1.1.1.352: 5'-hydroxyaverantin dehydrogenase

This is an abbreviated version!
For detailed information about 5'-hydroxyaverantin dehydrogenase, go to the full flat file.

Reaction

Synonyms

AdhA, alcohol dehydrogenase, HAVN dehydrogenase

ECTree

1 Oxidoreductases

1.1 Acting on the CH-OH group of donors

1.1.1 With NAD⁺ or NADP⁺ as acceptor

1.1.1.352 5'-hydroxyaverantin dehydrogenase

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Results	in table
5	AA Sequence
1	Cloned(Commentary)
3	Cofactor
1	IC50 Value
1	Inhibitors
2	KM Value [mM]
3	Localization
7	Molecular Weight [Da]
4	Natural Substrates/ Products (Substrates)
23	Organism
6	Pathway
2	pH Optimum
3	Purification (Commentary)
2	Reaction
9	Reference
6	Source Tissue
4	Specific Activity [micromol/min/mg]
11	Substrates and Products (Substrate)
10	Subunits
17	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
1	Temperature Range [°C]

Systematic Name

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Systematic Name on EC 1.1.1.352 - 5'-hydroxyaverantin dehydrogenase

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(1'S,5'S)-hydroxyaverantin:NAD+ oxidoreductase

Isolated from the aflatoxin-producing mold Aspergillus parasiticus [2]. Involved in aflatoxin biosynthesis. 5'-Oxoaverantin will spontaneously form averufin by intramolecular ketalisation. cf. EC 4.2.1.142, 5'-oxoaverantin cyclase.