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Acidosis
Hyperlipemia and ketonuria in an alpaca and a llama.
Acquired Immunodeficiency Syndrome
Modern diets and diseases: NO-zinc balance. Under Th1, zinc and nitrogen monoxide (NO) collectively protect against viruses, AIDS, autoimmunity, diabetes, allergies, asthma, infectious diseases, atherosclerosis and cancer.
Adenoviridae Infections
Combination therapy with lamivudine and adenovirus causes transient suppression of chronic woodchuck hepatitis virus infections.
Albuminuria
Redox state-dependent and sorbitol accumulation-independent diabetic albuminuria in mice with transgene-derived human aldose reductase and sorbitol dehydrogenase deficiency.
Anemia
Acute hemoperitoneum in horses: a review of 19 cases (1992-2003).
Anemia
Heinz body anemia and methemoglobinemia in ponies given red maple (acer rubrum L.) leaves.
Anemia
NTP Toxicology and Carcinogenesis Studies of Chloroprene (CAS No. 126-99-8) in F344/N Rats and B6C3F1 Mice (Inhalation Studies).
Anemia
Prechronic inhalation toxicity studies of 2-mercaptobenzimidazole (2-MBI) in F344/N rats.
Anemia
[Changes in serum and liver sorbitol dehydrogenase during experimentally induced immunohemolytic anemia.]
Atherosclerosis
[Effect of sodium fluoride on the activity of sorbitol dehydrogenase in plasma and liver of rabbits with experimental atherosclerosis]
Azotemia
Acute hemoperitoneum in horses: a review of 19 cases (1992-2003).
Azotemia
Hyperlipemia and ketonuria in an alpaca and a llama.
Carcinoma
[Laboratory tests in the diagnosis of stomach cancer]
Carcinoma, Hepatocellular
Metabolism of xylitol and glucose in rats bearing hepatocellular.
Cataract
A fluorimetric method for red blood cell sorbitol dehydrogenase activity.
Cataract
Aldose reductase and sorbitol dehydrogenase distribution in substructures of normal and diabetic rat lens.
Cataract
Anticataract activity of analogs of a sorbitol dehydrogenase inhibitor.
Cataract
Effect of sorbitol dehydrogenase inhibition on sugar cataract formation in galactose-fed and diabetic rats.
Cataract
Lens cholesterol biosynthesis inhibition: A common mechanism of cataract formation in laboratory animals by pharmaceutical products.
Cataract
Lens sorbitol dehydrogenase deficiency in a patient with congenital cataract.
Cataract
Membrane-bound sorbitol dehydrogenase in human red blood cells. Studies in normal subjects and in enzyme-deficient subjects with congenital cataracts.
Cataract
Red blood cell sorbitol dehydrogenase deficiency in a family with cataracts.
Cataract
Reversible and irreversible inhibition of sheep liver sorbitol dehydrogenase with Cibacron Blue 3GA and Eriochrome Black T.
Cataract
Screening for red blood cell sorbitol dehydrogenase deficiency in patients with diabetes or cataracts.
Cataract
Sorbitol dehydrogenase deficiency in a family with congenital cataracts.
Cataract
Sorbitol dehydrogenase deficiency in several pig tissues: potential implications for studies of experimental diabetes.
Cataract
Studies on cataractogenesis in humans and in rats with alloxan-induced diabetes. II. Histochemical evaluation of lenticular enzymes.
Cataract
Synergistic effect of osmotic and oxidative stress in slow-developing cataract formation.
Cataract
The sorbitol pathway in the human lens: aldose reductase and polyol dehydrogenase.
Charcot-Marie-Tooth Disease
Biallelic SORD pathogenic variants cause Chinese patients with distal hereditary motor neuropathy.
Chemical and Drug Induced Liver Injury
Determination of sorbitol dehydrogenase in microsamples of human serum.
Chemical and Drug Induced Liver Injury
[Evaluation of severity of toxic hepatitis in acute poisoning with chlorinated hydrocarbons after changes of the activity of aminotransferases and sorbitol dehydrogenase]
Cholera
Frontal affinity chromatography-mass spectrometry assay technology for multiple stages of drug discovery: applications of a chromatographic biosensor.
Cholestasis
14-Week toxicity and cell proliferation of methyleugenol administered by gavage to F344 rats and B6C3F1 mice.
Cholestasis
[Extrahepatic cholestasis due to pancreas fibrosis in a trotter]
Coinfection
[Effect of litonit and teturam on the course of biochemical processes in infectious inflammatory lesions of the kidneys in alcoholized animals]
Dehydration
Physiological and molecular responses for long term salinity stress in common fig (Ficus carica L.).
