1.1.1.45: L-gulonate 3-dehydrogenase
This is an abbreviated version!
For detailed information about L-gulonate 3-dehydrogenase, go to the full flat file.
Word Map on EC 1.1.1.45
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1.1.1.45
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protomer
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uronate
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medicine
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drosophila
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lens
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acetoacetate
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dehydrogenation
- 1.1.1.45
-
protomer
-
uronate
- medicine
- drosophila
- lens
- acetoacetate
-
dehydrogenation
Reaction
Synonyms
GDH, GuDH, L-3-aldonate dehydrogenase, L-3-aldonic dehydrogenase, L-3-hydroxyacid dehydrogenase, L-beta-hydroxy-acid-NAD-oxidoreductase, L-beta-hydroxyacid dehydrogenase, L-gulonate 3-dehydrogenase, L-gulonic acid dehydrogenase, More
ECTree
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Substrates Products
Substrates Products on EC 1.1.1.45 - L-gulonate 3-dehydrogenase
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REACTION DIAGRAM
L-gulonate + NADP+
3-dehydro-L-gulonate + NADPH + H+
NAD+ is preferred as cofactor
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-
r
L-gulonate + NAD+
3-dehydro-L-gulonate + NADH + H+
NAD+ is preferred as cofactor
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-
r
L-gulonic acid + NAD+
3-dehydro-L-gulonic acid + NADH + H+
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glucuronate-xylulose cycle
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-
?
L-gulonic acid + NAD+
3-dehydro-L-gulonic acid + NADH + H+
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-
-
-
?
L-gulonic acid + NAD+
3-dehydro-L-gulonic acid + NADH + H+
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-
-
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r
L-gulonic acid + NAD+
3-dehydro-L-gulonic acid + NADH + H+
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glucuronate-xylulose cycle
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-
?
L-gulonic acid + NAD+
3-dehydro-L-gulonic acid + NADH + H+
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stereospecificity for L-configuration of the beta-carbon hydroxyl group
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-
r
L-gulonic acid + NAD+
3-dehydro-L-gulonic acid + NADH + H+
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glucuronate-xylulose cycle
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-
?
L-gulonic acid + NAD+
3-dehydro-L-gulonic acid + NADH + H+
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stereospecificity for L-configuration of the beta-carbon hydroxyl group
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-
r
L-gulonic acid + NAD+
3-dehydro-L-gulonic acid + NADH + H+
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glucuronate-xylulose cycle
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r
?
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no substrates are: DL-2-hydroxybutanoate, DL-4-hydroxybutanoate, 2-butanol, DL-3-hydroxypropionate, L-threonine
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?
additional information
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active site structure and substrate recognition, importance of the dimeric state of the enzyme, overview
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?
additional information
?
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active site structure and substrate recognition, importance of the dimeric state of the enzyme, overview
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?
additional information
?
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no substrates are: L-arabonic acid, D-glucuronate, D-mannuronate, l-iduronate, 6-phospho-D-gluconate, L-serine, L-threonine, beta-D-hydroxy acids, acetoacetyl-CoA, acetoacetyl-S-pantetheine
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?