Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

1.1.1.37: malate dehydrogenase

This is an abbreviated version!
For detailed information about malate dehydrogenase, go to the full flat file.

Word Map on EC 1.1.1.37

Reaction

(S)-malate
+
NAD+
=
oxaloacetate
 +
NADH
 +
H+

Synonyms

(R)-2-hydroxyacid dehydrogenase, (S)-malate dehydrogenase, A8B73_11505, CaMDH, cMDH, cMDH -S, cMDH-L, cyMDH, cyMDH1, cyMDH2, cyMDH3, cytMDH, cytMDH1, cytosolic malate dehydrogenase, cytosolic malate dehydrogenase 1, cytosolic MDH, cytosolic NAD-dependent malate dehydrogenase, flo16, floury endosperm16, halophilic malate dehydrogenase, HmMalDH, L-malate dehydrogenase, L-malate dehydrogenases, L-malate-NAD oxidoreductase, L-malate-NAD-oxidoreductase, L-malate: NAD oxidoreductase, L-malate: NAD+ oxidoreductase, L-malate:NAD oxidoreductase, L-malate:NAD-oxidoreductase, L-MDH, LDH-like malate dehydrogenase, ldh0076, LEUM_0076, m-MDH, malate (NAD) dehydrogenase, malate dehydrogenase, malate dehydrogenase (NAD), malate dehydrogenase 1, malate dehydrogenase 2, malate: NAD oxidoreductase, MalDH, malic acid dehydrogenase, malic dehydrogenase, mbNAD-MDH, MDH, MDH A, MDH B1, MDH B2, Mdh1, MDH2, Mdh2a, Mdh2b, Mdh3, mitochondrial malate dehydrogenase, mitochondrial MDH, mMDH, mNAD-MDH, More, NAD+ malate dehydrogenase, NAD+-dependent malate dehydrogenase, NAD+-dependent MDH, NAD+-MDH enzymes, NAD-dependent cytosolic malate dehydrogenase, NAD-dependent malate dehydrogenase, NAD-dependent MalDH, NAD-dependent malic dehydrogenase, NAD-dependent MDH, NAD-L-malate dehydrogenase, NAD-linked malate dehydrogenase, NAD-malate dehydrogenase, NAD-malic dehydrogenase, NAD-MDH, NAD-specific malate dehydrogenase, NADP+-dependent malate dehydrogenase, Pcal_1699, pdNAD-MDH, peroxisomal malate dehydrogenase, peroxisomal NAD+-malate dehydrogenase 1, peroxisomal NAD+-malate dehydrogenase 2, plastid-localized NAD-dependent MDH, plastidial NAD+-dependent malate dehydrogenase, plastidial NAD-dependent malate dehydrogenase, plastidial NAD-dependent malate dehydrogenase 1, plNAD-MDH, PMDH, PMDH1, PMDH2, regulatory subunit of nucleic acid-conducting channel, s-MDH, SrMalDH, TaMDH, VEG69, Vegetative protein 69, YlMdh2p, [LDH-like] MDH

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.37 malate dehydrogenase

IC50 Value

IC50 Value on EC 1.1.1.37 - malate dehydrogenase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
IC50 VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.000059
(E)-3-(4-((3R,5R,7R)-adamantan-1-yl)phenoxy)-N-(5-(piperidine-1-carbonyl)-1,4-dihydroindeno[1,2-c]pyrazol-3-yl) acrylamide
Homo sapiens
pH and temperature not specified in the publication
0.0079
5-(3,4-dichlorobenzyl)-7,12-dihydroindolo[3,2-d][1]benzazepin-6(5H)-one
Sus scrofa
-
pH 8.5, 25°C
0.0105
5-(4-methylbenzyl)-7,12-dihydroindolo[3,2-d][1]benzazepin-6(5H)-one
Sus scrofa
-
pH 8.5, 25°C
0.0024
5-benzyl-9-bromo-7,12-dihydroindolo[3,2-d][1]benzazepin-6(5H)-one
Sus scrofa
-
pH 8.5, 25°C
0.0027
5-benzyl-9-chloro-7,12-dihydroindolo[3,2-d][1]benzazepin-6(5H)-one
Sus scrofa
-
pH 8.5, 25°C
0.0119
5-benzyl-9-methoxy-7,12-dihydroindolo[3,2-d][1]benzazepin-6(5H)-one
Sus scrofa
-
pH 8.5, 25°C
0.0062
5-benzyl-9-methyl-7,12-dihydroindolo[3,2-d][1]benzazepin-6(5H)-one
Sus scrofa
-
pH 8.5, 25°C
0.0016
5-benzyl-9-tert-butyl-7,12-dihydroindolo[3,2-d][1]benzazepin-6(5H)-one
Sus scrofa
-
pH 8.5, 25°C
0.0042
5-benzyl-9-trifluoromethyl-7,12-dihydroindolo[3,2-d][1]benzazepin-6(5H)-one
Sus scrofa
-
pH 8.5, 25°C
0.0011
9-bromo-5-(3,4-dichlorobenzyl)-7,12-dihydroindolo[3,2-d][1]benzazepin-6(5H)-one
Sus scrofa
-
pH 8.5, 25°C
0.0018
9-bromo-5-(4-methoxybenzyl)-7,12-dihydroindolo[3,2-d][1]benzazepin-6(5H)-one
Sus scrofa
-
pH 8.5, 25°C
0.0016
9-bromo-5-(4-methylbenzyl)-7,12-dihydroindolo[3,2-d][1]benzazepin-6(5H)-one
Sus scrofa
-
pH 8.5, 25°C
0.00077
9-tert-butyl-5-(3,4-dichlorobenzyl)-7,12-dihydroindolo[3,2-d][1]benzazepin-6(5H)-one
Sus scrofa
-
pH 8.5, 25°C
0.0099
butyl 6-oxo-5,6,7,12-tetrahydroindolo[3,2-d][1]benzazepine-9-carboxylate
Sus scrofa
-
pH 8.5, 25°C
0.02
ethyl 6-oxo-5,6,7,12-tetrahydroindolo[3,2-d][1]benzazepine-9-carboxylate
Sus scrofa
-
pH 8.5, 25°C
0.0115
gossypol
Plasmodium falciparum
IC50: 0.0115 mM
0.0043
hexyl 6-oxo-5,6,7,12-tetrahydroindolo[3,2-d][1]benzazepine-9-carboxylate
Sus scrofa
-
pH 8.5, 25°C
0.0135
methyl 6-oxo-5,6,7,12-tetrahydroindolo[3,2-d][1]benzazepine-9-carboxylate
Sus scrofa
-
pH 8.5, 25°C
0.0027
octyl 6-oxo-5,6,7,12-tetrahydroindolo[3,2-d][1]benzazepine-9-carboxylate
Sus scrofa
-
pH 8.5, 25°C
0.0044
pentyl 6-oxo-5,6,7,12-tetrahydroindolo[3,2-d][1]benzazepine-9-carboxylate
Sus scrofa
-
pH 8.5, 25°C
0.0062
propyl 6-oxo-5,6,7,12-tetrahydroindolo[3,2-d][1]benzazepine-9-carboxylate
Sus scrofa
-
pH 8.5, 25°C