1.1.3.13: alcohol oxidase

This is an abbreviated version!
For detailed information about alcohol oxidase, go to the full flat file.

Reaction

Synonyms

alcohol oxidase 1, alcohol oxidase 2, alcohol oxidase A, alcohol oxidase B, alcohol oxidase I, alcohol: O2 oxidoreductase, alcohol:dioxygen-oxidoreductase, alcohol:O2 oxidoreductase, AlcOx, AOd, AOD1, AOext, AOint, AOX, AOX1, AOX2, AOXI, broad substrate specific alcohol oxidase, EC 1.1.3.31, ethanol oxidase, extracellular alcohol oxidase, FAD-dependent alcohol oxidase, FAO1, GLRG_05590, intracellular alcohol oxidase, long chain fatty alcohol oxidase, methanol oxidase, Mod1p, Mod2p, oxidase, alcohol, P-AOD, peroxisomal alcohol oxidase, primary alcohol oxidase, SCAO, short chain alcohol oxidase, short-chain alcohol oxidase, VAO, veratryl alcohol oxidase

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.3 With oxygen as acceptor

                1.1.3.13 alcohol oxidase

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Results	in table
9	Activating Compound
107	AA Sequence
38	Application
1	CAS Registry Number
13	Cloned(Commentary)
52	Cofactor
6	Crystallization (Commentary)
1	Expression
3	General Information
13	General Stability
145	Inhibitors
38	kcat/KM [mM/s]
8	Ki Value [mM]
147	KM Value [mM]
35	Localization
6	Metals/Ions
57	Molecular Weight [Da]
86	Natural Substrates/ Products (Substrates)
18	Organic Solvent Stability
184	Organism
6	Pathway
29	PDB ID
36	pH Optimum
13	pH Range
28	pH Stability
10	pI Value
3	Posttranslational Modification
21	Protein Variants
35	Purification (Commentary)
2	Reaction
3	Reaction Type
146	Reference
1	Renatured (Commentary)
44	Source Tissue
55	Specific Activity [micromol/min/mg]
17	Storage Stability
476	Substrates and Products (Substrate)
49	Subunits
108	Synonyms
1	Systematic Name
27	Temperature Optimum [°C]
5	Temperature Range [°C]
55	Temperature Stability [°C]
47	Turnover Number [1/s]

KM Value

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KM Value on EC 1.1.3.13 - alcohol oxidase

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KM VALUE [mM]

SUBSTRATE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

110 - 1600

(R)-1,2-Propanediol

4 entries

18.3

(R)-2-octanol

Aspergillus terreus

-

-

685404

36

1,4-butynediol

[Candida] boidinii

-

-

484909

0.0109 - 0.12

1-Decanol

2 entries

0.19

1-Heptanol

Colletotrichum graminicola

E3QHV8

pH 8, 23°C

762556

0.39 - 6.14

1-Hexanol

8 entries

0.0365 - 0.14

1-Octanol

2 entries

5.54

1-Pentanol

Ochrobactrum sp.

-

at pH 5.5 and 30°C

740872

2 - 45

1-propanol

6 entries

119

2,2'-sulfanediyldi(ethan-1-ol)

Phanerodontia chrysosporium

T2M2J4

pH 7.5, temperature not specified in the publication

762603

-

27.2

2-mercaptoethanol

Poria contigua

-

-

484908

261

2-propanol

Komagataella pastoris

-

pH 6.5, 22°C, immobilized enzyme

724647

3.2 - 10

2-propin-1-ol

2 entries

0.18

4-hepten-1-ol

Cornu aspersum

-

-

484921

0.44

4-Hydroxy-2-butynal

[Candida] boidinii

-

-

484909

0.42

4-nonen-1-ol

Cornu aspersum

-

-

484921

33.3

allyl alcohol

Ogataea angusta

-

-

484923

26.6

benzyl alcohol

Ogataea angusta

-

-

484923

198

Butane-1,4-diol

Phanerodontia chrysosporium

T2M2J4

pH 7.5, temperature not specified in the publication

762603

0.075

butanol

Cornu aspersum

-

-

484921

3.7 - 31

Cyclohexanol

4 entries

71.5

D-ribose

Phlebiopsis gigantea

-

-

484922

0.018

Decanol

Cornu aspersum

-

-

484921

12.3

diethylene glycol

Phanerodontia chrysosporium

T2M2J4

pH 7.5, temperature not specified in the publication

762603

0.038

Dodecanol

Cornu aspersum

-

-

484921

670

erythritol

Phlebiopsis gigantea

-

-

484922

0.13 - 22.5

ethanol

23 entries

0.95 - 9

ethylene glycol

3 entries

1.59 - 10.5

formaldehyde

8 entries

1.9

glycerol

Phanerodontia chrysosporium

T2M2J4

at pH 9.0 and 50°C

738128

167

glycolate

Ochrobactrum sp.

