1.1.1.350: ureidoglycolate dehydrogenase (NAD+)
This is an abbreviated version!
For detailed information about ureidoglycolate dehydrogenase (NAD+), go to the full flat file.
Reaction
Synonyms
(S)-ureidoglycolate dehydrogenase, AllD, ureidoglycolate dehydrogenase
ECTree
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Engineering
Engineering on EC 1.1.1.350 - ureidoglycolate dehydrogenase (NAD+)
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D141A
the mutant shows strongly reduced catalytic efficiency compared to the wild type enzyme
D141E
the mutant shows strongly reduced catalytic efficiency compared to the wild type enzyme
D141N
the mutant shows strongly reduced catalytic efficiency compared to the wild type enzyme
H44A
the mutant shows strongly reduced catalytic efficiency compared to the wild type enzyme
M251A
the mutant shows strongly reduced catalytic efficiency compared to the wild type enzyme
R259A
in the mutant enzyme R259A, the kcat value is approximately 21% that of the wild type enzyme, with about an 11fold increase in Km
S140A
the mutant shows strongly reduced catalytic efficiency compared to the wild type enzyme
S43A
the mutant shows strongly reduced catalytic efficiency compared to the wild type enzyme
Y52F
the mutant shows strongly reduced catalytic efficiency compared to the wild type enzyme