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1.1.3.28: nucleoside oxidase

This is an abbreviated version!
For detailed information about nucleoside oxidase, go to the full flat file.

Reaction

Inosine
+
O2
=
9-riburonosylhypoxanthine
+
H2O

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.3 With oxygen as acceptor
                1.1.3.28 nucleoside oxidase

Systematic Name

Systematic Name on EC 1.1.3.28 - nucleoside oxidase

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SYSTEMATIC NAME
IUBMB Comments
nucleoside:oxygen 5'-oxidoreductase
Other purine and pyrimidine nucleosides (as well as 2'-deoxyribonucleosides) are substrates, but ribose and nucleotides are not substrates. The overall reaction takes place in two separate steps, with the 5'-dehydro nucleoside being released from the enzyme to serve as substrate for the second reaction. This enzyme differs from EC 1.1.3.39, nucleoside oxidase (H2O2-forming), as it produces water rather than hydrogen peroxide.