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1.1.1.383: ketol-acid reductoisomerase [NAD(P)+]

This is an abbreviated version!
For detailed information about ketol-acid reductoisomerase [NAD(P)+], go to the full flat file.

Reaction

(2R)-2,3-dihydroxy-3-methylbutanoate
+
NAD(P)+
=
(2S)-2-hydroxy-2-methyl-3-oxobutanoate
+
NAD(P)H
+
H+

Synonyms

ilvC, Shewana3_0355

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.383 ketol-acid reductoisomerase [NAD(P)+]

Substrates Products

Substrates Products on EC 1.1.1.383 - ketol-acid reductoisomerase [NAD(P)+]

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(2S)-2-hydroxy-2-methyl-3-oxobutanoate + NADH + H+
(2R)-2,3-dihydroxy-3-methylbutanoate + NAD+
show the reaction diagram
(2S)-2-hydroxy-2-methyl-3-oxobutanoate + NADPH + H+
(2R)-2,3-dihydroxy-3-methylbutanoate + NADP+
show the reaction diagram
(S)-2-acetolactate + NADH + H+
2,3-dihydroxy-3-methylbutanoate + NAD+
show the reaction diagram
(S)-2-acetolactate + NADPH + H+
2,3-dihydroxy-3-methylbutanoate + NADP+
show the reaction diagram