Information on EC 1.1.1.100 - 3-oxoacyl-[acyl-carrier-protein] reductase

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The enzyme appears in viruses and cellular organisms

EC NUMBER
COMMENTARY
1.1.1.100
-
RECOMMENDED NAME
GeneOntology No.
3-oxoacyl-[acyl-carrier-protein] reductase
PATHWAY
KEGG Link
MetaCyc Link
8-amino-7-oxononanoate biosynthesis I
-
Biosynthesis of unsaturated fatty acids
-
Biotin metabolism
-
cis-dodecenoyl biosynthesis
-
cis-vaccenate biosynthesis
-
docosahexanoate biosynthesis I
-
docosahexanoate biosynthesis II
-
Fatty acid biosynthesis
-
fatty acid elongation -- saturated
-
Metabolic pathways
-
mycolate biosynthesis
-
octanoyl-ACP biosynthesis (mitochondria, yeast)
-
palmitate biosynthesis I (animals and fungi)
-
palmitate biosynthesis II (bacteria and plants)
-
palmitoleate biosynthesis I
-
petroselinate biosynthesis
-
stearate biosynthesis II (bacteria and plants)
-
stearate biosynthesis III (fungi)
-
SYSTEMATIC NAME
IUBMB Comments
(3R)-3-hydroxyacyl-[acyl-carrier protein]:NADP+ oxidoreductase
Exhibits a marked preference for acyl-carrier-protein derivatives over CoA derivatives as substrates.
SYNONYMS
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
3-ketoacyl acyl carrier protein reductase
-
-
-
-
3-ketoacyl-(acyl-carrier-protein) reductase
P50941
-
3-ketoacyl-ACP reductase
A5HIF6
-
3-ketoacyl-ACP(CoA) reductase
-
-
3-ketoacyl-acyl carrier protein reductase
-
-
-
-
3-ketoacyl-acyl carrier protein reductase
-
-
3-ketoacyl-acyl carrier protein reductase
A5HIF6
-
3-ketoacyl-acyl carrier protein reductase
Q4AE87
-
3-ketoacyl-[acyl-carrier-protein] reductase
Q31QF3
-
3-oxoacyl-(acyl carrier protein) reductase
Q81JG6
-
3-oxoacyl-ACP reductase
Q86RB1
-
3-oxoacyl-ACP reductase
-
-
3-oxoacyl-AcpM reductase
O53665, P0A5Y4
-
3-oxoacyl-thioester reductase
-
-
3-oxoacyl-thioester reductase
-
-
3-oxoacyl-[ACP]reductase
-
-
-
-
beta-ketoacyl acyl carrier protein (ACP) reductase
-
-
-
-
beta-ketoacyl acyl carrier protein reductase
-
-
beta-ketoacyl acyl carrier protein reductase
-
-
beta-ketoacyl reductase
-
-
-
-
beta-ketoacyl reductase
-
-
beta-ketoacyl reductase
-
-
beta-ketoacyl reductase
-
-
beta-ketoacyl thioester reductase
-
-
-
-
beta-ketoacyl-ACP reductase
-
-
-
-
beta-ketoacyl-ACP reductase
-
-
beta-ketoacyl-ACP reductase
Acinetobacter calcoaceticus 25001
-
-
-
beta-ketoacyl-ACP reductase
-
-
beta-ketoacyl-ACP reductase
Enterobacter aerogenes 45102
-
-
-
beta-ketoacyl-ACP reductase
-
-
beta-ketoacyl-ACP reductase
Enterobacter cloacae 45301
-
-
-
beta-ketoacyl-ACP reductase
-
-
beta-ketoacyl-ACP reductase
-
-
beta-ketoacyl-ACP reductase
-
-
beta-ketoacyl-ACP reductase
Haloarcula hispanica AS2049, Haloarcula hispanica CGMCC1.2049
-
-
-
beta-ketoacyl-ACP reductase
-
-
beta-ketoacyl-ACP reductase
-
-
beta-ketoacyl-ACP reductase
-
-
beta-ketoacyl-ACP reductase
-
-
beta-ketoacyl-ACP reductase
-
-
beta-ketoacyl-ACP reductase
-
-
beta-ketoacyl-ACP reductase
-
-
beta-ketoacyl-ACP reductase
Pseudomonas aeruginosa ATCC27853
-
-
-
beta-ketoacyl-ACP reductase
Salmonella enterica subsp. enterica serovar Typhi H901
-
-
-
beta-ketoacyl-ACP reductase
Serratia marcescens 41002
-
-
-
beta-ketoacyl-ACP reductase
Shigella sonnei 51592
-
-
-
beta-ketoacyl-ACP reductase
-
-
beta-ketoacyl-ACP reductase
Staphylococcus aureus ATCC25923
-