Diabetes Complications
Cloning, sequencing, and determination of the sites of expression of mouse sorbitol dehydrogenase cDNA.
Diabetes Complications
Effect of sorbitol dehydrogenase inhibition on sugar cataract formation in galactose-fed and diabetic rats.
Diabetes Complications
Glycation and inactivation of sorbitol dehydrogenase in normal and diabetic rats.
Diabetes Complications
Increased white cell aldose reductase mRNA levels in diabetic patients.
Diabetes Complications
Inhibition of sorbitol dehydrogenase by nucleosides and nucleotides.
Diabetes Complications
Interaction between osmotic and oxidative stress in diabetic precataractous lens: studies with a sorbitol dehydrogenase inhibitor.
Diabetes Complications
Is sorbitol dehydrogenase gene expression affected by streptozotocin-diabetes in the rat?
Diabetes Complications
Modern diets and diseases: NO-zinc balance. Under Th1, zinc and nitrogen monoxide (NO) collectively protect against viruses, AIDS, autoimmunity, diabetes, allergies, asthma, infectious diseases, atherosclerosis and cancer.
Diabetes Complications
Search for non-acidic ALR2 inhibitors: Evaluation of flavones as targeted agents for the management of diabetic complications.
Diabetes Complications
Studies on clinical markers of diabetes mellitus. 6. Red blood cell sorbitol and diabetic complications.
Diabetes Complications
[Clinical significance of erythrocyte sorbitol, sorbitol dehydrogenase and glyceraldehyde reductase in diabetic complications]
Diabetes Complications
[Effects of transgenic human aldose reductase and sorbitol dehydrogenase deficiency on diabetes complications]
Diabetes Mellitus
Aldose reductase and sorbitol dehydrogenase activities in diabetic brain: in vivo kinetic studies using 19F 3-FDG NMR in rats.
Diabetes Mellitus
Comparison of the effects of inhibitors of aldose reductase and sorbitol dehydrogenase on neurovascular function, nerve conduction and tissue polyol pathway metabolites in streptozotocin-diabetic rats.
Diabetes Mellitus
Inhibition of sorbitol dehydrogenase by nucleosides and nucleotides.
Diabetes Mellitus
Plasma sorbitol dehydrogenase in diabetic subjects with or without vascular complications.
Diabetes Mellitus
[Erythrocyte sorbitol, sorbitol dehydrogenase (SDH) and glyceraldehyde reductase (GAR) in diabetes mellitus]
Diabetes Mellitus
[Erythrocyte sorbitol, sorbitol dehydrogenase (SDH), and glyceraldehyde reductase (GAR) in diabetes mellitus]
Diabetes Mellitus
[Normalization of sorbitol dehydrogenase activity--an important factor in the treatment of neuropathies and angiopathies in patients with diabetes mellitus]
Diabetes Mellitus, Experimental
HISTOCHEMICAL STUDY ON THE ACTIVITY OF SORBITOL DEHYDROGENASE IN RATS WITH EXPERIMENTAL DIABETES MELLITUS.
Diabetes Mellitus, Experimental
[Use of naphthylimidoacetic acid in experimental diabetes mellitus in rats]
Diabetes Mellitus, Type 1
Screening for red blood cell sorbitol dehydrogenase deficiency in patients with diabetes or cataracts.
Diabetic Nephropathies
Elevated activity of transcription factor nuclear factor of activated T-cells 5 (NFAT5) and diabetic nephropathy.
Diabetic Neuropathies
Effect of sorbitol dehydrogenase inhibition on experimental diabetic autonomic neuropathy.
Diabetic Neuropathies
Evaluation of a sorbitol dehydrogenase inhibitor on diabetic peripheral nerve metabolism: a prevention study.
Diabetic Retinopathy
Aldo-keto reductase and sorbitol dehydrogenase enzymes in Egyptian diabetic patients with and without proliferative diabetic retinopathy.
Diabetic Retinopathy
Association between sorbitol dehydrogenase gene polymorphisms and type 2 diabetic retinopathy.
Diabetic Retinopathy
Association study of sorbitol dehydrogenase -888G>C polymorphism with type 2 diabetic retinopathy in Caucasian-Brazilians.
Diabetic Retinopathy
Polymorphisms of sorbitol dehydrogenase (SDH) gene and susceptibility to diabetic retinopathy.
Digestive System Diseases
[The biochemical markers of hepatobiliary function in children under environmental pollution].
Fascioliasis
Response of goats to repeated infections with Fasciola gigantica.
