reduction to malate oxidation is 28.4
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
Rhodobacter capsulatus B100
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
Rhodobacter capsulatus B100
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
Drosophila melanogaster Oregon K
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
Rattus norvegicus Sprague-Dawley
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
Rattus norvegicus Sprague-Dawley
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
Rhodomicrobium vannielii EY33
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
Rhodomicrobium vannielii EY33
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
Thermus aquaticus YT-1
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
Aspergillus niger B60
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
Drosophila virilis Texmelucan
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
Methanospirillum hungatei GPI
-
-
-
ir
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
Synechocystis sp. 6803 CF
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
Dictyostelium discoideum NC4
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
Rhodospirillum rubrum 1.1.1
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
Rhodospirillum rubrum 1.1.1
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
Thermus thermophilus AT-62
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
Rhodobacter capsulatus 37b4
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
Rhodocyclus purpureus 6770
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
Rhodocyclus purpureus 6770
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
Thermobifida fusca NCIB 11185
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
Coccochloris peniocystis 1548
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
Thermus aquaticus B
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
Laceyella sacchari NCIB 10486
-
-
-
r
oxaloacetate + NADH
L-malate + NAD+
show the reaction diagram
Euglena gracilis SM-ZK
-
-
-
r
oxaloacetate + NADH
(S)-malate + NAD+
show the reaction diagram
-
-
-
?
oxaloacetate + NADH
(S)-malate + NAD+
show the reaction diagram
cytosolic enzyme and glycosomal enzyme
-
r
oxaloacetate + NADH + H+
(S)-malate + NAD+
show the reaction diagram
-
-
-
?
oxaloacetate + NADH + H+
(S)-malate + NAD+
show the reaction diagram
-
-
-
?
oxaloacetate + NADH + H+
(S)-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH + H+
(S)-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH + H+
(S)-malate + NAD+
show the reaction diagram
-
-
r
oxaloacetate + NADH + H+
(S)-malate + NAD+
show the reaction diagram
-
-
-
?
oxaloacetate + NADH + H+
(S)-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH + H+
(S)-malate + NAD+
show the reaction diagram
-
-
?
oxaloacetate + NADH + H+
(S)-malate + NAD+
show the reaction diagram
-
-
-
r
oxaloacetate + NADH + H+
(S)-malate + NAD+
show the reaction diagram
-
-
-
?
oxaloacetate + NADH + H+
(S)-malate + NAD+
show the reaction diagram
-
-
-
?
oxaloacetate + NADH + H+
(S)-malate + NAD+
show the reaction diagram
-
-
-
?
oxaloacetate + NADH + H+
(S)-malate + NAD+
show the reaction diagram
-
-
r
oxaloacetate + NADH + H+
(S)-malate + NAD+
show the reaction diagram
the reduction of oxaloacetate with NADH is preferred. Malate is oxidized by NAD+ at 10% of the maximal velocity for the reduction of oxaloacetate with NADH. Maximal activity with NADPH is 10% compared to the activity with NADH
-
r
oxaloacetate + NADH + H+
(S)-malate + NAD+
show the reaction diagram
Rhodopseudomonas palustris f8pt
-
-
-
r
oxaloacetate + NADH + H+
(S)-malate + NAD+
show the reaction diagram
Zea mays Goldener Badischer Landmais
-
-
-
r
oxaloacetate + NADH + H+
(S)-malate + NAD+
show the reaction diagram
Halobacterium salinarum NRC 36014
-
-
-
?
oxaloacetate + NADH + H+
(S)-malate + NAD+
show the reaction diagram
Macromonas bipunctata D-405
-
-
-
r
oxaloacetate + NADH + H+
(S)-malate + NAD+
show the reaction diagram
Haloarcula marismortui DSM 3752
-
-
?
oxaloacetate + NADH + H+
(S)-malate + NAD+
show the reaction diagram
Haloarcula marismortui DSM 3752
-
-
-
?
oxaloacetate + NADH + H+
(S)-malate + NAD+
show the reaction diagram
Haloarcula marismortui DSM 3752
-
-
-
?
oxaloacetate + NADH + H+
(S)-malate + NAD
show the reaction diagram
Haloarcula marismortui, Haloarcula marismortui DSM 3752
-
-
-
?
oxaloglycolate + NAD+
? + NADH
show the reaction diagram
-
-
-
r
p-hydroxyphenylpyruvate + NADH + H+
2-hydroxy-3-(4-hydroxyphenyl)propanoate
show the reaction diagram
-
-
?
phenylpyruvate + NADH
2-hydroxy-3-phenylpropanoate + NAD+
show the reaction diagram
about 30% of the activity with oxaloacetate at pH 8.2
-
?
phenylpyruvate + NADH + H+
2-hydroxy-3-phenylpropanoate + NAD+
show the reaction diagram
-
-
?
pyridine 3-aldehyde adenine dinucleotide + L-malate
?
show the reaction diagram
-
-
-
-
?
pyruvate + NAD+
? + NADH
show the reaction diagram
-
cMDH less catalytically efficient than against its natural substrate malate
-
?
pyruvate + NADH
2-hydroxypropanoate + NAD+
show the reaction diagram
about 25% of the activity with oxaloacetate at pH 8.2
-
?
pyruvate + NADH + H+
(S)-lactate + NAD+
show the reaction diagram
-
wild-type enzyme shows no activity with pyruvate. Mutant enzyme R100Q has considerably higher specificity for pyruvate than for oxaloacetate
-
?
pyruvate + NADH + H+
(S)-lactate + NAD+
show the reaction diagram
Haloarcula marismortui DSM 3752
wild-type enzyme shows no activity with pyruvate. Mutant enzyme R100Q has considerably higher specificity for pyruvate than for oxaloacetate
-
?
thionicotinamide adenine dinucleotide + L-malate
?
show the reaction diagram
-
-
-
-
?
meso-tartrate + NAD+
? + NADH
show the reaction diagram
-
slightly oxidized, 0.82 of the rate for L-malate oxidation
-
r
additional information
?