-

at pH 5.5 and 30°C

740872

0.0005 - 0.023

hexadecanol

2 entries

3

hexan-1-ol

Phanerodontia chrysosporium

T2M2J4

pH 7.5, temperature not specified in the publication

762603

12.9

hexane-1,6-diol

Phanerodontia chrysosporium

T2M2J4

pH 7.5, temperature not specified in the publication

762603

0.029

Hexanol

Cornu aspersum

-

-

484921

25

Isopropanol

Poria contigua

-

-

484908

15.8

Lactate

Ochrobactrum sp.

-

at pH 5.5 and 30°C

740872

0.019 - 89.58

methanol

25 entries

0.028 - 166

n-butanol

6 entries

1.86

n-dodecanol

Aspergillus terreus

-

-

685404

0.005 - 0.498

n-Heptanol

2 entries

0.05

n-Octanol

Aspergillus terreus

-

pH 8.5, 30°C, SCAO

671539

10.9

n-Pentanol

Phanerodontia chrysosporium

T2M2J4

at pH 9.0 and 50°C

738128

1.23 - 66

n-Propanol

5 entries

0.34 - 1

O2

5 entries

0.0032

Octanol

Cornu aspersum

-

-

484921

0.05

p-benzoquinone

Ogataea angusta

-

-

684534

52.6

pentane-1,4-diol

Phanerodontia chrysosporium

T2M2J4

pH 7.5, temperature not specified in the publication

762603

-

69.6

pentane-1,5-diol

Phanerodontia chrysosporium

T2M2J4

pH 7.5, temperature not specified in the publication

762603

2.3

phenyl-3-propanol

Aspergillus terreus

-

-

685404

0.067

Propanol

Cornu aspersum

-

-

484921

250

ribitol

Phlebiopsis gigantea

-

-

484922

0.0056

Tetradecanol

Cornu aspersum

-

-

484921

additional information

additional information

3 entries

-

110

(R)-1,2-Propanediol

Phanerodontia chrysosporium

T2M2J4

mutant F101S, pH 7.5, 23°C

762732

110

(R)-1,2-Propanediol

Phanerodontia chrysosporium

T2M2J4

mutant M103S, pH 7.5, 23°C

762732

1200

(R)-1,2-Propanediol

Phanerodontia chrysosporium

T2M2J4

mutant F101N, pH 7.5, 23°C

762732

1600

(R)-1,2-Propanediol

Phanerodontia chrysosporium

T2M2J4

wild-type, pH 7.5, 23°C

762732

0.0109

1-Decanol

Ochrobactrum sp.

-

at pH 5.5 and 30°C

740872

0.12

1-Decanol

Colletotrichum graminicola

E3QHV8

pH 8, 23°C

762556

0.39

1-Hexanol

Arthrobacter globiformis

Q7X2H8

mutant V355T/F357R, 30°C, pH 8

762910

0.41

1-Hexanol

Ochrobactrum sp.

-

at pH 5.5 and 30°C

740872

0.43

1-Hexanol

Arthrobacter globiformis

Q7X2H8

mutant S101A/V355T/F357R, 30°C, pH 8

762910

0.67

1-Hexanol

Arthrobacter globiformis

Q7X2H8

mutant S101A, 30°C, pH 8

762910

0.84

1-Hexanol

Arthrobacter globiformis

Q7X2H8

mutant S101A/V355T/F357R/M359R, 30°C, pH 8

762910

3.16

1-Hexanol

Arthrobacter globiformis

Q7X2H8

mutant S101A/D250G/F253R/V355T/F357R/M359R, 30°C, pH 8

762910

3.49

1-Hexanol

Arthrobacter globiformis

Q7X2H8

mutant M359R, 30°C, pH 8

762910

6.14

1-Hexanol

Arthrobacter globiformis

Q7X2H8

wild-type, 30°C, pH 8

762910

0.0365

1-Octanol

Ochrobactrum sp.

