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1.1.3.15: (S)-2-hydroxy-acid oxidase

This is an abbreviated version!
For detailed information about (S)-2-hydroxy-acid oxidase, go to the full flat file.

Word Map on EC 1.1.3.15

Reaction

an (S)-2-hydroxy carboxylate
+
O2
=
a 2-oxo carboxylate
+
H2O2

Synonyms

(L)-2-HAOX, (S)-2-hydroxy-acid oxidase, peroxisomal, 2-hydroxy acid oxidase, CSUB_C1080, EC 1.1.3.1, GLO, Glo1, GLO3, Glo4, glycolate oxidase, GO, GO1, GOX, GOX1, GOX2, HAO1, Hao2, HAOX, HAOX1, HAOX2, HAOX3, hydroxy-acid oxidase A, hydroxy-acid oxidase B, hydroxyacid oxidase 1, hydroxyacid oxidase A, L-2-hydroxy acid oxidase, L-2-hydroxyacid oxidase A, L-alpha-hydroxy acid oxidase, L-amino acid oxidase, L-LAC-OX, L-lactate monooxygenase, L-lactate oxidase, L-LOx, lactate oxidase, LCHAO, LctO, lHAOX1, lHAOX2, long chain hydroxy acid oxidase, long chain l-2-hydroxy acid oxidase, long chain L-2-hydroxy acid oxidase 2, long-chain 2-hydroxy acid oxidase, long-chain L-alpha-hydroxy acid oxidase, LOX, More, NbS00005125g0015, NbS00060838g0004, Nbv5tr6245008, Os03g0786100, Os04g0623500, Os07g0616500, oxidase, L-2-hydroxy acid, RCOM_0631490, RCOM_0684800

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.3 With oxygen as acceptor
                1.1.3.15 (S)-2-hydroxy-acid oxidase

Natural Substrates Products

Natural Substrates Products on EC 1.1.3.15 - (S)-2-hydroxy-acid oxidase

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
(S)-lactate + O2
acetate + CO2 + H2O
show the reaction diagram
(S)-lactate + O2
pyruvate + H2O2
show the reaction diagram
2-hydroxycaproate + O2
2-oxocaproate + H2O2
show the reaction diagram
-
-
-
?
2-hydroxycaprylate + O2
2-oxocaprylate + H2O2
show the reaction diagram
-
-
-
?
2-hydroxyoctanoate + O2
2-oxooctanoate + H2O2
show the reaction diagram
-
substrates for isoenzymes HAOX1, HAOX2, preferred substrate for isoenzyme HAOX3
-
?
2-hydroxypalmitate + O2
2-oxopalmitate + H2O2
show the reaction diagram
an (S)-2-hydroxy carboxylate + O2
a 2-oxo carboxylate + H2O2
show the reaction diagram
D-2 -hydroxyisocaproate + O2
2-oxoisocaproate + H2O2
show the reaction diagram
D-lactate + O2
pyruvate + H2O2
show the reaction diagram
DL-2-hydroxybutyrate + O2
2-oxobutyrate + H2O2
show the reaction diagram
DL-2-hydroxycaproate + O2
2-oxocaproate + H2O2
show the reaction diagram
DL-2-hydroxyisocaproate + O2
2-oxoisocaproate + H2O2
show the reaction diagram
DL-2-hydroxyisovalerate + O2
2-oxoisovalerate + H2O2
show the reaction diagram
DL-2-hydroxyvalerate + O2
2-oxovalerate + H2O2
show the reaction diagram
DL-glycerate + O2
? + H2O2
show the reaction diagram
-
-
-
?
DL-lactate + O2
pyruvate + H2O2
show the reaction diagram
-
-
-
?
DL-methionine + O2
? + H2O2
show the reaction diagram
-
-
-
?
glycolate + acceptor
glyoxylate + reduced acceptor
show the reaction diagram
-
-
-
?
glycolate + O2
glyoxylate + H2O2
show the reaction diagram
glyoxylate + O2
? + H2O2
show the reaction diagram
glyoxylate thiohemiacetals + O2
? + H2O2
show the reaction diagram
-
possible natural substrates, i.e. glyoxylate thiohemiacetals of coemzyme A, D-phosphopantetheine, D-pantetheine, N-acetylcysteamine, 2-mercaptoethanol, DL-dihydrolipoate, propane-1,3-dithiol
-
?
homoserine + O2
? + H2O2
show the reaction diagram
-
traces of activity
-
?
L-2-hydroxy-4-methylthiobutanoic acid + O2
3-(methylthio)propanoate + HCO3-
show the reaction diagram
-
oxidative decarboxylation
-
?
L-2-hydroxyisocaproate + O2
2-oxoisocaproate + H2O2
show the reaction diagram
L-alanine + O2
? + H2O2
show the reaction diagram
-
low activity
-
?
L-isoleucine + O2
? + H2O2
show the reaction diagram
-
low activity
-
?
L-lactate + O2
pyruvate + H2O2
show the reaction diagram
L-leucine + O2
? + H2O2
show the reaction diagram
L-lysine + O2
? + H2O2
show the reaction diagram
-
-
-
?
L-mandelate + O2
? + H2O2
show the reaction diagram
-
-
-
?
L-methionine + O2
? + H2O2
show the reaction diagram
L-phenylalanine + O2
? + H2O2
show the reaction diagram
-
-
-
?
L-tryptophan + O2
? + H2O2
show the reaction diagram
L-tyrosine + O2
? + H2O2
show the reaction diagram
-
-
-
?
L-valine + O2
? + H2O2
show the reaction diagram
-
low activity
-
?
lactate + O2
pyruvate + H2O2
show the reaction diagram
thiol-glyoxylate adducts + O2
an oxalyl thioester + H2O2
show the reaction diagram
-
may be the physiological substrates
-
?
additional information
?
-