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1.1.1.406: galactitol 2-dehydrogenase (L-tagatose-forming)

This is an abbreviated version!
For detailed information about galactitol 2-dehydrogenase (L-tagatose-forming), go to the full flat file.

Reaction

galactitol
+
NAD+
=
D-tagatose
+
NADH
+
H+

Synonyms

galactitol dehydrogenase, GatDH, More

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.406 galactitol 2-dehydrogenase (L-tagatose-forming)

Systematic Name

Systematic Name on EC 1.1.1.406 - galactitol 2-dehydrogenase (L-tagatose-forming)

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SYSTEMATIC NAME
IUBMB Comments
galactitol:NAD+ 2-oxidoreductase (L-tagatose-forming)
The enzyme, characterized in the bacterium Rhodobacter sphaeroides, has a wide subtrate specificity. In addition to galactitol, it primarily oxidizes D-threitol and xylitol, and in addition to L-tagatose, it primarily reduces L-erythrulose, D-ribulose and L-glyceraldehyde. It is specific for NAD+. The enzyme also shows activity with D-tagatose (cf. EC 1.1.1.16, galactitol 2-dehydrogenase).