-

at pH 5.5 and 30°C

740872

0.14

1-Octanol

Colletotrichum graminicola

E3QHV8

pH 8, 23°C

762556

2

1-propanol

Phanerodontia chrysosporium

T2M2J4

mutant M103S, pH 7.5, 23°C

762732

4

1-propanol

Phanerodontia chrysosporium

T2M2J4

mutant F101S, pH 7.5, 23°C

762732

11

1-propanol

Phanerodontia chrysosporium

T2M2J4

mutant F101N, pH 7.5, 23°C

762732

24.91

1-propanol

Ogataea thermomethanolica (nom. inval.)

A0A067YIW8

pH 7.5, 30°C

763667

42.7

1-propanol

Phanerodontia chrysosporium

T2M2J4

at pH 9.0 and 50°C

738128

45

1-propanol

Phanerodontia chrysosporium

T2M2J4

wild-type, pH 7.5, 23°C

762732

3.2

2-propin-1-ol

Poria contigua

-

-

484908

10

2-propin-1-ol

[Candida] boidinii

-

-

484909

3.7

Cyclohexanol

Thermoanaerobacter brockii

-

wild-type, pH 7.5, 25°C

762911

5.8

Cyclohexanol

Thermoanaerobacter brockii

-

fusion protein with phenylacetone monooxygenase, pH 7.5, 25°C

762911

29

Cyclohexanol

Levilactobacillus brevis

-

fusion protein with phenylacetone monooxygenase, pH 7.5, 25°C

762911

31

Cyclohexanol

Levilactobacillus brevis

-

wild-type, pH 7.5, 25°C

762911

0.13

ethanol

Candida sp. (in: Saccharomycetales)

-

-

484907

0.75

ethanol

Komagataella pastoris

-

pH 6.5, 22°C, immobilized enzyme

724647

1

ethanol

Komagataella pastoris

-

-

484910

1

ethanol

Poria contigua

-

-

484908

1

ethanol

Phanerodontia chrysosporium

T2M2J4

mutant F101S, pH 7.5, 23°C

762732

1

ethanol

Phanerodontia chrysosporium

T2M2J4

mutant M103S, pH 7.5, 23°C

762732

1.97

ethanol

Phanerodontia chrysosporium

-

-

484919

2.9

ethanol

Phlebiopsis gigantea

-

-

484922

3.8

ethanol

Paecilomyces variotii

-

-

684630

5.41

ethanol

Ogataea thermomethanolica (nom. inval.)

A0A067YIW8

pH 7.5, 30°C

763667

6.6

ethanol

Ogataea angusta

-

pH 7.5, 30°C

672302

6.66

ethanol

Ogataea angusta

-

free enzyme

697064

8.23

ethanol

[Candida] methanosorbosa

-

-

484925

10

ethanol

Basidiomycota

-

-

484905

10.2

ethanol

Thermoascus aurantiacus

-

extracellular enzyme, pH 5.9, 30°C

674961

11

ethanol

Phanerodontia chrysosporium

T2M2J4

mutant F101N, pH 7.5, 23°C

762732

12

ethanol

Aspergillus ochraceus

-

-

688123

14.45

ethanol

Ogataea angusta

-

immobilized enzyme

697064

15

ethanol

Phanerodontia chrysosporium

T2M2J4

wild-type, pH 7.5, 23°C

762732

15.8

ethanol

Thermoascus aurantiacus

-

intracellular enzyme, pH 5.9, 30°C

674961

16.2

ethanol

Ogataea angusta

-

-

484923

20.2

ethanol

Penicillium purpurescens

-

pH 6.0, 40°C

699050

22.5

ethanol

Phanerodontia chrysosporium

T2M2J4

at pH 9.0 and 50°C

738128

0.95

ethylene glycol

Penicillium purpurescens

-

pH 6.0, 40°C

699050

1.25

ethylene glycol

Aspergillus ochraceus

-

-

688123

8 - 9

ethylene glycol

Komagataella pastoris

-

pH 6.5, 22°C, immobilized enzyme

724647

1.59

formaldehyde

Komagataella pastoris

-

pH 6.5, 22°C, immobilized enzyme

724647

2.6

formaldehyde

Ogataea angusta

-

-

484914

2.6

formaldehyde

Ogataea angusta

-

cosubstrate: p-benzoquinone

684534

3.5

formaldehyde

Pichia sp.