-
-
D-malate, (+)-tartrate, succinate and L-aspartate are not oxidized
-
-
-
additional information
?
-
-
D-malate, L-tartarate, D-tartarate, hydroxymalonate, dihydroxyfumarate, L-lactate, D-lactate Dl-alpha-hydroxybutyrate, pyruvate, alpha-hydroxypyruvate, alpha-ketoisovalerate and alpha-ketoglutarate are no substrates
-
-
-
additional information
?
-
-
the enzyme is involved in the tricarboxylic acid cycle supplying organic acids as the main source of carbon but not energy
-
-
-
additional information
?
-
the enzyme plays a central role in Crassulacean acid metabolism, less than 10% of the activity with oxaloacetate with the substrates: alpha-ketobutyrate, alpha-ketoisocaproate, alpha-ketovalerate and alpha-ketomethylvalerate
-
-
-
additional information
?
-
-
the dimeric isoform of the enzyme is responsible for Krebs cycle function and the tetrameric isoform is involved in functioning of the glyoxylate cycle
-
-
-
additional information
?
-
the malate-aspartate NADH shuttle components are metabolic longevity regulators required for calorie restriction-mediated life span extension in yeast, the shuttle plays a major role in the activation of the downstream targets of calorie restriction such as Sir2, mechanism and regulation, detailed overview
-
-
-
additional information
?
-
-
MDH1 stabilizes and transactivates p53 protein by binding to p53-responsive elements in the promotor of downstream genes, MDH1 directly regulates p53-dependent apoptosis upon glucose deprivation
-
-
-
additional information
?
-
-
PMDH activity is not essential for photosynthesis in air in Arabidopsis
-
-
-
additional information
?
-
-
the dimeric 74-kDa isozyme is involved in tricarboxylic acid cycle, while the tetrameric 148-kDa isozyme takes part in the citramalate pathway
-
-
-
additional information
?
-
-
the recombinant SaMDH may also use NADPH as a cofactor although it is a highly NAD(H)-specific enzyme. No activity with malate and NADP+ as substrates
-
-
-
additional information
?
-
no substrate: lactate
-
-
-
additional information
?
-
Rhodopseudomonas palustris f8pt
-
the dimeric isoform of the enzyme is responsible for Krebs cycle function and the tetrameric isoform is involved in functioning of the glyoxylate cycle
-
-
-
additional information
?
-
Streptomyces avermitilis MA-4680
-
the recombinant SaMDH may also use NADPH as a cofactor although it is a highly NAD(H)-specific enzyme. No activity with malate and NADP+ as substrates
-
-
-
additional information
?
-
Beggiatoa leptomitiformis D-402
-
the enzyme is involved in the tricarboxylic acid cycle supplying organic acids as the main source of carbon but not energy
-
-
-
additional information
?
-
Rhodobacter sphaeroides 2R
-
the dimeric 74-kDa isozyme is involved in tricarboxylic acid cycle, while the tetrameric 148-kDa isozyme takes part in the citramalate pathway
-
-
-
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
LITERATURE
(Substrate)
COMMENTARY
(Product)
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
(S)-malate + 3-acetylpyridine-adenine dinucleotide
oxaloacetate + reduced 3-acetylpyridine-adenine dinucleotide + H+
show the reaction diagram
-
can also use 3-acetylpyridine-adenine as cofactor
-
r
(S)-malate + NAD(P)+
oxaloacetate + NAD(P)H
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
P61889
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
P22133
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
Q9K3J3
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
Pontonia pinnophylax
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
Q07841
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
P61889
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
A3DSX0
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
A3DSX0
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
Q9LKA3, Q9ZP06
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
Q6C5X9, Q6C8V3
-
-
?
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
F1C7I4
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
Q90YZ7, Q90YZ8, Q90YZ9
mitochondrial enzyme form mMDH functions in citric acid cycle and in the malate-aspartate shuttle
-
?
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
O15769
mitochondrial enzyme, Krebs cycle
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
Q25QU7
malate dehydrogenase is an oligomeric enzyme that catalyzes the reversible oxidation of malate to oxaloacetate in the presence of NAD+, MDH is an essential metabolic enzyme in the citric acid cycle
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
Q4VVC2
the NAD-dependent mitochondrial malate dehydrogenase plays pivotal roles in tricarboxylic acid and is crucial for the survival and pathogenecity of parasites
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
the peroxisomal malate dehydrogenase functions in beta-oxidation, serving to reoxidize NADH, but not in the glyoxylate cycle
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
-
highly specific for oxaloacetate and malate
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
Streptomyces avermitilis MA-4680
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
Zea mays Goldener Badischer Landmais
-
-
-
r
(S)-malate + NAD+
oxaloacetate + NADH + H+
show the reaction diagram
Zea mays VA35
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram
-
-
-
r
malate + NAD+
oxaloacetate + NADH
show the reaction diagram