Fascioliasis
The use of haemoglobin, packed-cell volume and serum sorbitol dehydrogenase as indicators of the development of fascioliasis in sheep.
Fatty Liver
Biochemical changes associated with the fatty liver syndrome in cows.
galactokinase deficiency
Cataract and metabolic disease.
Galactosemias
Cataract and metabolic disease.
Glomerulonephritis
[Lactate, malate and sorbitol dehydrogenase and serum urocaninase activity in children with acute diffuse glomerulonephritis]
Hepatitis
Serum alcohol dehydrogenase activity in liver diseases.
Hepatitis
Studies on some serum enzyme levels in various liver diseases.
Hepatitis
[Activity of the marker liver enzymes under the conditions of toxic hepatitis and alimentary deprivation of protein].
Hepatitis
[Blood and urine values of sorbitol dehydrogenase in viral hepatitis in childhood]
Hepatitis
[DIAGNOSTIC VALUE OF SORBITOL DEHYDROGENASE IN CASES OF ACUTE INFANTILE HEPATITIS.]
Hepatitis
[Serum sorbitol dehydrogenase in viral hepatitis]
Hepatitis
[Studies on the diagnostic value of various enzymatic activties in icterogenic hepatitis of infancy. II. Sorbitol dehydrogenase, guanase and argininosuccinate lyase]
Hepatitis A
[Drug-induced hepatitis]
Hepatitis A
[ON THE IMPORTANCE OF DETERMINING THE ACTIVITY OF SORBITOL DEHYDROGENASE IN INFECTIOUS HEPATITIS.]
Hepatitis, Alcoholic
Studies on some serum enzyme levels in various liver diseases.
Hepatitis, Chronic
Studies on some serum enzyme levels in various liver diseases.
Hypercholesterolemia
Hyperlipemia and ketonuria in an alpaca and a llama.
Hyperglycemia
Association study of sorbitol dehydrogenase -888G>C polymorphism with type 2 diabetic retinopathy in Caucasian-Brazilians.
Hyperglycemia
Measurements of tissue sorbitol in diabetes mellitus: enzyme method versus gas-liquid chromatography.
Hyperthyroidism
Liver alcohol and sorbitol dehydrogenase activities in hypo- and hyperthyroid rats.
Hyperthyroidism
[Erythrocyte sorbitol levels in patients with thyrotoxicosis]
Hypertriglyceridemia
Hyperlipemia and ketonuria in an alpaca and a llama.
Hypocalcemia
Acute hemoperitoneum in horses: a review of 19 cases (1992-2003).
Hypoproteinemia
Acute hemoperitoneum in horses: a review of 19 cases (1992-2003).
Infections
Acquired resistance to Fasciola hepatica in cattle using a purified adult worm antigen.
Infections
Experimental paratuberculosis (Johne's disease)--studies on biochemical parameters in cattle.
Infections
Protective effect of irradiated metacercariae of Fasciola gigantica and irradiated cercariae of Schistosoma bovis against fascioliasis in goats.
Infections
Response of goats to repeated infections with Fasciola gigantica.
Infections
Susceptibility to homologous reinfection with Fasciola gigantica in goats.
Infections
The effect of experimental fascioliasis on the pharmacokinetics of antipyrine and sulphadimidine in desert sheep.
Infections
The effects of fascioliasis on the activities of some drug-metabolizing enzymes in desert sheep liver.
Infections
Use of physiologic variables to predict milk yield after clinical mastitis in dairy cattle.
Infections
[Relation between an increase in plasma sorbitol dehydrogenase activity and hepatocellular lesions in infections by Craig MHV-3 virus.]
Insulin Resistance
Effects of S-Allylcysteine on Biomarkers of the Polyol Pathway in Rats with Type 2 Diabetes.
Ketosis
Hepatic lipidosis in anorectic, lactating holstein cattle: a retrospective study of serum biochemical abnormalities.
