1.1.1.332: chanoclavine-I dehydrogenase

This is an abbreviated version!
For detailed information about chanoclavine-I dehydrogenase, go to the full flat file.

Reaction

Synonyms

ARB_04646, ChaDH, easD, fgaDH, FgaDHPr, ifgE

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.1 With NAD⁺ or NADP⁺ as acceptor

                1.1.1.332 chanoclavine-I dehydrogenase

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Results	in table
1	Activating Compound
8	AA Sequence
4	Cloned(Commentary)
10	Cofactor
16	General Information
2	Inhibitors
2	kcat/KM [mM/s]
6	KM Value [mM]
4	Metals/Ions
5	Molecular Weight [Da]
7	Natural Substrates/ Products (Substrates)
11	Organism
3	Pathway
1	Reaction
11	Reference
13	Substrates and Products (Substrate)
2	Subunits
32	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
4	Turnover Number [1/s]

Substrates Products

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Substrates Products on EC 1.1.1.332 - chanoclavine-I dehydrogenase

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

chanoclavine-I + NAD+

chanoclavine-I aldehyde + NADH + H+

11 entries

additional information

?

-

2 entries

chanoclavine-I + NAD+

chanoclavine-I aldehyde + NADH + H+

Aspergillus fumigatus

Q4WZ66

-

762642

-

-

r

chanoclavine-I + NAD+

chanoclavine-I aldehyde + NADH + H+

Aspergillus fumigatus

D3J0Z1

incubation of enzyme with chanoclavine-I aldehyde in the presence of NADH does not result in detectable chanoclavine-I, indicating a much lower reaction velocity of the reverse reaction

720615

-

-

?

chanoclavine-I + NAD+

chanoclavine-I aldehyde + NADH + H+

Aspergillus fumigatus Af293

Q4WZ66

-

762642

-

-

r

chanoclavine-I + NAD+

chanoclavine-I aldehyde + NADH + H+

Aspergillus fumigatus ATCC MYA-4609

Q4WZ66

-

762642

-

-

r

chanoclavine-I + NAD+

chanoclavine-I aldehyde + NADH + H+

Aspergillus fumigatus CBS 101355

Q4WZ66

-

762642

-

-

r

chanoclavine-I + NAD+

chanoclavine-I aldehyde + NADH + H+

Aspergillus fumigatus FGSC A1100

Q4WZ66

-

762642

-

-

r

chanoclavine-I + NAD+

chanoclavine-I aldehyde + NADH + H+

Penicillium camemberti

-

-

762642

-

-

r

chanoclavine-I + NAD+

chanoclavine-I aldehyde + NADH + H+

Penicillium camemberti NRRL 874

-

-

762642

-

-

r

chanoclavine-I + NAD+

chanoclavine-I aldehyde + NADH + H+

Penicillium roqueforti

-

-

763533

-

-

r

chanoclavine-I + NAD+

chanoclavine-I aldehyde + NADH + H+

Penicillium roqueforti FM164

-

-

763533

-

-

r

chanoclavine-I + NAD+

chanoclavine-I aldehyde + NADH + H+

Trichophyton benhamiae

D4AK45

-

720397

-

-

?

additional information

?

-

Penicillium roqueforti

-

LC-MS analysis of the in vitro assays

763533

-

-

-

additional information

?

-

Penicillium roqueforti FM164

-

LC-MS analysis of the in vitro assays

763533

-

-

-