1.1.1.50: 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)

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For detailed information about 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific), go to the full flat file.

Word Map on EC 1.1.1.50

1.1.1.50

aldo-keto

androgen

testosterone

reductases

beta-hydroxysteroids

alpha-reductase

beta-diol

androsterone

dihydrodiol

3alpha-hydroxysteroids

dihydrotestosterone

hydroxysteroids

alpha-dihydrotestosterone

alpha-androstane-3

3-ketosteroids

alpha-diol

trans-dihydrodiols

alpha-androstanediol

alpha-hsdh

15-hydroxyprostaglandin

beta-reductase

talalay

bile-acids

pre-receptor

akr1d1

9,10-phenanthrenequinone

ketosteroid

alpha-hydroxy-5

20-ketosteroid

alpha,17

alpha-reduced

chlordecone

17beta-hsd

alpha-dht

environmental protection

drug development

biotechnology

analysis

medicine

synthesis

Reaction

Synonyms

3 alpha-hydroxysteroid dehydrogenase, 3 alphaHD, 3-alpha hydroxysteroid dehydrogenase type 3, 3-alpha-HSD, 3alpha-HSD, 3alpha-HSD/CR, 3alpha-HSD3, 3alpha-HSOR, 3alpha-hydroxysteroid dehydrogenase, 3alpha-hydroxysteroid dehydrogenase type 3, 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase, 3alpha-hydroxysteroid oxido-reductase, 3alpha-hydroxysteroid oxidoreductase, 3alpha-hydroxysteroid-5beta-oxidoreductase, 3alpha-OR, 3alpha-oxidoreductase, 3alpha/3beta-hydroxysteroid dehydrogenase, 3alphaHSD, 3HSD, 5alpha-dihydroprogesterone 3alpha-hydroxysteroid oxidoreductase, AKR1C, AKR1C1, AKR1C1-4, AKR1C14, AKR1C17, AKR1C2, AKR1C3, AKR1C4, AKR1C9, aldo-keto reductase 1C2, bile-acid binding protein, chlordecone reductase, DD2, DD21, dihydrodiol dehydrogenase, HSD, HSD28, HSD29, hsdA, HSDH, hydroxyprostaglandin dehydrogenase, More, NAD(P)+-3alpha-hydroxysteroid dehydrogenase, NAD+-dependent 3alpha-HSD, NADP(H)-dependent 3alpha-HSD, NADPH:5alpha-dihydroprogesterone 3alpha-hydroxysteroid oxidoreductase, prostaglandin F2alpha-synthase, Ps3alphaHSD, PT3HSD, sterognost 3alpha dehydrogenase, 3alpha-hydroxy steroid, type 2 3alpha-hydroxysteroid dehydrogenase/type 5 17beta-hydroxysteroid dehydrogenase, type 3 3alpha-hydroxysteroid dehydrogenase, type 5 17beta-hydroxysteroid dehydrogenase, type I 3alpha-HSD

ECTree

1 Oxidoreductases

1.1 Acting on the CH-OH group of donors

1.1.1 With NAD⁺ or NADP⁺ as acceptor

1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)

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Results	in table
8	Activating Compound
395	AA Sequence
9	Application
1	CAS Registry Number
42	Cloned(Commentary)
103	Cofactor
12	Crystallization (Commentary)
170	Disease/ Diagnostics
3	Expression
12	General Information
5	General Stability
13	IC50 Value
110	Inhibitors
8	kcat/KM [mM/s]
26	Ki Value [mM]
182	KM Value [mM]
47	Localization
6	Metals/Ions
37	Molecular Weight [Da]
73	Natural Substrates/ Products (Substrates)
114	Organism
4	Pathway
12	PDB ID
34	pH Optimum
5	pH Range
2	pH Stability
56	Protein Variants
38	Purification (Commentary)
17	Reaction
3	Reaction Type
100	Reference
1	Renatured (Commentary)
112	Source Tissue
65	Specific Activity [micromol/min/mg]
9	Storage Stability
347	Substrates and Products (Substrate)
33	Subunits
168	Synonyms
1	Systematic Name
30	Temperature Optimum [°C]
3	Temperature Range [°C]
10	Temperature Stability [°C]
105	Turnover Number [1/s]

Expression

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Expression on EC 1.1.1.50 - 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)

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several fold induction of expression in the presence of steroid substrates

Comamonas testosteroni

P80702

697270

the 3alpha-HSOR mRNA ipsilateral expression of progesterone-treated hemiparkinsonian animals is significantly augmented compared to sham and hemiparkinsonian rats. On the other hand, 3alpha-HSOR mRNA expression is no different among groups when substantia nigra samples contralateral to lesion are considered

2 entries