Ketosis
Hyperlipemia and ketonuria in an alpaca and a llama.
l-iditol 2-dehydrogenase deficiency
A fluorimetric method for red blood cell sorbitol dehydrogenase activity.
l-iditol 2-dehydrogenase deficiency
Aberrant mRNA splicing causes sorbitol dehydrogenase deficiency in C57BL/LiA mice.
l-iditol 2-dehydrogenase deficiency
Cataract and metabolic disease.
l-iditol 2-dehydrogenase deficiency
Effects of sorbitol dehydrogenase deficiency on nerve conduction in experimental diabetic mice.
l-iditol 2-dehydrogenase deficiency
Lens sorbitol dehydrogenase deficiency in a patient with congenital cataract.
l-iditol 2-dehydrogenase deficiency
Plasma polyol levels in patients with cataract.
l-iditol 2-dehydrogenase deficiency
Red blood cell sorbitol dehydrogenase deficiency in a family with cataracts.
l-iditol 2-dehydrogenase deficiency
Redox state-dependent and sorbitol accumulation-independent diabetic albuminuria in mice with transgene-derived human aldose reductase and sorbitol dehydrogenase deficiency.
l-iditol 2-dehydrogenase deficiency
Screening for red blood cell sorbitol dehydrogenase deficiency in patients with diabetes or cataracts.
l-iditol 2-dehydrogenase deficiency
Sorbitol dehydrogenase deficiency in a family with congenital cataracts.
l-iditol 2-dehydrogenase deficiency
Sorbitol dehydrogenase deficiency in several pig tissues: potential implications for studies of experimental diabetes.
l-iditol 2-dehydrogenase deficiency
[Effects of transgenic human aldose reductase and sorbitol dehydrogenase deficiency on diabetes complications]
Leukemia
[Sorbitol dehydrogenase activity in the blood plasma of children with acute leukemia and lymphogranulomatosis]
Lipidoses
Hepatic lipidosis in anorectic, lactating holstein cattle: a retrospective study of serum biochemical abnormalities.
Liver Abscess, Amebic
Studies on some serum enzyme levels in various liver diseases.
Liver Diseases
Hepatic lipidosis in anorectic, lactating holstein cattle: a retrospective study of serum biochemical abnormalities.
Liver Diseases
Letter: Sorbitol dehydrogenase in the diagnosis of liver disease of ruminants.
Liver Diseases
SORBITOL DEHYDROGENASE IN THE DIAGNOSIS OF LIVER DISEASE.
Liver Diseases
[Clinical value of the determination of plasma sorbitol dehydrogenase activity in liver disease.]
Liver Diseases
[Importance and limitations of sorbitol dehydrogenase in the diagnosis of liver diseases of various types.]
Liver Diseases
[On the influence of surgery on the biliary system, especially in liver diseases, on the serum level of the enzymes sorbitol dehydrogenase, glutamic-pyruvic transaminase, lactate dehydrogenase and glutamic dehydrogenase.]
Liver Diseases
[Pathological occurrence of sorbitol dehydrogenase in blood in liver diseases.]
Liver Diseases
[SERUM ENZYMES IN THE DIAGNOSIS OF LIVER DISEASE. III. SORBITOL DEHYDROGENASE, ALDOLASES, ISOCITRIC DEHYDROGENASE AND TRANSAMINASES.]
Liver Diseases
[SERUM SORBITOL DEHYDROGENASE ACTIVITY IN LIVER DISEASE PATIENTS.]
Liver Diseases
[SORBITOL DEHYDROGENASE ACTIVITY IN EXPERIMENTAL LIVER DISEASES.]
Liver Diseases
[SORBITOL DEHYDROGENASE ACTIVITY OF THE BLOOD IN LIVER DISEASES.]
Liver Diseases
[Sorbitol dehydrogenase in liver diseases.]
Liver Diseases
[SORBITOL DEHYDROGENASE, FRUCTOSE-1-PHOSPHATE ALDOLASE AND MALATE DEHYDROGENASE ACTIVITY IN SOME LIVER DISEASES.]
Liver Diseases
[The information value of determining serum sorbitol dehydrogenase activity in liver diseases]
Liver Diseases
[The role of sorbitol dehydrogenase in the diagnosis of liver diseases.]
Liver Failure
Hepatic failure leads to lethality of chlordecone-amplified hepatotoxicity of carbon tetrachloride.
Lung Injury
Potentiation of carbon tetrachloride-induced hepatotoxicity and pneumotoxicity by pyridine.
Lymphopenia
Acute hemoperitoneum in horses: a review of 19 cases (1992-2003).
Massive Hepatic Necrosis
Evidence for the involvement of a reperfusion injury in galactosamine/endotoxin-induced hepatitis in mice.
Mastitis
Use of physiologic variables to predict milk yield after clinical mastitis in dairy cattle.
Muscular Dystrophies
[Serum enzyme dynamics in progressive muscular dystrophies]
Myocardial Infarction
Polyol pathway impairs the function of SERCA and RyR in ischemic-reperfused rat hearts by increasing oxidative modifications of these proteins.
Myocardial Infarction
[Enzyme diagnosis of liver dysfunction in acute myocardial infarct and its complications]
Neoplasms
Chlorella vulgaris or Spirulina platensis mitigate lead acetate-induced testicular oxidative stress and apoptosis with regard to androgen receptor expression in rats.