-
-
beta-ketoacyl-ACP reductase
-
-
beta-ketoacyl-ACP reductase
-
-
beta-ketoacyl-ACP reductase
-
-
beta-ketoacyl-acyl carrier protein reductase
-
-
-
-
beta-ketoacyl-acyl carrier protein reductase
-
-
beta-ketoacyl-acyl carrier protein reductase
-
-
beta-ketoacyl-acyl carrier protein reductase
-
-
beta-ketoacyl-[acyl carrier protein] reductase
-
-
beta-ketoacyl-[acyl-carrier protein] (ACP) reductase
-
-
-
-
FabG
Acinetobacter calcoaceticus 25001
-
-
-
FabG
Enterobacter aerogenes 45102
-
-
-
FabG
Enterobacter cloacae 45301
-
-
-
FabG
Pseudomonas aeruginosa ATCC27853
-
-
-
FabG
A5HIF6
-
FabG
Q4AE87
-
FabG
P50941
gene name
FabG
Salmonella enterica subsp. enterica serovar Typhi H901
-
-
-
FabG
Serratia marcescens 41002
-
-
-
FabG
Shigella sonnei 51592
-
-
-
FabG
Staphylococcus aureus ATCC25923
-
-
-
FabG1
Haloarcula hispanica AS2049, Haloarcula hispanica CGMCC1.2049
-
-
-
NADPH-specific 3-oxoacyl-[acylcarrier protein]reductase
-
-
-
-
PHA-specific acetoacetyl-CoA reductase
-
-
PHA-specific acetoacetyl-CoA reductase
Haloarcula hispanica AS2049, Haloarcula hispanica CGMCC1.2049
-
-
-
PHA-specific acetoacetyl-CoA reductase
-
-
PhaB
Haloarcula hispanica AS2049, Haloarcula hispanica CGMCC1.2049
-
-
-
polyhydroxyalkanoate-specific acetoacetyl coenzyme A reductase
-
-
polyhydroxyalkanoate-specific acetoacetyl coenzyme A reductase
Haloarcula hispanica AS2049, Haloarcula hispanica CGMCC1.2049
-
-
-
polyhydroxyalkanoate-specific acetoacetyl coenzyme A reductase
-
-
reductase, 3-oxoacyl-[acyl carrier protein]
-
-
-
-
CAS REGISTRY NUMBER
COMMENTARY
37250-34-3
-
ORGANISM
COMMENTARY
LITERATURE
SEQUENCE CODE
SEQUENCE DB
SOURCE
Acinetobacter calcoaceticus 25001
strain 25001
-
-
Manually annotated by BRENDA team
isoform FabG
-
-
Manually annotated by BRENDA team
rapeseed
-
-
Manually annotated by BRENDA team
strain 45102
-
-
Manually annotated by BRENDA team
Enterobacter aerogenes 45102
strain 45102
-
-
Manually annotated by BRENDA team
strain 45301
-
-
Manually annotated by BRENDA team
Enterobacter cloacae 45301
strain 45301
-
-
Manually annotated by BRENDA team
strains ATCC29212 and 775
-
-
Manually annotated by BRENDA team
; strains ATCC 25922 and 26
-
-
Manually annotated by BRENDA team
strain AS2049
-
-
Manually annotated by BRENDA team
Haloarcula hispanica AS2049
strain AS2049
-
-
Manually annotated by BRENDA team
strains ATCC700603 and 14
-
-
Manually annotated by BRENDA team
ssp. lactis IL 1403
-
-
Manually annotated by BRENDA team
avocado
-
-
Manually annotated by BRENDA team
gene fabG
SwissProt
Manually annotated by BRENDA team
gene fabG, no isozymes
-
-
Manually annotated by BRENDA team
strains ATCC27853 and 17
-
-
Manually annotated by BRENDA team
Pseudomonas aeruginosa ATCC27853
ATCC27853
-
-
Manually annotated by BRENDA team
strain 61-3, non-pathogenic strain from soil, gene fabG
SwissProt
Manually annotated by BRENDA team
Salmonella enterica subsp. enterica serovar Typhi H901
strain H901
-
-
Manually annotated by BRENDA team
strain 41002
-
-
Manually annotated by BRENDA team
Serratia marcescens 41002
strain 41002
-
-
Manually annotated by BRENDA team
strain 51592
-
-
Manually annotated by BRENDA team
Shigella sonnei 51592
strain 51592
-
-
Manually annotated by BRENDA team
strains ATCC29213, 15 and 05-3
-
-
Manually annotated by BRENDA team
