Information on EC 1.1.1.297 - limonene-1,2-diol dehydrogenase

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The expected taxonomic range for this enzyme is: Rhodococcus erythropolis

EC NUMBER
COMMENTARY hide
1.1.1.297
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RECOMMENDED NAME
GeneOntology No.
limonene-1,2-diol dehydrogenase
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REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(1R,2R,4S)-menth-8-ene-1,2-diol + NAD+ = (1R,4S)-1-hydroxymenth-8-en-2-one + NADH + H+
show the reaction diagram
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(1S,2S,4R)-menth-8-ene-1,2-diol + NAD+ = (1S,4R)-1-hydroxymenth-8-en-2-one + NADH + H+
show the reaction diagram
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menth-8-ene-1,2-diol + NAD+ = 1-hydroxymenth-8-en-2-one + NADH + H+
show the reaction diagram
general reaction
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PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
Limonene and pinene degradation
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limonene degradation I (D-limonene)
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limonene degradation II (L-limonene)
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SYSTEMATIC NAME
IUBMB Comments
menth-8-ene-1,2-diol:NAD+ oxidoreductase
While the enzyme from the Gram-positive bacterium Rhodococcus erythropolis DCL14 can use both (1S,2S,4R)- and (1R,2R,4S)-menth-8-ene-1,2-diol as substrate, activity is higher with (1S,2S,4R)-menth-8-ene-1,2-diol as substrate.
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
DCL14
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Manually annotated by BRENDA team
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(1R,2R,4S)-limonene-1,2-diol + NAD+
(1R,4S)-1-hydroxy-2-oxolimonene + (1R,2S,4S)-limonene-1,2-diol + NADH + H+
show the reaction diagram
(1S,2S,4R)-limonene-1,2-diol + NAD+
(1S,4R)-1-hydroxy-2-oxolimonene + NADH + H+
show the reaction diagram
additional information
?
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NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
additional information
?
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