-

-

484911

4.9

formaldehyde

Paecilomyces variotii

-

-

684630

6.1

formaldehyde

Poria contigua

-

-

484908

9.5

formaldehyde

Ogataea angusta

-

cosubstrate: O2

684534

10.5

formaldehyde

Ogataea angusta

-

pH 7.5, 30°C

672302

0.0005

hexadecanol

Fungi

-

pH 7.5, 25°C

654228

0.023

hexadecanol

Cornu aspersum

-

-

484921

0.019

methanol

Candida sp. (in: Saccharomycetales)

-

-

484907

0.2

methanol

Poria contigua

-

-

484908

0.27

methanol

Ogataea thermomethanolica (nom. inval.)

A0A067YIW8

pH 7.5, 30°C

763667

0.4

methanol

Ogataea angusta

-

pH 7.5, 30°C

672302

0.47

methanol

Komagataella pastoris

-

pH 6.5, 22°C, immobilized enzyme

724647

0.5

methanol

Pichia sp.

-

-

484911

0.5

methanol

Thermoascus aurantiacus

-

extracellular enzyme, pH 5.9, 30°C

674961

0.6

methanol

Komagataella pastoris

P04842

at pH 7.4 and 30°C

741253

0.785

methanol

Phanerodontia chrysosporium

-

-

484919

1.4

methanol

Komagataella pastoris

-

oxygen concentration 0.19 mM

484910

1.52

methanol

Basidiomycota

-

-

484905

1.8

methanol

Phlebiopsis gigantea

-

-

484922

1.9

methanol

Paecilomyces variotii

-

-

684630

2

methanol

Phanerodontia chrysosporium

T2M2J4

wild-type, pH 7.5, 23°C

762732

2

methanol

Phanerodontia chrysosporium

T2M2J4

mutant F101S, pH 7.5, 23°C

762732

2

methanol

Phanerodontia chrysosporium

T2M2J4

mutant M103S, pH 7.5, 23°C

762732

2.15

methanol

Ogataea angusta

-

-

484923

2.3

methanol

Gloeophyllum trabeum

A8DPS4

-

684565

2.43

methanol

[Candida] methanosorbosa

-

-

484925

3

methanol

[Candida] boidinii

-

-

484909

3.1

methanol

Komagataella pastoris

-

oxygen concentration 0.93 mM

484910

13.5

methanol

Thermoascus aurantiacus

-

intracellular enzyme, pH 5.9, 30°C

674961

14

methanol

Phanerodontia chrysosporium

T2M2J4

mutant F101N, pH 7.5, 23°C

762732

36.6

methanol

Phanerodontia chrysosporium

T2M2J4

at pH 9.0 and 50°C

738128

89.58

methanol

Fungi

-

pH 7.5, 25°C

654228

0.028

n-butanol

Aspergillus terreus

-

pH 8.5, 30°C, SCAO

671539

2.79

n-butanol

Komagataella pastoris

-

pH 6.5, 22°C, immobilized enzyme

724647

21.3

n-butanol

Poria contigua

-

-

484908

35.9

n-butanol

Phanerodontia chrysosporium

-

-

484919

133

n-butanol

Basidiomycota

-

-

484905

166

n-butanol

Ogataea angusta

-

-

484923

0.005

n-Heptanol

Aspergillus terreus

-

pH 8.5, 30°C, SCAO

671539

0.498

n-Heptanol

Aspergillus terreus

-

-

685404

1.23

n-Propanol

Komagataella pastoris

-

pH 6.5, 22°C, immobilized enzyme

724647

8.3

n-Propanol

Poria contigua

-

-

484908

13.8

n-Propanol

Phanerodontia chrysosporium

-

-

484919

54.6

n-Propanol

Basidiomycota

-

-

484905

66

n-Propanol

Ogataea angusta

-

-

484923

0.34

O2

Ogataea angusta

-

-

684534

0.4

O2

Phlebiopsis gigantea

-

-

484922

0.4

O2

Komagataella pastoris

-

methanol concentration 1 mM

484910

0.7

O2

Komagataella pastoris

-

methanol concentration 10 mM

484910

1

O2

Komagataella pastoris

-

methanol concentration 100 mM

484910

additional information

additional information

Komagataella pastoris

-

kinetics

672860

-

additional information

additional information

Komagataella pastoris

-

kinetics

673395

-

additional information

additional information

Komagataella pastoris

-

Michaelis-Menten kinetics, overview

724647

-