Neoplasms
Isozyme phenotypes of polyoma virus tumors in mice.
Neoplasms
Metabolism of xylitol and glucose in rats bearing hepatocellular.
Neurilemmoma
Sorbitol accumulation and transmembrane efflux in osmotically stressed JS1 schwannoma cells.
Neuromuscular Diseases
[Sorbitol dehydrogenase activity in the serum of some neuromuscular diseases]
Pre-Eclampsia
Analysis of the Epigenome in Multiplex Pre-eclampsia Families Identifies SORD, DGKI, and ICA1 as Novel Candidate Risk Genes.
Retinal Artery Occlusion
Gene deletion and pharmacological inhibition of aldose reductase protect against retinal ischemic injury.
Rheumatic Fever
[Sorbitol dehydrogenase (SDH) activity of the blood in chronic inflammatory rheumatism]
Thrombocytopenia
Acute hemoperitoneum in horses: a review of 19 cases (1992-2003).
Thrombocytopenia
NTP Toxicology and Carcinogenesis Studies of Chloroprene (CAS No. 126-99-8) in F344/N Rats and B6C3F1 Mice (Inhalation Studies).
Thyrotoxicosis
[Erythrocyte sorbitol levels in patients with thyrotoxicosis]
Tuberous Sclerosis
Malignant pleural effusion cells show aberrant glucose metabolism gene expression.
Viremia
Correlation of virus and host response markers with circulating immune complexes during acute and chronic woodchuck hepatitis virus infection.
Virus Diseases
The prevalence of elevated gamma-glutamyltransferase and sorbitol dehydrogenase activity in racing Thoroughbreds and their associations with viral infection.
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Dooley, J.F.; Turnquist, L.J.; Racich, L.
Kinetic determination of serum sorbitol dehydrogenase activity with a centrifugal analyzer
Clin. Chem.
25
2026-2029
1979
Canis lupus familiaris, Homo sapiens, Mus musculus, Rattus norvegicus
brenda
Gerlach, U.; Hiby, W.
Sorbit-Dehydrogenase
Methods Enzym. Anal. , 3rd Ed. (Bergmeyer, H. U. , ed. )
1
601-606
1974
Homo sapiens, Rattus norvegicus
-
brenda
Maret, W.
Human sorbitol dehydrogenase - a secondary alcohol dehydrogenase with distinct pathophysiological roles, pH dependent kinetic studies
Adv. Exp. Med. Biol.
383-393
1996
Homo sapiens
brenda
Darmanin, C.; Iwata, T.; Carper, D.A.; Sparrow, L.G.; Chung, R.P.; El-Kabbani, O.
Expression, purification and preliminary crystallographic analysis of human sorbitol dehydrogenase
Acta Crystallogr. Sect. D
59
558-560
2003
Homo sapiens
brenda
El-Kabbani, O.; Darmanin, C.; Chung, R.P.
Sorbitol dehydrogenase: structure, function and ligand design
Curr. Med. Chem.
11
465-476
2004
Ovis aries, Homo sapiens, Mammalia, Rattus norvegicus
brenda
Pauly, T.A.; Ekstrom, J.L.; Beebe, D.A.; Chrunyk, B.; Cunningham, D.; Griffor, M.; Kamath, A.; Lee, S.E.; Madura, R.; McGuire, D.; Subashi, T.; Wasilko, D.; Watts, P.; Mylari, B.L.; Oates, P.J.; Adams, P.D.; Rath, V.L.
X-ray crystallographic and kinetic studies of human sorbitol dehydrogenase
Structure
11
1071-1085
2003
Homo sapiens (Q00796), Homo sapiens
brenda
Lanaspa, M.A.; Andres-Hernando, A.; Rivard, C.J.; Dai, Y.; Li, N.; Berl, T.
ZAC1 is up-regulated by hypertonicity and decreases sorbitol dehydrogenase expression, allowing accumulation of sorbitol in kidney cells
J. Biol. Chem.
284
19974-19981
2009
Homo sapiens, Mus musculus
brenda
Landau, Z.; Novotny, M.J.; Preston, G.M.; Wright, K.; Freeman, T.; Dai, H.; Thompson, J.; Oates, P.J.; Calle, R.A.
Pharmacokinetics, pharmacodynamics, tolerability, and safety of a novel sorbitol dehydrogenase inhibitor in healthy participants
J. Clin. Pharmacol.
50
521-530
2010
Homo sapiens
brenda