Staphylococcus aureus ATCC25923
ATCC25923
-
-
Manually annotated by BRENDA team
strains ATCC12228, 04-5 and 05-1
-
-
Manually annotated by BRENDA team
alpha-haemolytic strain 32213-7 and beta-haemolytic strain 32210-20
-
-
Manually annotated by BRENDA team
PDB
SCOP
CATH
ORGANISM
Acholeplasma laidlawii (strain PG-8A)
Aquifex aeolicus (strain VF5)
Aquifex aeolicus (strain VF5)
Bacillus subtilis (strain 168)
Bacillus subtilis (strain 168)
Brucella abortus (strain 2308)
Brucella abortus (strain 2308)
Brucella abortus (strain 2308)
Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Brucella suis (strain ATCC 23445 / NCTC 10510)
Burkholderia multivorans (strain ATCC 17616 / 249)
Burkholderia multivorans (strain ATCC 17616 / 249)
Burkholderia multivorans (strain ATCC 17616 / 249)
Burkholderia pseudomallei (strain 1710b)
Cupriavidus taiwanensis (strain R1 / LMG 19424)
Escherichia coli (strain K12)
Escherichia coli (strain K12)
Escherichia coli (strain K12)
Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Francisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4)
Helicobacter pylori (strain ATCC 700392 / 26695)
Helicobacter pylori (strain ATCC 700392 / 26695)
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra)
Plasmodium falciparum (isolate 3D7)
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Rhizobium meliloti (strain 1021)
Rhizobium meliloti (strain 1021)
Rhizobium meliloti (strain 1021)
Rhizobium meliloti (strain 1021)
Rhizobium meliloti (strain 1021)
Rhizobium meliloti (strain 1021)
Rickettsia felis (strain ATCC VR-1525 / URRWXCal2)
Rickettsia prowazekii (strain Madrid E)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Staphylococcus aureus (strain Mu50 / ATCC 700699)
Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Synechococcus elongatus (strain PCC 7942)
Synechococcus elongatus (strain PCC 7942)
Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Vibrio cholerae serotype O1 (strain MJ-1236)
Vibrio cholerae serotype O1 (strain MJ-1236)
Vibrio cholerae serotype O1 (strain MJ-1236)
Vibrio cholerae serotype O1 (strain MJ-1236)
TEMPERATURE STABILITY
TEMPERATURE STABILITY MAXIMUM
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
30
-
-
wild-type enzyme: about 15% loss of activity after 15 min, mutant enzyme E233K: about 60% loss of activity after 10 min,mutant enzyme A164T: about 20% loss of activity after 15 min, mutant enzyme A154T/E233K: about 80% loss of activity after 15 min
37
-
-
wild-type enzyme: about 40% loss of activity after 15 min, mutant enzyme E233K: about 90% loss of activity after 10 min, mutant enzyme A164T: about 25% loss of activity after 15 min, mutant enzyme A154T/E233K: about 80% loss of activity after 5 min
45
-
-
wild-type enzyme: about 70% loss of activity after 15 min, mutant enzyme E233K: complete loss of activity after 10 min, mutant enzyme A164T: about 60% loss of activity after 15 min, mutant enzyme A154T/E233K: complete loss of activity after 5 min
STORAGE STABILITY
ORGANISM
UNIPROT ACCESSION NO.
LITERATURE
27C, 100 mM potassium phosphate buffer, 13% loss of activity after 24 h
-
4C, 100 mM potassium phosphate, 52% loss of activity after 24 h
-
-20C, phosphate buffer, 10% glycerol
-
-80C, 10% glycerol
P0AEK2
-80C, 50% glycerol
-
27C, 2 M NaCl, 24 h stable
-
-20C, stable for 2 months
-
-80C, 50% glycerol
-